Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	4.18e-16	27	123	10	GO:0033038
GeneOntologyMolecularFunction	taste receptor activity	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	4.45e-15	33	123	10	GO:0008527
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	LPAR3 HCAR2 HTR5A AXL LPAR1 CCKBR LYVE1 CD14 IL17RE TAS2R33 TAS2R36 ADGRE3 TREM2 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 ADGRF1 IL2RA IL3RA EPHA8	6.27e-07	1353	123	25	GO:0004888
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH3 DYNLT5 DNAH8 DYNC1H1	3.04e-06	37	123	5	GO:0045505
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH3 DNAH8 DYNC1H1	3.92e-06	18	123	4	GO:0008569
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH3 KIF1A KIF1B DNAH8 DYNC1H1	4.59e-06	70	123	6	GO:0003777
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH3 DNAH8 DYNC1H1	2.50e-05	28	123	4	GO:0051959
GeneOntologyMolecularFunction	G protein-coupled receptor activity	LPAR3 HCAR2 HTR5A LPAR1 CCKBR TAS2R33 TAS2R36 ADGRE3 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 ADGRF1	2.99e-05	884	123	17	GO:0004930
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 DNAH3 KIF1A KIF1B DNAH8 DYNC1H1	9.07e-05	118	123	6	GO:0003774
GeneOntologyMolecularFunction	lipid transporter activity	SLC27A6 ATP8B1 STAR GRAMD1B ABCB11 ATG9A SLC51A	2.15e-04	196	123	7	GO:0005319
GeneOntologyMolecularFunction	RNA polymerase I core binding	RRN3P2 RRN3	2.24e-04	4	123	2	GO:0001042
GeneOntologyMolecularFunction	lysophosphatidic acid receptor activity	LPAR3 LPAR1	3.72e-04	5	123	2	GO:0070915
GeneOntologyMolecularFunction	lipoteichoic acid binding	CD14 TREM2	7.75e-04	7	123	2	GO:0070891
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	RRN3P2 RRN3	1.32e-03	9	123	2	GO:0001181
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 DNAH3 KIF1A SLC27A6 KIF1B ATP8B1 MDN1 ABCB11 ABCC2 DNAH8 DYNC1H1	1.46e-03	614	123	11	GO:0140657
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of bitter taste	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	7.54e-14	44	122	10	GO:0001580
GeneOntologyBiologicalProcess	sensory perception of bitter taste	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.95e-13	48	122	10	GO:0050913
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of taste	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	3.03e-13	50	122	10	GO:0050912
GeneOntologyBiologicalProcess	sensory perception of taste	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.06e-11	70	122	10	GO:0050909
GeneOntologyBiologicalProcess	nucleus localization	KIF1A SYNE1 MTOR SLIT1 DYNC1H1	6.02e-06	44	122	5	GO:0051647
GeneOntologyBiologicalProcess	nuclear migration	KIF1A SYNE1 SLIT1 DYNC1H1	4.71e-05	34	122	4	GO:0007097
GeneOntologyCellularComponent	motile cilium	DNHD1 DNAH3 CATSPER2 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 DNAH8	1.79e-06	355	127	12	GO:0031514
GeneOntologyCellularComponent	microtubule associated complex	DNHD1 DNAH3 KIF1A FNTB KIF1B DYNLT5 DNAH8 DYNC1H1	6.42e-06	161	127	8	GO:0005875
GeneOntologyCellularComponent	dynein complex	DNHD1 DNAH3 DYNLT5 DNAH8 DYNC1H1	1.91e-05	54	127	5	GO:0030286
GeneOntologyCellularComponent	ATR-ATRIP complex	ATR ATRIP	3.66e-05	2	127	2	GO:0070310
GeneOntologyCellularComponent	intracellular canaliculus	ABCB11 ABCC2	3.62e-04	5	127	2	GO:0046691
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAH3 DNAH8	4.57e-04	25	127	3	GO:0005858
HumanPheno	Conjugated hyperbilirubinemia	UBR1 ATP8B1 ABCB11 ABCC2 SLC51A	4.85e-06	38	35	5	HP:0002908
HumanPheno	Intrahepatic cholestasis	UBR1 ATP8B1 ABCB11 SLC51A	2.13e-05	25	35	4	HP:0001406
HumanPheno	Abnormal liver physiology	UBR1 ATP8B1 ABCB11 SLC51A	2.51e-05	26	35	4	HP:0031865
Domain	TAS2R	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	3.72e-12	26	122	8	PF05296
Domain	T2R	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	3.72e-12	26	122	8	IPR007960
Domain	Dynein_HC_stalk	DNHD1 DNAH3 DNAH8 DYNC1H1	1.65e-06	14	122	4	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH3 DNAH8 DYNC1H1	1.65e-06	14	122	4	IPR013602
Domain	DHC_N2	DNHD1 DNAH3 DNAH8 DYNC1H1	1.65e-06	14	122	4	PF08393
Domain	MT	DNHD1 DNAH3 DNAH8 DYNC1H1	1.65e-06	14	122	4	PF12777
Domain	ATPase_dyneun-rel_AAA	DNAH3 MDN1 DNAH8 DYNC1H1	1.65e-06	14	122	4	IPR011704
Domain	AAA_5	DNAH3 MDN1 DNAH8 DYNC1H1	1.65e-06	14	122	4	PF07728
Domain	DHC_fam	DNHD1 DNAH3 DNAH8 DYNC1H1	2.24e-06	15	122	4	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH3 DNAH8 DYNC1H1	2.24e-06	15	122	4	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH3 DNAH8 DYNC1H1	2.24e-06	15	122	4	PF03028
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH8 DYNC1H1	9.39e-05	14	122	3	IPR024317
Domain	AAA_8	DNAH3 DNAH8 DYNC1H1	9.39e-05	14	122	3	PF12780
Domain	Hist_deacetylase_Gln_rich_N	HDAC9 HDAC5	1.26e-04	3	122	2	IPR024643
Domain	HDAC4_Gln	HDAC9 HDAC5	1.26e-04	3	122	2	PF12203
Domain	LPA_rcpt	LPAR3 LPAR1	1.26e-04	3	122	2	IPR004065
Domain	Kinesin-like_KIF1-typ	KIF1A KIF1B	2.52e-04	4	122	2	IPR022140
Domain	LRRC37AB_C	LRRC37A2 LRRC37A	2.52e-04	4	122	2	PF14914
Domain	KIF1B	KIF1A KIF1B	2.52e-04	4	122	2	PF12423
Domain	LRRC37_N	LRRC37A2 LRRC37A	2.52e-04	4	122	2	IPR032754
Domain	LRRC37AB_C	LRRC37A2 LRRC37A	2.52e-04	4	122	2	IPR029423
Domain	LRRC37	LRRC37A2 LRRC37A	2.52e-04	4	122	2	PF15779
Domain	Histone_deAcase_II_euk	HDAC9 HDAC5	2.52e-04	4	122	2	IPR017320
Domain	LRRC37A/B-like	LRRC37A2 LRRC37A	2.52e-04	4	122	2	IPR015753
Domain	-	FBXL14 LRRC37A2 LRRC10 NOD1 LRRC37A CD14 SLIT1 KDM2B GP5	2.61e-04	321	122	9	3.80.10.10
Domain	L_dom-like	FBXL14 LRRC37A2 LRRC10 NOD1 LRRC37A CD14 SLIT1 KDM2B GP5	3.05e-04	328	122	9	IPR032675
Domain	AAA+_ATPase	DNAH3 MDN1 ABCB11 ABCC2 DNAH8 DYNC1H1	3.67e-04	144	122	6	IPR003593
Domain	AAA	DNAH3 MDN1 ABCB11 ABCC2 DNAH8 DYNC1H1	3.67e-04	144	122	6	SM00382
Domain	Leu-rich_rpt	FBXL14 LRRC37A2 LRRC10 NOD1 LRRC37A CD14 SLIT1 GP5	4.10e-04	271	122	8	IPR001611
Domain	FATC	ATR MTOR	4.18e-04	5	122	2	PF02260
Domain	FN3_dom	BOC DSCAM AXL COL14A1 IGSF9B IL3RA EPHA8	4.49e-04	209	122	7	IPR003961
