Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2B2 ATP2B3 ATP2B4	5.09e-06	11	64	3	GO:0005388
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPC5 PKD1L2 ATP2B2 ATP2B3 ATP2B4	1.23e-04	151	64	5	GO:0015085
GeneOntologyMolecularFunction	extracellularly glycine-gated ion channel activity	GLRA1 GLRA3	1.50e-04	6	64	2	GO:0016933
GeneOntologyMolecularFunction	extracellularly glycine-gated chloride channel activity	GLRA1 GLRA3	1.50e-04	6	64	2	GO:0016934
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP2B2 ATP2B3 ATP2B4	2.08e-04	36	64	3	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP2B2 ATP2B3 ATP2B4	2.08e-04	36	64	3	GO:0015662
GeneOntologyMolecularFunction	inhibitory extracellular ligand-gated monoatomic ion channel activity	GLRA1 GLRA3	2.80e-04	8	64	2	GO:0005237
GeneOntologyMolecularFunction	protein phosphatase 2B binding	AKAP1 ATP2B4	4.48e-04	10	64	2	GO:0030346
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC26A4 GLRA1 TRPC5 GLRA3 TMEM63B PKD1L2 ATP2B2 ATP2B3 ATP2B4	6.62e-04	758	64	9	GO:0015318
GeneOntologyMolecularFunction	glycine binding	GLRA1 GLRA3	8.98e-04	14	64	2	GO:0016594
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC26A4 GLRA1 TRPC5 GLRA3 TMEM63B PKD1L2 ATP2B2 ATP2B3 ATP2B4	9.13e-04	793	64	9	GO:0015075
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP2B2 ATP2B3 ATP2B4	1.04e-03	62	64	3	GO:0019829
GeneOntologyBiologicalProcess	regulation of cytosolic calcium ion concentration	TRPC5 SYNPO ATP2B2 ATP2B3 ATP2B4	6.27e-06	84	64	5	GO:0051480
GeneOntologyBiologicalProcess	cellular response to alcohol	UGT1A1 GLRA1 GLRA3 ADCY2 KLF2	5.21e-05	130	64	5	GO:0097306
GeneOntologyBiologicalProcess	cellular response to ethanol	UGT1A1 GLRA1 GLRA3	6.24e-05	25	64	3	GO:0071361
GeneOntologyBiologicalProcess	protein retention in Golgi apparatus	VPS13D VPS13C	9.42e-05	5	64	2	GO:0045053
GeneOntologyBiologicalProcess	regulation of cardiac conduction	ATP2B2 ATP2B3 ATP2B4	9.83e-05	29	64	3	GO:1903779
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3 ATP2B4	1.53e-07	4	64	3	IPR022141
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3 ATP2B4	1.53e-07	4	64	3	PF12424
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B3 ATP2B4	1.53e-07	4	64	3	IPR006408
Domain	-	ATP2B2 ATP2B3 ATP2B4	2.08e-05	16	64	3	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP2B2 ATP2B3 ATP2B4	2.08e-05	16	64	3	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP2B2 ATP2B3 ATP2B4	2.52e-05	17	64	3	IPR006068
Domain	Cation_ATPase_C	ATP2B2 ATP2B3 ATP2B4	2.52e-05	17	64	3	PF00689
Domain	Cation_ATPase_N	ATP2B2 ATP2B3 ATP2B4	3.02e-05	18	64	3	PF00690
Domain	Cation_ATPase_N	ATP2B2 ATP2B3 ATP2B4	3.02e-05	18	64	3	SM00831
Domain	VPS13	VPS13D VPS13C	3.46e-05	3	64	2	IPR026847
Domain	VPS13_mid_rpt	VPS13D VPS13C	3.46e-05	3	64	2	PF16910
Domain	VPS13	VPS13D VPS13C	3.46e-05	3	64	2	PF16908
Domain	VPS13_N2	VPS13D VPS13C	3.46e-05	3	64	2	IPR031646
Domain	VPS13_mid_rpt	VPS13D VPS13C	3.46e-05	3	64	2	IPR031642
Domain	ATPase_P-typ_cation-transptr_N	ATP2B2 ATP2B3 ATP2B4	3.58e-05	19	64	3	IPR004014
Domain	Glycine_rcpt_A	GLRA1 GLRA3	6.90e-05	4	64	2	IPR008127
Domain	VPS13_C	VPS13D VPS13C	6.90e-05	4	64	2	PF16909
Domain	SHR-BD	VPS13D VPS13C	6.90e-05	4	64	2	IPR009543
Domain	VPS13_C	VPS13D VPS13C	6.90e-05	4	64	2	IPR031645
Domain	SHR-BD	VPS13D VPS13C	6.90e-05	4	64	2	PF06650
Domain	HAD-like_dom	CTDNEP1 ATP2B2 ATP2B3 ATP2B4	1.55e-04	79	64	4	IPR023214
Domain	ATPase_P-typ_cyto_domN	ATP2B2 ATP2B3 ATP2B4	2.32e-04	35	64	3	IPR023299
Domain	P_typ_ATPase	ATP2B2 ATP2B3 ATP2B4	2.53e-04	36	64	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP2B2 ATP2B3 ATP2B4	2.53e-04	36	64	3	IPR018303
Domain	ATPASE_E1_E2	ATP2B2 ATP2B3 ATP2B4	2.53e-04	36	64	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP2B2 ATP2B3 ATP2B4	2.74e-04	37	64	3	IPR008250
Domain	E1-E2_ATPase	ATP2B2 ATP2B3 ATP2B4	2.74e-04	37	64	3	PF00122
Domain	VPS13_N	VPS13D VPS13C	3.19e-04	8	64	2	IPR026854
Domain	Chorein_N	VPS13D VPS13C	3.19e-04	8	64	2	PF12624
Domain	Hydrolase_3	ATP2B2 ATP2B3	5.11e-04	10	64	2	PF08282
Domain	TUDOR	TDRD15 AKAP1	1.02e-03	14	64	2	PF00567
Domain	GABAA/Glycine_rcpt	GLRA1 GLRA3	2.79e-03	23	64	2	IPR006028
Domain	TUDOR	TDRD15 AKAP1	2.79e-03	23	64	2	PS50304
Domain	TUDOR	TDRD15 AKAP1	3.84e-03	27	64	2	SM00333
Domain	Tudor	TDRD15 AKAP1	4.73e-03	30	64	2	IPR002999
Domain	TIG	PLXNC1 CAMTA2	5.04e-03	31	64	2	PF01833
Domain	IPT	PLXNC1 CAMTA2	5.37e-03	32	64	2	IPR002909
Domain	FIBRINOGEN_C_1	CNTNAP5 ANGPTL3	5.37e-03	32	64	2	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP5 ANGPTL3	5.37e-03	32	64	2	IPR002181
Domain	FIBRINOGEN_C_2	CNTNAP5 ANGPTL3	5.37e-03	32	64	2	PS51406
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	ATP2B2 ATP2B3 ATP2B4	5.71e-06	12	43	3	M27326
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	ATP2B2 ATP2B3 ATP2B4	9.40e-06	14	43	3	MM15052
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	ATP2B2 ATP2B3 ATP2B4	7.35e-05	27	43	3	MM15053
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	ATP2B2 ATP2B3 ATP2B4	8.21e-05	28	43	3	M924
Pathway	WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION	ATP2B2 ATP2B3 ATP2B4	1.76e-04	36	43	3	M39831
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	PLCZ1 ATP2B2 ATP2B3 ADCY2 ATP2B4	1.98e-04	178	43	5	M2890
Pathway	REACTOME_ION_HOMEOSTASIS	ATP2B2 ATP2B3 ATP2B4	5.88e-04	54	43	3	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	ATP2B2 ATP2B3 ATP2B4	5.88e-04	54	43	3	MM15202
