Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	KIF23 KIF26B DNAH2 DNAH17 KIF28P	6.39e-05	70	120	5	GO:0003777
MousePheno	abnormal spermiogenesis	SPATA46 MKRN2 DNAH2 AXDND1 LRGUK NF1 STYX BAZ1A DNAH17 TEX44	3.47e-06	237	92	10	MP:0001932
MousePheno	teratozoospermia	SPATA46 MKRN2 DNAH2 AXDND1 LRGUK NF1 STYX BAZ1A TTC29 DNAH17 C2CD6 TEX44	1.43e-05	408	92	12	MP:0005578
MousePheno	abnormal sperm head morphology	SPATA46 MKRN2 DNAH2 AXDND1 LRGUK NF1 STYX BAZ1A DNAH17	5.40e-05	261	92	9	MP:0009230
MousePheno	abnormal spermiation	MKRN2 LRGUK NF1 BAZ1A	5.49e-05	32	92	4	MP:0004182
MousePheno	asthenozoospermia	MKRN2 DNAH2 OR4M1 LRGUK STYX BAZ1A TTC29 DNAH17 C2CD6 TEX44	1.31e-04	362	92	10	MP:0002675
MousePheno	abnormal sperm physiology	MKRN2 DNAH2 OR4M1 LRGUK STYX BAZ1A TTC29 DNAH17 C2CD6 FER1L5 TEX44	1.65e-04	447	92	11	MP:0004543
Domain	CRAL_TRIO_2	MCF2L2 NF1 MCF2L	4.80e-05	12	115	3	PF13716
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	1.24e-05	2	123	2	10441747
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	1.24e-05	2	123	2	16416087
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	1.24e-05	2	123	2	32081420
Pubmed	Tissue and zonal-specific expression of an olfactory receptor transgene.	OR10H4 OR10H3	1.24e-05	2	123	2	9412503
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	1.24e-05	2	123	2	7524912
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	1.24e-05	2	123	2	9060413
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1B WDR7 AHCYL2 ZEB2 ZNF644 BRINP2 DLG3 MCF2L PLCE1	1.53e-05	407	123	9	12693553
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RNGTT CPD GLMN PPP1R10 STYX SSH1 MKI67 UBR3 HADHB CKAP2 CDC25A AJUBA ANKRD52 PLK4	2.16e-05	1049	123	14	27880917
Pubmed	IL-6/IL-12 Cytokine Receptor Shuffling of Extra- and Intracellular Domains Reveals Canonical STAT Activation via Synthetic IL-35 and IL-39 Signaling.	IL12RB1 IL6R	3.71e-05	3	123	2	29123149
Pubmed	Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.	RPS6KA1 NF1	3.71e-05	3	123	2	34021083
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	3.71e-05	3	123	2	7544442
Pubmed	PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart.	SSH1 PLCE1	3.71e-05	3	123	2	24345679
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5C KDM5D	7.41e-05	4	123	2	16541399
Pubmed	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.	KDM5C KDM5D	7.41e-05	4	123	2	17320160
Pubmed	A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.	KDM5C KDM5D	7.41e-05	4	123	2	7951230
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM5C KDM5D	7.41e-05	4	123	2	32732223
Pubmed	SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.	NF1 MKI67	1.84e-04	6	123	2	22118770
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF23 KIF26B NCKIPSD RFX7 NF1 SLF2 AASS CEP95 CKAP2 PLK4 USP6NL	2.50e-04	861	123	11	36931259
Pubmed	Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.	RPS6KA1 NF1 DLG3 NANOS1	2.53e-04	86	123	4	10862698
Pubmed	Grainyhead-like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice.	MKI67 GRHL3	2.58e-04	7	123	2	27907249
Pubmed	Genetic mapping and systematic screening of mouse endogenously imprinted loci detected with restriction landmark genome scanning method (RLGS).	PGM3 GSTA5	2.58e-04	7	123	2	7894162
Pubmed	Quantitative trait loci in Chromosomes 3, 8, and 9 regulate antibody production against Salmonella flagellar antigens in the mouse.	IL12RB1 IL6R	2.58e-04	7	123	2	15457342
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH2 DNAH17	2.58e-04	7	123	2	31178125
Pubmed	Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes.	NAT1 ABCB1	3.43e-04	8	123	2	17259654
Pubmed	Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping.	MKI67 PRDM16	3.43e-04	8	123	2	28424158
Pubmed	P311 regulates distal lung development via its interaction with several binding proteins.	FBN2 TNXB	3.43e-04	8	123	2	32682987
Pubmed	Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects.	MKI67 GRHL3	3.43e-04	8	123	2	36606449
