Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset.	TBX3 RAX	4.61e-06	4	31	2	36383654
Pubmed	A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations.	GRIN2A ZMIZ1	4.61e-06	4	31	2	26163108
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TMEM131L KMT2C CEP192 GRWD1 AOPEP TRIM37 SMC6	3.83e-05	1084	31	7	11544199
Pubmed	SOX2 hypomorphism disrupts development of the prechordal floor and optic cup.	TBX3 RAX	5.96e-05	13	31	2	22522080
Pubmed	Decoding neuronal composition and ontogeny of individual hypothalamic nuclei.	TBX3 RAX	8.02e-05	15	31	2	33600763
Pubmed	Rax is a selector gene for mediobasal hypothalamic cell types.	TBX3 RAX	8.02e-05	15	31	2	23283339
Pubmed	The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling.	EPHB2 GRIN2A	1.60e-04	21	31	2	31577955
Pubmed	Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.	EPHB2 PAK5	1.76e-04	22	31	2	18628988
Pubmed	Cascade diversification directs generation of neuronal diversity in the hypothalamus.	TBX3 RAX	2.10e-04	24	31	2	33887179
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2C TBX3 ZMIZ1 BRD9	2.59e-04	351	31	4	38297188
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FNIP1 KMT2C CEP192 ZMIZ1 SPATA6 AOPEP ERI3	2.77e-04	1489	31	7	28611215
Pubmed	Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse.	EPHB2 RAX	3.29e-04	30	31	2	23426374
Pubmed	Yap and Taz are required for Ret-dependent urinary tract morphogenesis.	EPHB2 TBX3	3.52e-04	31	31	2	26243870
Pubmed	Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.	TMEM131L KMT2C	6.17e-04	41	31	2	34638806
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	FKBP15 RADIL CEP192 TRIM37	6.38e-04	446	31	4	24255178
Pubmed	Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man.	TBX3 RAX	7.43e-04	45	31	2	35951005
Pubmed	Identification of NPM-ALK interacting proteins by tandem mass spectrometry.	EPHB2 SMC6	8.11e-04	47	31	2	14968112
Pubmed	A human MAP kinase interactome.	ZC3H7A KMT2C TBX3 PAK5	8.79e-04	486	31	4	20936779
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	FKBP15 CEP192 PLCL1 TRPC5	6.17e-05	181	22	4	694
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000	ZC3H7A TBX3 PLCL1 ZMIZ1 GALT LARS2 AOPEP RAX	5.56e-05	967	31	8	Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500	ZC3H7A TBX3 PLCL1 GALT LARS2 RAX	6.10e-05	483	31	6	Facebase_RNAseq_e9.5_Maxillary Arch_500
CoexpressionAtlas	ratio_EmbryoidBody-blastocyst_vs_EmbryoidBody-fibro_top-relative-expression-ranked_2500_k-means-cluster#1	KMT2C CEP192 ZMIZ1 GRWD1 ERI3 RAVER2 SMC6 BRD9	6.70e-05	993	31	8	ratio_EB-blastocyst_vs_EB-fibro_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	EPHB2 TMEM131L CEP192 SPATA6 LARS2 TRIM37 XKR5 SMC6	1.06e-04	1060	31	8	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 PLEKHG2 MGAT5B AOPEP	9.89e-06	189	32	4	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 PLEKHG2 MGAT5B AOPEP	9.89e-06	189	32	4	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	mild_COVID-19_(asymptomatic)\|World / disease group, cell group and cell class (v2)	EPHB2 ZC3H7A DPYS ZMIZ1	1.14e-05	196	32	4	8cb3dcb3e5732f4bb060c87ca339b8997a1a8cd4
Disease	Hallux valgus	DPYS PLCL1 GRIN2A	3.80e-05	60	32	3	HP_0001822
Disease	Sezary Syndrome	KMT2C BRD9	3.93e-04	27	32	2	C0036920
Disease	colorectal cancer, colorectal adenoma	TBX3 PLCL1 ZMIZ1	5.96e-04	152	32	3	EFO_0005406, MONDO_0005575
Disease	colorectal cancer, endometrial neoplasm	MGAT5B AOPEP	9.55e-04	42	32	2	EFO_0004230, MONDO_0005575
Disease	nasopharynx carcinoma (is_marker_for)	KMT2C GRIN2A	1.00e-03	43	32	2	DOID:9261 (is_marker_for)
Disease	psoriasis	ZMIZ1 LARS2 PAK5	3.19e-03	273	32	3	EFO_0000676

Protein segments in the cluster

Peptide	Gene	Start	Entry
HGFGASMAAMVSFPP	ERI3	126	O43414
PGYSMIIKHPMDFGT	BRD9	171	Q9H8M2
ANFPSLGMASPHIMF	AOPEP	446	Q8N6M6
ITAGMGMLPFFPNQH	RAVER2	481	Q9HCJ3
MFYGTHFIMSPPTKS	RADIL	1	Q96JH8
GLQEPMMPFGASAFK	PAK5	291	Q9P286
MMPFGASAFKTHPQG	PAK5	296	Q9P286
ASMGMRPHGFRFGFP	KMT2C	2471	Q8NEZ4
QAQMKPIFSFAGHMG	GRWD1	201	Q9BQ67
PGGIDTHTHMQFPFM	DPYS	61	Q14117
FMTMFPHTPDNSFMG	MGAT5B	426	Q3V5L5
SGHMTPGMKIYIDPF	EPHB2	586	P29323
PHFQGSGDMASFLMT	FKBP15	496	Q5T1M5
RLKFPSVMHFGMSGF	OOSP4B	101	A0A2R8Y4Y8
ASFFAVHSNPMDMPG	FNIP1	231	Q8TF40
FENKGAMMGCSNPHP	GALT	171	P07902
GPSVVNHMMPASYDG	CEP192	1571	Q8TEP8
PCAFMGSMAPGHVAD	KHK	56	P50053
MNGPHMAHLGPFFGN	ENAM	66	Q9NRM1
VGGFHDSFMVMTQPP	TRIM37	921	O94972
HPSQFAMGGAFSSMA	TBX3	521	O15119
GMHYFMGKSKAGNPN	TMEM131L	506	A2VDJ0
VLSMFPYPSGKLHMG	LARS2	86	Q15031
MHLPGCAPAMADGSF	RAX	1	Q9Y2V3
FQTPGPMMDLHTGWF	PLCL1	671	Q15111
FMCHSMLGPFKFGSN	SMC6	56	Q96SB8
ANGGKMPFTMPEAFL	ZC3H7A	261	Q8IWR0
MFPQNAKPGFKHAGS	PLEKHG2	491	Q9H7P9
KFNGHMSEPSSEPMY	TRPC5	851	Q9UL62
TRFMGFMKPGHLAMP	XKR5	161	Q6UX68
RDFMFPGPNQMSGHH	SPATA6	106	Q9NWH7
FPHGNPGGTSMNDFM	ZMIZ1	901	Q9ULJ6
MPTYSGHFTMRSPFK	GRIN2A	1221	Q12879