Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A7 SLC4A8	1.23e-04	6	58	2	GO:0008510
GeneOntologyMolecularFunction	hormone binding	CALR IDE ECE1 LEPR	2.29e-04	103	58	4	GO:0042562
GeneOntologyBiologicalProcess	response to endoplasmic reticulum stress	HSP90B1 CLGN MAN1A1 RASGRF2 CALR EIF4G1 EIF2AK3 ITPR1	1.43e-06	295	57	8	GO:0034976
GeneOntologyBiologicalProcess	response to flavonoid	NQO1 IP6K2	7.50e-06	2	57	2	GO:1905395
GeneOntologyBiologicalProcess	ERAD pathway	HSP90B1 CLGN MAN1A1 CALR EIF2AK3	1.94e-05	119	57	5	GO:0036503
GeneOntologyBiologicalProcess	positive regulation of binding	EIF4G1 HMGB2 IDE EIF2AK3 IP6K2	1.06e-04	170	57	5	GO:0051099
GeneOntologyCellularComponent	sarcoplasmic reticulum	HSP90B1 CALR SYNE2 ITPR1	1.12e-04	88	59	4	GO:0016529
GeneOntologyCellularComponent	sarcoplasmic reticulum lumen	HSP90B1 CALR	2.78e-04	9	59	2	GO:0033018
GeneOntologyCellularComponent	smooth endoplasmic reticulum	HSP90B1 CALR ITPR1	2.97e-04	46	59	3	GO:0005790
GeneOntologyCellularComponent	sarcoplasm	HSP90B1 CALR SYNE2 ITPR1	3.03e-04	114	59	4	GO:0016528
GeneOntologyCellularComponent	endoplasmic reticulum quality control compartment	CALR EIF2AK3	1.04e-03	17	59	2	GO:0044322
Domain	-	CLGN CALR	2.64e-05	3	56	2	2.10.250.10
Domain	CALRETICULIN_REPEAT	CLGN CALR	2.64e-05	3	56	2	PS00805
Domain	Calret/calnex	CLGN CALR	5.28e-05	4	56	2	IPR001580
Domain	CALRETICULIN_1	CLGN CALR	5.28e-05	4	56	2	PS00803
Domain	CALRETICULIN_2	CLGN CALR	5.28e-05	4	56	2	PS00804
Domain	Calret/calnex_CS	CLGN CALR	5.28e-05	4	56	2	IPR018124
Domain	Calreticulin	CLGN CALR	5.28e-05	4	56	2	PF00262
Domain	Calreticulin/calnexin_P_dom	CLGN CALR	8.78e-05	5	56	2	IPR009033
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A8	1.84e-04	7	56	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A8	1.84e-04	7	56	2	PS00219
Domain	Peptidase_M13	MMEL1 ECE1	1.84e-04	7	56	2	PF01431
Domain	Peptidase_M13_C	MMEL1 ECE1	1.84e-04	7	56	2	IPR018497
Domain	Peptidase_M13	MMEL1 ECE1	1.84e-04	7	56	2	IPR000718
Domain	Peptidase_M13_N	MMEL1 ECE1	1.84e-04	7	56	2	PF05649
Domain	Peptidase_M13_N	MMEL1 ECE1	1.84e-04	7	56	2	IPR008753
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A8	3.14e-04	9	56	2	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A8	3.14e-04	9	56	2	PF07565
Domain	-	SLC4A7 SLC4A8	3.14e-04	9	56	2	3.40.1100.10
Domain	HCO3_cotransp	SLC4A7 SLC4A8	3.91e-04	10	56	2	PF00955
Domain	HCO3_transpt_C	SLC4A7 SLC4A8	3.91e-04	10	56	2	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A7 SLC4A8	3.91e-04	10	56	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A7 SLC4A8	3.91e-04	10	56	2	IPR003020
Domain	HMG_box	SOX5 HMGB2 SSRP1	5.38e-04	53	56	3	PF00505
Domain	HMG_BOX_2	SOX5 HMGB2 SSRP1	5.68e-04	54	56	3	PS50118
Domain	HMG	SOX5 HMGB2 SSRP1	5.68e-04	54	56	3	SM00398
Domain	WWE	DDHD2 ZC3HAV1	5.72e-04	12	56	2	PS50918
Domain	WWE	DDHD2 ZC3HAV1	5.72e-04	12	56	2	PF02825
Domain	WWE-dom	DDHD2 ZC3HAV1	5.72e-04	12	56	2	IPR004170
Domain	-	SOX5 HMGB2 SSRP1	6.00e-04	55	56	3	1.10.30.10
Domain	HMG_box_dom	SOX5 HMGB2 SSRP1	9.78e-04	65	56	3	IPR009071
Domain	Chromo_domain	CDYL2 CHD8	2.34e-03	24	56	2	IPR023780
Domain	Chromo	CDYL2 CHD8	2.74e-03	26	56	2	PF00385
Domain	CHROMO_1	CDYL2 CHD8	3.17e-03	28	56	2	PS00598
Domain	CHROMO_2	CDYL2 CHD8	3.17e-03	28	56	2	PS50013
Domain	Chromodomain-like	CDYL2 CHD8	4.13e-03	32	56	2	IPR016197
Domain	Chromo/shadow_dom	CDYL2 CHD8	4.39e-03	33	56	2	IPR000953
Domain	CHROMO	CDYL2 CHD8	4.39e-03	33	56	2	SM00298
Domain	AAA	IQCA1 VPS4A	4.66e-03	34	56	2	PS00674
Domain	ER_TARGET	HSP90B1 CALR	8.75e-03	47	56	2	PS00014
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	ABCC1 HSP90B1 CLGN SLC4A7 CALR TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	6.17e-09	468	59	10	31056421
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 HSP90B1 PTPN13 SLC4A7 CALR TEX2 COX4I1 SYNE2 ANKRD11 CENPV DDHD2 SSRP1 EIF2AK3 ITPR1 ZC3HAV1	1.84e-08	1487	59	15	33957083
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HSP90B1 SLC4A7 TEX2 COX4I1 SYNE2 CENPV UQCC2 IDE DDHD2 SSRP1 LARS2 EIF2AK3 ITPR1 ZC3HAV1	1.51e-07	1496	59	14	32877691
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	DOCK5 CASP8AP2 ABCC1 HSP90B1 TEX2 SYNE2 EIF4G1 SSRP1 ECE1 ITPR1	5.21e-07	754	59	10	35906200
Pubmed	Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.	HSP90B1 CALR EIF2AK3	2.08e-06	15	59	3	17090218
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PTPN13 SLC4A7 TEX2 SYNE2 ECE1 EIF2AK3 ITPR1 ZC3HAV1	2.13e-06	504	59	8	34432599
Pubmed	Identification of Up- and Down-Regulated Proteins in Pemetrexed-Resistant Human Lung Adenocarcinoma: Flavin Reductase and Calreticulin Play Key Roles in the Development of Pemetrexed-Associated Resistance.	CALR NQO1	2.83e-06	2	59	2	26452990
Pubmed	Mutational analysis of FLASH and PTPN13 genes in colorectal carcinomas.	CASP8AP2 PTPN13	2.83e-06	2	59	2	18038312
Pubmed	NAD(P)H quinone-oxydoreductase 1 protects eukaryotic translation initiation factor 4GI from degradation by the proteasome.	EIF4G1 NQO1	2.83e-06	2	59	2	20028737
Pubmed	Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing.	DOCK5 LEPR	2.83e-06	2	59	2	33627322
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HSP90B1 CALR VPS4A COX4I1 EIF4G1 RBM5 CC2D2A CENPV IDE PAK1IP1 SSRP1 ZC3HAV1	4.01e-06	1425	59	12	30948266
