Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH7 CCDC88C DNAH17 DNAH9 DNAH11

3.65e-0928966GO:0051959
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

1.89e-0818965GO:0008569
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

8.92e-0737965GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

2.19e-0570965GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

2.64e-04118965GO:0003774
GeneOntologyMolecularFunctionacetylcholine receptor regulator activity

SPDYE2 SPDYE2B SPDYE6

2.90e-0427963GO:0030548
GeneOntologyMolecularFunctionneurotransmitter receptor regulator activity

SPDYE2 SPDYE2B SPDYE6

3.23e-0428963GO:0099602
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

4.87e-0654965GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH7 DNAH17 DNAH9

4.91e-0625964GO:0005858
GeneOntologyCellularComponentmicrotubule associated complex

DNAH3 RANBP9 DNAH7 DNAH17 DNAH9 DNAH11

9.95e-05161966GO:0005875
GeneOntologyCellularComponentaxoneme

DNAH3 DNAH7 GLI3 DNAH17 DNAH9 DNAH11

3.88e-04207966GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 DNAH7 GLI3 DNAH17 DNAH9 DNAH11

3.98e-04208966GO:0097014
GeneOntologyCellularComponentexocytic vesicle

ATR WDR7 RAB40A SYT7 SYTL4 SYT5 RAB40B

6.87e-04320967GO:0070382
GeneOntologyCellularComponent9+2 motile cilium

DNAH3 DNAH7 DNAH17 SSX3 DNAH9 DNAH11

8.07e-04238966GO:0097729
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH7

9.17e-0410962GO:0036156
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH9

1.34e-0312962GO:0036157
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH7 DNAH9 DNAH11

6.31e-0714964IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH7 DNAH9 DNAH11

6.31e-0714964IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH7 DNAH9 DNAH11

6.31e-0714964IPR013602
DomainDHC_N2

DNAH3 DNAH7 DNAH9 DNAH11

6.31e-0714964PF08393
DomainMT

DNAH3 DNAH7 DNAH9 DNAH11

6.31e-0714964PF12777
DomainAAA_8

DNAH3 DNAH7 DNAH9 DNAH11

6.31e-0714964PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 MDN1 DNAH9 DNAH11

6.31e-0714964IPR011704
DomainAAA_5

DNAH3 MDN1 DNAH9 DNAH11

6.31e-0714964PF07728
DomainDHC_fam

DNAH3 DNAH7 DNAH9 DNAH11

8.57e-0715964IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH7 DNAH9 DNAH11

