Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction5-methylcytosine dioxygenase activity

TET1 TET3

1.92e-053512GO:0070579
GeneOntologyCellularComponentsupramolecular fiber

DLGAP2 MYL1 AHNAK STAU2 KIF4A COBL KIF4B SKA1 DYNC1I2 RYR3

3.43e-0411794910GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

DLGAP2 MYL1 AHNAK STAU2 KIF4A COBL KIF4B SKA1 DYNC1I2 RYR3

3.62e-0411874910GO:0099081
HumanPhenoHyperactivity

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

4.45e-065581810HP:0000752
HumanPhenoShort attention span

PIEZO2 CHD5 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

2.24e-05517189HP:0000736
HumanPhenoReduced attention regulation

PIEZO2 CHD5 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

2.58e-05526189HP:5200044
HumanPhenoAttention deficit hyperactivity disorder

PIEZO2 CHD5 PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

3.69e-05413188HP:0007018
HumanPhenoAbnormal response to social norms

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

1.22e-048071810HP:5200123
HumanPhenoSocial disinhibition

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

1.22e-048071810HP:5200029
HumanPhenoDisinhibition

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

1.22e-048071810HP:0000734
HumanPhenoInappropriate behavior

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

1.22e-048071810HP:0000719
HumanPhenoMotor delay

PIEZO2 MYL1 CHD5 KMT2A CHD7 TET3 MED13 PRX DYNC1I2 KDM4B RYR3

1.53e-0410181811HP:0001270
HumanPhenoAbnormally increased volition

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

2.32e-048691810HP:5200263
HumanPhenoAbnormal social development

PIEZO2 CHD5 GLRA2 KMT2A PDZD8 CHD7 TET3 MED13 DYNC1I2 KDM4B

3.38e-049081810HP:0025732
MousePhenoabnormal hippocampus size

KIF4A PDZD8 KIF4B CHD7

1.59e-0555394MP:0008281
MousePhenoincreased dendritic spine number

KIF4A KIF4B

2.27e-053392MP:0021019
MousePhenoabnormal limbic system morphology

CHL1 TET1 KIF4A PDZD8 KIF4B CHD7 KDM4B

7.29e-05378397MP:0004166
MousePhenoabnormal retrosplenial region morphology

PDZD8 CHD7

1.58e-047392MP:0012489
MousePhenobehavioral developmental delay

KIF4A KIF4B

2.10e-048392MP:0021165
MousePhenosmall hippocampus

KIF4A KIF4B CHD7

2.80e-0446393MP:0008283
MousePhenoabnormal hippocampus morphology

CHL1 KIF4A PDZD8 KIF4B CHD7 KDM4B

2.84e-04331396MP:0000807
MousePhenoabnormal dendritic spine morphology

DLGAP2 ARHGAP44 KIF4A KIF4B

2.86e-04115394MP:0009936
MousePhenoabnormal temporal lobe morphology

CHL1 KIF4A PDZD8 KIF4B CHD7 KDM4B

3.13e-04337396MP:0000801
MousePhenoabnormal dendritic spine number

KIF4A KIF4B

3.37e-0410392MP:0021017
MousePhenoabnormal cingulate gyrus morphology

PDZD8 CHD7

3.37e-0410392MP:0004167
DomainZnf_CXXC

TET1 KMT2A

3.65e-0411492IPR002857
DomainZF_CXXC

TET1 KMT2A

3.65e-0411492PS51058
Domainzf-CXXC

TET1 KMT2A

3.65e-0411492PF02008
DomainZnf_FYVE_PHD

CHD5 KMT2A FGD6 KDM4B

5.93e-04147494IPR011011
DomainPHD

CHD5 KMT2A KDM4B

1.00e-0375493PF00628
DomainEPHD

KMT2A KDM4B

1.51e-0322492PS51805
DomainPHD

CHD5 KMT2A KDM4B

1.64e-0389493SM00249
DomainZnf_PHD

CHD5 KMT2A KDM4B

1.75e-0391493IPR001965
DomainChromo_domain

CHD5 CHD7

1.79e-0324492IPR023780
DomainZF_PHD_2

CHD5 KMT2A KDM4B

1.98e-0395493PS50016
DomainZF_PHD_1

CHD5 KMT2A KDM4B

2.04e-0396493PS01359
DomainChromo

CHD5 CHD7

2.11e-0326492PF00385
DomainCHROMO_1

CHD5 CHD7

2.44e-0328492PS00598
