Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of osteoclast differentiation

POU4F1 POU4F2 LTF MTOR

1.51e-05116274GO:0045670
GeneOntologyBiologicalProcessosteoclast differentiation

POU4F1 POU4F2 LTF MTOR

5.59e-05162274GO:0030316
GeneOntologyBiologicalProcessregulation of myeloid leukocyte differentiation

POU4F1 POU4F2 LTF MTOR

8.78e-05182274GO:0002761
GeneOntologyBiologicalProcessneuromuscular process controlling balance

POU4F1 POU4F2 POU4F3

1.22e-0474273GO:0050885
MousePhenoabnormal embryonic neuroepithelium morphology

COLGALT1 MTOR WDPCP APAF1

1.63e-05105214MP:0004261
MousePhenoabsent embryonic telencephalon

MTOR PCSK6

4.49e-057212MP:0013906
MousePhenoabnormal midbrain morphology

POU4F1 POU4F2 MTOR APAF1

6.79e-05151214MP:0000897
MousePhenosmall cochlear ganglion

POU4F1 POU4F3

2.88e-0417212MP:0003986
MousePhenoabnormal brainstem morphology

POU4F1 POU4F2 MTOR APAF1

3.26e-04227214MP:0005277
MousePhenoabnormal retina outer nuclear layer morphology

