Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein domain specific binding

NCOA2 NCOA3 PDCD6IP ATXN2 TJP1 LITAF PLSCR1 HGS TRPS1

8.53e-06875339GO:0019904
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA2 NCOA3 ARID1B ARID1A SS18 GPS2

9.11e-06303336GO:0003713
GeneOntologyMolecularFunctionprotein-lysine 6-oxidase activity

LOXL1 LOXL2

2.64e-055332GO:0004720
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA2 NCOA3 SS18

1.39e-0461333GO:0030374
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA2 NCOA3 ARID1B ARID1A SS18 GPS2

2.81e-04562336GO:0003712
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

LOXL1 LOXL2

3.13e-0416332GO:0016641
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

LOXL1 LOXL2

4.94e-0420332GO:0016638
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA2 NCOA3 ARID1B ARID1A SS18 TAB3 HGS GPS2

1.33e-031356338GO:0060090
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

NCOA2 NCOA3

1.44e-0334332GO:0046966
GeneOntologyMolecularFunctionepidermal growth factor receptor binding

ATXN2 PLSCR1

2.09e-0341332GO:0005154
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA2 NCOA3 ARID1B ARID1A SS18 HGS GPS2

2.47e-031160337GO:0030674
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA2 NCOA3

3.46e-0353332GO:0030331
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA2 NCOA3 ARID1A

3.59e-03187333GO:0016922
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

NCOA3 ARID1A SS18 LOXL2

7.12e-0678334GO:2000036
GeneOntologyBiologicalProcesspeptidyl-lysine oxidation

LOXL1 LOXL2

2.47e-055332GO:0018057
GeneOntologyBiologicalProcesspositive regulation of stem cell population maintenance

NCOA3 ARID1A SS18

7.37e-0551333GO:1902459
GeneOntologyBiologicalProcessprotein oxidation

LOXL1 LOXL2

2.23e-0414332GO:0018158
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOA2 NCOA3 ARID1A GPS2

2.92e-04202334GO:0141193
GeneOntologyBiologicalProcesspositive regulation of exosomal secretion

PDCD6IP HGS

2.94e-0416332GO:1903543
GeneOntologyBiologicalProcessnuclear receptor-mediated glucocorticoid signaling pathway

NCOA2 ARID1A

3.33e-0417332GO:0042921
GeneOntologyBiologicalProcesspositive regulation of intracellular steroid hormone receptor signaling pathway

NCOA2 NCOA3

3.74e-0418332GO:0033145
GeneOntologyBiologicalProcessnuclear receptor-mediated corticosteroid signaling pathway

NCOA2 ARID1A

3.74e-0418332GO:0031958
GeneOntologyBiologicalProcessregulation of exosomal secretion

PDCD6IP HGS

4.63e-0420332GO:1903541
GeneOntologyBiologicalProcessstem cell population maintenance

NCOA3 ARID1A SS18 LOXL2

5.35e-04237334GO:0019827
GeneOntologyBiologicalProcessnegative regulation of developmental process

FOXJ2 NCOA3 ATXN2 SS18 LOXL2 HGS GPS2 STATH

5.38e-041220338GO:0051093
GeneOntologyBiologicalProcessblood vessel development

FOXJ2 AMOTL2 ARID1A TJP1 LOXL1 LOXL2 HGS

5.62e-04929337GO:0001568
GeneOntologyBiologicalProcessmaintenance of cell number

NCOA3 ARID1A SS18 LOXL2

5.79e-04242334GO:0098727
GeneOntologyBiologicalProcessresponse to mitochondrial depolarisation

VPS13C GPS2

6.15e-0423332GO:0098780
GeneOntologyBiologicalProcessvesicle localization

BSN PDCD6IP TFG HGS

6.25e-04247334GO:0051648
GeneOntologyBiologicalProcessexosomal secretion

PDCD6IP HGS

6.70e-0424332GO:1990182
GeneOntologyBiologicalProcessvasculature development

FOXJ2 AMOTL2 ARID1A TJP1 LOXL1 LOXL2 HGS

7.22e-04969337GO:0001944
GeneOntologyBiologicalProcessextracellular exosome biogenesis

PDCD6IP HGS

7.28e-0425332GO:0097734
GeneOntologyBiologicalProcessextracellular vesicle biogenesis

PDCD6IP HGS

8.50e-0427332GO:0140112
GeneOntologyBiologicalProcessperoxisome proliferator activated receptor signaling pathway

NCOA2 GPS2

9.14e-0428332GO:0035357
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

ARID1B ARID1A

9.81e-0429332GO:2000819
GeneOntologyCellularComponentnpBAF complex

ARID1B ARID1A SS18

1.17e-0614323GO:0071564
GeneOntologyCellularComponentSWI/SNF complex

ARID1B ARID1A SS18

1.29e-0530323GO:0016514
GeneOntologyCellularComponentendoplasmic reticulum exit site

SEC31A PDCD6IP TFG

3.59e-0542323GO:0070971
GeneOntologyCellularComponentbBAF complex

ARID1B ARID1A

1.01e-0410322GO:0140092
GeneOntologyCellularComponentbrahma complex

ARID1B ARID1A

2.04e-0414322GO:0035060
GeneOntologyCellularComponentnBAF complex

ARID1B ARID1A

2.69e-0416322GO:0071565
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

ARID1B ARID1A SS18

4.23e-0496323GO:0070603
GeneOntologyCellularComponentcytoplasmic stress granule

ATXN2L CASC3 ATXN2

4.23e-0496323GO:0010494
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

ATXN2L CASC3 SNRPB2 ATXN2

7.26e-04269324GO:0036464
GeneOntologyCellularComponentnuclear protein-containing complex

