| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | cholesterol-protein transferase activity | 2.33e-08 | 3 | 58 | 3 | GO:0140853 | |
| GeneOntologyMolecularFunction | patched binding | 1.29e-06 | 8 | 58 | 3 | GO:0005113 | |
| GeneOntologyMolecularFunction | alkaline phosphatase activity | 1.23e-04 | 6 | 58 | 2 | GO:0004035 | |
| GeneOntologyMolecularFunction | zinc ion binding | 1.00e-03 | 891 | 58 | 9 | GO:0008270 | |
| GeneOntologyMolecularFunction | transition metal ion binding | 2.06e-03 | 1189 | 58 | 10 | GO:0046914 | |
| GeneOntologyMolecularFunction | peptidase activity | 2.76e-03 | 654 | 58 | 7 | GO:0008233 | |
| GeneOntologyBiologicalProcess | positive regulation of mRNA splicing, via spliceosome | 3.38e-11 | 44 | 58 | 7 | GO:0048026 | |
| GeneOntologyBiologicalProcess | positive regulation of mRNA processing | 7.49e-11 | 49 | 58 | 7 | GO:0050685 | |
| GeneOntologyBiologicalProcess | positive regulation of RNA splicing | 4.68e-10 | 63 | 58 | 7 | GO:0033120 | |
| GeneOntologyBiologicalProcess | regulation of mRNA processing | 1.37e-08 | 158 | 58 | 8 | GO:0050684 | |
| GeneOntologyBiologicalProcess | intein-mediated protein splicing | 2.11e-08 | 3 | 58 | 3 | GO:0016539 | |
| GeneOntologyBiologicalProcess | protein splicing | 2.11e-08 | 3 | 58 | 3 | GO:0030908 | |
| GeneOntologyBiologicalProcess | regulation of mRNA splicing, via spliceosome | 7.33e-08 | 129 | 58 | 7 | GO:0048024 | |
| GeneOntologyBiologicalProcess | regulation of RNA splicing | 1.12e-07 | 207 | 58 | 8 | GO:0043484 | |
| GeneOntologyBiologicalProcess | male sex differentiation | 1.39e-06 | 199 | 58 | 7 | GO:0046661 | |
| GeneOntologyBiologicalProcess | mRNA processing | RBMXL3 WDR33 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B SAFB2 RBMY1E PRMT7 | 2.81e-06 | 551 | 58 | 10 | GO:0006397 |
| GeneOntologyBiologicalProcess | regulation of mRNA metabolic process | RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B SAFB2 RBMY1E E2F1 | 3.76e-06 | 443 | 58 | 9 | GO:1903311 |
| GeneOntologyBiologicalProcess | mRNA splicing, via spliceosome | 6.85e-06 | 358 | 58 | 8 | GO:0000398 | |
| GeneOntologyBiologicalProcess | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 6.85e-06 | 358 | 58 | 8 | GO:0000377 | |
| GeneOntologyBiologicalProcess | RNA splicing, via transesterification reactions | 7.43e-06 | 362 | 58 | 8 | GO:0000375 | |
| GeneOntologyBiologicalProcess | positive regulation of smoothened signaling pathway | 7.69e-06 | 45 | 58 | 4 | GO:0045880 | |
| GeneOntologyBiologicalProcess | positive regulation of mRNA metabolic process | 7.90e-06 | 259 | 58 | 7 | GO:1903313 | |
| GeneOntologyBiologicalProcess | male gonad development | 8.42e-06 | 171 | 58 | 6 | GO:0008584 | |
| GeneOntologyBiologicalProcess | development of primary male sexual characteristics | 8.71e-06 | 172 | 58 | 6 | GO:0046546 | |
| GeneOntologyBiologicalProcess | self proteolysis | 9.37e-06 | 15 | 58 | 3 | GO:0097264 | |
| GeneOntologyBiologicalProcess | RNA splicing | RBMXL3 RBMY1A1 RBMY1C TADA2B RBMY1F RBMY1D RBMY1B RBMY1E PRMT7 | 1.03e-05 | 502 | 58 | 9 | GO:0008380 |
| GeneOntologyBiologicalProcess | cell fate specification | 2.47e-05 | 123 | 58 | 5 | GO:0001708 | |
| GeneOntologyBiologicalProcess | mRNA metabolic process | RBMXL3 WDR33 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B SAFB2 RBMY1E E2F1 PRMT7 | 4.23e-05 | 917 | 58 | 11 | GO:0016071 |
| GeneOntologyBiologicalProcess | sex differentiation | 5.65e-05 | 352 | 58 | 7 | GO:0007548 | |