Domain	LRR_1	FBXL14 LRRC37A2 LRRC10 LRRC37A CD14 SLIT1 GP5	5.93e-04	219	122	7	PF00560
Domain	Kinesin_assoc	KIF1A KIF1B	6.24e-04	6	122	2	PF16183
Domain	FAT	ATR MTOR	6.24e-04	6	122	2	PS51189
Domain	FATC	ATR MTOR	6.24e-04	6	122	2	PS51190
Domain	Kinesin_assoc	KIF1A KIF1B	6.24e-04	6	122	2	IPR032405
Domain	FAT	ATR MTOR	6.24e-04	6	122	2	PF02259
Domain	PIK-rel_kinase_FAT	ATR MTOR	6.24e-04	6	122	2	IPR003151
Domain	FATC_dom	ATR MTOR	6.24e-04	6	122	2	IPR003152
Domain	DUF3694	KIF1A KIF1B	6.24e-04	6	122	2	PF12473
Domain	PIK_FAT	ATR MTOR	6.24e-04	6	122	2	IPR014009
Domain	Kinesin-like	KIF1A KIF1B	6.24e-04	6	122	2	IPR022164
Domain	FATC	ATR MTOR	6.24e-04	6	122	2	SM01343
Domain	fn3	BOC DSCAM AXL COL14A1 IGSF9B EPHA8	6.85e-04	162	122	6	PF00041
Domain	DHC_N1	DNAH8 DYNC1H1	1.15e-03	8	122	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH8 DYNC1H1	1.15e-03	8	122	2	IPR013594
Domain	FN3	BOC DSCAM AXL COL14A1 IGSF9B EPHA8	1.36e-03	185	122	6	SM00060
Domain	FN3	BOC DSCAM AXL COL14A1 IGSF9B EPHA8	1.97e-03	199	122	6	PS50853
Domain	Ig_V-set	BOC DSCAM AXL SIRPB1 TREM2 IGSF9B	1.97e-03	199	122	6	IPR013106
Domain	LRR	LRRC37A2 LRRC10 LRRC37A CD14 SLIT1 GP5	2.07e-03	201	122	6	PS51450
Domain	Hist_deacetyl	HDAC9 HDAC5	2.24e-03	11	122	2	PF00850
Domain	His_deacetylse_dom	HDAC9 HDAC5	2.24e-03	11	122	2	IPR023801
Domain	-	HDAC9 HDAC5	2.24e-03	11	122	2	3.40.800.20
Domain	His_deacetylse	HDAC9 HDAC5	2.24e-03	11	122	2	IPR000286
Domain	-	BOC DSCAM AXL SIRPB1 NTM VSIG10L TREM2 COL14A1 IGSF9B IL3RA EPHA8	4.13e-03	663	122	11	2.60.40.10
Domain	PI3/4_kinase_CS	ATR MTOR	4.20e-03	15	122	2	IPR018936
Domain	WD40_repeat_CS	GNB1L CORO2B LLGL2 WDR97 WDR90	4.46e-03	164	122	5	IPR019775
Domain	FBOX	FBXL14 KDM2B FBXO15	4.76e-03	52	122	3	SM00256
Domain	-	ATR MTOR	4.78e-03	16	122	2	1.10.1070.11
Domain	PI3Kc	ATR MTOR	4.78e-03	16	122	2	SM00146
Domain	LRR_8	LRRC37A2 LRRC10 LRRC37A SLIT1 GP5	5.32e-03	171	122	5	PF13855
Domain	PI3/4_kinase_cat_dom	ATR MTOR	6.05e-03	18	122	2	IPR000403
Domain	PI3_PI4_kinase	ATR MTOR	6.05e-03	18	122	2	PF00454
Domain	PI3_4_KINASE_3	ATR MTOR	6.05e-03	18	122	2	PS50290
Domain	PI3_4_KINASE_1	ATR MTOR	6.05e-03	18	122	2	PS00915
Domain	PI3_4_KINASE_2	ATR MTOR	6.05e-03	18	122	2	PS00916
Domain	Leu-rich_rpt_typical-subtyp	LRRC37A2 LRRC10 LRRC37A SLIT1 GP5	6.14e-03	177	122	5	IPR003591
Domain	LRR_TYP	LRRC37A2 LRRC10 LRRC37A SLIT1 GP5	6.14e-03	177	122	5	SM00369
Domain	IG	BOC DSCAM AXL SIRPB1 NTM VSIG10L TREM2 IGSF9B	6.44e-03	421	122	8	SM00409
Domain	Ig_sub	BOC DSCAM AXL SIRPB1 NTM VSIG10L TREM2 IGSF9B	6.44e-03	421	122	8	IPR003599
Domain	Laminin_G	LAMA3 SLIT1 COL14A1	6.46e-03	58	122	3	IPR001791
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	3.91e-11	31	102	8	MM15691
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.85e-10	37	102	8	MM15067
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.07e-08	39	102	7	M793
Pathway	KEGG_TASTE_TRANSDUCTION	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R46 TAS2R50	8.64e-08	52	102	7	M5785
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R31 TAS2R43 TAS2R20 TAS2R30 TAS2R46 TAS2R50	1.04e-06	47	102	6	M42524
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	LPAR3 HCAR2 HTR5A LPAR1 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.15e-06	289	102	12	MM15057
Pathway	WP_GPCRS_ODORANT	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50 ADGRF1	1.98e-06	157	102	9	MM15872
Pathway	REACTOME_GPCR_LIGAND_BINDING	QRFP LPAR3 HCAR2 HTR5A LPAR1 CCKBR TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	2.51e-06	430	102	14	MM15160
Pathway	REACTOME_GPCR_LIGAND_BINDING	QRFP LPAR3 HCAR2 HTR5A LPAR1 CCKBR ADGRE3 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	5.90e-06	463	102	14	M507
Pathway	REACTOME_SENSORY_PERCEPTION	FNTB TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	9.46e-06	190	102	9	MM15687
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	LPAR3 HCAR2 HTR5A LPAR1 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.65e-05	314	102	11	M600
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	ATP8B1 ABCB11 ABCC2 SLC51A	5.34e-05	29	102	4	M45551
Pathway	WP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS	ABCB11 ABCC2 SLC51A	7.72e-05	12	102	3	M48096
Pathway	REACTOME_SIGNALING_BY_GPCR	QRFP LPAR3 HCAR2 HTR5A LPAR1 CCKBR TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	2.23e-04	646	102	14	MM14962
Pathway	WP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY	ABCB11 ABCC2 SLC51A	2.32e-04	17	102	3	M39666
Pathway	WP_CHOLESTASIS	ATP8B1 ABCB11 ABCC2	3.28e-04	19	102	3	M45520
Pathway	REACTOME_SIGNALING_BY_GPCR	QRFP LPAR3 HCAR2 HTR5A LPAR1 CCKBR ADGRE3 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	5.16e-04	702	102	14	M746
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.50e-17	12	130	8	12379855
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	3.88e-17	13	130	8	15938754
Pubmed	A novel family of mammalian taste receptors.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	5.98e-15	21	130	8	10761934
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	9.37e-15	22	130	8	12734386
Pubmed	Receptors for bitter and sweet taste.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	3.14e-14	25	130	8	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	4.52e-14	26	130	8	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	6.41e-14	27	130	8	12581520
Pubmed	Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.67e-13	30	130	8	17273929
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.67e-13	30	130	8	12679530
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R45 TAS2R31 TAS2R43 TAS2R19 TAS2R30 TAS2R46 TAS2R50	2.02e-12	23	130	7	20022913
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R45 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	9.60e-12	28	130	7	15744053
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	4.28e-11	34	130	7	15496549
Pubmed	Identification and characterization of human taste receptor genes belonging to the TAS2R family.	TAS2R31 TAS2R43 TAS2R20 TAS2R46 TAS2R50	8.48e-10	13	130	5	12584440