DomainCHROMO_2

CHD5 CHD7

2.44e-0328492PS50013
DomainSNF2_N

CHD5 CHD7

3.18e-0332492IPR000330
DomainChromodomain-like

CHD5 CHD7

3.18e-0332492IPR016197
DomainSNF2_N

CHD5 CHD7

3.18e-0332492PF00176
DomainChromo/shadow_dom

CHD5 CHD7

3.38e-0333492IPR000953
DomainCHROMO

CHD5 CHD7

3.38e-0333492SM00298
DomainDNA/RNA_helicase_DEAH_CS

CHD5 CHD7

3.80e-0335492IPR002464
DomainDEAH_ATP_HELICASE

CHD5 CHD7

4.46e-0338492PS00690
DomainARM_REPEAT

ARMC3 ARMCX5

4.94e-0340492PS50176
DomainKinesin_motor_CS

KIF4A KIF4B

5.18e-0341492IPR019821
DomainKinesin-like_fam

KIF4A KIF4B

5.69e-0343492IPR027640
DomainKINESIN_MOTOR_1

KIF4A KIF4B

5.95e-0344492PS00411
Domain-

KIF4A KIF4B

5.95e-03444923.40.850.10
DomainKinesin_motor_dom

KIF4A KIF4B

5.95e-0344492IPR001752
DomainKinesin

KIF4A KIF4B

5.95e-0344492PF00225
DomainKINESIN_MOTOR_2

KIF4A KIF4B

5.95e-0344492PS50067
DomainKISc

KIF4A KIF4B

5.95e-0344492SM00129
DomainPDZ

AHNAK PDZD8 PRX

6.02e-03141493PF00595
Domain-

ZMIZ2 CHD5 KMT2A FGD6 KDM4B

6.28e-034494953.30.40.10
DomainArmadillo

ARMC3 ARMCX5

6.76e-0347492IPR000225
DomainZnf_RING/FYVE/PHD

ZMIZ2 CHD5 KMT2A FGD6 KDM4B

6.88e-03459495IPR013083
DomainPDZ

AHNAK PDZD8 PRX

6.88e-03148493SM00228
Domain-

AHNAK PDZD8 PRX

7.14e-031504932.30.42.10
DomainPDZ

AHNAK PDZD8 PRX

7.27e-03151493PS50106
DomainPDZ

AHNAK PDZD8 PRX

7.41e-03152493IPR001478
DomainSANT

CHD7 DNAJC1

7.62e-0350492SM00717
DomainSANT/Myb

CHD7 DNAJC1

8.22e-0352492IPR001005
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RYBP EME1 TBC1D31 ARMC3 HSPA4L NHSL2 CTR9 AHNAK CHD5 KMT2A MLLT1 LRRC43 MED13 PRX DYNC1I2

1.34e-091442511535575683
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RYBP EME1 EXOSC10 WDR36 RBM27 CTR9 AHNAK KMT2A KIF4A MLLT1 CHD7 DNAJC1 TET3

3.15e-081294511330804502
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

RBM27 HSPA4L AHNAK KMT2A KIF4A CHD7 KRR1 DYNC1I2

1.05e-0739451827248496
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

EXOSC10 RBM27 CTR9 KMT2A KIF4A CHD7 MED13

1.29e-0726851733640491
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

DLGAP2 MYL1 AHNAK KIF4A KIF4B DYNC1I2 RYR3

1.91e-0728451729459677
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

TET1 KMT2A TET3

3.54e-071051329276034
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

EME1 TBC1D31 RBM27 AHNAK KMT2A KIF4A SKA1 MED13 KDM4B

3.73e-0764551925281560
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EXOSC10 WDR36 RBM27 AHNAK STAU2 KMT2A KIF4A MLLT1 CHD7 KRR1

1.06e-06954511036373674
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

WDR36 RBM27 CTR9 FARP1 STAU2 KMT2A KIF4A MLLT1 CHD7 DNAJC1 KRR1 MED13

1.29e-061497511231527615
Pubmed

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.

TET1 KMT2A

2.11e-06251223100278
Pubmed

Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.

KMT2A MLLT1

2.11e-06251219029444
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

2.11e-06251236482480
Pubmed

LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).

TET1 KMT2A

2.11e-06251212124344
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

2.11e-06251221565503
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

2.11e-06251231486502
Pubmed

The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia.

KMT2A MLLT1

2.11e-06251236435883
Pubmed

Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia.