Pathway	REACTOME_NEDDYLATION	FBXO10 SOCS5 COPS3 FEM1A NPLOC4	5.94e-04	226	43	5	MM15543
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP2B2 ATP2B3 ATP2B4	6.21e-04	55	43	3	M971
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP2B2 ATP2B3 ATP2B4	6.90e-04	57	43	3	MM15643
Pathway	REACTOME_NEDDYLATION	FBXO10 SOCS5 COPS3 FEM1A NPLOC4	8.55e-04	245	43	5	M27822
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	12209837
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	12784250
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	15101689
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	8245032
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	8634322
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	11152753
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B2 ATP2B3 ATP2B4	2.49e-08	4	65	3	10434059
Pubmed	Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.	ATP2B2 ATP2B3 ATP2B4	6.21e-08	5	65	3	17938178
Pubmed	Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.	ATP2B2 ATP2B3 ATP2B4	1.24e-07	6	65	3	12767889
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2B2 ATP2B3 ATP2B4	3.47e-07	8	65	3	10951186
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	TRPC5 ATP2B2 ATP2B3 ATP2B4	7.82e-07	38	65	4	30786075
Pubmed	Characterization of the glycinergic input to bipolar cells of the mouse retina.	GLRA1 GLRA3	3.44e-06	2	65	2	16420443
Pubmed	Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse.	GLRA1 GLRA3	3.44e-06	2	65	2	21486794
Pubmed	Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site.	GLRA1 GLRA3	3.44e-06	2	65	2	23834509
Pubmed	Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain.	TCF4 TCF12	3.44e-06	2	65	2	7984047
Pubmed	Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.	ATP2B2 ATP2B3	3.44e-06	2	65	2	8187550
Pubmed	The role of E-proteins in B- and T-lymphocyte development.	TCF4 TCF12	3.44e-06	2	65	2	9618760
Pubmed	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.	ATP2B2 ATP2B4	3.44e-06	2	65	2	1313367
Pubmed	Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.	ATP2B3 ATP2B4	3.44e-06	2	65	2	1531651
Pubmed	Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.	ATP2B2 ATP2B4	3.44e-06	2	65	2	22252018
Pubmed	Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.	ATP2B2 ATP2B4	3.44e-06	2	65	2	25690014
Pubmed	The Concerted Action of E2-2 and HEB Is Critical for Early Lymphoid Specification.	TCF4 TCF12	3.44e-06	2	65	2	30936870
Pubmed	Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting.	GLRA1 GLRA3	3.44e-06	2	65	2	19959465
Pubmed	Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.	ATP2B2 ATP2B4	3.44e-06	2	65	2	16216224
Pubmed	The helix-loop-helix gene E2A is required for B cell formation.	TCF4 TCF12	1.03e-05	3	65	2	8001124
Pubmed	Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.	TCF4 TCF12	1.03e-05	3	65	2	30593567
Pubmed	Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development.	TCF4 TCF12	1.03e-05	3	65	2	18854153
Pubmed	ALF1, a basic helix-loop-helix transcription factor, maps to mouse chromosome 9.	TCF4 TCF12	1.03e-05	3	65	2	8833258
Pubmed	E2-2 regulates the expansion of pro-B cells and follicular versus marginal zone decisions.	TCF4 TCF12	1.03e-05	3	65	2	17082585
Pubmed	Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1.	FBXO10 FRMD4B	1.03e-05	3	65	2	11445584
Pubmed	The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.	ATP2B2 ATP2B4	1.03e-05	3	65	2	17689535
Pubmed	Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells.	ATP2B2 ATP2B4	1.03e-05	3	65	2	20211863
Pubmed	Diversity of glycine receptors in the mouse retina: localization of the alpha4 subunit.	GLRA1 GLRA3	1.03e-05	3	65	2	17154252
Pubmed	Murine helix-loop-helix transcriptional activator proteins binding to the E-box motif of the Akv murine leukemia virus enhancer identified by cDNA cloning.	TCF4 TCF12	1.03e-05	3	65	2	1321336
Pubmed	A role for E2-2 at the DN3 stage of early thymopoiesis.	TCF4 TCF12	1.03e-05	3	65	2	18384878
Pubmed	Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice.	GLRA1 GLRA3	1.03e-05	3	65	2	17920294
Pubmed	ME1 and GE1: basic helix-loop-helix transcription factors expressed at high levels in the developing nervous system and in morphogenetically active regions.	TCF4 TCF12	1.03e-05	3	65	2	8261111
Pubmed	B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.	TCF4 TCF12	1.03e-05	3	65	2	8649400
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	TDRD15 RAPGEF6 BBX PKD1L2 BIRC6	1.62e-05	168	65	5	30631154
Pubmed	Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains.	TCF4 TCF12	2.06e-05	4	65	2	11802795
Pubmed	Glycinergic input of widefield, displaced amacrine cells of the mouse retina.	GLRA1 GLRA3	2.06e-05	4	65	2	19528249
Pubmed	Expression and mRNA splicing of glycine receptor subunits and gephyrin during neuronal differentiation of P19 cells in vitro, studied by RT-PCR and immunocytochemistry.	GLRA1 GLRA3	2.06e-05	4	65	2	9051263
Pubmed	Activation of glycine receptor phase-shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus.	GLRA1 GLRA3	2.06e-05	4	65	2	21486797
Pubmed	Analysis of the human VPS13 gene family.	VPS13D VPS13C	2.06e-05	4	65	2	15498460
Pubmed	SCL binds the human homologue of DRG in vivo.	TCF4 TCF12	2.06e-05	4	65	2	9824680
Pubmed	Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.	GLRA1 GLRA3	2.06e-05	4	65	2	28883437
Pubmed	Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.	TCF4 TCF12	2.06e-05	4	65	2	21771727