8.57e-0715964IPR004273
DomainDynein_heavy

DNAH3 DNAH7 DNAH9 DNAH11

8.57e-0715964PF03028
DomainSpy1

SPDYE2 SPDYE2B SPDYE6

2.11e-0511963PF11357
DomainSpeedy

SPDYE2 SPDYE2B SPDYE6

2.11e-0511963IPR020984
Domain-

HSPG2 LGALS9B NBEA CLSTN1 CRB2

1.30e-04959652.60.120.200
DomainSynaptotagmin

SYT7 SYTL4 SYT5

1.41e-0420963IPR001565
DomainPRELI_MSF1

SEC14L5 SEC14L1

3.87e-046962PS50904
DomainPRELI

SEC14L5 SEC14L1

3.87e-046962PF04707
DomainPRELI/MSF1_dom

SEC14L5 SEC14L1

3.87e-046962IPR006797
DomainDHC_N1

DNAH9 DNAH11

7.17e-048962PF08385
DomainDynein_heavy_dom-1

DNAH9 DNAH11

7.17e-048962IPR013594
DomainAAA+_ATPase

DNAH3 DNAH7 MDN1 DNAH9 DNAH11

8.85e-04144965IPR003593
DomainAAA

DNAH3 DNAH7 MDN1 DNAH9 DNAH11

8.85e-04144965SM00382
DomainConA-like_dom

HSPG2 LGALS9B RANBP9 NBEA CLSTN1 CRB2

9.36e-04219966IPR013320
DomainDOCK_C

DOCK4 DOCK6

1.40e-0311962IPR010703
DomainDHR-1_domain

DOCK4 DOCK6

1.40e-0311962IPR027007
DomainDHR_2

DOCK4 DOCK6

1.40e-0311962PS51651
DomainDHR_1

DOCK4 DOCK6

1.40e-0311962PS51650
DomainDOCK-C2

DOCK4 DOCK6

1.40e-0311962PF14429
DomainDHR-2

DOCK4 DOCK6

1.40e-0311962IPR027357
DomainCRAL_TRIO_N

SEC14L5 SEC14L1

1.40e-0311962PF03765
DomainDHR-2

DOCK4 DOCK6

1.40e-0311962PF06920
DomainDOCK

DOCK4 DOCK6

1.40e-0311962IPR026791
DomainCRAL-bd_toc_tran

SEC14L5 SEC14L1

1.67e-0312962IPR001071
DomainCRAL_TRIO_N

SEC14L5 SEC14L1

1.67e-0312962SM01100
DomainCRAL/TRIO_N_dom

SEC14L5 SEC14L1

2.63e-0315962IPR011074
DomainGOLD_dom

SEC14L5 SEC14L1

4.22e-0319962IPR009038
Domain2OG-FeII_Oxy

ALKBH6 PLOD1

4.22e-0319962PF03171
DomainGOLD

SEC14L5 SEC14L1

4.22e-0319962PS50866
DomainC2

SYT7 SYTL4 HECW2 SYT5

4.67e-03131964PF00168
DomainSOCS

RAB40A RAB40B

4.68e-0320962SM00253
Domain-

MTG1 DNAH3 RAB40A DNAH7 GEM DDX5 MDN1 RAB40B DNAH9 DNAH11

4.97e-0374696103.40.50.300
DomainCRAL_TRIO

SEC14L5 SEC14L1

5.15e-0321962PF00650
DomainFE2OG_OXY

ALKBH6 PLOD1

5.15e-0321962PS51471
DomainC2

SYT7 SYTL4 HECW2 SYT5

5.47e-03137964SM00239
Domain-

SEC14L5 SEC14L1

6.17e-03239623.40.525.10
DomainOxoglu/Fe-dep_dioxygenase

ALKBH6 PLOD1

6.17e-0323962IPR005123
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

2.39e-0727735M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

2.68e-0643735M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

3.37e-0645735M47670
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH7 DNAH17 DNAH11

7.38e-081410449373155
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH9 DNAH11

9.01e-077104331178125
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE2 SPDYE2B SPDYE6

2.15e-069104336272447
Pubmed

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.

HSPG2 NTN4 UNC5C

4.21e-0611104315186747
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE2 SPDYE2B SPDYE6

7.27e-0613104315611625
Pubmed

Alternative splicing of synaptotagmins involving transmembrane exon skipping.

SYT7 SYT5

8.86e-062104210556508
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYE2 SPDYE2B SPDYE6

1.71e-0517104315574121
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

DMGDH PLBD1 TMEM42 L3MBTL2 MDN1 HECW2 SLC5A6 DNAH17 MROH7 MED23 RBM47 ACTL10 SDHC CRB2

2.03e-0512421041430973865
Pubmed

Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.

BUB1 CLSPN

2.65e-053104218922873
Pubmed

Evolution of the Cdk-activator Speedy/RINGO in vertebrates.

SPDYE2 SPDYE6

2.65e-053104222763696
Pubmed

The mouse gene (Mobp) encoding myelin-associated oligodendrocytic basic protein maps to distal chromosome 9.

MAG COL7A1

2.65e-05310428875894
Pubmed

The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9.

OBSCN RANBP9

2.65e-053104218579686
Pubmed

PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.

ADM2 DACT2 RAB40A GLI3 ZNF747

4.62e-05130104526598620
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

5.29e-054104236140829
Pubmed

Linking PCNA-dependent replication and ATR by human Claspin.

ATR CLSPN

5.29e-054104217274954
Pubmed

Synaptotagmin-mediated vesicle fusion regulates cell migration.

SYT7 SYT5

5.29e-054104220473299
Pubmed

HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability.

ATR CLSPN

5.29e-054104225326330
Pubmed

Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase.

ATR CLSPN

5.29e-054104219828454
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH9

5.29e-054104211175280
Pubmed

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation.

ATR CLSPN

5.29e-054104216880517
Pubmed

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes.

RAB40A RAB40B

5.29e-054104225661869
Pubmed

Cyclin-dependent kinase 9-cyclin K functions in the replication stress response.

ATR CLSPN

8.80e-055104220930849
Pubmed

Synaptotagmins 3 and 7 mediate the majority of asynchronous release from synapses in the cerebellum and hippocampus.

SYT7 SYT5

8.80e-055104239116209
Pubmed

The lipid-binding SEC14 domain.

SEC14L5 SEC14L1

8.80e-055104217428729
Pubmed

Human claspin is required for replication checkpoint control.

ATR CLSPN

8.80e-055104212766152
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

8.80e-055104226909801
Pubmed

Chk1 and Claspin potentiate PCNA ubiquitination.

