| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | ATP:ADP antiporter activity | 4.11e-07 | 5 | 70 | 3 | GO:0005471 | |
| GeneOntologyMolecularFunction | ADP transmembrane transporter activity | 6.67e-06 | 11 | 70 | 3 | GO:0015217 | |
| GeneOntologyMolecularFunction | ATP transmembrane transporter activity | 1.46e-05 | 14 | 70 | 3 | GO:0005347 | |
| GeneOntologyMolecularFunction | purine ribonucleotide transmembrane transporter activity | 6.95e-05 | 23 | 70 | 3 | GO:0005346 | |
| GeneOntologyMolecularFunction | adenine nucleotide transmembrane transporter activity | 1.01e-04 | 26 | 70 | 3 | GO:0000295 | |
| GeneOntologyMolecularFunction | oxidative phosphorylation uncoupler activity | 1.20e-04 | 5 | 70 | 2 | GO:0017077 | |
| GeneOntologyMolecularFunction | adenine transmembrane transporter activity | 1.20e-04 | 5 | 70 | 2 | GO:0015207 | |
| GeneOntologyMolecularFunction | purine nucleotide transmembrane transporter activity | 1.41e-04 | 29 | 70 | 3 | GO:0015216 | |
| GeneOntologyMolecularFunction | nucleotide transmembrane transporter activity | 2.09e-04 | 33 | 70 | 3 | GO:0015215 | |
| GeneOntologyMolecularFunction | sterol ester esterase activity | 2.52e-04 | 7 | 70 | 2 | GO:0004771 | |
| GeneOntologyMolecularFunction | ATP-dependent chromatin remodeler activity | 2.94e-04 | 37 | 70 | 3 | GO:0140658 | |
| GeneOntologyMolecularFunction | organophosphate ester transmembrane transporter activity | 3.44e-04 | 39 | 70 | 3 | GO:0015605 | |
| GeneOntologyMolecularFunction | purine nucleobase transmembrane transporter activity | 5.35e-04 | 10 | 70 | 2 | GO:0005345 | |
| GeneOntologyMolecularFunction | nucleobase transmembrane transporter activity | 6.53e-04 | 11 | 70 | 2 | GO:0015205 | |
| GeneOntologyMolecularFunction | serine hydrolase activity | 8.90e-04 | 212 | 70 | 5 | GO:0017171 | |
| GeneOntologyMolecularFunction | carbohydrate derivative transmembrane transporter activity | 1.17e-03 | 59 | 70 | 3 | GO:1901505 | |
| GeneOntologyMolecularFunction | nucleobase-containing compound transmembrane transporter activity | 1.17e-03 | 59 | 70 | 3 | GO:0015932 | |
| GeneOntologyMolecularFunction | neurexin family protein binding | 1.41e-03 | 16 | 70 | 2 | GO:0042043 | |
| GeneOntologyMolecularFunction | intramolecular oxidoreductase activity, transposing C=C bonds | 1.99e-03 | 19 | 70 | 2 | GO:0016863 | |
| GeneOntologyMolecularFunction | carbohydrate kinase activity | 2.44e-03 | 21 | 70 | 2 | GO:0019200 | |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SEC61A2 CNNM3 ABCB10 SLC25A4 SLC25A5 SLC25A6 SLC16A14 SLC38A7 OCA2 SEC61A1 SLC39A7 | 2.55e-03 | 1180 | 70 | 11 | GO:0022857 |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | 3.66e-03 | 293 | 70 | 5 | GO:0008514 | |
| GeneOntologyMolecularFunction | secondary active transmembrane transporter activity | 3.82e-03 | 296 | 70 | 5 | GO:0015291 | |
| GeneOntologyMolecularFunction | protein transmembrane transporter activity | 4.32e-03 | 28 | 70 | 2 | GO:0008320 | |
| GeneOntologyMolecularFunction | cell adhesion molecule binding | 4.94e-03 | 599 | 70 | 7 | GO:0050839 | |
| GeneOntologyMolecularFunction | transporter activity | SEC61A2 CNNM3 ABCB10 SLC25A4 SLC25A5 SLC25A6 SLC16A14 SLC38A7 OCA2 SEC61A1 SLC39A7 | 5.00e-03 | 1289 | 70 | 11 | GO:0005215 |
| GeneOntologyBiologicalProcess | mitochondrial ADP transmembrane transport | 3.41e-07 | 5 | 68 | 3 | GO:0140021 | |
| GeneOntologyBiologicalProcess | ATP transport | 9.12e-07 | 23 | 68 | 4 | GO:0015867 | |