Pubmed	The use of restriction landmark genomic scanning to scan the mouse genome for endogenous loci with imprinted patterns of methylation.	PGM3 GSTA5	3.43e-04	8	123	2	7774561
Pubmed	Ezh2-dependent methylation in oral epithelia promotes secondary palatogenesis.	MKI67 GRHL3	4.39e-04	9	123	2	37435868
Pubmed	Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations.	SSH1 MKI67	4.39e-04	9	123	2	27588418
Pubmed	The Metabolite Saccharopine Impairs Neuronal Development by Inhibiting the Neurotrophic Function of Glucose-6-Phosphate Isomerase.	AASS MKI67	4.39e-04	9	123	2	35135854
Pubmed	KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development.	KIF23 MKI67	4.39e-04	9	123	2	30006548
Pubmed	In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.	NF1 MKI67	4.39e-04	9	123	2	22918885
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	NAT1 TAF1A CPD TSFM DNAJC10 BAZ1A AASS GORASP1 MSL3 IFT80 MCF2L	4.58e-04	925	123	11	28986522
Pubmed	Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.	KIF23 MKI67 CDC25A	4.80e-04	43	123	3	30733279
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	WDR7 CPD DNAJC10 DENND5A AP3D1 USP6NL	5.48e-04	285	123	6	34369648
Pubmed	Grhl3 and Lmo4 play coordinate roles in epidermal migration.	MKI67 GRHL3	5.48e-04	10	123	2	18619436
Pubmed	Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.	MKI67 PRDM16	5.48e-04	10	123	2	22859371
Pubmed	Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice.	LETMD1 PRDM16	5.48e-04	10	123	2	37353518
Pubmed	Mapping of class alpha glutathione S-transferase 2 (GST-2) genes to the vicinity of the d locus on mouse chromosome 9.	PGM3 GSTA5	5.48e-04	10	123	2	1981995
Pubmed	Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma.	MKI67 GRHL3	6.68e-04	11	123	2	26063791
Pubmed	IRF6 expression in basal epithelium partially rescues Irf6 knockout mice.	MKI67 GRHL3	6.68e-04	11	123	2	28643456
Pubmed	Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.	HECTD4 PLCE1	6.68e-04	11	123	2	21642993
Pubmed	The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.	MKI67 GRHL3	6.68e-04	11	123	2	31578523
Pubmed	Oxidative stress regulates progenitor behavior and cortical neurogenesis.	MKI67 PRDM16	6.68e-04	11	123	2	32041791
Pubmed	A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis.	MKI67 NANOS1	6.68e-04	11	123	2	26609159
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	AMPD1 DRP2 SLC25A14 RGS8 FBN2 TTC29 MSL3 TRPM1 IL6R	6.78e-04	674	123	9	37196079
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	AMPD1 MKRN2 LDHB FBN2 BAZ1A	6.97e-04	197	123	5	17500595
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RNGTT RPS6KA1 CPD PGM3 FBN2 STYX DNAJC10 SSH1 PIPSL CDC25A ANKRD52	7.01e-04	974	123	11	28675297
Pubmed	Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.	KDM5C MSL3	8.00e-04	12	123	2	23210685
Pubmed	A cochlear progenitor pool influences patterning of the mammalian sensory epithelium via MYBL2.	MKI67 PRDM16	8.00e-04	12	123	2	39254648
Pubmed	UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex.	SLC25A14 MKI67	8.00e-04	12	123	2	28276603
Pubmed	Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.	NF1 MKI67	8.00e-04	12	123	2	22789544
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CPD NDUFA10 PGM3 GLMN PPP1R10 BAZ1A HADHB CKAP2	8.78e-04	560	123	8	35241646
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	KDM5C CPD ABCB1 NF1 DNAJC10 HADHB	8.92e-04	313	123	6	38270169
Pubmed	Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway.	MKI67 IL6R	9.43e-04	13	123	2	24209760
Pubmed	Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.	KDM5C KDM5D	9.43e-04	13	123	2	14660691
Pubmed	Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb.	ZEB2 MKI67	9.43e-04	13	123	2	32253238
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5C KDM5D	9.43e-04	13	123	2	24619213
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	KIF23 SETD1B RNGTT HECTD4 NF1 DNAJC10 MKI67	9.98e-04	440	123	7	34244565
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH2 DNAH17	1.10e-03	14	123	2	9373155
Pubmed	Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis.	ZEB2 MKI67	1.10e-03	14	123	2	26324903