Pubmed	The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system.	TCF4 TCF12	2.06e-05	4	65	2	16549780
Pubmed	Mutations affecting the BHLHA9 DNA-binding domain cause MSSD, mesoaxial synostotic syndactyly with phalangeal reduction, Malik-Percin type.	TCF4 TCF12	2.06e-05	4	65	2	25466284
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP2B2 ATP2B3 ATP2B4	2.20e-05	29	65	3	15071553
Pubmed	Developmental regulation of glycine receptors at efferent synapses of the murine cochlea.	GLRA1 GLRA3	3.43e-05	5	65	2	21850450
Pubmed	Physical and functional interactions between the transcriptional inhibitors Id3 and ITF-2b. Evidence toward a novel mechanism regulating muscle-specific gene expression.	TCF4 TCF12	3.43e-05	5	65	2	8999959
Pubmed	Native glycine receptor subtypes and their physiological roles.	GLRA1 GLRA3	3.43e-05	5	65	2	18721822
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	VPS13C UBE3C ATP2B2 ATP2B3 NPLOC4	4.60e-05	209	65	5	26389662
Pubmed	Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.	ATP2B2 ATP2B4	5.13e-05	6	65	2	12763866
Pubmed	Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.	ATP2B2 ATP2B4	5.13e-05	6	65	2	11274188
Pubmed	Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.	TCF4 TCF12	5.13e-05	6	65	2	9584154
Pubmed	The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms.	TCF4 TCF12	5.13e-05	6	65	2	10611232
Pubmed	The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors.	TCF4 TCF12	5.13e-05	6	65	2	17878293
Pubmed	Differential cooperation between dHAND and three different E-proteins.	TCF4 TCF12	5.13e-05	6	65	2	15351717
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	GLE1 VPS13C N4BP1 UBE3C AKAP1 BIRC6 FRMD4B GOLGA4	6.56e-05	733	65	8	34672954
Pubmed	Glycine receptors support excitatory neurotransmitter release in developing mouse visual cortex.	GLRA1 GLRA3	7.18e-05	7	65	2	22988142
Pubmed	E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein.	TCF4 TCF12	7.18e-05	7	65	2	8759016
Pubmed	ID1 and CEBPA coordinate epidermal progenitor cell differentiation.	TCF4 TCF12	7.18e-05	7	65	2	36330928
Pubmed	K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.	UBE3C NPLOC4	9.56e-05	8	65	2	25752573
Pubmed	TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.	TCF4 TCF12	9.56e-05	8	65	2	32179550
Pubmed	GSK3 temporally regulates neurogenin 2 proneural activity in the neocortex.	TCF4 TCF12	9.56e-05	8	65	2	22674256
Pubmed	Sgn1, a basic helix-loop-helix transcription factor delineates the salivary gland duct cell lineage in mice.	TCF4 TCF12	9.56e-05	8	65	2	11784080
Pubmed	E protein dosage influences brain development more than family member identity.	TCF4 TCF12	9.56e-05	8	65	2	18214987
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TDRD15 THADA TCF12 BBX VPS13C AKAP1 BIRC6 GOLGA4	9.83e-05	777	65	8	35844135
Pubmed	Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression.	TCF4 GLRA3	1.23e-04	9	65	2	35535852
Pubmed	HEB and E2A function as SMAD/FOXH1 cofactors.	TCF4 TCF12	1.53e-04	10	65	2	21828274
Pubmed	Bmp4 from the optic vesicle specifies murine retina formation.	INMT FGF19	1.87e-04	11	65	2	25792196
Pubmed	Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.	MRTFB SYNPO	2.65e-04	13	65	2	29114040
Pubmed	Genome-wide and candidate gene association study of cigarette smoking behaviors.	BBX TRPC5	2.65e-04	13	65	2	19247474
Pubmed	Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.	TCF4 TCF12	2.65e-04	13	65	2	9242638
Pubmed	O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.	MRTFB SYNPO	3.08e-04	14	65	2	16452088
Pubmed	E protein silencing by the leukemogenic AML1-ETO fusion protein.	TCF4 TCF12	3.08e-04	14	65	2	15333839
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VPS13D THADA SOCS5 N4BP1 BIRC6 MED12	3.20e-04	493	65	6	15368895
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	TCF4 TCF12 PLXNC1 COPS3 BIRC6 ZNF292 KLF2	3.55e-04	709	65	7	22988430
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	THADA MRTFB VPS13C ENAH TMEM63B SYNPO UBE3C DAGLA NPLOC4 GOLGA4	4.20e-04	1489	65	10	28611215
Pubmed	A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo.	TCF4 FGF19	4.59e-04	17	65	2	12361972
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VPS13C SYNPO INO80 DAGLA FRMD4B NPLOC4	4.65e-04	529	65	6	14621295
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TCF4 VPS13D TCF12 BBX ENAH UBE3C	4.99e-04	536	65	6	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TCF4 VPS13D TCF12 BBX ENAH UBE3C	5.08e-04	538	65	6	10512203
Pubmed	TIF1gamma controls erythroid cell fate by regulating transcription elongation.	TCF4 TCF12	5.16e-04	18	65	2	20603019
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	RAPGEF6 VPS13C	5.16e-04	18	65	2	27984743
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	VPS13D PLXNC1 COPS3	5.90e-04	87	65	3	37495603
Pubmed	ETO2 coordinates cellular proliferation and differentiation during erythropoiesis.	TCF4 TCF12	6.39e-04	20	65	2	16407974
Pubmed	Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon.	TCF4 TCF12	6.39e-04	20	65	2	37684687
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	VPS13D MRTFB VPS13C AKAP1 NPLOC4 GOLGA4	6.75e-04	568	65	6	37774976
Pubmed	Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.	SOCS5 ADCY2	7.76e-04	22	65	2	24376456
Pubmed	Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.	UGT1A1 GYS2	8.48e-04	23	65	2	27531557
Pubmed	The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.	THADA TCF12 SLC26A4	8.60e-04	99	65	3	19730683