MACF1 POU4F2 CACNA2D4 SYNE2

4.03e-04240214MP:0003731
MousePhenoabnormal retina neuronal layer morphology

MACF1 POU4F2 CACNA2D4 SYNE2 APAF1

4.09e-04441215MP:0006069
MousePhenoabnormal somatic sensory system morphology

MACF1 POU4F1 POU4F2 POU4F3 WDPCP SYNE2

4.45e-04702216MP:0000959
MousePhenoabnormal vestibular ganglion morphology

POU4F1 POU4F3

5.82e-0424212MP:0002856
MousePhenoabnormal nasal cartilage morphology

PCSK6 CDON

6.32e-0425212MP:0031449
MousePhenothin retina outer plexiform layer

CACNA2D4 SYNE2

7.38e-0427212MP:0008519
MousePhenoabnormal retina layer morphology

MACF1 POU4F2 CACNA2D4 SYNE2 APAF1

7.52e-04504215MP:0003727
MousePhenoabnormal telencephalon development

MTOR PCSK6 APAF1

8.45e-04126213MP:0000934
MousePhenoabnormal embryonic tissue morphology

MACF1 COLGALT1 MTOR WDPCP PCSK6 CDON APAF1

8.69e-041116217MP:0002085
MousePhenothin retina outer nuclear layer

MACF1 POU4F2 SYNE2

8.84e-04128213MP:0008515
MousePhenoabnormal retina outer nuclear layer thickness

MACF1 POU4F2 SYNE2

9.04e-04129213MP:0011997
MousePhenoabnormal palate morphology

COLGALT1 WDPCP CDON APAF1

1.20e-03321214MP:0003755
MousePhenoabnormal stationary movement

POU4F1 POU4F2 POU4F3

1.32e-03147213MP:0001388
MousePhenoabnormal neural tube morphology

COLGALT1 MTOR WDPCP CDON APAF1

1.54e-03591215MP:0002151
MousePhenodecreased fibroblast cell migration

WDPCP SYNE2

1.54e-0339212MP:0011708
MousePhenothin retina inner nuclear layer

POU4F2 SYNE2

1.62e-0340212MP:0008511
DomainPOU

POU4F1 POU4F2 POU4F3

1.33e-0616263SM00352
DomainPOU_2

POU4F1 POU4F2 POU4F3

1.33e-0616263PS00465
DomainPou

POU4F1 POU4F2 POU4F3

1.33e-0616263PF00157
DomainPOU_dom

POU4F1 POU4F2 POU4F3

1.33e-0616263IPR000327
DomainPOU_3

POU4F1 POU4F2 POU4F3

1.33e-0616263PS51179
DomainPOU_1

POU4F1 POU4F2 POU4F3

1.33e-0616263PS00035
DomainPOU

POU4F1 POU4F2 POU4F3

1.61e-0617263IPR013847
Domain-

POU4F1 POU4F2 POU4F3

6.85e-06272631.10.260.40
DomainLambda_DNA-bd_dom

POU4F1 POU4F2 POU4F3

8.54e-0629263IPR010982
DomainActinin_actin-bd_CS

MACF1 SYNE2

4.63e-0423262IPR001589
DomainACTININ_2

MACF1 SYNE2

4.63e-0423262PS00020
DomainACTININ_1

MACF1 SYNE2

4.63e-0423262PS00019
DomainSpectrin

MACF1 SYNE2

4.63e-0423262PF00435
Domain-

POU4F1 POU4F2 POU4F3 TTF1

5.93e-042832641.10.10.60
DomainSpectrin_repeat

MACF1 SYNE2

7.39e-0429262IPR002017
DomainSpectrin/alpha-actinin

MACF1 SYNE2

9.01e-0432262IPR018159
DomainSPEC

MACF1 SYNE2

9.01e-0432262SM00150
DomainHomeodomain-like

POU4F1 POU4F2 POU4F3 TTF1

1.08e-03332264IPR009057
DomainHomeobox_CS

POU4F1 POU4F2 POU4F3

2.13e-03186263IPR017970
Domainig

KIR2DL1 KIR2DL2 CDON

2.27e-03190263PF00047
DomainImmunoglobulin

KIR2DL1 KIR2DL2 CDON

2.27e-03190263IPR013151
DomainCH

MACF1 SYNE2

3.67e-0365262SM00033
DomainHomeobox

POU4F1 POU4F2 POU4F3

4.08e-03234263PF00046
DomainHOMEOBOX_1

POU4F1 POU4F2 POU4F3

4.18e-03236263PS00027
DomainHOX

POU4F1 POU4F2 POU4F3

4.23e-03237263SM00389
DomainCH

MACF1 SYNE2

4.25e-0370262PF00307
DomainHomeobox_dom

POU4F1 POU4F2 POU4F3

4.33e-03239263IPR001356
DomainHOMEOBOX_2

POU4F1 POU4F2 POU4F3

4.33e-03239263PS50071
Domain-

MACF1 SYNE2

4.37e-03712621.10.418.10
DomainCH

MACF1 SYNE2

4.61e-0373262PS50021
DomainCH-domain

MACF1 SYNE2

4.86e-0375262IPR001715
DomainWD_REPEATS_1

WDPCP DTL APAF1

6.58e-03278263PS00678
DomainWD_REPEATS_2

WDPCP DTL APAF1

6.65e-03279263PS50082
DomainWD_REPEATS_REGION

WDPCP DTL APAF1

6.65e-03279263PS50294
DomainWD40_repeat_dom

WDPCP DTL APAF1

7.90e-03297263IPR017986
PathwayWP_MECP2_AND_ASSOCIATED_RETT_SYNDROME

POU4F1 MTOR CDON

1.91e-0473223M39401
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

POU4F1 POU4F2

2.09e-0414222M27638
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

POU4F1 POU4F2

2.09e-0414222MM15341
Pubmed

Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems.

POU4F1 POU4F2 POU4F3

4.67e-1032839598366
Pubmed

Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse.

POU4F1 POU4F2 POU4F3

4.67e-10328321935940
Pubmed

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.

POU4F1 POU4F2 POU4F3

4.67e-1032838290353
Pubmed

The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons.

POU4F1 POU4F2 POU4F3

4.67e-1032837623109
Pubmed

Systematic identification of intergenic long-noncoding RNAs in mouse retinas using full-length isoform sequencing.

POU4F1 POU4F2 POU4F3

4.67e-10328331286854
Pubmed

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.

POU4F1 POU4F2 POU4F3

4.67e-1032837935408
Pubmed

Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.

