Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule binding

CCDC88C HAUS6 CLASP1 MAP2 MDM1 NUMA1 TOGARAM1 CCDC61 KIF2C NIN

1.32e-073087110GO:0008017
GeneOntologyMolecularFunctiontubulin binding

CCDC88C HAUS6 CLASP1 MAP2 MDM1 NUMA1 TOGARAM1 CCDC61 KIF2C NIN

2.65e-064287110GO:0015631
GeneOntologyMolecularFunctioncytoskeletal protein binding

CCDC88C DLG5 HAUS6 CLASP1 MAP2 COBLL1 MDM1 NUMA1 TOGARAM1 CCDC61 UNC13A ADCY8 KIF2C NIN

2.73e-0510997114GO:0008092
GeneOntologyMolecularFunctionmicrotubule plus-end binding

CLASP1 NUMA1 KIF2C

6.32e-0522713GO:0051010
GeneOntologyMolecularFunctioncalcium- and calmodulin-responsive adenylate cyclase activity

ADCY1 ADCY8

1.24e-045712GO:0008294
GeneOntologyMolecularFunctionphospholipid binding

UNC13B SH3PXD2A GAB4 NUMA1 SNX18 SNX16 RUBCN UNC13A

7.13e-04548718GO:0005543
GeneOntologyMolecularFunctiondystroglycan binding

CLASP1 MAP2

8.04e-0412712GO:0002162
GeneOntologyMolecularFunctionphosphatidylinositol binding

SH3PXD2A GAB4 NUMA1 SNX18 SNX16 RUBCN

9.05e-04316716GO:0035091
GeneOntologyMolecularFunctionmicrotubule minus-end binding

NUMA1 NIN

1.27e-0315712GO:0051011
GeneOntologyMolecularFunctioncalmodulin binding

UNC13B MAP2 ADCY1 UNC13A ADCY8

1.36e-03230715GO:0005516
GeneOntologyMolecularFunctiondiacylglycerol binding

UNC13B UNC13A

1.45e-0316712GO:0019992
GeneOntologyMolecularFunctionadenylate cyclase activity

ADCY1 ADCY8

1.84e-0318712GO:0004016
GeneOntologyBiologicalProcessmicrotubule polymerization or depolymerization

CCDC88C HAUS6 CLASP1 MAP2 NUMA1 TOGARAM1 KIF2C NIN

1.01e-07168708GO:0031109
GeneOntologyBiologicalProcessdense core granule priming

UNC13B UNC13D UNC13A

1.49e-074703GO:0061789
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

UNC13B DLG5 HAUS6 CLASP1 MAP2 SACS PRICKLE1 SLF2 MDM1 NUMA1 SNX18 PRICKLE2 AMBRA1 MARCHF7 TOGARAM1 UNC13A PHLDB2

3.29e-0711897017GO:0044087
GeneOntologyBiologicalProcessregulation of microtubule-based process

CCDC88C HAUS6 IGBP1 CLASP1 MAP2 MDM1 NUMA1 TOGARAM1 PHLDB2

6.35e-07293709GO:0032886
GeneOntologyBiologicalProcessregulation of organelle organization

CCDC88C MRE11 HAUS6 CLASP1 MAP2 PRICKLE1 SLF2 MDM1 NUMA1 SNX18 PRICKLE2 AMBRA1 MARCHF7 TOGARAM1 ARID1A RUBCN PHLDB2

1.77e-0613427017GO:0033043
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

CCDC88C HAUS6 CLASP1 MAP2 NUMA1 TOGARAM1

1.79e-06108706GO:0031110
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

CCDC88C HAUS6 CLASP1 MAP2 NUMA1 TOGARAM1 PHLDB2

2.23e-06176707GO:0070507
GeneOntologyBiologicalProcessdense core granule localization

UNC13B MAP2 UNC13D UNC13A

2.34e-0628704GO:0032253
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

DLG5 CLASP1 MAP2 PRICKLE1 NUMA1 PRICKLE2 PHLDB2 KIF2C

2.52e-06257708GO:0007163
GeneOntologyBiologicalProcessmicrotubule polymerization

HAUS6 CLASP1 MAP2 NUMA1 TOGARAM1 NIN

2.86e-06117706GO:0046785
GeneOntologyBiologicalProcessmaintenance of postsynaptic density structure

PRICKLE1 PRICKLE2 CSMD2

3.10e-069703GO:0099562
GeneOntologyBiologicalProcessregulation of microtubule polymerization

HAUS6 CLASP1 MAP2 NUMA1 TOGARAM1

3.70e-0669705GO:0031113
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CCDC88C HAUS6 CLASP1 MAP2 PRICKLE1 MDM1 NUMA1 TOGARAM1 CCDC61 PHLDB2 KIF2C NIN

4.96e-067207012GO:0000226
GeneOntologyBiologicalProcessorganelle assembly

DNHD1 HAUS6 MYOM1 CLASP1 PRICKLE1 MDM1 NUMA1 SNX18 PRICKLE2 AMBRA1 MARCHF7 TOGARAM1 ALPK1 CSMD2 CCDC61

5.02e-0611387015GO:0070925
GeneOntologyBiologicalProcesssecretory granule localization

UNC13B MAP2 UNC13D UNC13A

5.22e-0634704GO:0032252
GeneOntologyBiologicalProcessregulation of basement membrane organization

CLASP1 NID1 PHLDB2

6.06e-0611703GO:0110011
GeneOntologyBiologicalProcessmicrotubule-based process

DNHD1 CCDC88C HAUS6 IGBP1 CLASP1 MAP2 PRICKLE1 MDM1 NUMA1 TOGARAM1 CCDC61 PHLDB2 KIF2C NIN

1.05e-0510587014GO:0007017
GeneOntologyBiologicalProcessdense core granule docking

UNC13B UNC13A

1.14e-052702GO:0061790
GeneOntologyBiologicalProcessbasement membrane organization

CLASP1 PRICKLE1 NID1 PHLDB2

1.36e-0543704GO:0071711
GeneOntologyBiologicalProcessdense core granule exocytosis

UNC13B UNC13D UNC13A

1.65e-0515703GO:1990504
GeneOntologyBiologicalProcessmaintenance of postsynaptic specialization structure

PRICKLE1 PRICKLE2 CSMD2

2.46e-0517703GO:0098880
GeneOntologyBiologicalProcesspositive regulation of CREB transcription factor activity

CRTC3 ADCY1 ADCY8

2.95e-0518703GO:0032793
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

UNC13B HAUS6 CLASP1 MAP2 SLF2 NUMA1 AMBRA1 TOGARAM1 UNC13A

3.96e-05489709GO:0043254
GeneOntologyBiologicalProcessmicrotubule depolymerization

CCDC88C CLASP1 MAP2 KIF2C

7.48e-0566704GO:0007019
GeneOntologyBiologicalProcesscell cycle process

MRE11 HAUS6 CLASP1 PRICKLE1 SLF2 MDM1 NUMA1 SNX18 AMBRA1 ARID1A CLOCK CCDC61 CABLES1 KIF2C NIN

7.99e-0514417015GO:0022402
GeneOntologyBiologicalProcessestablishment of organelle localization

UNC13B CLASP1 MAP2 GAB4 NUMA1 UNC13D CBL UNC13A KIF2C

9.24e-05546709GO:0051656
GeneOntologyBiologicalProcesspositive regulation of basement membrane assembly involved in embryonic body morphogenesis

CLASP1 PHLDB2

1.13e-045702GO:1904261
GeneOntologyBiologicalProcessregulation of basement membrane assembly involved in embryonic body morphogenesis

CLASP1 PHLDB2

1.13e-045702GO:1904259
GeneOntologyBiologicalProcessnegative regulation of wound healing, spreading of epidermal cells

CLASP1 PHLDB2

1.13e-045702GO:1903690
GeneOntologyBiologicalProcessbasement membrane assembly involved in embryonic body morphogenesis