Pubmed	Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content.	ATP8B1 ABCB11 ABCC2	5.10e-08	3	130	3	19228692
Pubmed	Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.	RRN3P2 MTOR RRN3	5.08e-07	5	130	3	21228155
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GALNT1 ATR AXL COQ6 ATP8B1 HUWE1 CCDC115 LPAR1 NDUFS2 CS MDN1 UGGT2 ATG9A RAB32 ALG6 ABHD16A	2.36e-06	1061	130	16	33845483
Pubmed	HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.	KIF1A KIF1B DYNC1H1	2.82e-06	8	130	3	25818806
Pubmed	Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.	RRN3P2 RRN3	1.39e-05	2	130	2	12015311
Pubmed	Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.	TAS2R43 TAS2R50	1.39e-05	2	130	2	33461297
Pubmed	Quantitative trait loci mapping for cholesterol gallstones in AKR/J and C57L/J strains of mice.	ABCB11 ABCC2	1.39e-05	2	130	2	11074014
Pubmed	A neuroprotective phase precedes striatal degeneration upon nucleolar stress.	RRN3P2 RRN3	1.39e-05	2	130	2	23764776
Pubmed	Clinical value of CD25/CD123 co-expression in acute myeloid leukemia patients.	IL2RA IL3RA	1.39e-05	2	130	2	32417762
Pubmed	The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors.	KIF1A KIF1B	1.39e-05	2	130	2	7539720
Pubmed	Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?	LPAR3 LPAR1	1.39e-05	2	130	2	18006645
Pubmed	Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3.	LPAR3 LPAR1	1.39e-05	2	130	2	17923111
Pubmed	Differential effects of membrane cholesterol content on the transport activity of multidrug resistance-associated protein 2 (ABCC2) and of the bile salt export pump (ABCB11).	ABCB11 ABCC2	1.39e-05	2	130	2	24711118
Pubmed	Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump.	ABCB11 ABCC2	1.39e-05	2	130	2	18176959
Pubmed	Non-motor symptoms associated with progressive loss of dopaminergic neurons in a mouse model of Parkinson's disease.	RRN3P2 RRN3	1.39e-05	2	130	2	38745938
Pubmed	Bitter taste receptors for saccharin and acesulfame K.	TAS2R31 TAS2R43	1.39e-05	2	130	2	15537898
Pubmed	Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.	RRN3P2 RRN3	1.39e-05	2	130	2	8413268
Pubmed	LPAR1 and aberrantly expressed LPAR3 differentially promote the migration and proliferation of malignant peripheral nerve sheath tumor cells.	LPAR3 LPAR1	1.39e-05	2	130	2	36416236
Pubmed	Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities.	ATR ATRIP	1.39e-05	2	130	2	14729973
Pubmed	Upregulation of HO-1 is accompanied by activation of p38MAPK and mTOR in human oesophageal squamous carcinoma cells.	HMOX1 MTOR	1.39e-05	2	130	2	23412940
Pubmed	Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.	RRN3P2 RRN3	1.39e-05	2	130	2	30918302
Pubmed	Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation.	LPAR3 LPAR1	1.39e-05	2	130	2	20360252
Pubmed	Chronic immune activation in common variable immunodeficiency (CVID) is associated with elevated serum levels of soluble CD14 and CD25 but not endotoxaemia.	CD14 IL2RA	1.39e-05	2	130	2	23121673
Pubmed	Lysophosphatidic acid enhanced the osteogenic and angiogenic capability of osteoblasts via LPA1/3 receptor.	LPAR3 LPAR1	1.39e-05	2	130	2	29447019
Pubmed	Mutations of lysophosphatidic acid receptor genes in human osteosarcoma cells.	LPAR3 LPAR1	1.39e-05	2	130	2	21116120
Pubmed	Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning.	RRN3P2 RRN3	1.39e-05	2	130	2	27257073
Pubmed	ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.	RRN3P2 RRN3	1.39e-05	2	130	2	12620228
Pubmed	Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage.	ATR ATRIP	1.39e-05	2	130	2	15527801
Pubmed	Hepatotoxicity from anabolic androgenic steroids marketed as dietary supplements: contribution from ATP8B1/ABCB11 mutations?	ATP8B1 ABCB11	1.39e-05	2	130	2	23750872
Pubmed	Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice.	LPAR3 LPAR1	1.39e-05	2	130	2	25411045
Pubmed	Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.	TAS2R31 TAS2R43	1.39e-05	2	130	2	17702579
Pubmed	Differences in presentation and progression between severe FIC1 and BSEP deficiencies.	ATP8B1 ABCB11	1.39e-05	2	130	2	20447715
Pubmed	Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome.	ATR ATRIP	1.39e-05	2	130	2	23144622
Pubmed	The Features of GGT in Patients with ATP8B1 or ABCB11 Deficiency Improve the Diagnostic Efficiency.	ATP8B1 ABCB11	1.39e-05	2	130	2	27050426
Pubmed	Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice.	LPAR3 LPAR1	1.39e-05	2	130	2	27883026
Pubmed	Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.	ABCB11 ABCC2	1.39e-05	2	130	2	22673116
Pubmed	Mec1/ATR, the Program Manager of Nucleic Acids Inc.	ATR ATRIP	1.39e-05	2	130	2	28036033
Pubmed	An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.	LPAR3 LPAR1	1.39e-05	2	130	2	27641212
Pubmed	ATR-dependent phosphorylation of ATRIP in response to genotoxic stress.	ATR ATRIP	1.39e-05	2	130	2	15451423
Pubmed	Cell density-dependent expression of EDG family receptors and mesangial cell proliferation: role in lysophosphatidic acid-mediated cell growth.	LPAR3 LPAR1	1.39e-05	2	130	2	15292052
Pubmed	ATR and ATRIP: partners in checkpoint signaling.	ATR ATRIP	1.39e-05	2	130	2	11721054
Pubmed	RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids.	RANBP17 SPEM1	1.39e-05	2	130	2	21184802
Pubmed	Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases.	RRN3P2 RRN3	1.39e-05	2	130	2	31110473
Pubmed	ATP8B1 Deficiency	ATP8B1 ABCB11	1.39e-05	2	130	2	20301474
Pubmed	DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.	RRN3P2 RRN3	1.39e-05	2	130	2	23393135
Pubmed	Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons.	RRN3P2 RRN3	1.39e-05	2	130	2	24273493
Pubmed	Mesenchymal stromal cells inhibit CD25 expression via the mTOR pathway to potentiate T-cell suppression.	MTOR IL2RA	1.39e-05	2	130	2	28230853
Pubmed	ATRIP oligomerization is required for ATR-dependent checkpoint signaling.	ATR ATRIP	1.39e-05	2	130	2	16027118
Pubmed	ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.	ATR ATRIP	1.39e-05	2	130	2	20861269