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETD1B KDM5C KDM5D	1.10e-03	57	123	3	18022353
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	MKRN2 NCKIPSD POLR2M AHCYL2 GORASP1 BYSL AJUBA ANKRD52 AP3D1 ACAP3 FAM83A	1.17e-03	1038	123	11	26673895
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	SETD1B RNGTT KDM5C LDHB SLF2 ZNF644 PLPBP ANKRD52	1.20e-03	588	123	8	38580884
Pubmed	ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.	DRP2 ZEB2 TRPM1	1.21e-03	59	123	3	31924792
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	LETMD1 SLC25A14 NDUFA10 LDHB TSFM ABCB1 TMTC1 AASS NDUFAF7 PLPBP HADHB	1.26e-03	1047	123	11	18614015
Pubmed	Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.	SETD1B MKI67	1.26e-03	15	123	2	28619824
Pubmed	Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes.	NAT1 ABCB1	1.26e-03	15	123	2	20468060
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	KDM5C KDM5D	1.26e-03	15	123	2	14762062
Pubmed	A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis.	MKI67 AJUBA	1.26e-03	15	123	2	15630473
Pubmed	Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing.	DNAJC10 AP3D1	1.26e-03	15	123	2	19436707
Pubmed	Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.	MKI67 HADHB IL6R	1.34e-03	61	123	3	27694478
Pubmed	Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system.	ZEB2 MKI67	1.44e-03	16	123	2	22365546
Pubmed	Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in retina.	MKI67 TRPM1	1.44e-03	16	123	2	29559301
Pubmed	Transcriptional Regulator ZEB2 Is Essential for Bergmann Glia Development.	ZEB2 MKI67	1.44e-03	16	123	2	29326173
Pubmed	IRF6 and AP2A Interaction Regulates Epidermal Development.	MKI67 GRHL3	1.44e-03	16	123	2	29913133
Pubmed	Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis.	OR10H4 OR10H3	1.44e-03	16	123	2	17521568
Pubmed	Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.	NF1 MKI67	1.44e-03	16	123	2	28637693
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	KIF23 MCF2L2 AHCYL2 LDHB PPP1R10 BYSL PLPBP HADHB MCF2L AJUBA	1.58e-03	916	123	10	32203420
Pubmed	Interaction network of human early embryonic transcription factors.	RFX7 ZEB2 BAZ1A ZNF644 MKI67 PRDM16	1.60e-03	351	123	6	38297188
Pubmed	Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure.	ZEB2 GRHL3	1.63e-03	17	123	2	26903501
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	IL12RB1 DNAH2 HKDC1 AHCYL2 ZEB2 ABCB1 DNAJC10 BAZ1A TENM1 DLG3 HADHB MCF2L AP3D1	1.82e-03	1442	123	13	35575683
Pubmed	Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure.	KIF23 MKI67	1.83e-03	18	123	2	38505753
Pubmed	Hirschsprung Disease Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	ZEB2 NF1	1.83e-03	18	123	2	20301612
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	KDM5C KDM5D	1.83e-03	18	123	2	12023983
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	KIF23 MROH2A RTTN GLMN NDUFAF7 BYSL PIPSL	1.97e-03	496	123	7	31343991
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	SLF2 NDUFAF7 DLG3 MCF2L	1.98e-03	149	123	4	22664934
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	AMPD1 DRP2 DNAH2 NF1 AASS MCF2L FER1L5 ANKRD52	2.00e-03	638	123	8	31182584
Pubmed	Genes, plasticity and mental retardation.	NF1 DLG3	2.04e-03	19	123	2	18329113
Pubmed	PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.	MKI67 PRDM16	2.04e-03	19	123	2	33597191
Pubmed	A multifunctional protein, EWS, is essential for early brown fat lineage determination.	MKI67 PRDM16	2.04e-03	19	123	2	23987512
Pubmed	Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.	NF1 MKI67	2.04e-03	19	123	2	34428430
Pubmed	Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.	NF1 MKI67	2.04e-03	19	123	2	25535838
Pubmed	Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development.	MKI67 PRDM16	2.04e-03	19	123	2	25848030
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	CPD MKI67 TENM1 AP3D1 USP6NL	2.49e-03	263	123	5	34702444
Pubmed	Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.	ZEB2 MKI67	2.49e-03	21	123	2	27385012
