Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of tooth enamel

AMELX AMELY

1.15e-056182GO:0030345
GeneOntologyMolecularFunctionhydroxyapatite binding

AMELX AMELY

2.14e-058182GO:0046848
GeneOntologyMolecularFunctionsodium ion binding

AMELX AMELY

6.94e-0514182GO:0031402
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring compression resistance

AMELX AMELY

1.92e-0423182GO:0030021
GeneOntologyMolecularFunctionalkali metal ion binding

AMELX AMELY

2.46e-0426182GO:0031420
GeneOntologyBiologicalProcessmRNA processing

CBLL1 CSTF2 RBM22 SF1 CSTF2T SF3B4

4.99e-06551186GO:0006397
GeneOntologyBiologicalProcessmRNA metabolic process

CBLL1 CSTF2 RBM22 SF1 CSTF2T SF3B4

8.90e-05917186GO:0016071
GeneOntologyBiologicalProcessRNA processing

CBLL1 CSTF2 RBM22 SF1 CSTF2T SF3B4 CHERP

1.65e-041500187GO:0006396
GeneOntologyBiologicalProcessenamel mineralization

AMELX AMELY

2.13e-0425182GO:0070166
GeneOntologyCellularComponentnuclear protein-containing complex

CSTF2 SMARCC1 RBM22 SF1 CECR2 CSTF2T SF3B4 SMAD4

8.37e-061377188GO:0140513
GeneOntologyCellularComponentmRNA cleavage and polyadenylation specificity factor complex

CSTF2 CSTF2T

2.25e-0426182GO:0005847
GeneOntologyCellularComponentmRNA cleavage factor complex

CSTF2 CSTF2T

3.21e-0431182GO:0005849
GeneOntologyCellularComponentspliceosomal complex

RBM22 SF1 SF3B4

7.81e-04215183GO:0005681
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SMARCC1 CECR2

3.04e-0396182GO:0070603
GeneOntologyCellularComponentU2-type spliceosomal complex

RBM22 SF3B4

3.11e-0397182GO:0005684
GeneOntologyCellularComponentendocytic vesicle

DVL2 AMELX AMELY

4.09e-03384183GO:0030139
GeneOntologyCellularComponentbasement membrane

AMELX AMELY

4.86e-03122182GO:0005604
GeneOntologyCellularComponentATPase complex

SMARCC1 CECR2

5.42e-03129182GO:1904949
GeneOntologyCellularComponentnuclear body

DVL2 CBLL1 CSTF2 SF1

6.52e-03903184GO:0016604
GeneOntologyCellularComponentchromatin

FOXD2 SMARCC1 CECR2 SMAD4 FOXB2

6.95e-031480185GO:0000785
GeneOntologyCellularComponentcollagen-containing extracellular matrix

AMELX AMELY LGALS4

9.96e-03530183GO:0062023
MousePhenoshort Tomes' process

AMELX AMELY

1.07e-062152MP:0030513
MousePhenoabnormal Tomes' process morphology

AMELX AMELY

3.22e-063152MP:0030512
MousePhenolarge mandible

AMELX AMELY

6.44e-064152MP:0030050
MousePhenoenamel pits

AMELX AMELY

1.07e-055152MP:0030460
MousePhenoshort upper incisors

AMELX AMELY

1.61e-056152MP:0030090
MousePhenosmall upper incisors

AMELX AMELY

2.25e-057152MP:0030081
MousePhenoshort lower incisors

AMELX AMELY

2.25e-057152MP:0030089
MousePhenoabnormal enamel rod pattern

AMELX AMELY

3.00e-058152MP:0002649
MousePhenoabnormal tooth wear

AMELX AMELY

4.81e-0510152MP:0030458
MousePhenosmall lower incisors

AMELX AMELY

5.88e-0511152MP:0030080
MousePhenobrittle teeth

AMELX AMELY

7.05e-0512152MP:0000126
MousePhenoreduced enamel thickness

AMELX AMELY

7.05e-0512152MP:0002577
MousePhenoabnormal enamel mineralization

AMELX AMELY

8.33e-0513152MP:0030450
MousePhenoincreased lung tissue damping

AMELX AMELY

8.33e-0513152MP:0011047
MousePhenoshort incisors

AMELX AMELY

9.71e-0514152MP:0004830
MousePhenoabnormal molar cusp morphology

AMELX AMELY

1.28e-0416152MP:0030457
MousePhenoabnormal incisor color

AMELX AMELY

1.28e-0416152MP:0010096
MousePhenoabnormal lung tissue damping

AMELX AMELY

1.28e-0416152MP:0011046
MousePhenoabnormal blastocyst morphology

CSTF2 SMARCC1 SMAD4 CHERP

1.34e-04259154MP:0004957
MousePhenoabnormal upper incisor morphology

AMELX AMELY

1.82e-0419152MP:0030137
MousePhenoabnormal preimplantation embryo morphology

CSTF2 SMARCC1 SMAD4 CHERP

1.88e-04283154MP:0014137
MousePhenoabnormal vertebrae morphology

DVL2 AMELX AMELY RBM22 SF3B4

1.93e-04546155MP:0000137
MousePhenovertebral transformation

AMELX AMELY SF3B4

2.01e-04110153MP:0003036
MousePhenoabsent teeth

AMELX AMELY

2.02e-0420152MP:0030610
MousePhenoabsent egg cylinders

SMARCC1 SMAD4

2.02e-0420152MP:0001694
MousePhenosmall incisors

AMELX AMELY

2.45e-0422152MP:0030079
MousePhenoabnormal molar crown morphology

AMELX AMELY

2.45e-0422152MP:0003932
MousePhenoabnormal ameloblast morphology

AMELX AMELY

2.45e-0422152MP:0002650
MousePhenoabnormal lower incisor morphology

AMELX AMELY

3.18e-0425152MP:0030136
MousePhenoabnormal tooth mineralization

AMELX AMELY

3.44e-0426152MP:0002817
MousePhenomicrodontia

AMELX AMELY

3.44e-0426152MP:0030088
MousePhenoabnormal enamel development

AMELX AMELY

3.71e-0427152MP:0030544
MousePhenoenlarged stomach

AMELX AMELY

5.57e-0433152MP:0003883
MousePhenoabnormal embryonic tissue morphology

DVL2 CSTF2 SMARCC1 RBM22 CECR2 SMAD4

6.81e-041116156MP:0002085
MousePhenoabnormal tooth color

AMELX AMELY

8.19e-0440152MP:0013129
MousePhenoabnormal zygomatic bone morphology

AMELX AMELY

8.60e-0441152MP:0005270
MousePhenoincreased gonad tumor incidence

SF1 SMAD4

8.60e-0441152MP:0009590
MousePhenoabnormal small intestine morphology

WASF1 RBM22 SMAD4

9.52e-04187153MP:0000496
MousePhenoembryonic lethality prior to organogenesis, complete penetrance

