Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5B KDM5A KDM5C KDM5D	5.01e-09	6	87	4	GO:0034647
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5B KDM5A KDM5C KDM5D	2.32e-08	8	87	4	GO:0032453
GeneOntologyMolecularFunction	demethylase activity	KDM5B KDM5A KDM5C CYP51A1 KDM5D	1.33e-06	44	87	5	GO:0032451
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	4.10e-06	55	87	5	GO:0042974
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM5B KDM5A KDM5C KDM5D	6.35e-06	28	87	4	GO:0141052
GeneOntologyMolecularFunction	histone demethylase activity	KDM5B KDM5A KDM5C KDM5D	9.67e-06	31	87	4	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM5B KDM5A KDM5C KDM5D	1.10e-05	32	87	4	GO:0140457
GeneOntologyMolecularFunction	zinc ion binding	MMP25 PIAS4 KDM5B TRAF4 POLR1A KDM5A ZCCHC8 KDM5C ARIH2 ALB AGBL5 TRIM6 TRIM36 PNMA3	2.91e-05	891	87	14	GO:0008270
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.93e-05	82	87	5	GO:1990756
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	5.95e-05	95	87	5	GO:0140767
GeneOntologyMolecularFunction	nuclear receptor binding	PRAMEF14 PRAMEF17 KDM5D PRAMEF1 PRAMEF2 PRAMEF13	1.68e-04	187	87	6	GO:0016922
GeneOntologyMolecularFunction	transition metal ion binding	MMP25 PIAS4 KDM5B TRAF4 POLR1A KDM5A ZCCHC8 KDM5C ARIH2 CYP51A1 ALB AGBL5 TRIM6 TRIM36 PNMA3	1.77e-04	1189	87	15	GO:0046914
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	KDM5B KDM5A KDM5C KDM5D	1.86e-04	65	87	4	GO:0016706
GeneOntologyMolecularFunction	dioxygenase activity	KDM5B KDM5A KDM5C KDM5D	8.89e-04	98	87	4	GO:0051213
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	KDM5B KDM5A KDM5C CYP51A1 KDM5D	1.60e-03	194	87	5	GO:0016705
GeneOntologyMolecularFunction	pyridoxal phosphate binding	AGXT2 ALAS1 ALB	1.87e-03	56	87	3	GO:0030170
GeneOntologyMolecularFunction	vitamin B6 binding	AGXT2 ALAS1 ALB	1.97e-03	57	87	3	GO:0070279
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	KDM5C PRAMEF14 PRAMEF17 KDM5D PRAMEF1 PRAMEF2 PRAMEF13	2.29e-03	417	87	7	GO:0061629
GeneOntologyBiologicalProcess	oocyte development	PRAMEF14 CYP51A1 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	3.87e-06	99	87	6	GO:0048599
GeneOntologyBiologicalProcess	oocyte differentiation	PRAMEF14 CYP51A1 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	4.87e-06	103	87	6	GO:0009994
GeneOntologyBiologicalProcess	somatic stem cell population maintenance	PRAMEF14 SMO PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	6.41e-06	108	87	6	GO:0035019
GeneOntologyBiologicalProcess	blastocyst formation	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.97e-05	78	87	5	GO:0001825
GeneOntologyBiologicalProcess	oogenesis	PRAMEF14 CYP51A1 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	5.18e-05	156	87	6	GO:0048477
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.49e-06	47	87	5	GO:0031462
GeneOntologyCellularComponent	motile cilium	DNAH3 TTLL3 PRAMEF17 CFAP70 PRAMEF1 PRAMEF2 PRAMEF13 DNAH7	1.16e-04	355	87	8	GO:0031514
GeneOntologyCellularComponent	axonemal dynein complex	DNAH3 CFAP70 DNAH7	1.50e-04	25	87	3	GO:0005858
GeneOntologyCellularComponent	acrosomal vesicle	CYP51A1 PRAMEF17 PRAMEF1 TRIM36 PRAMEF2 PRAMEF13	2.21e-04	206	87	6	GO:0001669
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	PRAMEF14 ARIH2 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.59e-04	212	87	6	GO:0031461
GeneOntologyCellularComponent	inner dynein arm	DNAH3 DNAH7	7.54e-04	10	87	2	GO:0036156
GeneOntologyCellularComponent	SCAR complex	WASF3 CYFIP2	1.10e-03	12	87	2	GO:0031209
GeneOntologyCellularComponent	microfibril	MFAP5 LTBP1	1.30e-03	13	87	2	GO:0001527
GeneOntologyCellularComponent	dynein complex	DNAH3 CFAP70 DNAH7	1.48e-03	54	87	3	GO:0030286
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DNAH3 TTLL3 SYBU CFAP70 DNAH7 KLHL17	2.09e-03	317	87	6	GO:0032838
MousePheno	abnormal spermatogonia proliferation	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	3.30e-06	47	69	5	MP:0002685
MousePheno	abnormal jejunum morphology	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	4.80e-05	41	69	4	MP:0004002
MousePheno	abnormal cecum morphology	C20orf96 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.26e-04	99	69	5	MP:0000494
MousePheno	abnormal urinary bladder morphology	IPO7 ARIH2 ZFYVE26 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.10e-04	247	69	7	MP:0000538
MousePheno	abnormal sperm number	EXO5 SPEM2 ZCCHC8 PRAMEF14 AGPAT3 PRAMEF17 CFAP70 AGBL5 PRAMEF1 PRAMEF2 PRAMEF13	2.21e-04	624	69	11	MP:0002673
MousePheno	enlarged urinary bladder	ZFYVE26 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.66e-04	116	69	5	MP:0011874
MousePheno	decreased male germ cell number	EXO5 SPEM2 ZCCHC8 PRAMEF14 AGPAT3 PRAMEF17 CFAP70 AGBL5 PRAMEF1 PRAMEF2 PRAMEF13	2.75e-04	640	69	11	MP:0004901