ATR CLSPN

8.80e-055104218451105
Pubmed

DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population.

DOCK4 DMAC2

8.80e-055104221682944
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40A RAB40B

8.80e-055104227909076
Pubmed

Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells.

ATR CLSPN

8.80e-055104216951182
Pubmed

Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).

ATR CLSPN

8.80e-055104221502314
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

HSPG2 COL7A1 NTN4 SPOCK3

9.54e-0579104418757743
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

DMGDH MTG1 ADCK5 DMAC2 DACT2 VARS2 MRM3 UCP3 MICU2 PCK2 SDHC

1.05e-049261041120877624
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 PNPLA2 OBSCN THAP8 CCDC88C ARHGEF40 MDN1 CASKIN1 ZNF324B DOCK6 ALKBH6 MMP17

1.17e-0411051041235748872
Pubmed

Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells.

SYT7 SYT5

1.32e-046104212860971
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH9 DNAH11

1.32e-046104233347437
Pubmed

Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress.

ATR CLSPN

1.32e-046104220424596
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TMEM201 ERBIN DDX5 GLI3 TENM1 PLEKHA7

1.44e-04263104634702444
Pubmed

Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.

ATR CLSPN

1.84e-047104220233725
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH11

1.84e-04710429256245
Pubmed

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.

DNAH17 DNAH11

1.84e-047104233139725
Pubmed

Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.

ATR CLSPN

1.84e-047104220029092
Pubmed

Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice.

HSPG2 PLOD1

1.84e-047104215377789
Pubmed

FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development.

RANBP9 MIB1

1.84e-047104225347788
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNB TMEM201 L3MBTL2 RANBP9 DPF2 ERBIN DDX5 ARHGEF40 MDN1 MIB1 ACIN1 PLOD1 PCK2

2.02e-0413531041329467282
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

GLI3 DNAH9 DNAH11

2.37e-0440104332317081
Pubmed

Evolution of the Rab family of small GTP-binding proteins.

RAB40A RAB40B

2.45e-048104211697911
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

DMGDH MTG1 ADCK5 DMAC2 DACT2 VARS2 MRM3 UCP3 MICU2 PCK2 SDHC

3.04e-0410471041118614015
Pubmed

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

SYT7 SYT5

3.14e-049104210531343
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

FLNB ATR ARHGEF40 MROH7 DOCK6

3.63e-04202104533005030
Pubmed

SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.

SYT7 SYT5

4.79e-0411104210734137
Pubmed

The expression and function of netrin-4 in murine ocular tissues.

HSPG2 NTN4

4.79e-0411104222281059
Pubmed

Identification of new high affinity targets for Roquin based on structural conservation.

UCP3 RBM47

4.79e-0411104230295819
Pubmed

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.

DNAH7 DNAH9

4.79e-0411104224421334
Pubmed

Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.

DDX5 BUB1

5.73e-0412104216595651
Pubmed

Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice.

HSPG2 CRB2

5.73e-0412104222072575
Pubmed

Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.

SOX12 UNC5C

5.73e-0412104226687222
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

DMGDH MTG1 ADCK5 DMAC2 VARS2 KYAT1 MRM3 UCP3 MICU2 PCK2 SDHC

6.01e-0411361041134800366
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

RANBP9 NBEA MDN1 MED23

6.24e-04129104423022380
Pubmed

A protein interaction landscape of breast cancer.

DOCK4 DPF2 CTSA ERBIN MDN1 ACIN1 PLEKHA7 PLOD1

6.48e-04634104834591612
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NBEA DPF2 DNAH7 MDN1 UNC5C MIB1 PCK2 DNAH11

6.75e-04638104831182584
Pubmed

Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.

HSPG2 GLI3

7.87e-0414104219783738
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK4 DOCK6

7.87e-0414104212432077
Pubmed

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

RAB40A SYTL4 RAB40B

8.64e-0462104311773082
Pubmed

FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).

ATR DDX5

9.07e-0415104227365398
Pubmed

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.

OR1D4 OR1D5

1.03e-0316104210673334
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

DOCK4 TMEM201 L3MBTL2 OSGEP DNAH7 CCDC88C MIB1 PLEKHA7 PLOD1

1.06e-03853104928718761
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

HECW2 CASKIN1 MIB1 DOCK6

1.18e-03153104410718198
Pubmed

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

RANBP9 CCDC88C NTN4

1.56e-0376104323535729
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

MTG1 GRM4 DNAH7 DDX5 HECW2 PLEKHA7

1.68e-03420104628065597
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

GLT8D1 ATR OSGEP MRM3 PLOD1

1.69e-03285104532838362
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

DMGDH DPF2 ERBIN DNAH7 DDX5 NTN4 MDN1 SYTL4 BUB1 ZNF747 RBM47

1.70e-0312931041115342556
Pubmed

Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function.