CLASP1 PHLDB2

1.13e-045702GO:2001197
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex assembly

UNC13B CLASP1 SLF2 NUMA1 AMBRA1 TOGARAM1

1.21e-04227706GO:0031334
GeneOntologyBiologicalProcessorganelle localization

UNC13B CLASP1 MAP2 GAB4 NUMA1 UNC13D POLR2M CBL UNC13A KIF2C

1.24e-047037010GO:0051640
GeneOntologyBiologicalProcessregulation of protein polymerization

HAUS6 CLASP1 MAP2 NUMA1 AMBRA1 TOGARAM1

1.33e-04231706GO:0032271
GeneOntologyBiologicalProcessmicrotubule bundle formation

CCDC88C CLASP1 MAP2 NUMA1 TOGARAM1

1.34e-04145705GO:0001578
GeneOntologyBiologicalProcessprotein polymerization

HAUS6 CLASP1 MAP2 NUMA1 AMBRA1 TOGARAM1 NIN

1.37e-04334707GO:0051258
GeneOntologyBiologicalProcessregulation of double-strand break repair

MRE11 EPC2 ING3 SLF2 ARID1A

1.39e-04146705GO:2000779
GeneOntologyBiologicalProcesspositive regulation of cellular component biogenesis

UNC13B DLG5 CLASP1 SLF2 NUMA1 SNX18 AMBRA1 TOGARAM1 PHLDB2

1.50e-04582709GO:0044089
GeneOntologyBiologicalProcessspindle assembly

HAUS6 CLASP1 PRICKLE1 NUMA1 CCDC61

1.73e-04153705GO:0051225
GeneOntologyBiologicalProcesschromosome segregation

MRE11 HAUS6 CLASP1 PRICKLE1 NUMA1 ARID1A CCDC61 KIF2C

1.74e-04465708GO:0007059
GeneOntologyBiologicalProcessnuclear chromosome segregation

MRE11 CLASP1 PRICKLE1 NUMA1 ARID1A CCDC61 KIF2C

2.03e-04356707GO:0098813
GeneOntologyBiologicalProcesspostsynaptic density assembly

PRICKLE1 PRICKLE2 CSMD2

2.08e-0434703GO:0097107
GeneOntologyBiologicalProcesssister chromatid segregation

CLASP1 PRICKLE1 NUMA1 ARID1A CCDC61 KIF2C

2.23e-04254706GO:0000819
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

CLASP1 NUMA1 TOGARAM1

2.68e-0437703GO:0031116
GeneOntologyBiologicalProcessnegative regulation of microtubule depolymerization

CCDC88C CLASP1 MAP2

2.90e-0438703GO:0007026
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

EPC2 ING3 SLF2 ARID1A

3.07e-0495704GO:2000781
GeneOntologyBiologicalProcessmaintenance of synapse structure

PRICKLE1 PRICKLE2 CSMD2

3.38e-0440703GO:0099558
GeneOntologyBiologicalProcessestablishment of cell polarity

CLASP1 MAP2 PRICKLE1 NUMA1 PHLDB2

3.39e-04177705GO:0030010
GeneOntologyBiologicalProcessmicrotubule organizing center organization

HAUS6 CLASP1 MDM1 CCDC61 NIN

3.57e-04179705GO:0031023
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

CCDC88C CLASP1 MAP2 RUBCN

3.73e-04100704GO:0043242
GeneOntologyBiologicalProcessregulation of organelle assembly

PRICKLE1 MDM1 NUMA1 SNX18 PRICKLE2 MARCHF7

3.76e-04280706GO:1902115
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization or depolymerization

CLASP1 NUMA1 TOGARAM1

3.91e-0442703GO:0031112
GeneOntologyBiologicalProcessregulation of microtubule depolymerization

CCDC88C CLASP1 MAP2

3.91e-0442703GO:0031114
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

CLASP1 NUMA1 AMBRA1 TOGARAM1

4.02e-04102704GO:0032273
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

UNC13B MYOM1 CLASP1 GAB4 UNC13D UNC13A ADCY8

4.35e-04404707GO:1903532
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

PRICKLE1 PRICKLE2 CSMD2

4.49e-0444703GO:0098698
GeneOntologyBiologicalProcessprotein-containing complex disassembly

CCDC88C CLASP1 MAP2 ARID1A RUBCN KIF2C

4.61e-04291706GO:0032984
GeneOntologyBiologicalProcesspositive regulation of exocytosis

UNC13B CLASP1 GAB4 UNC13D

4.82e-04107704GO:0045921
GeneOntologyBiologicalProcesspresynaptic dense core vesicle exocytosis

UNC13B UNC13A

5.02e-0410702GO:0099525
GeneOntologyBiologicalProcessexcitatory synapse assembly

PRICKLE1 PRICKLE2 CSMD2

5.12e-0446703GO:1904861
GeneOntologyBiologicalProcessnegative regulation of cytoskeleton organization

CCDC88C CLASP1 MAP2 MDM1 PHLDB2

5.16e-04194705GO:0051494
GeneOntologyBiologicalProcessmitotic cell cycle process

MRE11 CLASP1 PRICKLE1 NUMA1 SNX18 AMBRA1 ARID1A CCDC61 CABLES1 KIF2C

5.86e-048547010GO:1903047
GeneOntologyBiologicalProcesscAMP biosynthetic process

ADCY1 ADCY8

6.12e-0411702GO:0006171
GeneOntologyBiologicalProcessregulation of wound healing, spreading of epidermal cells

CLASP1 PHLDB2

6.12e-0411702GO:1903689
GeneOntologyBiologicalProcesspositive regulation of secretion

UNC13B MYOM1 CLASP1 GAB4 UNC13D UNC13A ADCY8

6.75e-04435707GO:0051047
GeneOntologyBiologicalProcessnegative regulation of microtubule polymerization or depolymerization

CCDC88C CLASP1 MAP2

6.94e-0451703GO:0031111
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

CCDC88C HAUS6 CLASP1 MAP2 NUMA1 TOGARAM1 PHLDB2

7.03e-04438707GO:1902903
GeneOntologyBiologicalProcessbasement membrane assembly

CLASP1 PHLDB2

7.33e-0412702GO:0070831
GeneOntologyBiologicalProcessneuronal dense core vesicle exocytosis

UNC13B UNC13A

7.33e-0412702GO:0099011
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

CCDC88C HAUS6 CLASP1 MAP2 MDM1 NUMA1 TOGARAM1 PHLDB2

7.51e-04579708GO:0051493
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

CLASP1 PRICKLE1 NUMA1 CCDC61 KIF2C

7.70e-04212705GO:0000070
GeneOntologyBiologicalProcessastral microtubule organization

CLASP1 NUMA1

8.64e-0413702GO:0030953
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

CCDC88C PRICKLE1 PRICKLE2

8.65e-0455703GO:0060071
GeneOntologyBiologicalProcessregulation of cellular response to stress

MRE11 EPC2 IGBP1 ING3 SLF2 MARCHF7 ARID1A ADCY8

9.26e-04598708GO:0080135
GeneOntologyBiologicalProcessmicrotubule nucleation

HAUS6 CLASP1 NIN

9.61e-0457703GO:0007020
GeneOntologyBiologicalProcessestablishment of vesicle localization

UNC13B CLASP1 MAP2 UNC13D UNC13A

9.85e-04224705GO:0051650
GeneOntologyBiologicalProcessspindle organization

HAUS6 CLASP1 PRICKLE1 NUMA1 CCDC61

9.85e-04224705GO:0007051
GeneOntologyBiologicalProcessregulation of synaptic vesicle priming

UNC13B UNC13A

1.01e-0314702GO:0010807
GeneOntologyBiologicalProcesspositive regulation of synaptic plasticity

UNC13A ADCY8

1.01e-0314702GO:0031915
GeneOntologyBiologicalProcesspostsynaptic density organization

PRICKLE1 PRICKLE2 CSMD2

1.01e-0358703GO:0097106
GeneOntologyBiologicalProcessextracellular matrix assembly