MousePheno	abnormal duodenum morphology	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.76e-04	64	69	4	MP:0003271
MousePheno	increased circulating amylase level	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.99e-04	119	69	5	MP:0008806
MousePheno	fused first pharyngeal arch	PCSK6 SMO	3.56e-04	6	69	2	MP:0010335
Domain	Lys_sp_deMease-like_dom	KDM5B KDM5A KDM5C KDM5D	3.99e-10	4	85	4	IPR013637
Domain	PLU-1	KDM5B KDM5A KDM5C KDM5D	3.99e-10	4	85	4	PF08429
Domain	zf-C5HC2	KDM5B KDM5A KDM5C KDM5D	1.99e-09	5	85	4	PF02928
Domain	Znf_C5HC2	KDM5B KDM5A KDM5C KDM5D	1.99e-09	5	85	4	IPR004198
Domain	JmjN	KDM5B KDM5A KDM5C KDM5D	8.22e-08	10	85	4	SM00545
Domain	JMJN	KDM5B KDM5A KDM5C KDM5D	8.22e-08	10	85	4	PS51183
Domain	JmjN	KDM5B KDM5A KDM5C KDM5D	8.22e-08	10	85	4	PF02375
Domain	JmjN	KDM5B KDM5A KDM5C KDM5D	8.22e-08	10	85	4	IPR003349
Domain	-	KDM5B KDM5A KDM5C KDM5D	5.25e-07	15	85	4	1.10.150.60
Domain	BRIGHT	KDM5B KDM5A KDM5C KDM5D	5.25e-07	15	85	4	SM00501
Domain	ARID_dom	KDM5B KDM5A KDM5C KDM5D	5.25e-07	15	85	4	IPR001606
Domain	ARID	KDM5B KDM5A KDM5C KDM5D	5.25e-07	15	85	4	PS51011
Domain	ARID	KDM5B KDM5A KDM5C KDM5D	5.25e-07	15	85	4	PF01388
Domain	PRAME_family	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.47e-06	19	85	4	IPR026271
Domain	JmjC	KDM5B KDM5A KDM5C KDM5D	3.96e-06	24	85	4	PF02373
Domain	-	PIAS4 KDM5B TRAF4 KDM5A NSD2 KDM5C ARIH2 ZFYVE26 KDM5D TRIM6 TRIM36	5.91e-06	449	85	11	3.30.40.10
Domain	Znf_RING/FYVE/PHD	PIAS4 KDM5B TRAF4 KDM5A NSD2 KDM5C ARIH2 ZFYVE26 KDM5D TRIM6 TRIM36	7.27e-06	459	85	11	IPR013083
Domain	Zinc_finger_PHD-type_CS	KDM5B KDM5A NSD2 KDM5C KDM5D	1.16e-05	65	85	5	IPR019786
Domain	JMJC	KDM5B KDM5A KDM5C KDM5D	1.30e-05	32	85	4	PS51184
Domain	JmjC_dom	KDM5B KDM5A KDM5C KDM5D	1.30e-05	32	85	4	IPR003347
Domain	JmjC	KDM5B KDM5A KDM5C KDM5D	1.48e-05	33	85	4	SM00558
Domain	PHD	KDM5B KDM5A NSD2 KDM5C KDM5D	2.33e-05	75	85	5	PF00628
Domain	Znf_PHD-finger	KDM5B KDM5A NSD2 KDM5C KDM5D	3.00e-05	79	85	5	IPR019787
Domain	PHD	KDM5B KDM5A NSD2 KDM5C KDM5D	5.33e-05	89	85	5	SM00249
Domain	Znf_FYVE_PHD	KDM5B KDM5A NSD2 KDM5C ZFYVE26 KDM5D	5.63e-05	147	85	6	IPR011011
Domain	Znf_PHD	KDM5B KDM5A NSD2 KDM5C KDM5D	5.93e-05	91	85	5	IPR001965
Domain	ZF_PHD_2	KDM5B KDM5A NSD2 KDM5C KDM5D	7.28e-05	95	85	5	PS50016
Domain	ZF_PHD_1	KDM5B KDM5A NSD2 KDM5C KDM5D	7.66e-05	96	85	5	PS01359
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH7	1.80e-03	14	85	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH7	1.80e-03	14	85	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH7	1.80e-03	14	85	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH7	1.80e-03	14	85	2	PF08393
Domain	MT	DNAH3 DNAH7	1.80e-03	14	85	2	PF12777
Domain	AAA_8	DNAH3 DNAH7	1.80e-03	14	85	2	PF12780
Domain	ZnF_C2HC	ZCCHC8 ARIH2 PNMA3	2.01e-03	55	85	3	SM00343
Domain	Znf_CCHC	ZCCHC8 ARIH2 PNMA3	2.01e-03	55	85	3	IPR001878
Domain	DHC_fam	DNAH3 DNAH7	2.07e-03	15	85	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH7	2.07e-03	15	85	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH7	2.07e-03	15	85	2	PF03028
Domain	ATP_grasp_subdomain_1	TTLL3 CPS1	2.99e-03	18	85	2	IPR013815
Domain	-	FMOD LRRC24 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	3.45e-03	321	85	6	3.80.10.10
Domain	FRI	CORIN SMO	3.69e-03	20	85	2	SM00063
Domain	L_dom-like	FMOD LRRC24 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	3.83e-03	328	85	6	IPR032675
Domain	-	CORIN SMO	4.06e-03	21	85	2	1.10.2000.10
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM5B KDM5A KDM5C KDM5D	6.50e-06	29	60	4	MM14934
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM5B KDM5A KDM5C KDM5D	5.90e-05	50	60	4	M27232
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5B KDM5A KDM5C KDM5D	4.01e-11	4	89	4	16541399
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	8.17e-10	18	89	5	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	8.17e-10	18	89	5	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	8.17e-10	18	89	5	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	8.17e-10	18	89	5	14675769
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.11e-09	19	89	5	28604677
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.47e-09	20	89	5	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.47e-09	20	89	5	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.47e-09	20	89	5	21425410
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.49e-09	22	89	5	31729367
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	3.18e-09	23	89	5	19480014
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	5.00e-09	25	89	5	37451217
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	5.00e-09	25	89	5	12620990