Pubmed	ATP8B1 and ABCB11 analysis in 62 children with normal gamma-glutamyl transferase progressive familial intrahepatic cholestasis (PFIC): phenotypic differences between PFIC1 and PFIC2 and natural history.	ATP8B1 ABCB11	1.39e-05	2	130	2	20232290
Pubmed	Proliferation of mouse endometrial stromal cells in culture is highly sensitive to lysophosphatidic acid signaling.	LPAR3 LPAR1	1.39e-05	2	130	2	28073697
Pubmed	Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.	HDAC9 HDAC5	1.39e-05	2	130	2	17988634
Pubmed	Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age.	SLC2A14 STAR MTOR SLIT1	1.53e-05	40	130	4	36843585
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH8 DYNC1H1	1.80e-05	14	130	3	9373155
Pubmed	Defining the membrane proteome of NK cells.	ACAP1 GALNT1 HUWE1 CCDC115 GRAMD1B LMF2 MDN1 MTOR ALDH16A1 TUBGCP3 ATG9A HEATR5B AKAP1 ALG6 DYNC1H1	3.27e-05	1168	130	15	19946888
Pubmed	hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis.	ATR ATRIP	4.15e-05	3	130	2	21285353
Pubmed	NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.	SLC2A14 MTOR	4.15e-05	3	130	2	25578782
Pubmed	Heterozygous mutations of ATP8B1, ABCB11 and ABCB4 cause mild forms of Progressive Familial Intrahepatic Cholestasis in a pediatric cohort.	ATP8B1 ABCB11	4.15e-05	3	130	2	34942279
Pubmed	Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.	ATR ATRIP	4.15e-05	3	130	2	18344416
Pubmed	A novel protein activity mediates DNA binding of an ATR-ATRIP complex.	ATR ATRIP	4.15e-05	3	130	2	14724280
Pubmed	Activation of nucleotide oligomerization domain containing protein 1 induces lipolysis through NF-κB and the lipolytic PKA activation in 3T3-L1 adipocytes.	NOD1 AKAP1	4.15e-05	3	130	2	24219284
Pubmed	Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.	ATR ATRIP	4.15e-05	3	130	2	18283122
Pubmed	Enhancement of invasion of hepatocellular carcinoma cells through lysophosphatidic acid receptor.	LPAR3 LPAR1	4.15e-05	3	130	2	23569130
Pubmed	Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors.	LPAR3 LPAR1	4.15e-05	3	130	2	12123830
Pubmed	Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.	ABCB11 ABCC2	4.15e-05	3	130	2	18245269
Pubmed	Clinical phenotype of adult-onset liver disease in patients with variants in ABCB4, ABCB11, and ATP8B1.	ATP8B1 ABCB11	4.15e-05	3	130	2	35894240
Pubmed	Lysophosphatidic acid stimulates cell growth by different mechanisms in SKOV-3 and Caov-3 ovarian cancer cells: distinct roles for Gi- and Rho-dependent pathways.	LPAR3 LPAR1	4.15e-05	3	130	2	19420982
Pubmed	The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.	LPAR3 LPAR1	4.15e-05	3	130	2	32296017
Pubmed	HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.	ATR ATRIP	4.15e-05	3	130	2	17384638
Pubmed	Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.	LPAR3 LPAR1	4.15e-05	3	130	2	19899077
Pubmed	Lysophosphatidic acid receptors.	LPAR3 LPAR1	4.15e-05	3	130	2	11093753
Pubmed	CD14 is a key mediator of both lysophosphatidic acid and lipopolysaccharide induction of foam cell formation.	LPAR1 CD14	4.15e-05	3	130	2	28705936
Pubmed	LPA receptor expression in the central nervous system in health and following injury.	LPAR3 LPAR1	4.15e-05	3	130	2	20495828
Pubmed	Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis.	LPAR3 LPAR1	4.15e-05	3	130	2	24829209
Pubmed	Functional genomic screens identify CINP as a genome maintenance protein.	ATR ATRIP	4.15e-05	3	130	2	19889979
Pubmed	Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia.	LPAR3 LPAR1	4.15e-05	3	130	2	19025891
Pubmed	BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.	KIF1A KIF1B	4.15e-05	3	130	2	27851960
Pubmed	Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions.	ADGRF1 IL2RA	4.15e-05	3	130	2	28866095
Pubmed	The Src family kinase Fyn mediates hyperosmolarity-induced Mrp2 and Bsep retrieval from canalicular membrane.	ABCB11 ABCC2	4.15e-05	3	130	2	22057277
Pubmed	miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity.	ATP8B1 ABCB11	4.15e-05	3	130	2	22767443
Pubmed	TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation.	RRN3P2 RRN3	4.15e-05	3	130	2	19217408
Pubmed	Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage.	ATR ATRIP	4.15e-05	3	130	2	17638878
Pubmed	Mitochondrial AKAP1 supports mTOR pathway and tumor growth.	MTOR AKAP1	4.15e-05	3	130	2	28569781
Pubmed	HIF1-regulated ATRIP expression is required for hypoxia induced ATR activation.	ATR ATRIP	4.15e-05	3	130	2	23454212
Pubmed	Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling.	LPAR3 LPAR1	4.15e-05	3	130	2	18448840
Pubmed	TopBP1 activates ATR through ATRIP and a PIKK regulatory domain.	ATR ATRIP	4.15e-05	3	130	2	18519640
Pubmed	mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms.	HDAC9 MTOR	4.15e-05	3	130	2	24562770
Cytoband	12p13.2	TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	4.36e-11	45	127	7	12p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	LINC01559 FBXL14 SLC2A14 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	6.00e-08	353	127	10	chr12p13
Cytoband	1p36.2	KIF1B MTOR	5.81e-04	13	127	2	1p36.2
GeneFamily	Taste 2 receptors	TAS2R33 TAS2R36 TAS2R45 TAS2R31 TAS2R43 TAS2R20 TAS2R19 TAS2R30 TAS2R46 TAS2R50	1.96e-15	39	86	10	1162
GeneFamily	Fibronectin type III domain containing	BOC DSCAM AXL COL14A1 IGSF9B EPHA8	1.15e-04	160	86	6	555
GeneFamily	Histone deacetylases, class IIA	HDAC9 HDAC5	1.33e-04	4	86	2	992
GeneFamily	Lysophosphatidic acid receptors	LPAR3 LPAR1	3.31e-04	6	86	2	205
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL17RE IL2RA IL3RA	1.04e-03	42	86	3	602
GeneFamily	Immunoglobulin like domain containing	BOC DSCAM AXL VSIG10L IGSF9B	2.28e-03	193	86	5	594
GeneFamily	Dyneins, axonemal	DNAH3 DNAH8	2.90e-03	17	86	2	536
GeneFamily	F-box and leucine rich repeat proteins	FBXL14 KDM2B	4.43e-03	21	86	2	558
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	BOC DSCAM NTM IGSF9B	7.31e-03	161	86	4	593
GeneFamily	Adenosine receptors\|V-set domain containing	AXL SIRPB1 TREM2 IGSF9B	7.63e-03	163	86	4	590
GeneFamily	WD repeat domain containing	GNB1L CORO2B LLGL2 WDR97 WDR90	8.26e-03	262	86	5	362