| GeneOntologyBiologicalProcess | protein autoprocessing | 8.12e-05 | 30 | 58 | 3 | GO:0016540 | |
| GeneOntologyBiologicalProcess | reproductive structure development | 9.59e-05 | 383 | 58 | 7 | GO:0048608 | |
| GeneOntologyBiologicalProcess | reproductive system development | 1.04e-04 | 388 | 58 | 7 | GO:0061458 | |
| GeneOntologyBiologicalProcess | neuron fate commitment | 1.25e-04 | 91 | 58 | 4 | GO:0048663 | |
| GeneOntologyBiologicalProcess | developmental process involved in reproduction | CCNYL1 DHH WDR33 RBMY1A1 RBMY1D RBMY1B SAFB2 RBMY1E SHH IHH PRMT7 PGM3 | 1.38e-04 | 1235 | 58 | 12 | GO:0003006 |
| GeneOntologyBiologicalProcess | gonad development | 1.67e-04 | 292 | 58 | 6 | GO:0008406 | |
| GeneOntologyBiologicalProcess | development of primary sexual characteristics | 1.83e-04 | 297 | 58 | 6 | GO:0045137 | |
| GeneOntologyBiologicalProcess | spinal cord motor neuron differentiation | 2.08e-04 | 41 | 58 | 3 | GO:0021522 | |
| GeneOntologyBiologicalProcess | regulation of smoothened signaling pathway | 2.18e-04 | 105 | 58 | 4 | GO:0008589 | |
| GeneOntologyBiologicalProcess | hematopoietic progenitor cell differentiation | 2.30e-04 | 197 | 58 | 5 | GO:0002244 | |
| GeneOntologyBiologicalProcess | coenzyme A catabolic process | 2.76e-04 | 9 | 58 | 2 | GO:0015938 | |
| GeneOntologyBiologicalProcess | regulation of cerebellar granule cell precursor proliferation | 3.45e-04 | 10 | 58 | 2 | GO:0021936 | |
| GeneOntologyBiologicalProcess | central nervous system neuron differentiation | 3.58e-04 | 217 | 58 | 5 | GO:0021953 | |
| GeneOntologyBiologicalProcess | ventral spinal cord development | 5.54e-04 | 57 | 58 | 3 | GO:0021517 | |
| GeneOntologyBiologicalProcess | negative regulation of T cell differentiation in thymus | 5.94e-04 | 13 | 58 | 2 | GO:0033085 | |
| GeneOntologyBiologicalProcess | positive regulation of T cell differentiation in thymus | 5.94e-04 | 13 | 58 | 2 | GO:0033089 | |
| GeneOntologyBiologicalProcess | cell differentiation in spinal cord | 7.43e-04 | 63 | 58 | 3 | GO:0021515 | |
| GeneOntologyBiologicalProcess | regulation of neuroblast proliferation | 8.90e-04 | 67 | 58 | 3 | GO:1902692 | |
| GeneOntologyBiologicalProcess | thalamus development | 9.09e-04 | 16 | 58 | 2 | GO:0021794 | |
| GeneOntologyBiologicalProcess | cell proliferation in external granule layer | 9.09e-04 | 16 | 58 | 2 | GO:0021924 | |
| GeneOntologyBiologicalProcess | cerebellar granule cell precursor proliferation | 9.09e-04 | 16 | 58 | 2 | GO:0021930 | |
| GeneOntologyBiologicalProcess | regulation of immature T cell proliferation in thymus | 1.03e-03 | 17 | 58 | 2 | GO:0033084 | |
| GeneOntologyBiologicalProcess | regulation of immature T cell proliferation | 1.16e-03 | 18 | 58 | 2 | GO:0033083 | |
| GeneOntologyBiologicalProcess | cell proliferation in hindbrain | 1.16e-03 | 18 | 58 | 2 | GO:0021534 | |
| GeneOntologyBiologicalProcess | immature T cell proliferation in thymus | 1.29e-03 | 19 | 58 | 2 | GO:0033080 | |
| GeneOntologyBiologicalProcess | nucleoside bisphosphate catabolic process | 1.29e-03 | 19 | 58 | 2 | GO:0033869 | |
| GeneOntologyBiologicalProcess | ribonucleoside bisphosphate catabolic process | 1.29e-03 | 19 | 58 | 2 | GO:0034031 | |
| GeneOntologyBiologicalProcess | purine nucleoside bisphosphate catabolic process | 1.29e-03 | 19 | 58 | 2 | GO:0034034 | |
| GeneOntologyBiologicalProcess | immature T cell proliferation | 1.43e-03 | 20 | 58 | 2 | GO:0033079 | |