PNPLA2 UCP3

1.79e-0321104227185876
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

SYTL4 HECW2

1.79e-0321104237005481
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

HSPG2 COL7A1

1.79e-0321104227856617
Pubmed

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

WDR7 DMAC2 HECW2 ACIN1 CLSPN

1.91e-03293104531741433
Pubmed

DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system.

ATR CLSPN

1.97e-0322104215707391
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

NTN4 UNC5C

1.97e-0322104222726835
Pubmed

Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.

PDE3A GLI3

1.97e-0322104224376456
Pubmed

Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.

HSPG2 RANBP9 DDX5

2.08e-0384104325670202
Pubmed

Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways.

FLNB VARS2 GEM DDX5

2.09e-03179104418624398
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

ERBIN DDX5 PLEKHA7 RBM47

2.13e-03180104435198878
Pubmed

Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.

RAB40A RAB40B

2.15e-0323104220360680
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

HSPG2 GLI3

2.15e-0323104230814516
Pubmed

Genomic variants in an inbred mouse model predict mania-like behaviors.

OBSCN DNAH11

2.15e-0323104229768498
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

DMGDH PLBD1 OBSCN DDX5 PCK2

2.24e-03304104532235678
Pubmed

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.

NTN4 UNC5C

2.34e-0324104226633881
Pubmed

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.

PNPLA2 PCK2

2.34e-0324104227754788
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

WDR7 NBEA ERBIN DNAH7 SYTL4 GLI3 UNC5C CLSPN

2.35e-03777104835844135
Pubmed

Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.

MAG HSPG2

2.54e-0325104219373938
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

GLI3 DNAH11

2.54e-0325104227340223
Pubmed

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

DNAH3 SPOCK3 TENM1

2.61e-0391104322610502
Pubmed

Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.

GLI3 UNC5C

2.75e-0326104235927240
Pubmed

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.

FLNB WDR7 OSGEP SYT7 DDX5 RBM47

2.76e-03464104632457219
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

ERBIN UNC5C MIB1

2.86e-0394104332062451
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

WDR7 DACT2 RBM47

2.95e-0395104324029230
Pubmed

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.

DDX5 PCK2

2.96e-0327104226469385
Pubmed

Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.

DDX5 PCK2

2.96e-0327104236266428
Cytoband1p36.22

TMEM201 CLSTN1 PLOD1

8.30e-053710431p36.22
Cytoband2q32.3

DNAH7 HECW2

3.31e-041210422q32.3
Cytoband14q11.2

OSGEP ARHGEF40 ACIN1 PCK2

7.74e-04180104414q11.2
Cytoband17p13.3

OR1D4 MRM3 OR1D5

1.08e-0388104317p13.3
GeneFamilyDyneins, axonemal

DNAH3 DNAH7 DNAH17 DNAH9 DNAH11

4.83e-0917715536
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE2 SPDYE2B SPDYE6

1.24e-0512713756
GeneFamilySEC14 family|PRELI domain containing

SEC14L5 SEC14L1

2.26e-0467121295
GeneFamilySEC14 family|PRELI domain containing

SEC14L5 SEC14L1

2.26e-0467121063
GeneFamilySynaptotagmins

SYT7 SYT5

1.99e-0317712765
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MAG HSPG2 OBSCN UNC5C

3.70e-03161714593
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 SYT5 ALKBH6 DNAH9 DNAH11

1.59e-0615410369ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 SYT5 ALKBH6 DNAH9 DNAH11

1.59e-06154103658072ce422d09f2de602580325eaac6c4ec6c136
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 CCDC88C DNAH9 DNAH11

2.72e-06169103614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 CLSPN DOCK6 SEC14L1

4.87e-06187103635c382c0aabd46906113e5db30ea24bb8e658899
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 NBEA DNAH7 NTN4 DNAH9 DNAH11

6.19e-061951036fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 NBEA DNAH7 NTN4 DNAH9 DNAH11

6.19e-061951036eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 SYT5 DNAH9 DNAH11

2.43e-051481035d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 SYT5 DNAH9 DNAH11

2.43e-051481035c8e93b87212f55774223caa385859c566fa1981f
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MAG DOCK4 HSPG2 HECW2 SEC14L1