| GeneOntologyBiologicalProcess | mitochondrial ATP transmembrane transport | 1.90e-06 | 8 | 68 | 3 | GO:1990544 | |
| GeneOntologyBiologicalProcess | ADP transport | 7.38e-06 | 12 | 68 | 3 | GO:0015866 | |
| GeneOntologyBiologicalProcess | purine ribonucleotide transport | 9.03e-06 | 40 | 68 | 4 | GO:0015868 | |
| GeneOntologyBiologicalProcess | adenine nucleotide transport | 1.10e-05 | 42 | 68 | 4 | GO:0051503 | |
| GeneOntologyBiologicalProcess | purine nucleotide transport | 1.33e-05 | 44 | 68 | 4 | GO:0015865 | |
| GeneOntologyBiologicalProcess | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 1.52e-05 | 15 | 68 | 3 | GO:1901029 | |
| GeneOntologyBiologicalProcess | regulation of mitochondrion organization | 1.57e-05 | 162 | 68 | 6 | GO:0010821 | |
| GeneOntologyBiologicalProcess | nucleotide transport | 2.22e-05 | 50 | 68 | 4 | GO:0006862 | |
| GeneOntologyBiologicalProcess | negative regulation of mitochondrial membrane permeability | 5.79e-05 | 23 | 68 | 3 | GO:0035795 | |
| GeneOntologyBiologicalProcess | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 6.60e-05 | 24 | 68 | 3 | GO:1901028 | |
| GeneOntologyBiologicalProcess | negative regulation of membrane permeability | 8.44e-05 | 26 | 68 | 3 | GO:1905709 | |
| GeneOntologyBiologicalProcess | nucleotide transmembrane transport | 1.44e-04 | 31 | 68 | 3 | GO:1901679 | |
| GeneOntologyBiologicalProcess | adenine transport | 1.59e-04 | 6 | 68 | 2 | GO:0015853 | |
| GeneOntologyBiologicalProcess | mitochondrial outer membrane permeabilization | 1.74e-04 | 33 | 68 | 3 | GO:0097345 | |
| GeneOntologyBiologicalProcess | regulation of mitophagy | 2.66e-04 | 38 | 68 | 3 | GO:1901524 | |
| GeneOntologyBiologicalProcess | carbohydrate derivative transport | 2.86e-04 | 96 | 68 | 4 | GO:1901264 | |
| GeneOntologyBiologicalProcess | SRP-dependent cotranslational protein targeting to membrane, translocation | 2.96e-04 | 8 | 68 | 2 | GO:0006616 | |
| GeneOntologyBiologicalProcess | post-translational protein targeting to membrane, translocation | 2.96e-04 | 8 | 68 | 2 | GO:0031204 | |
| GeneOntologyBiologicalProcess | purine-containing compound transmembrane transport | 3.10e-04 | 40 | 68 | 3 | GO:0072530 | |
| GeneOntologyBiologicalProcess | positive regulation of mitochondrial membrane permeability involved in apoptotic process | 3.10e-04 | 40 | 68 | 3 | GO:1902110 | |
| GeneOntologyBiologicalProcess | mitochondrial outer membrane permeabilization involved in programmed cell death | 3.59e-04 | 42 | 68 | 3 | GO:1902686 | |
| GeneOntologyBiologicalProcess | positive regulation of mitochondrial membrane permeability | 4.40e-04 | 45 | 68 | 3 | GO:0035794 | |
| GeneOntologyBiologicalProcess | regulation of autophagy of mitochondrion | 4.40e-04 | 45 | 68 | 3 | GO:1903146 | |
| GeneOntologyBiologicalProcess | regulation of mitochondrial membrane permeability involved in apoptotic process | 5.66e-04 | 49 | 68 | 3 | GO:1902108 | |
| GeneOntologyBiologicalProcess | regulation of synapse pruning | 5.78e-04 | 11 | 68 | 2 | GO:1905806 | |
| GeneOntologyBiologicalProcess | positive regulation of membrane permeability | 6.01e-04 | 50 | 68 | 3 | GO:1905710 | |
| GeneOntologyBiologicalProcess | purine nucleobase transport | 6.92e-04 | 12 | 68 | 2 | GO:0006863 | |
| GeneOntologyBiologicalProcess | pentose metabolic process | 8.16e-04 | 13 | 68 | 2 | GO:0019321 | |
| GeneOntologyBiologicalProcess | cellular response to interleukin-12 | 8.16e-04 | 13 | 68 | 2 | GO:0071349 | |