| GeneOntologyBiologicalProcess | smoothened signaling pathway | 1.52e-03 | 176 | 58 | 4 | GO:0007224 | |
| GeneOntologyBiologicalProcess | embryonic digestive tract morphogenesis | 1.58e-03 | 21 | 58 | 2 | GO:0048557 | |
| GeneOntologyCellularComponent | spliceosomal complex | 1.89e-06 | 215 | 57 | 7 | GO:0005681 | |
| GeneOntologyCellularComponent | male germ cell nucleus | 8.93e-05 | 86 | 57 | 4 | GO:0001673 | |
| GeneOntologyCellularComponent | germ cell nucleus | 2.56e-04 | 113 | 57 | 4 | GO:0043073 | |
| GeneOntologyCellularComponent | myofibril | 8.81e-04 | 273 | 57 | 5 | GO:0030016 | |
| GeneOntologyCellularComponent | contractile muscle fiber | 1.15e-03 | 290 | 57 | 5 | GO:0043292 | |
| GeneOntologyCellularComponent | extracellular matrix | 1.97e-03 | 656 | 57 | 7 | GO:0031012 | |
| GeneOntologyCellularComponent | external encapsulating structure | 2.00e-03 | 658 | 57 | 7 | GO:0030312 | |
| MousePheno | annular pancreas | 2.90e-05 | 3 | 44 | 2 | MP:0006261 | |
| MousePheno | thin interparietal bone | 2.90e-05 | 3 | 44 | 2 | MP:0030277 | |
| Domain | RBM1CTR | 1.35e-11 | 8 | 58 | 5 | PF08081 | |
| Domain | RBM1CTR | 1.35e-11 | 8 | 58 | 5 | IPR012604 | |
| Domain | Hedgehog_sig/DD-Pept_Zn-bd_dom | 2.84e-08 | 3 | 58 | 3 | IPR009045 | |
| Domain | Hedgehog_signalling_dom | 2.84e-08 | 3 | 58 | 3 | IPR000320 | |
| Domain | HintN | 2.84e-08 | 3 | 58 | 3 | SM00306 | |
| Domain | HintC | 2.84e-08 | 3 | 58 | 3 | SM00305 | |
| Domain | Hedgehog | 2.84e-08 | 3 | 58 | 3 | IPR001657 | |
| Domain | Hint_dom | 2.84e-08 | 3 | 58 | 3 | IPR001767 | |
| Domain | - | 2.84e-08 | 3 | 58 | 3 | 3.30.1380.10 | |
| Domain | Hint_dom_N | 2.84e-08 | 3 | 58 | 3 | IPR003587 | |
| Domain | Hint_dom_C | 2.84e-08 | 3 | 58 | 3 | IPR003586 | |
| Domain | HH_signal | 2.84e-08 | 3 | 58 | 3 | PF01085 | |
| Domain | Hint | 2.84e-08 | 3 | 58 | 3 | PF01079 | |
| Domain | - | 1.13e-07 | 4 | 58 | 3 | 2.170.16.10 | |
| Domain | Hedgehog/Intein_dom | 1.13e-07 | 4 | 58 | 3 | IPR028992 | |
| Domain | RRM_1 | 3.57e-06 | 208 | 58 | 7 | PF00076 | |
| Domain | RRM | 4.72e-06 | 217 | 58 | 7 | SM00360 | |
| Domain | RRM_dom | 6.34e-06 | 227 | 58 | 7 | IPR000504 | |
| Domain | RRM | 6.91e-06 | 230 | 58 | 7 | PS50102 | |
| Domain | INTEIN_N_TER | 9.48e-06 | 2 | 58 | 2 | PS50817 | |
| Domain | Intein_N | 9.48e-06 | 2 | 58 | 2 | IPR006141 | |
| Domain | Nucleotide-bd_a/b_plait | 1.46e-05 | 258 | 58 | 7 | IPR012677 | |
| Domain | Alk_phosphatase | 5.66e-05 | 4 | 58 | 2 | PF00245 | |
| Domain | Alkaline_phosphatase_AS | 5.66e-05 | 4 | 58 | 2 | IPR018299 | |
| Domain | Alkaline_phosphatase | 5.66e-05 | 4 | 58 | 2 | IPR001952 | |
| Domain | alkPPc | 5.66e-05 | 4 | 58 | 2 | SM00098 | |
| Domain | ALKALINE_PHOSPHATASE | 5.66e-05 | 4 | 58 | 2 | PS00123 | |
| Domain | - | 1.07e-04 | 244 | 58 | 6 | 3.30.70.330 | |
| Domain | Alkaline_phosphatase_core | 4.16e-03 | 31 | 58 | 2 | IPR017850 | |
| Domain | Alkaline_Pase-like_a/b/a | 4.16e-03 | 31 | 58 | 2 | IPR017849 | |
| Domain | - | 4.16e-03 | 31 | 58 | 2 | 3.40.720.10 | |
| Domain | TPR | 7.53e-03 | 129 | 58 | 3 | SM00028 | |
| Domain | Rossmann-like_a/b/a_fold | 7.89e-03 | 43 | 58 | 2 | IPR014729 | |
| Domain | - | 7.89e-03 | 43 | 58 | 2 | 3.40.50.620 | |
| Domain | TPR_repeat | 8.19e-03 | 133 | 58 | 3 | IPR019734 | |
| Pathway | KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION | 4.89e-07 | 6 | 42 | 3 | M47892 | |
| Pathway | REACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL | 8.54e-07 | 7 | 42 | 3 | MM15187 | |
