Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	MYH1 MYH4 ABCA2 ATP7A HYOU1 ATRX SMC1A KIF1B ZNFX1 ACSF2 ABCB9 MACF1 DDX53 DDX24 ATP2B4	3.55e-05	614	143	15	GO:0140657
GeneOntologyMolecularFunction	calmodulin binding	MYH1 MYH4 MAP6 WFS1 UBR4 CASK ITPKC ATP2B4 IQGAP3	4.27e-05	230	143	9	GO:0005516
GeneOntologyMolecularFunction	nitrite reductase activity	MB CYGB CYB5R3	5.69e-05	11	143	3	GO:0098809
GeneOntologyMolecularFunction	oxidoreductase activity, acting on other nitrogenous compounds as donors	MB CYGB CYB5R3	2.27e-04	17	143	3	GO:0016661
GeneOntologyMolecularFunction	pantothenate kinase activity	PANK1 PANK2	3.03e-04	4	143	2	GO:0004594
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYH4 ABCA2 ATP7A ATRX SMC1A KIF1B ABCB9 MACF1 DDX53 DDX24 ATP2B4	3.41e-04	441	143	11	GO:0016887
GeneOntologyMolecularFunction	proteasome binding	WFS1 ECPAS SACS	3.75e-04	20	143	3	GO:0070628
GeneOntologyCellularComponent	axonemal central pair projection	CFAP69 HYDIN	4.26e-05	2	137	2	GO:1990718
GeneOntologyCellularComponent	lamellipodium membrane	DOCK8 EPHA2 FERMT2	3.87e-04	22	137	3	GO:0031258
GeneOntologyCellularComponent	somatodendritic compartment	FLNB ATP7A ANK3 RASGRF1 MAP6 WFS1 PCLO KIF1B ANKS1B CYGB SRR CLSTN1 CASK TXNRD1 SLC32A1 MET CLCN2 SACS CPEB1	4.19e-04	1228	137	19	GO:0036477
GeneOntologyCellularComponent	cone cell pedicle	PCLO SLC32A1	4.21e-04	5	137	2	GO:0044316
GeneOntologyCellularComponent	dendrite	ATP7A ANK3 RASGRF1 MAP6 WFS1 PCLO KIF1B ANKS1B CLSTN1 CASK SLC32A1 MET CLCN2 SACS CPEB1	5.14e-04	858	137	15	GO:0030425
GeneOntologyCellularComponent	dendritic tree	ATP7A ANK3 RASGRF1 MAP6 WFS1 PCLO KIF1B ANKS1B CLSTN1 CASK SLC32A1 MET CLCN2 SACS CPEB1	5.26e-04	860	137	15	GO:0097447
GeneOntologyCellularComponent	axonemal central apparatus	CFAP69 HYDIN	6.29e-04	6	137	2	GO:1990716
GeneOntologyCellularComponent	Golgi-associated vesicle	RAB12 ATP7A MAP6 PCLO SPPL2A	9.31e-04	114	137	5	GO:0005798
Domain	ANKS1	ANKS1B ANKS1A	5.66e-05	2	141	2	IPR033635
Domain	Myoglobin	MB CYGB	5.66e-05	2	141	2	IPR002335
Domain	IQ	MYH1 MYH4 RASGRF1 ADGB IQGAP3 IQUB	7.40e-05	93	141	6	PS50096
Domain	-	MB CYGB ADGB	1.14e-04	13	141	3	1.10.490.10
Domain	Globin/Proto	MB CYGB ADGB	1.14e-04	13	141	3	IPR012292
Domain	RNaseH-like_dom	KIAA1586 ESRP2 GTF2IRD2B GTF2IRD2 ZMYM6	1.74e-04	69	141	5	IPR012337
Domain	-	GTF2IRD2B GTF2IRD2	3.36e-04	4	141	2	3.90.1460.10
Domain	Myc_N	MYC MYCL	3.36e-04	4	141	2	PF01056
Domain	Type_II_PanK	PANK1 PANK2	3.36e-04	4	141	2	IPR004567
Domain	Tscrpt_reg_Myc_N	MYC MYCL	3.36e-04	4	141	2	IPR012682
Domain	Tscrpt_reg_Myc	MYC MYCL	3.36e-04	4	141	2	IPR002418
Domain	Fumble	PANK1 PANK2	3.36e-04	4	141	2	PF03630
Domain	GTF2I	GTF2IRD2B GTF2IRD2	3.36e-04	4	141	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	3.36e-04	4	141	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	3.36e-04	4	141	2	IPR004212
Domain	IQ	MYH1 MYH4 RASGRF1 ADGB IQGAP3	3.69e-04	81	141	5	SM00015
Domain	IQ_motif_EF-hand-BS	MYH1 MYH4 RASGRF1 ADGB IQGAP3	6.00e-04	90	141	5	IPR000048
Domain	P-loop_NTPase	RAB12 MYH1 MYH4 ABCA2 SAMD9 ATRX SMC1A KIF1B APAF1 ZNFX1 CASK ABCB9 DDX53 DDX24 HYDIN ARL14	6.76e-04	848	141	16	IPR027417
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GABRB2 FLNB ANK3 MAP6 WFS1 PCLO UBR4 NACA ANKS1B ZNFX1 BIRC6 LIN7A SACM1L MET CADPS CYB5R3 MACF1 PIP4K2B UQCRC2 CRYBG3 FERMT2 RASAL1	1.98e-09	1139	144	22	36417873
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ATP7A HYOU1 ANK3 ATRX WFS1 AHCTF1 UBR4 APAF1 FASTKD2 IKBIP CASK MRPL39 MET SACS EPHA2 MACF1 ERP29 UQCRC2 CRYBG3 FERMT2 DDX24 ATP2B4 EDRF1 SNX5	1.12e-08	1487	144	24	33957083
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNB HYOU1 ANK3 MAP6 DOCK8 WFS1 PCLO KIF1B ANKS1B ZNFX1 SACM1L CASK CERS5 GUCY1A2 SACS CADPS MACF1 MCAT UQCRC2 FERMT2 ATP2B4 HCK RASAL1	2.54e-08	1431	144	23	37142655
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RAB12 FLNB RIOK1 ATP7A HYOU1 ANK3 SMC1A AHCTF1 KIF1B ECPAS EPHA2 CYB5R3 MACF1 CRYBG3 FERMT2 ANKS1A	4.53e-08	708	144	16	39231216
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH1 FLNB MYH4 HYOU1 ATRX NSD2 PCLO MB UBR4 ANKS1B ATP5MK FER1L6 GTF2IRD2B ABCB9 GUCY1A2 SACS CYB5R3 GTF2IRD2 MACF1 PIP4K2B UQCRC2 CFAP69	1.31e-07	1442	144	22	35575683
Pubmed	skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration.	MYH4 MB NACA POSTN	2.73e-07	14	144	4	21071677
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB ABCA2 ANK3 ATRX KDM4C SMC1A KIF1B UBR4 NAP1L2 ANKS1B ZNFX1 CASK NAA25 WIZ SACS CADPS MACF1 MIGA1 ZMYM4 SNX5	3.78e-07	1285	144	20	35914814
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RIOK1 SAMD9 HYOU1 ATRX RPS6KB1 NACA ZNFX1 CLSTN1 SACM1L ZNF638 UQCRC2 CRYBG3 IQGAP3 CWF19L1	5.85e-07	650	144	14	38777146
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	FLNB AHCTF1 PCLO UBR4 APAF1 ECPAS CASK SACS CADPS MACF1 FERMT2 ANKS1A	1.22e-06	498	144	12	36634849
Pubmed	The SAM domains of Anks family proteins are critically involved in modulating the degradation of EphA receptors.	ANKS1B EPHA2 ANKS1A	1.38e-06	6	144	3	20100865
Pubmed	Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.	MYH1 HSPG2 MYH4	3.83e-06	8	144	3	26993635
Pubmed	CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation.	TSPAN15 UBE2R2 CDC34	3.83e-06	8	144	3	12037680
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ATRX SMC1A AHCTF1 BIRC6 IKBIP KMT2C NFKB1 ZNF638 HYDIN ZMYM4 ANKS1A	4.47e-06	469	144	11	27634302
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TDRD15 ATP7A ANK3 KIF1B BIRC6 CASK MET WIZ EPHA2 CYB5R3 ZNF638 MIEF1 FERMT2 ARL14	4.66e-06	777	144	14	35844135
Pubmed	Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation.	MYC LGR5 NFKB1	8.17e-06	10	144	3	28361920