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	ABCC1 HSP90B1 PTPN13 CLGN SLC4A7 CALR CENPV ECE1 EIF2AK3 ZC3HAV1	4.20e-06	952	59	10	38569033
Pubmed	Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress.	HSP90B1 EIF2AK3	8.48e-06	3	59	2	11907036
Pubmed	Ovalbumin-derived precursor peptides are transferred sequentially from gp96 and calreticulin to MHC class I in the endoplasmic reticulum.	HSP90B1 CALR	8.48e-06	3	59	2	20410492
Pubmed	Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.	SOX5 LEPR	8.48e-06	3	59	2	28585545
Pubmed	A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.	VAV3 ITPR1	8.48e-06	3	59	2	19429868
Pubmed	Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.	IDE ECE1	8.48e-06	3	59	2	20663017
Pubmed	Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.	SLC4A7 SLC4A8	8.48e-06	3	59	2	14736710
Pubmed	Accumulation of murine amyloid-β mimics early Alzheimer's disease.	ABCC1 MMEL1	8.48e-06	3	59	2	25991605
Pubmed	The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.	SLC4A7 SLC4A8	8.48e-06	3	59	2	12444018
Pubmed	HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1.	CALR HMGB2	8.48e-06	3	59	2	39354146
Pubmed	PERK in POMC neurons connects celastrol with metabolism.	EIF2AK3 LEPR	8.48e-06	3	59	2	34549728
Pubmed	PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy.	ABCC1 EIF2AK3	8.48e-06	3	59	2	28499449
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ERCC4 CHD8 PAK1IP1 SSRP1 EIF2AK3 ITPR1 ZC3HAV1	9.57e-06	440	59	7	34244565
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PTPN13 SLC4A7 CEP85L TEX2 SYNE2 EIF4G1 ANKRD11 SSRP1 ZC3HAV1	1.39e-05	861	59	9	36931259
Pubmed	Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.	LPIN2 LEPR	1.69e-05	4	59	2	19136718
Pubmed	The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3.	SLC4A7 SLC4A8	1.69e-05	4	59	2	12403779
Pubmed	DOCK5 regulates energy balance and hepatic insulin sensitivity by targeting mTORC1 signaling.	DOCK5 LEPR	1.69e-05	4	59	2	31885214
Pubmed	The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis.	RASGRF2 VAV3	1.69e-05	4	59	2	20011522
Pubmed	Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues.	SLC4A7 SLC4A8	1.69e-05	4	59	2	17715183
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	PTPN13 SLC4A7 CALR SYNE2 DDHD2 ECE1	1.79e-05	322	59	6	26514267
Pubmed	The unfolded protein response: integrating stress signals through the stress sensor IRE1α.	HSP90B1 CALR EIF2AK3	2.02e-05	31	59	3	22013210
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ABCC1 HSP90B1 CLGN CALR VPS4A COX4I1 SYNE2 EIF4G1 SSRP1 ITPR1 ZC3HAV1	2.65e-05	1440	59	11	30833792
Pubmed	Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.	SLC4A7 SLC4A8	2.82e-05	5	59	2	23500099
Pubmed	Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.	HSP90B1 CALR	2.82e-05	5	59	2	20520781
Pubmed	A novel von Willebrand disease-causing mutation (Arg273Trp) in the von Willebrand factor propeptide that results in defective multimerization and secretion.	HSP90B1 CALR	2.82e-05	5	59	2	10887119
Pubmed	Comparative proteomics-network analysis of proteins responsible for ursolic acid-induced cytotoxicity in colorectal cancer cells.	HSP90B1 CALR	2.82e-05	5	59	2	28347227
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PTPN13 SLC4A7 COX4I1 EIF4G1 ANKRD11 RBM5 CDYL2 CHD8 PAK1IP1 SSRP1 ZC3HAV1	3.78e-05	1497	59	11	31527615
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	ABCC1 HSP90B1 CLGN SLC4A7 SYNE2 ZC3HAV1	4.20e-05	375	59	6	32788342
Pubmed	Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state.	HSP90B1 CALR	4.23e-05	6	59	2	9694898
Pubmed	Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.	FMO3 EIF2AK3	4.23e-05	6	59	2	31543404
Pubmed	A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.	SOX5 MMEL1	4.23e-05	6	59	2	22197933
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	PTPN13 LPIN2 RBM5 CHD8 LARS2	4.72e-05	232	59	5	25515538
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	HSP90B1 PTPN13 SLC4A7 CALR TEX2 SYNE2 HMGB2 SSRP1 ZC3HAV1	4.73e-05	1007	59	9	34597346
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SLC4A7 TEX2 SYNE2 EIF4G1 EIF2AK3 ITPR1 ZC3HAV1	4.89e-05	568	59	7	37774976
Pubmed	Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival.	CALR EIF2AK3	5.91e-05	7	59	2	14517290
Pubmed	Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B.	HSP90B1 CALR	5.91e-05	7	59	2	12397072
Pubmed	Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.	LEPR ITPR1	5.91e-05	7	59	2	22495310
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DOCK5 P4HA2 PTPN13 CLGN CALR VPS4A UQCC2 SSRP1 FYB2 ZC3HAV1	6.96e-05	1321	59	10	27173435
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	P4HA2 HSP90B1 CALR EIF4G1 SSRP1 ZC3HAV1	7.65e-05	418	59	6	35338135
Pubmed	Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss.	HSP90B1 CALR	7.87e-05	8	59	2	30188326
Pubmed	GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development.	HSP90B1 CALR	1.01e-04	9	59	2	16847323
Pubmed	Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.	EIF4G1 EIF2AK3	1.26e-04	10	59	2	12388085
Pubmed	Signaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain.	CALR ITPR1	1.26e-04	10	59	2	15579147