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SOCS5 N4BP1 DAGLA	9.37e-04	102	65	3	9734811
Pubmed	A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.	TCF4 TCF12 BBX	9.37e-04	102	65	3	19741146
Interaction	CYP2B6 interactions	ATP2B2 ATP2B3 ATP2B4	1.69e-06	8	64	3	int:CYP2B6
Interaction	C17orf78 interactions	ATP2B2 ATP2B3 ATP2B4	6.58e-06	12	64	3	int:C17orf78
Interaction	HSD17B6 interactions	ATP2B2 ATP2B3 ATP2B4	1.35e-05	15	64	3	int:HSD17B6
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B3 ATP2B4	1.04e-06	9	43	3	1209
GeneFamily	Glycine receptors	GLRA1 GLRA3	5.50e-05	5	43	2	868
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	CMYA5 AKAP1	2.15e-03	29	43	2	396
GeneFamily	Tudor domain containing	TDRD15 AKAP1	3.49e-03	37	43	2	780
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	GRK2 RNF19A VPS13C N4BP1 TAPBP GOLGA4 ZNF292	1.56e-08	197	65	7	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	GRK2 RNF19A VPS13C N4BP1 TAPBP GOLGA4 ZNF292	1.61e-08	198	65	7	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GRK2 RNF19A VPS13C N4BP1 TAPBP GOLGA4 ZNF292	1.61e-08	198	65	7	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-B-B_memory\|COVID-19_Severe / Disease, condition lineage and cell class	TCF4 FBXO10 IGHG2 GLRA3 SYNPO SYBU	4.62e-07	199	65	6	24c05faa825c9d55279956469862440f9914a280
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	GRK2 RNF19A VPS13C N4BP1 TAPBP KLF2	4.75e-07	200	65	6	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory\|bone_marrow / Manually curated celltypes from each tissue	TCF4 FBXO10 IGHG2 SLC26A4 SYNPO	4.19e-06	164	65	5	746833f74095c0f25ce76baf1069f1848c231933
ToppCell	Influenza_Severe-B_memory\|Influenza_Severe / Disease group and Cell class	TCF4 FBXO10 IGHG2 SYNPO SYBU	4.32e-06	165	65	5	51172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCell	severe_influenza-B_memory\|World / disease group, cell group and cell class (v2)	TCF4 FBXO10 IGHG2 SYNPO SYBU	5.29e-06	172	65	5	0ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCell	severe-B_memory\|severe / disease stage, cell group and cell class	TCF4 FBXO10 IGHG2 GLRA3 SYBU	5.44e-06	173	65	5	3a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCell	severe-B_memory\|World / disease stage, cell group and cell class	TCF4 FBXO10 IGHG2 GLRA3 SYBU	5.91e-06	176	65	5	4e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCell	severe_influenza-B_memory\|severe_influenza / disease group, cell group and cell class (v2)	TCF4 FBXO10 IGHG2 SYNPO SYBU	6.77e-06	181	65	5	92e572c92109a6dae0f73138c57c3bbd2e0a2f36
ToppCell	3'_v3-blood-Lymphocytic_B-Memory_B_cells\|blood / Manually curated celltypes from each tissue	TDRD15 TCF4 IGHG2 SYNPO SYBU	7.14e-06	183	65	5	e3a418b745d7f040adf47be9e1043b945cae47ed
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 VPS13C BIRC6 GOLGA4 KLF2	7.33e-06	184	65	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 FBXO10 IGHG2 GLRA3 SYNPO	7.53e-06	185	65	5	91c9a3ea1afd97d35bd05648875d29b35fe09128
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IGHG2 GLRA3 SYNPO SYBU	7.93e-06	187	65	5	43f81863063509337bd56a67010c62fb51109bd5
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	TCF4 IGHG2 GLRA3 SYNPO SYBU	7.93e-06	187	65	5	ea56cfca919a09db852b7ee5e42323f822962465
ToppCell	COVID-19_Severe-B_memory\|World / disease group, cell group and cell class	TCF4 FBXO10 IGHG2 GLRA3 SYNPO	7.93e-06	187	65	5	f29c71f2505bb64f3010ada491d422b87a6f7db3
ToppCell	ILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TCF4 RNF19A IGHG2 TAPBP GOLGA4	8.14e-06	188	65	5	2156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IGHG2 GLRA3 SYNPO SYBU	8.14e-06	188	65	5	b6ae707b033a17c75ca81f9194631ead1b63d170
ToppCell	Control-B_intermediate-14\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TDRD15 TCF4 GLRA3 SH3BP5 KLF2	8.79e-06	191	65	5	33fce8e086601e636e8c6ef2ab58fcfdd52af369
ToppCell	COVID-19_Convalescent-Lymphoid_B-B_memory\|COVID-19_Convalescent / Disease group, lineage and cell class	TCF4 IGHG2 GLRA3 SYNPO SYBU	8.79e-06	191	65	5	4a853cd2434b0f5b18e1f853c37515845046c88b
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCF4 MRTFB SYBU ATP2B4 SH3BP5	9.24e-06	193	65	5	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory\|lymph-node_spleen / Manually curated celltypes from each tissue	TCF4 PLXNC1 IGHG2 SYNPO SH3BP5	9.48e-06	194	65	5	b57ae94a092b58623a244a258b4659a3864542c7
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-B-B_memory\|COVID-19_Convalescent / Disease, condition lineage and cell class	TCF4 IGHG2 GLRA3 SYNPO SYBU	1.07e-05	199	65	5	5bbda86486910d053ca51b9caee487d78f6462cb
ToppCell	Influenza-Influenza_Severe-Lymphocyte-B-B_memory\|Influenza_Severe / Disease, condition lineage and cell class	TCF4 FBXO10 IGHG2 SYNPO SYBU	1.07e-05	199	65	5	bf0285f68c9cb1417fc070abc3cb224d07407e0e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CNTNAP5 SLC26A4 TRPC5 SYNPO	5.70e-05	143	65	4	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	IGHG2 GLRA3 ZNF292 KLF2	8.81e-05	160	65	4	5744cd30709f38e84f7ec8893dc19d7a288b465a
ToppCell	Influenza_Severe-B_memory\|World / Disease group and Cell class	TCF4 FBXO10 IGHG2 SYNPO	9.24e-05	162	65	4	21eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_memory\|bone_marrow / Manually curated celltypes from each tissue	TCF4 IGHG2 GLRA3 SYNPO	9.46e-05	163	65	4	30f5c93c4e170304d701b5231f0d545f404066f7