| GeneOntologyBiologicalProcess | nucleobase transport | 8.16e-04 | 13 | 68 | 2 | GO:0015851 | |
| GeneOntologyCellularComponent | Sec61 translocon complex | 1.13e-04 | 5 | 71 | 2 | GO:0005784 | |
| GeneOntologyCellularComponent | translocon complex | 1.69e-04 | 6 | 71 | 2 | GO:0071256 | |
| GeneOntologyCellularComponent | mitochondrial permeability transition pore complex | 2.36e-04 | 7 | 71 | 2 | GO:0005757 | |
| Domain | Mit_uncoupling | 9.92e-06 | 12 | 68 | 3 | IPR002030 | |
| Domain | Plug_translocon | 1.31e-05 | 2 | 68 | 2 | PF10559 | |
| Domain | SecY_su_dom | 1.31e-05 | 2 | 68 | 2 | IPR023201 | |
| Domain | SecY | 1.31e-05 | 2 | 68 | 2 | PF00344 | |
| Domain | SECY_1 | 1.31e-05 | 2 | 68 | 2 | PS00755 | |
| Domain | SECY_2 | 1.31e-05 | 2 | 68 | 2 | PS00756 | |
| Domain | - | 1.31e-05 | 2 | 68 | 2 | 1.10.3370.10 | |
| Domain | Translocon_Sec61/SecY_plug_dom | 1.31e-05 | 2 | 68 | 2 | IPR019561 | |
| Domain | SecY_CS | 1.31e-05 | 2 | 68 | 2 | IPR030659 | |
| Domain | SecY/SEC61-alpha | 1.31e-05 | 2 | 68 | 2 | IPR002208 | |
| Domain | - | 7.30e-05 | 119 | 68 | 5 | 3.40.50.1820 | |
| Domain | AB_hydrolase | 7.30e-05 | 119 | 68 | 5 | IPR029058 | |
| Domain | Lipase_GDXG_put_SER_AS | 7.80e-05 | 4 | 68 | 2 | IPR033140 | |
| Domain | Lipase_GDXG_HIS_AS | 7.80e-05 | 4 | 68 | 2 | IPR002168 | |
| Domain | Carb_kinase_FGGY_C | 1.30e-04 | 5 | 68 | 2 | IPR018485 | |
| Domain | Aden_trnslctor | 1.42e-04 | 28 | 68 | 3 | IPR002113 | |
| Domain | BRK | 1.94e-04 | 6 | 68 | 2 | SM00592 | |
| Domain | FGGY_C | 1.94e-04 | 6 | 68 | 2 | PF02782 | |
| Domain | Carb_kinase_FGGY_N | 1.94e-04 | 6 | 68 | 2 | IPR018484 | |
| Domain | LIPASE_GDXG_SER | 1.94e-04 | 6 | 68 | 2 | PS01174 | |
| Domain | LIPASE_GDXG_HIS | 1.94e-04 | 6 | 68 | 2 | PS01173 | |
| Domain | BRK_domain | 1.94e-04 | 6 | 68 | 2 | IPR006576 | |
| Domain | BRK | 1.94e-04 | 6 | 68 | 2 | PF07533 | |
| Domain | SNF2_N | 2.12e-04 | 32 | 68 | 3 | IPR000330 | |
| Domain | SNF2_N | 2.12e-04 | 32 | 68 | 3 | PF00176 | |
| Domain | Mit_carrier | 2.12e-04 | 32 | 68 | 3 | IPR002067 | |
| Domain | Carb_kinase_FGGY | 2.71e-04 | 7 | 68 | 2 | IPR000577 | |
| Domain | AB_hydrolase_3 | 2.71e-04 | 7 | 68 | 2 | IPR013094 | |
| Domain | FGGY_N | 2.71e-04 | 7 | 68 | 2 | PF00370 | |
| Domain | Abhydrolase_3 | 2.71e-04 | 7 | 68 | 2 | PF07859 | |
| Domain | SOLCAR | 9.49e-04 | 53 | 68 | 3 | PS50920 | |
| Domain | - | 9.49e-04 | 53 | 68 | 3 | 1.50.40.10 | |
| Domain | Mitochondrial_sb/sol_carrier | 9.49e-04 | 53 | 68 | 3 | IPR018108 | |
| Domain | Mito_carr | 9.49e-04 | 53 | 68 | 3 | PF00153 | |
| Domain | Mt_carrier_dom | 9.49e-04 | 53 | 68 | 3 | IPR023395 | |
| Domain | Chromo_domain | 3.42e-03 | 24 | 68 | 2 | IPR023780 | |
| Domain | TIR_dom | 3.71e-03 | 25 | 68 | 2 | IPR000157 | |
| Domain | Chromo | 4.01e-03 | 26 | 68 | 2 | PF00385 | |
| Domain | CHROMO_1 | 4.64e-03 | 28 | 68 | 2 | PS00598 | |
| Domain | CHROMO_2 | 4.64e-03 | 28 | 68 | 2 | PS50013 | |
| Domain | Galactose-bd-like | 4.88e-03 | 94 | 68 | 3 | IPR008979 | |
| Domain | EGF_LAM_2 | 5.32e-03 | 30 | 68 | 2 | PS50027 | |
| Domain | EGF_LAM_1 | 5.32e-03 | 30 | 68 | 2 | PS01248 | |
| Domain | Chromodomain-like | 6.04e-03 | 32 | 68 | 2 | IPR016197 | |
| Domain | Chromo/shadow_dom | 6.41e-03 | 33 | 68 | 2 | IPR000953 | |
| Domain | CHROMO | 6.41e-03 | 33 | 68 | 2 | SM00298 | |
| Domain | Helicase_C | 6.99e-03 | 107 | 68 | 3 | PF00271 | |
| Domain | HELICc | 6.99e-03 | 107 | 68 | 3 | SM00490 | |