SMARCC1 SF1 SF3B4 SMAD4 CHERP

9.57e-04772155MP:0014259
MousePhenoembryonic lethality prior to tooth bud stage, complete penetrance

SMARCC1 SF1 SF3B4 SMAD4 CHERP

9.97e-04779155MP:0014257
MousePhenoembryonic lethality prior to organogenesis

SMARCC1 RBM22 SF1 SF3B4 SMAD4 CHERP

1.02e-031204156MP:0013292
MousePhenoabnormal enamel morphology

AMELX AMELY

1.04e-0345152MP:0002576
MousePhenoabnormal vertebral column morphology

DVL2 AMELX AMELY RBM22 SF3B4

1.04e-03787155MP:0004703
MousePhenodecreased tooth number

AMELX AMELY

1.08e-0346152MP:0030608
MousePhenoabnormal molar morphology

AMELX AMELY

1.33e-0351152MP:0002689
MousePhenoabnormal endoderm development

CSTF2 SMAD4

1.49e-0354152MP:0001685
MousePhenoabnormal tooth number

AMELX AMELY

1.60e-0356152MP:0030611
MousePhenoabnormal presacral vertebrae morphology

DVL2 RBM22 SF3B4

1.62e-03225153MP:0000459
MousePhenoincreased reproductive system tumor incidence

SF1 SMAD4

1.66e-0357152MP:0010287
MousePhenoenlarged lymph nodes

AMELX AMELY RBM22 CECR2

1.70e-03507154MP:0000702
MousePhenoexencephaly

DVL2 SMARCC1 CECR2

1.73e-03230153MP:0000914
MousePhenoabnormal tooth hard tissue morphology

AMELX AMELY

2.02e-0363152MP:0003930
MousePhenoabnormal duodenum morphology

RBM22 SMAD4

2.08e-0364152MP:0003271
MousePhenoembryonic lethality prior to tooth bud stage

SMARCC1 RBM22 SF1 SF3B4 SMAD4 CHERP

2.11e-031383156MP:0013293
MousePhenoabnormal stomach morphology

AMELX AMELY SMAD4

2.14e-03248153MP:0000470
MousePhenoabnormal lymph node size

AMELX AMELY RBM22 CECR2

2.46e-03561154MP:0000701
MousePhenoabnormal mesoderm development

CSTF2 SMAD4

2.78e-0374152MP:0001680
MousePhenoabnormal neural tube morphology

DVL2 SMARCC1 RBM22 CECR2

2.97e-03591154MP:0002151
MousePhenoabnormal egg cylinder morphology

SMARCC1 SMAD4

4.44e-0394152MP:0003085
MousePhenoabnormal lymph node morphology

AMELX AMELY RBM22 CECR2

5.01e-03683154MP:0002339
MousePhenoembryonic lethality between somite formation and embryo turning

SF1 SMAD4

5.61e-03106152MP:0006206
MousePhenoabnormal thoracic vertebrae morphology

DVL2 SF3B4

5.71e-03107152MP:0003047
MousePhenoabnormal tooth development

AMELX AMELY

5.82e-03108152MP:0000116
MousePhenoabnormal incisor morphology

AMELX AMELY

6.03e-03110152MP:0005358
MousePhenoabnormal inner cell mass morphology

SMARCC1 CHERP

6.35e-03113152MP:0002718
MousePhenosmall seminal vesicle

AMELX AMELY

6.90e-03118152MP:0001157
MousePhenoabnormal neural tube closure

DVL2 RBM22 CECR2

7.01e-03378153MP:0003720
MousePhenoabnormal lumbar vertebrae morphology

RBM22 SF3B4

7.02e-03119152MP:0003049
MousePhenoabnormal digestive system morphology

WASF1 AMELX AMELY RBM22 SMAD4

7.50e-031233155MP:0000462
DomainCSTF2_hinge

CSTF2 CSTF2T

8.77e-072182IPR025742
DomainAmelogenin

AMELX AMELY

8.77e-072182SM00818
DomainCSTF2_hinge

CSTF2 CSTF2T

8.77e-072182PF14327
DomainAmelogenin

AMELX AMELY

8.77e-072182PF02948
DomainCSTF_C

CSTF2 CSTF2T

8.77e-072182IPR026896
DomainAmelogenin

AMELX AMELY

8.77e-072182IPR004116
DomainCSTF_C

CSTF2 CSTF2T

8.77e-072182PF14304
DomainRRM_1

CSTF2 RBM22 CSTF2T SF3B4

4.05e-05208184PF00076
DomainRRM

CSTF2 RBM22 CSTF2T SF3B4

4.77e-05217184SM00360
Domain-

DVL2 FOXD2 SMARCC1 FOXB2

4.86e-052181841.10.10.10
DomainRRM_dom

CSTF2 RBM22 CSTF2T SF3B4

5.69e-05227184IPR000504
DomainRRM

CSTF2 RBM22 CSTF2T SF3B4

5.99e-05230184PS50102
DomainWHTH_DNA-bd_dom

DVL2 FOXD2 SMARCC1 FOXB2

7.29e-05242184IPR011991
Domain-

CSTF2 RBM22 CSTF2T SF3B4

7.53e-052441843.30.70.330
DomainNucleotide-bd_a/b_plait

CSTF2 RBM22 CSTF2T SF3B4

9.35e-05258184IPR012677
DomainTF_fork_head_CS_2

FOXD2 FOXB2

8.85e-0446182IPR030456
DomainTF_fork_head_CS_1

FOXD2 FOXB2

9.24e-0447182IPR018122
DomainFORK_HEAD_3

FOXD2 FOXB2

1.00e-0349182PS50039
DomainFH

FOXD2 FOXB2

1.00e-0349182SM00339
DomainFORK_HEAD_1

FOXD2 FOXB2

1.00e-0349182PS00657
DomainFORK_HEAD_2

FOXD2 FOXB2

1.00e-0349182PS00658
DomainForkhead

FOXD2 FOXB2

1.00e-0349182PF00250
DomainFork_head_dom

FOXD2 FOXB2

1.00e-0349182IPR001766
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

CSTF2 RBM22 SF1 CSTF2T SF3B4 CHERP

2.35e-07277156MM15414
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

CSTF2 RBM22 SF1 CSTF2T SF3B4 CHERP

2.67e-07283156M13087
PathwayREACTOME_METABOLISM_OF_RNA

CSTF2 RBM22 SF1 CSTF2T SF3B4 CHERP

2.34e-05612156MM15547
PathwayREACTOME_MRNA_SPLICING

RBM22 SF1 SF3B4 CHERP

4.84e-05201154MM15411
PathwayREACTOME_MRNA_SPLICING

RBM22 SF1 SF3B4 CHERP

5.96e-05212154M14033
PathwayREACTOME_METABOLISM_OF_RNA

CSTF2 RBM22 SF1 CSTF2T SF3B4 CHERP

6.03e-05724156M16843
PathwayREACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS