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	6.17e-09	26	89	5	18500982
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	9.19e-09	28	89	5	25089626
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.33e-08	30	89	5	38786026
Pubmed	Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.	KDM5B KDM5A KDM5C	1.62e-08	3	89	3	26645689
Pubmed	Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.	KDM5B KDM5A KDM5C	1.62e-08	3	89	3	38230606
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.87e-08	32	89	5	37889087
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5B KDM5A KDM5C KDM5D	2.81e-08	13	89	4	24619213
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.99e-08	35	89	5	19389355
Pubmed	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.	KDM5B KDM5C KDM5D	6.47e-08	4	89	3	17320160
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	9.29e-08	17	89	4	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	9.29e-08	17	89	4	37781892
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.19e-07	18	89	4	39181896
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.24e-07	46	89	5	17287250
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.89e-07	50	89	5	31806660
Pubmed	Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.	KDM5B KDM5A KDM5C	3.22e-07	6	89	3	21960634
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	KDM5B NFATC2IP PRAMEF14 WNT6 SMO PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.47e-06	424	89	9	21731673
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5B KDM5A KDM5C KDM5D	1.55e-06	33	89	4	26864203
Pubmed	Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids.	AGPAT3 ALB	6.48e-06	2	89	2	32891885
Pubmed	Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B.	PIAS4 KDM5B	6.48e-06	2	89	2	34977006
Pubmed	Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C.	KDM5B KDM5C	6.48e-06	2	89	2	35468265
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	6.48e-06	2	89	2	10441747
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	6.48e-06	2	89	2	16416087
Pubmed	KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.	KDM5B KDM5A	6.48e-06	2	89	2	30472020
Pubmed	Functional analysis of corin protein domains required for PCSK6-mediated activation.	PCSK6 CORIN	6.48e-06	2	89	2	29180304
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	6.48e-06	2	89	2	32081420
Pubmed	KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance.	KDM5B KDM5A	6.48e-06	2	89	2	34184733
Pubmed	Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.	KDM5B KDM5A	6.48e-06	2	89	2	36509829
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	6.48e-06	2	89	2	9060413
Pubmed	PCSK6-mediated corin activation is essential for normal blood pressure.	PCSK6 CORIN	6.48e-06	2	89	2	26259032
Pubmed	KDM5 lysine demethylases are involved in maintenance of 3'UTR length.	KDM5B KDM5A	6.48e-06	2	89	2	28138513
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	6.48e-06	2	89	2	7524912
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM5B KDM5A KDM5C KDM5D	7.77e-06	49	89	4	34368113
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM5B KDM5A KDM5C KDM5D	1.43e-05	57	89	4	18022353
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.53e-05	58	89	4	31598710
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.64e-05	59	89	4	11279525
Pubmed	The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.	KDM5B KDM5A KDM5C	1.79e-05	20	89	3	23637629
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	1.94e-05	3	89	2	7544442
Pubmed	RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.	KDM5A KDM5C	1.94e-05	3	89	2	17320161
Pubmed	KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas.	KDM5A KDM5C	1.94e-05	3	89	2	37880235
Pubmed	Structural analysis of human KDM5B guides histone demethylase inhibitor development.	KDM5B KDM5C	1.94e-05	3	89	2	27214403
Pubmed	Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells.	KDM5B KDM5A	1.94e-05	3	89	2	16645588
Pubmed	Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.	AGXT2 ALB	1.94e-05	3	89	2	27752141
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM5B KDM5A KDM5C	2.08e-05	21	89	3	27626377
Pubmed	Studies on the biological functions of CPS1 in AFB1 induced hepatocarcinogenesis.	ALB CPS1	3.87e-05	4	89	2	27425868
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5C KDM5D	3.87e-05	4	89	2	32732223
Pubmed	A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.	KDM5C KDM5D	3.87e-05	4	89	2	7951230
Pubmed	H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence.	KDM5B KDM5A	3.87e-05	4	89	2	22615382
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PRAMEF14 SMO PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13 KLHL17	4.21e-05	363	89	7	14691545