| Pathway | REACTOME_LIGAND_RECEPTOR_INTERACTIONS | 8.54e-07 | 7 | 42 | 3 | MM15224 | |
| Pathway | REACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL | 1.36e-06 | 8 | 42 | 3 | M27444 | |
| Pathway | REACTOME_LIGAND_RECEPTOR_INTERACTIONS | 1.36e-06 | 8 | 42 | 3 | M27496 | |
| Pathway | KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR | 2.04e-06 | 9 | 42 | 3 | M47893 | |
| Pathway | KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 8.75e-06 | 14 | 42 | 3 | M47414 | |
| Pathway | REACTOME_ACTIVATION_OF_SMO | 8.75e-06 | 14 | 42 | 3 | MM15228 | |
| Pathway | WP_HEDGEHOG_SIGNALING_WP47 | 1.34e-05 | 16 | 42 | 3 | M39675 | |
| Pathway | REACTOME_ACTIVATION_OF_SMO | 1.95e-05 | 18 | 42 | 3 | M27500 | |
| Pathway | PID_HEDGEHOG_2PATHWAY | 3.64e-05 | 22 | 42 | 3 | M211 | |
| Pathway | WP_HEDGEHOG_SIGNALING_PATHWAY | 3.64e-05 | 22 | 42 | 3 | MM15924 | |
| Pathway | REACTOME_FORMATION_OF_LATERAL_PLATE_MESODERM | 8.62e-05 | 5 | 42 | 2 | M46432 | |
| Pathway | WP_HEDGEHOG_SIGNALING_WP4249 | 2.79e-04 | 43 | 42 | 3 | M39706 | |
| Pathway | KEGG_FOLATE_BIOSYNTHESIS | 4.69e-04 | 11 | 42 | 2 | M2220 | |
| Pathway | KEGG_HEDGEHOG_SIGNALING_PATHWAY | 6.11e-04 | 56 | 42 | 3 | M1053 | |
| Pathway | REACTOME_HEDGEHOG_LIGAND_BIOGENESIS | 8.23e-04 | 62 | 42 | 3 | MM15181 | |
| Pathway | REACTOME_HEDGEHOG_LIGAND_BIOGENESIS | 9.45e-04 | 65 | 42 | 3 | M27439 | |
| Pathway | REACTOME_DIGESTION | 1.76e-03 | 21 | 42 | 2 | MM15526 | |
| Pathway | REACTOME_HEDGEHOG_ON_STATE | 1.79e-03 | 81 | 42 | 3 | MM15225 | |
| Pathway | WP_MRNA_PROCESSING | 2.05e-03 | 451 | 42 | 6 | MM15946 | |
| Pathway | REACTOME_HEDGEHOG_ON_STATE | 2.12e-03 | 86 | 42 | 3 | M27497 | |
| Pubmed | 1.28e-16 | 7 | 59 | 6 | 8269511 | ||
| Pubmed | 1.68e-14 | 12 | 59 | 6 | 9598316 | ||
| Pubmed | 7.08e-14 | 6 | 59 | 5 | 15184870 | ||
| Pubmed | Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene. | 2.47e-13 | 7 | 59 | 5 | 8875892 | |
| Pubmed | An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells. | 3.73e-11 | 5 | 59 | 4 | 8817321 | |
| Pubmed | 3.73e-11 | 5 | 59 | 4 | 20016065 | ||
| Pubmed | The role of human and mouse Y chromosome genes in male infertility. | 3.73e-11 | 5 | 59 | 4 | 11097427 | |
| Pubmed | Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability. | 3.73e-11 | 5 | 59 | 4 | 19737860 | |
| Pubmed | 1.12e-10 | 6 | 59 | 4 | 18239052 | ||
| Pubmed | Identification of target messenger RNA substrates for mouse RBMY. | 1.12e-10 | 6 | 59 | 4 | 18492746 | |
| Pubmed | Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. | 1.12e-10 | 6 | 59 | 4 | 12356914 | |
| Pubmed | 1.12e-10 | 6 | 59 | 4 | 9499427 | ||
| Pubmed | 1.12e-10 | 6 | 59 | 4 | 15051956 | ||
| Pubmed | 2.60e-10 | 7 | 59 | 4 | 17001072 | ||
| Pubmed | The roles of RNA-binding proteins in spermatogenesis and male infertility. | 2.60e-10 | 7 | 59 | 4 | 10377282 | |
| Pubmed | 5.20e-10 | 8 | 59 | 4 | 7479793 | ||
| Pubmed | 1.56e-09 | 10 | 59 | 4 | 10601091 | ||
| Pubmed | 1.56e-09 | 10 | 59 | 4 | 9384609 | ||
| Pubmed | The role of Dby mRNA in early development of male mouse zygotes. | 3.66e-09 | 12 | 59 | 4 | 20543856 | |
| Pubmed | [Hedgehog signaling pathway and its impact on development of cancer therapy]. | 4.64e-09 | 3 | 59 | 3 | 18788453 | |
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 18063705 | ||
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 17392501 | ||
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 9009843 | ||