3.53e-0516010350d4880f85565d8c540c94a8f8109147b3029279a
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM7 SPOCK3 BUB1 TENM1 DNAH9

3.75e-051621035bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 LGALS9B NTN4 HECW2 SEC14L1

4.58e-051691035987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 PDE3A SYTL4 HECW2 SERINC4

4.71e-0517010358e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 PDE3A SYTL4 HECW2 SERINC4

4.71e-05170103567d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

DOCK4 DACT2 UNC5C MROH7 DNAH9

4.98e-051721035c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX12 PLBD1 ARHGEF40 BUB1 CLSPN

4.98e-051721035eba1568d4307e91c94fc616549057cbed8df5840
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|metastatic_Brain / Location, Cell class and cell subclass

DACT2 SYTL4 UNC5C MROH7 DNAH9

5.71e-05177103554f39be5d90363cfd44dea1a96ae06d3143aa795
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH7 SYT5 DNAH9 DNAH11

5.86e-0517810353b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

DNAH7 DNAH17 SYT5 DNAH9 DNAH11

5.86e-051781035d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HSPG2 FLNB PDE3A DOCK6 SEC14L1

6.02e-0517910351ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

6.18e-05180103516728b9a1c52097e3a460534be71a476ecc54f0f
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

COL7A1 PDE3A OBSCN UNC5C DOCK6

6.68e-051831035fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

6.86e-051841035a12a6a481e78adc62da1904431f62b119f70b15f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB PNPLA2 PDE3A MRM3 MED23

7.04e-05185103587151ab95530e70d61328b336518df58db584acb
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTN4 SPOCK3 GLI3 TENM1 PLEKHA7

7.22e-051861035948815663c212c4311329d503b5991cbbbff9808
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 VARS2 NTN4 PLEKHA7 RBM47

7.22e-051861035e83718fabb057100835d3357df407f283d23fe16
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

COL7A1 PDE3A OBSCN UNC5C DOCK6

7.40e-05187103562759efb660179402fb574ce5701c89a2e17bcfe
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE3A OBSCN GEM UNC5C PLOD1

7.40e-0518710358ee3bf885897efd634c3a0567637142a9f55e693
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SYT7 GEM NTN4 GLI3 TENM1

7.59e-0518810350e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DNAH7 DNAH9 NLRC3 DNAH11

7.78e-0518910353e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCOVID-19-kidney-Stressed_EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

8.18e-051911035d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

DOCK4 HSPG2 FLNB DOCK6 SEC14L1

8.18e-051911035c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 OBSCN DPF2 CYP2W1 SPOCK3

8.38e-0519210355a3c66fc3ae22bd9ac90ca137dee0bcabcd20ab8
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

DOCK4 HSPG2 FLNB DOCK6 SEC14L1

8.38e-0519210358a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 OBSCN DPF2 CYP2W1 SPOCK3

8.38e-0519210351f348e23843405abb1f1dc7d739fc5647333de16
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG SPOCK3 UNC5C RAB40B SEC14L5

8.38e-0519210353ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL7A1 LGALS9B CYP2W1 SPOCK3 GLI3

8.59e-0519310357c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DNAH7 DNAH9 NLRC3 DNAH11

8.59e-051931035ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

8.80e-051941035f76808666fb875fc787751cbfd924d9be20a8192
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL7A1 PDE3A OBSCN GLI3 UNC5C

8.80e-0519410352d66091097e106c7bee22e5281f50724700bdf8d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

TNFSF14 DACT2 GLI3 RBM47 CRB2

8.80e-051941035784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 DNAH9 DNAH11

8.80e-0519410354a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

8.80e-051941035f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

8.80e-051941035a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 DNAH9 DNAH11

9.01e-051951035649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX12 HSPG2 COL7A1 PDE3A ADM2

9.01e-05195103578cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRT1 WDR7 SYT7 SYTL4 SEC14L1

9.01e-051951035bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 DNAH9 DNAH11

9.01e-051951035129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 DNAH9 DNAH11

9.01e-0519510353e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.23e-0519610358ad8efb631164b46f0c082572270188e5ead20bf
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

DOCK4 HSPG2 NTN4 HECW2 SEC14L1

9.23e-051961035e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 DNAH7 CLSPN DNAH9 DNAH11

9.23e-051961035af4cdc61830685a888a1209826c23bcf54a43084
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.23e-051961035ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG SPOCK3 DNAH17 RAB40B SEC14L5

9.23e-05196103537a5f9f3988778655580bd0383811bb4930c1551
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 DNAH7 CLSPN DNAH9 DNAH11