Pubmed	Mitochondrial Raf1 Regulates Glutamine Catabolism.	HSP90B1 PTPN13 CALR NQO1 ZC3HAV1	1.31e-04	288	59	5	38496616
Pubmed	Defining the membrane proteome of NK cells.	ABCC1 HSP90B1 MAN1A1 CALR COX4I1 EIF4G1 ECE1 EIF2AK3 ITPR1	1.46e-04	1168	59	9	19946888
Pubmed	Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse.	HSP90B1 CALR	1.54e-04	11	59	2	17913437
Pubmed	Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis.	HSP90B1 CALR EIF4G1 ZC3HAV1	1.57e-04	159	59	4	36762613
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	P4HA2 HSP90B1 SSRP1 ZC3HAV1	1.65e-04	161	59	4	32572027
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCC1 P4HA2 HSP90B1 CLGN MAN1A1 CALR ECE1 EIF2AK3 ITPR1	1.80e-04	1201	59	9	35696571
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	P4HA2 HSP90B1 ERCC4 SLC4A7 MAN1A1 CALR COX4I1 EIF4G1 CHD8	1.82e-04	1203	59	9	29180619
Pubmed	Genome-wide association study of conduct disorder symptomatology.	ERCC4 CC2D2A	1.85e-04	12	59	2	20585324
Pubmed	Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease.	MMEL1 ECE1	1.85e-04	12	59	2	22027013
Pubmed	Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.	CALR COX4I1	1.85e-04	12	59	2	17923681
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	COX4I1 RBM5 UQCC2 CHD8 ECE1 TSEN2 EIF2AK3 IP6K2 ITPR1	1.96e-04	1215	59	9	15146197
Pubmed	Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.	P4HA2 HSP90B1 CALR ZC3HAV1	2.22e-04	174	59	4	32149426
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	CLGN SLC4A7 CALR EIF2AK3	2.32e-04	176	59	4	28692057
Pubmed	Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.	RBM5 CHD8 EIF2AK3	2.44e-04	71	59	3	36305789
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ABCC1 MAP9 PTPN13 CEP85L CALR UQCC2 IDE	2.81e-04	754	59	7	33060197
Pubmed	Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia.	ERCC4 NQO1	2.93e-04	15	59	2	11895912
Pubmed	Satb2 is required for the regionalization of retrosplenial cortex.	SOX5 MAN1A1	2.93e-04	15	59	2	31666685
Pubmed	The endoplasmic reticulum stress response in aging and age-related diseases.	HSP90B1 EIF2AK3	2.93e-04	15	59	2	22934019
Pubmed	Large-scale genotyping identifies 41 new loci associated with breast cancer risk.	SLC4A7 CDYL2 ITPR1	2.99e-04	76	59	3	23535729
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	TEX2 SYNE2 EIF2AK3 ZC3HAV1	3.17e-04	191	59	4	31177093
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	ABCC1 PTPN13 ERCC4 NQO1 LEPR	3.26e-04	351	59	5	20453000
Pubmed	Genome-wide association analysis identifies multiple loci related to resting heart rate.	SOX5 CEP85L	3.34e-04	16	59	2	20639392
Pubmed	No replication of genetic association between candidate polymorphisms and Alzheimer's disease.	IDE ECE1	3.34e-04	16	59	2	19889475
Pubmed	Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma.	NQO1 IDE	3.34e-04	16	59	2	27125672
Pubmed	Gene expression analysis of the embryonic subplate.	SYNE2 HMGB2 IDE ITPR1	3.49e-04	196	59	4	21862448
Pubmed	Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.	P4HA2 HSP90B1 CALR ELMOD1	3.56e-04	197	59	4	23686814
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	HSP90B1 SYNE2 CFAP58 CHD8	3.56e-04	197	59	4	20811636
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ABCC1 HSP90B1 PTPN13 CALR COX4I1 SYNE2 IDE ITPR1	3.78e-04	1049	59	8	27880917
Pubmed	Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.	CALR EIF2AK3	3.79e-04	17	59	2	32938586
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	ABCC1 SLC4A7 SLC4A8 CENPV EIF2AK3	4.20e-04	371	59	5	15747579
Pubmed	The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest.	CALR SSRP1	4.75e-04	19	59	2	16522924
Pubmed	Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.	HSP90B1 LEPR	4.75e-04	19	59	2	32888949
Pubmed	Molecular evolution of Sry and Sox gene.	SOX5 SSRP1	5.27e-04	20	59	2	11404013
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	HSP90B1 CENPV HMGB2 CHD8 SSRP1	5.51e-04	394	59	5	27248496
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	HSP90B1 EIF4G1 RBM5 CENPV PAK1IP1 SSRP1 ZC3HAV1	5.63e-04	847	59	7	35850772
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	CALR COX4I1 EIF4G1 SSRP1 LARS2 ZC3HAV1	5.67e-04	607	59	6	39147351
Pubmed	Ubiquitin-protein ligase E3C maintains non-small-cell lung cancer stemness by targeting AHNAK-p53 complex.	HSP90B1 CALR	5.82e-04	21	59	2	30503554
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	ABCC1 P4HA2 HSP90B1 CALR COX4I1 NQO1 LARS2	6.11e-04	859	59	7	31536960
Pubmed	Quantitative trait loci for body size components in mice.	SOX5 RASGRF2 ITPR1	6.29e-04	98	59	3	16783635
Pubmed	Mapping wild-type and R345W fibulin-3 intracellular interactomes.	HSP90B1 CALR	6.39e-04	22	59	2	27777122
Pubmed	A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis.	VPS4A NQO1	6.39e-04	22	59	2	12417987
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MAP9 HSP90B1 SYNE2 EIF4G1 RBM5 CC2D2A HMGB2 SSRP1 ECE1	6.84e-04	1442	59	9	35575683
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	SYNE2 EIF4G1 CHD8	6.87e-04	101	59	3	26949739
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	ABCC1 PTPN13 ITPR1	7.48e-04	104	59	3	31240132
