Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessosteoblast proliferation

JUNB MN1 PLXNB1

1.63e-0541253GO:0033687
GeneOntologyBiologicalProcessleukocyte activation

MUC19 JUNB PKN1 IL16 ZBTB7B YES1 ZFP36L2 MAPT

5.24e-051186258GO:0045321
GeneOntologyBiologicalProcessnegative regulation of cell population proliferation

SOX7 PKN1 LZTS2 ZBTB7B FOXA3 MN1 PLXNB1

1.07e-04961257GO:0008285
GeneOntologyBiologicalProcesscell activation

MUC19 JUNB PKN1 IL16 ZBTB7B YES1 ZFP36L2 MAPT

1.35e-041356258GO:0001775
GeneOntologyBiologicalProcessregulation of leukocyte activation

JUNB PKN1 IL16 ZBTB7B YES1 ZFP36L2

1.45e-04694256GO:0002694
GeneOntologyBiologicalProcessnegative regulation of osteoblast proliferation

MN1 PLXNB1

1.67e-0416252GO:0033689
GeneOntologyBiologicalProcessregulation of cell activation

JUNB PKN1 IL16 ZBTB7B YES1 ZFP36L2

2.32e-04756256GO:0050865
GeneOntologyCellularComponentmicrotubule

DYNC1LI1 LZTS2 CLASP1 MAPT WDR44

3.68e-04533255GO:0005874
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

DYNC1LI1 LZTS2 CLASP1 YES1 MAPT WDR44

5.45e-04899256GO:0099513
GeneOntologyCellularComponentspindle pole

DYNC1LI1 LZTS2 PLEKHG6

1.82e-03205253GO:0000922
GeneOntologyCellularComponentcentrosome

DYNC1LI1 LZTS2 PLEKHG6 CLASP1 YES1

1.93e-03770255GO:0005813
GeneOntologyCellularComponentspindle

DYNC1LI1 LZTS2 PLEKHG6 CLASP1

2.21e-03471254GO:0005819
GeneOntologyCellularComponentsupramolecular fiber

DYNC1LI1 LZTS2 CLASP1 YES1 MAPT WDR44

2.23e-031179256GO:0099512
GeneOntologyCellularComponentmidbody

PKN1 IL16 LZTS2

2.29e-03222253GO:0030496
GeneOntologyCellularComponentsupramolecular polymer

DYNC1LI1 LZTS2 CLASP1 YES1 MAPT WDR44

2.31e-031187256GO:0099081
GeneOntologyCellularComponentcleavage furrow

PKN1 PLEKHG6

2.41e-0361252GO:0032154
GeneOntologyCellularComponentcell division site

PKN1 PLEKHG6

4.10e-0380252GO:0032153
GeneOntologyCellularComponentmicrotubule organizing center

DYNC1LI1 LZTS2 PLEKHG6 CLASP1 YES1

4.14e-03919255GO:0005815
DomainARM-like

PLAA CLASP1 MN1

5.43e-03270253IPR011989
DomainPROTEIN_KINASE_TYR

AATK YES1

7.41e-0397252PS00109
DomainTyr_kinase_AS

AATK YES1

7.41e-0397252IPR008266
Domain-

PLAA PLXNB1 WDR44

9.66e-033332532.130.10.10
DomainWD40/YVTN_repeat-like_dom

PLAA PLXNB1 WDR44

9.82e-03335253IPR015943
DomainARM-type_fold

UBQLN2 PLAA CLASP1

1.01e-02339253IPR016024
DomainPkinase_Tyr

AATK YES1

1.28e-02129252PF07714
DomainProtein_kinase_ATP_BS

PKN1 AATK YES1

1.37e-02379253IPR017441
DomainSer-Thr/Tyr_kinase_cat_dom

AATK YES1

1.45e-02138252IPR001245
PathwayPID_P38_GAMMA_DELTA_PATHWAY

PKN1 MAPT

1.04e-0411202M209
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DYNC1LI1 SEC16B JUNB PKN1 CLASP1 MAPT MN1 WDR44

4.49e-0877425815302935
Pubmed

Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy.

UBQLN2 MAPT

4.96e-07225235082119
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

IL16 TENT4A YES1 MN1 WDR44

1.16e-0626525519240061
Pubmed

The protein kinase N (PKN) gene PRKCL1/Prkcl1 maps to human chromosome 19p12-p13.1 and mouse chromosome 8 with close linkage to the myodystrophy (myd) mutation.