NCOA2 CASC3 NCOA3 ARID1B ARID1A SNRPB2 SS18 DROSHA

8.79e-041377328GO:0140513
GeneOntologyCellularComponentribonucleoprotein granule

ATXN2L CASC3 SNRPB2 ATXN2

9.24e-04287324GO:0035770
GeneOntologyCellularComponentATPase complex

ARID1B ARID1A SS18

9.99e-04129323GO:1904949
GeneOntologyCellularComponentbicellular tight junction

AMOTL2 PDCD6IP TJP1

1.04e-03131323GO:0005923
GeneOntologyCellularComponenttight junction

AMOTL2 PDCD6IP TJP1

1.24e-03139323GO:0070160
GeneOntologyCellularComponentchromatin

FOXJ2 NCOA2 NCOA3 ARID1B ARID1A SS18 LOXL2 TRPS1

1.40e-031480328GO:0000785
GeneOntologyCellularComponentendosome

SEC31A AMOTL2 PDCD6IP LITAF VPS13C TAB3 HGS

1.63e-031167327GO:0005768
GeneOntologyCellularComponentapical junction complex

AMOTL2 PDCD6IP TJP1

1.79e-03158323GO:0043296
GeneOntologyCellularComponentlate endosome membrane

LITAF VPS13C HGS

2.55e-03179323GO:0031902
DomainLsmAD

ATXN2L ATXN2

3.03e-062332PF06741
DomainBAF250_C

ARID1B ARID1A

3.03e-062332IPR033388
DomainBAF250_C

ARID1B ARID1A

3.03e-062332PF12031
DomainLsmAD_domain

ATXN2L ATXN2

3.03e-062332IPR009604
DomainSM_dom_ATX

ATXN2L ATXN2

3.03e-062332IPR025852
DomainSM-ATX

ATXN2L ATXN2

3.03e-062332PF14438
DomainDUF4927

NCOA2 NCOA3

3.03e-062332PF16279
DomainLsmAD

ATXN2L ATXN2

3.03e-062332SM01272
DomainBAF250/Osa

ARID1B ARID1A

3.03e-062332IPR021906
DomainDUF4927

NCOA2 NCOA3

3.03e-062332IPR032565
DomainDUF1518

NCOA2 NCOA3

9.07e-063332PF07469
DomainDUF1518

NCOA2 NCOA3

9.07e-063332IPR010011
DomainSrc1_rcpt_coact

NCOA2 NCOA3

9.07e-063332IPR008955
DomainNuclear_rcpt_coactivator

NCOA2 NCOA3

9.07e-063332IPR017426
DomainDUF1518

NCOA2 NCOA3

9.07e-063332SM01151
DomainNuc_rcpt_coact_Ncoa-typ

NCOA2 NCOA3

9.07e-063332IPR014920
DomainSRC-1

NCOA2 NCOA3

9.07e-063332IPR014935
DomainSRC-1

NCOA2 NCOA3

9.07e-063332PF08832
Domain-

NCOA2 NCOA3

9.07e-0633324.10.630.10
DomainNuc_rec_co-act

NCOA2 NCOA3

9.07e-063332PF08815
DomainLysyl_oxidase

LOXL1 LOXL2

3.02e-055332IPR001695
DomainLysyl_oxidase_CS

LOXL1 LOXL2

3.02e-055332IPR019828
DomainLYSYL_OXIDASE

LOXL1 LOXL2

3.02e-055332PS00926
DomainLysyl_oxidase

LOXL1 LOXL2

3.02e-055332PF01186
DomainNuc_rcpt_coact

NCOA2 NCOA3

4.52e-056332IPR009110
DomainPAM2

ATXN2L ATXN2

1.08e-049332PF07145
DomainAtaxin-2_C

ATXN2L ATXN2

1.08e-049332IPR009818
Domain-

ARID1B ARID1A

3.13e-04153321.10.150.60
DomainARID

ARID1B ARID1A

3.13e-0415332PF01388
DomainBRIGHT

ARID1B ARID1A

3.13e-0415332SM00501
DomainARID_dom

ARID1B ARID1A

3.13e-0415332IPR001606
DomainARID

ARID1B ARID1A

3.13e-0415332PS51011
DomainPAS

NCOA2 NCOA3

8.85e-0425332PF00989
DomainPAS_fold

NCOA2 NCOA3

8.85e-0425332IPR013767
DomainPAS

NCOA2 NCOA3

1.45e-0332332SM00091
DomainPAS

NCOA2 NCOA3

1.64e-0334332IPR000014
DomainPAS

NCOA2 NCOA3

1.64e-0334332PS50112
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

ARID1B ARID1A SS18

5.40e-0542253M48237
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA2 NCOA3

1.64e-0411252M47503
PathwayWP_EGFEGFR_SIGNALING

NCOA3 ATXN2 PLSCR1 HGS

1.76e-04162254M39334
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA2 NCOA3

3.13e-0415252M119
PathwayWP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING

LOXL1 LOXL2

4.04e-0417252M39686
PathwayWP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS

PDCD6IP HGS

4.54e-0418252M39737
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

LOXL1 LOXL2

4.54e-0418252M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

LOXL1 LOXL2

4.54e-0418252MM14882
PathwayREACTOME_SIGNALING_BY_HIPPO

AMOTL2 TJP1

5.63e-0420252MM14813
PathwayREACTOME_SIGNALING_BY_HIPPO

AMOTL2 TJP1

5.63e-0420252M591
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

ARID1B ARID1A SS18

6.12e-0495253M48268
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

ARID1B ARID1A SS18

6.51e-0497253M48262
PathwayBIOCARTA_VDR_PATHWAY

NCOA3 ARID1A

6.82e-0422252MM1370
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA2 NCOA3 GPS2

1.15e-03118253M27316
PathwayWP_KLEEFSTRA_SYNDROME

ARID1B ARID1A

1.19e-0329252M48076
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

NCOA2 ARID1B ARID1A GPS2

1.25e-03272254M29619
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA2 NCOA3

1.27e-0330252M207
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

ARID1B ARID1A

1.36e-0331252M39522
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

NCOA2 NCOA3

1.45e-0332252M39567
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

ARID1B ARID1A

1.73e-0335252M47969
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

ARID1B ARID1A SS18

1.77e-03137253M48232
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1B ARID1A

1.94e-0337252M27797
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

ARID1B ARID1A SS18

1.96e-03142253M48257
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LOXL1 LOXL2

2.15e-0339252MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LOXL1 LOXL2

2.73e-0344252M26969
Pubmed

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor.

ARID1B SEC31A PDCD6IP ARID1A TFG

1.15e-095033527716508
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 NCOA3 ARID1B ARID1A ZC3H4 GPS2 TRPS1

5.37e-0926833733640491
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA2 ATXN2L NCOA3 R3HDM2 TAB3 GPS2

6.34e-0915233638360978
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

NCOA2 ATXN2L CASC3 ARID1B TSC22D2 AMOTL2 PDCD6IP TFG ATXN2 ZC3H4

8.70e-09922331027609421
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA2 NCOA3 ARID1B ARID1A TRPS1

1.54e-088333528794006
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

CASC3 AMOTL2 ARID1A SS18 ZC3H4 LOXL2 TRPS1

2.34e-0833233737433992
Pubmed

Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.

PDCD6IP TFG ATXN2 HGS

2.37e-083233419542561
Pubmed

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.

ARID1B ARID1A SS18

2.72e-08733323540691
Pubmed

Human transcription factor protein interaction networks.

NCOA2 NCOA3 R3HDM2 ARID1B ARID1A ATXN2 SS18 TAB3 HGS GPS2 TRPS1

4.56e-081429331135140242
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

ATXN2L ARID1B AMOTL2 ARID1A SNRPB2 ATXN2 TJP1 DROSHA

8.59e-0861533831048545
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA2 NCOA3 ARID1B BSN PDCD6IP ARID1A SS18 TRPS1

1.14e-0763833831182584
Pubmed

Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion.