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	MYC MYCL ESRRB KIF1B GRHL2 BIRC6 CERS5 MET KMT2C KLHL9 NFKB1 ZNF638 MACF1	8.60e-06	709	144	13	22988430
Pubmed	Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.	MYH1 MYH4 MB	1.12e-05	11	144	3	16024798
Pubmed	Extracellular matrix protein composition dynamically changes during murine forelimb development.	MYH1 HSPG2 MYH4	1.12e-05	11	144	3	38303699
Pubmed	Tagging genes with cassette-exchange sites.	FLNB UBR4 BIRC6 KMT2C CYB5R3 MACF1 PIP4K2B ZMYM4 SNX5	1.17e-05	335	144	9	15741177
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB ANK3 ATRX NSD2 RPS6KB1 KIF1B ECPAS GRHL2 LRRC8D DENND2B CASK KMT2C KLHL9 PCNX4 ZNF638 MACF1 CFAP69 ZMYM4 ANKS1A	1.33e-05	1489	144	19	28611215
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HYOU1 ANK3 AHCTF1 EPHA2 ZNF638 MACF1 CRYBG3 ANKS1A	1.49e-05	263	144	8	34702444
Pubmed	Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb.	FLNB SMC1A KIF1B NFKB1	1.50e-05	36	144	4	22421546
Pubmed	Estrogen and Myc negatively regulate expression of the EphA2 tyrosine kinase.	MYC EPHA2	1.70e-05	2	144	2	11968011
Pubmed	The Oncogenic Protein Kinase/ATPase RIOK1 Is Up-Regulated via the c-myc/E2F Transcription Factor Axis in Prostate Cancer.	MYC RIOK1	1.70e-05	2	144	2	37301535
Pubmed	MicroRNA profiling in ocular adnexal lymphoma: a role for MYC and NFKB1 mediated dysregulation of microRNA expression in aggressive disease.	MYC NFKB1	1.70e-05	2	144	2	23821202
Pubmed	MYCL1 Amplification and Expression of L-Myc and c-Myc in Surgically Resected Small-Cell Lung Carcinoma.	MYC MYCL	1.70e-05	2	144	2	34257619
Pubmed	ZNFX1 anti-sense RNA 1 promotes the tumorigenesis of prostate cancer by regulating c-Myc expression via a regulatory network of competing endogenous RNAs.	MYC ZNFX1	1.70e-05	2	144	2	31321444
Pubmed	Solution structure of the first Sam domain of Odin and binding studies with the EphA2 receptor.	EPHA2 ANKS1A	1.70e-05	2	144	2	22332920
Pubmed	EBP1 suppresses growth, migration, and invasion of thyroid cancer cells through upregulating RASAL expression.	NFKB1 RASAL1	1.70e-05	2	144	2	26008146
Pubmed	Role of Periostin and Nuclear Factor-κB Interplay in the Development of Diabetic Nephropathy.	POSTN NFKB1	1.70e-05	2	144	2	35883655
Pubmed	Growth and muscle defects in mice lacking adult myosin heavy chain genes.	MYH1 MYH4	1.70e-05	2	144	2	9382868
Pubmed	Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.	MYH1 MYH4	1.70e-05	2	144	2	11150240
Pubmed	c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells.	MYC NFKB1	1.70e-05	2	144	2	28232371
Pubmed	Tumor-Specific Effector CD8+ T Cells That Can Establish Immunological Memory in Humans after Adoptive Transfer Are Marked by Expression of IL7 Receptor and c-myc.	MYC IL7R	1.70e-05	2	144	2	26100671
Pubmed	Exome sequencing identified rare variants in genes HSPG2 and ATP2B4 in a family segregating developmental dysplasia of the hip.	HSPG2 ATP2B4	1.70e-05	2	144	2	28327142
Pubmed	Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.	EPHA2 ANKS1A	1.70e-05	2	144	2	26120079
Pubmed	Comparative study on the mutation spectrum of L-MYC and C-MYC genes of blood cfDNA in patients with ovarian cancer and healthy females.	MYC MYCL	1.70e-05	2	144	2	37827180
Pubmed	Imidazo [4,5f][1,10] phenanthroline derivatives as inhibitor of c-myc gene expression in A549 cells via NF-κB pathway.	MYC NFKB1	1.70e-05	2	144	2	22172699
Pubmed	L-myc gene polymorphism and risk of thyroid cancer.	MYC MYCL	1.70e-05	2	144	2	18566574
Pubmed	UBR4/POE facilitates secretory trafficking to maintain circadian clock synchrony.	UBR4 SLC32A1	1.70e-05	2	144	2	35332162
Pubmed	MET and MYC cooperate in mammary tumorigenesis.	MYC MET	1.70e-05	2	144	2	15738393
Pubmed	Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.	RPS6KB1 NFKB1	1.70e-05	2	144	2	19433583
Pubmed	Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes.	LIN7A CASK	1.70e-05	2	144	2	12110687
Pubmed	Regulation of c-myc gene by nitric oxide via inactivating NF-kappa B complex in P19 mouse embryonal carcinoma cells.	MYC NFKB1	1.70e-05	2	144	2	12783888
Pubmed	MYCL promotes iPSC-like colony formation via MYC Box 0 and 2 domains.	MYC MYCL	1.70e-05	2	144	2	34930932
Pubmed	A therapeutic approach to pantothenate kinase associated neurodegeneration.	PANK1 PANK2	1.70e-05	2	144	2	30352999
Pubmed	WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating.	MYC AHCTF1	1.70e-05	2	144	2	31784729
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.70e-05	2	144	2	15388857
Pubmed	Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop.	NSD2 NFKB1	1.70e-05	2	144	2	22645312
Pubmed	Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.	MYH1 MYH4	1.70e-05	2	144	2	11744674
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	SDK2 ATP7A HYOU1 AHCTF1 RPS6KB1 NACA IKBIP WIZ CYB5R3 MIEF1 ERP29 FERMT2 CWF19L1 ZMYM4 SNX5	2.01e-05	1007	144	15	34597346
Pubmed	Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.	MYH1 MYH4 MB	2.45e-05	14	144	3	27184118
Pubmed	Mitochondrial Raf1 Regulates Glutamine Catabolism.	SAMD9 ANK3 ADGB NAA25 ERP29 UQCRC2 ATP2B4 SNX5	2.85e-05	288	144	8	38496616
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNB ABCA2 HYOU1 ANK3 PCLO RPS6KB1 UBR4 ECPAS TXNRD1 MACF1 ERP29 IQGAP3 HYDIN	3.32e-05	807	144	13	30575818
Pubmed	MusTRD can regulate postnatal fiber-specific expression.	MYH1 MYH4 MB	3.74e-05	16	144	3	16494860
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	ATRX SMC1A ECPAS GRHL2 KMT2C WIZ ZMYM4	3.89e-05	220	144	7	35785414
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	RAB12 HYOU1 WFS1 ECPAS PIP4K2B SESN2	3.98e-05	150	144	6	32423001
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FLNB HYOU1 ANK3 ATRX MAP6 AHCTF1 RPS6KB1 IKBIP KMT2C UBE2R2 ZNF638 MACF1 ERP29 FERMT2 SNX5	4.66e-05	1084	144	15	11544199