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP1 RAB32	8.35e-03	29	86	2	396
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	AXL LAD1 ACTN2 HMOX1 LYVE1 CD14 TREM2	1.54e-06	196	127	7	e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	AXL LAD1 ACTN2 HMOX1 LYVE1 CD14 TREM2	1.54e-06	196	127	7	3bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCell	background-Kupffer_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HDAC9 DSCAM SLC27A6 AXL HMOX1 LYVE1 CD14	1.70e-06	199	127	7	91d229f3515d49639bcb5505e6aec4a9abade81c
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 ACTN2 IL17RE DYNLT5 IL2RA	7.69e-06	164	127	6	467ad12884b70d243988174ae960ee2b7b6cfb0c
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 ACTN2 IL17RE DYNLT5 IL2RA	7.69e-06	164	127	6	4e1861382c9e93856da19303474c8975c19706d2
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 SLC27A6 ACTN2 STAR IL17RE IL2RA	1.08e-05	174	127	6	aae7ab9df5a78716034ddfd5bd47adc69912d624
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LRRC37A2 URB1 NOD1 LRRC37A ALG6 ABHD16A	1.08e-05	174	127	6	a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 SLC27A6 ACTN2 STAR IL17RE IL2RA	1.08e-05	174	127	6	d9489c4196d103ead8cb6279492bbe563a222e45
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	HCAR2 DSCAM AXL HMOX1 LYVE1 CD14	1.31e-05	180	127	6	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	MS-mono2-\|MS / Condition, Cell_class and T cell subcluster	AXL HMOX1 LYVE1 CD14 TREM2 RAB32	1.39e-05	182	127	6	b5a31df2d26956e83a3afebbdaef953c7bc0d4a0
ToppCell	MS-mono2\|MS / Condition, Cell_class and T cell subcluster	AXL HMOX1 LYVE1 CD14 TREM2 RAB32	1.39e-05	182	127	6	44deaa67b82312139eb83ab93ec41521105b116b
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	AXL LYVE1 CD14 ASB9 TREM2 IL3RA	1.67e-05	188	127	6	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	AXL LYVE1 CD14 ASB9 TREM2 IL3RA	1.67e-05	188	127	6	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE SLC27A6 SYNE1 LPAR1 NTM COL14A1	1.99e-05	194	127	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	distal-Hematologic-Basophil/Mast_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTM DYNLT5 TAS2R43 TAS2R46 IL2RA EPHA8	2.05e-05	195	127	6	a2623f4247c356cf92a0b6f9e454d67edde536ae
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	AXL HMOX1 TFR2 CD14 TAS2R30 DNAH8	2.30e-05	199	127	6	a1ff1063741f6e5569feb44245785c9f472799b2
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE SYNE1 ACTN2 LPAR1 NTM COL14A1	2.37e-05	200	127	6	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	COVID-mono1\|COVID / Condition, Cell_class and T cell subcluster	AXL HMOX1 LYVE1 CD14 TREM2 RAB32	2.37e-05	200	127	6	bd002c54305c746c07b7418a2084195e9c852ec5
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CCL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HMOX1 CD14 ASB9 MRPS15 DSEL NAGPA	2.37e-05	200	127	6	07f2f01c95f2da011cf0f266dc1175082c93136e
ToppCell	COVID-mono1-\|COVID / Condition, Cell_class and T cell subcluster	AXL HMOX1 LYVE1 CD14 TREM2 RAB32	2.37e-05	200	127	6	445a1aab962673dcc926c33ce9bed5ede9c41c57
ToppCell	Caecum-Macrophage-Macrophage\|Caecum / Region, Cell class and subclass	HCAR2 AXL SIRPB1 HMOX1 LYVE1 CD14	2.37e-05	200	127	6	99dcf07b17ecf90d596f3b8a12d5b7aae2a351d5
ToppCell	Caecum-(6)_Macrophage-(60)_Macrophage\|Caecum / shred on region, Cell_type, and subtype	HCAR2 AXL SIRPB1 HMOX1 LYVE1 CD14	2.37e-05	200	127	6	67b6cdeb07ffc5c9af7a3e738dd31256cf391e98
ToppCell	Caecum-(6)_Macrophage\|Caecum / shred on region, Cell_type, and subtype	HCAR2 AXL SIRPB1 HMOX1 LYVE1 CD14	2.37e-05	200	127	6	2ce3930645c3daf6be578f7881e57a58df61e75c
ToppCell	Caecum-Macrophage\|Caecum / Region, Cell class and subclass	HCAR2 AXL SIRPB1 HMOX1 LYVE1 CD14	2.37e-05	200	127	6	d83209559187a4419df2508ecc5eb9f7d72fced3
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE SYNE1 ACTN2 LPAR1 NTM COL14A1	2.37e-05	200	127	6	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TRHDE SYNE1 ACTN2 LPAR1 NTM COL14A1	2.37e-05	200	127	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 SLC27A6 FNTB DPP8 SLIT1	3.20e-05	127	127	5	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocye.Tnr.Cspg5_(Cspg5)\|Striatum / BrainAtlas - Mouse McCarroll V32	ZAN SLC27A6 LAD1 SPATA4	4.81e-05	70	127	4	c6d3f8cd3f79e2beb826b07a6b9f3ab35d4f23ea
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocye.Tnr.Cspg5_(Cspg5)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ZAN SLC27A6 LAD1 SPATA4	4.81e-05	70	127	4	823921f8bf585d45f24f627b2b77b228898eb85a
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P3-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	ZAN SLC27A6 LAD1 SPATA4	4.81e-05	70	127	4	d2be16550c572ba77261c978648e61dba3eab6bd
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P3\|Striatum / BrainAtlas - Mouse McCarroll V32	ZAN SLC27A6 LAD1 SPATA4	4.81e-05	70	127	4	52bde49a05f2387fe3e4357422e155bee2e86ae6
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6\|Thalamus / BrainAtlas - Mouse McCarroll V32	QRFP ZAN ACTN2 LRRC37A	5.08e-05	71	127	4	7623b110bc3db0f5b99803c8fbb881ae8846b817
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 LAMA3 NTM IGSF9B MARCHF11	6.42e-05	147	127	5	989a48bda98fbff398985397a6b1189a4cbc80e7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 LAMA3 NTM IGSF9B MARCHF11	6.42e-05	147	127	5	f6681c849c4c06154548bd29a094f202d1c946c2
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FBXL14 RANBP17 LYVE1 NTM ABCC2	6.84e-05	149	127	5	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FBXL14 RANBP17 LYVE1 NTM ABCC2	6.84e-05	149	127	5	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_4\|367C / Donor, Lineage, Cell class and subclass (all cells)	QRFP HMOX1 CD14 TREM2 TAS2R19	7.75e-05	153	127	5	3570dd844d6479425bf6f62129f88efa45553775
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SNAP47 NOD1 MDN1 TAS2R30 IL2RA	8.00e-05	154	127	5	ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell	Dendritic_Cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	HDAC9 LYVE1 LRRC37A CD14 ABHD16A	8.00e-05	154	127	5	65013f696da623d37f1e3447a294dfb3c31ae93b
