| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 2.17e-13 | 26 | 49 | 7 | GO:0005248 | |
| GeneOntologyMolecularFunction | transporter activity | SLC6A2 SLC9A2 SLC37A3 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A PEX2 TCIRG1 DISP2 GRIN2A ATP1A1 TMC3 TTPA ABCA10 DISP1 KCNH3 | 5.93e-13 | 1289 | 49 | 21 | GO:0005215 |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SLC6A2 SLC9A2 SLC37A3 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A PEX2 TCIRG1 DISP2 GRIN2A ATP1A1 TMC3 ABCA10 DISP1 KCNH3 | 1.26e-12 | 1180 | 49 | 20 | GO:0022857 |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | SLC6A2 SLC9A2 SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ATP1A1 | 1.00e-11 | 171 | 49 | 10 | GO:0015081 |
| GeneOntologyMolecularFunction | sodium channel activity | 4.22e-11 | 52 | 49 | 7 | GO:0005272 | |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A ATP1A1 KCNH3 | 6.14e-11 | 465 | 49 | 13 | GO:0046873 |
| GeneOntologyMolecularFunction | sodium ion binding | 1.42e-10 | 14 | 49 | 5 | GO:0031402 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 KCNH3 | 1.92e-10 | 627 | 49 | 14 | GO:0022890 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | SLC6A2 SLC9A2 SLC37A3 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 KCNH3 | 2.02e-10 | 758 | 49 | 15 | GO:0015318 |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 TMC3 KCNH3 | 3.78e-10 | 793 | 49 | 15 | GO:0015075 |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 KCNH3 | 4.06e-10 | 664 | 49 | 14 | GO:0008324 |
| GeneOntologyMolecularFunction | alkali metal ion binding | 4.56e-09 | 26 | 49 | 5 | GO:0031420 | |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A KCNH3 | 8.90e-09 | 343 | 49 | 10 | GO:0005261 |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A TMC3 KCNH3 | 1.11e-08 | 459 | 49 | 11 | GO:0005216 |
| GeneOntologyMolecularFunction | channel activity | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A TMC3 KCNH3 | 4.41e-08 | 525 | 49 | 11 | GO:0015267 |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A TMC3 KCNH3 | 4.50e-08 | 526 | 49 | 11 | GO:0022803 |
| GeneOntologyMolecularFunction | ATPase binding | 6.65e-06 | 108 | 49 | 5 | GO:0051117 | |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | 8.79e-05 | 6 | 49 | 2 | GO:0086006 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | 7.84e-04 | 17 | 49 | 2 | GO:0099508 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 1.03e-03 | 182 | 49 | 4 | GO:0005244 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | 1.05e-03 | 477 | 49 | 6 | GO:0022804 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 1.07e-03 | 184 | 49 | 4 | GO:0022832 | |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | 1.28e-03 | 884 | 49 | 8 | GO:0004930 | |
| GeneOntologyMolecularFunction | gated channel activity | 1.33e-03 | 334 | 49 | 5 | GO:0022836 | |
| GeneOntologyMolecularFunction | ankyrin binding | 1.44e-03 | 23 | 49 | 2 | GO:0030506 | |
| GeneOntologyMolecularFunction | bitter taste receptor activity | 1.99e-03 | 27 | 49 | 2 | GO:0033038 | |
| GeneOntologyMolecularFunction | ATPase-coupled transmembrane transporter activity | 2.43e-03 | 109 | 49 | 3 | GO:0042626 | |
| GeneOntologyMolecularFunction | taste receptor activity | 2.97e-03 | 33 | 49 | 2 | GO:0008527 | |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | OR11H1 ADGRL1 FZD10 TAS2R40 GRIN2A TAS2R60 OR11H2 EDNRB OPRD1 | 5.13e-03 | 1353 | 49 | 9 | GO:0004888 |
| GeneOntologyMolecularFunction | active monoatomic ion transmembrane transporter activity | 6.29e-03 | 301 | 49 | 4 | GO:0022853 | |
| GeneOntologyMolecularFunction | potassium ion transmembrane transporter activity | 7.99e-03 | 167 | 49 | 3 | GO:0015079 | |
| GeneOntologyMolecularFunction | transmembrane transporter binding | 8.66e-03 | 172 | 49 | 3 | GO:0044325 | |
| GeneOntologyMolecularFunction | primary active transmembrane transporter activity | 9.50e-03 | 178 | 49 | 3 | GO:0015399 | |
| GeneOntologyMolecularFunction | ATPase-coupled monoatomic cation transmembrane transporter activity | 1.02e-02 | 62 | 49 | 2 | GO:0019829 | |
| GeneOntologyBiologicalProcess | sodium ion transport | SLC6A2 SLC9A2 SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A NKAIN1 ATP1A1 EDNRB | 1.48e-12 | 275 | 49 | 12 | GO:0006814 |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 1.71e-12 | 62 | 49 | 8 | GO:0086002 | |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 2.16e-12 | 36 | 49 | 7 | GO:0086010 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 2.82e-11 | 87 | 49 | 8 | GO:0086001 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 4.87e-11 | 93 | 49 | 8 | GO:0086003 | |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | SLC6A2 SLC9A2 SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ATP1A1 | 5.11e-11 | 208 | 49 | 10 | GO:0035725 |
| GeneOntologyBiologicalProcess | monoatomic cation transport | SLC6A2 SLC9A2 WFS1 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 NKAIN1 GRIN2A ATP1A1 EDNRB KCNH3 OPRD1 | 5.83e-11 | 1157 | 49 | 18 | GO:0006812 |
| GeneOntologyBiologicalProcess | metal ion transport | SLC6A2 SLC9A2 WFS1 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A NKAIN1 GRIN2A ATP1A1 EDNRB KCNH3 OPRD1 | 5.91e-11 | 1000 | 49 | 17 | GO:0030001 |
| GeneOntologyBiologicalProcess | monoatomic ion transport | SLC6A2 SLC9A2 WFS1 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 NKAIN1 GRIN2A ATP1A1 TMC3 EDNRB KCNH3 OPRD1 | 1.08e-10 | 1374 | 49 | 19 | GO:0006811 |
| GeneOntologyBiologicalProcess | neuronal action potential | 1.37e-10 | 63 | 49 | 7 | GO:0019228 | |
| GeneOntologyBiologicalProcess | actin-mediated cell contraction | 6.03e-10 | 127 | 49 | 8 | GO:0070252 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | SLC6A2 SLC9A2 SLC37A3 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 EDNRB KCNH3 | 7.82e-10 | 1017 | 49 | 16 | GO:0098660 |
| GeneOntologyBiologicalProcess | action potential | 9.72e-10 | 201 | 49 | 9 | GO:0001508 | |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 EDNRB KCNH3 | 1.92e-09 | 922 | 49 | 15 | GO:0098662 |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 EDNRB KCNH3 | 2.58e-09 | 942 | 49 | 15 | GO:0098655 |
| GeneOntologyBiologicalProcess | actin filament-based movement | 2.66e-09 | 153 | 49 | 8 | GO:0030048 | |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | SLC6A2 SLC9A2 SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 TMC3 EDNRB KCNH3 | 2.95e-09 | 1115 | 49 | 16 | GO:0034220 |
| GeneOntologyBiologicalProcess | cardiac muscle contraction | 5.31e-09 | 167 | 49 | 8 | GO:0060048 | |
| GeneOntologyBiologicalProcess | transmission of nerve impulse | 8.20e-09 | 112 | 49 | 7 | GO:0019226 | |
| GeneOntologyBiologicalProcess | membrane depolarization | 1.41e-08 | 121 | 49 | 7 | GO:0051899 | |
| GeneOntologyBiologicalProcess | heart contraction | 3.01e-08 | 298 | 49 | 9 | GO:0060047 | |
| GeneOntologyBiologicalProcess | striated muscle contraction | 4.11e-08 | 217 | 49 | 8 | GO:0006941 | |
| GeneOntologyBiologicalProcess | heart process | 4.11e-08 | 309 | 49 | 9 | GO:0003015 | |
| GeneOntologyBiologicalProcess | regulation of membrane potential | SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A ATP1A1 KCNH3 OPRD1 | 6.02e-08 | 559 | 49 | 11 | GO:0042391 |
| GeneOntologyBiologicalProcess | response to pain | 1.33e-07 | 51 | 49 | 5 | GO:0048265 | |
| GeneOntologyBiologicalProcess | muscle contraction | 3.67e-07 | 400 | 49 | 9 | GO:0006936 | |
| GeneOntologyBiologicalProcess | blood circulation | SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ATP1A1 PLEKHA7 EDNRB | 2.37e-06 | 648 | 49 | 10 | GO:0008015 |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception of pain | 3.24e-06 | 43 | 49 | 4 | GO:0062149 | |
| GeneOntologyBiologicalProcess | muscle system process | 4.85e-06 | 547 | 49 | 9 | GO:0003012 | |
| GeneOntologyBiologicalProcess | circulatory system process | SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ATP1A1 PLEKHA7 EDNRB | 7.07e-06 | 733 | 49 | 10 | GO:0003013 |
| GeneOntologyBiologicalProcess | regulation of monoatomic ion transport | 7.46e-06 | 577 | 49 | 9 | GO:0043269 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus involved in sensory perception | 1.01e-05 | 57 | 49 | 4 | GO:0050974 | |