JUNB PKN1

2.97e-0642529570957
Pubmed

Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.

PKN1 MAPT

7.43e-0662529546672
Pubmed

Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates.

YES1 MAPT

7.43e-06625216434389
Pubmed

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases.

PKN1 MAPT

2.22e-05102529199504
Pubmed

Phosphorylation of tau is regulated by PKN.

PKN1 MAPT

2.72e-051125211104762
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

DYNC1LI1 PKN1 UBQLN2 MAPT

2.75e-0524625415345747
Pubmed

Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5.

PKN1 MAPT

3.26e-051225212435421
Pubmed

Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta.

PKN1 MAPT

3.26e-051225212387894
Pubmed

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry.

PKN1 MAPT

3.26e-05122529832145
Pubmed

Functional proteomics mapping of a human signaling pathway.

SOX7 JUNB UBQLN2 LZTS2 YES1

5.59e-0559125515231748
Pubmed

A digenic cause of cleft lip in A-strain mice and definition of candidate genes for the two loci.

TENT4A MAPT

9.35e-052025215329828
Pubmed

KIF2A deficiency causes early-onset neurodegeneration.

CLASP1 MAPT

1.03e-042125236343267
Pubmed

Next-generation sequencing to generate interactome datasets.

JUNB PKN1 IL16 LZTS2 ZBTB7B YES1

1.31e-04114725621516116
Pubmed

rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.

DYNC1LI1 CLASP1 MAPT

1.43e-0414225330217970
Pubmed

A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain.

SOX7 MAPT

3.43e-043825239106860
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX7 JUNB ZBTB7B FOXA3 ZFP36L2

4.13e-0490825519274049
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DYNC1LI1 CLASP1 YES1 MAPT

4.14e-0449825436634849
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

DYNC1LI1 PKN1 PLAA

4.65e-0421225333462405
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

JUNB LZTS2 ZBTB7B CLASP1 YES1 ZFP36L2

5.51e-04149725631527615
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

SOX7 JUNB ZBTB7B FOXA3

5.77e-0454425428473536
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

DYNC1LI1 CLASP1 MAPT

5.97e-0423125316452087
Pubmed

A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.

UBQLN2 ZFP36L2

6.43e-045225215328020
InteractionSQSTM1 interactions

DYNC1LI1 PKN1 UBQLN2 LZTS2 PLAA ZBTB7B TENT4A ZFP36L2 MAPT

1.14e-051257259int:SQSTM1
InteractionDCTN3 interactions

DYNC1LI1 AATK CLASP1 MAPT

1.77e-05128254int:DCTN3
InteractionJAKMIP1 interactions

IL16 CLASP1 YES1

2.01e-0543253int:JAKMIP1
InteractionDCTN4 interactions

DYNC1LI1 AATK CLASP1 MAPT

2.74e-05143254int:DCTN4
InteractionZC2HC1A interactions

ZBTB7B YES1 MAPT

6.68e-0564253int:ZC2HC1A
InteractionPAQR9 interactions

UBQLN2 ZBTB7B

8.07e-0511252int:PAQR9
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

AATK MAPT

1.68e-02181202694
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 SEC16B TENT4A MAPT

2.57e-061742549d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX7 SEC16B TENT4A MAPT

2.57e-0617425453cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellMild/Remission-B_intermediate-14|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX7 ZBTB7B GCAT

6.59e-0514125369e32125a0e8f0c8561e5e7a93607f368f09546f
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|390C / Donor, Lineage, Cell class and subclass (all cells)

JUNB IL16 ZFP36L2

9.23e-05158253ad0e2371c0bc6e53d22518aa3a401cddcde3759f
ToppCellP28|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX7 JUNB MAPT

1.11e-041682534ee59a6147bbe7e4a03cc2d6fe9d6c10b18a3a06
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.34e-041792539af894dfbe44e9706f5d178769ceda3b4e2d89c0
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXA3 PLXNB1 EIF4EBP3

1.36e-04180253271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCelldroplet-Marrow-BM-1m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS2 ZFP36L2 MN1

1.36e-04180253ff34195bb7325e61fbf823c103c5e6115d8f1248
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.6.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.38e-04181253e8c715fa3a0fed43ad4788b2d06cf45ab2c9e202
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod|TCGA-Mesothelium / Sample_Type by Project: Shred V9

