Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription corepressor binding	PCLO HDAC2	1.13e-03	59	17	2	GO:0001222
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF426 ZNF217 HOXC9 HDAC2 TBX6	3.06e-03	1244	17	5	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF426 ZNF217 HOXC9 HDAC2 TBX6	3.37e-03	1271	17	5	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF426 ZNF217 HOXC9 HDAC2 TBX6	6.09e-03	1459	17	5	GO:0000977
GeneOntologyMolecularFunction	transcription coregulator binding	PCLO HDAC2	6.20e-03	140	17	2	GO:0001221
Pubmed	Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex.	ZNF217 HDAC2	3.37e-06	6	17	2	18625718
Pubmed	CoREST is an integral component of the CoREST- human histone deacetylase complex.	ZNF217 HDAC2	6.29e-06	8	17	2	11171972
Pubmed	Interaction of ZEB and histone deacetylase with the PLDLS-binding cleft region of monomeric C-terminal binding protein 2.	ZNF217 HDAC2	6.29e-06	8	17	2	19754958
Pubmed	Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex.	ZNF217 HDAC2	1.48e-05	12	17	2	17967884
Pubmed	An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation.	ZNF217 HDAC2	1.75e-05	13	17	2	16079794
Pubmed	Coordinated histone modifications mediated by a CtBP co-repressor complex.	ZNF217 HDAC2	2.35e-05	15	17	2	12700765
Pubmed	A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.	ZNF217 HDAC2	3.42e-05	18	17	2	12493763
Pubmed	RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer.	ZNF217 HDAC2	6.70e-05	25	17	2	31636387
Pubmed	PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.	ZNF217 HDAC2	1.04e-04	31	17	2	29846670
Pubmed	ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.	ZNF217 HDAC2	1.18e-04	33	17	2	36414381
Pubmed	PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.	PCLO HDAC2	1.82e-04	41	17	2	22325352
Pubmed	Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.	B3GNT4 QRICH2	4.88e-04	67	17	2	23263486
Disease	Mental Depression	PCLO HDAC2	8.18e-03	254	16	2	C0011570
Disease	hematocrit	BCLAF3 SRSF4 TBX6	1.61e-02	1011	16	3	EFO_0004348
Disease	mean platelet volume	BCLAF3 ZNF217 TBX6	1.65e-02	1020	16	3	EFO_0004584
Disease	S-6-hydroxywarfarin measurement	PCLO MINK1	1.66e-02	368	16	2	EFO_0803326

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGRHPYLGKYKAGFM	AOX1	846	Q06278
DSMYPGYRGPGYLSA	QRICH2	941	Q9H0J4
RSYPDYMYGSPGELR	HOXC9	136	P31274
YDRSGPYGYRGIGGM	PCLO	2976	Q9Y6V0
YMYKPHRGYSPGRGD	BCLAF3	91	A2AJT9
MYRATHYPPYAGGGG	B3GNT4	266	Q9C0J1
HYPPYAGGGGYVMSR	B3GNT4	271	Q9C0J1
GPHSHRLYYLGMPYG	DPP9	66	Q86TI2
HGFGGRPPYYSEEMF	ENAM	206	Q9NRM1
GNYYYGQGHPMKPHR	HDAC2	21	Q92769
YDKGVKGGTYPRRYH	MAP3K3	266	Q99759
RKPLYHYGRGMNPAD	MINK1	501	Q8N4C8
YGYRRSGRDKYGPPT	SRSF4	86	Q08170
YEYYPHVYPGRRGSM	TRAPPC12	461	Q8WVT3
PEMTPYEGGYYHGKL	UBE2J2	51	Q8N2K1
MYHPRELYPSLGAGY	TBX6	1	O95947
YRRGYDLPKYHMVRG	ZNF217	936	O75362
GKGYRYPAYLSIHMR	ZNF426	286	Q9BUY5