Pubmed	MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.	KDM5B KDM5C	6.44e-05	5	89	2	26621457
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PCED1A TTLL3 ARHGEF1 PRAMEF14 AGPAT3 LTBP1 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13 KIF24 CYFIP2	7.67e-05	1242	89	12	30973865
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	IPO7 PRAMEF14 ALB PRAMEF17 HAL PRAMEF1 PRAMEF2 PRAMEF13	1.02e-04	564	89	8	21565611
Pubmed	Immunohistochemical analysis of development of desmin-positive hepatic stellate cells in mouse liver.	ALB CPS1	1.35e-04	7	89	2	11197537
Pubmed	Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.	KDM5B KDM5C	1.35e-04	7	89	2	28262558
Pubmed	DNA-binding properties of ARID family proteins.	KDM5B KDM5A	1.35e-04	7	89	2	15640446
Pubmed	ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function.	ALB ZBTB7B	1.79e-04	8	89	2	38225233
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KDM5B KDM5A KDM5C	1.99e-04	44	89	3	24183668
Pubmed	Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.	WASF3 CYFIP2	2.30e-04	9	89	2	38981622
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	FAM171A1 EXO5 SPATA6L POLR1A KRT32 KRT222 RICTOR ZFYVE26 EVI5L	2.83e-04	832	89	9	36724073
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	DNAH3 ELP5 SYBU SRRM2 DNAH7	3.40e-04	233	89	5	37704626
Pubmed	A dual-color FISH gene map of the proximal region of rat Chromosome 4 and comparative analysis in human and mouse.	CYP51A1 SMO	3.51e-04	11	89	2	11707776
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	FAM171A1 IPO7 ELP5 NSD2 RICTOR LTBP1 TRIM36 SRRM2 CYFIP2 ITPR3	3.52e-04	1049	89	10	27880917
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	CORO1A INTS6 NSD2 ZCCHC8 ARHGEF1 FMNL1	3.85e-04	370	89	6	22922362
Pubmed	Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.	KDM5C KDM5D	4.96e-04	13	89	2	14660691
Pubmed	Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.	NSD2 ARHGEF1 OCRL CYFIP2	5.10e-04	143	89	4	32560809
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	INTS6 PNPLA6 KDM5A NSD2 ZCCHC8 KDM5C PCSK6 RICTOR SRRM2 EVI5L	5.70e-04	1116	89	10	31753913
Pubmed	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	SLC6A13 CPS1	5.78e-04	14	89	2	23378610
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH7	5.78e-04	14	89	2	9373155
Pubmed	Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells.	ALB CPS1	5.78e-04	14	89	2	26724533
Pubmed	New loci associated with kidney function and chronic kidney disease.	SLC6A13 KDM5A CPS1	6.60e-04	66	89	3	20383146
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	KDM5C KDM5D	6.65e-04	15	89	2	14762062
Pubmed	Maternal microRNAs are essential for mouse zygotic development.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	6.97e-04	273	89	5	17369397
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KDM5B KDM5A KDM5C KDM5D	7.24e-04	157	89	4	30186101
Pubmed	Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.	ALB CPS1	7.59e-04	16	89	2	19185577
Pubmed	Identification and characterization of proteins interacting with Traf4, an enigmatic p53 target.	TRAF4 SARDH	7.59e-04	16	89	2	16969126
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	KDM5C KDM5D	9.65e-04	18	89	2	12023983
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	KDM5B MOV10	9.65e-04	18	89	2	25363768
Pubmed	TRIM6 facilitates SARS-CoV-2 proliferation by catalyzing the K29-typed ubiquitination of NP to enhance the ability to bind viral genomes.	ALB TRIM6	1.08e-03	19	89	2	38515377
Pubmed	Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.	SMO ALB	1.08e-03	19	89	2	34433966
Pubmed	Identification of Protor as a novel Rictor-binding component of mTOR complex-2.	RICTOR CPS1	1.19e-03	20	89	2	17461779
Pubmed	A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis.	WNT6 PCSK6 ITPR3	1.24e-03	82	89	3	30728831
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	HAL CPS1	1.32e-03	21	89	2	27088858
Pubmed	Temporomandibular joint formation requires two distinct hedgehog-dependent steps.	WNT6 SMO	1.32e-03	21	89	2	19815519
Pubmed	Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.	WASF3 ECEL1	1.45e-03	22	89	2	29449449
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	POLR1A IPO7 NSD2 ZCCHC8 SRRM2 MOV10 ITPR3	1.45e-03	653	89	7	22586326
Pubmed	Quantitative interaction proteomics of neurodegenerative disease proteins.	KDM5B IPO7 CYP51A1 VPS28 MOV10	1.47e-03	323	89	5	25959826
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.53e-03	326	89	5	17015433
Pubmed	Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice.	ALB CPS1	1.58e-03	23	89	2	23386589
Cytoband	1p36.21	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.57e-07	63	89	5	1p36.21