ToppCell	mild_COVID-19_(asymptomatic)-B_intermediate\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TDRD15 TCF4 FBXO10 IGHG2	1.02e-04	166	65	4	8de8f388f24436b84e19ef460476fdbda4d16abf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 INMT SYNPO KLF2	1.02e-04	166	65	4	ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 FBXO10 IGHG2 SYNPO	1.24e-04	175	65	4	1b3510e9078eec7cfc5805043e435e9e5e0f0877
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TCF4 INMT ENAH KLF2	1.24e-04	175	65	4	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell	COVID-19_Moderate-B_intermediate\|COVID-19_Moderate / disease group, cell group and cell class	TCF4 IGHG2 TRPC5 SYNPO	1.30e-04	177	65	4	68e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCell	Healthy-B_memory\|World / disease group, cell group and cell class	TCF4 IGHG2 GLRA3 SYBU	1.33e-04	178	65	4	b4848b95f2b449c9fac9b5560d959af1788a6f3b
ToppCell	COVID-19_Moderate-B_memory\|World / disease group, cell group and cell class	TCF4 IGHG2 SYNPO SYBU	1.39e-04	180	65	4	2f37187b866edb56410c2334b72713f2248dc335
ToppCell	COVID-19_Moderate-B_intermediate\|World / disease group, cell group and cell class	TCF4 IGHG2 TRPC5 SYNPO	1.39e-04	180	65	4	bd81b87a6dc81e5ab4a6c948eb0c80f14401a6a7
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF4 PLXNC1 GLRA3 SH3BP5	1.39e-04	180	65	4	eedb6d89680f968167afb1dcd132c9de9096b50f
ToppCell	Healthy-B_memory\|Healthy / disease group, cell group and cell class	TCF4 IGHG2 GLRA3 SYBU	1.42e-04	181	65	4	7b903076efb90026b9845af0c7a840901451193a
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRTFB SYNPO ATP2B2 ATP2B4	1.45e-04	182	65	4	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	severe_influenza-B_intermediate\|World / disease group, cell group and cell class (v2)	TCF4 IGHG2 SYNPO SH3BP5	1.45e-04	182	65	4	e633a908a2fb30ed362cf22fbb8d6839f31f1751
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRTFB SYNPO ATP2B2 ATP2B4	1.45e-04	182	65	4	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TDRD15 TCF4 IGHG2 GLRA3	1.48e-04	183	65	4	ffa831f67ed005f05d1b80ebc707e046fc08e22f
ToppCell	(1)_T_cells-(1)_T_regulatory\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	THADA GYS2 ANGPTL3 FRMD4B	1.51e-04	184	65	4	3cbf81757653652441843d85cb7ec1dcf25ca1b0
ToppCell	COPD-Endothelial-VE_Capillary_A\|COPD / Disease state, Lineage and Cell class	TCF4 INMT SYNPO ATP2B4	1.51e-04	184	65	4	5f4f7775d488ececf086c71441defecbee9d8a9c
ToppCell	Control-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	THADA RAPGEF6 FRMD4B ZNF292	1.54e-04	185	65	4	e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IGHG2 GLRA3 SYBU	1.54e-04	185	65	4	05e6eb78ead81268c1656e7ffe34f9cb7329b908
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	RNF19A VPS13C BIRC6 ZNF292	1.54e-04	185	65	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	COPD-Lymphoid-T_Regulatory\|COPD / Disease state, Lineage and Cell class	THADA RAPGEF6 RNF19A ZNF292	1.54e-04	185	65	4	846403edd4c8f646201d519055198fc38b7ffff9
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF4 MRTFB ATP2B4 KLF2	1.54e-04	185	65	4	fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	RNF19A VPS13C BIRC6 ZNF292	1.57e-04	186	65	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF4 FBXO10 IGHG2 KLF2	1.57e-04	186	65	4	55b239834b96b1f7787ec77a7d19796d617bbbf0
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRTFB SYNPO ATP2B2 ATP2B4	1.57e-04	186	65	4	5302399825f213d105ac70b91366a4513b732838
ToppCell	Control-Lymphoid_B-B_memory\|Control / Disease group, lineage and cell class	TCF4 IGHG2 SYNPO SYBU	1.64e-04	188	65	4	ba4245de3bee29118abab57c4fce60b2007a189c
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IGHG2 SYNPO SYBU	1.64e-04	188	65	4	9256c5f45c97df209bb9c322c3b557d4f726a333
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	TCF4 MRTFB INMT SH3BP5	1.64e-04	188	65	4	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	10x5'-blood-Lymphocytic_B-Memory_B_cells\|blood / Manually curated celltypes from each tissue	TCF4 IGHG2 SYNPO SYBU	1.67e-04	189	65	4	8aa65ffc396ccc5e86a6d38b99a2d51c34c9b6d2
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 IGHG2 SYNPO SYBU	1.67e-04	189	65	4	ac0203f17b481d608587113ea2de0f383b29ed27
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCF4 MRTFB SYBU SH3BP5	1.71e-04	190	65	4	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	THADA RNF19A N4BP1 ZNF292	1.71e-04	190	65	4	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TCF4 MRTFB INMT SH3BP5	1.71e-04	190	65	4	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	remission-B_memory\|World / disease stage, cell group and cell class	TCF4 IGHG2 SYNPO SYBU	1.71e-04	190	65	4	c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TCF4 IGHG2 SYNPO SYBU	1.74e-04	191	65	4	03f6da73e7b706252d2096507222229c4101a27b
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	THADA RAPGEF6 FRMD4B ZNF292	1.74e-04	191	65	4	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IGHG2 SYNPO SYBU	1.74e-04	191	65	4	578b58782e816ecaeabfbc616ceb1dcd53ee428b
ToppCell	severe_COVID-19-B_memory\|World / disease group, cell group and cell class (v2)	TCF4 FBXO10 IGHG2 SYNPO	1.74e-04	191	65	4	3b57e353b74ebc866d0e11deeba31fa764c42325
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	RNF19A VPS13C BIRC6 ZNF292	1.74e-04	191	65	4	9454f642c3621370fa23640b631301346b300950