SEC31A PDCD6IP HGS

1.28e-071133329604273
Pubmed

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

ARID1B ARID1A SS18

1.70e-071233311734557
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA2 CASC3 NCOA3 SEC31A BSN PDCD6IP ATXN2 TJP1 ZC3H4

1.96e-0796333928671696
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

ARID1B SEC31A PDCD6IP ARID1A TFG ZC3H4 HGS

2.55e-0747233738943005
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

ARID1B ARID1A SS18

3.51e-071533323785148
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 ATXN2L ARID1B AMOTL2 ARID1A TJP1 TAB3

7.04e-0754933738280479
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 CASC3 PDCD6IP ARID1A ATXN2 TJP1 NDUFB8 VPS13C LOXL2 TRPS1

7.54e-071489331028611215
Pubmed

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.

ARID1B ARID1A

8.73e-07233237611161
Pubmed

Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.

ARID1B ARID1A

8.73e-07233232791957
Pubmed

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.

ARID1B ARID1A

8.73e-07233234386776
Pubmed

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.

ARID1B ARID1A

8.73e-07233229890703
Pubmed

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

ARID1B ARID1A

8.73e-07233223202128
Pubmed

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

NCOA2 NCOA3

8.73e-07233230048685
Pubmed

ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.

ARID1B ARID1A

8.73e-07233233890484
Pubmed

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

ARID1B ARID1A

8.73e-07233224788099
Pubmed

Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis.

NCOA2 NCOA3

8.73e-07233221220509
Pubmed

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

ARID1B ARID1A

8.73e-07233228967863
Pubmed

Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Distinct Entity Characterized by Recurrent NCOA2/3 Gene Fusions.

NCOA2 NCOA3

8.73e-07233230273195
Pubmed

Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.

ARID1B ARID1A

8.73e-07233233052929
Pubmed

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

ARID1B ARID1A

8.73e-07233224562383
Pubmed

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.

ATXN2L ATXN2

8.73e-0723328896555
Pubmed

Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis.

LOXL1 LOXL2

8.73e-07233229125826
Pubmed

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

ARID1B ARID1A

8.73e-07233227562491
Pubmed

Effects of a Levonorgestrel-Releasing Intrauterine System on the Expression of Steroid Receptor Coregulators in Adenomyosis.

NCOA2 NCOA3

8.73e-07233226040939
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

8.91e-0735133638297188
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOA2 NCOA3 ARID1B ARID1A

9.12e-077833428611094
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

ARID1B ARID1A SS18

1.36e-062333330962207
Pubmed

A protein interaction landscape of breast cancer.

ARID1B SEC31A AMOTL2 ARID1A SS18 LOXL2 HGS

1.83e-0663433734591612
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOA2 NCOA3 ARID1B PDCD6IP ARID1A TRPS1

1.84e-0639833635016035
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

ARID1B ARID1A SS18

2.24e-062733329374058
Pubmed

Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.

ARID1B ARID1A TFG

2.51e-062833330037996
Pubmed

Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.

ARID1B ARID1A

2.62e-06333233432679
Pubmed

The copper dependent-lysyl oxidases contribute to the pathogenesis of pulmonary emphysema in chronic obstructive pulmonary disease patients.

LOXL1 LOXL2

2.62e-06333228965583
Pubmed

The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.

NCOA2 NCOA3

2.62e-06333221035760
Pubmed

Ataxin-2-like is a regulator of stress granules and processing bodies.

ATXN2L ATXN2

2.62e-06333223209657
Pubmed

Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.

NCOA2 NCOA3

2.62e-06333218845648
Pubmed

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.

ARID1B ARID1A

2.62e-06333221647563
Pubmed

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

NCOA2 NCOA3

2.62e-06333212138202
Pubmed

Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.

NCOA2 NCOA3

2.62e-06333221059860
Pubmed

Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.

ARID1B ARID1A

2.62e-06333222426308
Pubmed

The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms.

LOXL1 LOXL2

2.62e-06333223494965
Pubmed

Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.

ARID1B ARID1A

2.62e-06333224382590
Pubmed

Prognostic value of novel biomarkers in astrocytic brain tumors: nuclear receptor co-regulators AIB1, TIF2, and PELP1 are associated with high tumor grade and worse patient prognosis.

NCOA2 NCOA3

2.62e-06333221735116
Pubmed

Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.

NCOA2 NCOA3

2.62e-06333216675958
Pubmed

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

ARID1B ARID1A

2.62e-06333234044070
Pubmed

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.

ARID1B ARID1A

2.62e-06333226716708
Pubmed

The nuclear receptor coactivators p300/CBP/cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1.

NCOA2 NCOA3

2.62e-06333211923473
Pubmed

FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.

NCOA2 NCOA3

2.62e-06333215698540
Pubmed

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene.

NCOA2 NCOA3

2.62e-0633329506940
Pubmed

Structure and chromosomal locations of mouse steroid receptor coactivator gene family.

NCOA2 NCOA3

2.62e-06333210501088
Pubmed

Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers.

NCOA2 NCOA3

2.62e-06333228390937
Pubmed

ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner.

SEC31A PDCD6IP

2.62e-06333217196169
Pubmed

Estrogen signaling in colorectal carcinoma microenvironment: expression of ERbeta1, AIB-1, and TIF-2 is upregulated in cancer-associated myofibroblasts and correlates with disease progression.

NCOA2 NCOA3

2.62e-06333219277704
Pubmed

Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.

NCOA2 NCOA3

2.62e-06333223927929
Pubmed

Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

NCOA2 NCOA3

2.62e-06333219052561
Pubmed

Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.

SEC31A PDCD6IP

2.62e-06333225667979
Pubmed

The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.

NCOA2 NCOA3

2.62e-06333216423883
Pubmed

ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.

ARID1B ARID1A

2.62e-06333234512623
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

ATXN2L ARID1B ARID1A

2.80e-062933336800290
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

R3HDM2 ARID1B AMOTL2 ARID1A TJP1 HGS

3.55e-0644633624255178
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOA2 NCOA3 ARID1B ARID1A TFG ATXN2

4.08e-0645733632344865
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

CASC3 NCOA3 SEC31A AMOTL2 SNRPB2 TJP1 DROSHA GPS2

4.38e-06103833826673895
Pubmed

Global proteomics of Ubqln2-based murine models of ALS.

PDCD6IP TFG SS18 TAB3 HGS

4.58e-0626133533277362
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ARID1A ATXN2 TJP1 TAB3 HGS

4.75e-0626333534702444
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ATXN2L CASC3 ARID1B TFG TJP1 VPS13C HGS

4.76e-0673333734672954
Pubmed

miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.

NCOA2 NCOA3

5.23e-06433226066330
Pubmed

Differential expression of the LOX family genes in human colorectal adenocarcinomas.

LOXL1 LOXL2

5.23e-06433219724858
Pubmed

Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia.

TJP1 DROSHA

5.23e-06433229339534
Pubmed

Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.

NCOA2 NCOA3

5.23e-06433212893883
Pubmed

Lysyl oxidases: a novel multifunctional amine oxidase family.

LOXL1 LOXL2

5.23e-06433211642359
Pubmed

Estrogen receptor alpha/beta, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?

NCOA2 NCOA3

5.23e-06433219198856
Pubmed

Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.

NCOA2 NCOA3

5.23e-06433222560224
Pubmed

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.