Pubmed	A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.	MKI67 IFT80	2.49e-03	21	123	2	21703454
Pubmed	Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.	HECTD4 TNXB	2.49e-03	21	123	2	25249183
Pubmed	Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.	RPS6KA1 CPD AHCYL2 BYSL	2.56e-03	160	123	4	31678930
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF23 KIF26B KIF28P	9.16e-04	46	75	3	622
GeneFamily	AT-rich interaction domain containing	KDM5C KDM5D	1.72e-03	15	75	2	418
GeneFamily	Dyneins, axonemal	DNAH2 DNAH17	2.22e-03	17	75	2	536
GeneFamily	Atypical dual specificity phosphatases	RNGTT STYX	2.49e-03	18	75	2	896
Coexpression	GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP	LETMD1 LDHB GORASP1 MSL3 TENM1 HADHB DENND5A IL6R	4.57e-06	200	122	8	M9883
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MROH2A CCDC168 AHCYL2 MKI67 CKAP2 FAM83A	7.34e-06	168	123	6	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF23 ZEB2 MKI67 CKAP2 ANKRD52 PLK4	8.12e-06	171	123	6	e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell	367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF23 ZEB2 MKI67 CKAP2 ANKRD52 PLK4	8.12e-06	171	123	6	52fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 AXDND1 RGS8 MKI67 CKAP2 PLK4	8.97e-06	174	123	6	7b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 KCNH7 DRP2 CCDC168 MKI67 CKAP2	9.27e-06	175	123	6	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 KIF26B MROH2A FBN2 TENM1 PLCE1	1.23e-05	184	123	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 KIF26B MROH2A FBN2 TENM1 PLCE1	1.23e-05	184	123	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 KIF26B MROH2A FBN2 TENM1 PLCE1	1.23e-05	184	123	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-Dividing_AT2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	KIF23 KCNH7 WDR7 DLG3 USP6NL IL6R	1.97e-05	200	123	6	befc25cbcbac2c02e5fd33d6e78e59979050090c
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_E\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KDM5D AXDND1 RGS8 BRINP2 IMPG2	3.67e-05	135	123	5	35928195cf34f055b353562c96f451aef2344d64
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	DRP2 LDHB DIRAS3 C2CD6 IL6R	7.53e-05	157	123	5	c44bd530e396b08f16f284e185dcb830843959ea
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH2A SLC9B1 DNAH17 FAM83A	7.89e-05	82	123	4	73349906bcc8d1a40dc03df7a490a963e85564f2
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH2A SLC9B1 DNAH17 FAM83A	7.89e-05	82	123	4	15bc417aaace2b1d680904a622fe76e95083c9ff
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MROH2A SLC9B1 DNAH17 FAM83A	7.89e-05	82	123	4	697e1da3095c8483b8181b290fa5417bdc9cee54
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF23 MKI67 CKAP2 NANOS1 PLK4	8.48e-05	161	123	5	2165897924c790fec43502283f1df221c56c1e9f
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	AMPD1 TMEM72 TNXB IL6R PLCE1	8.73e-05	162	123	5	7f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF23 MKI67 CDC25A NANOS1 PLK4	9.52e-05	165	123	5	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 ZEB2 MKI67 IFT80 CKAP2	9.52e-05	165	123	5	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Lung / Manually curated celltypes from each tissue	KIF23 FBN2 MKI67 CKAP2 PLK4	1.01e-04	167	123	5	82739226347d74897be000f429b73543a031af96
ToppCell	10x5'-Lung-Hematopoietic_progenitors\|Lung / Manually curated celltypes from each tissue	KIF23 FBN2 MKI67 CKAP2 PLK4	1.01e-04	167	123	5	dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 WDFY4 BAZ1A MKI67 CKAP2	1.04e-04	168	123	5	b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 RTTN WDFY4 MKI67 CKAP2	1.04e-04	168	123	5	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT10 KIF23 MKI67 CKAP2 IL6R	1.06e-04	169	123	5	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC5A10 WDFY4 NPFFR2 CKAP2 PRDM16	1.09e-04	170	123	5	32917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL12RB1 KIF23 MKI67 PLK4 FAM83A	1.09e-04	170	123	5	6b91d4cbe0697b65bfb2e099e7a9b39ea2fba3a9