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	HSP90B1 SLC4A7 CALR VPS4A COX4I1	7.51e-04	422	59	5	27342126
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	ABCC1 SLC4A8 LEPR	7.69e-04	105	59	3	30280653
Interaction	RND2 interactions	ABCC1 PTPN13 SLC4A7 TEX2 VPS4A SYNE2 SSRP1 EIF2AK3 ITPR1	3.69e-06	440	57	9	int:RND2
Interaction	DERL1 interactions	ABCC1 HSP90B1 SLC4A7 TEX2 SYNE2 DDHD2 EIF2AK3 ITPR1 ZC3HAV1	4.68e-06	453	57	9	int:DERL1
Interaction	GJD3 interactions	ABCC1 PTPN13 CLGN SLC4A7 TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	4.76e-06	454	57	9	int:GJD3
Interaction	SEC61B interactions	ABCC1 P4HA2 HSP90B1 CLGN SLC4A7 CALR TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	8.01e-06	763	57	11	int:SEC61B
Interaction	HSD17B11 interactions	CLGN SLC4A7 TEX2 SYNE2 DDHD2 EIF2AK3 ITPR1 ZC3HAV1	1.32e-05	390	57	8	int:HSD17B11
Interaction	PXMP2 interactions	HSP90B1 CALR TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	1.39e-05	281	57	7	int:PXMP2
Interaction	OTULINL interactions	ABCC1 CLGN SLC4A7 TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	1.73e-05	405	57	8	int:OTULINL
Interaction	BCAP31 interactions	HSP90B1 CLGN SLC4A7 CALR TEX2 COX4I1 SYNE2 EIF2AK3 ITPR1	2.33e-05	554	57	9	int:BCAP31
Interaction	ATP2A1 interactions	ABCC1 CLGN TEX2 SYNE2 DDHD2 EIF2AK3 ITPR1 ZC3HAV1	2.37e-05	423	57	8	int:ATP2A1
Interaction	TMPRSS4 interactions	HSP90B1 CLGN TEX2 SYNE2 ECE1 EIF2AK3 ITPR1	2.83e-05	314	57	7	int:TMPRSS4
Interaction	SYNE3 interactions	P4HA2 HSP90B1 CLGN CALR TEX2 SYNE2 EIF2AK3 ZC3HAV1	3.34e-05	444	57	8	int:SYNE3
Interaction	SSR1 interactions	CLGN SLC4A7 TEX2 SYNE2 HMGB2 EIF2AK3 ITPR1 ZC3HAV1	3.86e-05	453	57	8	int:SSR1
Interaction	TMT1A interactions	SLC4A7 TEX2 SYNE2 DDHD2 EIF2AK3 ITPR1 ZC3HAV1	6.60e-05	359	57	7	int:TMT1A
Interaction	SEC62 interactions	HSP90B1 CLGN SLC4A7 TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	8.38e-05	506	57	8	int:SEC62
Interaction	CLEC4D interactions	CLGN CALR SYNE2 CENPV SSRP1 EIF2AK3	9.30e-05	261	57	6	int:CLEC4D
Interaction	RHOA interactions	ABCC1 PTPN13 SLC4A7 RASGRF2 TEX2 COX4I1 SYNE2 VAV3 ELMOD1 EIF2AK3 ITPR1 ZC3HAV1	1.09e-04	1199	57	12	int:RHOA
Interaction	LRRC59 interactions	P4HA2 HSP90B1 CLGN SLC4A7 CALR TEX2 SYNE2 EIF4G1 EIF2AK3 ZC3HAV1	1.15e-04	845	57	10	int:LRRC59
Interaction	LGALS8 interactions	ABCC1 HSP90B1 SLC4A7 HMGB2 ECE1	1.32e-04	174	57	5	int:LGALS8
Interaction	DNAJC25 interactions	SLC4A7 TEX2 SYNE2 EIF2AK3 ITPR1 ZC3HAV1	1.47e-04	284	57	6	int:DNAJC25
Interaction	TMPRSS11B interactions	ABCC1 CLGN CALR SYNE2 ECE1 EIF2AK3 ITPR1	1.65e-04	416	57	7	int:TMPRSS11B
Interaction	CANX interactions	ABCC1 HSP90B1 CLGN SLC4A7 CALR TEX2 COX4I1 HMGB2 ECE1 EIF2AK3 ITPR1 ZC3HAV1	1.75e-04	1261	57	12	int:CANX
Interaction	STX4 interactions	ABCC1 SLC4A7 TXLNB TEX2 SYNE2 EIF2AK3 ZC3HAV1	1.96e-04	428	57	7	int:STX4
Interaction	RAB35 interactions	ABCC1 PTPN13 SLC4A7 TEX2 SYNE2 ECE1 EIF2AK3 ZC3HAV1	1.97e-04	573	57	8	int:RAB35
Interaction	LMTK3 interactions	CALR CENPV HMGB2 SSRP1	2.06e-04	103	57	4	int:LMTK3
Interaction	RHOG interactions	DOCK5 ABCC1 SLC4A7 SYNE2 VAV3 DDHD2 LARS2 EIF2AK3 ITPR1 ZC3HAV1	2.10e-04	910	57	10	int:RHOG
Interaction	CKAP4 interactions	HSP90B1 SLC4A7 TEX2 COX4I1 SYNE2 VAV3 EIF2AK3 ZC3HAV1	2.46e-04	592	57	8	int:CKAP4
Interaction	MARCKS interactions	ABCC1 HSP90B1 PTPN13 SLC4A7 CALR COX4I1 SSRP1 ZC3HAV1	2.72e-04	601	57	8	int:MARCKS
Interaction	KDM4D interactions	CLGN RBM5 HMGB2	2.80e-04	45	57	3	int:KDM4D
Interaction	BIRC3 interactions	HSP90B1 CALR VPS4A COX4I1 EIF4G1 RBM5 CC2D2A CENPV IDE PAK1IP1 SSRP1 ZC3HAV1	2.94e-04	1334	57	12	int:BIRC3
Interaction	RAC3 interactions	ABCC1 PTPN13 SLC4A7 ANKRD11 ECE1 EIF2AK3 ITPR1 ZC3HAV1	3.32e-04	619	57	8	int:RAC3
Interaction	TRRAP interactions	DOCK5 CASP8AP2 ABCC1 HSP90B1 TEX2 EIF4G1 SSRP1 ECE1 ITPR1	3.47e-04	790	57	9	int:TRRAP
Interaction	SIRT6 interactions	ERCC4 NQO1 CHD8 PAK1IP1 SSRP1 EIF2AK3 ITPR1 ZC3HAV1	3.65e-04	628	57	8	int:SIRT6
Cytoband	6q22	MAN1A1 CEP85L	4.52e-05	8	59	2	6q22
Cytoband	11q22.3	CWF19L2 ELMOD1	1.48e-03	44	59	2	11q22.3
Cytoband	3p21.3	RBM5 LARS2	2.65e-03	59	59	2	3p21.3
GeneFamily	AAA ATPases	IQCA1 VPS4A	3.71e-03	53	31	2	413
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF2 VAV3	5.70e-03	66	31	2	722
GeneFamily	SH2 domain containing	VAV3 SH2D4B	1.29e-02	101	31	2	741
Coexpression	SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN	MAP9 CLGN SLC4A8 VAV3 ITPR1	8.93e-07	82	56	5	M244
Coexpression	FORTSCHEGGER_PHF8_TARGETS_UP	MAN1A1 NQO1 CENPV HMGB2 VAV3 ECE1 ITPR1	2.08e-06	278	56	7	M2487
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_UP	SLC4A7 CALR TEX2 EIF2AK3 ZC3HAV1	3.53e-05	174	56	5	M8947
Coexpression	GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP	P4HA2 MAN1A1 SYNE2 IDE EIF2AK3	5.65e-05	192	56	5	M3176
Coexpression	GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP	ABCC1 P4HA2 TAF1A LPIN2 RBM5	6.53e-05	198	56	5	M8407
Coexpression	GSE4142_PLASMA_CELL_VS_GC_BCELL_DN	CALR SYNE2 NQO1 UQCC2 ECE1	6.85e-05	200	56	5	M6385
Coexpression	KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN	DOCK5 PTPN13 LPIN2 HMGB2 IDE	6.85e-05	200	56	5	M3017
Coexpression	XU_GH1_EXOGENOUS_TARGETS_DN	ERCC4 SLC4A7 RASGRF2 HMGB2	7.61e-05	105	56	4	M17387