Pubmed	Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.	MYH1 MYH4	5.09e-05	3	144	2	26059207
Pubmed	Efficient Reduction of Vertebrate Cytoglobins by the Cytochrome b5/Cytochrome b5 Reductase/NADH System.	CYGB CYB5R3	5.09e-05	3	144	2	28671819
Pubmed	Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.	MYH1 MYH4	5.09e-05	3	144	2	36515178
Pubmed	Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.	PANK1 PANK2	5.09e-05	3	144	2	17379144
Pubmed	Cloning and mapping of members of the MYM family.	ZMYM4 ZMYM6	5.09e-05	3	144	2	10486218
Pubmed	qPCR Analysis Reveals Association of Differential Expression of SRR, NFKB1, and PDE4B Genes With Type 2 Diabetes Mellitus.	SRR NFKB1	5.09e-05	3	144	2	35046895
Pubmed	Interaction of the plasma membrane Ca2+ pump 4b/CI with the Ca2+/calmodulin-dependent membrane-associated kinase CASK.	CASK ATP2B4	5.09e-05	3	144	2	12511555
Pubmed	Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain.	MB CYGB	5.09e-05	3	144	2	16899760
Pubmed	MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities.	MYC MET	5.09e-05	3	144	2	36433941
Pubmed	Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription.	MYC RPS6KB1	5.09e-05	3	144	2	27385002
Pubmed	Tissue and age specific expression of the myc proto-oncogene family throughout the life span of the C57BL/6J mouse strain.	MYC MYCL	5.09e-05	3	144	2	2470008
Pubmed	Transition from cMyc to L-Myc during dendritic cell development coordinated by rising levels of IRF8.	MYC MYCL	5.09e-05	3	144	2	34958351
Pubmed	Identification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling function.	ANKS1B ANKS1A	5.09e-05	3	144	2	17875921
Pubmed	The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation.	MYC RPS6KB1	5.09e-05	3	144	2	25220053
Pubmed	ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.	ANKS1B ANKS1A	5.09e-05	3	144	2	38123547
Pubmed	Proteomic profile identifies dysregulated pathways in Cornelia de Lange syndrome cells with distinct mutations in SMC1A and SMC3 genes.	MYC SMC1A	5.09e-05	3	144	2	23106691
Pubmed	Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma.	MYC MET	5.09e-05	3	144	2	18059365
Pubmed	Cutting edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cells.	MYC IL7R	5.09e-05	3	144	2	23420891
Pubmed	Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.	EPHA2 ANKS1A	5.09e-05	3	144	2	29749928
Pubmed	Antiproliferative protein Tob directly regulates c-myc proto-oncogene expression through cytoplasmic polyadenylation element-binding protein CPEB.	MYC CPEB1	5.09e-05	3	144	2	23178487
Pubmed	ADGB variants cause asthenozoospermia and male infertility.	ADGB CFAP69	5.09e-05	3	144	2	36995441
Pubmed	Inhibition of KDM4C/c-Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism.	MYC KDM4C	5.09e-05	3	144	2	35343073
Pubmed	EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer.	MYC EPHA2	5.09e-05	3	144	2	30451837
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	5.09e-05	3	144	2	15100712
Pubmed	Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development.	LIN7A CASK	5.09e-05	3	144	2	16688213
Pubmed	Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo.	MYC LGR5	5.09e-05	3	144	2	22884366
Pubmed	TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling.	TSPAN15 NFKB1	5.09e-05	3	144	2	29650964
Pubmed	Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site.	MYC AHCTF1	5.09e-05	3	144	2	35017527
Pubmed	Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.	PANK1 PANK2	5.09e-05	3	144	2	17631502
Pubmed	Compartmentalization of mammalian pantothenate kinases.	PANK1 PANK2	5.09e-05	3	144	2	23152917
Pubmed	Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC.	MYC IL7R	5.09e-05	3	144	2	38031763
Pubmed	CASK interacts with PMCA4b and JAM-A on the mouse sperm flagellum to regulate Ca2+ homeostasis and motility.	CASK ATP2B4	5.09e-05	3	144	2	22020416
Pubmed	Androgen receptor and c-Myc transcription factors as putative partners in the in vivo cross-talk between androgen receptor-mediated and c-Met-mediated signalling pathways.	MYC MET	5.09e-05	3	144	2	17520086
Pubmed	B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent induction of Rel/NF-kappaB regulated c-myc transcription.	MYC NFKB1	5.09e-05	3	144	2	12504005
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	SMC1A ESRRB GRHL2 KMT2C WIZ ZMYM4	7.22e-05	167	144	6	20362541
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ABCA2 SDK2 NSD2 NACA FASTKD2 ECPAS KMT2C KLHL9 ZMYM4 ANKS1A	7.59e-05	529	144	10	14621295
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MYC MYH4 CYP4F8 HYOU1 ATRX SMC1A KIF1B UBR4 ECPAS MET KMT2C NAA25 PANK2 UQCRC2 DDX24 ANKS1A	8.86e-05	1284	144	16	17353931
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNB RIOK1 HYOU1 ATRX NSD2 SMC1A PCLO UBR4 NACA FASTKD2 ECPAS SACM1L CYB5R3 ERP29 UQCRC2 DDX24 IQGAP3	8.95e-05	1425	144	17	30948266
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNB HYOU1 NSD2 AHCTF1 UBR4 ECPAS BIRC6 ZNF638 MACF1 UQCRC2 DDX24	9.23e-05	653	144	11	22586326
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	TSPAN15 CAAP1 ATP7A HYOU1 ANK3 SMC1A RPS6KB1 KIF1B LIPF ANKS1B ZNF571 LRRC8D POSTN KMT2C ZNF638 HYDIN	9.60e-05	1293	144	16	15342556
Pubmed	ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization.	ANKS1B CASK	1.02e-04	4	144	2	26085624
Pubmed	Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.	PANK1 PANK2	1.02e-04	4	144	2	22815849
Interaction	DNAJC5 interactions	ATP7A ANK3 LIN7A CASK SLC32A1 MET CADPS EPHA2 MACF1 FERMT2 ATP2B4 EDRF1 SNX5	3.08e-06	378	143	13	int:DNAJC5
Interaction	CASK interactions	MYC MYCL KIF1B LIN7A CASK EPHA2 PIP4K2B ATP2B4 HCK ARL14	4.11e-06	221	143	10	int:CASK