CLASP1 PRICKLE1 PHLDB2

1.06e-0359703GO:0085029
GeneOntologyBiologicalProcessmembraneless organelle assembly

HAUS6 MYOM1 CLASP1 PRICKLE1 MDM1 NUMA1 CCDC61

1.13e-03475707GO:0140694
GeneOntologyBiologicalProcesscellular component disassembly

CCDC88C CLASP1 MAP2 PRICKLE1 AMBRA1 ARID1A RUBCN KIF2C

1.13e-03617708GO:0022411
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix assembly

CLASP1 PHLDB2

1.16e-0315702GO:1901203
GeneOntologyBiologicalProcessembryonic body morphogenesis

CLASP1 PHLDB2

1.16e-0315702GO:0010172
GeneOntologyBiologicalProcessregulation of DNA repair

MRE11 EPC2 ING3 SLF2 ARID1A

1.20e-03234705GO:0006282
GeneOntologyBiologicalProcessbody morphogenesis

CLASP1 PRICKLE1 PHLDB2

1.34e-0364703GO:0010171
GeneOntologyBiologicalProcesssupramolecular fiber organization

CCDC88C HAUS6 MYOM1 CLASP1 MAP2 NUMA1 TOGARAM1 PHLDB2 KIF2C NIN

1.40e-039577010GO:0097435
GeneOntologyBiologicalProcesscell junction maintenance

PRICKLE1 PRICKLE2 CSMD2

1.41e-0365703GO:0034331
GeneOntologyBiologicalProcesspositive regulation of DNA repair

EPC2 ING3 SLF2 ARID1A

1.42e-03143704GO:0045739
GeneOntologyBiologicalProcessprotein depolymerization

CCDC88C CLASP1 MAP2 KIF2C

1.46e-03144704GO:0051261
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

CCDC88C CLASP1 MAP2 RUBCN

1.46e-03144704GO:0043244
GeneOntologyBiologicalProcesscytoplasmic microtubule organization

CCDC88C CLASP1 NUMA1

1.47e-0366703GO:0031122
GeneOntologyBiologicalProcesssynaptic vesicle docking

UNC13B UNC13A

1.49e-0317702GO:0016081
GeneOntologyBiologicalProcessnuclear receptor-mediated glucocorticoid signaling pathway

ARID1A CLOCK

1.49e-0317702GO:0042921
GeneOntologyBiologicalProcessvesicle localization

UNC13B CLASP1 MAP2 UNC13D UNC13A

1.52e-03247705GO:0051648
GeneOntologyBiologicalProcesspresynaptic modulation of chemical synaptic transmission

UNC13B NR3C2 ADCY1

1.54e-0367703GO:0099171
GeneOntologyBiologicalProcesscellular response to forskolin

ADCY1 ADCY8

1.68e-0318702GO:1904322
GeneOntologyBiologicalProcessnuclear receptor-mediated corticosteroid signaling pathway

ARID1A CLOCK

1.68e-0318702GO:0031958
GeneOntologyBiologicalProcessmitotic spindle organization

CLASP1 PRICKLE1 NUMA1 CCDC61

1.74e-03151704GO:0007052
GeneOntologyBiologicalProcesspostsynaptic specialization organization

PRICKLE1 PRICKLE2 CSMD2

1.81e-0371703GO:0099084
GeneOntologyCellularComponentcell cortex region

UNC13B CLASP1 NUMA1 NR3C2 UNC13A PHLDB2

9.89e-0945726GO:0099738
GeneOntologyCellularComponentcytoplasmic region

UNC13B DNHD1 CLASP1 MAP2 NUMA1 AMBRA1 TOGARAM1 NR3C2 UNC13A PHLDB2

4.21e-073607210GO:0099568
GeneOntologyCellularComponentneuron to neuron synapse

UNC13B DLG5 NAPEPLD MAP2 PRICKLE1 PRICKLE2 NR3C2 CSMD2 ADCY1 ADCY8

1.18e-055237210GO:0098984
GeneOntologyCellularComponentcell cortex

UNC13B CLASP1 NUMA1 POLR2M NR3C2 UNC13A PHLDB2 CYTIP

4.06e-05371728GO:0005938
GeneOntologyCellularComponentmicrotubule organizing center

CCDC88C DLG5 HAUS6 CLASP1 MDM1 NUMA1 MARCHF7 TOGARAM1 ALPK1 CCDC61 KIF2C NIN

6.54e-059197212GO:0005815
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

UNC13B NR3C2 UNC13A

6.60e-0523723GO:0098831
GeneOntologyCellularComponentpiccolo histone acetyltransferase complex

EPC2 ING3

6.99e-054722GO:0032777
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

UNC13B NAPEPLD ADCY1 ADCY8

8.42e-0567724GO:0098686
GeneOntologyCellularComponentmicrotubule

HAUS6 IGBP1 CLASP1 MAP2 MDM1 NUMA1 TOGARAM1 KIF2C NIN

8.69e-05533729GO:0005874
GeneOntologyCellularComponentcytoplasmic microtubule

CLASP1 NUMA1 TOGARAM1 KIF2C NIN

9.61e-05133725GO:0005881
GeneOntologyCellularComponentglutamatergic synapse

UNC13B DLG5 MAP2 PRICKLE1 PRICKLE2 NR3C2 CSMD2 ADCY1 UNC13A ADCY8 KIF2C

1.04e-048177211GO:0098978
GeneOntologyCellularComponentcortical microtubule cytoskeleton

CLASP1 NUMA1

1.16e-045722GO:0030981
GeneOntologyCellularComponentmicrotubule plus-end

CLASP1 NUMA1 KIF2C

1.21e-0428723GO:0035371
GeneOntologyCellularComponentpostsynaptic density

DLG5 MAP2 PRICKLE1 PRICKLE2 NR3C2 CSMD2 ADCY1 ADCY8

1.58e-04451728GO:0014069
GeneOntologyCellularComponentasymmetric synapse

DLG5 MAP2 PRICKLE1 PRICKLE2 NR3C2 CSMD2 ADCY1 ADCY8

2.31e-04477728GO:0032279
GeneOntologyCellularComponentcilium

DNHD1 DLG5 NAPEPLD PTCHD3 MDM1 AMBRA1 TOGARAM1 ALPK1 CBL CCDC61 NIN

2.37e-048987211GO:0005929
GeneOntologyCellularComponentbasal cortex

CLASP1 PHLDB2

2.43e-047722GO:0045180
GeneOntologyCellularComponentcentrosome

CCDC88C HAUS6 CLASP1 MDM1 NUMA1 MARCHF7 ALPK1 CCDC61 KIF2C NIN

2.95e-047707210GO:0005813
GeneOntologyCellularComponentmicrotubule end

CLASP1 NUMA1 KIF2C

3.03e-0438723GO:1990752
GeneOntologyCellularComponentpostsynaptic specialization

DLG5 MAP2 PRICKLE1 PRICKLE2 NR3C2 CSMD2 ADCY1 ADCY8

3.30e-04503728GO:0099572
GeneOntologyCellularComponentcentriolar subdistal appendage

CCDC61 NIN

5.17e-0410722GO:0120103
GeneOntologyCellularComponentsupramolecular fiber

HAUS6 IGBP1 MYOM1 CLASP1 MAP2 MDM1 NUMA1 STYXL2 TOGARAM1 POLR2M KIF2C NIN

6.50e-0411797212GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

HAUS6 IGBP1 MYOM1 CLASP1 MAP2 MDM1 NUMA1 STYXL2 TOGARAM1 POLR2M KIF2C NIN

6.90e-0411877212GO:0099081
GeneOntologyCellularComponentpresynaptic active zone

UNC13B NR3C2 UNC13A ADCY8

1.43e-03141724GO:0048786
GeneOntologyCellularComponentmicrotubule associated complex