9.23e-0519610356d02d494196e3f857d53eea46d9419690d43beca
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.23e-0519610359606ea7e42f707e69ea891b3521037613b9675f5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG SPOCK3 UNC5C RAB40B SEC14L5

9.46e-051971035032ccc91e604113da9bc34a6f9ddb1d45dea1892
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.46e-051971035cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.46e-0519710350f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG SPOCK3 UNC5C RAB40B SEC14L5

9.46e-05197103582b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 OBSCN CYP2W1 SPOCK3 GLI3

9.46e-0519710351e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.46e-05197103515d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 DNAH9 DNAH11

9.46e-051971035d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.69e-05198103507701c73137947ed4a27e225975329235bbb8734
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 BUB1 SYT5 DNAH9 DNAH11

9.69e-051981035f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.69e-05198103531ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.69e-0519810351378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.69e-051981035451003a21162eeae90739fdb502bb50b362d80c8
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 HECW2 MIB1 DOCK6 SEC14L1

9.69e-05198103545419f2804b4be79bae6632e71c54e1af482d115
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

DMGDH DNAH3 DNAH7 ZNF2 DNAH9

9.69e-0519810356d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.69e-051981035440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.69e-051981035fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NBEA DNAH7 DNAH9 DNAH11

9.69e-051981035d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 OBSCN CYP2W1 SPOCK3 GLI3

9.92e-05199103594a7867e800df352731796de8c24cba133c29622
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 RAB40A BUB1 SYT5 SEC14L5

9.92e-05199103592778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.92e-0519910358b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

9.92e-051991035da5a88749d859d535daa030d0974485906cc0ba7
ToppCellHealthy_Control-Lymphoid-T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

TNFSF14 CCDC88C CLSPN LINC02694 NLRC3

9.92e-051991035f22438fc9c02d0a4d7c936f9420b913aca851ea1
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A ZNF2 SPOCK3 SYT5 NLRC3

9.92e-0519910356e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A ZNF2 SPOCK3 SYT5 NLRC3

9.92e-0519910355f499595597c10857bba8272f62afe4d32d733ac
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAG SPOCK3 HECW2 UNC5C SEC14L5

1.02e-0420010354dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

COL7A1 ARHGEF40 SPOCK3 DNAH17 TENM1

1.02e-042001035f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

COL7A1 ARHGEF40 SPOCK3 DNAH17 TENM1

1.02e-04200103570a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAG SPOCK3 HECW2 UNC5C SEC14L5

1.02e-04200103526b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB SPOCK3 DOCK6 PLOD1 SEC14L1

1.02e-042001035b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

COL7A1 ARHGEF40 SPOCK3 DNAH17 TENM1

1.02e-0420010351639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAG SPOCK3 HECW2 UNC5C SEC14L5

1.02e-0420010351314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAG SPOCK3 HECW2 UNC5C SEC14L5

1.02e-0420010358b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

PDE3A NBEA ARHGEF40 DOCK6 MMP17

1.02e-04200103569edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 HSPG2 HECW2 DOCK6 SEC14L1

1.02e-042001035ced14d83222dbebca85c40540e76824e683354f3
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAG SPOCK3 HECW2 UNC5C SEC14L5

1.02e-042001035272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAG SPOCK3 HECW2 UNC5C SEC14L5

1.02e-0420010355f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG SPOCK3 DNAH17 UNC5C SEC14L5

1.02e-042001035829978708463a7459fe1041bd90196775bc4b531
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADM2 CYP2W1 SERINC4 SPDYE2B

1.47e-04115103436cbb8666b33199b7552879922789bc227525b7b
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADM2 CYP2W1 SERINC4 SPDYE2B

1.47e-0411510346f92e45cbe9924ade10cb8a41884b0202070ab31
ToppCellControl-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

ERBIN UNC5C SPDYE2 OGA

1.74e-041201034840d0ac995e2fa41996514753e4e03c4aa4a26d0
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

OBSCN MFSD4B LINC02872 GLI3

1.85e-0412210342aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

MAG COL7A1 ADCK5 MROH7

2.09e-04126103444b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP2W1 BUB1 LINC02694 PLEKHA7

2.36e-0413010340f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CYP2W1 BUB1 LINC02694 PLEKHA7