Interaction	STAG3L4 interactions	TSPAN15 IKBIP ZMYM6	1.20e-05	7	143	3	int:STAG3L4
Interaction	KCNA3 interactions	RAB12 FLNB RIOK1 ATP7A HYOU1 ANK3 SMC1A AHCTF1 KIF1B NACA ECPAS KMT2C EPHA2 CYB5R3 MACF1 CRYBG3 FERMT2 IQGAP3 ANKS1A	1.32e-05	871	143	19	int:KCNA3
Interaction	GUCY1B1 interactions	ABCA2 LIN7A CASK GUCY1A2 PIP4K2B	2.02e-05	47	143	5	int:GUCY1B1
Cytoband	12q23-q24.1	NACA TXNRD1	1.45e-04	6	144	2	12q23-q24.1
GeneFamily	Zinc fingers MYM-type	ZMYM4 ZMYM6	4.48e-04	6	100	2	86
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	MYC FLNB ATRX AVL9 KDM4C AHCTF1 DENND2B CASK TXNRD1 SACS NFKB1 ZNF638 MACF1 CRYBG3 FERMT2 ATP2B4 ZMYM4 IL7R ANKS1A	2.50e-07	856	144	19	M4500
Coexpression	GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP	AVL9 RPS6KB1 NACA LRRC8D SACS MACF1 UQCRC2 CDC34	1.55e-05	200	144	8	M3271
Coexpression	GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP	RIOK1 RASGRF1 RPS6KB1 KIF1B UBR4 SACM1L TXNRD1 RASAL1	1.55e-05	200	144	8	M7135
Coexpression	GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP	FLNB ATP7A ANK3 PCLO IKBIP TXNRD1 ESRP2 IL7R	1.55e-05	200	144	8	M9060
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	GABRB2 ANK3 ATRX KIF1B APAF1 DTX3L ECPAS LGR5 CASK SPPL2A MIGA1 FERMT2 ZMYM4	1.34e-06	369	143	13	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	GABRB2 MYH1 HYOU1 AVL9 SLC38A4 APAF1 NAP1L2 IKBIP IGDCC4 CASK POSTN PIEZO2 CLCN2 HMCN1 CADPS SESN2 HCK ZMYM6 SENP7	1.57e-06	791	143	19	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	GABRB2 MYCL ANK3 ATRX KIF1B APAF1 NAP1L2 DTX3L ECPAS IFI16 LGR5 CASK ESRP2 SPPL2A TC2N HMCN1 MIGA1 FERMT2 ZMYM4	2.07e-06	806	143	19	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500	RAB12 ATP7A ATRX SMC1A KIF1B LGR5 BIRC6 PANK1 TXNRD1 KATNBL1 CPEB1	9.24e-05	403	143	11	gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	RAB12 ATP7A ATRX TLCD4 LGR5 BIRC6 PANK1 KMT2C KATNBL1 SPPL2A TC2N HMCN1 SACS ZMYM6 SENP7 CPEB1	9.32e-05	795	143	16	gudmap_developingGonad_e16.5_ovary_1000
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SAMD9 ATRX DOCK8 DTX3L IFI16 BIRC6 KMT2C MACF1 DDX24	1.92e-08	200	144	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 NSD2 ANKRD36C FER1L6 ITPKC TC2N EPHA2 MACF1	1.27e-07	179	144	8	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF1 TLCD4 ESRRB PIEZO2 MDH1B HYDIN FRMD5 IQUB	1.71e-07	186	144	8	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ATRX AVL9 SMC1A KIF1B BIRC6 MIGA1 CRYBG3 ZMYM4	2.27e-07	193	144	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNB ATRX IFI16 BIRC6 KMT2C HMCN1 MACF1 IL7R	2.97e-07	200	144	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 SLC38A4 PCLO FASTKD2 MET PIEZO2 TC2N	1.68e-06	175	144	7	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 DTX3L ATP5MK ECPAS PCNX4 MACF1 ATP2B4	1.81e-06	177	144	7	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 DTX3L ATP5MK ECPAS PCNX4 MACF1 ATP2B4	1.81e-06	177	144	7	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	SAMD9 DTX3L ATP5MK ECPAS PCNX4 MACF1 ATP2B4	1.81e-06	177	144	7	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SAMD9 DTX3L ATP5MK ECPAS PCNX4 MACF1 ATP2B4	1.81e-06	177	144	7	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SAMD9 DTX3L ATP5MK ECPAS PCNX4 MACF1 ATP2B4	1.81e-06	177	144	7	d5aeda113afaa2425874394610344570c9078478
ToppCell	facs-SCAT-Fat-3m-Epithelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL ANK3 RASGRF1 TLCD4 GRHL2 ESRP2 PIEZO2	2.60e-06	187	144	7	08f2ecce3c08f35d995187b21bb7407a99dee4c2
ToppCell	facs-SCAT-Fat-3m-Epithelial-epithelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL ANK3 RASGRF1 TLCD4 GRHL2 ESRP2 PIEZO2	2.60e-06	187	144	7	939a068ac0913b9eeb5da4a9cb267d51cb711999
ToppCell	facs-SCAT-Fat-3m-Epithelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL ANK3 RASGRF1 TLCD4 GRHL2 ESRP2 PIEZO2	2.60e-06	187	144	7	e02e7f608506b9a48384f07727944f1cb8f7c575
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9 ANK3 ZNFX1 DTX3L IFI16 NAA25 IL7R	2.70e-06	188	144	7	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7A POSTN GUCY1A2 SESN2 FERMT2 ATP2B4 CPEB1	2.89e-06	190	144	7	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB SDK2 RASGRF1 WFS1 PCLO CADPS CPEB1	3.10e-06	192	144	7	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ANK3 ANKRD36C KMT2C TC2N NFKB1 MACF1 IL7R	3.10e-06	192	144	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB HYOU1 WFS1 PCLO KIF1B UBR4 CPEB1	3.21e-06	193	144	7	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB HYOU1 WFS1 PCLO KIF1B UBR4 CADPS	3.21e-06	193	144	7	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	PBMC-Mild-cDC_1\|Mild / Compartment, Disease Groups and Clusters	SAMD9 DOCK8 DTX3L ATP5MK IFI16 CRYBG3 DDX24	3.43e-06	195	144	7	674355ca00314bde90ef7f6ddb83afe2d5323130
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB MAP6 LGR5 IGDCC4 POSTN HMCN1 MACF1	3.55e-06	196	144	7	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	frontal_cortex-Neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANK3 PCLO NAP1L2 ANKS1B CLSTN1 ST8SIA3 CADPS	3.55e-06	196	144	7	de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 KDM4C ANKRD36C KMT2C TC2N MACF1 DDX24	3.67e-06	197	144	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYC ANK3 CASK TC2N LPAR6 DDX24 IL7R	3.80e-06	198	144	7	b0b0977d9482538a076b84a8dc8b15ed682662f9
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	MYC SAMD9 ATRX ANKRD36C TC2N DDX24 IL7R	3.92e-06	199	144	7	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD4+_Tcm\|COVID-19_Convalescent / Disease, condition lineage and cell class	MYC TSPAN15 ANK3 TC2N LPAR6 DDX24 IL7R	4.06e-06	200	144	7	99c5abfe96d791c60ae6021ab4201851ee4afc47