KMT2A MLLT1

2.11e-06251217252016
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

2.11e-06251210773663
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

2.11e-0625127929562
Pubmed

Specificity of MLL1 and TET3 CXXC domains towards naturally occurring cytosine modifications.

KMT2A TET3

2.11e-06251230352306
Pubmed

Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation.

TET1 TET3

2.11e-06251226711116
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

2.11e-06251230081192
Pubmed

Clinical outcome and monitoring of minimal residual disease in patients with acute lymphoblastic leukemia expressing the MLL/ENL fusion gene.

KMT2A MLLT1

2.11e-06251221953510
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

2.11e-06251231616463
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

2.11e-06251223500491
Pubmed

Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk.

BTK MLLT1

2.11e-06251211007757
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

2.11e-06251231067151
Pubmed

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

TET1 TET3

2.11e-06251226703470
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

2.11e-06251228350061
Pubmed

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.

TET1 KMT2A

2.11e-06251219144982
Pubmed

Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.

TET1 TET3

2.11e-06251226294212
Pubmed

Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia.

KMT2A MLLT1

2.11e-0625128378076
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

2.11e-0625129658142
Pubmed

First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia.

TET1 KMT2A

2.11e-06251224323992
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

2.11e-06251210559369
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

2.11e-06251224658398
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

NHSL1 RBM27 CHD5 CHD7 FGD6

3.08e-0615351510718198
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NHSL1 CRYBG2 AHNAK ZMIZ2 CHD5 ARHGAP44 MLLT1 PDZD8 COBL MED13

3.93e-061105511035748872
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RYBP CRYBG2 WDR36 AHNAK KMT2A CHD7 KRR1

5.38e-0646951727634302
Pubmed

Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss.

TET1 TET3

6.32e-06351230074219
Pubmed

Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.

TET1 TET3

6.32e-06351224194590
Pubmed

TET proteins in malignant hematopoiesis.

TET1 TET3

6.32e-06351219923888
Pubmed

A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.

KMT2A MLLT1

6.32e-06351218829457
Pubmed

Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.

KMT2A MLLT1

6.32e-06351218829459
Pubmed

5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.

TET1 TET3

6.32e-06351234919053
Pubmed

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.

TET1 TET3

6.32e-06351224958354
Pubmed

Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.

KIF4A KIF4B

6.32e-06351210978527
Pubmed

Infrequent occurrence of TET1, TET3, and ASXL2 mutations in myelodysplastic/myeloproliferative neoplasms.

TET1 TET3

6.32e-06351229531217
Pubmed

Reduced Expression of TET1, TET2, TET3 and TDG mRNAs Are Associated with Poor Prognosis of Patients with Early Breast Cancer.

TET1 TET3

6.32e-06351226207381
Pubmed

Selective targeting of TET catalytic domain promotes somatic cell reprogramming.

TET1 TET3

6.32e-06351232024762
Pubmed

Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs.

TET1 TET3

6.32e-06351227184841
Pubmed

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.

TET1 TET3

6.32e-06351223643243
Pubmed

KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.

KIF4A KIF4B

6.32e-06351216630823
Pubmed

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.

TET1 TET3

6.32e-06351221778364
Pubmed

Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation.

TET1 TET3

6.32e-06351234879277
Pubmed

Tet family proteins and 5-hydroxymethylcytosine in development and disease.

TET1 TET3

6.32e-06351222569552
Pubmed

Oxygen regulation of TET enzymes.

TET1 TET3

6.32e-06351233410283
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK PRX

6.32e-06351221940993
Pubmed

Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.

TET1 TET3

6.32e-06351222445327
Pubmed

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

TET1 TET3

6.32e-06351219372391
Pubmed

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

TET1 KMT2A

6.32e-06351212646957
Pubmed

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.

TET1 TET3

6.32e-06351224735881
Pubmed

Differential expression of ten-eleven translocation genes in endometrial cancers.

TET1 TET3

6.32e-06351228349832
Pubmed

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer.

KMT2A MLLT1

6.32e-06351212781363
Pubmed

Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.

KMT2A MLLT1

6.32e-06351210995463
Pubmed

CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.

KIF4A KIF4B

6.32e-06351235579738
Pubmed

Tumor formation via loss of a molecular motor protein.

KIF4A KIF4B

6.32e-06351216890532
Pubmed

Three-way translocation involving MLL, MLLT1, and a novel third partner, NRXN1, in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12;p13.3;q23).

KMT2A MLLT1

6.32e-06351220113834
Pubmed

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.

TET1 TET3

6.32e-06351220639862
Pubmed

Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited.