DNHD1 HAUS6 MAP2 KIF2C

2.32e-03161724GO:0005875
GeneOntologyCellularComponentpostsynapse

DLG5 NAPEPLD MAP2 PRICKLE1 PRICKLE2 NR3C2 CSMD2 ADCY1 ADCY8 KIF2C

2.47e-0310187210GO:0098794
GeneOntologyCellularComponentspindle microtubule

HAUS6 CLASP1 NUMA1

3.27e-0386723GO:0005876
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

HAUS6 IGBP1 CLASP1 MAP2 MDM1 NUMA1 TOGARAM1 KIF2C NIN

3.63e-03899729GO:0099513
GeneOntologyCellularComponentdistal axon

UNC13B MAP2 SNX18 CBL UNC13A NIN

3.85e-03435726GO:0150034
GeneOntologyCellularComponentmitotic spindle

HAUS6 CLASP1 NUMA1 NIN

5.13e-03201724GO:0072686
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

EPC2 ING3

5.43e-0332722GO:0035267
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

EPC2 ING3

5.43e-0332722GO:0043189
GeneOntologyCellularComponentspindle

HAUS6 CLASP1 NUMA1 ALPK1 KIF2C NIN

5.65e-03471726GO:0005819
DomainMunc13_dom-2

UNC13B UNC13D UNC13A

5.01e-075703IPR014772
DomainMembr_traf_MHD

UNC13B UNC13D UNC13A

5.01e-075703PF10540
DomainMHD2

UNC13B UNC13D UNC13A

5.01e-075703PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13D UNC13A

5.01e-075703IPR019558
DomainDUF1041

UNC13B UNC13D UNC13A

1.75e-067703PF06292
DomainMunc13_1

UNC13B UNC13D UNC13A

1.75e-067703IPR014770
DomainCAPS_dom

UNC13B UNC13D UNC13A

1.75e-067703IPR010439
DomainMHD1

UNC13B UNC13D UNC13A

1.75e-067703PS51258
DomainC2

UNC13B HECW1 WWP1 UNC13D UNC13A RASAL2

9.63e-06131706PF00168
DomainC2

UNC13B HECW1 WWP1 UNC13D UNC13A RASAL2

1.24e-05137706SM00239
DomainC2

UNC13B HECW1 WWP1 UNC13D UNC13A RASAL2

1.53e-05142706PS50004
Domain-

UNC13B HECW1 WWP1 UNC13D UNC13A RASAL2

1.93e-051487062.60.40.150
DomainC2_dom

UNC13B HECW1 WWP1 UNC13D UNC13A RASAL2

3.45e-05164706IPR000008
DomainUnc-13

UNC13B UNC13A

4.14e-053702IPR027080
DomainLIM3_prickle

PRICKLE1 PRICKLE2

4.14e-053702IPR033727
DomainLIM2_prickle

PRICKLE1 PRICKLE2

4.14e-053702IPR033726
DomainPET_prickle

PRICKLE1 PRICKLE2

4.14e-053702IPR033723
DomainDUF1041

UNC13B UNC13A

1.37e-045702SM01145
DomainPET

PRICKLE1 PRICKLE2

2.06e-046702PF06297
DomainPET_domain

PRICKLE1 PRICKLE2

2.06e-046702IPR010442
DomainPET

PRICKLE1 PRICKLE2

2.06e-046702PS51303
DomainAC_N

ADCY1 ADCY8

3.82e-048702IPR032628
DomainAdcy

ADCY1 ADCY8

3.82e-048702IPR030672
DomainAC_N

ADCY1 ADCY8

3.82e-048702PF16214
DomainPX

SH3PXD2A SNX18 SNX16

5.98e-0444703SM00312
DomainPX

SH3PXD2A SNX18 SNX16

8.21e-0449703PF00787
DomainPX

SH3PXD2A SNX18 SNX16

8.71e-0450703PS50195
Domain-

SH3PXD2A SNX18 SNX16

9.23e-04517033.30.1520.10
DomainPhox

SH3PXD2A SNX18 SNX16

9.77e-0452703IPR001683
DomainA/G_cyclase_CS

ADCY1 ADCY8

1.82e-0317702IPR018297
DomainNucleotide_cyclase

ADCY1 ADCY8

2.04e-0318702IPR029787
Domain-

ADCY1 ADCY8

2.04e-03187023.30.70.1230
DomainGUANYLATE_CYCLASE_1

ADCY1 ADCY8

2.27e-0319702PS00452
DomainGuanylate_cyc

ADCY1 ADCY8

2.27e-0319702PF00211
DomainGUANYLATE_CYCLASE_2

ADCY1 ADCY8

2.27e-0319702PS50125
DomainA/G_cyclase

ADCY1 ADCY8

2.27e-0319702IPR001054
DomainCYCc

ADCY1 ADCY8

2.27e-0319702SM00044
DomainHECT

HECW1 WWP1

4.57e-0327702PF00632
DomainHECTc

HECW1 WWP1

4.57e-0327702SM00119
DomainHECT_dom

HECW1 WWP1

4.57e-0327702IPR000569
DomainHECT

HECW1 WWP1

4.57e-0327702PS50237
DomainMAGE

TRO MAGEB18

7.19e-0334702SM01373
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCDC88C SRRM1 DLG5 CRTC3 CLASP1 MAP2 SLF2 SH3PXD2A COBLL1 NR3C2 ALPK1 RFX7 CBL RASAL2 PHLDB2 KIF2C

2.45e-11861731636931259
Pubmed

Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.

CLASP1 PRICKLE1 PRICKLE2 PHLDB2

8.91e-11573427378169
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CCDC88C CRTC3 IGBP1 CLASP1 SH3PXD2A SNX18 ARID1A CBL RASAL2 PHLDB2 KIF2C NIN

1.55e-10446731224255178
Pubmed

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.

UNC13B UNC13D UNC13A

8.84e-08573326575293
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13B UNC13D UNC13A

4.93e-07873325609709
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SETD1A CRTC3 ING3 TRO TMEM151B NUMA1 RAD54L2 RNF115

3.41e-0643073835044719
Pubmed

Deficits in behavioral sensitization and dopaminergic responses to methamphetamine in adenylyl cyclase 1/8-deficient mice.

ADCY1 ADCY8

4.35e-06273226146906
Pubmed

Temporal and regional regulation of gene expression by calcium-stimulated adenylyl cyclase activity during fear memory.

ADCY1 ADCY8

4.35e-06273220976279
Pubmed

Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation.

ADCY1 ADCY8

4.35e-06273214585998
Pubmed

Cyclic AMP-dependent positive feedback signaling pathways in the cortex contributes to visceral pain.

ADCY1 ADCY8

4.35e-06273231665810
Pubmed

Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses.

ADCY1 ADCY8

4.35e-06273216914643
Pubmed

Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors.

ADCY1 ADCY8

4.35e-06273217121841
Pubmed

Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain.

ADCY1 ADCY8

4.35e-06273215745964
Pubmed

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.

UNC13B UNC13A

4.35e-06273212070347
Pubmed

Regulation of insulin exocytosis by Munc13-1.

UNC13B UNC13A

4.35e-06273212871971
Pubmed

Genetic elimination of behavioral sensitization in mice lacking calmodulin-stimulated adenylyl cyclases.

ADCY1 ADCY8

4.35e-06273212441059
Pubmed

Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.

UNC13B UNC13A

4.35e-06273217561838
Pubmed

Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex.

PRICKLE1 PRICKLE2

4.35e-06273234613779
Pubmed

Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.

UNC13B UNC13A

4.35e-06273223070049
Pubmed

Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment.

ADCY1 ADCY8

4.35e-06273219479030
Pubmed

Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP.

ADCY1 ADCY8

4.35e-06273210482244
Pubmed

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.

UNC13B UNC13A

4.35e-06273228489077
Pubmed

Enhanced presynaptic neurotransmitter release in the anterior cingulate cortex of mice with chronic pain.

ADCY1 ADCY8

4.35e-06273216943548
Pubmed

Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity.