ToppCell	severe_influenza-CD4+_T_naive\|World / disease group, cell group and cell class (v2)	MYC HSPG2 CYP4F8 ANK3 ALOX12B IL7R	1.27e-05	158	144	6	8ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCell	severe_influenza-CD4+_T_naive\|severe_influenza / disease group, cell group and cell class (v2)	MYC HSPG2 CYP4F8 ANK3 ALOX12B IL7R	1.27e-05	158	144	6	ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYC ATP7A WFS1 DENND2B GUCY1A2 SACS	1.42e-05	161	144	6	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYC ATP7A WFS1 DENND2B GUCY1A2 SACS	1.42e-05	161	144	6	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4\|Lung / Manually curated celltypes from each tissue	ANK3 MAP6 ADGB CFAP69 ALOX12B IQUB	1.47e-05	162	144	6	91cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell	COVID-19_Severe-CD4+_T_activated\|COVID-19_Severe / Disease condition and Cell class	MYC SAMD9 ANK3 DTX3L IFI16 IL7R	1.69e-05	166	144	6	0f138dbafad6f83975944e8f6398411127b150cc
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AHCTF1 ANKRD36C TC2N SACS ATP2B4 IL7R	1.74e-05	167	144	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	15-Airway-Epithelial-Club-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	MYCL GRHL2 ESRP2 MET EPHA2 ARL14	1.93e-05	170	144	6	1418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8 POSTN PIEZO2 GUCY1A2 CADPS FERMT2	2.27e-05	175	144	6	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 SLC32A1 MDH1B GTF2IRD2 PIP4K2B HYDIN	2.50e-05	178	144	6	6178706db4a855d72abc156537604d575624df56
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 SLC32A1 MDH1B GTF2IRD2 PIP4K2B HYDIN	2.50e-05	178	144	6	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9 ANK3 ZNFX1 DTX3L IFI16 NAA25	2.58e-05	179	144	6	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	facs\|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYC CLSTN1 LGR5 ESRP2 POSTN CYB5R3	2.58e-05	179	144	6	8001db3044e8657980e24422377c4fdb0d7b323e
ToppCell	ASK454-Epithelial-Ciliated\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	CYGB GRHL2 ADGB GTF2IRD2B MDH1B HYDIN	2.58e-05	179	144	6	f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SDK2 CYGB DENND2B POSTN PIEZO2 GUCY1A2	2.58e-05	179	144	6	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	ANK3 ANKRD36C TC2N NFKB1 MACF1 IL7R	2.75e-05	181	144	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TSPAN15 HSPG2 WFS1 PIEZO2 HMCN1 EPHA2	2.83e-05	182	144	6	997d37ca2af661c92a56add888762724dfccc890
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 MYH1 PCLO PIEZO2 HMCN1 HYDIN	3.01e-05	184	144	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX DOCK8 BIRC6 ZNF638 MACF1 IL7R	3.01e-05	184	144	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 MYH1 PCLO PIEZO2 HMCN1 HYDIN	3.01e-05	184	144	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 MYH1 PCLO PIEZO2 HMCN1 HYDIN	3.01e-05	184	144	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYC CYP4F8 TC2N LPAR6 IL7R SENP7	3.10e-05	185	144	6	e34473eea3a58c041183a4f52137366cd9489495
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A SLC38A4 ACSF2 CLSTN1 TC2N EPHA2	3.10e-05	185	144	6	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.10e-05	185	144	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TSPAN15 HSPG2 WFS1 PIEZO2 HMCN1 EPHA2	3.20e-05	186	144	6	e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.20e-05	186	144	6	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	AVL9 DOCK8 AHCTF1 ANKRD36C BIRC6 MACF1	3.20e-05	186	144	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.20e-05	186	144	6	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	AHCTF1 ANKRD36C BIRC6 KMT2C NFKB1 MACF1	3.40e-05	188	144	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	GABRB2 ANK3 RASGRF1 PCLO GRHL2 DENND2B	3.40e-05	188	144	6	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Leuk-UTI-Lymphocyte-T_NK-CD4_TCM\|Leuk-UTI / Disease, Lineage and Cell Type	MYC ANK3 TC2N LPAR6 DDX24 IL7R	3.60e-05	190	144	6	5f8d606d2f465ddeae7451835f84b3f25a151d2a
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	WFS1 SLC38A4 PCLO PIEZO2 TC2N ANKS1A	3.60e-05	190	144	6	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	GABRB2 ANK3 PCLO ST8SIA3 SLC32A1 NPFFR2	3.60e-05	190	144	6	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SAMD9 ANK3 IFI16 LPAR6 DDX24 IL7R	3.60e-05	190	144	6	f6616b3fe7f4962249503c96c06926240066d861
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.71e-05	191	144	6	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL ANK3 RASGRF1 TLCD4 ESRRB PIEZO2	3.71e-05	191	144	6	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 RASGRF1 GRHL2 MET TC2N EPHA2	3.71e-05	191	144	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.71e-05	191	144	6	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	HYOU1 AHCTF1 ANKRD36C BIRC6 MACF1 EDRF1	3.71e-05	191	144	6	9454f642c3621370fa23640b631301346b300950
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.71e-05	191	144	6	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYC TSPAN15 ANK3 CASK TC2N IL7R	3.71e-05	191	144	6	9c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ANK3 RASGRF1 PCLO GRHL2 MET FRMD5	3.71e-05	191	144	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.71e-05	191	144	6	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB WFS1 SLC38A4 PCLO CADPS CPEB1	3.71e-05	191	144	6	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	3.71e-05	191	144	6	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	COVID-19-Lymphoid-pDC\|COVID-19 / Condition, Lineage and Cell class	MYCL HSPG2 SDK2 SIDT1 SLC32A1 EPHA2	3.71e-05	191	144	6	25343b11d42128ad16659e5519cd1673266cc505