| Domain | Helicase_C | 7.18e-03 | 108 | 68 | 3 | IPR001650 | |
| Domain | Laminin_EGF | 7.19e-03 | 35 | 68 | 2 | PF00053 | |
| Domain | EGF_Lam | 7.19e-03 | 35 | 68 | 2 | SM00180 | |
| Domain | DNA/RNA_helicase_DEAH_CS | 7.19e-03 | 35 | 68 | 2 | IPR002464 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006 | 4.95e-06 | 10 | 50 | 3 | M47694 | |
| Pathway | REACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE | 9.03e-06 | 12 | 50 | 3 | M27728 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 1.17e-05 | 13 | 50 | 3 | M47696 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY | 1.17e-05 | 13 | 50 | 3 | M47751 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY | 1.17e-05 | 13 | 50 | 3 | M47703 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004 | 1.49e-05 | 14 | 50 | 3 | M47692 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM | 1.85e-05 | 15 | 50 | 3 | M47691 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 2.28e-05 | 16 | 50 | 3 | M47695 | |
| Pathway | KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM | 3.30e-05 | 18 | 50 | 3 | M47761 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 3.30e-05 | 18 | 50 | 3 | M47659 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM | 3.91e-05 | 19 | 50 | 3 | M47677 | |
| Pathway | KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 3.91e-05 | 19 | 50 | 3 | M47760 | |
| Pathway | KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY | 4.59e-05 | 20 | 50 | 3 | M47688 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY | 5.34e-05 | 21 | 50 | 3 | M47689 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 6.17e-05 | 22 | 50 | 3 | M47690 | |
| Pathway | KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY | 6.17e-05 | 22 | 50 | 3 | M47675 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY | 7.07e-05 | 23 | 50 | 3 | M47676 | |
| Pathway | KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY | 7.07e-05 | 23 | 50 | 3 | M47666 | |
| Pathway | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | 3.00e-04 | 37 | 50 | 3 | M1029 | |
| Pathway | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | 4.69e-04 | 43 | 50 | 3 | M881 | |
| Pathway | BIOCARTA_ETC_PATHWAY | 5.45e-04 | 10 | 50 | 2 | M15371 | |
| Pathway | REACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE | 6.64e-04 | 11 | 50 | 2 | MM15471 | |
| Pubmed | DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. | 8.51e-09 | 3 | 72 | 3 | 2541251 | |
| Pubmed | Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver. | 8.51e-09 | 3 | 72 | 3 | 2829183 | |
| Pubmed | 8.51e-09 | 3 | 72 | 3 | 12450408 | ||
| Pubmed | 3.40e-08 | 4 | 72 | 3 | 33396658 | ||
| Pubmed | 1.69e-07 | 6 | 72 | 3 | 10620603 | ||
| Pubmed | 2.96e-07 | 7 | 72 | 3 | 21370995 | ||
| Pubmed | 4.44e-07 | 73 | 72 | 5 | 23464991 | ||
| Pubmed | 4.73e-07 | 8 | 72 | 3 | 27641616 | ||
| Pubmed | CNNM3 ABCB10 SLC25A4 SLC25A5 SLC25A6 USO1 SREBF2 RCN2 RHBDD3 SEC61A1 PGAM5 SLC39A7 | 5.61e-07 | 952 | 72 | 12 | 38569033 | |
| Pubmed | 1.85e-06 | 12 | 72 | 3 | 16120388 | ||
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 20625037 | ||
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 27048932 | ||
| Pubmed | Role of adenine nucleotide translocator 1 in mtDNA maintenance. | 4.23e-06 | 2 | 72 | 2 | 10926541 | |
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 18480044 | ||
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 16556444 | ||