ZBTB7B PLXNB1 EIF4EBP3

1.40e-04182253bb1f815718397de96682697fcbd6014a992a28f7
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JUNB LZTS2 ZFP36L2

1.47e-04185253608c16c0ff251926e3e62a6cb66f835163302538
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX7 PKN1 IL16

1.52e-0418725350d5730e2cd4951d3ad0641fc81ae9f6ddabafe7
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.54e-041882538e1220066008aef171692c6afffcf31833a3fae8
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.54e-0418825331d7e62cce010eed1c2db6d6eb55806d27b26151
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-Activated_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.57e-041892531a891ae8517086fcf6443660976aef6413fa79ae
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.59e-041902534d15317a554b023fd874e28649af931d238cf83e
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.59e-041902539c0dc3c042751b2da772500876b6ff99bf809904
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.59e-0419025306ff7fb6b0f7ed1758e9829d4fe6c93d140c005e
ToppCellmetastatic_Brain-T/NK_cells-Naive_CD4+_T|metastatic_Brain / Location, Cell class and cell subclass

JUNB IL16 ZFP36L2

1.62e-041912534613eae77e2fbb1c526582de46ffed6bda61ea6b
ToppCellILEUM-inflamed-(6)_ILC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CLASP1 YES1 ZFP36L2

1.69e-041942534d51d49366c34ff1241770b4acc0167a43b3155a
ToppCell3'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.72e-0419525338ed4f48d450119cd50d6b85bd2d966a39d02c6b
ToppCellnormal_Lymph_Node|World / Location, Cell class and cell subclass

JUNB IL16 ZFP36L2

1.72e-041952534ae6ce15ca8400fc6b36fc4da8479aab295e488e
ToppCell3'-Pediatric_IBD|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.72e-04195253728776511e1f40f127f80ef1eecda6d6ad082392
ToppCellmetastatic_Brain-T/NK_cells|metastatic_Brain / Location, Cell class and cell subclass

JUNB IL16 ZFP36L2

1.72e-04195253618032c5b35bc42402162411caf4654f9718df5b
ToppCelltumor_Lung-T/NK_cells-Naive_CD4+_T|tumor_Lung / Location, Cell class and cell subclass

JUNB IL16 ZFP36L2

1.74e-04196253d5bab34992bf3ac08f20c07358f9745eff5b50d8
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JUNB IL16 ZFP36L2

1.74e-04196253476e71012c5cebb55e96edc9be1ff55e10ec8061
ToppCelllymphoid-T_cell-Regulatory_T_cell|World / Lineage, cell class and subclass

JUNB ZFP36L2 MAPT

1.74e-0419625342a4d706382be33d552ece1d0598d073857a8d4e
ToppCellSmart-seq2-lymph_node_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JUNB IL16 ZFP36L2

1.74e-041962533a8bd09a09c19df27c954d448f1bae945314c221
ToppCelllymphoid-T_cell-Regulatory_T_cell|lymphoid / Lineage, cell class and subclass

JUNB ZFP36L2 MAPT

1.77e-0419725373d5dcf076caae60ea32258b4e9dcac8979a661e
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.80e-04198253f6472649cf000918b98126cf02821d6779643292
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.80e-04198253cd1cd0ac2a66578aa38a139322295170002ec049
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-MAIT|Bac-SEP / Disease, condition lineage and cell class

JUNB ZFP36L2 PLXNB1

1.80e-04198253aea3654b16785aa9857ed646bd0d0dc9724df364
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUNB IL16 ZFP36L2

1.80e-04198253a17eb0e19e04e9d4fe14e19452d79c3c4559817a
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

JUNB IL16 ZFP36L2

1.80e-04198253fec6330dcea707f3ff65db736e9796d778de822c
ToppCell5'-Adult-LymphNode|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.82e-04199253098ff8badf67c382d8ddfa6b33f5035a26f2fd5f
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AATK MAPT PLXNB1

1.82e-041992536fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AATK MAPT PLXNB1

1.82e-041992535d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCellBAL-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

JUNB IL16 ZFP36L2

1.82e-04199253da180aaa53f995183522da0f2321bf0c0c8ee6ec
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AATK MAPT PLXNB1

1.82e-041992531bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AATK MAPT PLXNB1

1.82e-041992539dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JUNB IL16 ZFP36L2

1.85e-04200253ab3223c5ab13cdfae0eb441051024151c2194744
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CLASP1 MAPT MN1