ADCY1 ADCY8

4.35e-06273215843614
Pubmed

Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies.

ADCY1 ADCY8

4.35e-06273218222416
Pubmed

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.

UNC13B UNC13A

4.35e-06273210440375
Pubmed

Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.

UNC13B UNC13A

4.35e-06273222066784
Pubmed

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.

UNC13B UNC13A

4.35e-06273232187536
Pubmed

Munc13 proteins control regulated exocytosis in mast cells.

UNC13B UNC13D

4.35e-06273229141910
Pubmed

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

UNC13B UNC13A

4.35e-06273228772123
Pubmed

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

UNC13B UNC13A

4.35e-06273217267576
Pubmed

Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.

UNC13B UNC13A

4.35e-06273222814762
Pubmed

Overexpression of type I adenylyl cyclase in the forebrain impairs spatial memory in aged but not young mice.

ADCY1 ADCY8

4.35e-06273219726641
Pubmed

A role for calmodulin-stimulated adenylyl cyclases in cocaine sensitization.

ADCY1 ADCY8

4.35e-06273219244515
Pubmed

Different Munc13 isoforms function as priming factors in lytic granule release from murine cytotoxic T lymphocytes.

UNC13B UNC13D

4.35e-06273223590328
Pubmed

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.

UNC13B UNC13A

4.35e-06273228426965
Pubmed

Mouse Prickle1 and Prickle2 are expressed in postmitotic neurons and promote neurite outgrowth.

PRICKLE1 PRICKLE2

4.35e-06273217868671
Pubmed

A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.

UNC13B UNC13A

4.35e-06273235613050
Pubmed

Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs.

ADCY1 ADCY8

4.35e-06273236226826
Pubmed

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.

UNC13B UNC13A

4.35e-06273223770256
Pubmed

Membrane bridging by Munc13-1 is crucial for neurotransmitter release.

UNC13B UNC13A

4.35e-06273230816091
Pubmed

Distinct regional and subcellular localization of adenylyl cyclases type 1 and 8 in mouse brain.

ADCY1 ADCY8

4.35e-06273217335981
Pubmed

Role of Prickle1 and Prickle2 in neurite outgrowth in murine neuroblastoma cells.

PRICKLE1 PRICKLE2

4.35e-06273222218901
Pubmed

A common molecular basis for membrane docking and functional priming of synaptic vesicles.

UNC13B UNC13A

4.35e-06273219558619
Pubmed

Memory Retrieval Re-Activates Erk1/2 Signaling in the Same Set of CA1 Neurons Recruited During Conditioning.

ADCY1 ADCY8

4.35e-06273228366664
Pubmed

Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.

UNC13B UNC13A

4.35e-06273218701688
Pubmed

The type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acini.

ADCY1 ADCY8

4.35e-06273210799557
Pubmed

Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.

UNC13B UNC13A

4.35e-06273231851910
Pubmed

Spatiotemporal localization of the calcium-stimulated adenylate cyclases, AC1 and AC8, during mouse brain development.

ADCY1 ADCY8

4.35e-06273215844169
Pubmed

Calcium-stimulated adenylyl cyclases required for long-term potentiation in the anterior cingulate cortex.

ADCY1 ADCY8

4.35e-06273215985698
Pubmed

Identification and characterization of human PRICKLE1 and PRICKLE2 genes as well as mouse Prickle1 and Prickle2 genes homologous to Drosophila tissue polarity gene prickle.

PRICKLE1 PRICKLE2

4.35e-06273212525887
Pubmed

Adenylyl cylases 1 and 8 mediate select striatal-dependent behaviors and sensitivity to ethanol stimulation in the adolescent period following acute neonatal ethanol exposure.

ADCY1 ADCY8

4.35e-06273224769171
Pubmed

Mutations in prickle orthologs cause seizures in flies, mice, and humans.

PRICKLE1 PRICKLE2

4.35e-06273221276947
Pubmed

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.

UNC13B UNC13A

4.35e-06273211832228
Pubmed

Calcium activated adenylyl cyclase AC8 but not AC1 is required for prolonged behavioral anxiety.

ADCY1 ADCY8

4.35e-06273227234425
Pubmed

Munc13 controls the location and efficiency of dense-core vesicle release in neurons.

UNC13B UNC13A

4.35e-06273223229896
Pubmed

Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles.

ADCY1 ADCY8

4.35e-06273219029295
Pubmed

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.

UNC13B UNC13A

4.35e-06273211792326
Pubmed

Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence.

ADCY1 ADCY8

4.35e-06273219160506
Pubmed

Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition.

ADCY1 ADCY8

4.35e-06273225568126
Pubmed

Bidirectional synaptic plasticity and spatial memory flexibility require Ca2+-stimulated adenylyl cyclases.

ADCY1 ADCY8

4.35e-06273221752993
Pubmed

Ca2+-stimulated ADCY1 and ADCY8 regulate distinct aspects of synaptic and cognitive flexibility.

ADCY1 ADCY8

4.35e-06273237465213
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

MRE11 ING3 SLF2 ZFC3H1 RAD54L2 KIF2C

7.53e-0622273637071664
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CCDC88C HAUS6 HECW1 SACS COBLL1 TOGARAM1 ALPK1 ZFC3H1

9.24e-0649373815368895
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

UNC13B SRRM1 MYOM1 CLASP1 TOGARAM1 ZFC3H1 PHLDB2

1.11e-0536173726167880
Pubmed

Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity.

MAP2 PRICKLE1 ARID1A

1.15e-052173334011608
Pubmed

Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.

UNC13B UNC13A

1.30e-05373237343100
Pubmed

A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome.

PRICKLE1 PRICKLE2

1.30e-05373218976727
Pubmed

Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons.

ADCY1 ADCY8

1.30e-05373220837544
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13A

1.30e-05373223658173
Pubmed

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.

CLASP1 PHLDB2

1.30e-05373216824950
Pubmed

Calcium-mediated, purinergic stimulation and polarized localization of calcium-sensitive adenylyl cyclase isoforms in human airway epithelia.

ADCY1 ADCY8

1.30e-05373217586501
Pubmed

An increase in synaptic NMDA receptors in the insular cortex contributes to neuropathic pain.

ADCY1 ADCY8

1.30e-05373223674822
Pubmed

A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.

ADCY1 ADCY8

1.30e-0537328476432
Pubmed

Hippocampal neurons express a calcineurin-activated adenylyl cyclase.

ADCY1 ADCY8

1.30e-05373216251439
Pubmed

Calcium-dependent increases in protein kinase-A activity in mouse retinal ganglion cells are mediated by multiple adenylate cyclases.

ADCY1 ADCY8

1.30e-05373219924297
Pubmed

Prickle promotes neurite outgrowth via the Dishevelled dependent pathway in C1300 cells.

PRICKLE1 PRICKLE2

1.30e-05373219788910
Pubmed

Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.

UNC13B UNC13A

1.30e-05373217639022
Pubmed

Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation.

PRICKLE1 PRICKLE2

1.30e-05373222037766
Pubmed

Ca2+ -stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning.

ADCY1 ADCY8

1.30e-05373217196532
Pubmed

Ca-stimulated type 8 adenylyl cyclase is required for rapid acquisition of novel spatial information and for working/episodic-like memory.

ADCY1 ADCY8

1.30e-05373218448650
Pubmed

Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth.

ADCY1 ADCY8

1.30e-05373222649251
Pubmed

Developmental expression of PAM (protein associated with MYC) in the rodent brain.

ADCY1 ADCY8

1.30e-05373212036515
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13A

1.30e-05373233105896
Pubmed

Requirement for the RIIbeta isoform of PKA, but not calcium-stimulated adenylyl cyclase, in visual cortical plasticity.

ADCY1 ADCY8

1.30e-05373215483123
Pubmed

Discs large homolog 5 decreases formation and function of invadopodia in human hepatocellular carcinoma via Girdin and Tks5.