POU4F1 POU4F2 POU4F3

4.67e-1032838162704
Pubmed

Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.

POU4F1 POU4F2 POU4F3

1.87e-0942839256502
Pubmed

Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.

POU4F1 POU4F2 POU4F3

1.87e-09428333135183
Pubmed

Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.

POU4F1 POU4F2 POU4F3

1.87e-09428320826176
Pubmed

Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.

POU4F1 POU4F2 POU4F3

1.87e-09428324116103
Pubmed

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.

POU4F1 POU4F2 POU4F3

4.67e-0952838637595
Pubmed

The Wilms' tumor gene Wt1 is required for normal development of the retina.

POU4F1 POU4F2 POU4F3

9.33e-09628311889045
Pubmed

Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion.

POU4F1 POU4F2 POU4F3

9.33e-09628320533399
Pubmed

Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors.

POU4F1 POU4F2 POU4F3

9.33e-0962839630743
Pubmed

POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells.

POU4F1 POU4F2 POU4F3

9.33e-0962838632990
Pubmed

Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis.

POU4F1 POU4F2 POU4F3

9.33e-09628322262898
Pubmed

Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth.

POU4F1 POU4F2 POU4F3

9.33e-09628311807038
Pubmed

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells.

POU4F1 POU4F2 POU4F3

1.63e-0872839735355
Pubmed

RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.

POU4F1 POU4F2 POU4F3

5.59e-081028323805044
Pubmed

Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling.

POU4F1 POU4F2 POU4F3

7.68e-08112838876243
Pubmed

Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.

POU4F1 POU4F2 POU4F3

7.68e-08112838955272
Pubmed

The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells.

POU4F1 POU4F2 POU4F3

7.68e-081128328009286
Pubmed

Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina.

POU4F1 POU4F2 POU4F3

1.02e-071228321771810
Pubmed

Integral bHLH factor regulation of cell cycle exit and RGC differentiation.

POU4F1 POU4F2 POU4F3

2.11e-071528329770538
Pubmed

Brn3a and Brn3b knockout mice display unvaried retinal fine structure despite major morphological and numerical alterations of ganglion cells.

POU4F1 POU4F2

6.25e-07228227391320
Pubmed

Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding.

POU4F1 POU4F2

6.25e-0722828537352
Pubmed

Brn3 transcription factors control terminal osteoclastogenesis.

POU4F1 POU4F2

6.25e-07228217668438
Pubmed

Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor.

POU4F1 POU4F2

6.25e-0722828995448
Pubmed

Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells.

POU4F1 POU4F2

6.25e-0722828234287
Pubmed

KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals.

KIR2DL1 KIR2DL2

6.25e-07228231519864
Pubmed

POU4F3 Is Necessary for Normal Merkel Cell Formation, whereas POU4F1 Is Dispensable.

POU4F1 POU4F3

6.25e-07228239009281
Pubmed

A single amino acid change converts an inhibitory transcription factor into an activator.

POU4F1 POU4F2

6.25e-0722828662774
Pubmed

Autoregulatory sequences are revealed by complex stability screening of the mouse brn-3.0 locus.

POU4F1 POU4F2

6.25e-07228210414983
Pubmed

Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid.

POU4F1 POU4F2

6.25e-0722827904822
Pubmed

NT-3 regulates expression of Brn3a but not Brn3b in developing mouse trigeminal sensory neurons.

POU4F1 POU4F2

6.25e-0722829582431
Pubmed

Differential expression and subcellular localization of Copines in mouse retina.

POU4F1 POU4F2

6.25e-07228230866042
Pubmed

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.

POU4F1 POU4F3

6.25e-0722828248179
Pubmed

Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.

POU4F1 POU4F2 POU4F3

7.12e-072228322326227
Pubmed

Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina.

POU4F1 POU4F2 POU4F3

1.06e-062528322411557
Pubmed

Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression.

POU4F1 POU4F2

1.87e-06328217145718
Pubmed

No association between POU4F1, POU4F2, ISL1 polymorphisms and normal-tension glaucoma.