1.85e-04200253306926cb7a847871641f02e03d52dc56fd55711c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

JUNB IL16 ZFP36L2

1.85e-0420025326251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCell5'-Adult-LymphNode-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JUNB IL16 ZFP36L2

1.85e-042002537dee3da190c78cb72970123eb8768618584ebeea
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JUNB IL16 ZFP36L2

1.85e-042002534f1855a9d96ac7c7ad62a709b265f9bd557b04fa
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MUC19 FOXA3

1.15e-039025272b800d26f1f06540fff35a57c23ca453b51edd8
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MUC19 FOXA3

1.15e-0390252cd2424a1b0a9264e91731691bda34dbd73867971
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MUC19 FOXA3

1.15e-0390252c96d653ab7761ecc0cd0835a5fc8ae6f9b151210
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZBTB7B MAPT

1.59e-03106252ede8407ad253080d1fa2a6e2aacf549ce220309a
ToppCellSevere-B_naive-13|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

JUNB ZFP36L2

1.90e-03116252f81a7c3e9cbf39124232d98e2a3a3e308137f391
ToppCellMild/Remission-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX7 ZBTB7B

2.53e-031342525bd1e3fa6278facd9e949e9e5e244e700190126b
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-3|TCGA-Breast / Sample_Type by Project: Shred V9

MUC19 SOX7

2.64e-031372523218c787a6b087f74b0804cec14b5ebb713391b7
ToppCelldroplet-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 ZFP36L2

2.75e-03140252d91ab34d6fded8c39d0f4456ce73281334660f74
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRT1 MAPT

2.83e-0314225267d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|390C / Donor, Lineage, Cell class and subclass (all cells)

SEC16B ZFP36L2

2.87e-0314325210473c0f030d5ff760263042dc4b584787cb4a7f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JUNB PRRT1

2.91e-0314425246177f0d6117e701bda86a99ac2a1b0e7ed66177
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|390C / Donor, Lineage, Cell class and subclass (all cells)

UBQLN2 ZFP36L2

2.95e-031452523a34c25ff77cd33fdca84742097cc7484066ebc4
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GCAT PLXNB1

2.95e-03145252186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCellSevere-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

JUNB MAPT

2.95e-03145252a24cad86509208bc7267b02ef1d1b0a25a2a7043
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SEC16B IL16

3.11e-03149252406a5ccfedbf43543f0346ff7ef3ce1d15c38f29
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SEC16B IL16

3.11e-0314925234a3075af794052763fc7c4135f3031f89da5caa
ToppCellLeuk-UTI-Lymphocyte-T_NK-dnT|Leuk-UTI / Disease, Lineage and Cell Type

AATK GCAT

3.11e-0314925253f145cf7089d948d41aa3c443e983e011826836
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17|bone_marrow / Manually curated celltypes from each tissue

JUNB ZFP36L2

3.11e-03149252264fe2ceac6379b3394d2bb47ef34692e4a64559
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL16 PLEKHG6

3.11e-031492528638b3819193d11411df58964069fec583f617f4
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SEC16B IL16

3.11e-03149252be698ecce34ddbdf57d08082b71268934675e74e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SEC16B IL16

3.11e-03149252183c77cc8f23b8406e7241a066cb684470002a3b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRT1 MAPT

3.15e-03150252afd651c654e715414eff64cf3a37378d057a56a2
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL16 PLEKHG6

3.23e-03152252b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRT1 MAPT

3.23e-03152252acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRT1 MAPT

3.23e-031522529d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

JUNB ZFP36L2

3.23e-031522529145dc014ed7f154c158d454dc2b9754396afcca
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|356C / Donor, Lineage, Cell class and subclass (all cells)

IL16 ZFP36L2

3.27e-031532525fb7d92cddc816c64071465e955ed0ea3bb45316
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKN1 TENT4A

3.27e-03153252489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GCAT EIF4EBP3

3.32e-031542520627161adaac5ee1f4aff05872b41473e6ae6eaf
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Tfh|blood / Manually curated celltypes from each tissue

JUNB ZFP36L2

3.32e-031542525ff380205fa7ab97ba21f6512bc9e14c0fb320b6
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG6 YES1

3.36e-03155252d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCellBac-SEP-Lymphocyte-T_NK-CD4_TEM|Bac-SEP / Disease, Lineage and Cell Type