| GeneOntologyBiologicalProcess | multicellular organismal response to stress | 1.21e-05 | 126 | 49 | 5 | GO:0033555 | |
| GeneOntologyBiologicalProcess | sensory perception of mechanical stimulus | 2.05e-05 | 238 | 49 | 6 | GO:0050954 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus | 3.02e-05 | 75 | 49 | 4 | GO:0050982 | |
| GeneOntologyBiologicalProcess | behavioral response to pain | 5.95e-05 | 32 | 49 | 3 | GO:0048266 | |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | 6.23e-05 | 582 | 49 | 8 | GO:0050906 | |
| GeneOntologyBiologicalProcess | sensory perception of pain | 1.13e-04 | 105 | 49 | 4 | GO:0019233 | |
| GeneOntologyBiologicalProcess | bundle of His cell action potential | 1.15e-04 | 7 | 49 | 2 | GO:0086043 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte signaling | 1.15e-04 | 7 | 49 | 2 | GO:0086028 | |
| GeneOntologyBiologicalProcess | hexose phosphate transport | 1.15e-04 | 7 | 49 | 2 | GO:0015712 | |
| GeneOntologyBiologicalProcess | glucose-6-phosphate transport | 1.15e-04 | 7 | 49 | 2 | GO:0015760 | |
| GeneOntologyBiologicalProcess | regulation of striated muscle contraction | 1.40e-04 | 111 | 49 | 4 | GO:0006942 | |
| GeneOntologyBiologicalProcess | sensory perception | OR11H1 WFS1 SCN1A SCN8A SCN9A SCN10A TAS2R40 GRIN2A TAS2R60 OR11H2 | 1.78e-04 | 1072 | 49 | 10 | GO:0007600 |
| GeneOntologyBiologicalProcess | regulation of pH | 1.89e-04 | 120 | 49 | 4 | GO:0006885 | |
| GeneOntologyBiologicalProcess | behavior | 2.18e-04 | 891 | 49 | 9 | GO:0007610 | |
| GeneOntologyBiologicalProcess | regulation of atrial cardiac muscle cell membrane depolarization | 2.46e-04 | 10 | 49 | 2 | GO:0060371 | |
| GeneOntologyBiologicalProcess | actin filament-based process | 2.59e-04 | 912 | 49 | 9 | GO:0030029 | |
| GeneOntologyBiologicalProcess | detection of stimulus | 2.74e-04 | 722 | 49 | 8 | GO:0051606 | |
| GeneOntologyBiologicalProcess | response to mechanical stimulus | 2.93e-04 | 247 | 49 | 5 | GO:0009612 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell signaling | 3.59e-04 | 12 | 49 | 2 | GO:0086027 | |
| GeneOntologyBiologicalProcess | AV node cell action potential | 3.59e-04 | 12 | 49 | 2 | GO:0086016 | |
| GeneOntologyBiologicalProcess | cell communication involved in cardiac conduction | 3.73e-04 | 59 | 49 | 3 | GO:0086065 | |
| GeneOntologyBiologicalProcess | odontogenesis | 4.53e-04 | 151 | 49 | 4 | GO:0042476 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte communication | 5.69e-04 | 15 | 49 | 2 | GO:0086069 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell communication | 5.69e-04 | 15 | 49 | 2 | GO:0086067 | |
| GeneOntologyBiologicalProcess | response to toxic substance | 6.01e-04 | 289 | 49 | 5 | GO:0009636 | |
| GeneOntologyBiologicalProcess | chemical homeostasis | 6.01e-04 | 1249 | 49 | 10 | GO:0048878 | |
| GeneOntologyBiologicalProcess | detection of external stimulus | 7.55e-04 | 173 | 49 | 4 | GO:0009581 | |
| GeneOntologyBiologicalProcess | detection of abiotic stimulus | 7.88e-04 | 175 | 49 | 4 | GO:0009582 | |
| GeneOntologyBiologicalProcess | regulation of metal ion transport | 1.06e-03 | 493 | 49 | 6 | GO:0010959 | |
| GeneOntologyBiologicalProcess | optic nerve development | 1.24e-03 | 22 | 49 | 2 | GO:0021554 | |
| GeneOntologyBiologicalProcess | regulation of cardiac muscle contraction | 1.24e-03 | 89 | 49 | 3 | GO:0055117 | |
| GeneOntologyBiologicalProcess | monoatomic cation homeostasis | 1.30e-03 | 705 | 49 | 7 | GO:0055080 | |
| GeneOntologyBiologicalProcess | regulation of muscle contraction | 1.34e-03 | 202 | 49 | 4 | GO:0006937 | |
| GeneOntologyBiologicalProcess | regulation of ARF protein signal transduction | 1.35e-03 | 23 | 49 | 2 | GO:0032012 | |
| GeneOntologyBiologicalProcess | monoatomic ion homeostasis | 1.44e-03 | 717 | 49 | 7 | GO:0050801 | |
| GeneOntologyBiologicalProcess | regulation of intracellular pH | 1.45e-03 | 94 | 49 | 3 | GO:0051453 | |
| GeneOntologyBiologicalProcess | ARF protein signal transduction | 1.48e-03 | 24 | 49 | 2 | GO:0032011 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus involved in sensory perception of pain | 1.73e-03 | 26 | 49 | 2 | GO:0050966 | |
| GeneOntologyBiologicalProcess | detection of temperature stimulus involved in sensory perception of pain | 1.73e-03 | 26 | 49 | 2 | GO:0050965 | |
| GeneOntologyBiologicalProcess | cardiac conduction | 1.73e-03 | 100 | 49 | 3 | GO:0061337 | |
| GeneOntologyBiologicalProcess | regulation of sodium ion transport | 1.78e-03 | 101 | 49 | 3 | GO:0002028 | |
| GeneOntologyBiologicalProcess | regulation of cellular pH | 1.78e-03 | 101 | 49 | 3 | GO:0030641 | |
| GeneOntologyBiologicalProcess | sodium ion import across plasma membrane | 1.87e-03 | 27 | 49 | 2 | GO:0098719 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | 2.02e-03 | 981 | 49 | 8 | GO:0019725 | |
| GeneOntologyBiologicalProcess | odontogenesis of dentin-containing tooth | 2.10e-03 | 107 | 49 | 3 | GO:0042475 | |
| GeneOntologyBiologicalProcess | nerve development | 2.22e-03 | 109 | 49 | 3 | GO:0021675 | |
| GeneOntologyBiologicalProcess | detection of temperature stimulus involved in sensory perception | 2.30e-03 | 30 | 49 | 2 | GO:0050961 | |
| GeneOntologyBiologicalProcess | chemosensory behavior | 2.46e-03 | 31 | 49 | 2 | GO:0007635 | |
| GeneOntologyBiologicalProcess | regulation of presynaptic membrane potential | 2.62e-03 | 32 | 49 | 2 | GO:0099505 | |
| GeneOntologyBiologicalProcess | adult locomotory behavior | 2.65e-03 | 116 | 49 | 3 | GO:0008344 | |
| GeneOntologyBiologicalProcess | detection of temperature stimulus | 2.79e-03 | 33 | 49 | 2 | GO:0016048 | |
| GeneOntologyBiologicalProcess | regulation of heart contraction | 2.87e-03 | 249 | 49 | 4 | GO:0008016 | |
| GeneOntologyBiologicalProcess | cell-cell signaling involved in cardiac conduction | 2.95e-03 | 34 | 49 | 2 | GO:0086019 | |
| GeneOntologyBiologicalProcess | regulation of monoatomic ion transmembrane transport | 3.03e-03 | 417 | 49 | 5 | GO:0034765 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic cation homeostasis | 3.12e-03 | 611 | 49 | 6 | GO:0030003 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic ion homeostasis | 3.41e-03 | 622 | 49 | 6 | GO:0006873 | |
| GeneOntologyBiologicalProcess | regulation of heart rate | 3.57e-03 | 129 | 49 | 3 | GO:0002027 | |
| GeneOntologyBiologicalProcess | sensory perception of temperature stimulus | 3.68e-03 | 38 | 49 | 2 | GO:0050951 | |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 6.39e-15 | 17 | 51 | 7 | GO:0001518 | |
| GeneOntologyCellularComponent | sodium channel complex | 5.02e-13 | 29 | 51 | 7 | GO:0034706 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 KCNH3 | 3.47e-09 | 523 | 51 | 12 | GO:1902495 |
| GeneOntologyCellularComponent | transporter complex | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 KCNH3 | 6.09e-09 | 550 | 51 | 12 | GO:1990351 |
| GeneOntologyCellularComponent | monoatomic ion channel complex | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A KCNH3 | 2.19e-08 | 378 | 51 | 10 | GO:0034702 |
| GeneOntologyCellularComponent | cation channel complex | 9.51e-08 | 235 | 51 | 8 | GO:0034703 | |
| GeneOntologyCellularComponent | axon | SLC6A2 SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ADGRL1 GRIN2A ATP1A1 OPRD1 | 1.14e-06 | 891 | 51 | 12 | GO:0030424 |
| GeneOntologyCellularComponent | presynaptic membrane | 4.68e-06 | 277 | 51 | 7 | GO:0042734 | |
| GeneOntologyCellularComponent | membrane protein complex | SCN1A SCN3A TRPC6 SCN4A SCN5A SCN8A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 PLEKHA7 KCNH3 | 4.53e-05 | 1498 | 51 | 13 | GO:0098796 |
| GeneOntologyCellularComponent | plasma membrane protein complex | 1.05e-04 | 785 | 51 | 9 | GO:0098797 | |
| GeneOntologyCellularComponent | synaptic membrane | 5.05e-04 | 583 | 51 | 7 | GO:0097060 | |
| GeneOntologyCellularComponent | intercalated disc | 6.13e-04 | 68 | 51 | 3 | GO:0014704 | |
| GeneOntologyCellularComponent | T-tubule | 9.49e-04 | 79 | 51 | 3 | GO:0030315 | |