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A POLR3E MKI67 CKAP2 CDC25A	1.19e-04	173	123	5	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WDFY4 BAZ1A MKI67 DSEL CDC25A	1.22e-04	174	123	5	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 MKI67 BRINP2 AJUBA PLCE1	1.25e-04	175	123	5	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 DRP2 MKI67 CKAP2 PLK4	1.25e-04	175	123	5	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 DACT1 MKI67 CKAP2 AJUBA	1.25e-04	175	123	5	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 MKI67 BRINP2 AJUBA PLCE1	1.25e-04	175	123	5	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF23 KCNH7 MKI67 CKAP2 PLK4	1.25e-04	175	123	5	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF23 WDFY4 CKAP2 ANKRD52 PLK4	1.29e-04	176	123	5	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 RTTN DACT1 MKI67 CKAP2	1.32e-04	177	123	5	3e149bff1f1b393a7abe98984e37981c8296f95d
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 DACT1 MKI67 CKAP2 PLK4	1.32e-04	177	123	5	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	GALNT10 DRP2 KIF26B ZEB2 DACT1	1.36e-04	178	123	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 MKI67 CKAP2 TNXB PLCE1	1.36e-04	178	123	5	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-4\|TCGA-Endometrium / Sample_Type by Project: Shred V9	LRGUK DNAJC10 TTC29 FAM47E MAP3K19	1.47e-04	181	123	5	51d91b923920463245e95d65c6a5197e21d34d73
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 BAZ1A MKI67 ATP13A3 CKAP2	1.51e-04	182	123	5	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.51e-04	182	123	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NAT1 AASS TTC29 FAM47E	1.51e-04	97	123	4	031bc124739541b0b2591e1b6ef41f12adfd5c18
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NAT1 AASS TTC29 FAM47E	1.51e-04	97	123	4	0cd19f619f10a35d3107518aa83c0eda0572930a
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NAT1 AASS TTC29 FAM47E	1.51e-04	97	123	4	33330ac2de9e49d78b478f175068999235c9af25
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 MKI67 CKAP2 PLK4 IMPG2	1.58e-04	184	123	5	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.58e-04	184	123	5	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.63e-04	185	123	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA1 ST6GALNAC2 BRINP2 ATP13A3 MCF2L	1.67e-04	186	123	5	4ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC5A10 AOX1 TENM1 MCF2L IL6R	1.71e-04	187	123	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.71e-04	187	123	5	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC5A10 AOX1 TENM1 MCF2L IL6R	1.71e-04	187	123	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ZEB2 PPP1R10 NF1 ZNF644 ATP13A3	1.75e-04	188	123	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.75e-04	188	123	5	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	IL12RB1 ABCB1 GLMN POLR3E ALG12	1.75e-04	188	123	5	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.75e-04	188	123	5	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.80e-04	189	123	5	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF23 ZEB2 MKI67 CKAP2 PLK4	1.80e-04	189	123	5	d049f33115610bda4489968759f754730698b9cd
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.80e-04	189	123	5	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	NAT1 DNAH2 LRGUK TTC29 MAP3K19	1.80e-04	189	123	5	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HKDC1 ST6GALNAC2 FBN2 DNAH17 MCF2L	1.84e-04	190	123	5	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF23 FBN2 MKI67 CKAP2 PLK4	1.88e-04	191	123	5	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF23 FBN2 MKI67 CKAP2 PLK4	1.88e-04	191	123	5	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell	Dividing_Macrophages-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KIF23 MKI67 CKAP2 CDC25A PLK4	1.93e-04	192	123	5	741bd0c2b0a7ce3fcb1610ce8bdacaf9a803c212