SEC16B ZFP36L2

3.40e-03156252ef6bad99bcb30956863cd490c613e251f3b27ba0
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX7 YES1

3.40e-031562521928c86deb3bcd01db4ae76919a351066aadb39a
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK MAPT

3.40e-03156252d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCelldroplet-Lung-nan-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 ZFP36L2

3.44e-03157252b337937a88f62030114a28d70a63168417672767
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC16B LZTS2

3.44e-03157252ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GCAT MAPT

3.44e-03157252c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEC16B LZTS2

3.44e-03157252c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCellsevere_influenza-CD4+_T_naive|World / disease group, cell group and cell class (v2)

PRRT1 ZFP36L2

3.49e-031582528ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK MAPT

3.49e-03158252d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AATK MAPT

3.49e-03158252df614450e10629dc9115d7365397663e82f9e48f
ToppCellsevere_COVID-19-pDC|World / disease group, cell group and cell class (v2)

GCAT EIF4EBP3

3.53e-03159252e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRRT1 ZFP36L2

3.53e-03159252cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRRT1 ZFP36L2

3.53e-03159252330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKN1 MN1

3.53e-03159252c960df9e4fa980401941866b5081facac4590b4d
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

GCAT EIF4EBP3

3.53e-03159252ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX7 AATK

3.57e-03160252830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellmetastatic_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|metastatic_Brain / Location, Cell class and cell subclass

JUNB ZFP36L2

3.57e-03160252bc86c6ba1b7815ab944e1ec9da703f469373b8b1
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

PRRT1 MN1

3.57e-03160252d783d29150033e9181c0e30870070268fed3fd85
ToppCellCD8+_Memory_T_cell-RSV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

IL16 PLXNB1

3.62e-03161252f6d04f67da3557e80f13ef27bfabb94dcd80db2f
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG6 GCAT

3.62e-0316125278cb72c462167021195917a06052bcdc367ad890
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHG6 GCAT

3.62e-0316125206e7becfd11d6ef1a45a9cfdfcb40b812600038e
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

JUNB AATK

3.62e-0316125298c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SOX7 SEC16B

3.62e-031612523e5a125a25d55bf27652f456239b00b315d54d91
ToppCellMyeloid|World / shred on cell class and cell subclass (v4)

JUNB ZFP36L2

3.62e-03161252aee407d3739dba2d5216dcdb1579e7e4f483123d
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JUNB ZFP36L2

1.14e-0350112GAVISH_3CA_METAPROGRAM_CD4_T_CELLS_NAIVE_1
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JUNB ZFP36L2

1.14e-0350112GAVISH_3CA_METAPROGRAM_B_CELLS_STRESS
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JUNB ZFP36L2

1.14e-0350112GAVISH_3CA_METAPROGRAM_EPITHELIAL_STRESS
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JUNB ZFP36L2

1.14e-0350112GAVISH_3CA_METAPROGRAM_MACROPHAGES_STRESS_HSP
DrugTetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A

JUNB ZFP36L2 MAPT MN1 PLXNB1

2.07e-061962554587_DN
DrugGabazine [105538-73-6]; Down 200; 10.8uM; PC3; HT_HG-U133A

JUNB PLAA ZFP36L2 MAPT PLXNB1

2.07e-061962554236_DN
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A

PLEKHG6 ZFP36L2 MAPT MN1

5.40e-051922543804_DN
DrugAmprolium hydrochloride [137-88-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

PLEKHG6 ZFP36L2 MAPT PLXNB1

5.51e-051932544241_DN
DrugTrimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; PC3; HT_HG-U133A

JUNB PLAA ZFP36L2 MAPT

5.51e-051932544202_DN
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Down 200; 21uM; PC3; HT_HG-U133A

PLEKHG6 ZFP36L2 MAPT PLXNB1

5.51e-051932545050_DN
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A

PLEKHG6 ZFP36L2 MAPT PLXNB1

5.62e-051942543807_DN
DrugSeneciphylline [480-81-9]; Down 200; 12uM; PC3; HT_HG-U133A

PLEKHG6 ZFP36L2 MAPT PLXNB1

5.85e-051962544238_DN
DrugAmpicillin trihydrate [7177-48-2]; Down 200; 10uM; MCF7; HT_HG-U133A

JUNB PLEKHG6 ZFP36L2 PLXNB1

6.08e-051982541530_DN
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

AATK PLEKHG6 ZFP36L2 MAPT

6.08e-051982546657_DN
DrugFenbendazole [43210-67-9]; Down 200; 13.4uM; PC3; HT_HG-U133A