KMT2A MLLT1

6.32e-06351216433901
Pubmed

Ten-Eleven Translocation Genes are Downregulated in Endometriosis.

TET1 TET3

6.32e-06351226917261
Pubmed

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias.

KMT2A MLLT1

6.32e-0635121423624
Pubmed

Mechanisms of TET protein-mediated DNA demethylation and its role in the regulation of mouse development.

TET1 TET3

6.32e-06351225608811
Pubmed

KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.

KIF4A KIF4B

6.32e-06351219158085
Pubmed

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.

TET1 TET3

6.32e-06351219420352
Pubmed

Alternation of ten-eleven translocation 1, 2, and 3 expression in eutopic endometrium of women with endometriosis-associated infertility.

TET1 TET3

6.32e-06351230130982
Pubmed

Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation.

TET1 TET3

6.32e-06351228218476
Pubmed

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

TET1 TET3

6.32e-06351223548903
Pubmed

Regulation of DNA methylation signatures on NF-κB and STAT3 pathway genes and TET activity in cigarette smoke extract-challenged cells/COPD exacerbation model in vitro.

TET1 TET3

6.32e-06351232342329
Pubmed

TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro.

TET1 TET3

1.26e-05451233134768
Pubmed

Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.

TET1 TET3

1.26e-05451235235365
Pubmed

Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.

KIF4A KIF4B

1.26e-05451218684836
Pubmed

Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the O-linked N-acetylglucosamine transferase (OGT).

TET1 TET3

1.26e-05451225568311
Pubmed

Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation.

KMT2A MLLT1

1.26e-05451225456127
Pubmed

Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.

TET1 KMT2A

1.26e-05451226791235
Pubmed

Kif4 Is Essential for Mouse Oocyte Meiosis.

KIF4A KIF4B

1.26e-05451228125646
Pubmed

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.

TET1 TET3

1.26e-05451221321204
Pubmed

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.

TET1 TET3

1.26e-05451231371502
Pubmed

Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).

TET1 TET3

1.26e-05451224394411
Pubmed

Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.

TET1 TET3

1.26e-05451223028748
Pubmed

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.

TET1 TET3

1.26e-05451230554962
Pubmed

A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors.

TET1 TET3

1.26e-05451225089631
Pubmed

Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis.

KMT2A MLLT1

1.26e-05451216096649
Pubmed

The intrinsic and extrinsic effects of TET proteins during gastrulation.

TET1 TET3

1.26e-05451235908548
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

WDR36 RBM27 HSPA4L CTR9 AHNAK BTK STAU2 KMT2A CHD7 KRR1

1.83e-051318511030463901
Pubmed

CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.

TET1 TET3

2.10e-05551235304452
Pubmed

DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation.

TET1 TET3

2.10e-05551236880575
Pubmed

Lineage-specific functions of TET1 in the postimplantation mouse embryo.

TET1 TET3

2.10e-05551228504700
Pubmed

The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development.

KMT2A MLLT1

2.10e-05551231405949
Pubmed

Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression.

TET1 TET3

2.10e-05551235737830
Cytoband10p12.31

ARMC3 DNAJC1

2.76e-042251210p12.31
CytobandXq13.1

NHSL2 KIF4A

1.32e-0348512Xq13.1
GeneFamilyZinc fingers CXXC-type

TET1 KMT2A TET3

1.71e-0612373136
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ARMC3 ARMCX5

3.49e-0343372409
GeneFamilyPDZ domain containing

AHNAK PDZD8 PRX

3.67e-031523731220
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF4A KIF4B

3.99e-0346372622
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

CHD7 DNAJC1

5.26e-0353372532
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FARP1 FGD6

8.05e-0366372722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FARP1 BTK FGD6

8.52e-03206373682
GeneFamilyPHD finger proteins

CHD5 KMT2A

1.46e-029037288
GeneFamilyWD repeat domain containing

TBC1D31 WDR36 DYNC1I2

1.63e-02262373362
CoexpressionGSE27786_CD8_TCELL_VS_MONO_MAC_DN

EME1 MYL1 TBC1D31 HSPA4L FARP1 PDZD8

2.48e-06200516M4849
CoexpressionGSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

DLGAP2 EME1 CHD5 COBL DEPDC1B

4.14e-05198515M6213
CoexpressionGSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP

DLGAP2 EME1 FARP1 COBL DEPDC1B

4.14e-05198515M6232
CoexpressionGSE13493_DP_VS_CD8POS_THYMOCYTE_UP

CHL1 HSPA4L BTK FYB1 MED13

4.24e-05199515M3314
CoexpressionAtlasB cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Fetal Liver, avg-1