POU4F1 POU4F2

1.87e-06328232597291
Pubmed

Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors.

POU4F1 POU4F2

1.87e-06328215094508
Pubmed

Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors.

KIR2DL1 KIR2DL2

1.87e-06328215879158
Pubmed

Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.

POU4F1 POU4F2

1.87e-06328224736625
Pubmed

Pou4f2-GFP knock-in mouse line: A model for studying retinal ganglion cell development.

POU4F1 POU4F2

1.87e-06328227532212
Pubmed

POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element.

POU4F1 POU4F2

1.87e-0632829448000
Pubmed

Dre - Cre sequential recombination provides new tools for retinal ganglion cell labeling and manipulation in mice.

POU4F1 POU4F2

1.87e-06328224608965
Pubmed

Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells.

POU4F1 POU4F2

1.87e-06328219323995
Pubmed

[Effect of demethylation treatment on the expression of inhibitory receptor KIR gene in NK-92MI cell line].

KIR2DL1 KIR2DL2

1.87e-06328219549382
Pubmed

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1.

POU4F1 POU4F2 POU4F3

2.07e-063128316702404
Pubmed

B-lymphoma cells escape rituximab-triggered elimination by NK cells through increased HLA class I expression.

KIR2DL1 KIR2DL2

3.75e-06428220056126
Pubmed

HLA-C and KIR genes in hepatitis C virus infection.

KIR2DL1 KIR2DL2

3.75e-06428216571411
Pubmed

[Analysis of HLA-Cw, KIR2D genetic variations in 2 Chinese populations].

KIR2DL1 KIR2DL2

3.75e-06428218543232
Pubmed

Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general.

KIR2DL1 KIR2DL2

3.75e-06428225037176
Pubmed

[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].

KIR2DL1 KIR2DL2

3.75e-06428218269867
Pubmed

Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).

KIR2DL1 KIR2DL2

3.75e-06428226542066
Pubmed

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.

POU4F1 POU4F2 CDON

4.53e-064028334677125
Pubmed

Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression.

POU4F1 POU4F2

6.24e-06528218368538
Pubmed

Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.

KIR2DL1 KIR2DL2

6.24e-06528216112031
Pubmed

Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters.

KIR2DL1 KIR2DL2

6.24e-06528212121272
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DL1 KIR2DL2

6.24e-06528218755860
Pubmed

Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding.

POU4F1 POU4F2

6.24e-06528235988153
Pubmed

New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling.

POU4F1 POU4F2

6.24e-06528219924248
Pubmed

Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.

KIR2DL1 KIR2DL2

6.24e-06528218322206
Pubmed

The emergence of transcriptional identity in somatosensory neurons.

POU4F2 POU4F3

6.24e-06528231915380
Pubmed

Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.

POU4F1 POU4F2 POU4F3

8.40e-064928331609468
Pubmed

Expression of a large family of POU-domain regulatory genes in mammalian brain development.

POU4F1 POU4F2

9.36e-0662822739723
Pubmed

Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart.

POU4F1 POU4F2

9.36e-06628228594399
Pubmed

Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus.

POU4F1 POU4F3

9.36e-06628227259519
Pubmed

Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.

POU4F1 POU4F2 POU4F3

1.07e-055328327210758
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MACF1 MRTO4 LTF TTF1 MTOR SYNE2

1.13e-0565328622586326
Pubmed

Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc.

POU4F2 CDON

1.31e-05728220053908
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DL1 KIR2DL2

1.31e-05728214607943
Pubmed

Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development.

POU4F1 POU4F2

1.31e-05728226962139
Pubmed

Class I histone deacetylases in retinal progenitors and differentiating ganglion cells.

POU4F1 POU4F3

1.31e-05728230179675
Pubmed

Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons.

POU4F1 POU4F2

1.31e-05728224709358
Pubmed

Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.

KIR2DL1 KIR2DL2

1.31e-05728211169255
Pubmed

mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase.