JUNB ZFP36L2 MAPT MN1

6.08e-051982543805_DN
DrugTheophylline monohydrate [5967-84-0]; Down 200; 20.2uM; PC3; HT_HG-U133A

JUNB ZFP36L2 MAPT PLXNB1

6.20e-051992544228_DN
DrugTinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A

PKN1 PLEKHG6 ZFP36L2 MAPT

6.20e-051992543430_DN
DrugArachidonic Acid

JUNB PLAA MAPT EIF4EBP3

8.68e-05217254ctd:D016718
Diseasefrontotemporal dementia (implicated_via_orthology)

UBQLN2 MAPT

4.16e-0512242DOID:9255 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

SOX7 YES1

3.10e-0432242DOID:10155 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

SEC16B MAPT PLXNB1

6.90e-04215243DOID:9970 (implicated_via_orthology)
Diseaseresponse to calcium channel blocker

MUC19 FOXA3

9.51e-0456242EFO_0007767
Diseaseurolithiasis

PKN1 ZFP36L2

1.20e-0363242MONDO_0024647
Diseasemean corpuscular hemoglobin concentration

SOX7 FOXA3 CLASP1 ZFP36L2 MN1

1.71e-031105245EFO_0004528
Diseaseneurotic disorder

AATK MAPT

3.05e-03101242EFO_0004257
Diseasetestosterone measurement

UBQLN2 PRRT1 ZBTB7B FOXA3 MAPT

3.20e-031275245EFO_0004908
Diseaseprimary biliary cirrhosis

IL16 MAPT

5.22e-03133242EFO_1001486
Diseaseneuroticism measurement

SOX7 AATK UBQLN2 MAPT

5.81e-03909244EFO_0007660
Diseaseserum gamma-glutamyl transferase measurement

SOX7 SEC16B LZTS2 YES1

5.93e-03914244EFO_0004532
Diseaseneurodegenerative disease (implicated_via_orthology)

UBQLN2 MAPT

6.17e-03145242DOID:1289 (implicated_via_orthology)
Diseaseautism spectrum disorder

SOX7 MAPT

7.10e-03156242EFO_0003756

Protein segments in the cluster

PeptideGeneStartEntry
STTPGGTLYATTPGG

EIF4EBP3

21

O60516
YSTGGAEPTTSSPGG

LZTS2

231

Q9BRK4
GSSPPGLSSTYTGGP

DYNC1LI1

11

Q9Y6G9
SGGTGPTEGYSPPAA

FAM104A

11

Q969W3
GYTSRGVGGGIPPIT

PLXNB1

171

O43157
PGVTGTTGTPAGVTG

MUC19

3401

Q7Z5P9
GTTGPSAGVTGTTGP

MUC19

5481

Q7Z5P9
GYTVTGSGTTALPGG

MUC19

8031

Q7Z5P9
YMSGSPGGSPGSGSA

IL16

516

Q14005
ALGGASGGYTTGPGP

GCAT

266

O75600
GGGYSSVGSGGVRPP

TENT4A

726

Q5XG87
SDSGYGTLIPGTPTG

PLEKHG6

586

Q3KR16
TPYAGGTPGGTGVTS

PRRT1

186

Q99946
STSTPDSYGGGGGPG

MN1

1111

Q10571
GGGGTPSSVDTYPYG

SOX7

186

Q9BT81
GYEVFSPSATGPSGG

AATK

916

Q6ZMQ8
GSSSSGYGAPGPGLV

FOXA3

86

P55318
ATGTGTFSPGASPGS

PKN1

526

Q16512
GYGGLTGGSSRGPPV

CLASP1

696

Q7Z460
GGSGPGDSYSPPTGT

ZBTB7B

246

O15156
FTGGGRYVPGSSGSS

PLAA

471

Q9Y263
GGYPVGSPGKVGLST

WDR44

21

Q5JSH3
RSGYSSPGSPGTPGS

MAPT

511

P10636
GSYPAGGGAGQTGTP

SEC16B

781

Q96JE7
GSTGSGGPTGPTVSS

UBQLN2

526

Q9UHD9
TSYGTLKEPSGGGGT

ZFP36L2

96

P47974
PFGGSSGVTPFGGAS

YES1

61

P07947
GGAGAAVGTGSSYPT

JUNB

196

P17275