| GeneOntologyCellularComponent | node of Ranvier | 1.08e-03 | 20 | 51 | 2 | GO:0033268 | |
| GeneOntologyCellularComponent | presynapse | 1.27e-03 | 886 | 51 | 8 | GO:0098793 | |
| GeneOntologyCellularComponent | cell-cell contact zone | 1.57e-03 | 94 | 51 | 3 | GO:0044291 | |
| GeneOntologyCellularComponent | axon initial segment | 2.27e-03 | 29 | 51 | 2 | GO:0043194 | |
| HumanPheno | Focal hemiclonic seizure | 3.11e-06 | 25 | 22 | 4 | HP:0006813 | |
| HumanPheno | Developmental regression | 5.22e-06 | 440 | 22 | 10 | HP:0002376 | |
| HumanPheno | Generalized clonic seizure | 1.11e-05 | 34 | 22 | 4 | HP:0011169 | |
| HumanPheno | Abnormal autonomic nervous system physiology | 1.31e-05 | 130 | 22 | 6 | HP:0012332 | |
| HumanPheno | Clonic seizure | 1.91e-05 | 81 | 22 | 5 | HP:0020221 | |
| HumanPheno | Focal clonic seizure | 2.62e-05 | 42 | 22 | 4 | HP:0002266 | |
| HumanPheno | Impulsivity | 2.87e-05 | 149 | 22 | 6 | HP:0100710 | |
| HumanPheno | Complex febrile seizure | 3.78e-05 | 16 | 22 | 3 | HP:0011172 | |
| HumanPheno | Abnormality of the autonomic nervous system | 5.75e-05 | 346 | 22 | 8 | HP:0002270 | |
| HumanPheno | Non-convulsive status epilepticus without coma | 7.60e-05 | 20 | 22 | 3 | HP:0032671 | |
| HumanPheno | Dysesthesia | 8.84e-05 | 21 | 22 | 3 | HP:0012534 | |
| HumanPheno | Abnormality of the peripheral nervous system | 1.05e-04 | 617 | 22 | 10 | HP:0410008 | |
| HumanPheno | Generalized tonic seizure | 1.40e-04 | 64 | 22 | 4 | HP:0010818 | |
| HumanPheno | Intellectual disability, borderline | 1.51e-04 | 25 | 22 | 3 | HP:0006889 | |
| HumanPheno | Focal impaired awareness seizure | 1.61e-04 | 126 | 22 | 5 | HP:0002384 | |
| HumanPheno | Allodynia | 1.77e-04 | 5 | 22 | 2 | HP:0012533 | |
| HumanPheno | Status epilepticus | 1.81e-04 | 207 | 22 | 6 | HP:0002133 | |
| HumanPheno | Status epilepticus without prominent motor symptoms | 1.91e-04 | 27 | 22 | 3 | HP:0031475 | |
| HumanPheno | Simple febrile seizure | 1.91e-04 | 27 | 22 | 3 | HP:0011171 | |
| HumanPheno | Focal aware seizure | 2.14e-04 | 28 | 22 | 3 | HP:0002349 | |
| HumanPheno | Episodic hypokalemia | 2.64e-04 | 6 | 22 | 2 | HP:0012726 | |
| HumanPheno | Paresthesia | 3.01e-04 | 144 | 22 | 5 | HP:0003401 | |
| HumanPheno | Infection-related seizure | 3.11e-04 | 145 | 22 | 5 | HP:0032892 | |
| HumanPheno | Seizure precipitated by febrile infection | 3.11e-04 | 145 | 22 | 5 | HP:0032894 | |
| HumanPheno | Febrile seizure (within the age range of 3 months to 6 years) | 3.11e-04 | 145 | 22 | 5 | HP:0002373 | |
| HumanPheno | Hypokalemia | 3.17e-04 | 79 | 22 | 4 | HP:0002900 | |
| HumanPheno | Abnormal peripheral nervous system morphology | WFS1 SCN1A SCN3A SCN4A SCN8A SCN9A SCN10A PEX2 TCIRG1 GRIN2A ATP1A1 TTPA DEGS1 EDNRB | 3.97e-04 | 1395 | 22 | 14 | HP:0000759 |
| HumanPheno | Peripheral neuropathy | WFS1 SCN1A SCN4A SCN9A SCN10A GRIN2A ATP1A1 TTPA DEGS1 EDNRB | 4.09e-04 | 725 | 22 | 10 | HP:0009830 |
| HumanPheno | EEG with spike-wave complexes | 4.80e-04 | 88 | 22 | 4 | HP:0010850 | |
| HumanPheno | EEG with abnormally slow frequencies | 4.80e-04 | 88 | 22 | 4 | HP:0011203 | |
| HumanPheno | Photosensitive myoclonic seizure | 4.91e-04 | 8 | 22 | 2 | HP:0001327 | |
| HumanPheno | Cyanotic episode | 4.91e-04 | 8 | 22 | 2 | HP:0200048 | |
| HumanPheno | Reduced tendon reflexes | 6.10e-04 | 617 | 22 | 9 | HP:0001315 | |
| HumanPheno | Abnormal nervous system electrophysiology | SCN1A SCN3A SCN4A SCN8A SCN9A PEX2 TCIRG1 GRIN2A TTPA DEGS1 EDNRB | 6.59e-04 | 924 | 22 | 11 | HP:0001311 |
| HumanPheno | Apnea | 6.82e-04 | 372 | 22 | 7 | HP:0002104 | |
| HumanPheno | Bradycardia | 7.22e-04 | 98 | 22 | 4 | HP:0001662 | |
| HumanPheno | Apneic episodes in infancy | 7.85e-04 | 10 | 22 | 2 | HP:0005949 | |
| HumanPheno | Sudden unexpected death in epilepsy | 7.85e-04 | 10 | 22 | 2 | HP:0033258 | |
| HumanPheno | Erythromelalgia | 7.85e-04 | 10 | 22 | 2 | HP:0032147 | |
| HumanPheno | Gastrostomy tube feeding in infancy | 9.04e-04 | 104 | 22 | 4 | HP:0011471 | |
| HumanPheno | Atypical absence seizure | 9.41e-04 | 46 | 22 | 3 | HP:0007270 | |
| HumanPheno | Limited neck range of motion | 9.57e-04 | 11 | 22 | 2 | HP:0000466 | |
| HumanPheno | Facial paralysis | 9.57e-04 | 11 | 22 | 2 | HP:0007209 | |
| HumanPheno | EEG with focal sharp waves | 1.14e-03 | 12 | 22 | 2 | HP:0011196 | |
| HumanPheno | Epilepsia partialis continua | 1.14e-03 | 12 | 22 | 2 | HP:0012847 | |
| HumanPheno | Focal automatism seizure | 1.14e-03 | 12 | 22 | 2 | HP:0032898 | |
| HumanPheno | Abnormal blood potassium concentration | 1.23e-03 | 113 | 22 | 4 | HP:0011042 | |
| HumanPheno | Abnormality of pain sensation | 1.23e-03 | 113 | 22 | 4 | HP:0010832 | |
| HumanPheno | Bilateral tonic-clonic seizure with focal onset | 1.35e-03 | 52 | 22 | 3 | HP:0007334 | |
| HumanPheno | Bilateral tonic-clonic seizure with generalized onset | 1.35e-03 | 52 | 22 | 3 | HP:0025190 | |
| HumanPheno | EEG with multifocal slow activity | 1.35e-03 | 52 | 22 | 3 | HP:0010844 | |
| HumanPheno | Generalized cerebral atrophy/hypoplasia | 1.35e-03 | 13 | 22 | 2 | HP:0007058 | |
| HumanPheno | EEG with irregular generalized spike and wave complexes | 1.35e-03 | 13 | 22 | 2 | HP:0001326 | |
| MousePheno | abnormal stationary movement | 1.54e-06 | 147 | 35 | 6 | MP:0001388 | |
| MousePheno | seizures | 2.29e-06 | 360 | 35 | 8 | MP:0002064 | |
| MousePheno | abnormal touch/ nociception | 3.17e-06 | 376 | 35 | 8 | MP:0001968 | |
| MousePheno | abnormal pain threshold | 3.65e-06 | 267 | 35 | 7 | MP:0001970 | |
| MousePheno | abnormal head movements | 5.36e-06 | 103 | 35 | 5 | MP:0000436 | |
| MousePheno | abnormal breathing pattern | 8.38e-06 | 303 | 35 | 7 | MP:0001951 | |
| MousePheno | abnormal seizure response to inducing agent | 9.40e-06 | 201 | 35 | 6 | MP:0009357 | |
| MousePheno | abnormal behavioral response to xenobiotic | 9.52e-06 | 309 | 35 | 7 | MP:0009745 | |
| MousePheno | abnormal action potential | 1.87e-05 | 133 | 35 | 5 | MP:0005402 | |
| MousePheno | abnormal spike wave discharge | 2.81e-05 | 24 | 35 | 3 | MP:0008840 | |
| MousePheno | abnormal sensory capabilities/reflexes/nociception | SLC6A2 VOPP1 WFS1 SCN1A TRPC6 SCN4A SCN8A SCN9A SCN10A PEX2 GRIN2A EDNRB OPRD1 | 3.27e-05 | 1486 | 35 | 13 | MP:0002067 |
| MousePheno | abnormal respiratory function | 4.93e-05 | 399 | 35 | 7 | MP:0002327 | |
| MousePheno | abnormal chemically-elicited antinociception | 5.02e-05 | 29 | 35 | 3 | MP:0001980 | |
| MousePheno | abnormal thermal nociception | 5.73e-05 | 168 | 35 | 5 | MP:0002733 | |
| MousePheno | hypoalgesia | 6.06e-05 | 170 | 35 | 5 | MP:0003043 | |
| MousePheno | abnormal seizure response to electrical stimulation | 6.79e-05 | 32 | 35 | 3 | MP:0001650 | |
| MousePheno | abnormal single cell response | 8.91e-05 | 35 | 35 | 3 | MP:0003463 | |
| MousePheno | absence seizures | 8.91e-05 | 35 | 35 | 3 | MP:0003216 | |
| MousePheno | increased anxiety-related response | 1.09e-04 | 311 | 35 | 6 | MP:0001363 | |
| MousePheno | abnormal behavioral response to addictive substance | 1.18e-04 | 102 | 35 | 4 | MP:0009748 | |
| MousePheno | ventricular fibrillation | 1.27e-04 | 7 | 35 | 2 | MP:0006110 | |
| MousePheno | nonconvulsive seizures | 1.33e-04 | 40 | 35 | 3 | MP:0000948 | |
| MousePheno | abnormal nervous system electrophysiology | 1.48e-04 | 329 | 35 | 6 | MP:0002272 | |
| MousePheno | stereotypic behavior | 1.79e-04 | 214 | 35 | 5 | MP:0001408 | |
| MousePheno | impaired ability to fire action potentials | 4.67e-04 | 13 | 35 | 2 | MP:0002578 | |
| MousePheno | abnormal seizure response to pharmacological agent | 4.77e-04 | 147 | 35 | 4 | MP:0000950 | |
| MousePheno | abnormal kindling response | 5.44e-04 | 14 | 35 | 2 | MP:0001499 | |
| MousePheno | fibrillation | 5.44e-04 | 14 | 35 | 2 | MP:0006109 | |
| MousePheno | sinus bradycardia | 5.44e-04 | 14 | 35 | 2 | MP:0010637 | |
| MousePheno | abnormal depression-related behavior | 5.97e-04 | 156 | 35 | 4 | MP:0003360 | |
| MousePheno | abnormal respiration | 5.98e-04 | 598 | 35 | 7 | MP:0001943 | |
| MousePheno | enhanced behavioral response to xenobiotic | 6.73e-04 | 69 | 35 | 3 | MP:0009746 | |