DLG5 SH3PXD2A

1.30e-05373228390157
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13A

1.30e-05373222966208
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13A

1.30e-05373215988013
Pubmed

Dysregulation of TrkB phosphorylation and proBDNF protein in adenylyl cyclase 1 and 8 knockout mice in a model of fetal alcohol spectrum disorder.

ADCY1 ADCY8

1.30e-05373226992697
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

MRE11 CRTC3 HAUS6 CLASP1 SH3PXD2A COBLL1 AMBRA1 STYXL2 CLOCK RASAL2 PHLDB2 KIF2C

1.85e-051321731227173435
Pubmed

Planar cell polarity-dependent asymmetric organization of microtubules for polarized positioning of the basal body in node cells.

PRICKLE1 PRICKLE2

2.60e-05473235420656
Pubmed

Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo.

UNC13B UNC13A

2.60e-05473210488064
Pubmed

Genetic evidence for the requirement of adenylyl cyclase 1 in synaptic scaling of forebrain cortical neurons.

ADCY1 ADCY8

2.60e-05473217650106
Pubmed

Phosphorylation of eukaryotic translation initiation factor 4E and eukaryotic translation initiation factor 4E-binding protein (4EBP) and their upstream signaling components undergo diurnal oscillation in the mouse hippocampus: implications for memory persistence.

ADCY1 ADCY8

2.60e-05473224895127
Pubmed

Coexistence of two forms of LTP in ACC provides a synaptic mechanism for the interactions between anxiety and chronic pain.

ADCY1 ADCY8

2.60e-05473225556835
Pubmed

Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium.

PRICKLE1 PRICKLE2

2.60e-05473236176272
Pubmed

Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.

UNC13B UNC13A

2.60e-05473219996097
Pubmed

Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing.

UNC13B UNC13A

2.60e-05473215123597
Pubmed

ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.

UNC13B UNC13A

2.60e-05473228264913
Pubmed

Towards complete sets of farnesylated and geranylgeranylated proteins.

PRICKLE1 PRICKLE2

2.60e-05473217411337
InteractionYWHAH interactions

CCDC88C SRRM1 DLG5 CRTC3 CLASP1 MAP2 SLF2 SH3PXD2A COBLL1 NR3C2 RFX7 CBL RNF115 RUBCN RASAL2 PHLDB2 KIF2C NIN

4.14e-0811027218int:YWHAH
InteractionSFN interactions

KIAA0408 CCDC88C SETD1A CRTC3 IGBP1 CLASP1 MAP2 SH3PXD2A COBLL1 CBL RNF115 RASAL2 PHLDB2

9.04e-076927213int:SFN
InteractionYWHAG interactions

KIAA0408 CCDC88C SRRM1 DLG5 CRTC3 CLASP1 MAP2 SH3PXD2A COBLL1 RFX7 C2orf49 CBL RNF115 RUBCN RASAL2 PHLDB2 KIF2C

1.37e-0612487217int:YWHAG
InteractionYWHAQ interactions

CCDC88C DLG5 CRTC3 CLASP1 MAP2 SH3PXD2A WWP1 COBLL1 NUMA1 RFX7 C2orf49 CBL RNF115 RASAL2 PHLDB2

7.72e-0611187215int:YWHAQ
InteractionYWHAZ interactions

CCDC88C DLG5 CRTC3 CLASP1 MAP2 SH3PXD2A COBLL1 MDH2 ARID1A C2orf49 CBL RNF115 RUBCN RASAL2 PHLDB2 NIN

1.30e-0513197216int:YWHAZ
InteractionDVL1 interactions

CCDC88C HECW1 PRICKLE1 WWP1 NUMA1 PRICKLE2

1.66e-05151726int:DVL1
InteractionCCDC57 interactions

KIAA0408 PTCHD3 MDM1 NUMA1 ZFC3H1 NIN

2.75e-05165726int:CCDC57
InteractionYEATS4 interactions

EPC2 HAUS6 ING3 NUMA1 SNX16 CLOCK

4.76e-05182726int:YEATS4
InteractionCEP135 interactions

CCDC88C DLG5 HAUS6 TOGARAM1 CCDC61 PHLDB2 NIN

5.26e-05272727int:CEP135
InteractionSOS1 interactions

SRRM1 PRICKLE1 SNX18 PRICKLE2 CBL

6.21e-05117725int:SOS1
InteractionCEP128 interactions

DLG5 HAUS6 ZFC3H1 CBL RASAL2 PHLDB2 NIN

9.14e-05297727int:CEP128
InteractionUSP9X interactions

SRRM1 IGBP1 PRICKLE1 WWP1 PRICKLE2 AMBRA1 MARCHF7 RNF115

1.28e-04422728int:USP9X
CytobandEnsembl 112 genes in cytogenetic band chr2q24

COBLL1 MARCHF7 CYTIP

1.12e-03127733chr2q24
Cytoband15q21.3

POLR2M RFX7

1.43e-033573215q21.3
GeneFamilyUNC13 homologs

UNC13B UNC13D UNC13A

4.32e-084413836
GeneFamilyPrickle planar cell polarity proteins|LIM domain containing

PRICKLE1 PRICKLE2

3.00e-0544121184
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY1 ADCY8

2.23e-041041253
GeneFamilySorting nexins|PX-BAR domain containing

SNX18 SNX16

1.96e-0329412754
GeneFamilyMAGE family

TRO MAGEB18

3.71e-03404121136
GeneFamilyLIM domain containing

PRICKLE1 PRICKLE2

7.91e-03594121218
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GAB4 RASAL2 PHLDB2

1.13e-02206413682
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4

SRRM1 EPC2 HAUS6 SLF2 TRO MDM1 MARCHF7

5.73e-06203727Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

SRRM1 EPC2 HAUS6 SLF2 TRO MDM1 MARCHF7 TOGARAM1 POLR2M RNF115

1.97e-055647210Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
ToppCellASK454-Endothelial-Lymphatic|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PIEZO2 NAPEPLD NID1 POLR2M CCDC61 PLPP6

4.98e-07179736fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 MAP2 ZNF804B ADCY1 ADCY8

6.80e-0616173569f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 MAP2 ZNF804B ADCY1 ADCY8

7.67e-061657356d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 MAP2 ZNF804B ADCY1 ADCY8

7.67e-0616573502cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 SACS PRICKLE1 TRO PRICKLE2

9.38e-06172735073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 COBLL1 ZNF804B CCDC168 PHLDB2

9.64e-061737358335b77f730ed43fc348a005566e73a103c6774b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLG5 COBLL1 ZNF804B CCDC168 PHLDB2

1.17e-05180735a407376209d80177bf7fc4200219030c83cb5f14
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAUS6 PRICKLE1 NID1 RASAL2 PHLDB2

1.20e-05181735fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

DLG5 COBLL1 NR3C2 ADCY1 PHLDB2

1.23e-05182735ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 GATM NID1 RASAL2 PHLDB2

1.27e-05183735709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 GATM NID1 RASAL2 PHLDB2

1.27e-05183735dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B COBLL1 NR3C2 ADCY8 CABLES1

1.40e-05187735db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NAPEPLD HECW1 COBLL1 NR3C2 CSMD2

1.72e-05195735787e95fb59c40bba784544b662fac37606ae1427
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 GATM NID1 RASAL2 PHLDB2

1.80e-05197735deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

PIEZO2 PRICKLE1 PRICKLE2 CSMD2 PHLDB2

1.80e-05197735f1c8936986123a3151140c374fcd62d6705c530b
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 GATM NID1 RASAL2 PHLDB2

1.80e-05197735a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

UNC13B KIAA0408 MAP2 UNC13D PHLDB2

1.85e-0519873575bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B CLASP1 PRICKLE2 AMBRA1 NR3C2

1.85e-051987351996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 GATM NID1 RASAL2 PHLDB2

1.85e-05198735f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal|6m / Sample Type, Dataset, Time_group, and Cell type.