| Pubmed | Abrogation of neutral cholesterol ester hydrolytic activity causes adrenal enlargement. | 4.23e-06 | 2 | 72 | 2 | 21111707 | |
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 2823266 | ||
| Pubmed | Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages. | 4.23e-06 | 2 | 72 | 2 | 24891333 | |
| Pubmed | Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes. | 4.23e-06 | 2 | 72 | 2 | 10974536 | |
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 26842067 | ||
| Pubmed | 4.23e-06 | 2 | 72 | 2 | 12112115 | ||
| Pubmed | The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. | 4.23e-06 | 2 | 72 | 2 | 14749836 | |
| Pubmed | A novel missense adenine nucleotide translocator-1 gene mutation in a Greek adPEO family. | 4.23e-06 | 2 | 72 | 2 | 11756613 | |
| Pubmed | Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors. | 6.38e-06 | 125 | 72 | 5 | 36030824 | |
| Pubmed | 9.76e-06 | 64 | 72 | 4 | 22865885 | ||
| Pubmed | Identification of the Mitochondrial Heme Metabolism Complex. | 1.10e-05 | 21 | 72 | 3 | 26287972 | |
| Pubmed | 1.27e-05 | 3 | 72 | 2 | 28533432 | ||
| Pubmed | 1.27e-05 | 3 | 72 | 2 | 16831128 | ||
| Pubmed | Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. | 1.56e-05 | 256 | 72 | 6 | 24189400 | |
| Pubmed | Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease. | 1.67e-05 | 24 | 72 | 3 | 24725412 | |
| Pubmed | Rapid evolution of human pseudoautosomal genes and their mouse homologs. | 2.53e-05 | 4 | 72 | 2 | 8903724 | |
| Pubmed | Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis. | 2.53e-05 | 4 | 72 | 2 | 19723498 | |
| Pubmed | Human-Specific ARHGAP11B Acts in Mitochondria to Expand Neocortical Progenitors by Glutaminolysis. | 2.53e-05 | 4 | 72 | 2 | 31883789 | |
| Pubmed | 2.53e-05 | 4 | 72 | 2 | 22423112 | ||
| Pubmed | The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment. | 2.53e-05 | 4 | 72 | 2 | 10212142 | |
| Pubmed | Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. | 2.53e-05 | 4 | 72 | 2 | 31489369 | |
| Pubmed | The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. | 2.53e-05 | 4 | 72 | 2 | 31618756 | |
| Pubmed | 2.53e-05 | 4 | 72 | 2 | 11287411 | ||
| Pubmed | 4.21e-05 | 5 | 72 | 2 | 9565615 | ||
| Pubmed | H+ transport is an integral function of the mitochondrial ADP/ATP carrier. | 4.21e-05 | 5 | 72 | 2 | 31341297 | |
| Pubmed | A High-Density Human Mitochondrial Proximity Interaction Network. | SEC61A2 MRM3 PDSS2 ABCB10 SLC25A4 SLC25A5 SLC25A6 SARM1 CUL7 SEC61A1 PREPL PGAM5 | 5.39e-05 | 1496 | 72 | 12 | 32877691 |
| Pubmed | ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy. | 6.31e-05 | 6 | 72 | 2 | 37624892 | |
| Pubmed | 6.31e-05 | 6 | 72 | 2 | 16705175 | ||
| Pubmed | Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. | 6.31e-05 | 6 | 72 | 2 | 17715127 | |
| Pubmed | 7.20e-05 | 207 | 72 | 5 | 20186120 | ||
| Pubmed | RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes. | 8.09e-05 | 344 | 72 | 6 | 36282215 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | CCDC142 TNRC18 MFHAS1 LAMB2 CHD8 NLGN2 IL17RD TMEM127 SOWAHB ZNF503 | 9.04e-05 | 1105 | 72 | 10 | 35748872 |
| Pubmed | Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome. | 9.39e-05 | 219 | 72 | 5 | 31353912 | |
| Pubmed | Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. | MRM3 PDSS2 ABCB10 SLC25A4 SLC25A5 SLC25A6 SARM1 OVCA2 PREPL PGAM5 | 1.13e-04 | 1136 | 72 | 10 | 34800366 |
| Pubmed | Genotype-phenotype correlations in non-Finnish congenital nephrotic syndrome. | 1.17e-04 | 8 | 72 | 2 | 20507940 | |