| MousePheno | abnormal motor coordination/balance | 1.16e-03 | 873 | 35 | 8 | MP:0001516 | |
| MousePheno | postnatal growth retardation | 1.23e-03 | 881 | 35 | 8 | MP:0001732 | |
| MousePheno | akinesia | 1.24e-03 | 21 | 35 | 2 | MP:0002690 | |
| MousePheno | abnormal postnatal growth | 1.49e-03 | 907 | 35 | 8 | MP:0001731 | |
| MousePheno | dystonia | 1.49e-03 | 23 | 35 | 2 | MP:0005323 | |
| Domain | Na_channel_asu | 8.79e-17 | 10 | 51 | 7 | IPR001696 | |
| Domain | Na_trans_assoc | 8.79e-17 | 10 | 51 | 7 | IPR010526 | |
| Domain | Na_trans_assoc | 8.79e-17 | 10 | 51 | 7 | PF06512 | |
| Domain | Na_trans_cytopl | 7.43e-13 | 6 | 51 | 5 | PF11933 | |
| Domain | Na_trans_cytopl | 7.43e-13 | 6 | 51 | 5 | IPR024583 | |
| Domain | Ion_trans_dom | 2.09e-11 | 114 | 51 | 9 | IPR005821 | |
| Domain | Ion_trans | 2.09e-11 | 114 | 51 | 9 | PF00520 | |
| Domain | Channel_four-helix_dom | 1.76e-10 | 57 | 51 | 7 | IPR027359 | |
| Domain | - | 1.76e-10 | 57 | 51 | 7 | 1.20.120.350 | |
| Domain | IQ_motif_EF-hand-BS | 4.64e-09 | 90 | 51 | 7 | IPR000048 | |
| Domain | IQ | 5.84e-09 | 93 | 51 | 7 | PS50096 | |
| Domain | IQ | 3.83e-08 | 71 | 51 | 6 | PF00612 | |
| Domain | IQ | 8.50e-08 | 81 | 51 | 6 | SM00015 | |
| Domain | SSD | 5.59e-04 | 13 | 51 | 2 | PS50156 | |
| Domain | SSD | 5.59e-04 | 13 | 51 | 2 | IPR000731 | |
| Domain | TAS2R | 2.28e-03 | 26 | 51 | 2 | PF05296 | |
| Domain | T2R | 2.28e-03 | 26 | 51 | 2 | IPR007960 | |
| Domain | EF-hand-dom_pair | 7.74e-03 | 287 | 51 | 4 | IPR011992 | |
| Domain | GPCR_2-like | 1.17e-02 | 60 | 51 | 2 | IPR017981 | |
| Domain | GPCR_2_secretin-like | 1.17e-02 | 60 | 51 | 2 | IPR000832 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 4.35e-12 | 31 | 44 | 7 | M877 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 5.56e-12 | 32 | 44 | 7 | M27455 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 5.65e-09 | 130 | 44 | 8 | M27454 | |
| Pathway | REACTOME_L1CAM_INTERACTIONS | 8.49e-08 | 121 | 44 | 7 | M872 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 1.83e-07 | 203 | 44 | 8 | M5485 | |
| Pathway | WP_ADHD_AND_AUTISM_ASD_PATHWAYS | 1.58e-06 | 367 | 44 | 9 | M48346 | |
| Pathway | WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION | 1.22e-05 | 46 | 44 | 4 | M46450 | |
| Pathway | REACTOME_NERVOUS_SYSTEM_DEVELOPMENT | 5.79e-05 | 575 | 44 | 9 | M29853 | |
| Pathway | WP_DRAVET_SYNDROME | 8.80e-05 | 28 | 44 | 3 | M45519 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 4.18e-04 | 47 | 44 | 3 | M42524 | |
| Pathway | WP_RETT_SYNDROME | 4.45e-04 | 48 | 44 | 3 | M39759 | |
| Pathway | WP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL | 1.52e-03 | 73 | 44 | 3 | MM16641 | |
| Pubmed | 3.41e-19 | 9 | 51 | 7 | 16382098 | ||
| Pubmed | 1.25e-14 | 13 | 51 | 6 | 15123669 | ||
| Pubmed | A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. | 3.32e-14 | 6 | 51 | 5 | 23652591 | |
| Pubmed | 6.95e-13 | 9 | 51 | 5 | 15746173 | ||
| Pubmed | Early development of electrical excitability in the mouse enteric nervous system. | 2.05e-11 | 5 | 51 | 4 | 22875929 | |
| Pubmed | 2.05e-11 | 5 | 51 | 4 | 17724025 | ||
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | 2.93e-11 | 139 | 51 | 8 | 16985003 | |
| Pubmed | Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. | 2.01e-09 | 12 | 51 | 4 | 30175250 | |
| Pubmed | 2.97e-09 | 3 | 51 | 3 | 33895391 | ||
| Pubmed | 2.97e-09 | 3 | 51 | 3 | 19699781 | ||
| Pubmed | 2.97e-09 | 3 | 51 | 3 | 20038812 | ||
| Pubmed | 1.19e-08 | 4 | 51 | 3 | 17537961 | ||
| Pubmed | 1.19e-08 | 4 | 51 | 3 | 35031483 | ||
| Pubmed | 1.19e-08 | 4 | 51 | 3 | 29578003 | ||
| Pubmed | 1.19e-08 | 4 | 51 | 3 | 22260870 | ||
| Pubmed | 2.96e-08 | 5 | 51 | 3 | 8812438 | ||
| Pubmed | 5.92e-08 | 6 | 51 | 3 | 16029194 | ||
| Pubmed | 5.92e-08 | 6 | 51 | 3 | 23711479 | ||
| Pubmed | 1.04e-07 | 7 | 51 | 3 | 15272007 | ||
| Pubmed | Pain without nociceptors? Nav1.7-independent pain mechanisms. | 1.04e-07 | 7 | 51 | 3 | 24440715 | |
| Pubmed | 1.65e-07 | 8 | 51 | 3 | 25101983 | ||
| Pubmed | 1.65e-07 | 8 | 51 | 3 | 9412493 | ||
| Pubmed | Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse. | 2.48e-07 | 9 | 51 | 3 | 8854872 | |
| Pubmed | Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. | 2.48e-07 | 9 | 51 | 3 | 17884088 | |
| Pubmed | A common genetic variant within SCN10A modulates cardiac SCN5A expression. | 2.11e-06 | 2 | 51 | 2 | 24642470 | |
| Pubmed | Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy. | 2.11e-06 | 2 | 51 | 2 | 37901435 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 18079277 | ||
| Pubmed | An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior. | 2.11e-06 | 2 | 51 | 2 | 26410685 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 26861708 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 15047701 | ||
| Pubmed | Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8. | 2.11e-06 | 2 | 51 | 2 | 16111501 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 10619433 | ||
| Pubmed | Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A. | 2.11e-06 | 2 | 51 | 2 | 24990319 | |
| Pubmed | Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif. | 2.11e-06 | 2 | 51 | 2 | 30944319 | |
| Pubmed | Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression. | 2.11e-06 | 2 | 51 | 2 | 25172946 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 16025302 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 31292628 | ||
| Pubmed | Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. | 2.11e-06 | 2 | 51 | 2 | 16054936 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 32116538 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 33712547 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 33411788 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 31943325 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 11834499 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 21295407 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 27690330 | ||
| Pubmed | Sodium channel slow inactivation interferes with open channel block. | 2.11e-06 | 2 | 51 | 2 | 27174182 | |
| Pubmed | Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome. | 2.11e-06 | 2 | 51 | 2 | 24998131 | |
| Pubmed | Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome. | 2.11e-06 | 2 | 51 | 2 | 23965409 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 24360055 | ||
| Pubmed | Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics. | 2.11e-06 | 2 | 51 | 2 | 37665666 | |
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 17881658 | ||
| Pubmed | 2.11e-06 | 2 | 51 | 2 | 32330377 | ||
| Pubmed | 5.15e-06 | 23 | 51 | 3 | 16637659 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 19284629 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 12610651 | ||
| Pubmed | The cell and molecular basis of mechanical, cold, and inflammatory pain. | 6.32e-06 | 3 | 51 | 2 | 18669863 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 23859570 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 22449024 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 18784617 | ||
| Pubmed | Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury. | 6.32e-06 | 3 | 51 | 2 | 22875917 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 17544618 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 32845893 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 28518218 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 28074005 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 27816501 | ||
| Pubmed | Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance. | 6.32e-06 | 3 | 51 | 2 | 24704313 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 38999942 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 15314237 | ||
| Pubmed | The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels. | 6.32e-06 | 3 | 51 | 2 | 28117367 | |
| Pubmed | Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin. | 6.32e-06 | 3 | 51 | 2 | 15746172 | |
| Pubmed | Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain. | 6.32e-06 | 3 | 51 | 2 | 29497094 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 17928448 | ||