ToppCell	Control-B_intermediate-14\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TDRD15 TCF4 IGHG2 SH3BP5	1.74e-04	191	65	4	076302fd247aab6c0b187ac9e0c67a3ba46414ba
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IGHG2 SYNPO SYBU	1.78e-04	192	65	4	debd471f61cf3606b8e9c246add0be5df601af7f
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TCF4 SYNPO SH3BP5 KLF2	1.78e-04	192	65	4	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	COVID-19_Mild-Lymphoid_B-B_memory\|COVID-19_Mild / Disease group, lineage and cell class	TCF4 IGHG2 SYNPO SYBU	1.78e-04	192	65	4	d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TCF4 IGHG2 SYNPO SYBU	1.78e-04	192	65	4	314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell	Healthy_donor-B_intermediate\|World / disease group, cell group and cell class (v2)	TDRD15 TCF4 IGHG2 GLRA3	1.78e-04	192	65	4	f77007b284e11f8654ad599eef929df7c6c4ebf0
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 PLXNC1 SH3BP5 KLF2	1.78e-04	192	65	4	d525f7f088a53110912600a7c9f6d33b9270d534
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 PLXNC1 SH3BP5 KLF2	1.78e-04	192	65	4	2bfac6b3956265205ca47d06888851ed68b65999
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CNTNAP5 TRPC5 ATP2B2 ATP2B3	1.78e-04	192	65	4	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	mild_COVID-19-B_memory\|World / disease group, cell group and cell class (v2)	TCF4 IGHG2 SYNPO SYBU	1.81e-04	193	65	4	69b70c838328fdc7dbb6b5449fe2811a5389a839
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF4 IGHG2 SYNPO SYBU	1.81e-04	193	65	4	de0213f2105b814f38ffbfd004ea7603230eed68
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 PLXNC1 ATP2B4 KLF2	1.81e-04	193	65	4	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	mild_COVID-19-B_memory\|mild_COVID-19 / disease group, cell group and cell class (v2)	TCF4 IGHG2 SYNPO SYBU	1.81e-04	193	65	4	7e6fe70928a50b0a8f12220e572c07c5670d092e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 SYNPO SH3BP5 KLF2	1.81e-04	193	65	4	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	RNF19A N4BP1 GOLGA4 ZNF292	1.81e-04	193	65	4	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	COVID-19_Severe-B_memory\|COVID-19_Severe / disease group, cell group and cell class	IGHG2 GLRA3 SYNPO KLF2	1.88e-04	195	65	4	54becd9e283639638fc5f13eddce224aed9391da
ToppCell	Control-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 RNF19A ATP2B4 FRMD4B	1.88e-04	195	65	4	6687e579582d7a239bee80846de0cf827a6f6a62
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCF4 RNF19A ZNF292 KLF2	1.88e-04	195	65	4	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	CV-Moderate-6\|Moderate / Virus stimulation, Condition and Cluster	RNF19A CTDNEP1 ZNF292 KLF2	1.88e-04	195	65	4	2b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 SYNPO SH3BP5 KLF2	1.92e-04	196	65	4	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 RNF19A ATP2B4 FRMD4B	1.92e-04	196	65	4	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	TCF4 BBX FRMD4B ZNF292	1.92e-04	196	65	4	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 FRMD4B SH3BP5 KLF2	1.92e-04	196	65	4	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 FRMD4B SH3BP5 KLF2	1.92e-04	196	65	4	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 SYNPO SH3BP5 KLF2	1.92e-04	196	65	4	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 RNF19A ATP2B4 FRMD4B	1.92e-04	196	65	4	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	TCF4 BBX FRMD4B ZNF292	1.92e-04	196	65	4	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 SYNPO SH3BP5 KLF2	1.92e-04	196	65	4	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP5 MRTFB ATP2B2 ADCY2	2.00e-04	198	65	4	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	TCF4 SYNPO SH3BP5 KLF2	2.00e-04	198	65	4	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP5 MRTFB SYBU ATP2B2	2.00e-04	198	65	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Endoth-Vasc\|World / shred by cell class for parenchyma	TCF4 MRTFB SH3BP5 KLF2	2.00e-04	198	65	4	067101d070cfaf84c7d16c6e517f8946690ad502
ToppCell	Sepsis-ICU-SEP-Lymphocyte-B-B_memory\|ICU-SEP / Disease, condition lineage and cell class	TCF4 IGHG2 GLRA3 SYNPO	2.00e-04	198	65	4	4ba2eb32889bbf043f4bbb822e08eb45a2b576ef
Drug	2-(aminomethyl)pyrrolidine	PLCZ1 GRK2 RNF19A ATP2B2 ATP2B3 ADCY2 ATP2B4	3.44e-07	161	64	7	CID000072032
Drug	mV GABA	GLRA1 GLRA3 MED12	4.21e-07	6	64	3	CID000128435
Drug	1sqc	ATP2B2 ATP2B3 ATP2B4	2.51e-06	10	64	3	CID000444279
Drug	2,5-dimethylquinone	ATP2B2 ATP2B3 ATP2B4	3.44e-06	11	64	3	CID000008718
Drug	1vyq	ATP2B2 ATP2B3 ATP2B4	4.58e-06	12	64	3	CID004369390
Drug	Ro 46861	ATP2B2 ATP2B3 ATP2B4	4.58e-06	12	64	3	CID000003128
Drug	calmidazolium chloride	GRK2 TRPC5 ATP2B2 ATP2B3 ADCY2 ATP2B4	5.87e-06	160	64	6	CID000002531
Drug	8-hydroxycoumarin	ATP2B2 ATP2B3 ATP2B4	5.94e-06	13	64	3	CID000122783
Drug	p-hydroxyhippuric acid	ATP2B2 ATP2B3 ATP2B4	7.54e-06	14	64	3	CID000151012
Drug	AC1L1G0K	UGT1A1 ATP2B2 ATP2B3 ATP2B4	1.09e-05	49	64	4	CID000003473
Drug	AC1L88YH	ATP2B2 ATP2B3 ATP2B4	1.40e-05	17	64	3	CID000374551
Drug	Nabumetone [42924-53-8]; Down 200; 17.6uM; MCF7; HT_HG-U133A	VPS13D PLXNC1 GLRA1 SYBU KLF2 PSD4	1.81e-05	195	64	6	5428_DN
Drug	Isoetharine mesylate salt [7279-75-6]; Down 200; 12uM; PC3; HT_HG-U133A	VPS13D SOCS5 N4BP1 AKAP1 MED12 KLF2	1.87e-05	196	64	6	5812_DN
Drug	Gliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	VPS13D THADA SOCS5 FSD1 N4BP1 ATP2B4	1.92e-05	197	64	6	5514_DN