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	ANK3 GRHL2 MET EPHA2 CFAP69 HYDIN	3.82e-05	192	144	6	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	WFS1 SLC38A4 PCLO CASK PIEZO2 TC2N	3.82e-05	192	144	6	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	WFS1 SLC38A4 PCLO CASK PIEZO2 TC2N	3.82e-05	192	144	6	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MYC SAMD9 ANK3 TC2N LPAR6 IL7R	3.82e-05	192	144	6	e07b6892276c81c1227e94ca942f6820d89a7ca3
ToppCell	COVID-19_Severe-CD4+_Tcm\|World / disease group, cell group and cell class	MYC ANK3 CASK TC2N LPAR6 IL7R	3.82e-05	192	144	6	3352f13a6e706991dcf3ec173587bb6aba36a385
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYCL PCLO GRHL2 MET TC2N RASAL1	3.82e-05	192	144	6	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	MYCL MAP6 MB ADGB EPHA2 HYDIN	3.82e-05	192	144	6	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX NSD2 UBR4 PIEZO2 MACF1 HYDIN	3.82e-05	192	144	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	COVID-19_Moderate-CD4+_T_activated\|World / disease group, cell group and cell class	MYC SAMD9 ANK3 TC2N DDX24 IL7R	3.93e-05	193	144	6	c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MYC HSPG2 IFI16 POSTN MET LPAR6	3.93e-05	193	144	6	e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCell	facs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB LGR5 IGDCC4 POSTN HMCN1 MACF1	3.93e-05	193	144	6	eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANK3 DENND2B ADGB CFAP69 HYDIN IQUB	3.93e-05	193	144	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 KDM4C ANKRD36C TC2N MACF1 DDX24	3.93e-05	193	144	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB ANK3 SIDT1 ACSF2 ITPKC EPHA2	3.93e-05	193	144	6	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MYC HSPG2 IFI16 POSTN MET LPAR6	3.93e-05	193	144	6	b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCell	COVID-19_Severe-CD4+_Tcm\|COVID-19_Severe / disease group, cell group and cell class	MYC ANK3 CASK TC2N LPAR6 IL7R	3.93e-05	193	144	6	45fe14c10b71459047608c8931d83c9c533f97f9
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MYC SAMD9 ANK3 TC2N LPAR6 IL7R	4.05e-05	194	144	6	0b0042b6a356a49a059fb64a1e1abb25c82d48cf
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	4.05e-05	194	144	6	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	Severe-CD4+_T\|World / Disease group and Cell class	MYC TSPAN15 ANK3 NACA LPAR6 IL7R	4.05e-05	194	144	6	2ad888f78765ecfb8d1ea978c75c90fa3030509a
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB LGR5 IGDCC4 POSTN HMCN1 MACF1	4.05e-05	194	144	6	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	Differ-Basal\|World / shred by cell class for mouse tongue	TSPAN15 ANK3 DOCK8 CYGB BCO1 ESRP2	4.05e-05	194	144	6	851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MYC ANK3 ANKRD36C TC2N MACF1 IL7R	4.16e-05	195	144	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX PCLO KIF1B KMT2C CADPS MACF1	4.16e-05	195	144	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYCL FLNB NACA SIDT1 EPHA2 ERP29	4.16e-05	195	144	6	06051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAP6 ADGB MDH1B CFAP69 HYDIN IQUB	4.16e-05	195	144	6	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYCL FLNB NACA SIDT1 EPHA2 ERP29	4.16e-05	195	144	6	3aa44633c72658545aa2b35bf9d532c62f36a451
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MYC ANK3 ANKRD36C TC2N LPAR6 IL7R	4.16e-05	195	144	6	22191d361af136942508f1553ff41a626ed982ad
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SMC1A AHCTF1 ZNF638 MACF1 ZMYM4	4.92e-05	50	87	5	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drug	Hycanthone [3105-97-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	MYC ANK3 AVL9 SIDT1 NAP1L2 ZNF571 MET KLHL9 PIP4K2B ATP2B4 ZMYM6	3.04e-08	188	143	11	5691_DN
Drug	AC1N9ZZC	MYH1 HSPG2 MYH4 ANK3 SIDT1 DENND2B SLC32A1 FERMT2 ALOX12B	4.37e-07	149	143	9	CID004369374
Drug	1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one	HSPG2 FLNB NAP1L2 ANKS1B ST8SIA3 DENND2B IGDCC4 TXNRD1 SLC32A1 CADPS EPHA2 SESN2 CPEB1	6.99e-07	373	143	13	ctd:C540355
Drug	geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A	HYOU1 AVL9 NACA NAP1L2 CFAP69 EDRF1 IL7R CPEB1	2.37e-05	186	143	8	1228_UP
Drug	17-AAG; Up 200; 1uM; PC3; HT_HG-U133A	KDM4C NACA NAP1L2 FASTKD2 ECPAS CFAP69 IL7R CPEB1	2.46e-05	187	143	8	1218_UP
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; HL60; HT_HG-U133A	MYCL SAMD9 KDM4C NSD2 SMC1A ZNF571 IFI16 MACF1	3.32e-05	195	143	8	2355_DN
Drug	Dimethadione [695-53-4]; Up 200; 31uM; MCF7; HT_HG-U133A	MYCL ABCA2 PCLO ANKS1B ST8SIA3 LIN7A CFAP69 EDRF1	3.45e-05	196	143	8	5668_UP
Drug	Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A	HSPG2 ABCA2 KDM4C LIN7A ABCB9 PIP4K2B ZMYM6 SENP7	3.57e-05	197	143	8	6095_DN
Drug	Allantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A	GABRB2 ABCA2 KDM4C LIN7A BCO1 MET ABCB9 ATP2B4	3.57e-05	197	143	8	1678_UP
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MYCL SIDT1 ITPKC WIZ EPHA2 ATP2B4 ZMYM6 RASAL1	3.57e-05	197	143	8	3308_DN
Drug	Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A	GABRB2 MYCL HSPG2 KDM4C SMC1A MET WIZ ZMYM6	3.57e-05	197	143	8	3575_DN
Drug	SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A	HSPG2 ATRX AVL9 KDM4C SACS PCNX4 PIP4K2B ANKS1A	3.70e-05	198	143	8	6915_UP
Drug	Glipizide [29094-61-9]; Down 200; 9uM; PC3; HT_HG-U133A	HSPG2 SMC1A MB MET ABCB9 CFAP69 CWF19L1 SENP7	3.84e-05	199	143	8	6645_DN
Drug	l3 g	MCAT HCK	3.92e-05	2	143	2	CID009549185
Drug	Ketamine	MYC GABRB2 CAAP1 ATP7A RASGRF1 MAP6 WFS1 PANK1 DENND2B IKBIP SLC32A1 MSANTD3 KLHL9 CYB5R3 ZNF638 SENP7	4.32e-05	798	143	16	ctd:D007649
Disease	Neuroblastoma	MYC ATRX DOCK8 KIF1B MET	2.92e-06	47	140	5	C0027819