CSTF2 CSTF2T

1.99e-0420152MM15469
PathwayREACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS

CSTF2 CSTF2T

1.99e-0420152M497
PathwayWP_MRNA_PROCESSING

CSTF2 CSTF2T SF3B4

2.93e-04126153M39406
PathwayKEGG_SPLICEOSOME

RBM22 SF3B4 CHERP

3.00e-04127153M2044
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA

CSTF2 CSTF2T

4.22e-0429152M783
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA

CSTF2 CSTF2T

4.22e-0429152MM15444
PathwayWP_MRNA_PROCESSING

CSTF2 RBM22 CSTF2T SF3B4

1.07e-03451154MM15946
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION

CSTF2 CSTF2T

1.93e-0362152MM15426
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION

CSTF2 CSTF2T

2.25e-0367152M27694
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

DVL2 CSTF2 SMARCC1 SF1 CSTF2T SF3B4 CHERP

7.08e-1039918735987950
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

CBLL1 CSTF2 SMARCC1 RBM22 SF1 CECR2 CSTF2T SF3B4 CHERP

9.98e-10108218938697112
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

CBLL1 CSTF2 SMARCC1 WASF1 RBM22 CSTF2T SF3B4 CHERP

8.18e-0992218827609421
Pubmed

Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.

CSTF2 SMARCC1 RBM22 SF1 CSTF2T

1.26e-0815318528225217
Pubmed

SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.

AMELX AMELY SMAD4

3.32e-081318321490069
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CBLL1 CSTF2 SMARCC1 RBM22 SF1 SF3B4 SMAD4 CHERP

1.13e-07129418830804502
Pubmed

Folding, assembly, and aggregation of recombinant murine amelogenins with T21I and P41T point mutations.

AMELX AMELY

2.53e-07218221540557
Pubmed

The energetic basis for hydroxyapatite mineralization by amelogenin variants provides insights into the origin of amelogenesis imperfecta.

AMELX AMELY

2.53e-07218231239344
Pubmed

Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis.

AMELX AMELY

2.53e-07218219097165
Pubmed

A family of splice variants of CstF-64 expressed in vertebrate nervous systems.

CSTF2 CSTF2T

2.53e-07218219284619
Pubmed

Identification of the functional activity of the [A-4] amelogenin gene splice product in newborn mouse ameloblasts.

AMELX AMELY

2.53e-07218218394981
Pubmed

A solution NMR investigation into the murine amelogenin splice-variant LRAP (Leucine-Rich Amelogenin Protein).

AMELX AMELY

2.53e-07218220304108
Pubmed

Amelogenin-deficient mice display an amelogenesis imperfecta phenotype.

AMELX AMELY

2.53e-07218211406633
Pubmed

Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate.

AMELX AMELY

2.53e-07218224362885
Pubmed

Analysis of self-assembly and apatite binding properties of amelogenin proteins lacking the hydrophilic C-terminal.

AMELX AMELY

2.53e-07218211852235
Pubmed

A solution NMR investigation into the impaired self-assembly properties of two murine amelogenins containing the point mutations T21→I or P41→T.

AMELX AMELY

2.53e-07218223896516
Pubmed

Two related low molecular mass polypeptide isoforms of amelogenin have distinct activities in mouse tooth germ differentiation in vitro.

AMELX AMELY

2.53e-07218215647828
Pubmed

The receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenic pathway is elevated in amelogenin-null mice.

AMELX AMELY

2.53e-07218212851394
Pubmed

DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein.

AMELX AMELY

2.53e-0721824015654
Pubmed

Amelogenin, the major protein of tooth enamel: a new phylogenetic marker for ordinal mammal relationships.

AMELX AMELY

2.53e-07218218346915
Pubmed

Stage-Specific Role of Amelx Activation in Stepwise Ameloblast Induction from Mouse Induced Pluripotent Stem Cells.

AMELX AMELY

2.53e-07218234281250
Pubmed

The X-Y homologous gene amelogenin maps to the short arms of both the X and Y chromosomes and is highly conserved in primates.

AMELX AMELY

2.53e-0721821427830
Pubmed

Weaker dental enamel explains dental decay.

AMELX AMELY

2.53e-07218225885796
Pubmed

Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein.

CSTF2 CSTF2T

2.53e-07218212773396
Pubmed

Amelogenin genes and sexual dimorphism of teeth in humans and mice.

AMELX AMELY

2.53e-0721821463023
Pubmed

Transgene animal model for protein expression and accumulation into forming enamel.

AMELX AMELY

2.53e-07218211063035
Pubmed

Amelogenin X impacts age-dependent increase of frequency and number in labial incisor grooves in C57BL/6.

AMELX AMELY

2.53e-07218229337060
Pubmed

Translocation of enamel proteins from inner enamel epithelia to odontoblasts during mouse tooth development.

AMELX AMELY

2.53e-0721828179220
Pubmed

Regulation of amelogenin gene expression.

AMELX AMELY

2.53e-07218210200911
Pubmed

Molecular cloning and DNA sequence of rat amelogenin and a comparative analysis of mammalian amelogenin protein sequence divergence.

AMELX AMELY

2.53e-0721828297387
Pubmed

Developmental distribution of the polyadenylation protein CstF-64 and the variant tauCstF-64 in mouse and rat testis.

CSTF2 CSTF2T

2.53e-07218214681198
Pubmed

Structural variation of the pseudoautosomal region between and within inbred mouse strains.

AMELX AMELY

2.53e-0721828552598
Pubmed

Thermal denaturation of a recombinant mouse amelogenin: circular dichroism and differential scanning calorimetric studies.