Coexpression	HALLMARK_UNFOLDED_PROTEIN_RESPONSE	HSP90B1 CALR EIF4G1 EIF2AK3	1.01e-04	113	56	4	M5922
Coexpression	SMID_BREAST_CANCER_BASAL_DN	MAP9 CLGN SLC4A7 MAN1A1 SLC4A8 NQO1 VAV3 ITPR1	1.13e-04	699	56	8	M4960
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	CASP8AP2 CWF19L2 SLC4A7 SLC4A8 SYNE2 CHD8 LARS2	1.45e-05	298	57	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_100	EIF4G1 RBM5 CHD8	2.72e-05	22	57	3	gudmap_developingGonad_e16.5_epididymis_100_k3
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	SYNE2 EIF4G1 RBM5 CHD8	2.80e-05	65	57	4	gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000	HSP90B1 ERCC4 RASGRF2 ANKRD11 RBM5 VAV3 IDE	3.31e-05	339	57	7	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_200	SYNE2 RBM5 CHD8	4.56e-05	26	57	3	gudmap_developingGonad_e18.5_ovary_200_k3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500	SYNE2 EIF4G1 ANKRD11 RBM5 CHD8	5.12e-05	150	57	5	gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	SOX5 CASP8AP2 CWF19L2 SLC4A7 SLC4A8 MMEL1 SYNE2 HMGB2 LARS2 SH2D4B ELMOD1	1.01e-04	1060	57	11	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_500	SYNE2 EIF4G1 RBM5 CHD8	1.57e-04	101	57	4	gudmap_developingGonad_e14.5_ ovary_500_k1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	CASP8AP2 CWF19L2 SLC4A7 SLC4A8 SYNE2	1.64e-04	192	57	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	SOX5 IQCA1 SYNE2 EIF4G1 ANKRD11 RBM5 CHD8 ECE1 ZC3HAV1	2.11e-04	778	57	9	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000	SYNE2 EIF4G1 ANKRD11 RBM5 CHD8	2.49e-04	210	57	5	gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000	HSP90B1 ERCC4 RASGRF2 ANKRD11 RBM5 HMGB2 UQCC2 VAV3 IDE	2.62e-04	801	57	9	gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	SOX5 CASP8AP2 CWF19L2 PTPN13 SLC4A7 SLC4A8 SYNE2 LPIN2 CHD8 LARS2	2.63e-04	986	57	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	SOX5 SLC4A7 SYNE2 EIF4G1 ANKRD11 RBM5 CHD8 ECE1 ZC3HAV1	2.74e-04	806	57	9	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	SYNE2 EIF4G1 ANKRD11 RBM5 CHD8	3.78e-04	230	57	5	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	kidney_P2_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_200	DOCK5 LPIN2	5.42e-04	13	57	2	gudmap_kidney_P2_CapMes_Crym_k1_200
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_200	DOCK5 LPIN2	5.42e-04	13	57	2	gudmap_kidney_P1_CapMes_Crym_k1_200
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_200	CENPV ZC3HAV1	5.42e-04	13	57	2	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k4_200
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3	SOX5 CASP8AP2 CWF19L2 SLC4A8 SYNE2 LPIN2 CENPV CHD8 LARS2	5.79e-04	893	57	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_200	EIF4G1 RBM5 CHD8	5.91e-04	61	57	3	gudmap_developingGonad_e12.5_epididymis_k2_200
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000	SLC4A7 SYNE2 EIF4G1 ANKRD11 RBM5	6.48e-04	259	57	5	gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#2_top-relative-expression-ranked_200	EIF4G1 RBM5 CHD8	7.12e-04	65	57	3	gudmap_developingGonad_e12.5_ovary_k2_200
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500	SYNE2 EIF4G1 ANKRD11 RBM5 CHD8 ZC3HAV1	7.22e-04	403	57	6	gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000	SYNE2 EIF4G1 RBM5 CHD8	7.24e-04	151	57	4	gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlas	Myeloid Cells, DC.8+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2	DOCK5 SLC4A7 SLC4A8 CENPV ECE1 ITPR1	8.10e-04	412	57	6	GSM538260_500
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_200	SYNE2 EIF4G1 RBM5 CHD8	8.38e-04	157	57	4	gudmap_developingGonad_P2_epididymis_200
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	SYNE2 EIF4G1 ANKRD11 RBM5 CHD8	8.49e-04	275	57	5	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	facebase_RNAseq_e8.5_FloorPlate_2500_K3	DOCK5 SOX5 CASP8AP2 CWF19L2 HSP90B1 PTPN13 SLC4A7 MMEL1 HMGB2 IDE LARS2	9.18e-04	1371	57	11	facebase_RNAseq_e8.5_FloorPlate_2500_K3
ToppCell	PSB\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP9 P4HA2 SLC4A8 IQCA1 CFAP58 CC2D2A FYB2	8.08e-09	198	59	7	4e6b0d1abc55d7a0d89bd7ecf0f13dc5bed66626
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CEP85L SYNE2 ANKRD11 EIF2AK3 ITPR1 ZC3HAV1	1.84e-07	188	59	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCC1 SLC4A7 RASGRF2 CEP85L SYNE2 ZC3HAV1	1.90e-07	189	59	6	df30478b288084a1bd48f660409dcc784040897c
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	ABCC1 PTPN13 SLC4A7 LPIN2 HMGB2 ZC3HAV1	2.35e-07	196	59	6	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	ABCC1 PTPN13 SLC4A7 LPIN2 HMGB2 ZC3HAV1	2.35e-07	196	59	6	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPIN2 NQO1 VAV3 IDE LARS2	3.65e-06	176	59	5	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 CEP85L SYNE2 ANKRD11 ZC3HAV1	3.86e-06	178	59	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	ILEUM-inflamed-(1)_CD8_Trm\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SLC4A7 SYNE2 LPIN2 HMGB2 ZC3HAV1	4.91e-06	187	59	5	a77d7ae44f47410bd92fb3aa0f44dce891752b63