| Pubmed | Yield of peripheral sodium channels gene screening in pure small fibre neuropathy. | 6.32e-06 | 3 | 51 | 2 | 30554136 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 14973256 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 34991641 | ||
| Pubmed | Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. | 6.32e-06 | 3 | 51 | 2 | 17052333 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 16258256 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 26182346 | ||
| Pubmed | De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy. | 6.32e-06 | 3 | 51 | 2 | 31054517 | |
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 25998140 | ||
| Pubmed | 6.32e-06 | 3 | 51 | 2 | 15302875 | ||
| Pubmed | 9.48e-06 | 28 | 51 | 3 | 19352218 | ||
| Pubmed | Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis. | 1.26e-05 | 4 | 51 | 2 | 38172636 | |
| Pubmed | 1.26e-05 | 4 | 51 | 2 | 20004937 | ||
| Pubmed | 1.26e-05 | 4 | 51 | 2 | 10198179 | ||
| Pubmed | 1.26e-05 | 4 | 51 | 2 | 21156207 | ||
| Pubmed | Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes. | 1.26e-05 | 4 | 51 | 2 | 39163201 | |
| Pubmed | Genome-wide association studies of the PR interval in African Americans. | 1.26e-05 | 4 | 51 | 2 | 21347284 | |
| Pubmed | Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli. | 1.26e-05 | 4 | 51 | 2 | 27604420 | |
| Pubmed | 1.26e-05 | 4 | 51 | 2 | 23632330 | ||
| Pubmed | Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. | 1.26e-05 | 4 | 51 | 2 | 22531176 | |
| Pubmed | Models for discovery of targeted therapy in genetic epileptic encephalopathies. | 1.26e-05 | 4 | 51 | 2 | 28742937 | |
| Pubmed | 1.26e-05 | 4 | 51 | 2 | 35801810 | ||
| Pubmed | Use of recombinant inbred strains for studying genetic determinants of responses to alcohol. | 1.26e-05 | 4 | 51 | 2 | 8974318 | |
| Pubmed | 2.10e-05 | 5 | 51 | 2 | 1679748 | ||
| Pubmed | Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer. | 2.10e-05 | 5 | 51 | 2 | 22706305 | |
| Pubmed | Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. | 2.10e-05 | 5 | 51 | 2 | 23463857 | |
| Pubmed | 2.10e-05 | 5 | 51 | 2 | 19193724 | ||
| Pubmed | 2.10e-05 | 5 | 51 | 2 | 23872634 | ||
| Pubmed | Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. | 2.10e-05 | 5 | 51 | 2 | 15548568 | |
| Interaction | SCN11A interactions | 1.63e-10 | 15 | 47 | 5 | int:SCN11A | |
| Interaction | CACNA1D interactions | 2.28e-09 | 24 | 47 | 5 | int:CACNA1D | |
| Interaction | SCN5A interactions | 7.90e-08 | 47 | 47 | 5 | int:SCN5A | |
| Interaction | SCN8A interactions | 1.22e-07 | 20 | 47 | 4 | int:SCN8A | |
| Interaction | SCN1A interactions | 5.91e-07 | 29 | 47 | 4 | int:SCN1A | |
| Interaction | SCN10A interactions | 1.94e-06 | 11 | 47 | 3 | int:SCN10A | |
| Interaction | TAP2 interactions | 2.61e-06 | 94 | 47 | 5 | int:TAP2 | |
| Interaction | NALCN interactions | 4.25e-06 | 14 | 47 | 3 | int:NALCN | |
| Interaction | CACNA1A interactions | 9.75e-06 | 123 | 47 | 5 | int:CACNA1A | |
| Interaction | SCN9A interactions | 1.54e-05 | 21 | 47 | 3 | int:SCN9A | |
| Interaction | NEDD4 interactions | 3.33e-05 | 544 | 47 | 8 | int:NEDD4 | |
| Interaction | TSPAN15 interactions | 4.19e-05 | 276 | 47 | 6 | int:TSPAN15 | |
| Interaction | SCN4A interactions | 7.99e-05 | 98 | 47 | 4 | int:SCN4A | |
| Interaction | CACNA1B interactions | 8.74e-05 | 37 | 47 | 3 | int:CACNA1B | |
| Interaction | NEDD4L interactions | 9.49e-05 | 320 | 47 | 6 | int:NEDD4L | |
| Interaction | FGF14 interactions | 1.28e-04 | 42 | 47 | 3 | int:FGF14 | |
| Interaction | PEX12 interactions | 1.47e-04 | 44 | 47 | 3 | int:PEX12 | |
| Interaction | SCN4B interactions | 1.48e-04 | 8 | 47 | 2 | int:SCN4B | |
| Interaction | DLG3 interactions | 2.45e-04 | 131 | 47 | 4 | int:DLG3 | |
| Interaction | CACNA1C interactions | 3.89e-04 | 61 | 47 | 3 | int:CACNA1C | |
| Cytoband | 2q24 | 6.61e-05 | 11 | 51 | 2 | 2q24 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q24 | 3.91e-04 | 127 | 51 | 3 | chr2q24 | |
| Cytoband | 12q13 | 2.86e-03 | 71 | 51 | 2 | 12q13 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 3.62e-18 | 9 | 38 | 7 | 1203 | |
| GeneFamily | Olfactory receptors, family 11 | 1.06e-03 | 23 | 38 | 2 | 159 | |
| GeneFamily | Taste 2 receptors | 3.03e-03 | 39 | 38 | 2 | 1162 | |
| ToppCell | Endothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id | 2.98e-06 | 196 | 51 | 5 | 36f95f9ef74eb951e41ef46fd136ceaef45208fc | |
| ToppCell | Tracheal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 3.21e-06 | 199 | 51 | 5 | cefc3b50f65e95da850e4720c7b44bf584073491 | |
| ToppCell | Tracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 3.21e-06 | 199 | 51 | 5 | aaa460c389cd6d38a13ba1a446f91a94f9573ad8 | |
| ToppCell | facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.30e-05 | 145 | 51 | 4 | 96712c68ab759d7ade0d912581a1a7c25dc6def8 | |
| ToppCell | PND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass | 2.63e-05 | 150 | 51 | 4 | 5b111ec11a642d63fafa7e1422e36f81a2776531 | |
| ToppCell | PND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass | 2.63e-05 | 150 | 51 | 4 | 2d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 3.81e-05 | 165 | 51 | 4 | 347b59aa625a8a960828b8620824d8ac48990e07 | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 3.81e-05 | 165 | 51 | 4 | 1890f9c33b0c5b381d57f97042da2610a093a6de | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 3.81e-05 | 165 | 51 | 4 | 507c89ece0a336b8e9c65b79889a714e17ddca27 | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 3.81e-05 | 165 | 51 | 4 | 39a25be081a5d59c7cf107a997d352793d5025fb | |
| ToppCell | facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.90e-05 | 176 | 51 | 4 | 74f851a398c7562dd713bc0d8d488c0037243112 | |
| ToppCell | facs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.90e-05 | 176 | 51 | 4 | 31b5459a978d5cdde0af03a77401e0464d8c95ba | |
| ToppCell | 3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 5.46e-05 | 181 | 51 | 4 | e898ecb8d8f2eb2204225b7b0d665cadcd241139 | |
| ToppCell | 367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells) | 5.46e-05 | 181 | 51 | 4 | b244ecaa442bbef51289d8ec574ef08fa9e96318 | |
| ToppCell | 367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells) | 5.46e-05 | 181 | 51 | 4 | dd79de8098edb385a0f85d0e9621503cdf76ec43 | |
| ToppCell | 5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 5.58e-05 | 182 | 51 | 4 | 53c267ee327e116dbd89d5927ed3bdf78d25ee62 | |
| ToppCell | PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung | 5.95e-05 | 185 | 51 | 4 | a8946379fc066903fe8f4bc9cbf693b7b424a0cd | |
| ToppCell | 5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 6.07e-05 | 186 | 51 | 4 | 40070d9cd20188ba49b32acfca9bc16256b38bf5 | |
| ToppCell | 3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 6.07e-05 | 186 | 51 | 4 | 20340a5b5cc7f07386498a4ef937d6fbc9e347c4 | |
| ToppCell | facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.46e-05 | 189 | 51 | 4 | b98f60875b1a12b2ec9dc91889298ae57f98602f | |
| ToppCell | COVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type | 6.46e-05 | 189 | 51 | 4 | c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3 | |
| ToppCell | facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.46e-05 | 189 | 51 | 4 | e758b264c0a47127e33e66c395cf5a3224c7305b | |
| ToppCell | 3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.59e-05 | 190 | 51 | 4 | bdbfaced785db79ff965f332759be258dbf743cf | |
| ToppCell | Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 6.73e-05 | 191 | 51 | 4 | 06760c3bb40e4f66879a5f5e09c9abfce4ebbba3 | |
| ToppCell | COVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type | 6.87e-05 | 192 | 51 | 4 | cbe57cda44232b183821ac633b60a2668265e616 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.01e-05 | 193 | 51 | 4 | be28070c049e7cb68bcd54f582226eb2f5e4bc1c | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.01e-05 | 193 | 51 | 4 | 0c652ebe22ce5d2927599dd97ef1920547858395 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.01e-05 | 193 | 51 | 4 | 8689a70a33a7c3823dc647d41ac0160e7c3ae396 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.01e-05 | 193 | 51 | 4 | 461919ab422bc9d1fcff7a3a4757c75239041d7e | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.01e-05 | 193 | 51 | 4 | 0dd810ad900d3e586551622b2c1de39d76fd6a7f | |