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 10579908 | ||
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 24342078 | ||
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 19074837 | ||
| Pubmed | 4.64e-09 | 3 | 59 | 3 | 8849902 | ||
| Pubmed | Comparative biological responses to human Sonic, Indian, and Desert hedgehog. | 4.64e-09 | 3 | 59 | 3 | 11472839 | |
| Pubmed | GASZ promotes germ cell derivation from embryonic stem cells. | 5.28e-09 | 13 | 59 | 4 | 23816659 | |
| Pubmed | 5.28e-09 | 13 | 59 | 4 | 10749975 | ||
| Pubmed | Absence of mDazl produces a final block on germ cell development at meiosis. | 7.38e-09 | 14 | 59 | 4 | 14611631 | |
| Pubmed | Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. | 1.01e-08 | 15 | 59 | 4 | 38234039 | |
| Pubmed | Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome. | 1.01e-08 | 15 | 59 | 4 | 14762062 | |
| Pubmed | Loss of maternal Trim28 causes male-predominant early embryonic lethality. | 1.75e-08 | 17 | 59 | 4 | 28115466 | |
| Pubmed | 1.85e-08 | 4 | 59 | 3 | 9053312 | ||
| Pubmed | 1.85e-08 | 4 | 59 | 3 | 7916661 | ||
| Pubmed | Sex differences in sex chromosome gene expression in mouse brain. | 2.24e-08 | 18 | 59 | 4 | 12023983 | |
| Pubmed | Developmental pathways in breast cancer and breast tumor-initiating cells: therapeutic implications. | 4.63e-08 | 5 | 59 | 3 | 22123293 | |
| Pubmed | 4.63e-08 | 5 | 59 | 3 | 19559697 | ||
| Pubmed | Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. | 4.63e-08 | 5 | 59 | 3 | 10050855 | |
| Pubmed | 4.63e-08 | 5 | 59 | 3 | 20519495 | ||
| Pubmed | Products, genetic linkage and limb patterning activity of a murine hedgehog gene. | 4.63e-08 | 5 | 59 | 3 | 7720571 | |
| Pubmed | Hedgehog and patched gene expression in adult ocular tissues. | 4.63e-08 | 5 | 59 | 3 | 9237688 | |
| Pubmed | 9.24e-08 | 6 | 59 | 3 | 20978073 | ||
| Pubmed | 9.24e-08 | 6 | 59 | 3 | 7589793 | ||
| Pubmed | 1.09e-07 | 26 | 59 | 4 | 35920200 | ||
| Pubmed | 1.62e-07 | 7 | 59 | 3 | 25639508 | ||
| Pubmed | Characterization of two patched receptors for the vertebrate hedgehog protein family. | 1.62e-07 | 7 | 59 | 3 | 9811851 | |
| Pubmed | Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. | 2.58e-07 | 8 | 59 | 3 | 10529434 | |
| Pubmed | 3.87e-07 | 9 | 59 | 3 | 25842978 | ||
| Pubmed | 3.87e-07 | 9 | 59 | 3 | 20570969 | ||
| Pubmed | Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4. | 3.87e-07 | 9 | 59 | 3 | 17881493 | |
| Pubmed | Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis. | 5.52e-07 | 10 | 59 | 3 | 21652647 | |
| Pubmed | 5.52e-07 | 10 | 59 | 3 | 11311154 | ||
| Pubmed | 7.58e-07 | 11 | 59 | 3 | 17028112 | ||
| Pubmed | 1.01e-06 | 12 | 59 | 3 | 18582859 | ||
| Pubmed | 1.01e-06 | 12 | 59 | 3 | 7590746 | ||
| Pubmed | A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. | 1.01e-06 | 12 | 59 | 3 | 27802136 | |
| Pubmed | Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. | 1.01e-06 | 12 | 59 | 3 | 10981962 | |
| Pubmed | Expression patterns of Hedgehog signalling pathway members during mouse palate development. | 1.31e-06 | 13 | 59 | 3 | 16168717 | |
| Pubmed | 1.31e-06 | 13 | 59 | 3 | 32332736 | ||
| Pubmed | 1.31e-06 | 13 | 59 | 3 | 22275805 | ||
| Pubmed | Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. | 1.31e-06 | 13 | 59 | 3 | 18632939 | |
| Pubmed | Cytoneme signaling provides essential contributions to mammalian tissue patterning. | 1.67e-06 | 14 | 59 | 3 | 38171360 | |