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ABCC1 SLC4A8 VAV3 LEPR ITPR1	4.91e-06	187	59	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	SLC4A7 RASGRF2 CEP85L SYNE2 ZC3HAV1	5.30e-06	190	59	5	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 SLC4A7 MAN1A1 FYB2	5.44e-06	191	59	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	ASK428-Epithelial-Ciliated\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FMO3 IQCA1 NQO1 CFAP58 FYB2	5.44e-06	191	59	5	0c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC4A7 RASGRF2 CEP85L SYNE2 ZC3HAV1	5.87e-06	194	59	5	3d6f2d190dd50804afea299957cc44c2bb756134
ToppCell	B_cells-Plasma_cells_and_plasmablasts\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	HSP90B1 MAN1A1 CALR ZNF215 EIF2AK3	6.32e-06	197	59	5	3b1c574b3d119b63967bb1306f0353ecc4c522f3
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX4I1 LPIN2 NQO1 LARS2	7.27e-05	168	59	4	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	CEP85L SYNE2 VAV3 ZC3HAV1	7.44e-05	169	59	4	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 MAN1A1 IQCA1 FYB2	7.61e-05	170	59	4	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	PTPN13 SLC4A7 SYNE2 ZC3HAV1	7.79e-05	171	59	4	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE2 LPIN2 VAV3 LARS2	8.15e-05	173	59	4	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE2 LPIN2 VAV3 LARS2	8.15e-05	173	59	4	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	Control-B_cells-Plasma_cells\|Control / group, cell type (main and fine annotations)	HSP90B1 MAN1A1 ZNF215 EIF2AK3	8.52e-05	175	59	4	fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ABCC1 CWF19L2 CENPV UQCC2	8.52e-05	175	59	4	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MMEL1 ECE1 LEPR	8.71e-05	176	59	4	1df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCell	BAL-Mild-cDC_3\|Mild / Compartment, Disease Groups and Clusters	DOCK5 MAP9 SLC4A7 IDE	8.71e-05	176	59	4	f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 MMEL1 CFAP58 ELMOD1	9.10e-05	178	59	4	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 CALR EIF4G1 VAV3	9.10e-05	178	59	4	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 MMEL1 CFAP58 ELMOD1	9.10e-05	178	59	4	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 MMEL1 CFAP58 ELMOD1	9.10e-05	178	59	4	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	droplet-Marrow-nan-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSP90B1 TEX2 FYB2 ITPR1	9.29e-05	179	59	4	dcaf2191134a586d50ebaf67dcf5b815b54a722b
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSP90B1 TEX2 FYB2 ITPR1	9.29e-05	179	59	4	87a69f9f83b8f0c028a4874acb238f2e079bf51f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 MAN1A1 FYB2	9.70e-05	181	59	4	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	COPD-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	HSP90B1 MAN1A1 ZNF215 EIF2AK3	9.91e-05	182	59	4	19db653fe04c5e2957eea1f4893b1c1fca4ddcbd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 MAN1A1 FYB2	1.01e-04	183	59	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	COVID-19-B_cells-Plasma_cells\|COVID-19 / group, cell type (main and fine annotations)	HSP90B1 MAN1A1 ZNF215 EIF2AK3	1.01e-04	183	59	4	130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCell	COVID-19-B_cells\|COVID-19 / group, cell type (main and fine annotations)	HSP90B1 MAN1A1 ZNF215 EIF2AK3	1.01e-04	183	59	4	2c016bb59f131a0e821853b085289a3583f0a729
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NQO1 CDYL2 ECE1 LEPR	1.01e-04	183	59	4	3e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|lung / Disease (COVID-19 only), tissue and cell type	HSP90B1 MAN1A1 ZNF215 EIF2AK3	1.03e-04	184	59	4	480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HSP90B1 MAN1A1 ZNF215 EIF2AK3	1.06e-04	185	59	4	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	ILEUM-non-inflamed-(5)_IgG_plasma_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HSP90B1 TXLNB ZNF215 EIF2AK3	1.06e-04	185	59	4	93b9a47357152ea95dfdfe8e7d111906a4adc551
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK5 MAN1A1 VAV3 ELMOD1	1.06e-04	185	59	4	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSP90B1 SLC4A7 RASGRF2 EIF2AK3	1.06e-04	185	59	4	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE2 ANKRD11 HMGB2 LARS2	1.08e-04	186	59	4	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	HSP90B1 MAN1A1 TXLNB EIF2AK3	1.08e-04	186	59	4	e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK5 MAN1A1 VAV3 ELMOD1	1.08e-04	186	59	4	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE2 ANKRD11 HMGB2 LARS2	1.08e-04	186	59	4	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	B_cells-Plasma_cells_and_plasmablasts\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MAN1A1 TXLNB ZNF215 EIF2AK3	1.10e-04	187	59	4	9325cadd5f2c667d526696899e7aa36a98226d4b
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	SLC4A7 CEP85L SYNE2 ZC3HAV1	1.10e-04	187	59	4	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSP90B1 MAN1A1 ZNF215 EIF2AK3	1.12e-04	188	59	4	599195338070ac6b79bd114609d9e10cac4f1df4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 MAN1A1 FYB2	1.12e-04	188	59	4	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	Control-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	DOCK5 ANKRD11 HMGB2 ECE1	1.12e-04	188	59	4	47126c371a242c937499fd278a74a882df8f759c