ToppCell	droplet-Kidney-nan-18m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL CD14 TREM2 IL2RA IL3RA	8.76e-05	157	127	5	eb64a4e89843895d16015c7d51805f164ed7ea5b
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nfib_(Amygdala)\|Striatum / BrainAtlas - Mouse McCarroll V32	STAR CCKBR VSIG10L FBXO15	8.93e-05	82	127	4	ab081620b6113f843fede23da0a18720111ffc7c
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nfib_(Amygdala)-\|Striatum / BrainAtlas - Mouse McCarroll V32	STAR CCKBR VSIG10L FBXO15	8.93e-05	82	127	4	1ca848a18463b1344e23e3ad1b5d01ae27c00586
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTN2 DYNLT5 SLC51A DNAH8 GP5	9.30e-05	159	127	5	e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTN2 DYNLT5 SLC51A DNAH8 GP5	9.30e-05	159	127	5	9db971130509c62d439e0cab16588a4d994d7aa0
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 ACTN2 ASB9 SLC51A	9.58e-05	160	127	5	1cb6f42b68c9e41e8edae0de8f0d8371c4620b04
ToppCell	facs-Liver-Liver_non-hepato/SCs\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 ACTN2 ASB9 SLC51A	9.58e-05	160	127	5	ebefde92db400cbe68d9ce31545a0308e0afbde1
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_4\|343B / Donor, Lineage, Cell class and subclass (all cells)	HMOX1 CD14 TREM2 TAS2R43 IL3RA	9.86e-05	161	127	5	5cd483b73bcb3615ea56eb81c1c293e61b84b66d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 ACAP1 DSCAM SLC22A15 GP5	1.02e-04	162	127	5	dddf7a3901ae59e3494d8a6740db0fa15cc96d47
ToppCell	droplet-Lung-LUNG-30m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 ACAP1 DSCAM SLC22A15 GP5	1.02e-04	162	127	5	2a4e09545e9874519f0f56e81065104987d81cd6
ToppCell	facs-MAT-Fat-3m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 HMOX1 LYVE1 CD14 TREM2	1.04e-04	163	127	5	5fc836444bc156c8248abee001b0ecbe43f980c9
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_E\|356C / Donor, Lineage, Cell class and subclass (all cells)	LRRC37A2 NOD1 LRRC37A ALG6 ABHD16A	1.08e-04	164	127	5	d5bb57c321f2973836efc8990449494cc1fb87c7
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 AXL HMOX1 CD14 TREM2	1.08e-04	164	127	5	939d4e3911fce185b986639c815de0a0389f6cfd
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 AXL HMOX1 CD14 TREM2	1.08e-04	164	127	5	3281f2452cc6b11f3e030a3942002b9457dde6fe
ToppCell	E15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HMOX1 LYVE1 CD14 TREM2 RAB32	1.11e-04	165	127	5	8d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCell	E15.5-Endothelial-lymphatic_endothelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HMOX1 LYVE1 CD14 TREM2 RAB32	1.11e-04	165	127	5	17ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCell	droplet-Liver-LIVER-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 AXL HMOX1 CD14 TREM2	1.17e-04	167	127	5	a038c522e4783cb62802f613d00bd5f3e3797199
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 HCAR2 AXL CD14 TREM2	1.20e-04	168	127	5	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	mild_COVID-19-HSPC\|mild_COVID-19 / disease group, cell group and cell class (v2)	LAMA3 PGAP4 TFR2 RANBP17 DYNLT5	1.20e-04	168	127	5	90b33962adb77d8326dee403712118398b4d1315
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 HCAR2 AXL SLIT1 TREM2	1.20e-04	168	127	5	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 SLC27A6 ACTN2 IL2RA DNAH8	1.24e-04	169	127	5	3c4c3279cd72f39b5e7ff77741950ed3873c0317
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 HCAR2 AXL CD14 TREM2	1.24e-04	169	127	5	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 AXL HMOX1 CD14 RAB32	1.24e-04	169	127	5	44d841fd997a6f26104f16cd00223ecce8352f43
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ACAP1 LRRC37A2 LAMA3 CATSPER2 NTM	1.24e-04	169	127	5	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 SLC27A6 ACTN2 IL2RA DNAH8	1.24e-04	169	127	5	d6437afa298c280d202ba686338c6d8a37bd7ab7
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ACAP1 LRRC37A2 LAMA3 CATSPER2 NTM	1.24e-04	169	127	5	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAD1 ATP8B1 LLGL2 TAS2R50 AKAP1	1.31e-04	171	127	5	3ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HDAC9 HMOX1 CD14 TREM2 RAB32	1.31e-04	171	127	5	bf475a69db04d4a886e442704955c6a96ff0de46
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAD1 ATP8B1 LLGL2 TAS2R50 AKAP1	1.31e-04	171	127	5	3a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 ACTN2 IL17RE IL2RA	1.31e-04	171	127	5	246fc7edcefc47437d1df6029f295aca3b34b2b2
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 ACTN2 IL17RE IL2RA	1.31e-04	171	127	5	1fb4e11f92b48dc2d6e553c22e2571bbd8c223c6
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 AXL HMOX1 CD14 RAB32	1.31e-04	171	127	5	35acc5c3e36bc605603c0d45375f2cf3c3e9d4cd
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACAP1 SLC27A6 ACTN2 IL17RE IL2RA	1.38e-04	173	127	5	0a355386210a13927ea29b10b64cb059459952d4
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACAP1 SLC27A6 ACTN2 IL17RE IL2RA	1.38e-04	173	127	5	3678b300cad4effd7f49bfb043305ed512693848
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	SLC2A14 LAMA3 PGAP4 LLGL2 NTM	1.38e-04	173	127	5	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL HMOX1 CD14 TREM2 RAB32	1.42e-04	174	127	5	3533a47885af453d97739e5576e989d93d31be32
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL HMOX1 CD14 TREM2 RAB32	1.42e-04	174	127	5	dc4298c1d9359f7e37454e9451f889017227d5cf
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL HMOX1 CD14 TREM2 RAB32	1.42e-04	174	127	5	b487c5c46f074a69b9526a2c72daf218f66aa44b
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMOX1 LYVE1 CD14 ADGRE3 TREM2	1.46e-04	175	127	5	fe27c3279f660b5be4193005394b77163c599d32
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 STAR CATSPER2 IL2RA	1.50e-04	176	127	5	096cbcefd9dcbaee660568998ba210253b58501e