| Pubmed | BRACHYURY directs histone acetylation to target loci during mesoderm development. | 1.17e-04 | 8 | 72 | 2 | 29141987 | |
| Pubmed | 1.33e-04 | 236 | 72 | 5 | 36339263 | ||
| Pubmed | 1.51e-04 | 9 | 72 | 2 | 27218139 | ||
| Pubmed | The mitochondrial transporter family SLC25: identification, properties and physiopathology. | 1.85e-04 | 53 | 72 | 3 | 23266187 | |
| Pubmed | Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. | 1.85e-04 | 573 | 72 | 7 | 28330616 | |
| Pubmed | Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. | MRM3 SLC25A4 SLC25A5 USO1 RCN2 LAMB2 NCEH1 CHD8 SEC61A1 PGAM5 SLC39A7 | 1.87e-04 | 1451 | 72 | 11 | 30550785 |
| Pubmed | Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75. | 1.88e-04 | 10 | 72 | 2 | 30590033 | |
| Pubmed | Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants. | 1.94e-04 | 256 | 72 | 5 | 35777956 | |
| Pubmed | Knockdown of slit signaling during limb development leads to a reduction in humerus length. | 2.30e-04 | 11 | 72 | 2 | 33347679 | |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | COL23A1 TNRC18 SLC16A14 TTLL11 SREBF2 NLGN2 CHD6 XYLB FGGY ADAT2 SHKBP1 | 2.34e-04 | 1489 | 72 | 11 | 28611215 |
| Pubmed | 2.42e-04 | 421 | 72 | 6 | 34650049 | ||
| Pubmed | 2.67e-04 | 60 | 72 | 3 | 26272612 | ||
| Pubmed | 2.75e-04 | 12 | 72 | 2 | 9631292 | ||
| Pubmed | High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint. | 2.75e-04 | 12 | 72 | 2 | 9680377 | |
| Pubmed | 3.25e-04 | 13 | 72 | 2 | 28416489 | ||
| Pubmed | Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1. | 3.39e-04 | 65 | 72 | 3 | 18729074 | |
| Pubmed | Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. | 3.48e-04 | 160 | 72 | 4 | 23798571 | |
| Pubmed | 3.71e-04 | 67 | 72 | 3 | 30669930 | ||
| Pubmed | MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. | 3.88e-04 | 1082 | 72 | 9 | 38697112 | |
| Pubmed | 4.00e-04 | 166 | 72 | 4 | 34687317 | ||
| Pubmed | The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. | 4.36e-04 | 15 | 72 | 2 | 15107403 | |
| Pubmed | Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. | 4.58e-04 | 72 | 72 | 3 | 25917818 | |
| Pubmed | 4.60e-04 | 878 | 72 | 8 | 37223481 | ||
| Pubmed | 5.06e-04 | 484 | 72 | 6 | 31995728 | ||
| Pubmed | 5.58e-04 | 493 | 72 | 6 | 15368895 | ||
| Pubmed | 6.13e-04 | 1153 | 72 | 9 | 29845934 | ||
| Pubmed | 6.26e-04 | 187 | 72 | 4 | 29777862 | ||
| Pubmed | 6.33e-04 | 18 | 72 | 2 | 16247769 | ||
| Pubmed | 6.70e-04 | 82 | 72 | 3 | 20833797 | ||
| Pubmed | Ski regulates Hippo and TAZ signaling to suppress breast cancer progression. | 7.19e-04 | 84 | 72 | 3 | 25670202 | |
| Pubmed | LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. | 7.28e-04 | 942 | 72 | 8 | 31073040 | |
| Pubmed | Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. | 7.32e-04 | 195 | 72 | 4 | 17110338 | |
| Pubmed | 7.60e-04 | 197 | 72 | 4 | 31620119 | ||
| Pubmed | 7.75e-04 | 198 | 72 | 4 | 24337577 | ||
| Pubmed | 7.96e-04 | 87 | 72 | 3 | 33711283 | ||
| Pubmed | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. | 8.28e-04 | 1203 | 72 | 9 | 29180619 | |
| Pubmed | Profiling of Parkin-binding partners using tandem affinity purification. | 8.50e-04 | 203 | 72 | 4 | 24244333 | |
| Pubmed | 9.50e-04 | 22 | 72 | 2 | 35952650 | ||
| Pubmed | Quantitative analysis of PPT1 interactome in human neuroblastoma cells. | 9.64e-04 | 210 | 72 | 4 | 26217791 | |