ATXN2L ATXN2

5.23e-06433217392519
Pubmed

Undifferentiated Endometrial Carcinomas Show Frequent Loss of Core Switch/Sucrose Nonfermentable Complex Proteins.

ARID1B ARID1A

5.23e-06433228863077
Pubmed

P160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain.

NCOA2 NCOA3

5.23e-06433218267973
Pubmed

Selective recruitment of p160 coactivators on glucocorticoid-regulated promoters in Schwann cells.

NCOA2 NCOA3

5.23e-06433215331759
Pubmed

Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2.

NCOA2 NCOA3

5.23e-06433210598588
Pubmed

Structural and functional diversity of lysyl oxidase and the LOX-like proteins.

LOXL1 LOXL2

5.23e-06433212686136
Pubmed

Interactions of RXR with coactivators are differentially mediated by helix 11 of the receptor's ligand binding domain.

NCOA2 NCOA3

5.23e-06433211851396
Pubmed

Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.

NCOA2 NCOA3

5.23e-06433226267537
Pubmed

Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

ARID1B ARID1A

5.23e-06433215170388
Pubmed

Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.

ARID1B ARID1A

5.23e-06433211988099
Pubmed

Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells.

NCOA2 NCOA3

5.23e-06433219462000
Pubmed

Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.

NCOA2 NCOA3

5.23e-06433219095746
Pubmed

Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function.

PDCD6IP HGS

5.23e-06433217014699
Pubmed

The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.

NCOA2 NCOA3

5.23e-06433215563469
Pubmed

Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.

NCOA2 NCOA3

5.23e-06433215563453
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ARID1B SEC31A PDCD6IP ARID1A SNRPB2 TJP1 ZC3H4 DROSHA

5.94e-06108233838697112
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA2 ATXN2L NCOA3 ARID1B ARID1A SNRPB2 ATXN2 GPS2

6.84e-06110333834189442
InteractionSOX17 interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 GPS2 TRPS1

1.60e-1095337int:SOX17
InteractionTBXT interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 GPS2 TRPS1

6.58e-10116337int:TBXT
InteractionFAM168A interactions

R3HDM2 ARID1B AMOTL2 TFG TJP1 PLSCR1 HGS

2.72e-09142337int:FAM168A
InteractionWWP2 interactions

ATXN2L ARID1B AMOTL2 PDCD6IP ARID1A SNRPB2 ATXN2 TJP1 LITAF DROSHA TAB3 HGS

4.02e-098403312int:WWP2
InteractionSOX10 interactions

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

7.69e-0992336int:SOX10
InteractionPAX8 interactions

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

2.39e-08111336int:PAX8
InteractionSMG7 interactions

NCOA2 NCOA3 R3HDM2 ARID1B ARID1A ATXN2 ZC3H4 TRPS1

3.55e-08319338int:SMG7
InteractionPAX7 interactions

NCOA3 ARID1B ARID1A SS18 GPS2 TRPS1

4.64e-08124336int:PAX7
InteractionPAX9 interactions

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

6.16e-08130336int:PAX9
InteractionETV4 interactions

NCOA2 NCOA3 ARID1B ARID1A SS18

8.94e-0869335int:ETV4
InteractionSOX15 interactions

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

9.99e-08141336int:SOX15
InteractionMYCN interactions

ATXN2L CASC3 ARID1B SEC31A AMOTL2 ARID1A SNRPB2 TFG ATXN2 SS18 ZC3H4 VPS13C LOXL1

1.02e-0713733313int:MYCN
InteractionEYA4 interactions

FOXJ2 NCOA2 ATXN2L NCOA3 R3HDM2 TAB3 GPS2

1.11e-07243337int:EYA4
InteractionMEX3A interactions

CASC3 R3HDM2 AMOTL2 ARID1A SS18 ZC3H4 LOXL2 TRPS1

1.48e-07384338int:MEX3A
InteractionCRX interactions

NCOA2 NCOA3 ARID1B ARID1A TFG HGS TRPS1

1.50e-07254337int:CRX
InteractionSOX7 interactions

NCOA2 NCOA3 ARID1B ARID1A TRPS1

2.14e-0782335int:SOX7
InteractionHNF4A interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 GPS2 TRPS1

2.57e-07275337int:HNF4A
InteractionFOXI1 interactions

NCOA3 ARID1B ARID1A HGS TRPS1

3.81e-0792335int:FOXI1
InteractionALG13 interactions

NCOA2 NCOA3 R3HDM2 ARID1B ARID1A ATXN2

4.67e-07183336int:ALG13
InteractionSP7 interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 GPS2 TRPS1

5.06e-07304337int:SP7
InteractionNFIA interactions

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

5.47e-07188336int:NFIA
InteractionHNF1B interactions

NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

5.81e-07190336int:HNF1B
InteractionMYOD1 interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 TRPS1

6.57e-07194336int:MYOD1
InteractionKLF5 interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 TRPS1