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	SLC22A15 LYVE1 URB1 VSIG10L NEURL4	1.50e-04	176	127	5	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP ACAP1 STAR CATSPER2 IL2RA	1.50e-04	176	127	5	90198fb79e8b08e9e7df538cbc05ad7141e78517
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	HMOX1 LYVE1 UGGT2 TAS2R46 ALG6	1.54e-04	177	127	5	52c2ba74a8605260a2623e7d151286e504ac4d19
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	AXL HMOX1 LYVE1 CD14 TREM2	1.54e-04	177	127	5	945b2d0723a0a35c767604ae607d2c2d53bf0c82
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 ACTN2 GRAMD1B IL17RE IL2RA	1.54e-04	177	127	5	baf78a8dad55f124f56585f88b10b58c0269680f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	KIF1A SYNE1 TNRC6C MDN1 DYNC1H1	1.54e-04	177	127	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABRA LPAR3 AXL ATP8B1 DYNLT5	1.58e-04	178	127	5	7467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC22A15 CD14 WDR97 ASB9 TREM2	1.58e-04	178	127	5	c90e9048fc786ba8559972ae25c25ecab4bc1b7c
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC22A15 CD14 WDR97 ASB9 TREM2	1.58e-04	178	127	5	9e426ce23a4a33b91d139ad85685cf8483bcd01a
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Macrophage\|bone_marrow / Manually curated celltypes from each tissue	TRHDE AXL HMOX1 LPAR1 TREM2	1.58e-04	178	127	5	11a338032b59b936c5e65517c4160f7dd47a2cda
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SIRPB1 GRAMD1B CD14 ADGRE3 TREM2	1.62e-04	179	127	5	716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DSCAM LAMA3 RANBP17 LLGL2 IL17RE	1.62e-04	179	127	5	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-NK_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 SLC27A6 ACTN2 IL17RE IL2RA	1.62e-04	179	127	5	6f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRHDE FBXL14 CORO2B CD14 ABHD16A	1.62e-04	179	127	5	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LAMA3 PGAP4 LPAR1 RANBP17 NTM	1.62e-04	179	127	5	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE ACTN2 LPAR1 NTM COL14A1	1.66e-04	180	127	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	10x5'-GI_large-bowel-Myeloid_Dendritic\|GI_large-bowel / Manually curated celltypes from each tissue	HCAR2 HMOX1 IL17RE ABCB11 RAB32	1.66e-04	180	127	5	400f48aa2851d89bf3b60d721bc0f635f3ad86eb
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAP1 SLC27A6 ACTN2 IL17RE IL2RA	1.66e-04	180	127	5	5c649e2b3f5a53c0040b69df6e289fb3427ef2db
ToppCell	AT1_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	HDAC9 LAMA3 LLGL2 IL17RE NTM	1.66e-04	180	127	5	2d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell	VE-mono2-\|VE / Condition, Cell_class and T cell subcluster	AXL HMOX1 CD14 TREM2 RAB32	1.66e-04	180	127	5	188e7c65e9a86771f89029b18dfb3216b2c9d7d7
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRHDE ACTN2 LPAR1 NTM COL14A1	1.66e-04	180	127	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
Drug	Harzol	STAR NOD1 CD14 ABCB11 ABCC2 SLC51A	1.34e-06	63	126	6	CID000006744
Drug	coproporphyrin I	BOC COQ6 DPP8 ABCC2	2.58e-06	18	126	4	CID000068271
Drug	NSC119914	BOC SYNE1 TFR2 ABCB11	6.05e-06	22	126	4	CID000274126
Drug	H944	BOC LAD1 NANOS2 MTOR ABCC2 IL2RA	1.23e-05	92	126	6	CID000004271
Drug	fluoromethylene	LPAR3 LPAR1 MTOR	1.36e-05	9	126	3	CID000186213
Disease	Cholestasis of pregnancy	ATP8B1 ABCB11 ABCC2	3.71e-06	8	121	3	C0268318
Disease	Colorectal Carcinoma	BOC DNAH3 ACAP1 HTR5A SYNE1 SLC22A15 LPAR1 CORO2B ABCB11 ABCC2 DSEL DNAH8	3.30e-05	702	121	12	C0009402
Disease	Progressive intrahepatic cholestasis (disorder)	ATP8B1 ABCB11	4.99e-05	3	121	2	C0268312
Disease	Progressive familial intrahepatic cholestasis type 3	ATP8B1 ABCB11	4.99e-05	3	121	2	cv:C1865643
Disease	Cholestasis, benign recurrent intrahepatic 1	ATP8B1 ABCB11	4.99e-05	3	121	2	C4551899
Disease	intrahepatic cholestasis (is_implicated_in)	ATP8B1 ABCB11	9.95e-05	4	121	2	DOID:1852 (is_implicated_in)
Disease	Cholestasis, progressive familial intrahepatic 1	ATP8B1 ABCB11	9.95e-05	4	121	2	C4551898
Disease	pancreatic cancer (implicated_via_orthology)	CCKBR MTOR	9.95e-05	4	121	2	DOID:1793 (implicated_via_orthology)
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A KIF1B	9.95e-05	4	121	2	DOID:0050890 (biomarker_via_orthology)
Disease	limb ischemia (implicated_via_orthology)	HMOX1 CS	1.65e-04	5	121	2	DOID:0050852 (implicated_via_orthology)
Disease	Seckel syndrome (implicated_via_orthology)	ATR ATRIP	3.46e-04	7	121	2	DOID:0050569 (implicated_via_orthology)
Disease	Intrahepatic Cholestasis	ATP8B1 ABCB11	3.46e-04	7	121	2	C0008372
Disease	Malignant neoplasm of breast	KPNA5 BOC ACAP1 SYNE1 GNB1L LRRC37A2 ATP8B1 HMOX1 LPAR1 LMF2 LLGL2 LRRC37A MTOR	4.75e-04	1074	121	13	C0006142
Disease	Gout	CD14 ALDH16A1	5.89e-04	9	121	2	C0018099
Disease	cholestasis (implicated_via_orthology)	ABCB11 ABCC2	5.89e-04	9	121	2	DOID:13580 (implicated_via_orthology)
Disease	middle cerebral artery infarction (biomarker_via_orthology)	HDAC9 HDAC5 HMOX1 MTOR	5.93e-04	93	121	4	DOID:3525 (biomarker_via_orthology)
Disease	3-methylglutarylcarnitine (2) measurement	SUCLG2 GLDC	8.95e-04	11	121	2	EFO_0800074
Disease	Colorectal Neoplasms	BOC SYNE1 SLC22A15 LPAR1 ABCB11 ABCC2	1.01e-03	277	121	6	C0009404
Disease	Schizophrenia	HDAC9 HCAR2 HTR5A GNB1L SIRPB1 HMOX1 LPAR1 MTOR KDM2B IL2RA IL3RA	1.04e-03	883	121	11	C0036341
Disease	urate measurement, bone density	LPAR3 DSCAM SYNE1 GRAMD1B RANBP17 NTM ADGRE3 UGGT2 DNAH8	1.05e-03	619	121	9	EFO_0003923, EFO_0004531
Disease	nervous system disease (implicated_via_orthology)	KIF1A KIF1B	1.07e-03	12	121	2	DOID:863 (implicated_via_orthology)
Disease	cholestasis (biomarker_via_orthology)	CD14 ABCB11 ABCC2	1.08e-03	49	121	3	DOID:13580 (biomarker_via_orthology)
Disease	brain aneurysm	HDAC9 FMO4 DSCAM SLC2A14	1.23e-03	113	121	4	EFO_0003870
Disease	Malformations of Cortical Development	MTOR DYNC1H1	1.47e-03	14	121	2	C1955869
Disease	X-21470 measurement	ABCC2 SLC51A	1.47e-03	14	121	2	EFO_0800817
Disease	Cortical Dysplasia	MTOR DYNC1H1	1.47e-03	14	121	2	C0431380
Disease	Charcot-Marie-Tooth disease type 2	KIF1B DYNC1H1	2.18e-03	17	121	2	cv:C0270914