| Pubmed | Genetic interaction between Gli3 and Ezh2 during limb pattern formation. | 1.67e-06 | 14 | 59 | 3 | 29729398 | |
| Pubmed | 2.08e-06 | 15 | 59 | 3 | 25917826 | ||
| Pubmed | Lineage-specific biology revealed by a finished genome assembly of the mouse. | 2.39e-06 | 55 | 59 | 4 | 19468303 | |
| Pubmed | GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. | 2.56e-06 | 16 | 59 | 3 | 26932670 | |
| Pubmed | 2.56e-06 | 16 | 59 | 3 | 33328171 | ||
| Pubmed | Differentiation of insulin-producing cells from human neural progenitor cells. | 2.56e-06 | 16 | 59 | 3 | 15839736 | |
| Pubmed | Reproductive, Physiological, and Molecular Outcomes in Female Mice Deficient in Dhh and Ihh. | 2.83e-06 | 2 | 59 | 2 | 29788357 | |
| Pubmed | Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis. | 2.83e-06 | 2 | 59 | 2 | 32473614 | |
| Pubmed | Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond. | 2.83e-06 | 2 | 59 | 2 | 28574612 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 20854074 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 23468532 | ||
| Pubmed | Cholesterol modification of hedgehog signaling proteins in animal development. | 2.83e-06 | 2 | 59 | 2 | 8824192 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 15878962 | ||
| Pubmed | Hedgehog can drive terminal differentiation of amniote slow skeletal muscle. | 2.83e-06 | 2 | 59 | 2 | 15238161 | |
| Pubmed | New insight into hedgehog signaling in hematological malignancies. | 2.83e-06 | 2 | 59 | 2 | 24991722 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 26201092 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 21454803 | ||
| Pubmed | Differential requirements for shh in mammary tissue and hair follicle morphogenesis. | 2.83e-06 | 2 | 59 | 2 | 12217324 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 32223017 | ||
| Pubmed | Hedgehog signaling regulates expansion of pancreatic epithelial cells. | 2.83e-06 | 2 | 59 | 2 | 15766752 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 21945643 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 29088246 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 19856079 | ||
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 24344235 | ||
| Pubmed | IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice. | 2.83e-06 | 2 | 59 | 2 | 36853961 | |
| Pubmed | Usp7 promotes medulloblastoma cell survival and metastasis by activating Shh pathway. | 2.83e-06 | 2 | 59 | 2 | 28137592 | |
| Pubmed | Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice. | 2.83e-06 | 2 | 59 | 2 | 24135022 | |
| Pubmed | Myomegalin regulates Hedgehog pathway by controlling PDE4D at the centrosome. | 2.83e-06 | 2 | 59 | 2 | 34260267 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 19369449 | ||
| Pubmed | Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. | 2.83e-06 | 2 | 59 | 2 | 14520411 | |
| Pubmed | 2.83e-06 | 2 | 59 | 2 | 21981925 | ||
| Pubmed | Increased production of sonic hedgehog by ballooned hepatocytes. | 2.83e-06 | 2 | 59 | 2 | 21547909 | |
| Pubmed | Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice. | 3.10e-06 | 17 | 59 | 3 | 22402963 | |
| Pubmed | 3.10e-06 | 17 | 59 | 3 | 23955340 | ||
| Pubmed | 3.17e-06 | 59 | 59 | 4 | 11279525 | ||
| Pubmed | 3.72e-06 | 18 | 59 | 3 | 26869039 | ||
| Interaction | HHIP interactions | 1.28e-08 | 10 | 58 | 4 | int:HHIP | |
| Interaction | PTCH2 interactions | 2.49e-05 | 20 | 58 | 3 | int:PTCH2 | |