KIAA0408 MAP2 TMEM151B ADCY1 UNC13A

1.94e-05200735cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCellCOVID-19_Severe-Neu_3|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

MAP2 TOGARAM1 CSMD2 ADCY8

5.00e-051237344c20c025b6f19f075a13282288fc537e6e186217
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ING3 NR3C2 ALPK1 PHLDB2

8.27e-051407340e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCellsevere_influenza-NK_CD56bright|World / disease group, cell group and cell class (v2)

OBSCN-AS1 CCDC168 CLOCK CABLES1

1.20e-04154734187b9d4eb0e98c506034735601ead480ff00bd57
ToppCellsevere_influenza-NK_CD56bright|severe_influenza / disease group, cell group and cell class (v2)

OBSCN-AS1 CCDC168 CLOCK CABLES1

1.29e-04157734fabaf54429dd5a899f9192f0d42522109ca36b9b
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYOM1 COBLL1 NID1 PHLDB2

1.52e-041647349eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYOM1 COBLL1 NID1 PHLDB2

1.52e-04164734f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYOM1 COBLL1 NID1 PHLDB2

1.52e-041647345c932a462cbf81d029c8d11ec3aea3191529527b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 GATM CSMD2 UNC13A

1.63e-041677343edb0570e583bb527165bcd8a4c25a042054043b
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

UNC13B DNHD1 STYXL2 OBSCN-AS1

1.71e-04169734dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

DNHD1 AMBRA1 RUBCN CYTIP

1.71e-041697346abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

COBLL1 NID1 C5orf47 RASAL2

1.75e-04170734d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

1.75e-0417073449fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

UNC13B MAP2 RASAL2 PHLDB2

1.75e-04170734e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

1.79e-041717349d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

UNC13B DNHD1 STYXL2 OBSCN-AS1

1.83e-04172734f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellCOVID-19_Mild-Neu_2|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

MRE11 WWP1 CLOCK PLPP6

1.83e-04172734f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCellIonocyte-iono-2|World / Class top

NAPEPLD MAP2 UNC13A CYTIP

1.87e-04173734e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PIEZO2 PTCHD3 NID1 POLR2M

1.87e-04173734a81992965137195d20fc498f750975303961a828
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 CCDC168 ADCY8 PHLDB2

1.87e-041737348ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

1.91e-04174734df5664da3b93c233509781429a9c6d7edf1b8944
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NAPEPLD COBLL1 CCDC168 PHLDB2

1.91e-04174734b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 CCDC168 ADCY8 PHLDB2

1.91e-04174734ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

1.95e-04175734d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 CCDC168 ADCY8 PHLDB2

2.00e-0417673440993c41c1017b53039a337174fc56632b278609
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

2.04e-04177734f902600c639087664316b3cf30cab243bc3d1c5c
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 MDM1 PRICKLE2 RASAL2

2.04e-041777348ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLG5 SACS NR3C2 CYTIP

2.08e-0417873451d2188406f04329311b2efd1108fc36617a860e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

2.08e-041787340e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 ZNF804B CCDC168 PHLDB2

2.13e-041797348766a5a066091879f521acfc612abf563ff78808
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 TMEM151B PRICKLE2 NID1

2.13e-04179734a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 MDM1 PRICKLE2 RASAL2

2.22e-041817344df7972f88117108698efd06b124b232f8588981
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS PRICKLE1 RAD54L2 CLOCK

2.22e-0418173441969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS PRICKLE1 RAD54L2 CLOCK

2.22e-041817343f50e61dc2a52d71a5801584617607e6246adcf2
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 MDM1 PRICKLE2 RASAL2

2.22e-04181734cbb530566893281289026bfd93adf721decd4ca3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 ZNF804B GATM ADCY8

2.27e-04182734e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 ZNF804B GATM ADCY8

2.27e-0418273457bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B MAP2 UNC13D PHLDB2

2.36e-0418473429c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MYOM1 MAP2 RASAL2

2.41e-0418573451dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

MAP2 COBLL1 RASAL2 PHLDB2

2.41e-0418573432b4e68e551d435a732f253f6ad83408c759a642
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 ALPK1 RUBCN PHLDB2

2.41e-0418573438486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MYOM1 MAP2 RASAL2

2.41e-04185734a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 ALPK1 RUBCN PHLDB2

2.41e-041857343c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

SLF2 SH3PXD2A PRICKLE2 ARID1A

2.46e-04186734de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYOM1 STYXL2 CSMD2 ADCY1

2.46e-041867344780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B NR3C2 ADCY8 CABLES1

2.46e-04186734bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SLF2 SH3PXD2A PRICKLE2 ARID1A

2.46e-041867340b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 COBLL1 ZNF804B RASAL2

2.51e-04187734a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2 COBLL1 ZNF804B RASAL2

2.51e-04187734c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

HECW1 TRO TMEM151B UNC13A

2.51e-0418773461b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

DLG5 SACS NR3C2 ADCY1

2.51e-04187734ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B MAP2 UNC13D PHLDB2

2.57e-04188734eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLASP1 SH3PXD2A COBLL1 NR3C2

2.57e-04188734bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLASP1 SH3PXD2A COBLL1 NR3C2

2.57e-04188734eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WWP1 GATM MPEG1 STYXL2

2.57e-04188734cb091912f9b627a78a8793a37df7f1de839f887f
ToppCellASK454-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

PIEZO2 NAPEPLD POLR2M PLPP6

2.62e-04189734316c857dec9383823e09f966bca62d52d933b141
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PRICKLE1 PRICKLE2 RASAL2

2.62e-0418973409dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

CCDC88C SNX18 MPEG1 CYTIP

2.62e-041897345c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B HECW1 PRICKLE1 NIN

2.62e-04189734a75226616340045b581d08429d2e123e041dee55
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B NR3C2 ADCY8 CABLES1

2.67e-041907348aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 PRICKLE1 PRICKLE2 RASAL2

2.67e-0419073452213cd2a6a20772d4f49ba9ac0407abafa528db
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

CCDC88C SNX18 CYTIP NIN

2.67e-04190734ed978cd5d9da87b49878a330e362762c487f849f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS SH3PXD2A COBLL1 NIN

2.67e-04190734ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP2 COBLL1 NID1 ADCY8

2.67e-041907347e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B COBLL1 ADCY8 CABLES1

2.67e-04190734625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP2 PRICKLE2 NR3C2 RASAL2

2.67e-04190734474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellMesenchymal_cells-Smooth_muscle|World / Lineage and Cell class

MYOM1 MAP2 STYXL2 RASAL2

2.67e-041907345aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B HECW1 PRICKLE1 NIN

2.67e-0419073449e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 PRICKLE1 PRICKLE2 RASAL2

2.72e-0419173438fe60a8570f3c6eb8e8f8646f90d505dfd7d647
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B NR3C2 ADCY8 CABLES1

2.72e-0419173434cc997e4e5c727495f321e6807a84aa124da486
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 SLF2 PRICKLE2 NID1

2.72e-04191734c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B COBLL1 NR3C2 ADCY8

2.72e-04191734a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 PRICKLE1 PRICKLE2 RASAL2

2.72e-041917340e6cd2628a5cebd35e960e4eb3b52ddc9358031c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 SLF2 PRICKLE2 NID1

2.72e-04191734806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 PRICKLE1 NID1 RASAL2

2.72e-04191734718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 SLF2 PRICKLE2 NID1

2.72e-04191734cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 PRICKLE1 NID1 RASAL2

2.72e-04191734454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MAP2 NID1 RASAL2

2.72e-041917347b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MAP2 NID1 RASAL2

2.72e-04191734cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYOM1 SH3PXD2A COBLL1 NID1

2.78e-04192734fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

UNC13B COBLL1 NR3C2 ADCY8

2.78e-0419273458c3737be7acce39fd2b91d70d6d7b2bbaa4f710
DiseaseColorectal Carcinoma