AMELX AMELY

2.53e-07218216284958
Pubmed

Phosphorylation and ionic strength alter the LRAP-HAP interface in the N-terminus.

AMELX AMELY

2.53e-07218223477367
Pubmed

Protein interactions during assembly of the enamel organic extracellular matrix.

AMELX AMELY

2.53e-0721829041053
Pubmed

Truncated amelogenin and LRAP transgenes improve Amelx null mouse enamel.

AMELX AMELY

2.53e-07218226607574
Pubmed

Highly acidic pH facilitates enamel protein self-assembly, apatite crystal growth and enamel protein interactions in the early enamel matrix.

AMELX AMELY

2.53e-07218236569763
Pubmed

Exon4 amelogenin transcripts in enamel biomineralization.

AMELX AMELY

2.53e-07218225792521
Pubmed

A human X-Y homologous region encodes "amelogenin".

AMELX AMELY

2.53e-0721822004775
Pubmed

The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotype.

AMELX AMELY

2.53e-07218218701811
Pubmed

Loss of biological control of enamel mineralization in amelogenin-phosphorylation-deficient mice.

AMELX AMELY

2.53e-07218235219810
Pubmed

Of mice and men: anatomy of the amelogenin gene.

AMELX AMELY

2.53e-0721822689082
Pubmed

Expression of amelogenin in odontoblasts.

AMELX AMELY

2.53e-07218212667550
Pubmed

Human and mouse amelogenin gene loci are on the sex chromosomes.

AMELX AMELY

2.53e-0721822737677
Pubmed

Altering biomineralization by protein design.

AMELX AMELY

2.53e-07218216707492
Pubmed

Polyadenylation proteins CstF-64 and tauCstF-64 exhibit differential binding affinities for RNA polymers.

CSTF2 CSTF2T

2.53e-07218217029590
Pubmed

The amelogenin C-terminus is required for enamel development.

AMELX AMELY

2.53e-07218220042744
Pubmed

Amelogenin supramolecular assembly in nanospheres defined by a complex helix-coil-PPII helix 3D-structure.

AMELX AMELY

2.53e-07218221984897
Pubmed

Spatial- and temporal-restricted pattern for amelogenin gene expression during mouse molar tooth organogenesis.

AMELX AMELY

2.53e-0721823253061
Pubmed

A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chloride.

AMELX AMELY

2.53e-07218219086270
Pubmed

Leucine rich amelogenin peptide prevents ovariectomy-induced bone loss in mice.

AMELX AMELY

2.53e-07218234780561
Pubmed

Molecular structure of the mouse amelogenin genomic DNA.

AMELX AMELY

2.53e-0721828988368
Pubmed

Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscale.

AMELX AMELY

2.53e-07218221825148
Pubmed

Putative signaling action of amelogenin utilizes the Wnt/beta-catenin pathway.

AMELX AMELY

2.53e-07218219462488
Pubmed

Polypeptides translated from alternatively spliced transcripts of the amelogenin gene, devoid of the exon 6a, b, c region, have specific effects on tooth germ development in culture.

AMELX AMELY

2.53e-07218212489164
Pubmed

Isolation and characterization of a pseudoautosomal region-specific genetic marker in C57BL/6 mice using genomic representational difference analysis.

AMELX AMELY

2.53e-0721828618899
Pubmed

Amelogenin: a potential regulator of cementum-associated genes.

AMELX AMELY

2.53e-07218214653387
Pubmed

A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo.

AMELX AMELY

2.53e-0721827489712
Pubmed

The murine amelogenin promoter: developmentally regulated expression in transgenic animals.

AMELX AMELY

2.53e-0721829084642
Pubmed

Comparison of upstream regions of X- and Y-chromosomal amelogenin genes.

AMELX AMELY

2.53e-0721829714776
Pubmed

The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution.

AMELX AMELY

2.53e-07218225449314
Pubmed

Overlapping and distinct functions of CstF64 and CstF64τ in mammalian mRNA 3' processing.

CSTF2 CSTF2T

2.53e-07218224149845
Pubmed

Cryogenic transmission electron microscopy study of amelogenin self-assembly at different pH.

AMELX AMELY

2.53e-07218221597263
Pubmed

High-yield recombinant bacterial expression of 13 C-, 15 N-labeled, serine-16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protocol.

AMELX AMELY

2.53e-07218236585836
Pubmed

Characterization of copy number variation in genomic regions containing STR loci using array comparative genomic hybridization.

AMELX AMELY

2.53e-07218223948316
Pubmed

Isolation and characterization of a mouse amelogenin expressed in Escherichia coli.

AMELX AMELY

2.53e-0721828062146
Pubmed

A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta.

AMELX AMELY

2.53e-07218220067920
Pubmed

Transgenic mice that express normal and mutated amelogenins.

AMELX AMELY

2.53e-07218217384027
Pubmed

Antisense inhibition of AMEL translation demonstrates supramolecular controls for enamel HAP crystal growth during embryonic mouse molar development.

AMELX AMELY

2.53e-0721828392462
Pubmed

Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor.

AMELX AMELY

2.53e-07218231919099
Pubmed

The small bovine amelogenin LRAP fails to rescue the amelogenin null phenotype.

AMELX AMELY

2.53e-07218212958690
Pubmed

Novel LRAP-binding partner revealing the plasminogen activation system as a regulator of cementoblast differentiation and mineral nodule formation in vitro.

AMELX AMELY

2.53e-07218231621902
Pubmed

Reuptake of extracellular amelogenin by dental epithelial cells results in increased levels of amelogenin mRNA through enhanced mRNA stabilization.

AMELX AMELY

2.53e-07218216293627
Pubmed

[Types and frequencies of variants in Amelogenin gene in Chinese population].

AMELX AMELY

2.53e-07218218067069
Pubmed

Alternative splicing of the mouse amelogenin primary RNA transcript.

AMELX AMELY

2.53e-0721827820782
Pubmed

Amelogenins as potential buffers during secretory-stage amelogenesis.

AMELX AMELY

2.53e-07218225535204
Pubmed

The circadian clock modulates enamel development.

AMELX AMELY

2.53e-07218222653892
Pubmed

An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1.

AMELX AMELY

2.53e-07218220923441
Pubmed

Controlled Osteogenic Differentiation of Mouse Mesenchymal Stem Cells by Tetracycline-Controlled Transcriptional Activation of Amelogenin.

AMELX AMELY

2.53e-07218226709694
Pubmed

Leucine rich amelogenin peptide alters ameloblast differentiation in vivo.