| Cytoband | Yq11.223 | 1.40e-07 | 93 | 59 | 5 | Yq11.223 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chrYq11 | 5.13e-05 | 311 | 59 | 5 | chrYq11 | |
| Cytoband | 3q24 | 7.37e-04 | 31 | 59 | 2 | 3q24 | |
| Cytoband | 22q12.1 | 7.86e-04 | 32 | 59 | 2 | 22q12.1 | |
| Cytoband | 2p13.1 | 8.87e-04 | 34 | 59 | 2 | 2p13.1 | |
| Cytoband | 4p16.1 | 4.69e-03 | 79 | 59 | 2 | 4p16.1 | |
| GeneFamily | RNA binding motif containing | 3.31e-08 | 213 | 43 | 8 | 725 | |
| GeneFamily | Alkaline phosphatases | 3.31e-05 | 4 | 43 | 2 | 1072 | |
| Coexpression | CHEN_ETV5_TARGETS_TESTIS | 8.42e-07 | 33 | 58 | 4 | MM701 | |
| Coexpression | ZHENG_IL22_SIGNALING_DN | 3.00e-06 | 45 | 58 | 4 | MM763 | |
| ToppCell | facs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.41e-06 | 193 | 56 | 5 | f92bbe70e6c725bfb8c08bfc2a94e375528151a3 | |
| ToppCell | facs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.41e-06 | 193 | 56 | 5 | 44ba79db566d0fa3bbcfe3adf9164bf8c3cb0bc3 | |
| Drug | hydantoin-5-propionic acid | 2.20e-07 | 21 | 58 | 4 | CID000000782 | |
| Drug | AZFd | 3.24e-07 | 23 | 58 | 4 | CID000196489 | |
| Drug | Vistar | 2.10e-06 | 36 | 58 | 4 | CID000040896 | |
| Drug | 2-chlorodideoxyadenosine | 4.34e-06 | 43 | 58 | 4 | CID000072194 | |
| Drug | bipy | 4.85e-06 | 97 | 58 | 5 | CID000001474 | |
| Drug | PKI166 | 6.78e-06 | 48 | 58 | 4 | CID006918403 | |
| Drug | 2-oyl | 7.15e-06 | 105 | 58 | 5 | CID000657137 | |
| Drug | HgCl | 7.37e-06 | 49 | 58 | 4 | CID000024182 | |
| Drug | Butylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A | 1.02e-05 | 195 | 58 | 6 | 4647_UP | |
| Drug | triparanol | 1.09e-05 | 54 | 58 | 4 | CID000006536 | |
| Drug | azafagomine | 1.35e-05 | 57 | 58 | 4 | CID011957435 | |
| Drug | thioglycolate | 2.58e-05 | 67 | 58 | 4 | CID000001133 | |
| Drug | AY9944 | 2.68e-05 | 23 | 58 | 3 | CID000009704 | |
| Drug | AC1LXO3B | 2.68e-05 | 23 | 58 | 3 | CID001356208 | |
| Drug | SU6668 | 3.07e-05 | 70 | 58 | 4 | CID000206042 | |
| Drug | p11-13 | 4.03e-05 | 75 | 58 | 4 | CID000015759 | |
| Drug | AC1NS51S | 4.91e-05 | 28 | 58 | 3 | CID005354165 | |
| Drug | 8-dehydrocholesterol | 4.91e-05 | 28 | 58 | 3 | CID000129846 | |
| Drug | Hi-5 | 8.88e-05 | 34 | 58 | 3 | CID005288553 | |
| Drug | AC1L1JOO | 9.69e-05 | 35 | 58 | 3 | CID000005137 | |
| Drug | Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A | 1.26e-04 | 191 | 58 | 5 | 3890_DN | |
| Drug | Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A | 1.39e-04 | 195 | 58 | 5 | 5388_DN | |
| Drug | Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; HL60; HT_HG-U133A | 1.39e-04 | 195 | 58 | 5 | 6146_DN | |
| Drug | Aminohippuric acid [61-78-9]; Down 200; 20.6uM; HL60; HT_HG-U133A | 1.42e-04 | 196 | 58 | 5 | 3076_DN | |
| Drug | Pralidoxime chloride [51-15-0]; Down 200; 23.2uM; HL60; HT_HG-U133A | 1.42e-04 | 196 | 58 | 5 | 3066_DN | |
| Drug | Hexetidine [141-94-6]; Down 200; 11.8uM; HL60; HT_HG-U133A | 1.46e-04 | 197 | 58 | 5 | 2457_DN | |
| Drug | Etofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A | 1.49e-04 | 198 | 58 | 5 | 5467_DN | |
| Drug | Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A | 1.49e-04 | 198 | 58 | 5 | 5639_UP | |
| Drug | felodipine; Down 200; 10uM; MCF7; HG-U133A | 1.53e-04 | 199 | 58 | 5 | 337_DN | |
| Drug | Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; HL60; HG-U133A | 1.56e-04 | 200 | 58 | 5 | 1788_UP | |
| Disease | primary bacterial infectious disease (implicated_via_orthology) | 4.56e-07 | 9 | 53 | 3 | DOID:0050338 (implicated_via_orthology) | |