MTOR DTL

1.74e-05828218235224
Pubmed

Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy.

KIR2DL1 KIR2DL2

1.74e-05828220935224
Pubmed

Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.

POU4F2 CDON

1.74e-05828223678105
Pubmed

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.

KIR2DL1 KIR2DL2

1.74e-05828215730517
Pubmed

Brn3a controls the soma localization and axonal extension patterns of developing spinal dorsal horn neurons.

POU4F1 POU4F2

1.74e-05828237733805
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DL1 KIR2DL2

1.74e-05828218681957
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DL1 KIR2DL2

2.24e-0592827749980
Pubmed

Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.

POU4F1 POU4F2

2.24e-05928230995485
Pubmed

Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7.

POU4F1 POU4F2

2.24e-05928223293286
Pubmed

Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections.

POU4F1 POU4F2

2.24e-05928237590135
Pubmed

Chromosomal organization of mammalian POU domain factors.

POU4F1 POU4F2

2.24e-0592828276396
Pubmed

Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells.

POU4F2 POU4F3

2.24e-05928224643061
Pubmed

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system.

POU4F1 POU4F2

2.24e-05928215716344
Pubmed

Characterization of retinal ganglion cell, horizontal cell, and amacrine cell types expressing the neurotrophic receptor tyrosine kinase Ret.

POU4F1 POU4F2

2.80e-051028229218725
Pubmed

Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons.

POU4F1 POU4F2

2.80e-051028211493560
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DL1 KIR2DL2

2.80e-051028212559621
Pubmed

Natural killer cells and immune surveillance.

KIR2DL1 KIR2DL2

3.42e-051128218830515
Pubmed

Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina.

POU4F1 POU4F2

3.42e-051128228356311
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DL1 KIR2DL2

3.42e-051128219664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DL1 KIR2DL2

4.10e-051228220371502
Pubmed

Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways.

POU4F1 POU4F2

4.10e-051228216354917
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DL1 KIR2DL2

4.10e-051228219181658
Cytoband19q13.4

KIR2DL1 KIR2DL2

1.07e-037928219q13.4
CytobandEnsembl 112 genes in cytogenetic band chr5q32

POU4F3 IL17B

1.10e-0380282chr5q32
CytobandEnsembl 112 genes in cytogenetic band chr12q23

PARPBP APAF1

3.79e-03150282chr12q23
GeneFamilyPOU class homeoboxes and pseudogenes

POU4F1 POU4F2 POU4F3

3.13e-0623233523
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DL1 KIR2DL2

2.34e-0418232620
CoexpressionAtlasB cells, proB.FrA.BM, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Bone marrow, avg-2

LTF PARPBP SYNE2 KNL1 DTL

6.34e-05388245GSM538352_500
CoexpressionAtlasB cells, B.Pl.AA4-.BM, CD138+ AA4.1- CD43+, Bone marrow, avg-2

LTF PARPBP SYNE2 KNL1 DTL

6.81e-05394245GSM777030_500
CoexpressionAtlasB cells, proB.FrA.BM, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Bone marrow, avg-2

LTF KNL1 DTL

1.35e-0489243GSM538352_100
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#3_top-relative-expression-ranked_1000

POU4F1 PCSK6 SYNE2

1.54e-0493243gudmap_developingGonad_e16.5_ovary_1000_k3
ToppCellControl-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

POU4F3 KIR2DL2 LAYN DTL

9.38e-07120284695dab6b01ad2c33cdcaf92bb9996ff2899ef77e
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

KIR2DL1 KIR2DL2 SYNE2 KNL1

2.88e-0615928497c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

KIR2DL1 KIR2DL2 SYNE2 KNL1

2.88e-06159284fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PARPBP SYNE2 KNL1 DTL

4.12e-06174284b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PARPBP SYNE2 KNL1 DTL

4.12e-0617428494575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PARPBP SYNE2 KNL1 DTL