| ToppCell | 5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 7.01e-05 | 193 | 51 | 4 | d5930f7bd9b299f792212d40a3272a37adf64a82 | |
| ToppCell | 3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 7.01e-05 | 193 | 51 | 4 | 8851275bcf4ecd6e87a91c8784fc5d76d246ff3b | |
| ToppCell | 3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 7.01e-05 | 193 | 51 | 4 | 040f6bb42aa41d0921371fdda1cc0912c4fe1930 | |
| ToppCell | 3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 7.01e-05 | 193 | 51 | 4 | e468287c8b30c56d1de65e8347ade233ba6cf584 | |
| ToppCell | Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32 | 7.12e-05 | 70 | 51 | 3 | be300c0447735aba89df4c3082b81eb5abf22770 | |
| ToppCell | Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32 | 7.12e-05 | 70 | 51 | 3 | 2121ba6a0beb2a8fdc589ff1063e7d8c2c3c68f6 | |
| ToppCell | Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32 | 7.12e-05 | 70 | 51 | 3 | cd6bca68fe52f451716fc8c0b1745984bc9ec057 | |
| ToppCell | (08)_PNEC|World / shred by cell type and Timepoint | 7.44e-05 | 196 | 51 | 4 | 2ee37155c03cd5009427a4bffe6c80ed2ac6939e | |
| ToppCell | Striatum-Neuronal-Excitatory|Striatum / BrainAtlas - Mouse McCarroll V32 | 7.44e-05 | 196 | 51 | 4 | 67400193ba469cf4d939e94f5ed94995e384bc07 | |
| ToppCell | Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype | 7.58e-05 | 197 | 51 | 4 | 15b87fd3906d7388c271d30d0c64b1bcc490801c | |
| ToppCell | Transverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass | 7.58e-05 | 197 | 51 | 4 | a58af0ea82f76f2a7abac1f62629ff20d552fc63 | |
| ToppCell | Somatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 7.73e-05 | 198 | 51 | 4 | c01091ef18e096d792ea2a7a715764a5b215355f | |
| ToppCell | 5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 7.73e-05 | 198 | 51 | 4 | 50504a3871f76d6a5b439a56450d7770f4501eb0 | |
| ToppCell | primary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 7.73e-05 | 198 | 51 | 4 | 6d18b45eda4014759e6dd282d78ffd28df8a6044 | |
| ToppCell | mLN-B_cell-B_cell_memory|B_cell / Region, Cell class and subclass | 7.73e-05 | 198 | 51 | 4 | e2c63ca9f82f8524447e398b11a676b22d2f58ce | |
| ToppCell | Primary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 7.73e-05 | 198 | 51 | 4 | 4ca5ff320905ab4ff60ed90a5522227c782142a6 | |
| ToppCell | Parenchyma_COVID-19-Endothelial-TX-Lymphatic|Parenchyma_COVID-19 / Sample group, Lineage and Cell type | 7.89e-05 | 199 | 51 | 4 | 88f33b8dcd837abfa1d12c28719e073a7da6e979 | |
| ToppCell | Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 7.89e-05 | 199 | 51 | 4 | 64b19aff72e2a109cb5857cb248bd4712dd49b43 | |
| ToppCell | Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 7.89e-05 | 199 | 51 | 4 | 2b9e1e069b36b3a61cc3e384f4523687b0e03905 | |
| ToppCell | Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 7.89e-05 | 199 | 51 | 4 | 1587d24b19f5bb64a3b6cc1df87c7c472cf41672 | |
| ToppCell | Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 7.89e-05 | 199 | 51 | 4 | a9c2041e54899cb8ccc026758647f3ae3ca457dd | |
| ToppCell | Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-GGH-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic | 8.04e-05 | 200 | 51 | 4 | 48303e499251d6754cfa991dc2d96c5563b2123c | |
| ToppCell | Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 8.04e-05 | 200 | 51 | 4 | f99d0d3f51b4893fa7898c5b435494358a654cbd | |
| ToppCell | Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09) | 8.04e-05 | 200 | 51 | 4 | e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1 | |
| ToppCell | Parenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type | 8.04e-05 | 200 | 51 | 4 | 4ec8e30dd241d83a1bba1c5967b6a4656afbfafd | |
| ToppCell | Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-GGH|Neuronal / cells hierarchy compared to all cells using T-Statistic | 8.04e-05 | 200 | 51 | 4 | 4802dd6cae84b41746227a5d1aa1c9b858495e36 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 4.64e-04 | 132 | 51 | 3 | 97e7d5f7086c6213aec4eaa581bc182338189029 | |
| ToppCell | Substantia_nigra-Macroglia-ASTROCYTE|Substantia_nigra / BrainAtlas - Mouse McCarroll V32 | 4.85e-04 | 134 | 51 | 3 | a632d78890fcc20db81d2cf6b299470706d2e182 | |
| ToppCell | Substantia_nigra-Macroglia-ASTROCYTE-Gja1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32 | 4.85e-04 | 134 | 51 | 3 | 8be2db71d9d29f9a57a64efdc89cf8c3e32b363b | |
| ToppCell | facs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.17e-04 | 137 | 51 | 3 | 4dcb15de821439011df1bb0bbd7682d674bd725d | |
| ToppCell | facs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.17e-04 | 137 | 51 | 3 | c05ceeb7b483324604cb3f647d2da2b3786071b1 | |
| ToppCell | normal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass | 7.26e-04 | 154 | 51 | 3 | afdc385397c7b13c9348eeef95f109f2363057ae | |
| ToppCell | facs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.68e-04 | 157 | 51 | 3 | 9021900d9b1a71210c9c414a9d165eaf399eb607 | |
| ToppCell | facs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.68e-04 | 157 | 51 | 3 | c8c627ca181856cd31dba4cf073c2be659a49dc1 | |
| ToppCell | Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type. | 7.82e-04 | 158 | 51 | 3 | 1f94622186d8329357fa06785e03eeacf29ab1ce | |
| ToppCell | facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.82e-04 | 158 | 51 | 3 | f296ca24fdedc33f1d24b79e7660763114ce7fa3 | |
| ToppCell | facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.82e-04 | 158 | 51 | 3 | 8c7108f2c40d97a317762ba0b8eca76542b2ebaf | |
| ToppCell | TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9 | 7.96e-04 | 159 | 51 | 3 | fb222c42f66901852b01cec073ec0732245ee973 | |
| ToppCell | TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7|TCGA-Liver / Sample_Type by Project: Shred V9 | 7.96e-04 | 159 | 51 | 3 | 70288df54adab167c0f50675128619299077db11 | |
| ToppCell | facs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.11e-04 | 160 | 51 | 3 | 55f599df6e3b7a5a505df4b094c834281311d94a | |
| ToppCell | facs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.11e-04 | 160 | 51 | 3 | 296e53e1e0786346d38db2d4188b9a1c0430627b | |
| ToppCell | TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9 | 8.26e-04 | 161 | 51 | 3 | 52239a887799362256ecd7e740b716b88ed59a62 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 8.26e-04 | 161 | 51 | 3 | 133b4fadb499e842c19f573f9cf09ce08c1d4813 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 8.26e-04 | 161 | 51 | 3 | cb177ca10d848d0e25399ab5ebfcde1071fb94c2 | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.26e-04 | 161 | 51 | 3 | 9f02b94e29e60d50e92eaa748ebf0c36d3671bb3 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 8.26e-04 | 161 | 51 | 3 | 9466b8658244116f8d21f2f88fb8c2d184b1bdf2 | |
| ToppCell | Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32 | 8.26e-04 | 161 | 51 | 3 | ebcd5066e82b7760b9da6adc02d11258d1309dab | |
| ToppCell | facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 8.41e-04 | 162 | 51 | 3 | bf886e22ff2a20353499004b53f25fb9e6574896 | |
| ToppCell | Children_(3_yrs)-Immune-dendritic_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor | 8.41e-04 | 162 | 51 | 3 | 86a0b9dabd150dc993bfc0f3344804de7f8e4042 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 8.41e-04 | 162 | 51 | 3 | 96c6e94a10b124a1d25dcd705ec5aaa8609c1089 | |
| ToppCell | 3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 8.71e-04 | 164 | 51 | 3 | 57301178e420983c0cb72178e288a3a0449fdda3 | |
| ToppCell | facs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.71e-04 | 164 | 51 | 3 | 1d0d88132baaa3154c3e6e4ef0aff795afab08a2 | |
| ToppCell | facs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.71e-04 | 164 | 51 | 3 | bd2e10b015d5e6a338675500ec5d81dc39583b3e | |
| ToppCell | 356C-Myeloid-Monocyte-CD16+_Monocyte|356C / Donor, Lineage, Cell class and subclass (all cells) | 8.86e-04 | 165 | 51 | 3 | 35a6de30438de364ccca948fc932da541a69ef89 | |
| ToppCell | PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 9.02e-04 | 166 | 51 | 3 | bb8135119dc37fdbba476599a56d368f422688dc | |