| Pubmed | 9.96e-04 | 94 | 72 | 3 | 36584595 | ||
| Pubmed | SEC61A2 TNRC18 SLC25A5 SLC25A6 USO1 TTLL11 RCN2 SEC61A1 PGAM5 | 1.07e-03 | 1247 | 72 | 9 | 27684187 | |
| Pubmed | Defining the human deubiquitinating enzyme interaction landscape. | 1.10e-03 | 1005 | 72 | 8 | 19615732 | |
| Pubmed | 1.12e-03 | 377 | 72 | 5 | 25147182 | ||
| Pubmed | USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease. | 1.13e-03 | 565 | 72 | 6 | 33567341 | |
| Pubmed | 1.14e-03 | 378 | 72 | 5 | 34315543 | ||
| Pubmed | Common variants at ten loci influence QT interval duration in the QTGEN Study. | 1.23e-03 | 25 | 72 | 2 | 19305408 | |
| Pubmed | Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment. | 1.23e-03 | 25 | 72 | 2 | 15782160 | |
| Pubmed | Characterization of a novel Lbx1 mouse loss of function strain. | 1.33e-03 | 26 | 72 | 2 | 34906895 | |
| Pubmed | 1.33e-03 | 26 | 72 | 2 | 20301347 | ||
| Pubmed | Identification of Arx transcriptional targets in the developing basal forebrain. | 1.54e-03 | 28 | 72 | 2 | 18799476 | |
| Interaction | CLN3 interactions | 2.71e-06 | 115 | 69 | 6 | int:CLN3 | |
| Interaction | CLN5 interactions | 3.58e-06 | 68 | 69 | 5 | int:CLN5 | |
| Interaction | GABRA1 interactions | 1.35e-05 | 152 | 69 | 6 | int:GABRA1 | |
| GeneFamily | Solute carriers | 2.82e-04 | 395 | 42 | 6 | 752 | |
| GeneFamily | CD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing | 5.43e-04 | 15 | 42 | 2 | 1296 | |
| GeneFamily | CD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing | 4.28e-03 | 42 | 42 | 2 | 602 | |
| GeneFamily | Fibronectin type III domain containing | 6.06e-03 | 160 | 42 | 3 | 555 | |
| Coexpression | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | 1.58e-05 | 194 | 72 | 6 | M10986 | |
| Coexpression | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | SEC61A2 TNRC18 ABCB10 MFHAS1 CD47 SREBF2 NLGN2 IL17RD SEC61A1 SLC39A7 | 1.65e-05 | 681 | 72 | 10 | M5314 |
| Coexpression | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | SEC61A2 TNRC18 ABCB10 MFHAS1 CD47 SREBF2 NLGN2 IL17RD SEC61A1 SLC39A7 | 2.16e-05 | 703 | 72 | 10 | MM1055 |
| Drug | Clodronate | 2.66e-08 | 3 | 69 | 3 | DB00720 | |
| Drug | dehydroabietylamine | 1.06e-07 | 4 | 69 | 3 | ctd:C000600819 | |
| Drug | closantel | 9.24e-07 | 7 | 69 | 3 | ctd:C023342 | |
| Drug | AC1L4X2K | 3.15e-06 | 10 | 69 | 3 | CID000193824 | |
| Drug | oleoylcarnitine | 1.45e-05 | 16 | 69 | 3 | CID006441392 | |
| Drug | beta-hydroxypalmitoyl-CoA | 1.76e-05 | 17 | 69 | 3 | CID000440600 | |
| Drug | carboxyatractyloside | 2.71e-05 | 3 | 69 | 2 | ctd:C003853 | |
| Drug | agaric acid | 2.93e-05 | 20 | 69 | 3 | CID000012629 | |
| Drug | D-cycloserine [68-41-7]; Up 200; 39.2uM; PC3; HT_HG-U133A | 3.14e-05 | 199 | 69 | 6 | 7134_UP | |
| Drug | phenylsuccinate | 3.41e-05 | 21 | 69 | 3 | CID000095459 | |
| Drug | AC1L193Y | 4.55e-05 | 65 | 69 | 4 | CID000000380 | |
| Drug | AC1L1HQD | 5.41e-05 | 4 | 69 | 2 | CID000004244 | |
| Drug | hexadecanal | 6.37e-05 | 226 | 69 | 6 | CID000000984 | |
| Disease | autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology) | 5.11e-08 | 4 | 70 | 3 | DOID:0111517 (implicated_via_orthology) | |
| Disease | hypertrophic cardiomyopathy (implicated_via_orthology) | 4.47e-05 | 29 | 70 | 3 | DOID:11984 (implicated_via_orthology) | |
| Disease | mitochondrial metabolism disease (implicated_via_orthology) | 7.92e-05 | 35 | 70 | 3 | DOID:700 (implicated_via_orthology) | |