4.12e-0617428440c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

LTF SYNE2 KNL1 DTL

7.00e-06199284f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

MACF1 KIR2DL1 KIR2DL2 SYNE2

7.00e-06199284e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

LTF SYNE2 KNL1 DTL

7.00e-0619928442ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

MACF1 KIR2DL1 KIR2DL2 SYNE2

7.00e-061992845f914962e2572b0c6372465b81b7496fa663d93c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

PARPBP SYNE2 KNL1 DTL

7.14e-062002848f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

PARPBP SYNE2 KNL1 DTL

7.14e-06200284a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

PARPBP SYNE2 KNL1 DTL

7.14e-06200284971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

PARPBP SYNE2 KNL1 DTL

7.14e-062002840d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

PARPBP SYNE2 KNL1 DTL

7.14e-062002840675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

MRTO4 KNL1 DTL

7.32e-05130283169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCell368C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MIGA1 PCSK6 KNL1

1.10e-041492839286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell368C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MIGA1 PCSK6 KNL1

1.10e-04149283f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

MACF1 POU4F3 SYNE2

1.26e-04156283afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell368C-Fibroblasts-Fibroblast-F-|368C / Donor, Lineage, Cell class and subclass (all cells)

MIGA1 PCSK6 KNL1

1.28e-04157283982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell368C-Fibroblasts-Fibroblast-F|368C / Donor, Lineage, Cell class and subclass (all cells)

MIGA1 PCSK6 KNL1

1.28e-0415728374038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARPBP KNL1 DTL

1.28e-041572830fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PARPBP KNL1 DTL

1.38e-041612830dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PARPBP KNL1 DTL

1.38e-04161283b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PARPBP KNL1 DTL

1.38e-04161283efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PARPBP KNL1 DTL

1.38e-0416128328d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL1 KNL1 DTL

1.43e-04163283466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.48e-04165283eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.51e-041662832642544070564debe2deb2938d2c33997bf5ef02
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.54e-0416728350c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.56e-04168283d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.59e-04169283b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.59e-0416928354b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.62e-0417028321bfe070e63722672176052b386167ea4c3dc4e5
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PARPBP KNL1 DTL

1.62e-0417028373601c873b177d5d134618d8e228c51381119f7d
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

PARPBP KNL1 DTL

1.65e-04171283976361f67dd725870e0513ae7a92f2dcaee17148
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF DNAJB14 APAF1

1.65e-04171283913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF DNAJB14 APAF1

1.65e-04171283f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MACF1 IL17B SYNE2

1.65e-0417128361318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.65e-0417128355c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIR2DL1 KIR2DL2 SYNE2

1.65e-04171283adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

PARPBP KNL1 DTL

1.71e-041732838a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARPBP KNL1 DTL

1.71e-041732832eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.73e-0417428384da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.73e-041742837b318796728001c17b4043d2b033330c7be40c78
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PARPBP KNL1 DTL

1.76e-0417528373f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.76e-04175283f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

KLHL3 LAYN PCSK6

1.79e-04176283c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU4F1 PARPBP DTL

1.79e-041762833e7647364c13beade9ca278c7ce8e89546e0b060
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU4F1 PARPBP DTL

1.79e-04176283a55572470de6af6cbf29ed4f785fdca62d24cd23
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

KLHL3 LAYN PCSK6

1.79e-0417628398c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MACF1 KIR2DL2 SYNE2

1.82e-04177283d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MACF1 KIR2DL2 SYNE2

1.82e-04177283f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MACF1 KIR2DL2 SYNE2

1.82e-04177283936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MACF1 KIR2DL2 SYNE2

1.82e-04177283d5aeda113afaa2425874394610344570c9078478
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

MACF1 KIR2DL2 SYNE2

1.82e-041772836978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.89e-0417928388d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARPBP KNL1 DTL

1.89e-04179283804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

1.92e-04180283401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MACF1 PCSK6 SYNE2

1.92e-04180283493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellASK428-Immune-NK_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