EME1 TBC1D31 CTR9 BTK TET1 KIF4A DEPDC1B

5.57e-05422507GSM538357_500
CoexpressionAtlasB cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R+ CD, Fetal Liver, avg-2

EME1 TBC1D31 CTR9 BTK TET1 KIF4A DEPDC1B

5.57e-05422507GSM538355_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

EME1 CHD7 DNAJC1 SKA1 FGD6

8.74e-05192505Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

EME1 EXOSC10 TBC1D31 KIF4A SKA1 DEPDC1B

6.45e-08183516f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 GLRA2 KIF4A SKA1 DEPDC1B

1.00e-061575151ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EME1 TBC1D31 KIF4A SKA1 DEPDC1B

1.71e-061755156751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 BTK KIF4A SKA1 DEPDC1B

2.07e-06182515bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 BTK KIF4A SKA1 DEPDC1B

2.07e-061825150fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 TBC1D31 KIF4A SKA1 DEPDC1B

2.30e-061865159feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 TBC1D31 KIF4A SKA1 DEPDC1B

2.30e-0618651589f5b06bc56674af304912d481ac697c7c870904
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative|Multiple_Sclerosis / Disease, Lineage and Cell Type

EME1 KIF4A KIF4B SKA1 DEPDC1B

2.43e-061885156c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

EME1 KIF4A KIF4B SKA1 DEPDC1B

2.56e-06190515005967c540418b85311308072a07c684f4296aef
ToppCelldistal-Hematologic-Proliferating_NK/T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EME1 KIF4A KIF4B SKA1 DEPDC1B

3.05e-0619751504b10879e48c101d1de449db0bc6b6484090b965
ToppCelldistal-1-Hematologic-EREG+_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR36 NHSL2 KIF4A FYB1 DEPDC1B

3.21e-0619951515249f2f48b1e99d9d062835fd4c705a159e4abb
ToppCelldistal-Hematologic-EREG+_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR36 NHSL2 KIF4A FYB1 DEPDC1B

3.28e-062005157809c74a2e52768854b66a135522138281bc4449
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Hist1h2al)|Hippocampus / BrainAtlas - Mouse McCarroll V32

EME1 KIF4A SKA1 DEPDC1B

1.32e-051265146072996987f7b05949adb86c9433e3302c4441d2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CHL1 DLGAP2 HSPA4L CHD5

1.32e-05126514ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EME1 KIF4A SKA1 DEPDC1B

2.84e-05153514d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EME1 KIF4A SKA1 DEPDC1B

2.84e-0515351454a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EME1 KIF4A SKA1 DEPDC1B

2.84e-0515351469a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EME1 KIF4A SKA1 DEPDC1B

2.84e-05153514e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

3.06e-05156514955547dfeb1b1ad4957b4338701055726b22619f
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EME1 GGA2 BTK FGD6

3.06e-05156514203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NHSL1 MYL1 BTK FYB1

3.14e-051575148c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NHSL1 MYL1 BTK FYB1

3.14e-05157514ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NHSL1 MYL1 BTK FYB1

3.14e-05157514008f938a338f43c3251dcac574f1b4f689926c71
ToppCellIIF-Lymphocyte-B-Plasmablast|IIF / Disease, Lineage and Cell Type

EME1 KIF4B SKA1 DEPDC1B

3.46e-051615144d78985e7b11e92591e75a4864fd769882db2d1c
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBC1D31 KIF4A SKA1 DEPDC1B

3.63e-051635145285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF4A SKA1 DEPDC1B RYR3

3.72e-051645144307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EME1 KIF4A SKA1 DEPDC1B

3.72e-05164514ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF4A SKA1 DEPDC1B RYR3

3.72e-051645141d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PROCA1 KIF4A SKA1 DEPDC1B

3.90e-05166514c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EME1 KIF4A SKA1 FYB1

3.99e-05167514d21635df8b74189e3309eaf435af381fbe412574
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

EME1 KIF4A SKA1 DEPDC1B

4.28e-051705145319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EME1 CHD5 KIF4A SKA1

4.48e-051725141171e754fd503a0c1152162fcc12a115088a08c7
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 PIEZO2 KIF4A SKA1

4.58e-05173514f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 KIF4A COBL DEPDC1B

4.79e-05175514cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell10x_5'_v1-Neoplastic-Stem-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 KIF4A COBL DEPDC1B