Disease	Colorectal Carcinoma	MYC RPS6KB1 LGR5 TXNRD1 POSTN KMT2C GUCY1A2 SACS SESN2 UQCRC2 EDRF1 ZMYM4 IQUB	3.16e-05	702	140	13	C0009402
Disease	myopathy (implicated_via_orthology)	MYH1 FLNB MYH4 CLCN2	8.03e-05	48	140	4	DOID:423 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	GABRB2 DOCK8 SMC1A CASK KMT2C	8.32e-05	93	140	5	C1535926
Disease	pantothenate kinase-associated neurodegeneration (implicated_via_orthology)	PANK1 PANK2	1.33e-04	4	140	2	DOID:3981 (implicated_via_orthology)
Disease	sarcoma (is_marker_for)	ATRX MET	2.21e-04	5	140	2	DOID:1115 (is_marker_for)
Disease	Carcinoma, Granular Cell	MYC MET KMT2C NFKB1 ALOX12B	2.35e-04	116	140	5	C0205644
Disease	Adenocarcinoma, Tubular	MYC MET KMT2C NFKB1 ALOX12B	2.35e-04	116	140	5	C0205645
Disease	Adenocarcinoma, Oxyphilic	MYC MET KMT2C NFKB1 ALOX12B	2.35e-04	116	140	5	C0205642
Disease	Carcinoma, Cribriform	MYC MET KMT2C NFKB1 ALOX12B	2.35e-04	116	140	5	C0205643
Disease	Adenocarcinoma, Basal Cell	MYC MET KMT2C NFKB1 ALOX12B	2.35e-04	116	140	5	C0205641
Disease	Adenocarcinoma	MYC MET KMT2C NFKB1 ALOX12B	2.35e-04	116	140	5	C0001418
Disease	azoospermia (implicated_via_orthology)	ESRRB UBE2R2 CDC34	2.81e-04	27	140	3	DOID:14227 (implicated_via_orthology)
Disease	Hematopoetic Myelodysplasia	MYC SAMD9 ATRX	3.49e-04	29	140	3	C2713368
Disease	stem Cell Growth Factor beta measurement	KDM4C ANKS1B TXNRD1 PIEZO2	4.54e-04	75	140	4	EFO_0008292
Disease	Colonic Neoplasms	MYC ATP7A LGR5 NFKB1 ALOX12B	8.10e-04	152	140	5	C0009375
Disease	calcium measurement	SLC38A4 SIDT1 DTX3L SPPL2A TC2N PCNX4 CYB5R3 MACF1 MIGA1 SENP7	8.58e-04	628	140	10	EFO_0004838
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH4	9.81e-04	10	140	2	DOID:0080326 (implicated_via_orthology)
Disease	Malignant tumor of colon	MYC ATP7A LGR5 NFKB1 ALOX12B	9.91e-04	159	140	5	C0007102
Disease	Secondary Biliary Cholangitis	CYGB NFKB1 IL7R	1.05e-03	42	140	3	C0238065
Disease	Biliary cirrhosis	CYGB NFKB1 IL7R	1.05e-03	42	140	3	C0023892
Disease	Biliary Cirrhosis, Primary, 1	CYGB NFKB1 IL7R	1.05e-03	42	140	3	C4551595
Disease	autistic disorder (is_implicated_in)	GABRB2 KDM4C MET	1.05e-03	42	140	3	DOID:12849 (is_implicated_in)
Disease	primary immunodeficiency disease (is_implicated_in)	ZNFX1 SPPL2A IL7R	1.05e-03	42	140	3	DOID:612 (is_implicated_in)
Disease	Childhood Medulloblastoma	MYC MYCL KDM4C	1.12e-03	43	140	3	C0278510
Disease	Melanotic medulloblastoma	MYC MYCL KDM4C	1.12e-03	43	140	3	C1275668
Disease	Medullomyoblastoma	MYC MYCL KDM4C	1.12e-03	43	140	3	C0205833
Disease	Desmoplastic Medulloblastoma	MYC MYCL KDM4C	1.12e-03	43	140	3	C0751291
Disease	Adult Medulloblastoma	MYC MYCL KDM4C	1.12e-03	43	140	3	C0278876
Disease	complement C1q tumor necrosis factor-related protein 5 measurement	APAF1 IKBIP	1.20e-03	11	140	2	EFO_0801494
Disease	trypsin-3 measurement	GRHL2 UBE2R2	1.20e-03	11	140	2	EFO_0020791
Disease	biliary liver cirrhosis	NFKB1 ARL14 IL7R	1.20e-03	44	140	3	EFO_0004267
Disease	lung non-small cell carcinoma (is_marker_for)	NSD2 APAF1 MET NFKB1 IL7R	1.30e-03	169	140	5	DOID:3908 (is_marker_for)
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH4	1.43e-03	12	140	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH4	1.43e-03	12	140	2	DOID:2106 (implicated_via_orthology)
Disease	Primary biliary cirrhosis	CYGB NFKB1 IL7R	1.45e-03	47	140	3	C0008312
Disease	venous thromboembolism	TSPAN15 CAAP1 ANK3 FASTKD2 PIEZO2 TC2N ABCB9 CYB5R3	1.64e-03	460	140	8	EFO_0004286
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH4	1.68e-03	13	140	2	DOID:397 (implicated_via_orthology)
Disease	Medulloblastoma	MYC MYCL KDM4C	1.74e-03	50	140	3	C0025149
Disease	Colorectal Neoplasms	MYC LGR5 TXNRD1 POSTN GUCY1A2 SESN2	2.13e-03	277	140	6	C0009404
Disease	factor XI measurement, coronary artery disease	TDRD15 NAA25 ZNF638 ANKS1A	2.23e-03	115	140	4	EFO_0001645, EFO_0004694
Disease	Yu-Zhi constitution type	GABRB2 PIEZO2	2.25e-03	15	140	2	EFO_0007638
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH4	2.25e-03	15	140	2	DOID:0050646 (implicated_via_orthology)
Disease	third ventricle volume measurement	ANK3 GUCY1A2	2.25e-03	15	140	2	EFO_0010335
Disease	phosphatidylcholine 38:6 measurement	AHCTF1 FASTKD2	2.57e-03	16	140	2	EFO_0010388
Disease	adverse effect, response to xenobiotic stimulus	CAAP1 ABCA2 TLCD4	2.80e-03	59	140	3	EFO_0009658, GO_0009410
Disease	Adenocarcinoma of lung (disorder)	MYC SRR ERP29 MAP3K15 ALOX12B	3.08e-03	206	140	5	C0152013
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	NSD2 HCK IL7R	3.08e-03	61	140	3	C1961102
Disease	Nuclear non-senile cataract	WFS1 EPHA2	3.25e-03	18	140	2	C1112705
Disease	Nuclear cataract	WFS1 EPHA2	3.25e-03	18	140	2	C0392557
Disease	Malignant Neoplasms	MYC BIRC6 MET EPHA2	3.29e-03	128	140	4	C0006826
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	TDRD15 NAA25 ANKS1A	3.37e-03	63	140	3	EFO_0001645, EFO_0004792
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNB	3.63e-03	19	140	2	DOID:2256 (is_implicated_in)
Disease	MYELODYSPLASTIC SYNDROME	MYC SAMD9 ATRX	4.01e-03	67	140	3	C3463824
Disease	Fetal Growth Retardation	SAMD9 NSD2	4.02e-03	20	140	2	C0015934
Disease	lymphocyte count	MYCL FLNB KIF1B CLSTN1 GRHL2 CERS5 GTF2IRD2B SPPL2A LPAR6 NFKB1 GTF2IRD2 ZNF638 SESN2 ATP2B4 IL7R	4.13e-03	1464	140	15	EFO_0004587
Disease	Benign Neoplasm	MYC BIRC6 EPHA2	4.18e-03	68	140	3	C0086692
Disease	Neoplasms	MYC BIRC6 EPHA2	4.18e-03	68	140	3	C0027651
Disease	congenital heart disease (implicated_via_orthology)	KMT2C UBE2R2 CDC34	4.36e-03	69	140	3	DOID:1682 (implicated_via_orthology)
Disease	lung non-small cell carcinoma (is_implicated_in)	NSD2 KMT2C NFKB1 IL7R	4.41e-03	139	140	4	DOID:3908 (is_implicated_in)
Disease	Neoplastic Cell Transformation	MYC NSD2 NFKB1 IL7R	4.41e-03	139	140	4	C0007621