| Disease | autism spectrum disorder (is_marker_for) | 6.61e-05 | 7 | 53 | 2 | DOID:0060041 (is_marker_for) | |
| Disease | Pain, Migratory | 9.51e-05 | 49 | 53 | 3 | C0751407 | |
| Disease | Suffering, Physical | 9.51e-05 | 49 | 53 | 3 | C0751408 | |
| Disease | Pain, Crushing | 9.51e-05 | 49 | 53 | 3 | C0458259 | |
| Disease | Pain, Splitting | 9.51e-05 | 49 | 53 | 3 | C0458257 | |
| Disease | Pain | 9.51e-05 | 49 | 53 | 3 | C0030193 | |
| Disease | Radiating pain | 9.51e-05 | 49 | 53 | 3 | C0234254 | |
| Disease | Pain, Burning | 9.51e-05 | 49 | 53 | 3 | C0234230 | |
| Disease | Ache | 9.51e-05 | 49 | 53 | 3 | C0234238 | |
| Disease | brain age measurement | 5.89e-04 | 20 | 53 | 2 | EFO_0010602 | |
| Disease | Edema | 1.00e-03 | 26 | 53 | 2 | C0013604 | |
| Disease | Anasarca | 1.00e-03 | 26 | 53 | 2 | C0151603 | |
| Disease | eye measurement | 1.08e-03 | 27 | 53 | 2 | EFO_0004731 | |
| Disease | attention deficit hyperactivity disorder, bipolar disorder | 1.42e-03 | 31 | 53 | 2 | EFO_0003888, MONDO_0004985 | |
| Disease | lateral ventricle volume measurement | 1.61e-03 | 33 | 53 | 2 | EFO_0008487 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| YHDADGHFHLIDGDK | 286 | O95394 | |
| LDGKEVIHLEAGGYH | 556 | Q96Q42 | |
| AELDFGEGEGHHLQH | 51 | Q8N7R7 | |
| LSALAHHYGLDRGVE | 31 | Q9HA90 | |
| DGYGEALGRDHSEHL | 371 | P0DJD3 | |
| DGYGEALGRDHSEHL | 371 | A6NDE4 | |
| DGYGEALGRDHSEHL | 371 | P0DJD4 | |
| DGYGEALGRDHSEHL | 371 | P0C7P1 | |
| DGYGEALGRDHSEHL | 371 | A6NEQ0 | |
| DGYGEALGRDHSEHL | 371 | Q15415 | |
| HGLGHFLGIDVHDVG | 366 | P12955 | |
| HRAYCGDGHRHEGVE | 401 | Q9Y215 | |
| LDELSRGLLHYAHDG | 1281 | Q86XX4 | |
| LGRAADDGGSHVHYA | 121 | Q9GZZ0 | |
| MEDRHGGCHGHYVHG | 331 | Q8N0V5 | |
| LRDYAGNLHESGVHG | 1046 | O75335 | |
| AHEVGHALGLGHSRY | 211 | Q99542 | |
| GLYRLHHSEAPELHG | 316 | Q8NB16 | |
| RLVGEIYGGHHSAFH | 146 | Q7RTU3 | |
| YLFVEGGRIDHGHHE | 326 | P09923 | |
| GGRIDHGHHEGVAYQ | 331 | P09923 | |
| FLFVEGGRIDHGHHE | 326 | P10696 | |
| GGRIDHGHHESRAYR | 331 | P10696 | |
| HDGQLYCGRHHAELL | 131 | Q2TBC4 | |
| ENAGGDLKDGHHHYE | 11 | P49915 | |
| HEALDYHFGLEEGEG | 406 | Q01094 | |
| IGEGALPSYEHAHRH | 151 | Q9NVM4 | |
| EDGHHAQDSLHYEGR | 131 | O43323 | |
| KYHVDHHRYLGGDGL | 126 | Q6QHC5 | |
| HYEAAAHGHDGVRLK | 71 | Q86UW8 | |
| DDLEHQGGHVLDHGH | 481 | P01042 | |
| ALASAHHGGEHFEGE | 11 | P15086 | |
| DGHHSEESLHYEGRA | 136 | Q14623 | |
| YAHLGLKGHRQEHGH | 126 | Q9UJV8 | |
| EPYGFHARGHSELHA | 66 | Q10571 | |
| RGACYGADHDLGRLH | 531 | Q6NUM9 | |
| SGGVAHFHCHLGYEL | 411 | Q9BYH1 | |
| DEGDEYFGHCHVLLG | 206 | Q96PX1 | |
| DGHHSEESLHYEGRA | 131 | Q15465 | |
| DIHGGGFDLRFPHHD | 361 | P49589 | |
| DVLYLGTEDGHLHRA | 451 | O95754 | |
| FSAGAEIGHHRRYHG | 36 | Q86TJ2 | |
| LQHRLGHGELAEHFY | 1201 | Q8TE82 | |
| RLVSEIYGGHHAGFH | 171 | Q13516 | |
| HILRHGHRGHDGEDD | 176 | P23327 | |
| DYGGLHHAAARISGD | 231 | O75570 | |
| GLDLHHRAHTGERPY | 386 | Q9UK11 | |
| VGGHYEENRGHSLDA | 506 | Q8N7X1 | |
| EGRPHGEHEYHLGRS | 91 | Q96PV0 | |
| HQLGELLAGHGRYAE | 31 | Q96HA7 | |
| LHGEYVGRACGHDHP | 706 | Q6U841 | |
| HHHYGGLFAGAEERS | 146 | Q9Y2X9 | |
| LTGIEDICGHYGHHH | 531 | P19634 | |
| MGDHRDGQHYGDDRH | 791 | Q14151 | |
| LGLHHHGEEAERAGY | 376 | Q9BWH6 | |
| HLLEGRKAGGGSYHH | 606 | Q2VWA4 | |
| YPEHGELLAHLGGAH | 3346 | Q96JG9 | |
| DGEHHDGYHRDEPFG | 1281 | Q9C0J8 | |
| HNYGGHDDDLSVRHC | 496 | Q93009 | |
| HHDYLLGHLDDEGKS | 76 | Q49AM3 | |
| HGRHVIGHIDDYSAL | 2176 | Q5VU43 |