6.77e-07195336int:KLF5
InteractionPDCD6 interactions

ARID1B SEC31A PDCD6IP ARID1A TFG DROSHA

8.81e-07204336int:PDCD6
InteractionTBR1 interactions

NCOA2 NCOA3 ARID1B ARID1A TRPS1

1.06e-06113335int:TBR1
InteractionMCRIP2 interactions

ATXN2L CASC3 R3HDM2 ATXN2

1.41e-0651334int:MCRIP2
InteractionERG interactions

NCOA2 NCOA3 ARID1B ARID1A SS18 TRPS1

1.48e-06223336int:ERG
InteractionEYA2 interactions

ARID1B ARID1A TFG HGS TRPS1

1.49e-06121335int:EYA2
InteractionTNIP2 interactions

NCOA2 ATXN2L CASC3 ARID1B TSC22D2 AMOTL2 PDCD6IP TFG ATXN2 ZC3H4

1.81e-069523310int:TNIP2
InteractionTPRX2 interactions

NCOA2 ARID1B ARID1A GPS2

2.06e-0656334int:TPRX2
InteractionTLE3 interactions

FOXJ2 NCOA2 NCOA3 ARID1B ARID1A GPS2 TRPS1

2.09e-06376337int:TLE3
InteractionVPS37C interactions

PDCD6IP TFG PLSCR1 HGS GPS2

3.16e-06141335int:VPS37C
InteractionTFG interactions

R3HDM2 SEC31A PDCD6IP TFG PLSCR1 HGS

3.44e-06258336int:TFG
InteractionWWTR1 interactions

NCOA2 ATXN2L ARID1B AMOTL2 ARID1A TJP1 TAB3

4.48e-06422337int:WWTR1
InteractionGCM1 interactions

NCOA3 ARID1B ARID1A SS18

4.51e-0668334int:GCM1
InteractionNUP35 interactions

NCOA2 NCOA3 ARID1B PDCD6IP ARID1A TFG ATXN2

4.62e-06424337int:NUP35
InteractionSMARCE1 interactions

NCOA2 NCOA3 ARID1B AMOTL2 ARID1A SS18

6.35e-06287336int:SMARCE1
InteractionLHX4 interactions

NCOA2 ARID1B ARID1A GPS2 TRPS1

7.03e-06166335int:LHX4
InteractionEGR2 interactions

NCOA2 NCOA3 ARID1B ARID1A TRPS1

8.12e-06171335int:EGR2
InteractionEP300 interactions

NCOA2 CASC3 NCOA3 SEC31A BSN ARID1A SNRPB2 SS18 ZC3H4 PLSCR1 GPS2

8.18e-0614013311int:EP300
InteractionRNF4 interactions

FOXJ2 ATXN2L ARID1B TFG ATXN2 TJP1 NDUFB8 PLSCR1 TAB3 HGS TRPS1

8.81e-0614123311int:RNF4
InteractionTLX1 interactions

NCOA2 NCOA3 ARID1B ARID1A TRPS1

9.09e-06175335int:TLX1
InteractionSOX2 interactions

NCOA2 ATXN2L NCOA3 ARID1B AMOTL2 ARID1A SNRPB2 SS18 LOXL1 GPS2 TRPS1

9.43e-0614223311int:SOX2
InteractionPAX2 interactions

NCOA3 ARID1B GPS2 TRPS1

1.10e-0585334int:PAX2
InteractionIRF4 interactions

NCOA3 ARID1B ARID1A SS18

1.10e-0585334int:IRF4
InteractionDAZAP2 interactions

TFG LITAF PLSCR1 HGS GPS2

1.22e-05186335int:DAZAP2
InteractionCARM1 interactions

NCOA2 NCOA3 SEC31A PDCD6IP ARID1A DROSHA

1.29e-05325336int:CARM1
InteractionGATA2 interactions

NCOA3 ARID1B ARID1A SS18 TRPS1

1.69e-05199335int:GATA2
InteractionSOX9 interactions

NCOA3 ARID1B ARID1A TRPS1

1.85e-0597334int:SOX9
InteractionFEV interactions

NCOA2 NCOA3 ARID1B ARID1A TRPS1

1.86e-05203335int:FEV
InteractionNR3C1 interactions

FOXJ2 NCOA2 NCOA3 ARID1B BSN PDCD6IP ARID1A SS18 TRPS1

1.87e-05974339int:NR3C1
InteractionSS18L1 interactions

ARID1B ARID1A SS18 HGS

1.93e-0598334int:SS18L1
InteractionFMR1 interactions

NCOA2 ATXN2L CASC3 NCOA3 BSN ATXN2 TJP1

2.12e-05536337int:FMR1
InteractionAR interactions

NCOA2 NCOA3 ARID1B ARID1A TJP1 ZC3H4 VPS13C GPS2 TRPS1

2.16e-05992339int:AR
InteractionTRIM68 interactions

TFG TJP1 LOXL1 GPS2

2.17e-05101334int:TRIM68
InteractionNFIC interactions

NCOA3 ARID1B ARID1A GPS2 TRPS1

2.19e-05210335int:NFIC
InteractionPAX6 interactions

NCOA3 ARID1B ARID1A HGS GPS2 TRPS1

2.52e-05366336int:PAX6
InteractionPEF1 interactions

SEC31A PDCD6IP TFG HGS

2.83e-05108334int:PEF1
InteractionTHRA interactions

NCOA2 NCOA3 AMOTL2 GPS2

3.15e-05111334int:THRA
InteractionKLF3 interactions

ARID1B ARID1A SS18 GPS2 TRPS1

3.25e-05228335int:KLF3
InteractionNR5A2 interactions

NCOA2 NCOA3 GPS2

4.09e-0541333int:NR5A2
InteractionDDIT3 interactions

ARID1B AMOTL2 ARID1A SS18

4.28e-05120334int:DDIT3
InteractionETS1 interactions

NCOA3 ARID1B ARID1A TRPS1

4.42e-05121334int:ETS1
InteractionYWHAH interactions

NCOA2 ATXN2L CASC3 NCOA3 R3HDM2 AMOTL2 PDCD6IP TJP1 TAB3

4.95e-051102339int:YWHAH
InteractionR3HDM2 interactions

CASC3 R3HDM2 TFG ATXN2

5.68e-05129334int:R3HDM2
InteractionPPIA interactions

ARID1B SEC31A PDCD6IP ARID1A TFG ZC3H4 LOXL2 HGS

7.15e-05888338int:PPIA
InteractionNFIB interactions

NCOA3 ARID1B ARID1A TRPS1

8.25e-05142334int:NFIB
InteractionDAZL interactions

ATXN2L CASC3 R3HDM2 ATXN2

8.94e-05145334int:DAZL
InteractionSUMO1 interactions

NCOA2 NCOA3 TJP1 HGS TRPS1

9.68e-05287335int:SUMO1
InteractionPRMT1 interactions

NCOA2 ATXN2L NCOA3 SNRPB2 TFG ATXN2 ZC3H4 TAB3

9.81e-05929338int:PRMT1
InteractionTLX3 interactions

NCOA2 NCOA3 ARID1B ARID1A TRPS1

1.03e-04291335int:TLX3
InteractionPOU2AF1 interactions

TFG HGS GPS2

1.05e-0456333int:POU2AF1
InteractionARID2 interactions

ARID1B TSC22D2 ARID1A SS18

1.10e-04153334int:ARID2
InteractionTSG101 interactions

PDCD6IP TFG ATXN2 LITAF HGS

1.25e-04303335int:TSG101
InteractionSAP18 interactions