KIR2DL1 KIR2DL2 SYNE2

1.92e-04180283857d09446e3e6737e83d0f10bfda2ba282d5ba75
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D4 TTF1 DTL

1.92e-0418028387347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PARPBP KNL1 DTL

1.95e-041812830c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF SYNE2 KNL1

1.95e-04181283566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAYN PARPBP KNL1

1.95e-04181283b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PARPBP KNL1 DTL

1.95e-04181283f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF SYNE2 KNL1

1.95e-04181283db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAYN PARPBP KNL1

1.95e-04181283c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PARPBP KNL1 DTL

1.95e-0418128373b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PARPBP KNL1 DTL

1.98e-04182283f703963b5d1e8c1f95d78807521048553b0792d8
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF SYNE2 KNL1

1.98e-04182283c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|World / disease group, cell group and cell class (v2)

PARPBP KNL1 DTL

1.98e-041822839adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

PARPBP KNL1 DTL

1.98e-0418228381557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCellsevere-multiplets|World / disease stage, cell group and cell class

PARPBP KNL1 DTL

1.98e-041822835e30ec7120a988d9ee3000513e1209618f28f5f9
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF SYNE2 KNL1

1.98e-041822839025178ede571e3808d4657ad4892152f336c9b4
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTF KNL1 DTL

1.98e-0418228311494a66d986297b837332ee9d382b71b9f22591
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PARPBP KNL1 DTL

1.98e-04182283ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCellsevere-multiplets|severe / disease stage, cell group and cell class

PARPBP KNL1 DTL

2.01e-0418328378af8df48f0fe49ac37ccec0ad7b2993883b1148
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

PARPBP KNL1 DTL

2.01e-04183283a48a6313f2f144586951cece97ec31f6d72361df
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

PARPBP KNL1 DTL

2.01e-0418328309c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARPBP KNL1 DTL

2.01e-04183283769a022fe8568ec49e66f792cc5777e713a7571c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARPBP KNL1 DTL

2.01e-04183283aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PARPBP KNL1 DTL

2.01e-04183283df8568751205313d149939ea2683097e3652a60b
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|lung / Disease (COVID-19 only), tissue and cell type

PARPBP KNL1 DTL

2.04e-04184283480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

KLHL3 LAYN PCSK6

2.04e-0418428303ea613e00b45c81b752c14505a0538d698f551e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PARPBP KNL1 DTL

2.04e-04184283a0831e850bc0b585296ed350fdd075c1f730308e
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

MACF1 KIR2DL2 SYNE2

2.04e-04184283791f1bcb954aadc63d4117c400537d036f68734d
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PARPBP KNL1 DTL

2.08e-0418528389b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

PARPBP KNL1 DTL

2.08e-041852839766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

2.08e-0418528330e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

PARPBP KNL1 DTL

2.08e-041852830ae9c646679c69a553eda670aef0e0495feb0286
ToppCell3'_v3-blood-Lymphocytic_T_CD4/8-lo|blood / Manually curated celltypes from each tissue

PARPBP KNL1 DTL

2.08e-04185283df85ff34b796b403f2d0741771e9592e03657f6a
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

KLHL3 LAYN PCSK6

2.08e-0418528336ce23893915f5c380cca39b2c33a516edf31c3a
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PARPBP KNL1 DTL

2.08e-041852830e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

KLHL3 LAYN PCSK6

2.08e-041852834a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

PARPBP KNL1 DTL

2.11e-0418628366676d9395172de5707e204826a1c9f73b448cca
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|343B / Donor, Lineage, Cell class and subclass (all cells)

KLHL3 LAYN PCSK6

2.11e-041862837a8da2ad140bea3207bd868212cc5e201d586772
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|343B / Donor, Lineage, Cell class and subclass (all cells)

KLHL3 LAYN PCSK6

2.11e-04186283dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

MIGA1 WDPCP KNL1

2.14e-04187283714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PARPBP KNL1 DTL