2.36e-041301034fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

DOCK4 SCRT1 UNC5C BUB1

3.96e-041491034651494e84be03dc7b061ebdfa91756a1c507b9b4
DiseasePR interval

DOCK4 HSPG2 PDE3A OBSCN ARHGEF40 MICU2 DNAH11

1.11e-03495957EFO_0004462
Diseasecortical surface area measurement

FLNB PDE3A CLSTN1 DNAH7 CCDC88C NTN4 GLI3 UNC5C MED23 LINC02694 PLEKHA7 DNAH11

1.27e-0313459512EFO_0010736
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAH9

1.69e-0319952DOID:10003 (implicated_via_orthology)
Diseaseosteochondrodysplasia (is_implicated_in)

HSPG2 FLNB

1.69e-0319952DOID:2256 (is_implicated_in)
DiseaseDisproportionate short stature

HSPG2 FLNB GLI3

1.99e-0377953C0878659

Protein segments in the cluster

PeptideGeneStartEntry
HLGTFEGRWRKLPKM

ACIN1

31

Q9UKV3
RKLQNWGGLPHPRGM

ALKBH6

56

Q3KRA9
SHRLWQLMGPAGRQD

ADM2

121

Q7Z4H4
QRLGPARHGEMWAIS

ERBIN

1046

Q96RT1
RPHLVAKHGRGMAVW

ACTL10

196

Q5JWF8
HRAWMHQKGLGPRGQ

ARHGEF40

286

Q8TER5
EGLFRRLPHLDMWNE

BUB1

1016

O43683
MDGWETRRKRIPGHD

ALLC

46

Q8N6M5
GHPHNKLRNRIWGMV

ADAM7

216

Q9H2U9
LRIERMHWPGSGQQL

GRM4

501

Q14833
QWAALLMGRHPDVQG

CYP2W1

306

Q8TAV3
MGRKLRPWDFQSHLV

DNAH11

446

Q96DT5
LMQRPVRLGQLWGSH

ADCK5

431

Q3MIX3
VAPMWNGRIRGIHRL

DMAC2

11

Q9NW81
WMRHGPFGRKKETIL

CLSTN1

391

O94985
AGSRLVMHLREWPAL

ALG1L

11

Q6GMV1
ALGPWMNSGKAHERA

MROH7

566

Q68CQ1
AQGVNMNRLPGWDKH

RANBP9

236

Q96S59
LRHRMNWLGRPSKVL

RAB40A

176

Q8WXH6
LRHGMDRLWRPSKVL

RAB40B

176

Q12829
RRKLMPGRIQLWGHQ

RBM47

211

A0AV96
WTRLHNGKLPTRAMD

HSPG2

1806

P98160
RWSIPADGRHLMVQK

GEM

21

P55040
KNRLPVMVWIHGGGL

CES1P1

131

Q9UKY3
ELPRGWEMKHDHQGK

HECW2

986

Q9P2P5
MVGPHAAARNLWGNL

CT47A1

151

Q5JQC4
REALPGWMRNNLSLG

PNPLA2

416

Q96AD5
KGMRPLHYAAWQGRK

CASKIN1

81

Q8WXD9
RLFEWHDGPLVQAMK

MDN1

1446

Q9NU22
RRNPAGTKWMEHVKL

GLI3

766

P10071
AQHSAEPWARMGGKR

MAGED4

331

Q96JG8
LPFQGAHRLMWAKIG

MAG

501

P20916
AHRLMWAKIGPVGAV

MAG

506

P20916
GMALGHLWRSRTGPQ

NLRC3

336

Q7RTR2
HPVGWSRRVGHGIKM

L3MBTL2

376

Q969R5
VLPGRWDDGLRHLVM

CRB2

716

Q5IJ48
MWSRRGLGVSRAPLH

LINC02872

1

A2RU37
TRQKGRWGPEERKMH

LGALS9B

76

Q3B8N2
MRRDGWPAMGIHGDK

DDX5

361

P17844
WPAMGIHGDKSQQER

DDX5

366

P17844
WGPGHKEATMELLRV

CCDC88C

1041

Q9P219
LSMHWVRQAPGKGLE

IGHV1-24

51

A0A0C4DH33
EAGMQKVRAWGPGLH

FLNB

546

O75369
DVARWFPGHMAKGLK

MTG1

26

Q9BT17
MAALYRPGLRLNWHG

PCK2

1