Cytoband	20p13	PCED1A C20orf96 C20orf141	1.05e-03	102	89	3	20p13
Cytoband	Ensembl 112 genes in cytogenetic band chr20p13	PCED1A C20orf96 C20orf141	1.80e-03	123	89	3	chr20p13
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13 KLHL17	2.14e-03	681	89	6	chr1p36
GeneFamily	PRAME family	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	1.16e-08	24	58	5	686
GeneFamily	AT-rich interaction domain containing	KDM5B KDM5A KDM5C KDM5D	1.27e-07	15	58	4	418
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5B KDM5A KDM5C KDM5D	9.66e-07	24	58	4	485
GeneFamily	PHD finger proteins	KDM5B KDM5A NSD2 KDM5C KDM5D	1.02e-05	90	58	5	88
GeneFamily	Exonucleases	EXO5 PAN2	1.18e-03	16	58	2	544
GeneFamily	Dyneins, axonemal	DNAH3 DNAH7	1.33e-03	17	58	2	536
Coexpression	KINNEY_DNMT1_METHYLATION_TARGETS	PRAMEF17 HAL PRAMEF1 PRAMEF2 PRAMEF13	1.04e-07	34	89	5	MM955
Coexpression	KOHOUTEK_CCNT2_TARGETS	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	8.42e-06	81	89	5	MM938
Coexpression	MORI_SMALL_PRE_BII_LYMPHOCYTE_UP	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.13e-05	98	89	5	MM592
Coexpression	HUANG_GATA2_TARGETS_DN	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	2.13e-05	98	89	5	MM942
Coexpression	BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS	PRAMEF14 PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13 MOV10	3.50e-05	180	89	6	MM612
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED	PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	4.28e-05	57	89	4	MM1262
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	PIAS4 PCED1A CDAN1 PNPLA6 TTLL3 NFATC2IP PAN2 ZFYVE26 KDM5D SRRM2 PNMA3 ITPR3	5.51e-05	905	89	12	M40865
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	PIAS4 PCED1A CDAN1 PNPLA6 TTLL3 NFATC2IP PAN2 SRRM2 PNMA3 ITPR3	5.84e-05	634	89	10	M40866
Coexpression	GSE17721_LPS_VS_POLYIC_6H_BMDC_DN	CORO1A INTS6 ARHGEF1 FMNL1 LACTB ITPR3	6.11e-05	199	89	6	M3809
Coexpression	YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN	SLC22A9 PRAMEF14 SMO PRAMEF17 PRAMEF1 PRAMEF2 PRAMEF13	8.92e-05	309	89	7	MM1244
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SPATA6L CFAP70 MYCBPAP CCDC191 DNAH7	1.15e-06	169	89	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SPATA6L CFAP70 MYCBPAP CCDC191 DNAH7	1.32e-06	173	89	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	(12)_SLC16A7+\|World / shred by cell type by condition	C20orf96 SLC22A9 MFAP5 DNAH3 CFAP70 DNAH7	2.35e-06	191	89	6	e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SPATA6L CFAP70 MYCBPAP CCDC191 DNAH7	2.81e-06	197	89	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Dcn-Endothelial_Tip.Dcn.Nenf_(Nenf)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6 HAL	3.35e-06	114	89	5	7be16e7f7b9c9dbd68933ace3b7f8f661bed41a7
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Dcn\|Thalamus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6 HAL	3.35e-06	114	89	5	f4bdfc47418d22a49e0c4a6c3bd0663e15fb53bb
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	MMP25 MFAP5 SLC6A13 FMOD WNT6	1.40e-05	153	89	5	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	MMP25 MFAP5 SLC6A13 FMOD WNT6	1.40e-05	153	89	5	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	MMP25 MFAP5 SLC6A13 FMOD WNT6	1.40e-05	153	89	5	2513edfae62a44e51d3556675a096723194c966c
ToppCell	droplet-Fat-Bat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO5 OCRL HAL KDM5D TRIM6	2.20e-05	168	89	5	6fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell	droplet-Fat-Bat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO5 OCRL HAL KDM5D TRIM6	2.20e-05	168	89	5	794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCell	droplet-Fat-Bat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO5 OCRL HAL KDM5D TRIM6	2.20e-05	168	89	5	1e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	PNPLA6 ALAS1 LTBP1 HAL MOV10	2.33e-05	170	89	5	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	PCSK6 ALB HAL SARDH CPS1	2.61e-05	174	89	5	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6 SMO	3.40e-05	184	89	5	235890e8b424f4386b6ea52d173d20a00898df73
ToppCell	wk_15-18-Hematologic-Myeloid-Myelocyte-like\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MMP25 CORO1A ALB HAL FMNL1	3.49e-05	185	89	5	92b9ec18ff7c53a52b87e2c2012d0b719a7ad20a
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B ARHGEF1 ALB ZBTB7B FMNL1	3.49e-05	185	89	5	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B ARHGEF1 ALB ZBTB7B FMNL1	3.49e-05	185	89	5	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	C20orf96 DNAH3 TTLL3 CFAP70 CCDC191	3.77e-05	188	89	5	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 C10orf105	3.97e-05	95	89	4	3699ea16660a22ea79fecfea56ece2dfb0f13467