Drug	Diazoxide [364-98-7]; Down 200; 17.4uM; PC3; HT_HG-U133A	GRK2 RNF19A GLE1 N4BP1 CAMTA2 MED12	1.92e-05	197	64	6	5810_DN
Drug	Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A	THADA GLE1 FSD1 MED12 NPLOC4 MMACHC	2.03e-05	199	64	6	5353_DN
Drug	estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A	TCF4 SYBU AKAP1 DAGLA ATP2B4 PSD4	2.09e-05	200	64	6	5601_UP
Drug	UTP-NA	PLCZ1 GRK2 GYS2 TRPC5 ATP2B2 ATP2B3 ADCY2 ATP2B4	2.25e-05	420	64	8	CID000001181
Drug	2brh	ATP2B2 ATP2B3 ATP2B4	2.72e-05	21	64	3	CID000848641
Drug	halothane	PLCZ1 GLRA1 GLRA3 ATP2B2 ATP2B3 ADCY2 ATP2B4	2.81e-05	314	64	7	CID000003562
Drug	trifluoperazine	UGT1A1 GRK2 GYS2 ATP2B2 ATP2B3 ADCY2 ATP2B4	3.43e-05	324	64	7	CID000005566
Drug	AC1L25Y6	ATP2B2 ATP2B3 ATP2B4	3.60e-05	23	64	3	CID000015465
Drug	lanthanum chloride hydrate	ATP2B2 ATP2B3 ATP2B4	3.60e-05	23	64	3	CID000165791
Drug	lanthanum	TRPC5 ATP2B2 ATP2B3 ADCY2 ATP2B4	4.06e-05	136	64	5	CID000023926
Drug	AC1L1KS5	PLCZ1 GRK2 TRPC5 ATP2B2 DAGLA ATP2B3 ATP2B4	4.16e-05	334	64	7	CID000005631
Drug	iso-THAZ	GLRA1 GLRA3	4.65e-05	4	64	2	CID003047783
Drug	protostrychnine	GLRA1 GLRA3	4.65e-05	4	64	2	CID005320746
Drug	7-nitroindoline	GLRA1 GLRA3	4.65e-05	4	64	2	CID013566747
Drug	2-(phosphonomethyl)phenylalanine	GLRA1 GLRA3	4.65e-05	4	64	2	CID000383689
Drug	SC-49648	GLRA1 GLRA3	4.65e-05	4	64	2	CID000195696
Drug	akuammiline	GLRA1 GLRA3	4.65e-05	4	64	2	CID005367018
Drug	NSC381080	GLRA1 GLRA3	4.65e-05	4	64	2	CID000165497
Drug	N-methyl-THIP	GLRA1 GLRA3	4.65e-05	4	64	2	CID000134373
Drug	SC-48981	GLRA1 GLRA3	4.65e-05	4	64	2	CID000126573
Drug	SC-50132	GLRA1 GLRA3	4.65e-05	4	64	2	CID000195719
Drug	SR 42641	GLRA1 GLRA3	4.65e-05	4	64	2	CID000129049
Drug	cyhexatin	ATP2B2 ATP2B3 ATP2B4	4.66e-05	25	64	3	CID005364545
Drug	TBHQ	UGT1A1 ATP2B2 ATP2B3 ATP2B4 KLF2	4.82e-05	141	64	5	CID000016043
Drug	dodecyl ether	ATP2B2 ATP2B3 ATP2B4	5.26e-05	26	64	3	CID000020667
Drug	milrinone	PLCZ1 GRK2 ATP2B2 ATP2B3 ATP2B4	6.47e-05	150	64	5	CID000004197
Drug	DCCD	GRK2 ATP2B2 ATP2B3 ADCY2 ATP2B4	6.68e-05	151	64	5	CID000010868
Drug	octaethylene glycol	ATP2B2 ATP2B3 ATP2B4	7.35e-05	29	64	3	CID000078798
Drug	azetidine-3-carboxylic acid	GLRA1 GLRA3	7.74e-05	5	64	2	CID000093192
Drug	Lindane	GLRA1 GLRA3	7.74e-05	5	64	2	DB00431
Drug	Cao C	GLRA1 GLRA3	7.74e-05	5	64	2	CID000166617
Drug	oxanilide	GLRA1 GLRA3	7.74e-05	5	64	2	CID000069288
Drug	iso-THAO	GLRA1 GLRA3	7.74e-05	5	64	2	CID000127199
Drug	ALX1393	GLRA1 GLRA3	7.74e-05	5	64	2	CID016078939
Drug	pleiocarpamine	GLRA1 GLRA3	7.74e-05	5	64	2	CID000558637
Drug	mafoprazine	GLRA1 GLRA3	7.74e-05	5	64	2	CID000071241
Drug	gevotroline	GLRA1 GLRA3	7.74e-05	5	64	2	CID000060546
Drug	myo-inositol	PLCZ1 TCF4 GRK2 GLE1 INO80 ATP2B2 DAGLA ATP2B3 ADCY2 ATP2B4	8.25e-05	811	64	10	CID000000892
Drug	XeC compound	TRPC5 ATP2B2 ATP2B3 ATP2B4	9.25e-05	84	64	4	CID000005701
Drug	indole-2-carboxylic acid	UGT1A1 GLRA1 GLRA3	9.91e-05	32	64	3	CID000072899
Drug	xenon	ENAH ATP2B2 ATP2B3 ATP2B4	1.11e-04	88	64	4	CID000023991
Drug	THAZ	GLRA1 GLRA3	1.16e-04	6	64	2	CID000171289
Drug	caged glycine	GLRA1 GLRA3	1.16e-04	6	64	2	CID000192642
Drug	brometone	GLRA1 GLRA3	1.16e-04	6	64	2	CID000006424
Drug	minaxolone	GLRA1 GLRA3	1.16e-04	6	64	2	CID000071960
Drug	thiomuscimol	GLRA1 GLRA3	1.16e-04	6	64	2	CID000005448
Drug	thio-THIP	GLRA1 GLRA3	1.16e-04	6	64	2	CID000656720
Drug	AC1L90PQ	GLRA1 GLRA3	1.16e-04	6	64	2	CID000436036
Drug	fluorescamine	ATP2B2 ATP2B3 ATP2B4	1.30e-04	35	64	3	CID000037927
Drug	mag-fura-2	ATP2B2 ATP2B3 ATP2B4	1.54e-04	37	64	3	CID000123839
Drug	gramicidin s	ATP2B2 ATP2B3 ATP2B4	1.54e-04	37	64	3	CID000073357
Drug	alpha-EMTBL	GLRA1 GLRA3	1.62e-04	7	64	2	CID000128423
Drug	CID189778	GLRA1 GLRA3	1.62e-04	7	64	2	CID000189778
Drug	propyl methanethiosulfonate	GLRA1 GLRA3	1.62e-04	7	64	2	CID000529387
Drug	thiocolchicoside	GLRA1 GLRA3	1.62e-04	7	64	2	CID000072067
Drug	L-serinamide	GLRA1 GLRA3	1.62e-04	7	64	2	CID000101138
Drug	Boc-glycine	GLRA1 GLRA3	1.62e-04	7	64	2	CID000078288
Drug	PK 8165	GLRA1 GLRA3	1.62e-04	7	64	2	CID000071219
Drug	carbidine	ATP2B2 ATP2B3 ATP2B4	1.94e-04	40	64	3	CID000065684
Drug	1-alpha-25-dihydroxycholecalciferol	PLCZ1 TINAG TCF12 RNF19A CAMTA2 SYBU ATP2B2 ATP2B3 FGF19 ATP2B4	2.10e-04	909	64	10	CID000002524
Drug	Zaprinast [37762-06-4]; Down 200; 14.8uM; PC3; HT_HG-U133A	VPS13D GLE1 FSD1 ATP2B2 PSD4	2.11e-04	193	64	5	6749_DN
Drug	WT702	GLRA1 GLRA3	2.15e-04	8	64	2	CID000089643
Drug	isostrychnine	GLRA1 GLRA3	2.15e-04	8	64	2	CID000264626
Drug	sevoflurane	PLCZ1 GLRA1 GLRA3 SH3BP5	2.19e-04	105	64	4	CID000005206
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A	VPS13D GRK2 GLE1 CAMTA2 PSD4	2.22e-04	195	64	5	2317_DN
Drug	Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; HL60; HG-U133A	TCF4 VPS13D BBX N4BP1 ATP2B4	2.22e-04	195	64	5	1575_UP
Drug	C12E8	ATP2B2 ATP2B3 ATP2B4	2.25e-04	42	64	3	CID000123921
Drug	Enoxacin [74011-58-8]; Down 200; 12.4uM; HL60; HG-U133A	TCF4 VPS13D GRK2 GLE1 N4BP1	2.27e-04	196	64	5	1597_DN
Drug	Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A	VPS13D GRK2 FSD1 ATP2B4 ZNF292	2.27e-04	196	64	5	2856_DN
Drug	Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; HL60; HG-U133A	TCF4 BBX N4BP1 FRMD4B ZNF292	2.27e-04	196	64	5	1423_DN
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; HL60; HG-U133A	TCF4 VPS13D THADA GRK2 UBE3C	2.27e-04	196	64	5	1716_DN
Drug	Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A	TCF4 SLC26A4 N4BP1 AKAP1 ADCY2	2.27e-04	196	64	5	4372_UP