Disease	myocardial infarction (implicated_via_orthology)	HMOX1 CS MTOR	2.55e-03	66	121	3	DOID:5844 (implicated_via_orthology)
Disease	portal hypertension (implicated_via_orthology)	HMOX1 MTOR	2.72e-03	19	121	2	DOID:10762 (implicated_via_orthology)
Disease	Chronic myeloproliferative disorder	ATR ATRIP	2.72e-03	19	121	2	C1292778
Disease	susceptibility to mononucleosis measurement	HDAC9 MDN1 DNAH8	2.89e-03	69	121	3	EFO_0008403
Disease	end stage renal disease (implicated_via_orthology)	MTOR ABCC2	3.02e-03	20	121	2	DOID:783 (implicated_via_orthology)
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	HMOX1 STAR MTOR ABCC2	3.20e-03	147	121	4	DOID:9352 (biomarker_via_orthology)
Disease	Infiltrating duct carcinoma of female breast	ATR EPHA8	3.33e-03	21	121	2	C3165106
Disease	multiple sclerosis (is_implicated_in)	KIF1B NDUFS2 IL2RA	3.39e-03	73	121	3	DOID:2377 (is_implicated_in)
Disease	Seckel syndrome	ATR ATRIP	3.65e-03	22	121	2	C0265202
Disease	hypertrophic cardiomyopathy (is_implicated_in)	NDUFS2 CS	3.65e-03	22	121	2	DOID:11984 (is_implicated_in)
Disease	sciatic neuropathy (implicated_via_orthology)	HMOX1 MTOR	3.99e-03	23	121	2	DOID:11446 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LISDWISSNRNRIPL	TRHDE	836	Q9UKU6
VLINRSLVERGLAQW	AKAP1	881	Q92667
RVGWELLLTTIARTI	ACTN2	721	P35609
IASLQNRIDWGRSQL	CCDC115	151	Q96NT0
SLRNLISQGWAVNII	ASB9	51	Q96DX5
LVGVTGQSVWLQLLR	CATSPER2	196	Q96P56
GQSVWLQLLRICRVL	CATSPER2	201	Q96P56
QRLLWTLESLVTGRA	ALDH16A1	116	Q8IZ83
ILNSASVTNWTVLLR	ADGRF1	381	Q5T601
VLIGLTVRWTVSLNS	ALG6	11	Q9Y672
QLNRQSILIGSRCLW	DYNLT5	136	Q8N7M0
GLRVVRQWLEASSQL	ABHD16A	466	O95870
LVLLRTWGLQATNAV	COQ6	441	Q9Y2Z9
IRSLNIQWLRDQIGI	ABCB11	486	O95342
RLLQLWVSAVQSSIA	ACAP1	346	Q15027
PQAWLLRRQSRALLS	DNHD1	4401	Q96M86
RALLSALQRSSPVWV	DNHD1	4411	Q96M86
WNSLQLRGLVVLLIS	PDSS2	106	Q86YH6
SARVRQTWSVLLLLL	CCKBR	211	P32239
TQTLTAWQGLRLQER	GRAMD1B	656	Q3KR37
NRALIITGSWLNEIL	ATP8B1	796	O43520
RLTTTRNAVWALSNL	KPNA5	226	O15131
RTQGSLRLILNTKLW	RANBP3	446	Q9H6Z4
RNQWSVSRPLLGLIL	RANBP17	996	Q9H2T7
SRTLVRLQLWDIAGQ	RAB32	71	Q13637
TLRNRVWLLSFGSVS	KIAA0100	811	Q14667
RLSGVVTSRLNLWIS	LAD1	466	O00515
RSLTTLSEQWIILRN	MDN1	4241	Q9NU22
IWSLQTRRAVTTLDG	GNB1L	51	Q9BYB4
LTSIWTTRLLVQGSL	LYVE1	11	Q9Y5Y7
LLLNRIRTWQKTHQG	LAMA3	2001	Q16787
KAITRILWLTTRQGL	LLGL2	281	Q6P1M3
QRWSLAEIIGITRQL	LRRC37A2	156	A6NM11
QRWSLAEIIGITRQL	LRRC37A	156	A6NMS7
NRVTRVAWLNRSTIL	NTM	61	Q9P121
RIRIFWLLHTSGTQN	HCAR2	251	Q8TDS4
LTWLLRENLGGNSRT	KIF1B	311	O60333
TRVAREQGTVLLLWS	IL17RE	546	Q8NFR9
PNTRRLTVSTWLLRQ	LPAR1	111	Q92633
LTVSTWLLRQGLIDT	LPAR1	116	Q92633
RLQQVLSWARPSEAL	PNMA6E	451	A0A0J9YXQ4
LRQGLTVLTWSSLTL	DNAH8	676	Q96JB1
SILSGTELQARWVTR	FMO4	376	P31512
PTLASLQRLLWVRQA	DUSP13	26	Q9UII6
LLQRLQSLWATGRLD	NOD1	211	Q9Y239
TLTVNRWFLRQGLLD	LPAR3	96	Q9UBY5
GESLWLNLRNRISQQ	MYLIP	51	Q8WY64
RQQLGSRLAWTLTAN	TUBGCP3	196	Q96CW5
ITSNRWLAIRLELVG	ABCC2	1201	Q92887
GQLRRLQELRTIWLS	LRRC10	161	Q5BKY1
LQELRTIWLSGNRLT	LRRC10	166	Q5BKY1
RRLSWGSTAVQLFIL	PGAP4	16	Q9BRR3
ATWNRESLLLQVRGS	MRPL37	211	Q9BZE1
ITNTGLLLIAWGLQR	FBXL14	156	Q8N1E6
ATRILQRLWGTQDVS	SLC2A14	246	Q8TDB8
WVIRSLLSILQRSSE	HUWE1	3221	Q7Z6Z7
SQVVWALIASRGQRL	NANOS2	16	P60321
LLTNNRIWRNRTIDI	NDUFS2	261	O75306
RRINSINQVLLAWTL	OR56B2P	201	Q8NGI1
LALWTLGIISRQARL	SLC51A	231	Q86UW1
SRWLRASQPQALLVI	QRFP	56	P83859
NGSRSQQWLLRNVTL	GALNT1	541	Q10472
NWIITRLLRIAATPS	ATR	101	Q13535
GLALSSLRLRNVSWA	CD14	141	P08571
TRAWRTSLLIALGTL	IL3RA	301	P26951
RLSLQRTQAGWLLLG	HEATR5B	546	Q9P2D3
IIRRQPVSLDLSWTN	KDM2B	1121	Q8NHM5
WLRNAVPLISSQRLR	BOC	356	Q9BWV1
RLLTTGVSRWNTRQI	CORO2B	236	Q9UQ03
IDNGIIVSNSRRWAL	DNAH3	3066	Q8TD57
GRILQQHWLGLQTLR	FBXO15	6	Q8NCQ5
LRISNVGSNSARLTW	COL14A1	541	Q05707
ASVLRNRSVLLQWRL	FNDC10	81	F2Z333
ELAQRLSNRILWIGI	ATG9A	281	Q7Z3C6
VSRALGVLAQLIWSR	CS	426	O75390
WSILLDRSQTRLQIV	DPP8	391	Q6V1X1
IRQERAGQTSVSLLW	EPHA8	446	P29322
AWNLLVLATILRVRT	HTR5A	56	P47898
ISVLLLSGLTWQRRQ	IL2RA	251	P01589
SRTLWLPLTALRNRN	MARCHF11	341	A6NNE9
RSLNLKSLLQWVTSR	FNTB	266	P49356
LGVRLQAGLRAWTQV	DYNC1H1	911	Q14204
GLQELWLNRTQLRTL	GP5	291	P40197
TRSQAPLLRWVLTLS	HMOX1	261	P09601
WRQRSNTQGSILINL	ATRIP	301	Q8WXE1
IQSIWSRLQETGLLS	HDAC5	711	Q9UQL6
IQSIWSRLQETGLLN	HDAC9	661	Q9UKV0
IRSWRTLAILVNLQG	SLC22A15	221	Q8IZD6
FRLLRGWLQSLVQDT	DSEL	916	Q8IZU8
LNRQWTSSLVLGVIT	NEURL4	1181	Q96JN8
ISWGTLAVLALQLAR	DELE1	86	Q14154
LTWLLRENLGGNSRT	KIF1A	311	Q12756
RGNNLQDTLRVLTLW	MTOR	1896	P42345
SINTTRVRLNLIGWN	DSCAM	1486	O60469
WRTLSLIRTRAVTQV	MRPS15	6	P82914
SIILRLPWLNRSQTV	RRN3	111	Q9NYV6
QILTALVVSRIGLLW	TAS2R19	46	P59542
QIIAALAVSRVGLLW	TAS2R20	46	P59543
QILTALAVSRVGLLW	TAS2R30	46	P59541
QILTALAVSRVGLLW	TAS2R31	46	P59538
QILTALVVSRVGLLW	TAS2R33	46	P0DSN6
QILTALVVSRVGLLW	TAS2R36	46	P0DTE0
QILTALAVSRVGLLW	TAS2R43	46	P59537
QIVTALAVSRVGLLW	TAS2R45	46	P59539
QILTALAVSRVGLLW	TAS2R46	46	P59540
LAVSRVGLLWVLVLN	TAS2R46	51	P59540
QILTALAVSRIGLLW	TAS2R50	46	P59544
RTSSWLVLRNLTPQI	TNRC6C	1511	Q9HCJ0
RWVTGQLSLTSLSLR	SNAP47	66	Q5SQN1
KLTLLSNQWQGVIRR	SYNE1	7536	Q8NF91
ARLLCSWQLRTILSG	FANCL	51	Q9NW38
WLRGLLTSRQSFNII	FANCL	341	Q9NW38
RGWLRKLSAVVQLSL	LMF2	391	Q9BU23
VQLLSGVVWLIRNGS	NAGPA	196	Q9UK23
WTSRGRQLRQCLSLV	SLF2	1006	Q8IX21
TLWRQLQSRLLSTDS	URB1	1301	O60287
ISINIVTLLWSRFRG	SPEM1	41	Q8N4L4
RLQLTWLENGNVSRT	SIRPB1	281	Q5TFQ8
RTATLVISLARGWQQ	ABRA	21	Q8N0Z2
SLLTNQTLWRTEGRQ	ADGRE3	141	Q9BY15
AWRIQRLKSGQTALI	LINC01559	101	Q495D7
LSRSVLRWLQGLDLS	SPATA4	51	Q8NEY3
GSQAVQLTSRRWLNL	SUCLG2	26	Q96I99
WLLQQRGADISLQVR	WDR90	1276	Q96KV7
LIANRTQQGVLLSWL	IGSF9B	621	Q9UPX0
STWINQVRRRSSLLG	STAR	46	P49675
WTAENRLLRLLQLNG	WDR97	716	A6NE52
WIVVSQLRITSLQLS	AXL	96	P30530
LAQLLTLARWIQTVL	UBR1	1226	Q8IWV7
TLARWIQTVLARISG	UBR1	1231	Q8IWV7
SIILRLPWLNRSQTV	RRN3P2	111	A6NIE6
LLSFLRRWNGSTAIT	TREM2	71	Q9NZC2
GVSLVILWLQLARVN	TRAV17	6	A0A0B4J275
ITLIGPSISSWRLQR	VSIG10L	666	Q86VR7
ATNVVRLLLGSTALW	UGGT2	6	Q9NYU1
RVTSAGLTLQDLQLW	UNQ5830/PRO19650/PRO19816	66	Q6UY13
ISQLQVLRGSAVLWA	SLC27A6	236	Q9Y2P4
LSQWLRQRPTIGLFT	SLIT1	226	O75093
RFRRQLALLTWTLQG	TFR2	771	Q9UP52
WLAQGRVTIRLSSNL	ZAN	1631	Q9Y493
TILRNLLENSGWITQ	GLDC	146	P23378