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NQO1 HMGB2 IDE SSRP1	1.15e-04	189	59	4	45b9d00a4968fb22207d95228cdcf022afe1e50b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 MAN1A1 FYB2	1.15e-04	189	59	4	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.15e-04	189	59	4	b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRF2 CEP85L SYNE2 ZC3HAV1	1.15e-04	189	59	4	9ab77c6fcb573854da5922412f53d2168bda6b58
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAP9 MAN1A1 EIF2AK3 ITPR1	1.15e-04	189	59	4	b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NQO1 HMGB2 IDE SSRP1	1.15e-04	189	59	4	8382d331e01e83591ba9c8ea83edbf2436c18b17
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRF2 CEP85L SYNE2 ZC3HAV1	1.15e-04	189	59	4	5a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCell	Epithelial-D_(Ciliated)\|World / shred on cell class and cell subclass (v4)	MAP9 IQCA1 CFAP58 ELMOD1	1.15e-04	189	59	4	0bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 MAN1A1 FYB2	1.15e-04	189	59	4	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PTPN13 FYB2 ZC3HAV1	1.15e-04	189	59	4	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.15e-04	189	59	4	4e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell	IPF-Lymphoid-T\|IPF / Disease state, Lineage and Cell class	ABCC1 SLC4A7 SYNE2 ZC3HAV1	1.17e-04	190	59	4	d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 MAN1A1 ZNF215 EIF2AK3	1.17e-04	190	59	4	84eb7761f537d270673909a71d4f122e826769d5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 MAN1A1 IQCA1 FYB2	1.17e-04	190	59	4	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	P4HA2 SH2D4B ITPR1 ZC3HAV1	1.19e-04	191	59	4	40813c397f533c2f4a6359a77757f736b6d9e07d
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.19e-04	191	59	4	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	Adult-Immune-T_lymphocyte-D175\|Adult / Lineage, Cell type, age group and donor	RASGRF2 CEP85L SYNE2 ZC3HAV1	1.19e-04	191	59	4	0b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.19e-04	191	59	4	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 MAN1A1 CALR ZNF215	1.19e-04	191	59	4	dd1d38a531a272a746c16807688013d29cab823a
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	RASGRF2 CEP85L SYNE2 ZC3HAV1	1.19e-04	191	59	4	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.19e-04	191	59	4	96483adb97c81208aa513782550acd8a08b63866
ToppCell	remission-Plasmablast\|remission / disease stage, cell group and cell class	HSP90B1 MAN1A1 CALR ZNF215	1.22e-04	192	59	4	4bcf22061905177ad8625b87be2fbca9bff03ec6
ToppCell	COPD-Lymphoid-T\|World / Disease state, Lineage and Cell class	ABCC1 SLC4A7 SYNE2 ZC3HAV1	1.22e-04	192	59	4	eb4909574fb5fc91399463523e2737095773200a
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MAN1A1 LPIN2 ITPR1	1.22e-04	192	59	4	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	SOX5 PTPN13 FYB2 ITPR1	1.22e-04	192	59	4	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 IQCA1 FYB2 ZC3HAV1	1.22e-04	192	59	4	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.22e-04	192	59	4	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSP90B1 CALR EIF4G1 ECE1	1.22e-04	192	59	4	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	SOX5 PTPN13 SLC4A7 ITPR1	1.22e-04	192	59	4	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	IPF-Lymphoid-T\|World / Disease state, Lineage and Cell class	ABCC1 SLC4A7 SYNE2 ZC3HAV1	1.22e-04	192	59	4	b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 IQCA1 FYB2 ZC3HAV1	1.22e-04	192	59	4	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	PND03-Epithelial-Epithelial_Airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP9 IQCA1 CFAP58 ELMOD1	1.22e-04	192	59	4	2d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	902dea0bf6c2997d8b877ae01113460e511a364a
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	239f2ac64f63d4d65997ba83b932a1fab1909efb
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	2790b245d6052063c207087b91fb9375a0e8055d
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	RASGRF2 VAV3 ECE1 LEPR	1.24e-04	193	59	4	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	38bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCell	remission-Plasmablast\|World / disease stage, cell group and cell class	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	d62617c72863642f2222f7ed28bc6b90ee09b4e0
ToppCell	Control-Lymphoid-T\|Control / Disease state, Lineage and Cell class	ABCC1 SLC4A7 SYNE2 ZC3HAV1	1.24e-04	193	59	4	af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	3ba6d44248690b80f4caf791d463e60f1ab816c4
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	94daa8a5d23558998fe3bff585344e22ce679f2d
ToppCell	Adult-Immune-T_lymphocyte\|Adult / Lineage, Cell type, age group and donor	RASGRF2 CEP85L SYNE2 ZC3HAV1	1.24e-04	193	59	4	26df0c4c8a2355dd5503fadd07e368eb9a2bf06a
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	33dad901e0597f0057edc2bfbd64fd81f298b94e