CASC3 NCOA3 TSC22D2 ARID1A SNRPB2

1.29e-04305335int:SAP18
InteractionKLF4 interactions

NCOA3 ARID1B ARID1A HGS

1.31e-04160334int:KLF4
InteractionPPARG interactions

NCOA2 NCOA3 ARID1B GPS2 TRPS1

1.33e-04307335int:PPARG
InteractionPTPN23 interactions

ATXN2L PDCD6IP ATXN2 HGS

1.37e-04162334int:PTPN23
InteractionFLI1 interactions

ARID1B ARID1A SS18

1.42e-0462333int:FLI1
InteractionFOS interactions

NCOA2 NCOA3 ARID1B ARID1A SS18

1.43e-04312335int:FOS
InteractionLSM12 interactions

ATXN2L CASC3 R3HDM2 ATXN2

1.44e-04164334int:LSM12
InteractionMECP2 interactions

ATXN2L ARID1B SEC31A PDCD6IP ARID1A SNRPB2 TJP1 ZC3H4 DROSHA

1.64e-041287339int:MECP2
InteractionMAP3K7CL interactions

TAB3 GPS2

1.70e-0412332int:MAP3K7CL
InteractionBICRA interactions

ARID1B ARID1A SS18

1.78e-0467333int:BICRA
InteractionARID1B interactions

NCOA3 ARID1B ARID1A SS18

1.93e-04177334int:ARID1B
InteractionTP53BP1 interactions

NCOA3 ARID1B ARID1A ZC3H4 HGS TRPS1

2.01e-04533336int:TP53BP1
InteractionATXN1 interactions

ATXN2L R3HDM2 SEC31A PDCD6IP ARID1A ATXN2 LITAF LOXL1

2.13e-041039338int:ATXN1
InteractionLHX2 interactions

ARID1B ARID1A SS18 TRPS1

2.19e-04183334int:LHX2
InteractionNEDD4 interactions

AMOTL2 PDCD6IP ARID1A LITAF PLSCR1 HGS

2.24e-04544336int:NEDD4
InteractionATG5 interactions

BSN ATXN2 TJP1 VPS13C TAB3

2.26e-04344335int:ATG5
InteractionTHRB interactions

NCOA2 NCOA3 BSN GPS2

2.33e-04186334int:THRB
InteractionGATA3 interactions

NCOA3 ARID1B ARID1A TRPS1

2.38e-04187334int:GATA3
InteractionCELA2A interactions

PDCD6IP HGS

3.08e-0416332int:CELA2A
InteractionFOXJ2 interactions

FOXJ2 NCOA2 TRPS1

3.13e-0481333int:FOXJ2
InteractionKHDRBS1 interactions

ATXN2L ATXN2 TJP1 DROSHA LOXL2

3.28e-04373335int:KHDRBS1
InteractionSTK11IP interactions

ARID1B ARID1A SS18

3.36e-0483333int:STK11IP
InteractionNR0B2 interactions

NCOA3 PLSCR1 GPS2

3.36e-0483333int:NR0B2
InteractionIRF1 interactions

ARID1B ARID1A SS18

3.36e-0483333int:IRF1
InteractionR3HDM1 interactions

R3HDM2 ATXN2 LITAF

3.48e-0484333int:R3HDM1
GeneFamilyAT-rich interaction domain containing

ARID1B ARID1A

9.75e-0515182418
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 NCOA3

1.26e-0417182486
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 ATXN2

2.77e-0425182775
GeneFamilyBasic helix-loop-helix proteins

NCOA2 NCOA3

5.27e-03110182420
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP

ATXN2L TJP1 ZC3H4 LITAF GPS2

4.79e-06199335M5203
CoexpressionRUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP

FOXJ2 NCOA3 PDCD6IP TFG LITAF

6.37e-05341335M12636
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA2 NCOA3 R3HDM2 TSC22D2 ATXN2 ZC3H4 PLSCR1

7.86e-05856337M4500
CoexpressionDELACROIX_RARG_BOUND_MEF

ATXN2 NDUFB8 PLSCR1 LOXL1 LOXL2

8.89e-05366335M2461
CoexpressionDELACROIX_RARG_BOUND_MEF

ATXN2 NDUFB8 PLSCR1 LOXL1 LOXL2

1.03e-04378335MM1077
CoexpressionGSE14769_40MIN_VS_360MIN_LPS_BMDM_DN

FOXJ2 ARID1A ZC3H4 PLSCR1

1.11e-04199334M3517
CoexpressionGSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP

AMOTL2 LITAF PLSCR1 HGS

1.13e-04200334M7754
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP

LITAF LOXL1 HGS GPS2

1.13e-04200334M5211
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 R3HDM2 ARID1B ARID1A ATXN2

2.47e-07186335de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 R3HDM2 ARID1B ARID1A ATXN2

2.47e-071863350b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

SEC31A TFG TJP1 VPS13C

1.35e-0519833476d40b8c2f8399725b3a62ee2ae0896559cf91eb
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 AMOTL2 ARID1A SS18 ZC3H4 TRPS1

1.82e-071763367499_DN
DrugDOPAC

HGD CASC3 LOXL1 LOXL2 STATH

5.60e-07112335CID000000547
Drugactinorhodin

HGD NCOA3 DROSHA STATH

1.68e-0660334CID005280985
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 AMOTL2 ARID1A ZC3H4 TRPS1

4.64e-061723351072_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

FOXJ2 NCOA2 ARID1A NDUFB8 ZC3H4

5.05e-061753356891_DN
Drugtrichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 AMOTL2 ARID1A ZC3H4 TRPS1

5.19e-06176335981_DN
Drugtrichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 AMOTL2 ARID1A ZC3H4 TRPS1

5.34e-06177335873_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 AMOTL2 ARID1A ZC3H4 TRPS1

5.49e-061783351471_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 AMOTL2 ARID1A ZC3H4 TRPS1

5.95e-061813356951_DN
Drugtyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA

NCOA2 NCOA3 TSC22D2 ARID1A ZC3H4

6.62e-061853351114_DN
Drugiprindole

BSN LOXL1 LOXL2

8.87e-0628333CID000021722
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; HL60; HT_HG-U133A