2.14e-041872839351fa87b69a951af85b10bf91fe9b1cce8c0517
Drug6-carboxyfluorescein diacetate

KIR2DL1 KIR2DL2 MTOR

6.61e-0630283CID000151095
DiseasePapillary Renal Cell Carcinoma

MTOR SYNE2 APAF1

2.16e-04128273C1306837
DiseaseRenal Cell Carcinoma

MTOR SYNE2 APAF1

2.16e-04128273C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

MTOR SYNE2 APAF1

2.16e-04128273C1266043
DiseaseChromophobe Renal Cell Carcinoma

MTOR SYNE2 APAF1

2.16e-04128273C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

MTOR SYNE2 APAF1

2.16e-04128273C1266044
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

MTOR SYNE2 APAF1

3.31e-04148273C0279702
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

MACF1 PCSK6 SYNE2

3.44e-04150273EFO_0004611, EFO_0020947
Diseasecervical cancer

POU4F1 MTOR

4.44e-0434272C4048328
DiseaseUterine Cervical Neoplasm

POU4F1 MTOR

4.71e-0435272C0007873
Diseasecolon cancer (biomarker_via_orthology)

MTOR APAF1

5.85e-0439272DOID:219 (biomarker_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

MACF1 PCSK6 SYNE2

7.96e-04200273EFO_0004611, EFO_0020945
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

MACF1 PCSK6 SYNE2

1.08e-03222273EFO_0008317, EFO_0020943
DiseaseIGFBP-3 measurement

LAYN UNC79

1.12e-0354272EFO_0004626
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

MACF1 PCSK6 SYNE2

1.77e-03264273EFO_0008317, EFO_0020944
Diseasebody surface area

MACF1 UNC79 MTOR DTL

2.63e-03643274EFO_0022196

Protein segments in the cluster

PeptideGeneStartEntry
EAKVQTRNWMQCKSK

TTF1

726

Q15361
KLWDLNQKECRNTMF

APAF1

726

O14727
RFNKIINNMWKQQCG

GVINP1

1981

Q7Z2Y8
RDGNIMVWDTRCNKK

DTL

161

Q9NZJ0
DMIKEFRKNWRALCN

PARPBP

11

Q9NWS1
VWFCNQRQKQKRMKF

POU4F1

401

Q01851
RWCSNKKNAAVMDQE

KIR2DL2

266

P43627
QRKCEVNLQLWMSNK

IL17B

81

Q9UHF5
WNDDRCNMKNNFICK

LAYN

171

Q6UX15
KNSRCRSEMNVQAAW

PCSK6

176

P29122
ENKMGKTCNSQKRTW

KNL1

1776

Q8NG31
KLLETKWNFMQQQRC

KRT82

146

Q9NSB4
SRLKDCMQKAQKYQW

MACF1

4901

Q9UPN3
MQNSRCVLSKWKNKY

WDPCP

111

O95876
NCWKERQQKTDMQYA

DNAJB14

331

Q8TBM8
VSFADRMKWIACNNK

CACNA2D4

436

Q7Z3S7
MCLWKNRQQNTIQKY

CDON

986

Q4KMG0
TWKQVADMNMCRRNA

KLHL3

516

Q9UH77
WDRAKSQKMREQQAL

COLGALT1

586

Q8NBJ5
RWCSNKKNAAVMDQE

KIR2DL1

266

P43626
ANMRNSKLKDIRNAW

MRTO4

46

Q9UKD2
WVLKCRNSKNSLIQM

MTOR

376

P42345
ASSCWSVLKQKRQQM

MIGA1

506

Q8NAN2
TKCFQWQRNMRKVRG

LTF

36

P02788
KCSKVQARWQMSARK

SYNE2

171

Q8WXH0
VWFCNQRQKQKRMKY

POU4F2

391

Q12837
WFCNQRQKQKRMKYS

POU4F3

321

Q15319
ALRKWLQCTQFKMAQ

UNC79

2606

Q9P2D8