4.79e-05175514a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 KIF4A COBL DEPDC1B

4.79e-051755148a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 KIF4A COBL DEPDC1B

4.79e-05175514378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EME1 KIF4A SKA1 DEPDC1B

4.90e-051765148813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

EME1 KIF4A SKA1 DEPDC1B

4.90e-05176514a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell(01)_Cycling_Basal_(homeostasis)|World / shred by cell type and Timepoint

EME1 KIF4A SKA1 DEPDC1B

5.01e-0517751405c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

EME1 KIF4A SKA1 DEPDC1B

5.23e-051795149383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

EME1 KIF4A SKA1 DEPDC1B

5.23e-05179514e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

5.23e-0517951480112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

5.35e-05180514401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EME1 TBC1D31 KIF4A DEPDC1B

5.35e-05180514334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

5.35e-05180514f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBC1D31 KIF4A SKA1 DEPDC1B

5.46e-05181514e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBC1D31 KIF4A SKA1 DEPDC1B

5.46e-051815142be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PROCA1 KIF4A SKA1 DEPDC1B

5.46e-0518151473b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL2 KIF4A SKA1 DEPDC1B

5.46e-05181514566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL2 KIF4A SKA1 DEPDC1B

5.46e-05181514db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

5.58e-05182514336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

KIF4A KIF4B SKA1 DEPDC1B

5.95e-051855140ae9c646679c69a553eda670aef0e0495feb0286
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

5.95e-0518551430e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

6.20e-051875149351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EME1 KIF4A SKA1 DEPDC1B

6.20e-05187514057569c9437219ecc396aa6e673b1178a2273837
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EME1 KIF4A SKA1 DEPDC1B

6.33e-051885140ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCelldroplet-Fat-SCAT-30m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL1 AHNAK COBL PRX

6.46e-051895148161910a19089f8cc5a3f1fda039f41a2488f04f
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 KIF4A SKA1 DEPDC1B

6.46e-05189514bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 KIF4A SKA1 DEPDC1B

6.46e-0518951496f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellDividing_Macrophages-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

EME1 KIF4A SKA1 DEPDC1B

6.46e-05189514d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCelldroplet-Fat-SCAT|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL1 AHNAK COBL PRX

6.46e-05189514264c59de2adb8bee5bb57633d79d530a8829617b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF4A COBL SKA1 DEPDC1B

6.59e-05190514b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellnormal_Pleural_Fluid-T/NK_cells-Undetermined|normal_Pleural_Fluid / Location, Cell class and cell subclass

KIF4A KIF4B SKA1 DEPDC1B

6.59e-05190514165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBC1D31 KIF4A SKA1 DEPDC1B

6.73e-051915140ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell(3)_Macrophage_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

KIF4A KIF4B SKA1 DEPDC1B

6.73e-05191514b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TBC1D31 KIF4A SKA1 DEPDC1B

6.87e-0519251427723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EME1 TBC1D31 KIF4A SKA1

6.87e-0519251496f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TBC1D31 KIF4A SKA1 DEPDC1B

6.87e-05192514026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EME1 KIF4A SKA1 DEPDC1B

7.01e-05193514e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF4A SKA1 FYB1 DEPDC1B

7.01e-05193514b835d28de9daeec5213172c96f62b332cda53bb5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EME1 KIF4A SKA1 DEPDC1B

7.15e-05194514f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EME1 KIF4A SKA1 DEPDC1B

7.15e-0519451417af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EME1 KIF4A SKA1 DEPDC1B

7.15e-051945143c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EME1 KIF4A SKA1 DEPDC1B

7.15e-051945146cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EME1 KIF4A SKA1 DEPDC1B

7.15e-05194514a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EME1 KIF4A SKA1 DEPDC1B

7.15e-0519451417744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GGA2 KIF4A SKA1 DEPDC1B

7.15e-0519451406b8dc2e46f833707d5b68b324b4ff6c4d0dccf9
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EME1 KIF4A SKA1 DEPDC1B

7.15e-05194514635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

KIF4A KIF4B SKA1 DEPDC1B

7.15e-05194514a12b64945e10f00aa983678a02586c59badc1570
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

EME1 KIF4A SKA1 DEPDC1B

7.15e-05194514e14f66f7584909621b776292fbd52808273fd2ee
ToppCellHealthy-B_intermediate|Healthy / disease group, cell group and cell class

CHL1 GGA2 ARHGAP44 CHD7

7.15e-05194514aabee48bf689367edae2079b4b90d253715f1097
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