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 C10orf105	3.97e-05	95	89	4	cbfe615d880913bafaf5e7e8d24c3ec14a9351ce
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 C10orf105	3.97e-05	95	89	4	27ac23b87747434a3084cc087e7b884e68f0eab9
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP5 PCSK6 WASF3 SMO LTBP1	4.07e-05	191	89	5	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C20orf96 DNAH3 TTLL3 CFAP70 MYCBPAP	4.17e-05	192	89	5	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC22A9 PCSK6 SYBU SARDH CYFIP2	4.17e-05	192	89	5	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	C20orf96 DNAH3 CFAP70 CCDC191 DNAH7	4.38e-05	194	89	5	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C20orf96 DNAH3 SPATA6L CFAP70 DNAH7	4.38e-05	194	89	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SPATA6L CFAP70 CCDC191 DNAH7	4.38e-05	194	89	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGAP42 DNAH3 SPATA6L CFAP70 DNAH7	4.49e-05	195	89	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ARHGAP42 DNAH3 SPATA6L CFAP70 DNAH7	4.49e-05	195	89	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGAP42 DNAH3 SPATA6L CFAP70 DNAH7	4.49e-05	195	89	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	C20orf96 DNAH3 SPATA6L CFAP70 DNAH7	4.49e-05	195	89	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 SPATA6L CFAP70 DNAH7 KIF24	4.49e-05	195	89	5	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C20orf96 DNAH3 SPATA6L CFAP70 DNAH7	4.60e-05	196	89	5	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	ARHGAP42 DNAH3 SPATA6L CFAP70 DNAH7	4.60e-05	196	89	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C20orf96 DNAH3 CFAP70 CCDC191 DNAH7	4.71e-05	197	89	5	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FMOD ECEL1 LTBP1 AGBL5 CYFIP2	5.06e-05	200	89	5	a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	5.45e-05	103	89	4	39d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	5.45e-05	103	89	4	01a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C20orf141 SLC6A13 FMOD WNT6	6.55e-05	108	89	4	db82e0273ce10627462ff0402f4c1d4c9cb3875b
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C20orf141 SLC6A13 FMOD WNT6	6.55e-05	108	89	4	2a00a9d3c9ef0c9c743939ee6e79ccbd401eccf7
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C20orf141 SLC6A13 FMOD WNT6	6.55e-05	108	89	4	0c8bac6c520a3600765327c44705675927bc2f60
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	1.19e-04	126	89	4	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	1.19e-04	126	89	4	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	1.19e-04	126	89	4	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	1.19e-04	126	89	4	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	1.19e-04	126	89	4	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	droplet-Heart-HEART-1m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM1 REPS2 TRIM36 MOV10	1.23e-04	127	89	4	983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	1.42e-04	132	89	4	560e836764ed7806fb18282dfebe434d30112a9a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCED1A EXO5 NSD2 ZFYVE26	1.42e-04	132	89	4	4152529611eeacf0c547e2a134d5b98c45426b13
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 ITPR3	1.55e-04	135	89	4	7e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 ITPR3	1.55e-04	135	89	4	4cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 ITPR3	1.55e-04	135	89	4	6bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD WNT6 ITPR3	1.55e-04	135	89	4	97989546826bf3739e1b86a10832a457fd37c5d2
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD KDM5A WNT6	1.89e-04	142	89	4	6a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD KDM5A WNT6	1.89e-04	142	89	4	671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD KDM5A WNT6	1.89e-04	142	89	4	3557084150670fd2e2634fc674f228ab85181b59
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC6A13 FMOD KDM5A WNT6	1.89e-04	142	89	4	a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PCSK6 ECEL1 CFAP70 DNAH7	2.27e-04	149	89	4	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PCSK6 ECEL1 CFAP70 DNAH7	2.27e-04	149	89	4	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	2.51e-04	153	89	4	151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MFAP5 SLC6A13 WNT6 MYCBPAP	2.57e-04	154	89	4	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	facs-Heart-RA-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AGXT2 SLC6A13 CORO1A CYFIP2	2.63e-04	155	89	4	cc3fc379ea78742a216317054f336331f7c7a157
ToppCell	facs-Heart-RA-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AGXT2 SLC6A13 CORO1A CYFIP2	2.63e-04	155	89	4	1900a76754e2a9c7117e531c5907b7942f72c4a6