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	RASGRF2 SYNE2 VAV3 LEPR	1.24e-04	193	59	4	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	nucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCC1 SLC4A7 SYNE2 ZC3HAV1	1.24e-04	193	59	4	9c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ToppCell	facs-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSP90B1 CALR UQCC2 ECE1	1.24e-04	193	59	4	15c86e20b97b6983410b36d308cddff56d141c98
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC4A7 CEP85L SYNE2 ZC3HAV1	1.24e-04	193	59	4	b9769b45125d2244afe53f9f71c92c04ddccf980
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 MAN1A1 CALR ZNF215	1.24e-04	193	59	4	8f57b0473a2c2c07f83e5fe70f16862b1bb3b514
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	MAP9 P4HA2 HSP90B1 RBM5 EIF2AK3 LEPR ITPR1	3.68e-07	180	58	7	947_UP
Drug	mefloquina	ABCC1 HSP90B1 CALR EIF2AK3	1.13e-06	31	58	4	CID000004046
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	P4HA2 HSP90B1 CALR RBM5 EIF2AK3 ZC3HAV1	5.50e-06	175	58	6	1006_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	P4HA2 HSP90B1 CALR EIF2AK3 LEPR ZC3HAV1	5.87e-06	177	58	6	6943_UP
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	P4HA2 SLC4A8 RBM5 LARS2 LEPR ZC3HAV1	8.81e-06	190	58	6	999_UP
Drug	Buthionine Sulfoximine	ABCC1 FMO3 CALR COX4I1 NQO1 HMGB2 EIF2AK3	1.24e-05	306	58	7	ctd:D019328
Drug	Chloroprene	DOCK5 CASP8AP2 ABCC1 CWF19L2 FMO3 EIF4G1 LPIN2 NQO1 ANKRD11 RBM5 VAV3 DDHD2 ELMOD1	2.68e-05	1348	58	13	ctd:D002737
Disease	chronic kidney disease (implicated_via_orthology)	NQO1 LEPR	2.56e-04	12	59	2	DOID:784 (implicated_via_orthology)
Disease	chronic obstructive pulmonary disease (is_implicated_in)	ABCC1 NQO1 LEPR	2.77e-04	63	59	3	DOID:3083 (is_implicated_in)
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A8	4.06e-04	15	59	2	DOID:2355 (implicated_via_orthology)
Disease	colorectal mucinous adenocarcinoma	SOX5 RASGRF2	4.63e-04	16	59	2	EFO_0009361
Disease	Hypertensive disease	ABCC1 VAV3 ECE1 LEPR	5.75e-04	190	59	4	C0020538
Disease	autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease	MMEL1 VAV3	5.89e-04	18	59	2	EFO_0003779, EFO_0004237, EFO_0006812
Disease	Autism Spectrum Disorders	SOX5 ANKRD11 CHD8	6.68e-04	85	59	3	C1510586
Disease	response to anticonvulsant	ABCC1 VAV3 LEPR	6.68e-04	85	59	3	GO_0036277
Disease	alcohol consumption measurement	SOX5 ERCC4 SLC4A8 MMEL1 RASGRF2 EIF4G1 NQO1 ANKRD11 IP6K2	7.60e-04	1242	59	9	EFO_0007878
Disease	chronic obstructive pulmonary disease (is_marker_for)	ABCC1 NQO1 LEPR	9.80e-04	97	59	3	DOID:3083 (is_marker_for)
Disease	Prostatic Neoplasms	HSP90B1 CALR NQO1 HMGB2 VAV3 ITPR1	1.42e-03	616	59	6	C0033578
Disease	Malignant neoplasm of prostate	HSP90B1 CALR NQO1 HMGB2 VAV3 ITPR1	1.42e-03	616	59	6	C0376358
Disease	Hyperglycemia, Postprandial	NQO1 LEPR	1.65e-03	30	59	2	C1855520
Disease	Hyperglycemia	NQO1 LEPR	1.65e-03	30	59	2	C0020456
Disease	conduct disorder	ERCC4 CC2D2A	1.76e-03	31	59	2	EFO_0004216
Disease	fear of minor pain measurement	DOCK5 IQCA1	1.76e-03	31	59	2	EFO_0008340
Disease	hypertension (is_implicated_in)	FMO3 ECE1 LEPR	1.85e-03	121	59	3	DOID:10763 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KWAKKADLDMDLLNS	CHD8	1376	Q9HCK8
SKFSKAEWEKKRMDK	ELMOD1	216	Q8N336
SKMKLEEKEWLFKDE	ANKRD11	701	Q6UB99
KVSVADWKVMAFSKK	EIF2AK3	311	Q9NZJ5
DMKKKLWKFVDDQLD	CASP8AP2	1126	Q9UKL3
KNKEEDEKWKMSPSL	IQCA1	376	Q86XH1
AMATKDKIDKWDLIK	nan	1001	O00370
EKMEKKRKWFGKSET	FMO3	411	P31513
KKKLMKEVDTGWAKA	LEXM	81	Q3ZCV2
ASFEAWKAMKEKEAK	MAP9	471	Q49MG5
EALQAFEKWKEKKME	MAP9	511	Q49MG5
MKSHKLEEEFEWLKK	IP6K2	141	Q9UHH9
KSVFHWDMKSKDKEG	NRAP	96	Q86VF7
VLFMKWSDNKDDILK	ITPR1	221	Q14643
SERWKTMSAKEKSKF	HMGB2	46	P26583
TIASLKKEIEKAWKM	CFAP58	91	Q5T655
WSMNKKLIDLSSKDI	CWF19L2	796	Q2TBE0
MLAVTLDEWKKKLES	DDHD2	141	O94830
GDTMKKEKNVTLLWK	LEPR	651	P48357
LGWMDEESKKKAQEK	MMEL1	486	Q495T6
SEEEKLADWKKMACL	RBM5	636	P52756
AMKEAAAAALKKKGW	NQO1	21	P15559
EEAKLSKIKSWANKM	P4HA2	51	O15460
EPLLNWMKDKALKDK	HSP90B1	616	P14625
WMKDKALKDKIEKAV	HSP90B1	621	P14625
DSMLTWEKEELKSMK	CCDC105	196	Q8IYK2
TDMKKLAKWAAESKL	CC2D2A	846	Q9P2K1
GKMWEKAIKLSKELA	DOCK5	1311	Q9H7D0
TWGVTKAAEKQMKDK	CALR	346	P27797
GSDWEKAMKEHKTIK	CENPV	256	Q7Z7K6
DFSKWESMLKIKEGL	CEP85L	356	Q5SZL2
MTEDIKLNKAEKAWK	EIF4G1	721	Q04637
KAWLMSDKTDLEAKK	MAN1A1	421	P33908
IKDTAMSKLWFKQDD	IDE	551	P14735
IKKAFEESLSTLKWM	ECE1	471	P42892
ALKEKEKASWSSLSM	COX4I1	61	P13073
DVLSKKKIWASSMDL	PTPN13	291	Q12923
KMTKILCKWKKADLT	PGBD3	106	Q8N328
KAEAKKEETWKLMEA	ABCC1	936	P33527
KEFEGNMTWKIKLKS	TAS2R43	156	P59537
SDPKLVAKWKDMKTN	TSEN2	81	Q8NCE0
LSWLDDLMPESKKKK	SLC4A7	1131	Q9Y6M7
ALSDKKGDLLKAMTW	SYNE2	4581	Q8WXH0
HAKTKEKLEVTWEKM	LARS2	626	Q15031
EKLEVTWEKMSKSKH	LARS2	631	Q15031
TWAKVSKQTKALMDK	RASGRF2	1111	O14827
WSEKKMELSKLDKDD	TAF1A	191	Q15573
ESKDEDKLKMWKPKF	FYB2	596	Q5VWT5
LSWLDDLMPESKKKK	SLC4A8	1001	Q2Y0W8
KGMSKEKKEEWDRKA	SSRP1	586	Q08945
EKECLMLKQLWSSSK	CDYL2	476	Q8N8U2
LAGWVLSKAKKDDMD	CLGN	71	O14967
LSEHKSTKDWKMAPK	ZNF75CP	181	Q92670
TLEELKEIDKGMWKK	UQCC2	96	Q9BRT2
SSDGFIKMWKLKQDK	PAK1IP1	266	Q9NWT1
LKLESKKKRWIMEKE	ZNF215	216	Q9UL58
KWKVEMEDRKAAKVL	SH2D4B	141	Q5SQS7
EKLLSKDWKDKLLAM	SOX5	166	P35711
ELLDKFTWKKSQMKE	ZC3HAV1	766	Q7Z2W4
FTWKKSQMKEEGKLL	ZC3HAV1	771	Q7Z2W4
EKDSKAEEVWMKFRK	ERCC4	441	Q92889
TTKKMKKLEKDTATW	TXLNB	391	Q8N3L3
WSDLVSKKIQMKLSK	TEX2	841	Q8IWB9
DLMSKWLGESEKLVK	VPS4A	196	Q9UN37
TKDLKKKWLEQFEMA	VAV3	486	Q9UKW4
ATVESWVKDKMPKKS	LPIN2	541	Q92539