AMELX AMELY

2.53e-07218223747796
Pubmed

Evolution in tooth developmental biology: of morphology and molecules.

AMELX AMELY

2.53e-0721828769659
Pubmed

Amelogenin promotes odontoblast-like MDPC-23 cell differentiation via activation of ERK1/2 and p38 MAPK.

AMELX AMELY

2.53e-07218221547453
Pubmed

Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta.

AMELX AMELY

2.53e-0721827782077
Pubmed

Cloning, characterization, and heterologous expression of exon-4-containing amelogenin mRNAs.

AMELX AMELY

2.53e-0721829062557
Pubmed

Alternative splicing of the mouse amelogenin primary RNA transcript contributes to amelogenin heterogeneity.

AMELX AMELY

2.53e-0721821445358
Pubmed

Altered amelogenin self-assembly based on mutations observed in human X-linked amelogenesis imperfecta (AIH1).

AMELX AMELY

2.53e-07218211877393
Pubmed

Comparison of body weight and gene expression in amelogenin null and wild-type mice.

AMELX AMELY

2.53e-07218216674684
Pubmed

Model system for evaluation of alternative splicing: exon skipping.

AMELX AMELY

2.53e-07218211879574
Pubmed

Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selection.

CSTF2 CSTF2T

2.53e-07218216207706
Pubmed

Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region.

AMELX AMELY

2.53e-0721829878259
Pubmed

Mouse amelogenin exons 8 and 9: sequence analysis and protein distribution.

AMELX AMELY

2.53e-07218215972588
Pubmed

Enamel ribbons, surface nodules, and octacalcium phosphate in C57BL/6 Amelx-/- mice and Amelx+/- lyonization.

AMELX AMELY

2.53e-07218227896287
Pubmed

Amelogenin-collagen interactions regulate calcium phosphate mineralization in vitro.

AMELX AMELY

2.53e-07218220404336
Pubmed

Maintenance of amelogenin gene expression by transformed epithelial cells of mouse enamel organ.

AMELX AMELY

2.53e-0721821444889
Pubmed

Partial rescue of the amelogenin null dental enamel phenotype.

AMELX AMELY

2.53e-07218218390542
Pubmed

Leucine-Rich Amelogenin Peptide (LRAP) Uptake by Cementoblast Requires Flotillin-1 Mediated Endocytosis.

AMELX AMELY

7.59e-07318227277399
Pubmed

Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions.

AMELX AMELY

7.59e-07318236702824
Pubmed

Origin, splicing, and expression of rodent amelogenin exon 8.

AMELX AMELY

7.59e-07318216998127
Pubmed

Early determination and permissive expression of amelogenin transcription during mouse mandibular first molar development.

AMELX AMELY

7.59e-0731828026631
Pubmed

Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin.