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 PCSK6 SARDH CPS1	2.70e-04	156	89	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	PBMC-Mild-cDC_6\|Mild / Compartment, Disease Groups and Clusters	SHROOM1 LTBP1 CPS1 KIF24	2.70e-04	156	89	4	3db686849844120b3e376599929d11ad06f0d577
ToppCell	droplet-Liver-nan-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALB HAL SARDH CPS1	2.77e-04	157	89	4	b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 CFAP70 DNAH7 KIF24	2.77e-04	157	89	4	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP25 CORO1A FMNL1 CYFIP2	2.83e-04	158	89	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP25 CORO1A FMNL1 CYFIP2	2.97e-04	160	89	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 NFATC2IP RICTOR CCDC191	2.97e-04	160	89	4	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MMP25 CORO1A ZFYVE26 FMNL1	3.04e-04	161	89	4	5a8698790f9aba796dd2b64af419055c60bd7de8
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDAN1 C20orf96 PCSK6 EVI5L	3.19e-04	163	89	4	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL3 NFATC2IP AGBL5 FMNL1	3.19e-04	163	89	4	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C20orf96 TTLL3 CFAP70 KIF24	3.26e-04	164	89	4	d9531848105d606adedde65426177cf851140e31
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	3.34e-04	165	89	4	570483b43ccb5831feec9337b4664814431d40b1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	3.34e-04	165	89	4	2026a9a07f4d314cc05c167e491312b373468e46
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	DNAH3 CFAP70 MYCBPAP DNAH7	3.50e-04	167	89	4	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF1 WNT6 FMNL1 CYFIP2	3.58e-04	168	89	4	d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MFAP5 SLC6A13 FMOD WNT6	3.58e-04	168	89	4	26aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF1 WNT6 FMNL1 CYFIP2	3.58e-04	168	89	4	f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 CFAP70 MYCBPAP DNAH7	3.66e-04	169	89	4	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1-Inhibitory_Gad1Gad2_Htr3a.Phlda1_(Interneuron,__(candidate_CGE-derived_3))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CORIN ECEL1 CPS1	3.72e-04	70	89	3	0f1dba07a2cd974a25239ae1728cfb007a37954c
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CORIN ECEL1 CPS1	3.72e-04	70	89	3	c579fd093d30a5ee56f7cf1039120d00a6369649
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1-Inhibitory_Gad1Gad2_Htr3a.Phlda1_(Interneuron,__(candidate_CGE-derived_3))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CORIN ECEL1 CPS1	3.72e-04	70	89	3	511ca39208a8a0efd24cca47270083d5024e6972
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP25 SLC6A13 CORO1A TRIM36	3.74e-04	170	89	4	2b5b1f8d13b9806b76b44a53f47a23dd9ff09808
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP25 SLC6A13 CORO1A TRIM36	3.74e-04	170	89	4	43c48267d8291c88263148a36fbb63c27f0e4f1c
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO1A HAL TRIM6 FMNL1	3.82e-04	171	89	4	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CDAN1 C20orf96 PCSK6 EVI5L	3.91e-04	172	89	4	da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO1A ARHGEF1 FMNL1 CYFIP2	3.91e-04	172	89	4	f45489e80c59b824846ffda675de0d118a8b850c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C20orf96 C10orf105 CFAP70 MYCBPAP	4.00e-04	173	89	4	a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C20orf96 C10orf105 CFAP70 MYCBPAP	4.00e-04	173	89	4	e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CORO1A TRAF4 LRRC24 FMNL1	4.08e-04	174	89	4	4120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	FMOD WASF3 CORIN LTBP1	4.17e-04	175	89	4	fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDAN1 CORIN AGBL5 EVI5L	4.26e-04	176	89	4	4ed73c73972334f6dc4229920205547823252fa0
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ALB HAL SARDH CPS1	4.26e-04	176	89	4	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C20orf96 C10orf105 CFAP70 MYCBPAP	4.36e-04	177	89	4	ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TTLL3 WNT6 EVI5L	4.36e-04	177	89	4	291231b1520c135e92739e201495fe1935efa927
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 CFAP70 MYCBPAP DNAH7	4.36e-04	177	89	4	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C20orf96 C10orf105 CFAP70 MYCBPAP	4.36e-04	177	89	4	bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
Computational	Genes in the cancer module 430.	CORO1A TTLL3 ARHGEF1 CYFIP2	1.01e-04	55	48	4	MODULE_430
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	5.27e-11	4	81	4	DOID:0060809 (implicated_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	9.35e-08	16	81	4	DOID:0050888 (implicated_via_orthology)