EME1 KIF4A SKA1 DEPDC1B

7.29e-0519551479ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

EME1 KIF4A SKA1 DEPDC1B

7.29e-0519551419829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

KIF4A SKA1 FYB1 DEPDC1B

7.29e-051955147e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellInfluenza_Severe-T/NK_proliferative|World / Disease group and Cell class

EME1 KIF4A SKA1 DEPDC1B

7.29e-051955146f079c2d7d08110a5e1822ea861b8037eb3f62c9
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

EME1 KIF4A SKA1 DEPDC1B

7.29e-05195514957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellILEUM-non-inflamed-(1)_Highly_activated_T_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

EME1 KIF4A SKA1 DEPDC1B

7.44e-051965146a415a2574bd84bd825a2bd6c8e3632a433ff7cf
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF4A KIF4B SKA1 DEPDC1B

7.44e-051965149591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

PIEZO2 KIF4A SKA1 DEPDC1B

7.44e-051965142ce8a787f2731faa913d20342d73041d59468f27
ToppCellHealthy-T/NK_proliferative|Healthy / disease group, cell group and cell class

EME1 KIF4A SKA1 DEPDC1B

7.44e-0519651491e44aabb2e85dcc77ddae6f7e000118d45d1de6
ToppCellControl-T/NK_proliferative|Control / Disease condition and Cell class

EME1 KIF4A SKA1 DEPDC1B

7.44e-051965147b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCell(3)_MNP-(3)_Macrophage_Dividing|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

KIF4A KIF4B SKA1 DEPDC1B

7.58e-05197514048bc4f8fd5d4f394e2384700640f72042336597
ToppCellHealthy-T/NK_proliferative|World / disease group, cell group and cell class

EME1 KIF4A SKA1 DEPDC1B

7.58e-05197514e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCellHealthy/Control-T/NK_proliferative|World / Disease group and Cell class

EME1 KIF4A SKA1 DEPDC1B

7.58e-051975144a4d3083938783d6f5b87da02f10e501917da0b4
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EME1 KIF4A SKA1 DEPDC1B

7.58e-051975147eb4c1cffd0366204af7e63adc8f751685601a94
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EME1 KIF4A SKA1 DEPDC1B

7.58e-0519751425bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCellMS-IIF-Lymphocyte-B-Plasmablast|IIF / Disease, condition lineage and cell class

EME1 KIF4A SKA1 DEPDC1B

7.58e-051975141b5ac53297cc557e08b9e8e511c2385a38f56bd6
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(I)|GI_large-bowel / Manually curated celltypes from each tissue

KIF4A SKA1 FGD6 DEPDC1B

7.58e-0519751480a0cfbd454409594effead7082586b06c2f411a
ToppCellHealthy_donor-T/NK_proliferative|Healthy_donor / disease group, cell group and cell class (v2)

EME1 KIF4A SKA1 DEPDC1B

7.58e-05197514b6bbf87e5823fa66b4cad6a7be4f777356887b59
DrugDesipramine hydrochloride [58-28-6]; Up 200; 13.2uM; MCF7; HT_HG-U133A

CRYBG2 ZMIZ2 CHD5 FYB1 FGD6 PRX

4.78e-061955163212_UP
Diseasemonocyte percentage of leukocytes

RYBP CRYBG2 RBM27 AHNAK MLLT1 CHD7 DNAJC1 KDM4B

2.51e-05731498EFO_0007989
DiseaseAutistic behavior

TET3 MED13

7.52e-058492C0856975
Diseaseepilepsy (implicated_via_orthology)

CHL1 KCNK18 KIF4A KIF4B

1.57e-04163494DOID:1826 (implicated_via_orthology)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

MED13 KDM4B

3.62e-0417492DOID:0060307 (is_implicated_in)
DiseaseAutism Spectrum Disorders

GLRA2 TET1 TET3

3.86e-0485493C1510586
DiseaseIntellectual Disability

CHL1 KIF4A TET3 MED13 DYNC1I2

8.60e-04447495C3714756
Diseasesusceptibility to rheumatic fever measurement

FARP1 RYR3

9.93e-0428492EFO_0008416
Diseaseasthma, Eczema, allergic rhinitis

RYBP WDR36 LRRC43

1.08e-03121493EFO_0005854, HP_0000964, MONDO_0004979
Diseasecognitive behavioural therapy