AMELX AMELY

7.59e-07318218515207
InteractionTLE5 interactions

DVL2 FOXD2 CSTF2 CSTF2T SF3B4 MYO15B SMAD4

2.28e-08443167int:TLE5
InteractionMECP2 interactions

CBLL1 CSTF2 SMARCC1 RBM22 SF1 CECR2 CSTF2T SF3B4 CHERP

1.31e-071287169int:MECP2
InteractionEWSR1 interactions

CSTF2 SMARCC1 SF1 CECR2 CSTF2T SF3B4 SMAD4 CHERP

1.51e-07906168int:EWSR1
InteractionTNIP2 interactions

CBLL1 CSTF2 SMARCC1 WASF1 RBM22 CSTF2T SF3B4 CHERP

2.21e-07952168int:TNIP2
InteractionPRPF40A interactions

SMARCC1 WASF1 SF1 SF3B4 SMAD4 CHERP

7.54e-07446166int:PRPF40A
InteractionSNW1 interactions

DVL2 RBM22 SF1 SF3B4 MYO15B SMAD4 CHERP

7.98e-07747167int:SNW1
InteractionWBP4 interactions

RBM22 SF1 SF3B4 CHERP

1.40e-06109164int:WBP4
InteractionSUZ12 interactions

CBLL1 SMARCC1 RBM22 SF1 CECR2 SF3B4

6.34e-06644166int:SUZ12
InteractionTLE3 interactions

CBLL1 CSTF2 RBM22 CECR2 CHERP

8.12e-06376165int:TLE3
InteractionPRPF39 interactions

RBM22 SF1 SMAD4

8.35e-0651163int:PRPF39
InteractionFUS interactions

CSTF2 SMARCC1 RBM22 SF1 SF3B4 CHERP

1.60e-05757166int:FUS
InteractionSF3A1 interactions

SMARCC1 RBM22 SF1 SF3B4 CHERP

2.41e-05471165int:SF3A1
InteractionPAPOLB interactions

CSTF2 CSTF2T

2.65e-0510162int:PAPOLB
InteractionSAXO4 interactions

DVL2 CSTF2 MYO15B

3.25e-0580163int:SAXO4
InteractionSNRPB2 interactions

RBM22 SF1 SF3B4 CHERP

4.04e-05255164int:SNRPB2
InteractionCPSF6 interactions

CBLL1 CSTF2 SMARCC1 RBM22 CSTF2T

4.09e-05526165int:CPSF6
InteractionCEP55 interactions

RBM22 SF1 LGALS4 CHERP

4.10e-05256164int:CEP55
InteractionDMRTB1 interactions

RBM22 SF1 SF3B4

5.27e-0594163int:DMRTB1
InteractionSF3A2 interactions

RBM22 SF1 SF3B4 CHERP

5.27e-05273164int:SF3A2
InteractionMIR106B interactions

SF1 SF3B4 CHERP

5.96e-0598163int:MIR106B
InteractionSS18L1 interactions

CSTF2 SMARCC1 SF3B4

5.96e-0598163int:SS18L1
InteractionCEBPB interactions

SMARCC1 RBM22 SF1 CSTF2T SF3B4 SMAD4 CHERP

6.12e-051443167int:CEBPB
InteractionRBFOX2 interactions

RBM22 SF1 SF3B4 CHERP

6.15e-05284164int:RBFOX2
InteractionKRTAP22-1 interactions

FOXD2 SMARCC1

6.17e-0515162int:KRTAP22-1
InteractionSNRPA1 interactions

RBM22 SF1 SF3B4 CHERP

7.61e-05300164int:SNRPA1
InteractionSMC5 interactions

CBLL1 CSTF2 SMARCC1 SF1 SF3B4 CHERP

7.66e-051000166int:SMC5
InteractionZFAND1 interactions

RBM22 SMAD4

7.98e-0517162int:ZFAND1
InteractionSTH interactions

CSTF2 CSTF2T

8.97e-0518162int:STH
InteractionWWOX interactions

DVL2 CSTF2 SMARCC1 RBM22 SMAD4

9.42e-05627165int:WWOX
InteractionEML5 interactions

DVL2 CECR2

1.00e-0419162int:EML5
InteractionMIRLET7G interactions

SF1 SF3B4 CHERP

1.01e-04117163int:MIRLET7G
InteractionRUNX1 interactions

CSTF2 SMARCC1 SF1 CSTF2T

1.02e-04324164int:RUNX1
InteractionU2AF2 interactions

DVL2 RBM22 SF1 SF3B4 CHERP

1.12e-04651165int:U2AF2
InteractionC19orf33 interactions

DVL2 SMARCC1

1.23e-0421162int:C19orf33
InteractionITCH interactions

DVL2 SMARCC1 SF1 SMAD4

1.47e-04356164int:ITCH
InteractionCWC15 interactions

RBM22 SF1 SF3B4

1.51e-04134163int:CWC15
InteractionACTC1 interactions

CSTF2 SMARCC1 SF1 SF3B4 CHERP

1.52e-04694165int:ACTC1
InteractionCUL4B interactions

CSTF2 SMARCC1 RBM22 SF1 CSTF2T

1.90e-04728165int:CUL4B
InteractionTAF15 interactions

SMARCC1 SF1 CSTF2T CHERP

2.48e-04408164int:TAF15
InteractionSNIP1 interactions

DVL2 RBM22 SMAD4 CHERP

2.70e-04417164int:SNIP1
InteractionKRTAP21-2 interactions

FOXD2 SMARCC1

2.71e-0431162int:KRTAP21-2
InteractionWWTR1 interactions

DVL2 CSTF2 SMARCC1 CSTF2T

2.82e-04422164int:WWTR1
InteractionTFIP11 interactions

RBM22 SF1 SF3B4 MYO15B

2.95e-04427164int:TFIP11
InteractionTOX2 interactions

CSTF2T LGALS4

3.08e-0433162int:TOX2
InteractionCPSF2 interactions

CSTF2 SMARCC1 CSTF2T

3.21e-04173163int:CPSF2
InteractionHOXA9 interactions

DVL2 SMAD4

3.27e-0434162int:HOXA9
InteractionLATS1 interactions

DVL2 SMARCC1 SF3B4 CHERP

3.31e-04440164int:LATS1
InteractionMPLKIP interactions

SF1 SF3B4

3.66e-0436162int:MPLKIP
InteractionWWP2 interactions

DVL2 SMARCC1 SF1 SF3B4 CHERP

3.70e-04840165int:WWP2
InteractionNXN interactions

DVL2 WASF1

4.09e-0438162int:NXN
InteractionMYCN interactions

CBLL1 SMARCC1 RBM22 SF1 SF3B4 CHERP

4.37e-041373166int:MYCN
InteractionAPBB1 interactions

SF1 SF3B4 CHERP

4.55e-04195163int:APBB1
InteractionSNRPA interactions

CSTF2 RBM22 SF1 SF3B4

4.68e-04482164int:SNRPA
InteractionCTNNBL1 interactions

RBM22 SF1 SF3B4

4.69e-04197163int:CTNNBL1
InteractionSNRPG interactions

RBM22 SF3B4 CHERP

4.76e-04198163int:SNRPG
InteractionUHRF2 interactions

DVL2 SMAD4 CHERP

4.90e-04200163int:UHRF2
InteractionNR2C2 interactions

DVL2 SMARCC1 RBM22 SF1 SF3B4 CHERP

4.91e-041403166int:NR2C2
InteractionSORBS3 interactions

DVL2 MYO15B CHERP

5.05e-04202163int:SORBS3
InteractionRFX6 interactions

CSTF2 LGALS4

5.74e-0445162int:RFX6
InteractionSF3B2 interactions

SF1 SF3B4 SMAD4 CHERP

6.10e-04517164int:SF3B2
InteractionSNRPB interactions

CSTF2 RBM22 SF3B4 CHERP

6.10e-04517164int:SNRPB
InteractionADAMTSL4 interactions

SMARCC1 MYO15B CHERP

6.22e-04217163int:ADAMTSL4
InteractionKRTAP19-2 interactions

FOXD2 SMARCC1

6.26e-0447162int:KRTAP19-2
InteractionRBM17 interactions

SF1 SF3B4 CHERP

6.30e-04218163int:RBM17
InteractionPKNOX2 interactions

CSTF2T MYO15B

6.53e-0448162int:PKNOX2
InteractionUFSP1 interactions

CSTF2 SMARCC1

6.80e-0449162int:UFSP1
InteractionBAG4 interactions

RBM22 SF1 SF3B4

6.82e-04224163int:BAG4
InteractionFIP1L1 interactions

CSTF2 CSTF2T SF3B4

6.91e-04225163int:FIP1L1
InteractionSYMPK interactions

CSTF2 SMARCC1 CSTF2T

6.91e-04225163int:SYMPK
InteractionUSB1 interactions

RBM22 SMAD4

7.37e-0451162int:USB1
InteractionSNRNP70 interactions

CSTF2 SMARCC1 SF3B4 SMAD4 CHERP

7.64e-04984165int:SNRNP70
InteractionCCDC97 interactions

SF3B4 CHERP

8.26e-0454162int:CCDC97
InteractionSFPQ interactions

CBLL1 SMARCC1 SF1 SF3B4

8.39e-04563164int:SFPQ
InteractionNHSL2 interactions

WASF1 MYO15B

8.56e-0455162int:NHSL2
InteractionSRSF1 interactions

CBLL1 SMARCC1 SF3B4 CHERP

8.79e-04570164int:SRSF1
InteractionDDX39B interactions

SMARCC1 RBM22 SF1 SMAD4

8.79e-04570164int:DDX39B
InteractionSF3B1 interactions

RBM22 SF1 SF3B4 CHERP

8.85e-04571164int:SF3B1
InteractionATP23 interactions

CSTF2 CSTF2T

9.52e-0458162int:ATP23
InteractionFAM168B interactions

CSTF2 CSTF2T

9.52e-0458162int:FAM168B
InteractionRBM10 interactions

CBLL1 SF1 SF3B4

9.70e-04253163int:RBM10
InteractionCSNK1D interactions

DVL2 SF3B4 SMAD4

9.81e-04254163int:CSNK1D
InteractionCPSF1 interactions

CBLL1 CSTF2 CSTF2T

9.92e-04255163int:CPSF1
InteractionARHGEF19 interactions

RBM22 SF1

1.02e-0360162int:ARHGEF19
InteractionKIAA1143 interactions

CSTF2 RBM22

1.05e-0361162int:KIAA1143
InteractionNCK2 interactions

WASF1 SF1 SF3B4

1.07e-03262163int:NCK2
InteractionBCAS2 interactions

RBM22 SF1 SF3B4

1.17e-03270163int:BCAS2
InteractionMMUT interactions

SF1 SMAD4

1.19e-0365162int:MMUT