Disease	urinary metabolite measurement	MMP25 AGXT2 SLC6A13 RICTOR HAL CPS1 LACTB	5.15e-06	245	81	7	EFO_0005116
Disease	X-25420 measurement	SLC6A13 CPS1	2.23e-05	3	81	2	EFO_0800926
Disease	beta-aminoisobutyric acid measurement	AGXT2 SLC6A13 KDM5A	3.87e-05	24	81	3	EFO_0010464
Disease	intellectual disability (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	5.52e-05	75	81	4	DOID:1059 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D ITPR3	6.35e-05	152	81	5	DOID:0060041 (implicated_via_orthology)
Disease	matrilysin measurement	ARHGAP42 MMP25	7.40e-05	5	81	2	EFO_0008227
Disease	alcohol use disorder (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D SRRM2	2.04e-04	195	81	5	DOID:1574 (implicated_via_orthology)
Disease	handedness	ARHGEF1 PCSK6 WASF3 TRIM36	2.12e-04	106	81	4	EFO_0009902
Disease	1-ribosyl-imidazoleacetate measurement	SLC6A13 CPS1	2.65e-04	9	81	2	EFO_0800034
Disease	3-aminoisobutyrate measurement	AGXT2 SLC6A13	4.83e-04	12	81	2	EFO_0010980
Disease	colon cancer (is_marker_for)	KDM5C RICTOR SMO	5.80e-04	59	81	3	DOID:219 (is_marker_for)
Disease	serum homoarginine measurement	AGXT2 CPS1	1.37e-03	20	81	2	EFO_0005421
Disease	hepatocellular carcinoma (is_marker_for)	KDM5C RICTOR ALB SARDH CPS1	1.45e-03	301	81	5	DOID:684 (is_marker_for)
Disease	mean arterial pressure, alcohol drinking	ARHGAP42 TRIM36 MOV10	2.51e-03	98	81	3	EFO_0004329, EFO_0006340

Protein segments in the cluster

Peptide	Gene	Start	Entry
EMVQDKISCRPLPRE	AGXT2	441	Q9BYV1
RMPCIKTRLQARPRL	AGBL5	776	Q8NDL9
MSSPCEKLIRRDIAR	EVI5L	146	Q96CN4
RPRCRRLQLKDMIPT	ARHGEF1	546	Q92888
LPRLVRPEVDVMCTA	ALB	136	P02768
ADCPMVIRVQEPRAR	ARIH2	231	O95376
HERRCEPIAMTVPRK	CORO1A	341	P31146
PPGCRSLQEEREMLR	CDAN1	241	Q8IWY9
QGIPKRRRCMSPLLR	INTS6	651	Q9UL03
RPIRLMLGTCPTKED	ITPR3	411	Q14573
MPREVARDPQLCEKL	ASB8	226	Q9H765
ELKTRRRPMLPLEAQ	EXO5	196	Q9H790
TVATMRKPRCSLPDV	MMP25	81	Q9NPA2
RRAPPVDAEILRTMK	PAN2	421	Q504Q3
MEEEKSILRQRRCLP	PNPLA6	1351	Q8IY17
EDVLLRRPKCTPDMD	C20orf96	336	Q9NUD7
RRPKCTPDMDVILNI	C20orf96	341	Q9NUD7
PEKEQLLDRRPTECM	FAM171A1	526	Q5VUB5
KRSAMPADAPLCLRL	FMOD	356	Q06828
ELMCTLREVRQPKRI	PRAMEF17	436	Q5VTA0
MESVVRRCPFLSRVP	ALAS1	1	P13196
APPVDLTRVLEEMRC	KRT32	256	Q14532
RVPCKPETVMRIASI	LACTB	151	P83111
CPLCMRSRRPRLETI	KDM5D	1231	Q9BY66
MCVAASDKRPRSIPL	PCSK6	501	P29122
TRRCLIDDREMPVKV	IPO7	501	O95373
PDIEVRLIMRRSCSI	KRT222	271	Q8N1A0
RLIMRRSCSIPSIKP	KRT222	276	Q8N1A0
PMVLDASEKRCIRPA	LTBP1	1496	Q14766
MVFCLSSEEPRRPLR	PCED1A	1	Q9H1Q7
NPKSVREECIPMKRR	NSD2	386	O96028
VCVRKRPLGMREVRR	KIF24	226	Q5T7B8
LLTSRDRKIMCAEPP	LRRC24	226	Q50LG9
DRKIMCAEPPRLALQ	LRRC24	231	Q50LG9
LRRRMGCPTPKCENE	KDM5B	256	Q9UGL1
MAAPEPLRPRLCRLV	SLC9A3R2	1	Q15599
LIEVMPKICRLPRHE	CYFIP2	976	Q96F07
IPDDTPMCRILLRKE	RICTOR	1601	Q6R327
SCLDMREIERLGPRP	ECEL1	186	O95672
LCPLCMRSRRPRLET	KDM5A	1211	P29375
KDELCRQMAGLPPRR	MFAP5	136	Q13361
VAEDKLLRFPMRSCP	ACP4	146	Q9BZG2
PRLRDADPILRCEMA	CPS1	1316	P31327
PLSPERCRMLLALRI	HAL	201	P42357
RQHVPRLMKCVRLPL	KLHL17	271	Q6TDP4
LRCLRPDKMVPAVRE	DNAH3	3476	Q8TD57
ALVPKRMPEELARRV	CFAP70	476	Q5T0N1
LLSKPREEEPRTCQM	CCDC191	606	Q8NCU4
RCIKETLRLRPPIMI	CYP51A1	371	Q16850
RMLIIRCLRPDKVIP	DNAH7	3381	Q8WXX0
MTRLCLPRPEAREDP	C20orf141	1	Q9NUB4
MKQSPALAPEERCRR	CORIN	1	Q9Y5Q5
LCFSRIPRLPERMTT	FMNL1	786	O95466
ALRAMCKRTDPVPVT	ELP5	106	Q8TE02
TPLRAELMCTLREVR	PRAMEF13	431	Q5VWM6
ELMCTLREVRQPKRI	PRAMEF13	436	Q5VWM6
LDCQLEKLPMRPRDR	STEEP1	41	Q9H5V9
KLTPSHPRRCREVLM	SPATA6L	96	Q8N4H0
RPKILMCPEHETERI	TRIM36	206	Q9NQ86
KCLRPEDILRFMETR	POLR1A	1331	O95602
MKDIPRTPSRGRSEC	SRRM2	1466	Q9UQ35
LLPRMSVSQDPRKLC	SPATA31C2	836	B4DYI2
PSRDIRMVPEDIKPC	MOV10	581	Q9HCE1
ELMCTLREVRQPKRI	PRAMEF14	436	Q5SWL7
NPDLPPKMCRRLRLD	ARHGAP42	771	A6NI28
SIPLDSNMRPEKCRR	SLC22A9	76	Q8IVM8
VPEGEKRRRLMECLR	PNMA3	196	Q9UL41
LIPLAEVRAAMRPAC	SHROOM1	576	Q2M3G4
TPLRAELMCTLREVR	PRAMEF1	431	O95521
ELMCTLREVRQPKRI	PRAMEF1	436	O95521
ELMCTLREFRQPKRI	PRAMEF2	436	O60811
CRADLVRLPLRMSEP	NFATC2IP	271	Q8NCF5
ALCRMKRPIREVPVT	OCRL	686	Q01968
LRRRLVCFTMEDKVP	SARDH	821	Q9UL12
MTLCKPAALDPSRRR	C10orf105	56	Q8TEF2
DCPMPRNAARISEKR	ZCCHC8	241	Q6NZY4
LVRKRRSQMPQECPV	ZBTB7B	336	O15156
CKARRTMRPLPRRIE	TYMSOS	51	Q8TAI1
ADMCVRRFPLEDIPL	AGPAT3	251	Q9NRZ7
RIESIKCELPLPRFM	REPS2	126	Q8NFH8
LSPELRCMPKRVEAR	SPEM2	236	Q0P670
RCMPKRVEARSELRL	SPEM2	241	Q0P670
PSSPREKDLLSMLCR	SYBU	196	Q9NX95
LKGPFRERIRQLMCP	SLC6A13	556	Q9NSD5
MPLVKRNIEPRHLCR	WASF3	1	Q9UPY6
LDCPLAMERIKEDRP	VPS28	101	Q9UK41
SPLVMDPTSICRKAR	WNT6	31	Q9Y6F9
MDPRRKVCHLVARPA	MYCBPAP	101	Q8TBZ2
IPCPNRCPMKLSRRD	TRAF4	111	Q9BUZ4
RCPMKLSRRDLPAHL	TRAF4	116	Q9BUZ4
KPRAEACPMKRLSPL	TTLL3	686	Q9Y4R7
MPKCENDRVELPSRT	SMO	131	Q99835
CPLVKMRLSVPCRAE	PIAS4	326	Q8N2W9
SMCTELSIPLARKRP	TBC1D19	111	Q8N5T2
KALQLLRRIPDPTMC	ZFYVE26	1596	Q68DK2
PDLKRMLRVCRELTD	TRIM6	281	Q9C030
KFLCPLCMRSRRPRL	KDM5C	1241	P41229