| ToppCell | PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung | 9.18e-04 | 167 | 51 | 3 | 49b19159c62d33d65ed1e59a148c11ae902fd41c | |
| ToppCell | 356C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells) | 9.18e-04 | 167 | 51 | 3 | 7e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07 | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.18e-04 | 167 | 51 | 3 | 3dfec2fcc36caa6e394efae5e540a6fa28759977 | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.18e-04 | 167 | 51 | 3 | 95b3b5ba3414729f0460a26a0deca48de0cbe33e | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.18e-04 | 167 | 51 | 3 | 9480739587d51e67a281778b9bddd7b5ffc3ad92 | |
| ToppCell | facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.34e-04 | 168 | 51 | 3 | 06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46 | |
| ToppCell | 368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|368C / Donor, Lineage, Cell class and subclass (all cells) | 9.34e-04 | 168 | 51 | 3 | dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6 | |
| ToppCell | Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32 | 9.34e-04 | 168 | 51 | 3 | 6db453cbbbaf4144a86fadcfa5805d33396713b5 | |
| ToppCell | NS-critical-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined) | 9.34e-04 | 168 | 51 | 3 | 6a233045638cb83dab64789b996b7598c325001e | |
| ToppCell | 368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells) | 9.34e-04 | 168 | 51 | 3 | a74c8a9e3299183fba31ce3053ef325b5dbcd104 | |
| ToppCell | facs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.34e-04 | 168 | 51 | 3 | 1002f058a340763e3d8de0bd1f0547a903526ec6 | |
| ToppCell | 10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 9.50e-04 | 169 | 51 | 3 | 2833a8a7094e4d407eb923f2bc59b9b112c6bae4 | |
| ToppCell | droplet-Thymus-nan-24m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.50e-04 | 169 | 51 | 3 | 780fb0050852626062a729dd1b82b0cf61e7e9ca | |
| ToppCell | 3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 9.50e-04 | 169 | 51 | 3 | 2456b3e7776e8a2214972be1b4d66a3ca5480ae0 | |
| ToppCell | Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 9.66e-04 | 170 | 51 | 3 | 45584bd9953257dd28c06ffbbfe4395ce7b1b88d | |
| Drug | Sodium | 1.15e-11 | 84 | 50 | 8 | ctd:D012964 | |
| Drug | Zonisamide | 2.52e-10 | 17 | 50 | 5 | DB00909 | |
| Drug | APETx1, Anthopleura elegantissima | 3.08e-10 | 6 | 50 | 4 | ctd:C475726 | |
| Drug | AC1L1MOZ | 3.24e-09 | 27 | 50 | 5 | CID000031958 | |
| Drug | nefopam | 3.24e-09 | 27 | 50 | 5 | CID000004450 | |
| Drug | tocainide | 5.69e-09 | 30 | 50 | 5 | CID000038945 | |
| Drug | N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide | 9.97e-09 | 3 | 50 | 3 | ctd:C561228 | |
| Drug | Tetrodotoxin | 2.58e-08 | 40 | 50 | 5 | ctd:D013779 | |
| Drug | tetradotoxin | SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A GRIN2A ATP1A1 EDNRB OPRD1 | 2.60e-08 | 428 | 50 | 10 | CID000020382 |
| Drug | Lidocaine | 3.98e-08 | 4 | 50 | 3 | DB00281 | |
| Drug | pilsicainide | 5.33e-08 | 46 | 50 | 5 | CID000004820 | |
| Drug | spiradoline | 5.33e-08 | 46 | 50 | 5 | CID000005620 | |
| Drug | diprafenone | 7.78e-08 | 19 | 50 | 4 | CID000071249 | |
| Drug | NSC7524 | 1.39e-07 | 182 | 50 | 7 | CID000005657 | |
| Drug | triamterene | 1.75e-07 | 58 | 50 | 5 | CID000005546 | |
| Drug | lamotrigine | 2.03e-07 | 116 | 50 | 6 | CID000003878 | |
| Drug | AC1NT1AF | 2.52e-07 | 25 | 50 | 4 | CID005322157 | |
| Drug | Pirmenolum | 2.97e-07 | 26 | 50 | 4 | CID000004853 | |
| Drug | AC1L1CQC | 3.11e-07 | 65 | 50 | 5 | CID000002012 | |
| Drug | bepridil | 3.32e-07 | 126 | 50 | 6 | CID000002351 | |
| Drug | mexiletine | 3.36e-07 | 66 | 50 | 5 | CID000004178 | |
| Drug | disopyramide | 3.36e-07 | 66 | 50 | 5 | CID000003114 | |
| Drug | PbTx-1 | 3.48e-07 | 27 | 50 | 4 | CID006437089 | |
| Drug | dibucaine | 3.91e-07 | 68 | 50 | 5 | CID000003025 | |
| Drug | paraben | 4.05e-07 | 28 | 50 | 4 | CID000007175 | |
| Drug | GBR 12909 | 4.20e-07 | 69 | 50 | 5 | CID000003455 | |
| Drug | T2755 | 4.86e-07 | 71 | 50 | 5 | CID000005514 | |
| Drug | flecainide | 4.86e-07 | 71 | 50 | 5 | CID000003355 | |
| Drug | Cocaine | 5.54e-07 | 8 | 50 | 3 | DB00907 | |
| Drug | 2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate | 5.54e-07 | 8 | 50 | 3 | ctd:C489827 | |
| Drug | sodium | SLC6A2 SLC9A2 UPF2 SCN3A TRPC6 SCN4A SCN5A SCN9A SCN10A TCIRG1 ATP1A1 OPRD1 | 6.81e-07 | 944 | 50 | 12 | CID000000923 |
| Drug | NSC93767 | 7.07e-07 | 32 | 50 | 4 | CID000005658 | |
| Drug | Mexiletine | 8.29e-07 | 9 | 50 | 3 | ctd:D008801 | |
| Drug | 5-hydroxypropafenone | 9.09e-07 | 34 | 50 | 4 | CID000107927 | |
| Drug | bupropion | 9.40e-07 | 81 | 50 | 5 | CID000000444 | |
| Drug | benzocaine | 1.29e-06 | 37 | 50 | 4 | CID000002337 | |
| Drug | aprindine | 1.44e-06 | 38 | 50 | 4 | CID000002218 | |
| Drug | ketamine | 1.61e-06 | 262 | 50 | 7 | CID000003821 | |
| Drug | S-ropivacaine | 1.77e-06 | 40 | 50 | 4 | CID000071273 | |
| Drug | gabapentin | 1.86e-06 | 169 | 50 | 6 | CID000003446 | |
| Drug | riluzole | 2.20e-06 | 174 | 50 | 6 | CID000005070 | |
| Drug | aldosterone | 2.25e-06 | 397 | 50 | 8 | CID000005839 | |
| Drug | propafenone | 2.42e-06 | 98 | 50 | 5 | CID000004932 | |
| Drug | carbamazepine | 2.59e-06 | 179 | 50 | 6 | CID000002554 | |
| Drug | methanethiosulfonate | 3.10e-06 | 103 | 50 | 5 | CID004188587 | |
| Drug | pseudococaine | 3.64e-06 | 570 | 50 | 9 | CID000002826 | |
| Drug | indoxacarb | 4.05e-06 | 49 | 50 | 4 | CID000107720 | |
| Drug | etridiazole | 4.40e-06 | 50 | 50 | 4 | CID000017432 | |
| Drug | Hexylcaine | 4.73e-06 | 2 | 50 | 2 | DB00473 | |
| Drug | Ranolazine | 4.73e-06 | 2 | 50 | 2 | DB00243 | |
| Drug | Phenytoin | 4.73e-06 | 2 | 50 | 2 | DB00252 | |
| Drug | Flecainide | 4.73e-06 | 2 | 50 | 2 | DB01195 | |
| Drug | AC1NSN3X | 6.00e-06 | 54 | 50 | 4 | CID005366189 | |
| Drug | orphenadrine | 6.95e-06 | 56 | 50 | 4 | CID000004601 | |
| Drug | moricizine | 7.94e-06 | 18 | 50 | 3 | CID000034632 | |
| Drug | Scorpion Venoms | 7.94e-06 | 18 | 50 | 3 | ctd:D012604 | |
| Drug | bupivacaine | 8.00e-06 | 125 | 50 | 5 | CID000002474 | |
| Drug | quindine | 8.25e-06 | 219 | 50 | 6 | CID000001065 | |
| Drug | pentobarbital | 9.39e-06 | 224 | 50 | 6 | CID000004737 | |
| Drug | piperidine | 9.69e-06 | 130 | 50 | 5 | CID000008082 | |
| Drug | methylglucamine | 1.05e-05 | 62 | 50 | 4 | CID000004049 | |
| Drug | zonisamide | 1.05e-05 | 62 | 50 | 4 | CID000005734 | |
| Drug | dofetilide | 1.11e-05 | 63 | 50 | 4 | CID000071329 | |
| Drug | saxitoxin | 1.26e-05 | 65 | 50 | 4 | CID000037165 | |
| Drug | resiniferatoxin | 1.34e-05 | 66 | 50 | 4 | CID000104826 | |
| Drug | Dibucaine | 1.42e-05 | 3 | 50 | 2 | DB00527 | |
| Drug | AC1NV9C3 | 1.42e-05 | 3 | 50 | 2 | CID005474846 | |
| Drug | Cytochrophin-4 | 1.42e-05 | 3 | 50 | 2 | CID000126809 | |
| Drug | salbutamol | 1.70e-05 | 146 | 50 | 5 | CID000002083 | |
| Drug | 1, 3-diallylurea | 2.11e-05 | 74 | 50 | 4 | CID000074537 | |
| Drug | imide | 2.11e-05 | 74 | 50 | 4 | CID000443040 | |
| Drug | isofagomine | 2.23e-05 | 75 | 50 | 4 | CID000447607 | |
| Drug | diphenhydramine | 2.23e-05 | 75 | 50 | 4 | CID000003100 | |
| Drug | phenamil | 2.50e-05 | 26 | 50 | 3 | CID000004755 | |
| Drug | lidocaine | 2.64e-05 | 160 | 50 | 5 | CID000003676 | |
| Drug | amiodarone | 2.64e-05 | 160 | 50 | 5 | CID000002156 | |
| Drug | APETx2 protein, Anthopleura elegantissima | 2.83e-05 | 4 | 50 | 2 | ctd:C501880 | |
| Drug | encainide | 3.14e-05 | 28 | 50 | 3 | CID000048040 | |
| Drug | DPI 201-106 | 3.14e-05 | 28 | 50 | 3 | CID000005190 | |
| Drug | QX-314 | 3.17e-05 | 82 | 50 | 4 | CID000003925 | |
| Drug | diethylene glycol | 3.49e-05 | 84 | 50 | 4 | CID000008117 | |
| Drug | oxcarbazepine | 3.88e-05 | 30 | 50 | 3 | CID000034312 | |
| Drug | toluene | 4.06e-05 | 175 | 50 | 5 | CID000001140 | |
| Drug | remifentanil | 4.73e-05 | 32 | 50 | 3 | CID000060814 | |
| Drug | strychnine HCl | 4.76e-05 | 181 | 50 | 5 | CID000005304 | |
| Drug | potassium | SLC9A2 SCN3A SCN4A SCN5A SCN9A SCN10A TCIRG1 GRIN2A ATP1A1 KCNH3 | 5.65e-05 | 1008 | 50 | 10 | CID000000813 |