InteractionPPP1R16B interactions

DVL2 SF3B4

1.19e-0365162int:PPP1R16B
InteractionHNRNPC interactions

SMARCC1 RBM22 SF1 SF3B4

1.31e-03634164int:HNRNPC
InteractionARHGAP12 interactions

WASF1 SF1

1.31e-0368162int:ARHGAP12
InteractionSNRNP40 interactions

CBLL1 SMARCC1 RBM22 CHERP

1.33e-03637164int:SNRNP40
InteractionCDH23 interactions

DVL2 WASF1

1.42e-0371162int:CDH23
InteractionVGLL3 interactions

SMARCC1 MYO15B

1.46e-0372162int:VGLL3
InteractionUSP4 interactions

CSTF2 SF3B4 SMAD4

1.48e-03293163int:USP4
InteractionYTHDF1 interactions

RBM22 SF1 SF3B4

1.61e-03302163int:YTHDF1
InteractionCIC interactions

FOXD2 SMARCC1 SMAD4 CHERP

1.63e-03673164int:CIC
GeneFamilyRNA binding motif containing

CSTF2 RBM22 CSTF2T SF3B4

2.31e-05213154725
GeneFamilyForkhead boxes

FOXD2 FOXB2

5.69e-0443152508
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CECR2 LGALS4

4.93e-04821826875a10abf1221b3dfd954c319b5e8e12fac1ff2
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CECR2 LGALS4

4.93e-0482182259bb4ae0373d8352cb1c3bff08f66b89a298440
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CECR2 LGALS4

4.93e-048218289aff8676f98e062d0e69b38c7184e51aa1a915e
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.31e-03134182d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.31e-03134182459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)|Cerebellum / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.31e-031341820be389f416818a22e80098dd809fdf45b14171e8
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.31e-03134182d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)|Hippocampus / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.32e-0313518297989546826bf3739e1b86a10832a457fd37c5d2
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.32e-031351824cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.32e-031351826bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

FOXD2 LGALS4

1.32e-031351827e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MYO15B LGALS4

1.55e-03146182e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

CSTF2 MYO15B

1.59e-0314818280470353e12599440f711b6e107730763376d04d
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MYO15B LGALS4

1.61e-0314918292a8931a51db619fb5f0638d319c02e7838f6559
ToppCellMild_COVID-19-Myeloid-TRAM2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CECR2 LGALS4

1.72e-03154182ab648f6b29eb9e499e46cbdbaf3c5cf6b94d1f64
ToppCellVE-CD8-naive_CD4|VE / Condition, Cell_class and T cell subcluster

CSTF2 CSTF2T

1.85e-03160182255d2a150bfe19ee3d4d34533feb9c37ce73d225
ToppCellwk_20-22-Hematologic-Myeloid-GMP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SMARCC1 MYO15B

1.99e-03166182d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SMARCC1 CHERP

1.99e-0316618232d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellTCGA-Colorectal|World / Sample_Type by Project: Shred V9

FOXD2 LGALS4

1.99e-03166182c018cd8c7a82251c67e3dc812d4d21e527a43456
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

MYO15B CHERP

2.02e-031671821e2fc1637769405a61f4c7e44945712a1888a299
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.02e-03167182720dc5855c856b478b5ca90156b30bfcc5518d60
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CECR2 LGALS4

2.06e-031691824e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.11e-03171182f2b31c97bbcc5164fc279ed0362007878887ad5e
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CSTF2 MYO15B

2.16e-03173182efb8072475000888efe088d00e870c56ffad4172
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASF1 SF1

2.16e-03173182694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.16e-03173182021457c7bdb55de7351e43322d360e8fd7061658
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CSTF2 MYO15B

2.18e-0317418258300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.18e-03174182ca067e8ec55bbc3deafc09f08bc13af08364d165
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXD2 CECR2

2.21e-031751827be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CSTF2 MYO15B

2.21e-0317518287e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.23e-03176182e7502a345b2da83a9a60f50cf78f1aef385c99df
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.36e-031811821d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.36e-031811820069e8308de932df43660bbe926637c57b8bf7f6
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

WASF1 CECR2

2.39e-03182182a5fd392178c2f533e265d2e3ce63b90c2553e4c1
ToppCellB_cell_maturation-immature_B_cell|World / Lineage and Cell class

WASF1 CECR2

2.39e-031821822c7c51ebc4125d8a33454ffee0b143579ce5e451
ToppCell5'-Adult-LymphNode-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.39e-0318218249e4b362f88d235ed12aabcabb54787c16e32cb7
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSTF2 LGALS4

2.39e-03182182818b5155ec81f0059048d6070a108116ecd72e3c
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.44e-03184182886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.44e-03184182a2191dd5546efd357b23e625beb3c5820476f243
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.44e-03184182936b39377eebea3961d702532779f6cd27953be7
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.46e-03185182b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.52e-0318718297e520705491c8f52a32025311a9fa7b9176979a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.54e-03188182505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.57e-0318918242ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.57e-03189182784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.57e-0318918237ecbd73408d462b47d7e5611f203143e08a2689
ToppCellMS-CD8-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

DVL2 SMAD4

2.60e-031901828c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.60e-031901822de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.60e-03190182ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.60e-0319018207f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.62e-031911822b056cbe2e82e056e1f798974999378460eb1d16
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.62e-031911822110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSTF2 SMAD4

2.62e-031911827411b253b16e4d472be0925dee49188f0fd6b0b5
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.62e-03191182a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 MYO15B

2.62e-03191182f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.65e-031921829f7e0d610741288d0779bd7c02852c791431e4ea
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.68e-03193182930df79b0600f43617052313294be33bcf5631f0
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.68e-0319318232eb026d4317c1499d51294d396dfd5f293f9deb
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.70e-0319418207d8e38cbc2c7f0564c14f7c365f345f901b73b2
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCC1 CECR2