UNC13B MAP2 SACS NID1 NR3C2 ARID1A ADCY8 RASAL2 CABLES1

4.64e-05702719C0009402
Diseaseasthma, response to diisocyanate

SH3PXD2A PRICKLE2 POLR2M ADCY8 NIN

4.22e-04261715EFO_0006995, MONDO_0004979
Diseasemagnesium measurement

CCDC168 ALPK1 ADCY8

5.48e-0466713EFO_0004845
Diseaseepilepsy (implicated_via_orthology)

UNC13B PRICKLE1 PRICKLE2 UNC13A

6.54e-04163714DOID:1826 (implicated_via_orthology)
DiseaseRolandic epilepsy

PTCHD3 NR3C2

6.70e-0416712Orphanet_1945
Diseasemean platelet volume

SRRM1 HAUS6 NUMA1 NID1 UNC13D NR3C2 SNX16 CABLES1 NIN

7.41e-041020719EFO_0004584
Diseaseurinary albumin to creatinine ratio

MYOM1 NUMA1 GATM NR3C2

9.27e-04179714EFO_0007778
Diseasealcohol use disorder (implicated_via_orthology)

UNC13B ARID1A ADCY1 UNC13A

1.27e-03195714DOID:1574 (implicated_via_orthology)
Diseasesex interaction measurement, body mass index, age at assessment

COBLL1 ADCY8

1.40e-0323712EFO_0004340, EFO_0008007, EFO_0008343
Diseaselobe attachment

SACS POLR2M ADCY8 PHLDB2

1.58e-03207714EFO_0007667
Diseaseatrial fibrillation

SH3PXD2A POLR2M ALPK1 C5orf47 PHLDB2

2.02e-03371715EFO_0000275
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment

COBLL1 RFX7 CLOCK

2.10e-03105713EFO_0007788, EFO_0008007, EFO_0008343
DiseaseDevelopmental Disabilities

SETD1A CBL

2.38e-0330712C0008073

Protein segments in the cluster

PeptideGeneStartEntry
TTASTNVSASDRFAA

UNC13A

911

Q9UPW8
VSSSDRRNSGATFTE

ADCY8

606

P40145
SNAFRKLSNSSSSVS

C2orf49

136

Q9BVC5
SSSQTIDFSSNFSRT

EPC2

486

Q52LR7
IDFSSNFSRTNASSK

EPC2

491

Q52LR7
NRSSSVDSFRSRCSS

CCDC61

406

Q9Y6R9
SSSNSLFLAFRSDAS

CSMD2

1526

Q7Z408
RSSKSSFLNRSQVDS

DNHD1

2256

Q96M86
AAARESRQSSPSTNA

RAD54L2

1186

Q9Y4B4
NRLRSSTSSSSSDNQ

AMBRA1

751

Q9C0C7
SSQDSVNTSREFRSQ

COBLL1

646

Q53SF7
NFSTSSRSQDREALS

ALPK1

391

Q96QP1
LRASFLQDSQSSRSA

MPEG1

221

Q2M385
SASASSSSSSFAQQR

ARID1A

256

O14497
SRSARDQSFQHLSSF

NR3C2

536

P08235
AMANARSRTTSSSFS

MAGEB18

326

Q96M61
FQSTQAATASSRNSC

GATM

36

P50440
NRFASHTRFSSVDSA

HECW1

711

Q76N89
AALRRSFSTSAQNNA

MDH2

11

P40926
SRSASLSRAFSLASA

CCDC88C

1796

Q9P219
TQNASSSAADSRSGR

ING3

286

Q9NXR8
RDSSREASTSNSSRQ

IGBP1

221

P78318
RNTFQAVLASSDSSS

NID1

176

P14543
SARSAASSLRAFQTL

MDM1

686

Q8TC05
SASERSLSSFRSDAS

DLG5

886

Q8TDM6
NLSTASSRSQSNSED

RASAL2

806

Q9UJF2
RSTSRNFPSSDSEQA

KIAA0408

271

Q6ZU52
DSSDSAFQSARSRDS

PRICKLE1

316

Q96MT3
SSDSAFQNARAKESR

PRICKLE2

321

Q7Z3G6
TASEKLRNRSSFSTN

ADCY1

541

Q08828
AASASSQLRASRVQS

C5orf47

86

Q569G3
ARRNTIDSTSSFSQF

CABLES1

411

Q8TDN4
FRLTSALNRTNSDSA

CRTC3

151

Q6UUV7
ASQRAEHARSASFSQ

GAB4

221

Q2WGN9
SEDSSRGAFSRQTST

CYTIP

266

O60759
FSSRESESSRSNTQP

MARCHF7

226

Q9H992
SSTFFSRRSSQDSLN

MARCHF7

291

Q9H992
ASFLSQSVSSSDRNS

HAUS6

461

Q7Z4H7
ARRTLSDISNASSSF

CBL

786

P22681
ASSNARRVSSAESIN

CCDC168

3761

Q8NDH2
RVSSQAEDTSSSFDN

POLR2M

176

P0CAP2
TSSSSQFSSRDSAQL

RUBCN

566

Q92622
RNTASSSKSFVSSQS

RUBCN

601

Q92622
NADRASRRTFSTSAS

SACS

4371

Q9NZJ4
SRRTFSTSASRFQSD

SACS

4376

Q9NZJ4
RTSGQTFANSNSSRS

KIF2C

456

Q99661
RFSASRRSTEANFVS

PTCHD3

196

Q3KNS1
TASNSARAAERSSAL

NUMA1

1276

Q14980
RNVADSFSRTSRSCS

OBSCN-AS1

51

Q96MR7
RNKTCSSDSSNFTRF

TAS2R14

161

Q9NYV8
SSDSSNFTRFSSLIV

TAS2R14

166

Q9NYV8
DSTRQSQSTEASASN

RNF115

276

Q9Y4L5
SQSTEASASNRFSND

RNF115

281

Q9Y4L5
CQRAVSSSSIFSRSA

TMEM151B

436

Q8IW70
QSFDESGRRTTTSSA

NIN

271

Q8N4C6
ADIFNNSSRSLSSRS

SLF2

206

Q8IX21
ARALRSQSEESASAF

MRE11

526

P49959
SQSSASFFTPRSTRN

PHLDB2

526

Q86SQ0
QDAFSRRHFSASSAS

SETD1A

306

O15047
RRSSFSSQSINSQSV

CLOCK

476

O15516
QSDRSSSSSQESLNR

CLASP1

551

Q7Z460
SLRSTCSSHRFNGNS

ZNF804B

721

A4D1E1
ARSQNFRKSTTQASS

SARG

141

Q9BW04
DASTNVNFSRGASTR

TRO

716

Q12816
GVRRNSSFSTARSAA

SH3PXD2A

1011

Q5TCZ1
SSATVSRNLNRFSTF

SNX18

221

Q96RF0
ANGNSVRSTSRFSSS

STYXL2

996

Q5VZP5
RRQNQQSSSDSGSSS

SRRM1

486

Q8IYB3
TQSLTSCFARSSRSA

SOGA1

1381

O94964
SSSEPSQRSSFSSNR

PIEZO2

2101

Q9H5I5
SQRSSFSSNRSQRGS

PIEZO2

2106

Q9H5I5
FSSNRSQRGSTSTRN

PIEZO2

2111

Q9H5I5
TASTNVSASDRFAAS

UNC13B

836

O14795
GTNSSASSNFRCRSV

RFX7

1056

Q2KHR2
SRFEFQSLLSSRATA

PLPP6

36

Q8IY26
NSFSLNSSISSSARR

MAP2

1561

P11137
NTRSSSVSRDAFNSA

TOGARAM1

1451

Q9Y4F4
SNSRSSSAFEAAKSR

WWP1

316

Q9H0M0
ASSFTTNRNQRSSSF

SNX16

16

P57768
DNNSQIRSRSSSSSS

ZFC3H1

31

O60293
EAAASQRSSSLASNR

UNC13D

831

Q70J99
RESEAFRRASASSSQ

MYOM1

56

P52179
NSARNSGASDSSRFS

NAPEPLD

26

Q6IQ20