| Disease | CHARGE syndrome (implicated_via_orthology) | 1.16e-04 | 7 | 70 | 2 | DOID:0050834 (implicated_via_orthology) | |
| Disease | autism spectrum disorder (implicated_via_orthology) | 4.77e-04 | 152 | 70 | 4 | DOID:0060041 (implicated_via_orthology) | |
| Disease | congenital heart disease (implicated_via_orthology) | 5.99e-04 | 69 | 70 | 3 | DOID:1682 (implicated_via_orthology) | |
| Disease | Phenyllactate (PLA) measurement | 9.24e-04 | 19 | 70 | 2 | EFO_0021662 | |
| Disease | Myasthenic Syndromes, Congenital | 1.48e-03 | 24 | 70 | 2 | C0751882 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| NLASGGAAGATSLCF | 116 | P12236 | |
| AGGLGINLTAADTCI | 1211 | Q9HCK8 | |
| FGGCGSVLNIASADL | 131 | Q7Z6V5 | |
| ESGLLGSCFSQGLAL | 16 | Q8N2A0 | |
| NLASGGAAGATSLCF | 116 | P05141 | |
| TALAGAQGFTGCLSA | 1156 | Q9C0A0 | |
| LGLSAVFLCGAAANA | 216 | Q9NRK6 | |
| LGLSGGLAFEACSGL | 1016 | Q9ULD4 | |
| FCQALGSALGGQSSL | 371 | Q17RM4 | |
| SGDFLLANACNGLAL | 191 | Q86YH6 | |
| SGACLGLLAVAAVAA | 11 | P33151 | |
| GSLVSLSACGAAGGL | 136 | Q8TE56 | |
| LSACGAAGGLVGLIQ | 141 | Q8TE56 | |
| AAAAGRAGGSCQAAQ | 11 | P0C854 | |
| QAAVLNCSLGAAAAG | 51 | Q8TDY8 | |
| GLLLLCAAAAGAGKA | 11 | Q14257 | |
| ALAFGACLGGNGTLI | 771 | Q04671 | |
| ACLGGNGTLIGASAN | 776 | Q04671 | |
| LSSKAGGCGLNLIGA | 571 | Q92698 | |
| AVLAGASAGLCAFQP | 311 | Q86XR2 | |
| GNLLAACGFSSRLTG | 246 | Q504Q3 | |
| VGSLATADLLAGCGL | 111 | P46095 | |
| ACLNGSQLAVAAGGS | 16 | Q8NFM7 | |
| NGLNAGLAFPTGCSL | 211 | P50579 | |
| QLTLTAAGACPGAGA | 31 | Q9Y4C4 | |
| ALSGDQGGCSSILGN | 501 | Q99665 | |
| GSAAACLLLGVQAAA | 46 | Q86Y22 | |
| ALQLAACGLAGGSAA | 6 | Q96HS1 | |
| ACGLAGGSAAVLFSA | 11 | Q96HS1 | |
| CISGDSAGGNLAAAL | 186 | Q6PIU2 | |
| AAFLLALQNGCAGAL | 1191 | Q14999 | |
| VALALGGRGCLGASS | 21 | Q86UK5 | |
| GGLALLCCAAAAAAA | 16 | Q9H1U4 | |
| AGGSLLLCAALLAAG | 11 | Q9BY08 | |
| SCNGAAATADLALGR | 1441 | P55268 | |
| GAAQFVGGLLISSGC | 121 | Q86WI0 | |
| AAALGCIGLVAHAGQ | 601 | Q09013 | |
| AGGLGINLTAADTCI | 861 | Q8TD26 | |
| LVGAAVLGACASGDF | 486 | Q96C11 | |
| GSALLALCGALAACG | 6 | P16870 | |
| AGTGILSIFCAQAGA | 91 | Q96LA8 | |
| AALLLGSACCGSAQL | 6 | Q08722 | |
| IFGSGAGASCVNLLI | 261 | Q8NFZ4 | |
| TADECGLLQAGLASG | 21 | Q5SV97 | |
| LAGDSAGGNLCFTVA | 721 | Q05469 | |
| GNSVSAGQLLCGGLF | 416 | O60763 | |
| AGQLLCGGLFSTDSL | 421 | O60763 | |
| VAAAASGANTLAGGL | 361 | Q6ZRF8 | |
| AAFGGLCIGALSVLA | 421 | Q9H9S3 | |
| AGLAVICALIGFSSG | 406 | Q7RTX9 | |
| GNLGTILRSAAGAGC | 221 | Q9HC36 | |
| NLSASCGSALRAAAG | 76 | Q96T51 | |
| DAAGSFLLLGCNNGS | 331 | Q8TBC3 | |
| VNACLGAGLLNFPAA | 61 | Q9NVC3 | |
| LGFSQGAALAALVCA | 116 | Q8WZ82 | |
| GAALAALVCALGQAG | 121 | Q8WZ82 | |
| AAARAADAACNGLPG | 136 | A6NEL2 | |
| NLASGGAAGATSLCF | 116 | P12235 | |
| AALCLGNAAGEAAPG | 16 | Q8NE01 | |
| LLAGLGLSSAAGSCG | 106 | Q9Y3P4 | |
| SVLNSAEGGLLGSCA | 251 | Q9NZR4 | |
| CGGGLLEAQALSATG | 1196 | O15417 | |
| GGGAAAAAAVALALA | 71 | Q8NHH1 | |
| LSLLCGNGSVGDNAL | 101 | P51786 | |
| CLARLSLATAGGGNA | 91 | M0QZC1 | |
| CALALGNCALHGGQA | 226 | Q6SZW1 | |
| AAFGGLCIGALSVLA | 421 | P61619 | |
| ALAGTACALLTEGGA | 391 | Q92504 | |
| PAFLAGSGAACGALL | 891 | Q96MS0 | |
| GSGAACGALLLGLCA | 896 | Q96MS0 | |
| AAAAGNLQTCLAVLG | 591 | Q12772 | |
| AAVGGAQALSCLTGS | 151 | O75191 | |
| QLGCGRAVAALGAAA | 826 | Q4G0T1 | |
| TAFSAGGVLAGALCN | 556 | Q4J6C6 | |
| GAQLAAAAAGSLGCS | 391 | Q96F45 | |
| AGAGGASILATAANL | 181 | O75204 | |
| GLLGGSCAAAASVVN | 56 | A6NJT0 | |
| GLTLLFASGDSGAGC | 351 | O14773 |