2.70e-031941828ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell3'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.70e-031941821a188e52f2f0b6eca3e8d4a4671d9beab0fbbb88
ToppCell3'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.73e-031951823365768101454060b9ea96ef6b426c76c150bc8f
ToppCell5'-GW_trimst-2-LargeIntestine|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.73e-031951821a4a5623fa0318ef388cc228c7060e0586a7acf9
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.76e-0319618253dcac5e34c08c67a897dd5fbfbe88ea37e15585
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CBLL1 SMAD4

2.76e-031961827e98380d815fbf6254289ace2af37aac6fef51e8
ToppCellControl-B_naive-8|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASF1 SF1

2.76e-0319618254074da84000e4749ade8acc542f05a275bf829f
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pre_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

WASF1 SF1

2.76e-031961826ba02b806d440eed45bad7616bf3b8be57034427
ToppCellControl-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASF1 SF1

2.79e-03197182925bf0d38e4ce279fa45f455546ebd199282c0df
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CECR2 LGALS4

2.79e-03197182bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.79e-03197182755a53d4206354583bc5b76b63a0b1c9892b7382
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.79e-03197182c14dac1c8ba9d366d9dbefedb69f7b29d6fe6f4d
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.79e-03197182a137412f29a06e29efe8a5dd641839ff2aeeda0c
ToppCell3'-Adult|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.81e-03198182302adb42089ff22fffc4f01af572ca2e151f7ce7
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SMARCC1 CECR2

2.81e-031981826d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCellImmune_cells-large_pre-B.|Immune_cells / Lineage and Cell class

SMARCC1 SF3B4

2.81e-03198182bc9ceefadb153907d2854d1f736d17349003cb31
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD2 LGALS4

2.81e-031981827c4993be089979e79ca1a160c0c4059c422eac6d
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SMARCC1 CECR2

2.81e-031981827943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FOXD2 SF3B4

2.81e-03198182882710bd6215e299257dd3df234292db9a2823ba
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AMELX MYO15B

2.81e-03198182732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

WASF1 SF1

2.84e-03199182dd94e42b62af7cbd69c472681d3c758552694ae2
ToppCellerythropoietic-Basophilic_Erythroblast|erythropoietic / Lineage and Cell class

SMARCC1 SF1

2.84e-0319918239c4adef3e02f948414f866aa22ac76f44b7b7db
ToppCellmegakaryocytic-CD34+_Megakaryoblast|megakaryocytic / Lineage and Cell class

SMARCC1 SF1

2.84e-0319918299a65887d3c8a2cde26693dd74404b101bba9d58
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

FOXD2 CECR2

2.87e-03200182332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.87e-03200182156a949b3b59fb2b00e4f4a8933169f247a5f660
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.87e-032001823e13c9a4ba99a7dfbf738b0fb63fb54b4dee5897
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.87e-0320018273bfdf068a8ecbefc1e6afe9686df73658ee042f
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

CECR2 MYO15B

2.87e-03200182e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15B LGALS4

2.87e-03200182ce0c259f7fa4c0aa6d00e0bb362c029e96fce19e
ComputationalNeighborhood of MSN

SMARCC1 SF1

5.84e-0428142GCM_MSN
ComputationalNeighborhood of SMARCC1

SMARCC1 SF1

1.02e-0337142GCM_SMARCC1
ComputationalNeighborhood of AIP

SMARCC1 SF1

1.19e-0340142GCM_AIP
Drugganoine

AMELX AMELY

1.77e-063182CID000131592
DrugAmpF

AMELX AMELY

3.23e-0511182CID000193541
Drugleucomalachite green

AMELX AMELY

3.88e-0512182CID000067215
Drugamido black

AMELX AMELY

4.58e-0513182CID005473482
Diseaseamelogenesis imperfecta type 1E (implicated_via_orthology)

AMELX AMELY

3.12e-072172DOID:0110058 (implicated_via_orthology)
Diseaseautosomal dominant hypocalcemia (biomarker_via_orthology)

AMELX AMELY

1.87e-064172DOID:0090109 (biomarker_via_orthology)
Diseasecervical cancer (is_marker_for)

SF3B4 SMAD4

1.95e-0436172DOID:4362 (is_marker_for)
Diseasecolorectal carcinoma (is_marker_for)

SMARCC1 SMAD4

2.06e-0437172DOID:0080199 (is_marker_for)
Diseasehepatocellular carcinoma (is_marker_for)

SMARCC1 SF3B4 SMAD4

6.43e-04301173DOID:684 (is_marker_for)
Diseasehepatocellular carcinoma (biomarker_via_orthology)

SF3B4 SMAD4

1.74e-03108172DOID:684 (biomarker_via_orthology)
Diseaserenal cell carcinoma (is_marker_for)

SMARCC1 SMAD4

2.43e-03128172DOID:4450 (is_marker_for)
Diseasephosphatidylcholine measurement

MYO15B LGALS4

1.14e-02284172EFO_0010226

Protein segments in the cluster

PeptideGeneStartEntry
AMPLPPHPGHPGYIN

AMELX

16

Q99217
AMPLPPHPGHPGYIN

AMELY

16

Q99218
YLGPPHQGPPMHHVP

CSTF2

346

P33240
CPPGVPYHPHQPAHP

CECR2

916

Q9BXF3
HPGLHPYGPPPGMAL

DVL2

661

O14641
IAPPPPPGFGPHMFH

RBM22

371

Q9NW64
PPGFGPHMFHPMGPP

RBM22

376

Q9NW64
PMMPPYPGPGHCHQQ

LGALS4

161

P56470
PPPPHMVHYFHQQPP

FOXB2

171

Q5VYV0
PHHIMPPQQHYAPPP

CBLL1

331

Q75N03
HSPMCPPHCHMPPGP

MYO15B

11

Q96JP2
PYPHHQGGPPHCPPW

CHERP

441

Q8IWX8
PRGYLGPPHQGPPMH

CSTF2T

351

Q9H0L4
PPGPAPHPHPHPHAF

FOXD2

281

O60548
HPPMPPHPGHYWPVH

SMAD4

291

Q13485
GHPGMMPHQQPPPYP

SMARCC1

986

Q92922
HEPPPPPPMHGAGDA

WASF1

276

Q92558
PMNQGPHPPGHHGPP

SF1

431

Q15637
PHPPGHHGPPPMDQY

SF1

436

Q15637
SHPHPFPPGGMPHPG

SF3B4

291

Q15427
HGMRGPPPLMPPHGY

SF3B4

371

Q15427