| Drug | NSC15627 | 5.68e-05 | 34 | 50 | 3 | CID000002073 | |
| Drug | procainamide | 6.00e-05 | 190 | 50 | 5 | CID000004913 | |
| Drug | propofol | 6.15e-05 | 191 | 50 | 5 | CID000004943 | |
| Drug | trimethoprim | 6.64e-05 | 99 | 50 | 4 | CID000005578 | |
| Drug | isradipine | 6.91e-05 | 100 | 50 | 4 | CID000003784 | |
| Drug | fenpropathrin | 7.05e-05 | 6 | 50 | 2 | ctd:C044267 | |
| Drug | sipatrigine | 7.35e-05 | 37 | 50 | 3 | CID000060803 | |
| Drug | AC1NPPZW | 7.75e-05 | 103 | 50 | 4 | CID005183170 | |
| Drug | N-bromoacetamide | 7.96e-05 | 38 | 50 | 3 | CID000004353 | |
| Drug | ranolazine | 8.61e-05 | 39 | 50 | 3 | CID000056959 | |
| Drug | pyraclofos | 8.67e-05 | 106 | 50 | 4 | CID000093460 | |
| Drug | racemethorphan | 8.99e-05 | 107 | 50 | 4 | CID000003008 | |
| Drug | verapamil | 9.19e-05 | 490 | 50 | 7 | CID000002520 | |
| Drug | Orphenadrine | 9.86e-05 | 7 | 50 | 2 | DB01173 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 1.66e-18 | 10 | 46 | 7 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 1.66e-18 | 10 | 46 | 7 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 1.09e-17 | 12 | 46 | 7 | DOID:0060170 (implicated_via_orthology) | |
| Disease | epilepsy (implicated_via_orthology) | 3.55e-12 | 163 | 46 | 9 | DOID:1826 (implicated_via_orthology) | |
| Disease | Epilepsy | 7.62e-07 | 109 | 46 | 5 | C0014544 | |
| Disease | Early Infantile Epileptic Encephalopathy 6 | 2.38e-06 | 2 | 46 | 2 | C4551549 | |
| Disease | anxiety disorder (implicated_via_orthology) | 5.35e-06 | 22 | 46 | 3 | DOID:2030 (implicated_via_orthology) | |
| Disease | Cluttering | 7.13e-06 | 3 | 46 | 2 | C0009090 | |
| Disease | Dyslalia | 7.13e-06 | 3 | 46 | 2 | C3495145 | |
| Disease | B Virus Infection | 7.13e-06 | 3 | 46 | 2 | C0037140 | |
| Disease | Postherpetic neuralgia | 7.13e-06 | 3 | 46 | 2 | C0032768 | |
| Disease | Herpesviridae Infections | 7.13e-06 | 3 | 46 | 2 | C0019372 | |
| Disease | Aprosodia | 7.13e-06 | 3 | 46 | 2 | C0233726 | |
| Disease | Rhinolalia | 7.13e-06 | 3 | 46 | 2 | C0751513 | |
| Disease | Dysglossia | 7.13e-06 | 3 | 46 | 2 | C0751512 | |
| Disease | Verbal Fluency Disorders | 7.13e-06 | 3 | 46 | 2 | C0751514 | |
| Disease | PAROXYSMAL EXTREME PAIN DISORDER | 7.13e-06 | 3 | 46 | 2 | C1833661 | |
| Disease | Primary Erythermalgia | 7.13e-06 | 3 | 46 | 2 | C0014805 | |
| Disease | Epilepsy, Cryptogenic | 8.27e-06 | 82 | 46 | 4 | C0086237 | |
| Disease | Awakening Epilepsy | 8.27e-06 | 82 | 46 | 4 | C0751111 | |
| Disease | Aura | 8.27e-06 | 82 | 46 | 4 | C0236018 | |
| Disease | Speech Disorders | 1.42e-05 | 4 | 46 | 2 | C0037822 | |
| Disease | Brugada ECG Pattern | 1.42e-05 | 4 | 46 | 2 | C1721096 | |
| Disease | Hereditary Sensory Autonomic Neuropathy, Type 5 | 4.97e-05 | 7 | 46 | 2 | C0020075 | |
| Disease | electrocardiography, PR interval | 4.97e-05 | 7 | 46 | 2 | EFO_0004327, EFO_0004462 | |
| Disease | Congenital Pain Insensitivity | 4.97e-05 | 7 | 46 | 2 | C0002768 | |
| Disease | Early Childhood Epilepsy, Myoclonic | 6.62e-05 | 8 | 46 | 2 | C0393695 | |
| Disease | Idiopathic Myoclonic Epilepsy | 6.62e-05 | 8 | 46 | 2 | C0338478 | |
| Disease | Symptomatic Myoclonic Epilepsy | 6.62e-05 | 8 | 46 | 2 | C0338479 | |
| Disease | Myoclonic Encephalopathy | 6.62e-05 | 8 | 46 | 2 | C0438414 | |
| Disease | Benign Infantile Myoclonic Epilepsy | 6.62e-05 | 8 | 46 | 2 | C0751120 | |
| Disease | Ataxias, Hereditary | 6.62e-05 | 8 | 46 | 2 | C0004138 | |
| Disease | Myoclonic Absence Epilepsy | 6.62e-05 | 8 | 46 | 2 | C0393703 | |
| Disease | Myoclonic Epilepsy | 8.50e-05 | 9 | 46 | 2 | C0014550 | |
| Disease | supraventricular ectopy | 8.50e-05 | 9 | 46 | 2 | EFO_0009277 | |
| Disease | Generalized Epilepsy with Febrile Seizures Plus | 8.50e-05 | 9 | 46 | 2 | C3502809 | |
| Disease | Epilepsy, Myoclonic, Infantile | 1.06e-04 | 10 | 46 | 2 | C0917800 | |
| Disease | Myoclonic Astatic Epilepsy | 1.30e-04 | 11 | 46 | 2 | C0393702 | |
| Disease | Brugada Syndrome 1 | 1.83e-04 | 13 | 46 | 2 | C4551804 | |
| Disease | Infantile Severe Myoclonic Epilepsy | 1.83e-04 | 13 | 46 | 2 | C0751122 | |
| Disease | T wave morphology measurement | 2.14e-04 | 14 | 46 | 2 | EFO_0008398 | |
| Disease | P wave duration | 2.46e-04 | 15 | 46 | 2 | EFO_0005094 | |
| Disease | Neuralgia, Supraorbital | 2.81e-04 | 16 | 46 | 2 | C0038870 | |
| Disease | Neuralgia, Iliohypogastric Nerve | 2.81e-04 | 16 | 46 | 2 | C0423712 | |
| Disease | Neuralgia, Perineal | 2.81e-04 | 16 | 46 | 2 | C0423711 | |
| Disease | Neuralgia | 2.81e-04 | 16 | 46 | 2 | C0027796 | |
| Disease | Romano-Ward Syndrome | 2.81e-04 | 16 | 46 | 2 | C0035828 | |
| Disease | Neuralgia, Atypical | 2.81e-04 | 16 | 46 | 2 | C0234247 | |
| Disease | Neuralgia, Stump | 2.81e-04 | 16 | 46 | 2 | C0234249 | |
| Disease | Paroxysmal Nerve Pain | 2.81e-04 | 16 | 46 | 2 | C0751373 | |
| Disease | Nerve Pain | 2.81e-04 | 16 | 46 | 2 | C0751372 | |
| Disease | Neuralgia, Ilioinguinal | 2.81e-04 | 16 | 46 | 2 | C0751371 | |
| Disease | Neuralgia, Vidian | 2.81e-04 | 16 | 46 | 2 | C0042656 | |
| Disease | Brugada syndrome | 4.00e-04 | 19 | 46 | 2 | MONDO_0015263 | |
| Disease | Intellectual Disability | 6.41e-04 | 447 | 46 | 5 | C3714756 | |
| Disease | Brugada Syndrome (disorder) | 6.42e-04 | 24 | 46 | 2 | C1142166 | |
| Disease | Alcoholic Intoxication, Chronic | 8.05e-04 | 268 | 46 | 4 | C0001973 | |
| Disease | Bipolar Disorder | 8.58e-04 | 477 | 46 | 5 | C0005586 | |
| Disease | attention deficit hyperactivity disorder (implicated_via_orthology) | 8.76e-04 | 28 | 46 | 2 | DOID:1094 (implicated_via_orthology) | |
| Disease | cardiovascular age measurement | 9.40e-04 | 29 | 46 | 2 | EFO_0803380 | |
| Disease | hypertension (implicated_via_orthology) | 1.06e-03 | 128 | 46 | 3 | DOID:10763 (implicated_via_orthology) | |
| Disease | heart function measurement | 1.29e-03 | 34 | 46 | 2 | EFO_0004311 | |
| Disease | serine measurement | 1.37e-03 | 35 | 46 | 2 | EFO_0009774 | |
| Disease | Hereditary hearing loss and deafness | 1.54e-03 | 146 | 46 | 3 | cv:C0236038 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| FWLSWGLTYICFIFI | 176 | Q8WWZ4 | |
| TEKACWLRVDNYFIW | 991 | O94910 | |
| TAKDWWLFSFYFCLP | 271 | P24530 | |
| WKRRWFILTDNCLYY | 276 | Q9UIA0 | |
| PCIVIKFRYLWLFWF | 711 | Q96F81 | |
| KFRYLWLFWFLALTV | 716 | Q96F81 | |
| KFRYIWICWFAALAA | 701 | A7MBM2 | |
| VFALLAHWVACVWFY | 366 | Q9ULD8 | |
| RKTYFFVGIWCWRFD | 386 | Q9H306 | |
| YAKLVILCWVCGFLW | 156 | Q8NH07 | |
| LREKFWEFYKADWCV | 136 | Q567V2 | |
| TWWFCAFPYSLLIFV | 986 | P05023 | |
| WFRSWGYVLLIVLFC | 486 | Q9H9K5 | |
| WADRQRDCLWKFFFP | 346 | Q2LD37 | |
| WYLVVALWCFFKDVE | 6 | Q7Z5P9 | |
| VKACLWVFLWRFTIY | 56 | P28328 | |
| RGCYFVLDWLQKTYW | 171 | Q9Y4W2 | |
| SWYWDTVTKICVFLF | 206 | P41143 | |
| FAVVWLAIWAVLCFF | 226 | Q9ULW2 | |
| LNVYFVKVAWAWTFC | 56 | Q8N6M3 | |
| YRFRCLNVILWLGFW | 146 | P35575 | |
| YWRDLCLDFQFWKQL | 351 | Q9UF56 | |
| WFFCTAFRKFIWVIL | 151 | O15121 | |
| YAKLVILCWVCGFLW | 156 | Q8NG94 | |
| KLDCFLVYFQRYVWW | 941 | Q9HAU5 | |
| HSNLWFAAWLKVFYC | 106 | P59535 | |
| FKFWVWESVIYLCAA | 276 | P59551 | |
| YWRLCWKFVSPAFLL | 516 | P23975 | |
| DVQLWLSYVAFCKKW | 106 | Q9NYH9 | |
| WKRFCFWKATRSYLQ | 976 | A5PLK6 | |
| TFCWRVFCAWDYLIG | 266 | Q7Z5M5 | |
| VYFTNAWCWLDFLIV | 1091 | P35499 | |
| LWKRRWFVLADYCLF | 181 | Q6IQ23 | |
| YFTNAWCWLDFLIVD | 1266 | Q14524 | |
| RFAHKFLIWNCSPYW | 716 | Q15858 | |
| KTYFTNAWCWLDFLI | 1251 | Q15858 | |
| LWVGWNAFIICFYLE | 71 | Q4KMZ8 | |
| TYFTNAWCWLDFLIV | 1266 | Q9NY46 | |
| PCWYKFSNIFLIWDC | 736 | P35498 | |
| FCFRWLLIWFKREFP | 491 | Q9HA65 | |
| YAVSWCFMFSIWRFA | 201 | Q6ZRR5 | |
| CVRALSIQRLWYFWF | 51 | Q96AW1 | |
| LIGWTWYFLEIVFCK | 131 | Q9NRZ7 | |
| ALTEWLRFYNKWLYC | 131 | Q8NCC5 | |
| LRFYNKWLYCCLWIV | 136 | Q8NCC5 | |
| WAFVCFTLAFCLMWR | 391 | Q9UBY0 | |
| KKYFTNAWCWLDFLI | 1211 | Q9Y5Y9 | |
| FWVKVASCWACVLLY | 466 | A6NH21 | |
| PCWYKFANTFLIWEC | 721 | Q9UQD0 | |
| FVKFFTNAWCWLDFL | 1256 | Q9UQD0 | |
| AWRLLKNYYKWRAEC | 66 | P49638 | |
| TWSACYWKDILRIQF | 236 | Q96K49 | |
| EWKFARAKLWFSYFE | 741 | Q9Y210 | |
| FLVIYKWLCVWAARA | 586 | Q13488 | |
| ILVWLTAIVLFCWFY | 636 | O76024 | |
| IWEHLFYWKLRFCFT | 836 | Q12879 |