Q16822
LMGHSEWDHKRGPRG

PDE3A

321

Q14432
AGRGLIKGRDHLMWV

MED23

361

Q9ULK4
PMWNVRHLGSSAGKR

GLT8D1

301

Q68CQ7
QAGWEMFRAGHRTPL

OSGEP

301

Q9NPF4
RWDRFNKTLHQGMPE

PLBD1

521

Q6P4A8
LAIWGDKGAPHMQAL

MFSD4B

111

Q5TF39
KNVIAPLMTRHGRLW

PLOD1

401

Q02809
LQRGHGEWAEAMLPT

MIB1

351

Q86YT6
WHKGMERIQPGGRFE

OBSCN

4656

Q5VST9
LGNIFTRLPLKRMWH

CTSA

301

P10619
REMETNGPGHQLWRR

ATR

1431

Q13535
VAQAHKARPSMGDWR

DACT2

161

Q5SW24
NGDMLDLLKWRTHPD

DOCK4

581

Q8N1I0
DVALPGMRWVDGHKG

DOCK6

691

Q96HP0
IMRDLANITHDGPKW

DNAH17

2186

Q9UFH2
RRWALMIDPHGQANK

DNAH3

3076

Q8TD57
GIRHLMWDLGKGLKI

SDHC

131

Q99643
WGPAKRLLGDMRFLQ

DNAH7

2736

Q8WXX0
WAREVGKMIGLEHPL

DMGDH

251

Q9UI17
RLAWGRSEGGPMRHQ

COL7A1

806

Q02388
HKNMPTVAGGLRWAQ

DNAH9

601

Q9NYC9
VDLEGLNMRHLWRPG

SEC14L1

396

Q92503
LNMRHLWRPGVKALL

SEC14L1

401

Q92503
EGLNMRHLWRPGVKA

SEC14L5

386

O43304
RLVRIAWNPMDKGLH

LRRC30

256

A6NM36
LRNKDMHGAPGRVLW

OR1D4

291

P47884
LRNKDMHGAPGRVLW

OR1D5

291

P58170
GAGLRHWADMLANPR

SYT5

351

O00445
SGPGEVKHWKDMIAR

SYT7

376

O43581
LLHQTQMGDIWPGRK

SYTL4

156

Q96C24
RMRGDQVLWVPGSDH

VARS2

171

Q5ST30
LKDGPRLQAWLQHMG

THAP8

31

Q8NA92
WLLQGHMRSHTGEKP

SCRT1

261

Q9BWW7
PRMGNLALGRKLWAD

NTN4

36

Q9HB63
HGPKGAQMLREFQWL

OGA

571

O60502
LQPAQMHRFWRGLPL

MMP17

366

Q9ULZ9
DAWEPKVLRAGMGAH

MRM3

246

Q9HC36
WGRHTVGELLMADRK

SLC5A6

51

Q9Y289
VGWVLGPDHIMKHLR

KYAT1

256

Q16773
MLRGESGIWPRHAVK

NBEA

201

Q8NFP9
EFLGVLKNRMHRGLW

MICU2

386

Q8IYU8
VNSGHMIRSDLPRGW

PLEKHA7

46

Q6IQ23
INMISGPKRGEHAWT

SSX3

151

Q99909
SVHIRRDAGGMPLWL

TENM1

1586

Q9UKZ4
KPWFQLGHSMNPRAR

SPDYE2B

286

A6NHP3
DLHSDGPGRMRKFRW

CLSPN

1126

Q9HAW4
VWMAGGKLRLRASEH

LINC02694

41

Q8NAA6
MGVWGKKHLRLTHAP

ZNF503-AS2

1

A6NEH8
RGLWKGTLPNIMRNA

UCP3

176

P55916
LKRGDKPWMVDLHGS

ZNF2

66

Q9BSG1
LHWRLGEMVTRLPDG

TNFSF14

61

O43557
QWPDMHNAEISKRLG

SOX12

61

O15370
KPWFQLGHSMNPRAR

SPDYE2

286

Q495Y8
IPLLRKRWFQLGHSM

SPDYE6

281

P0CI01
KRWFQLGHSMNPRAR

SPDYE6

286

P0CI01
LKTGMAKHQWVHRPG

ZNF747

276

Q9BV97
RVWGKTHRIQMPSGL

SERINC4

86

A6NH21
WMEKRHRGPGLASGQ

DPF2

56

Q92785
WRQLLGLLPEHMAEK

TMEM201

271

Q5SNT2
MKEAGVDHRQWRGPI

SPOCK3

121

Q9BQ16
PHLQAGAMRRRFWGV

TMEM42

26

Q69YG0
VQLLQGEHMLRRGWP

WDR7

441

Q9Y4E6
LDAPQTRGHDWRMLA

UNC5C

856

O95185
GRFSGPLHRAWRMMN

TMEM251

21

Q8N6I4
DRRMGAAWQEPHRLL

ZNF324B

221

Q6AW86