NCOA2 NCOA3 TSC22D2 SS18 TRPS1

8.98e-061973352463_DN
Drugamfonelic acid

BSN LOXL1 LOXL2

9.88e-0629333CID000002137
Drugamiguanidine

LOXL1 LOXL2

2.03e-055332CID000364439
DrugMctp

TJP1 LOXL1 LOXL2

2.08e-0537333CID000129268
Drugtopa quinone

HGD LOXL1 LOXL2

2.64e-0540333CID000123871
Drug1-benzyl-2-methyl-5-methoxytryptamine

LOXL1 LOXL2

3.04e-056332CID000009925
Drugbutamben

NCOA2 NCOA3

3.04e-056332ctd:C004605
DrugBU99006

LOXL1 LOXL2

3.04e-056332CID006603748
Drug5-hydroxyisatin

LOXL1 LOXL2

3.04e-056332CID010352011
DrugT 794

LOXL1 LOXL2

3.04e-056332CID003077680
DrugNSD 2023

LOXL1 LOXL2

3.04e-056332CID000019831
Drug1-PCPA

LOXL1 LOXL2

3.04e-056332CID000194548
DrugN-cyclopropyl-5,6-dimethoxytryptamine

LOXL1 LOXL2

3.04e-056332CID000156277
DrugN-cyclopropyl-6,7-dimethoxytryptamine

LOXL1 LOXL2

3.04e-056332CID000156278
DrugN-cyclopropyl-alpha-methylbenzylamine

LOXL1 LOXL2

3.04e-056332CID000362778
Drugbromfenacoum

ATXN2L BSN PDCD6IP ATXN2 TJP1 NDUFB8 HGS

3.16e-05644337ctd:C013418
Drug4-hydroxyphenylacetic acid

HGD LOXL1 LOXL2

3.29e-0543333CID000000127
Drugdimethylphenethylamine

LOXL1 LOXL2

4.26e-057332CID000025124
DrugBU 224

LOXL1 LOXL2

4.26e-057332CID000002457
DrugM 2113

LOXL1 LOXL2

4.26e-057332CID000072895
DrugN-(2-aminoethyl)benzamide

LOXL1 LOXL2

4.26e-057332CID000423156
Drugcimoxatone

LOXL1 LOXL2

4.26e-057332CID000052542
Drugiproclozide

LOXL1 LOXL2

4.26e-057332CID000019063
Drugbrofaromine

LOXL1 LOXL2

4.26e-057332CID000044570
Drugtetrahydroharmine

LOXL1 LOXL2

4.26e-057332CID000159809
Drug4'-amino-MPTP

LOXL1 LOXL2

4.26e-057332CID000086263
Drug4-methoxytranylcypromine

LOXL1 LOXL2

4.26e-057332CID003082143
Drug1-Phenylcyclobutylamine

LOXL1 LOXL2

4.26e-057332CID000152214
DrugJB 835

LOXL1 LOXL2

4.26e-057332CID000152988
Drug1-benzylcyclopropylamine

LOXL1 LOXL2

4.26e-057332CID000152923
DrugRS-2232

LOXL1 LOXL2

4.26e-057332CID000134882
DrugSR 95191

LOXL1 LOXL2

4.26e-057332CID000072119
Drugp-dimethylaminomethylbenzylamine

LOXL1 LOXL2

4.26e-057332CID000193714
DrugMPTP-3-ol

LOXL1 LOXL2

4.26e-057332CID000100194
DrugAC1O5VTH

LOXL1 LOXL2

5.67e-058332CID006441710
DrugAC1Q6B1A

LOXL1 LOXL2

5.67e-058332CID000088562
Drug4-chlorobenzylamine

LOXL1 LOXL2

5.67e-058332CID000066036
Drugamezinium

LOXL1 LOXL2

5.67e-058332CID000071926
Drugmebanazine

LOXL1 LOXL2

5.67e-058332CID000006179
Drugmofegiline

LOXL1 LOXL2

5.67e-058332CID006437850
Drugpyrazidol

LOXL1 LOXL2

5.67e-058332CID000068802
Drug4-fluorotranylcypromine

LOXL1 LOXL2

5.67e-058332CID003082666
Drugranbezolid

LOXL1 LOXL2

5.67e-058332CID000496993
Drug2-propyl-pentylamine

LOXL1 LOXL2

5.67e-058332CID000170419
DrugQ 192

LOXL1 LOXL2

5.67e-058332CID000077317
Drugbenzylamine

HGD LOXL1 LOXL2

5.84e-0552333CID000007504
Drugbenzalkonium

LOXL1 LOXL2 HGS STATH

6.06e-05148334CID000007681
DrugLilly 51641

LOXL1 LOXL2

7.29e-059332CID000021485
Drug3-amino-2-oxazolidinone

LOXL1 LOXL2

7.29e-059332CID000065725
Drugtoloxatone

LOXL1 LOXL2

7.29e-059332CID000034521
DrugMDL 72392

LOXL1 LOXL2

7.29e-059332CID006439254
DrugAC1L4KA6

LOXL1 LOXL2

7.29e-059332CID000158620
DrugAC1L1BMC

LOXL1 LOXL2

7.29e-059332CID000001500
DrugFLA 336

LOXL1 LOXL2

7.29e-059332CID000123706
DrugRS-8359

LOXL1 LOXL2

7.29e-059332CID000164116
Drugpinoline

LOXL1 LOXL2

7.29e-059332CID000001868
DrugRo 16-6491

LOXL1 LOXL2

7.29e-059332CID000004289
DrugFLA 365

LOXL1 LOXL2

7.29e-059332CID000072776
DrugJ 508

LOXL1 LOXL2

7.29e-059332CID000155219
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

8.81e-051633347453_DN
DrugEXP 561

LOXL1 LOXL2

9.10e-0510332CID000027696
DrugU-0521

LOXL1 LOXL2

9.10e-0510332CID000021632
Drugacetylcadaverine

LOXL1 LOXL2

9.10e-0510332CID000189087
DrugMonase

LOXL1 LOXL2

9.10e-0510332CID000008366
Drug3-dimethylamino-1-propyne

LOXL1 LOXL2

9.10e-0510332CID000081643
Drugthallium acetate

BSN STATH

9.10e-0510332CID000011247
DrugN-cyclopropylbenzylamine

LOXL1 LOXL2

9.10e-0510332CID000025866
Drugsafrazine

LOXL1 LOXL2

9.10e-0510332CID000034041
DrugNmiQ

LOXL1 LOXL2

9.10e-0510332CID000019850
DrugNSC-169892

LOXL1 LOXL2

9.10e-0510332CID000043479
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A LOXL1 TRPS1

9.46e-051663347324_DN
DrugPh(2

TFG TJP1 DROSHA

9.90e-0562333CID006432095
Drugmoclobemide

LOXL1 LOXL2 HGS

9.90e-0562333CID000004235
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

9.90e-051683343868_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

NCOA2 ARID1A ZC3H4 TRPS1

1.04e-041703341050_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

NCOA2 ARID1A ZC3H4 TRPS1

1.06e-041713341000_DN
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

NCOA2 NCOA3 ATXN2 TRPS1

1.06e-041713347535_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.08e-041723343428_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.08e-041723346993_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.08e-041723342794_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.11e-041733345987_DN
Drugbefloxatone

LOXL1 LOXL2

1.11e-0411332CID000060824
Drug4-hydroxy-3-methoxyphenylglycol-piperazine

LOXL1 LOXL2

1.11e-0411332CID002723890
DrugNSC55260

LOXL1 LOXL2

1.11e-0411332CID005356351
Drug2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3

NCOA2 NCOA3

1.11e-0411332ctd:C061137
DrugAmiflamina

LOXL1 LOXL2

1.11e-0411332CID000071221
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.13e-041743346579_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.13e-041743341659_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 ARID1A ZC3H4 TRPS1

1.13e-041743345945_DN
Diseasetestosterone measurement

ATXN2L CASC3 R3HDM2 ARID1B TSC22D2 ARID1A SS18 ZC3H4 LITAF TRPS1

8.16e-0712753310EFO_0004908
Diseasespinocerebellar ataxia type 2 (implicated_via_orthology)

ATXN2L ATXN2

1.21e-062332DOID:0050955 (implicated_via_orthology)
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1B ARID1A

1.21e-055332C3281201
Diseaseapolipoprotein A 1 measurement

NCOA2 R3HDM2 TSC22D2 ARID1A ATXN2 ZC3H4 TRPS1

3.51e-05848337EFO_0004614
Diseaseneuroblastoma (is_implicated_in)

ARID1B ARID1A

5.43e-0510332DOID:769 (is_implicated_in)
DiseaseHMG CoA reductase inhibitor use measurement

TSC22D2 ARID1A LITAF TRPS1

5.77e-05189334EFO_0009932
Diseaseglucose measurement

R3HDM2 BSN ATXN2 ZC3H4 VPS13C

6.09e-05380335EFO_0004468
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ATXN2L ATXN2

7.95e-0512332DOID:1441 (implicated_via_orthology)
Diseaseapolipoprotein B measurement