Disease	Vertigo	SDK2 SPPL2A CADPS CWF19L1	4.41e-03	139	140	4	HP_0002321
Disease	periodontitis (biomarker_via_orthology)	POSTN MET	4.42e-03	21	140	2	DOID:824 (biomarker_via_orthology)
Disease	Bladder Neoplasm	MYC SMC1A KMT2C FERMT2	4.52e-03	140	140	4	C0005695
Disease	ascending aortic diameter	FLNB PIEZO2 HMCN1 HYDIN	4.52e-03	140	140	4	EFO_0021787
Disease	bipolar I disorder	TDRD15 ANK3 ANKS1B ATP2B4	4.64e-03	141	140	4	EFO_0009963
Disease	Malignant neoplasm of urinary bladder	MYC SMC1A KMT2C FERMT2	4.64e-03	141	140	4	C0005684
Disease	tissue plasminogen activator measurement, coronary artery disease	TDRD15 NAA25 ANKS1A	4.72e-03	71	140	3	EFO_0001645, EFO_0004791

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKIHVSPDFKTYVTV	APAF1	1221	O14727
KPLSVLKSLEEKYVA	BIRC6	4516	Q9NR09
ASKVKSLKPIDYVFE	CRYBG3	2736	Q68DQ2
DKKILFRYSVKVLTP	ADGB	1116	Q8N7X0
LDTVTFYKVIPKSKF	ERP29	41	P30040
KISHFKIPKYIVFVT	ACSF2	576	Q96CM8
YKLKLAKDITTIPTI	ARL14	31	Q8N4G2
KKIPTIILSITYKGV	ANKS1A	976	Q92625
VSLKPVSFYISDKKE	CAAP1	131	Q9H8G2
APVFKEKSYKATVIE	CLSTN1	161	O94985
LFEYFVVVSLKKKPS	DENND2B	696	P78524
ILEKVFISITKYPDK	CERS5	91	Q8N5B7
VKLVPSSSYIKVVKA	ATP2B4	1131	P23634
LIEISPYKFQKGKDV	ETNPPL	146	Q8TBG4
TLLKTKGVTDIKIYP	ATP7A	106	Q04656
KKPDFTTVKIVNYTV	IGDCC4	771	Q8TDY8
VLKPVISRVFEEKKY	RASAL1	366	O95294
KGIILVYDITKKETF	RAB12	116	Q6IQ22
VDLVIKVYFKDTHPK	CYB5R3	106	P00387
YPFKPKLTIKTAFVI	NPFFR2	251	Q9Y5X5
LDTDFVESLPVKVKY	NAP1L2	96	Q9ULW6
LPTIKDAYRKFEIKI	HSPG2	3676	P98160
SRFYSLKVAPKVKAT	UQCRC2	11	P22695
KLKTVLKYSPFVVSF	ITPKC	391	Q96DU7
FALESEIISKLYIPK	ANKRD36C	396	Q5JPF3
KVPTIILSVSYKGVK	ANKS1B	1101	Q7Z6G8
FTVKAASKYVDVPKP	CADPS	1211	Q9ULU8
VTYEEVVKLPAFKRK	CASK	726	O14936
PLVKSLLKSKFEEYV	KATNBL1	221	Q9H079
PYCVSIKITKVVLSK	KMT2C	986	Q8NEZ4
KAAKDSVKLVVRYTP	LIN7A	176	O14910
KADIAVPLVFTKYSE	MAP6	21	Q96JE9
IIKSVGELSVPEKYK	EDRF1	566	Q3B7T1
ITESFVDYIKTKPIV	KIF1B	1176	O60333
IVLYFKLRSKKTPAV	ATP5MK	41	Q96IX5
HVKYKTFEIPVIKIE	DDX58	876	O95786
YKTGIKKAPIQTYVL	CWF19L1	56	Q69YN2
SVYPEKLATKFVDKT	ECPAS	681	Q5VYK3
PFKVKVLPTYDASKV	FLNB	1506	O75369
AKYDLPATIDFIVKK	LIPF	146	P07098
KVEIIKHISAPEKTY	PCLO	3546	Q9Y6V0
TVKFLIPGKKYVANT	PCNX4	126	Q63HM2
IPTTIYKAKKIVSTI	KIAA1586	686	Q9HCI6
CFTKRQYPETKIIKT	NSD2	1056	O96028
PTAVIVFSYVKIIAK	OPN5	211	Q6U736
VLKKYGIPFDKITQE	KDM4C	251	Q9H3R0
VGLKKIIDFIYTAKL	KLHL9	101	Q9P2J3
FTYVAPSVLESVKEK	RPS6KB1	411	P23443
SIVDYKLITKKVVFS	GABRB2	211	P47870
IYFIETKKFLLIGKS	IL7R	91	P16871
IIKPAKYFSELEKSI	MSANTD3	6	Q96H12
LAIVYPFKSKTLRTK	LPAR6	116	P43657
LYFKIKPLLKSAETE	MYH1	836	P12882
YLSPKTVADTFEKVV	MIEF1	256	Q9NQG6
LKTVTFANDLKPKVY	IKBIP	271	Q70UQ0
YVAKVLKATLAEKFP	IQGAP3	1146	Q86VI3
IVPYSELVKKCKIDI	MACF1	2631	Q9UPN3
ELVKFLSVKYTTKQP	MAGEA13P	111	A6NCF6
KKFSLTVYVPPSIKD	HMCN1	3046	Q96RW7
TLVKLVYFEPKDITA	PANK2	221	Q9BZ23
KAVDIKKPLVSVYSN	MCAT	286	Q8IVS2
SQKEEKKIILTYFAP	FRMD5	261	Q7Z6J6
KVTKELYVKLTPVSL	ATRX	581	P46100
LSKAFKVKPFVVRDA	HYOU1	426	Q9Y4L1
KLVKLHAVVTKEPIY	HCK	316	P08631
LVKVVEESSPYFKVI	HYDIN	131	Q4G0P3
AIPLQKKSDITYFKT	GRHL2	456	Q6ISB3
DFYEEVKIKLPAKLT	DOCK8	626	Q8NF50
KISEAFVKIPVKLFA	DTX3L	356	Q8TDB6
VPVAIKTLKAGYTEK	EPHA2	641	P29317
EKKVLFYISPVNKLV	AVL9	201	Q8NBF6
KHKVEPVYFKILSGV	CYGB	116	Q8WWM9
AITDKDIVFYKTLKP	CYP4F8	116	P98187
LPLVVCVDKLTKVYK	ABCA2	986	Q9BZC7
VKSPSKKVLYREYVV	ANK3	2921	Q12955
RKLKTAPSYIKDVII	MDH1B	296	Q5I0G3
KIFPGKKSVVSEYVA	ALOX12B	241	O75342
KEKFTPKKIIAIANY	IFI16	621	Q16666
IPFKVDTILKYLKDH	IQUB	146	Q8NA54
IGPEDVINFKKIYKT	DDX24	691	Q9GZR7
LPPVKKNFYIESKAT	DDX53	171	Q86TM3
KTTKFTKKVQIDPYL	CPEB1	496	Q9BZB8
VYEGKIFTQKSKVPV	AHCTF1	1416	Q8WYP5
KKPLTKIVSYLLVAE	ESRRB	206	O95718
SIPELADYIKVFKPK	FERMT2	371	Q96AC1
TVLKTKYDKVGIPEF	GTF2IRD2	876	Q86UP8
TVLKTKYDKVGIPEF	GTF2IRD2B	876	Q6EKJ0
KVILALFTYVKKPEK	CFAP69	391	A5D8W1
ILIKDIPKEVSSYTF	SDK2	1871	Q58EX2
YLIVITKKIKVGEFF	SACM1L	71	Q9NTJ5
VVKDTLKKFLSFFPV	SACS	2951	Q9NZJ4
KLYVVQTVIKTAKFI	LRRC8D	306	Q7L1W4
KFETKAPFSSLKVII	LGR5	671	O75473
TLVKLVYFEPKDITA	PANK1	246	Q8TE04
EKKKTVDLLYSIFPG	GUCY1A2	486	P33402
KEPTIKFYTKQILEG	MAP3K15	746	Q6ZN16
YSLSQIKFSPVAKKL	MIGA1	61	Q8NAN2
IKFSPVAKKLFVVTA	MIGA1	66	Q8NAN2
KSDPYIVIKLGKTEI	FER1L6	1376	Q2WGJ9
YTLVITGKKITKIPL	MET	501	P08581
AIKIYKTSILVFKDR	RIOK1	206	Q9BRS2
LKVYIKTVACYPEKT	SESN2	421	P58004
YKPLTKSCEIKFLTF	MRPL39	116	Q9NYK5
TITKKYIKIPFQVSL	SENP7	541	Q9BQF6
KEVPFVVPKFKLSYI	TC2N	71	Q8N9U0
AIPSIYVKKLKQDFI	TDRD15	331	B5MCY1
TAIAKKYIRYEKPLV	SAMD9	816	Q5K651
PKVVILKKATAYILS	MYC	391	P01106
VTFLKTKIYSVEALP	FASTKD2	686	Q9NYY8
AIIDILTPYDTKKKA	PIP4K2B	366	P78356
VSLKKENIFTTPKYA	ST8SIA3	31	O43173
LYFKIKPLLKSAETE	MYH4	836	Q9Y623
AKTYIQTELPFKAKT	WIZ	1371	O95785
TVKALKPSVKVYAAE	SRR	196	Q9GZT4
LFSKPEVIKQKYETG	ESRP2	221	Q9H6T0
VFYLKLVKKETFRSP	SLC38A4	496	Q969I6
VVLDKLITIYKKPIS	RASGRF1	686	Q13972
KLLSYTKPDVAFLVA	ABCB9	176	Q9NP78
IPTKIIKYDILTKSS	BCO1	431	Q9HAY6
LKEYLTLKTFIAKVI	CLCN2	176	P51788
EVKKLFKSLCVPYFV	TXNRD1	81	Q16881
VKVPTTLAEYCVKTK	CDC34	181	P49427
KAPKVVILSKALEYL	MYCL	316	P12524
LKKTKTSEYPIIFVY	SPANXN3	41	Q5MJ09
YKFPKDVDSVIIKVV	SIDT1	191	Q9NXL6
SLTKIEKVFSKLLYP	USP35	306	Q9P2H5
KKEEYLTFSPLTVVI	SPPL2A	211	Q8TCT8
KYKTLESAFLAPAII	TSPAN15	51	O95858
AKAFTIKKTLEIYVP	PIEZO2	2156	Q9H5I5
VISKVLTFDLTKYPD	SMC1A	1211	Q14683
FEALKYPKFSKAIVI	TLCD4	161	Q96MV1
LEEPTVIKKYLLKVA	SNX5	256	Q9Y5X3
TKHKIPVKYLEFISE	MB	96	P02144
IVYKVQFDTKPLKFV	ZNFX1	426	Q9P2E3
LSSYELKKKPVVTIY	ZMYM6	171	O95789
AKSKTPYTIAETLVK	ZBED9	831	Q6R2W3
KVKFYIDVKKFPISI	SLC32A1	296	Q9H598
VKVPTTLAEYCIKTK	UBE2R2	181	Q712K3
KKYTKIIDGVPVEIT	POSTN	731	Q15063
KFQPTKVLGIYTFTK	UBR4	4846	Q5T4S7
STFHRIIPTKEKLYK	ZNF571	126	Q7Z3V5
YIETTPLTIKGKSVK	ZNF638	731	Q14966
CLSTYELKKKPIVTI	ZMYM4	421	Q5VZL5
TKKYAKGVIPSSLFL	WFS1	251	O76024
KSKNILFVITKPDVY	NACA	1961	E9PAV3
ELVTKLYEAAVKKVP	NAA25	96	Q14CX7
IVFKTPKYKDINITK	NFKB1	311	P19838