RYBP DLGAP2

4.21e-0358492EFO_0007820
DiseaseAbnormality of chromosome segregation

ARHGAP44 FYB1

4.50e-0360492HP_0002916
Diseasecolorectal health

CHL1 DLGAP2 ARMC3

4.56e-03201493EFO_0008460

Protein segments in the cluster

PeptideGeneStartEntry
DFPKSRAPAKVPPKK

BPIFB3

256

P59826
PVEPVSLPKKKKPKK

CHD5

41

Q8TDI0
KPLPPTPEEDQILKK

BTK

186

Q06187
EGPDVKIPKFKKPKF

AHNAK

4966

Q09666
IPKKPPKGKFPITRE

DLGAP2

991

Q9P1A6
PKKPPNQKDVIKFPE

DEPDC1B

116

Q8WUY9
KKEVEPPPKDVFDPL

ARMC3

6

Q5W041
KEPKTPKAPKIPKEP

CHD7

666

Q9P2D1
KKVKKPKPEFPVYTP

DNAJC1

276

Q96KC8
VYKPLPKIQEKPKPT

ARMCX5

196

Q6P1M9
LEPVKPEPKPLVQEK

RBM27

81

Q9P2N5
FKKKPDPKPADEAVP

KCNK18

186

Q7Z418
IVPSVPKFPKEKIDP

CHL1

126

O00533
PKPPIEPEEEKTLKK

DYNC1I2

181

Q13409
KKPKLFLVVPPPQKD

NHSL1

1201

Q5SYE7
VEKPEKVVPPPLVDK

PDZD8

616

Q8NEN9
KIENVPKPPLKDPFL

FAM205A

456

Q6ZU69
KIENVPKPPLKDPFL

FAM205BP

186

Q63HN1
EEKPDKEPKPPFLKP

FYB1

71

O15117
KRSQPKKPKPEDPKF

KDM4B

376

O94953
FIPPKEKPIVKPKEA

KRR1

321

Q13601
IKQDPKLPVDKILPP

GGA2

161

Q9UJY4
PAPAPAKPKEEKIDL

MYL1

26

P05976
ISKKPKDPEPPEKEF

EXOSC10

801

Q01780
FRLFEEPKPKPKPVL

FARP1

316

Q9Y4F1
IFSKKYIPPPKEKRP

CRYBG2

96

Q8N1P7
EKVPEEKVKPGPPKV

COBL

136

O75128
EKVKPGPPKVPEKSV

COBL

141

O75128
PPKAEKKKAPKPERL

CTR9

986

Q6PD62
PLPQPPKDGDAIKKK

GLRA2

396

P23416
VPPKPKPSRVKEKFL

KIF4A

1021

O95239
IPPKPKPSRVKEKFL

KIF4B

1021

Q2VIQ3
PSIPVKQKPKEKEKP

KMT2A

1351

Q03164
KKPFPKIPEVPLHDT

EME1

136

Q96AY2
EEKAPPPKAAFKEPK

MLLT1

241

Q03111
KKKSPVKLEPSPPDV

PROCA1

266

Q8NCQ7
KKKKEPPKELRQDPP

LRRC43

546

Q8N309
PPPLVKVIEDLPKNK

TBC1D31

346

Q96DN5
IKVEEPEPVKKPPKE

SKA1

116

Q96BD8
EEAEKKKGKIPPPVP

NHSL2

991

Q5HYW2
ATPPPPKKEKKEKVE

RYBP

71

Q8N488
PKKKDVEFLPPQLPS

MED13

621

Q9UHV7
KVSKKLAPIPPKVPF

ARHGAP44

646

Q17R89
RDVKKKTEPKPPVPV

TET1

56

Q8NFU7
ELKKLPPLPVVEKPK

STAU2

271

Q9NUL3
PPLPVVEKPKLFFKK

STAU2

276

Q9NUL3
IYKPKPKAEVPEDKP

HSPA4L

786

O95757
VYKIKGPPKPEKEQP

RYR3

1931

Q15413
VPKGPEVKLPKAPEV

PRX

436

Q9BXM0
PKVPDVHLPKAPEVK

PRX

761

Q9BXM0
EIKKPPVAPKPKFVV

FGD6

6

Q6ZV73
PEIKKVPGFLEKKEP

PIEZO2

566

Q9H5I5
EPPTFKKEPPKEKEF

SMIM8

6

Q96KF7
PDRPPKEKKKKLPTP

TET3

571

O43151
KPVPVKPDMHIKEEP

ZMIZ2

681

Q8NF64
KPKEPPKVPKSAPFF

WDR36

776

Q8NI36