R3HDM2 ARID1A ATXN2 LITAF GPS2 TRPS1

8.31e-05663336EFO_0004615
DiseaseCoffin-Siris syndrome

ARID1B ARID1A

9.39e-0513332C0265338
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

R3HDM2 TSC22D2 ARID1A TRPS1

1.11e-04224334EFO_0004530, EFO_0008317
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

R3HDM2 ARID1A ATXN2 TRPS1

1.11e-04224334EFO_0004574, EFO_0008317
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

R3HDM2 ARID1A ATXN2 TRPS1

1.13e-04225334EFO_0008317, EFO_0010351
Diseasenon-high density lipoprotein cholesterol measurement

R3HDM2 ARID1A ATXN2 ZC3H4 LITAF TRPS1

1.24e-04713336EFO_0005689
Diseasesexual dimorphism measurement

ATXN2L BSN ARID1A ZC3H4 LOXL1 LOXL2 TRPS1

1.85e-041106337EFO_0021796
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

R3HDM2 ARID1A TRPS1

2.34e-04107333EFO_0004614, EFO_0004615
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

R3HDM2 TSC22D2 ATXN2 TRPS1

2.48e-04276334EFO_0004612, EFO_0020943
DiseaseBreast Carcinoma

NCOA2 NCOA3 ARID1B ARID1A LOXL2

3.08e-04538335C0678222
Diseaseserum alanine aminotransferase measurement

ATXN2L TSC22D2 ARID1A ATXN2 ZC3H4 TRPS1

3.60e-04869336EFO_0004735
Diseaseneuroticism measurement, cognitive function measurement

ATXN2L R3HDM2 TSC22D2 ARID1A TRPS1

3.88e-04566335EFO_0007660, EFO_0008354
Diseasecholesteryl ester measurement, high density lipoprotein cholesterol measurement

TSC22D2 ARID1A ATXN2 TRPS1

3.94e-04312334EFO_0004612, EFO_0010351
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

TSC22D2 ARID1A ATXN2 TRPS1

4.08e-04315334EFO_0004574, EFO_0004612
DiseaseBilateral Wilms Tumor

ARID1A DROSHA

4.83e-0429332C2930471
Diseaselung non-small cell carcinoma (is_implicated_in)

NCOA2 ARID1B ARID1A

5.03e-04139333DOID:3908 (is_implicated_in)
Diseasegrip strength measurement

ATXN2L ZC3H4 LOXL1 TRPS1

6.07e-04350334EFO_0006941
Diseaseglaucoma

TSC22D2 ATXN2 LOXL1

6.78e-04154333MONDO_0005041
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

ATXN2L TSC22D2 ZC3H4 TRPS1

7.03e-04364334EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseNephroblastoma

ARID1A DROSHA

7.46e-0436332C0027708
Diseasealcohol consumption measurement, high density lipoprotein cholesterol measurement

R3HDM2 ARID1A TRPS1

7.85e-04162333EFO_0004612, EFO_0007878
Diseasesex interaction measurement, Crohn's disease

BSN LITAF

7.88e-0437332EFO_0000384, EFO_0008343
Diseasehematocrit

R3HDM2 ARID1B BSN ATXN2 ZC3H4 TRPS1

7.99e-041011336EFO_0004348
Diseasealcohol drinking, high density lipoprotein cholesterol measurement

R3HDM2 ARID1A TRPS1

8.72e-04168333EFO_0004329, EFO_0004612
Diseaseanthropometric measurement

BSN ATXN2 LOXL1

8.72e-04168333EFO_0004302
Diseasereticulocyte count

TSC22D2 AMOTL2 BSN ATXN2 ZC3H4 TRPS1

9.49e-041045336EFO_0007986
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1B ARID1A

9.68e-0441332C0496956
DiseaseBreast adenocarcinoma

ARID1B ARID1A

9.68e-0441332C0858252
Diseasereticulocyte measurement

TSC22D2 AMOTL2 BSN ATXN2 ZC3H4 TRPS1

9.87e-041053336EFO_0010700
Diseasecolorectal cancer, endometrial neoplasm

ATXN2 LITAF

1.02e-0342332EFO_0004230, MONDO_0005575
Diseasespleen volume

ATXN2 TJP1

1.06e-0343332EFO_0600047
Diseasecoffee consumption measurement, tea consumption measurement

ATXN2 ZC3H4

1.11e-0344332EFO_0006781, EFO_0010091

Protein segments in the cluster

PeptideGeneStartEntry
QYQYLQQSQEHPPPP

AMOTL2

261

Q9Y2J4
FPAVQYLSQPQPQPY

GPS2

216

Q13227
CQQGQQPYYSQQPQP

ARID1B

676

Q8NFD5
SYIPYNPQQFPGQPA

ATXN2L

786

Q8WWM7
QPPQQIQVSYYPPGQ

R3HDM2

511

Q9Y2K5
YPPGQYPNSNQQYRP

R3HDM2

521

Q9Y2K5
YYTQPAPIPNNNPIT

LITAF

61

Q99732
YNQQSPHPQQQQPPY

ARID1A

471

O14497
QSQPPYSQPQAQSPY

ARID1A

546

O14497
TQYVAYSPQQFPNQP

ATXN2

1036

Q99700
TYRQQPSYPQQFPYP

LOXL1

166

Q08397
YFQQPAPEYHQPQAP

LOXL2

36

Q9Y4K0
FQQPRFQPPAPQYSA

BSN

3051

Q9UPA5
QPSYPFPQPPQQSYY

PDCD6IP

851

Q8WUM4
FPVPNQPVYNQPVYN

PLSCR1

61

O15162
QPVYNQPVYNQPVGA

PLSCR1

66

O15162
NYYMYQQQQPPPPQQ

FOXJ2

286

Q9P0K8
PVYQPVGPKQYPYNN

NDUFB8

151

O95169
PPQALNAYYLPNKNQ

ECEL1

566

O95672
YYNPAQQQVQPKPSP

CASC3

666

O15234
NPQVPDYPPNYILFL

SNRPB2

141

P08579
PEGQNNPQVCPYNLY

HGD

26

Q93099
LLHPQQPPVQYQYEP

DROSHA

41

Q9NRR4
QPLYPQPYQPQYQQY

STATH

46

P02808
AQQPQQFAYPQPQIP

TSC22D2

351

O75157
LPVYPHQQNYQPSQY

TAB3

266

Q8N5C8
MPQAPPQQFPYQPNY

NCOA3

1301

Q9Y6Q9
IPQANAQQFPFPPNY

NCOA2

1291

Q15596
NPCQNYVPYPTFNLP

TRPS1

1136

Q9UHF7
LPAQPPQQYQASNYP

TFG

311

Q92734
PQQGYPPQQQQYPGQ

SS18

341

Q15532
PPQQPYIAGQQPMYQ

HGS

726

O14964
GNIPPNYQYIFQPIS

VPS13C

286

Q709C8
PPIPPAQNFYENFYQ

ZC3H4

686

Q9UPT8
ENQTYPPYSPQAQPQ

TJP1

891

Q07157
VQTQQYYPHGENPPP

SEC31A

826

O94979