Drug	Proglumide [6620-60-6]; Down 200; 12uM; HL60; HT_HG-U133A	RNF19A INTS15 AKAP1 SH3BP5 PSD4	2.32e-04	197	64	5	2363_DN
Drug	Pheniramine maleate [132-20-7]; Down 200; 11.2uM; HL60; HG-U133A	GRK2 GLE1 INTS15 AKAP1 NPLOC4	2.32e-04	197	64	5	1992_DN
Drug	Betulin [473-98-3]; Up 200; 9uM; MCF7; HT_HG-U133A	VPS13D PLXNC1 GLE1 SYBU ATP2B4	2.32e-04	197	64	5	3513_UP
Drug	Meglumine [6284-40-8]; Down 200; 20.4uM; HL60; HT_HG-U133A	TCF4 VPS13D MRTFB PLXNC1 INTS15	2.32e-04	197	64	5	3068_DN
Drug	Muramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; HL60; HT_HG-U133A	TCF4 GRK2 RNF19A FRMD4B PSD4	2.38e-04	198	64	5	1326_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; PC3; HT_HG-U133A	RNF19A FSD1 N4BP1 AKAP1 MMACHC	2.38e-04	198	64	5	5813_DN
Drug	linopirdine	ATP2B2 ATP2B3 ATP2B4	2.41e-04	43	64	3	CID000003932
Drug	GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; PC3; HT_HG-U133A	TCF4 VPS13D ATP2B2 DAGLA PSD4	2.43e-04	199	64	5	4641_DN
Drug	Tetrandrine [518-34-3]; Down 200; 6.4uM; PC3; HT_HG-U133A	TCF4 VPS13D GRK2 N4BP1 MED12	2.43e-04	199	64	5	5821_DN
Drug	Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; HL60; HG-U133A	VPS13D THADA VPS13C SOCS5 N4BP1	2.43e-04	199	64	5	1727_DN
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	VPS13D GRK2 N4BP1 FRMD4B KLF2	2.43e-04	199	64	5	4687_UP
Drug	Methotrexate [59-05-2]; Up 200; 8.8uM; PC3; HG-U133A	VPS13D SURF2 FSD1 MED12 MMACHC	2.43e-04	199	64	5	1957_UP
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	TCF4 VPS13D GRK2 SYNPO DAGLA	2.43e-04	199	64	5	6361_DN
Drug	Trolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A	GRK2 SOCS5 SYBU ATP2B4 ZNF292	2.43e-04	199	64	5	2883_DN
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B3 ATP2B4	1.76e-07	6	62	3	DOID:0050429 (implicated_via_orthology)
Disease	alopecia	TCF4 THADA TCF12 BBX AKAP1 BIRC6	1.17e-05	241	62	6	MONDO_0004907
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13D VPS13C	1.30e-05	3	62	2	DOID:0111611 (implicated_via_orthology)
Disease	Pitt-Hopkins syndrome (implicated_via_orthology)	TCF4 TCF12	1.30e-05	3	62	2	DOID:0060488 (implicated_via_orthology)
Disease	carbohydrate measurement	TINAG ATP2B2 ATP2B4	1.26e-04	46	62	3	EFO_0004998
Disease	bipolar I disorder	TDRD15 ATP2B2 ADCY2 ATP2B4	2.25e-04	141	62	4	EFO_0009963
Disease	unipolar depression, multiple sclerosis	TDRD15 BBX	2.83e-04	12	62	2	EFO_0003761, MONDO_0005301
Disease	aggressive behaviour measurement, ADHD symptom measurement	TCF4 BBX BIRC6	4.02e-04	68	62	3	EFO_0007826, EFO_0007860
Disease	creatinine measurement	TCF4 TCF12 PLXNC1 INO80 BIRC6 ADCY2 NPLOC4 PSD4	1.10e-03	995	62	8	EFO_0004518
Disease	obesity (implicated_via_orthology)	TCF4 THADA TCF12 MED12	1.10e-03	215	62	4	DOID:9970 (implicated_via_orthology)
Disease	Myopia	CNTNAP5 ENAH UBE3C FRMD4B NPLOC4	1.30e-03	385	62	5	HP_0000545
Disease	interleukin-6 measurement	ENAH ATP2B2 ATP2B4	1.71e-03	112	62	3	EFO_0004810
Disease	progressive supranuclear palsy	ATP2B2 ATP2B4	1.94e-03	31	62	2	MONDO_0019037
Disease	cysteine-rich with EGF-like domain protein 1 measurement	ATP2B2 ATP2B4	2.07e-03	32	62	2	EFO_0021870

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDSVMPLSDDDQFSP	AKAP1	826	Q92667
SPFDPVLFDLEMSGS	BIRC6	1501	Q9NR09
STPEMPAVSAFFSLA	BBX	886	Q8WY36
FSMPSVPDFETLFSQ	COPS3	66	Q9UNS2
SLDLPSPVSLSEFGM	SH3BP5	346	O60239
FLSSTSPLLPMDYEE	GYS2	481	P54840
PTFLPTEDSDFLMSL	FBXO10	281	Q9UK96
SELEPFSLSSFPDLM	CAMTA2	496	O94983
MEPLSDVTATLLFDF	GLE1	611	Q53GS7
FDSLSPEPKSRFAML	ANGPTL3	26	Q9Y5C1
IMDTFASLALATEPP	ATP2B2	916	Q01814
MDTFASLALATEPPT	ATP2B3	891	Q16720
IMDTFASLALATEPP	ATP2B4	881	P23634
TLTMAVELPDSFSPE	GRK2	406	P25098
YPDDSLDLDPSMLDS	GLRA3	111	O75311
FISVDSAMPSPFSEI	INO80	1346	Q9ULG1
TALYDLSSDDLIPPM	INTS15	186	Q96N11
MPAASKSSSDAFFLP	M1AP	506	Q8TC57
SFDGSPSPEAEMLKF	INMT	26	O95050
DLDSSTASFDPPSDM	GOLGA4	106	Q13439
EFSEPVTLETPAFMF	FSD1	256	Q9BTV5
LSDLLDFSAMFSPPV	TCF4	16	P15884
DLPPLSSSEMEEFLT	PLXNC1	1491	O60486
FLFPSSLAGPSSEME	NPLOC4	76	Q8TAT6
DMFSSPLETDSMDPF	FGF19	186	O95750
ELSDLLDFSAMFSPP	TCF12	16	Q99081
STTAPSMFSADFLDP	MRTFB	1066	Q9ULH7
SMFSADFLDPQDLPL	MRTFB	1071	Q9ULH7
FEDMEKPDFSLFSPT	MED12	676	Q93074
PTLAFLVLSTPAMFD	MMACHC	46	Q9Y4U1
PDAADSATFMLPAAS	PKD1L2	1086	Q7Z442
LLSEMDSDKPFFSLS	FRMD4B	701	Q9Y2L6
FNMFFLSDSEETIPP	ADCY2	696	Q08462
AETFPLMSPLEDLSL	CMYA5	1066	Q8N3K9
LLMPPDALTDTDFQS	TMEM63B	806	Q5T3F8
PLSPMTASSFLSFAE	FEM1A	426	Q9BSK4
SFPLSSSGELMDLTP	DAGLA	991	Q9Y4D2
KTTPPMLDSDGSFFL	IGHG2	271	P01859
PLPASGFFLASMSED	ENAH	371	Q8N8S7
DDPLASLLSPMAFSS	CNTNAP5	31	Q8WYK1
SSLNSLPDFFLPEAM	THADA	101	Q6YHU6
TTSMLDFSNPSDIPD	RAPGEF6	736	Q8TEU7
DPSSCMFFEPLLTIS	SOCS5	461	O75159
MDSTSFLPTFLDVDL	TDRD15	1	B5MCY1
SLLSDMLDDFPDTLP	PLCZ1	271	Q86YW0
PPASDFMSSSLLIDI	SYNPO	426	Q8N3V7
YPDDSLDLDPSMLDS	GLRA1	106	P23415
EESMFFSNPLFLASP	PSD4	241	Q8NDX1
AASDDSMTDLYPPEL	SURF2	161	Q15527
FIFTSSEIADPEMPL	B3GALT9	306	A8MXE2
FSDPSDTALLNLLPM	CTDNEP1	206	O95476
TFISFPLELDMTPFL	USP51	611	Q70EK9
SEFEAPSLSDSMPSV	RNF19A	706	Q9NV58
AFPDIMFSRATSLPD	SPATA46	21	Q5T0L3
PPVSLFSEMLAASFS	SLC26A4	341	O43511
PDSMESFPESLSALV	SYBU	526	Q9NX95
ALLDLSFAYMPPTSE	TAPBP	176	O15533
AESSFDVMLTDPFLP	UGT1A1	141	P22309
PFLPLPAESSSMSLF	ZNF292	1261	O60281
NDIFFTEPTPEMSSL	nan	11	Q8N8P6
MDFLSSAAPFSEPSS	VPS13C	1551	Q709C8
FSEFTPDITPIMLAA	TRPC5	136	Q9UL62
EMTASLPATTDLPEF	TINAG	206	Q9UJW2
SPMSFEDSSRIIPLF	UBE3C	486	Q15386
DLSPQPLMTDFERSF	VPS13D	1136	Q5THJ4
MALSEPILPSFSTFA	KLF2	1	Q9Y5W3
MDTVLSSSPDVLFDP	N4BP1	251	O75113