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AOX1 ST6GALNAC2 CLIP4 DLG3 TNXB	1.98e-04	193	123	5	64edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF23 MKI67 CKAP2 CDC25A PLK4	1.98e-04	193	123	5	cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MCF2L2 WDFY4 ZEB2 CLIP4 DENND5A	2.03e-04	194	123	5	69cf7c989ac355c459db13f9d4267b55adc3c174
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 MKI67 ATP13A3 CKAP2 PLK4	2.03e-04	194	123	5	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.03e-04	194	123	5	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KIF23 RTTN CEP95 PLK4 PLCE1	2.03e-04	194	123	5	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RFX7 LDHB WDFY4 POLR3E CKAP2	2.07e-04	195	123	5	a4d36654b968acb1aea252ac203683939461f1d1
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RFX7 LDHB WDFY4 POLR3E CKAP2	2.07e-04	195	123	5	cd811abd949ef201aef1c8515da5575ab1b1cfea
ToppCell	CF-Myeloid\|CF / Disease state, Lineage and Cell class	CPD ZEB2 ATP13A3 DENND5A IL6R	2.07e-04	195	123	5	ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF23 MKI67 CKAP2 CDC25A PLK4	2.07e-04	195	123	5	75759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	6d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	KIF23 KIF26B MKI67 CKAP2 PLK4	2.12e-04	196	123	5	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	3dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	4f649e3bfd21f21682678828673843a7d51c4ff2
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LRGUK NANOS1 MAP3K19 IMPG2 PLCE1	2.12e-04	196	123	5	7e98380d815fbf6254289ace2af37aac6fef51e8
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF23 TMTC1 MKI67 CKAP2 PLK4	2.12e-04	196	123	5	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIF23 KIF26B MKI67 CKAP2 PLK4	2.12e-04	196	123	5	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.12e-04	196	123	5	0c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCell	Control-Myeloid-proliferating_Myeloid_cells\|Control / Disease group,lineage and cell class （2021.01.30）	KIF23 MKI67 CKAP2 CDC25A PLK4	2.18e-04	197	123	5	ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF23 TMTC1 MKI67 CKAP2 PLK4	2.18e-04	197	123	5	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCF2L2 WDFY4 MKI67 BRINP2 CKAP2	2.18e-04	197	123	5	d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF23 MKI67 CKAP2 DSEL CDC25A	2.18e-04	197	123	5	196eaecef7003ed83f323c1f157c6a3594650097
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	TMEM63B FBN2 IFT80 DSEL PLCE1	2.23e-04	198	123	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	(3)_DC_Monocyte_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.23e-04	198	123	5	e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD8+_T_naive\|Int-URO / Disease, condition lineage and cell class	USP45 LDHB ABCB1 DSEL PLK4	2.23e-04	198	123	5	8c7d00d8c27fb47954d8ac53eebc4582e92b970c
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.23e-04	198	123	5	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	proximal-Epithelial-Proliferating_Basal\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.28e-04	199	123	5	521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AMPD1 KIF23 MKI67 CKAP2 PLK4	2.28e-04	199	123	5	c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell	proximal-Epithelial-Proliferating_Basal-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.28e-04	199	123	5	e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.28e-04	199	123	5	88d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCell	proximal-3-Epithelial-Proliferating_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.28e-04	199	123	5	2263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCell	Mild/Remission-Developping_Plasmablast\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	KIF23 MKI67 CDC25A PLK4 IL6R	2.28e-04	199	123	5	58c772ec763109a4009f52424fbb214fc23d0c09
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF23 MKI67 CKAP2 CDC25A PLK4	2.28e-04	199	123	5	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIF23 ST6GALNAC2 MKI67 CKAP2 FAM83A	2.28e-04	199	123	5	fe22833e69928a1478df265e1c356c463611dedd
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF23 MKI67 CKAP2 CDC25A PLK4	2.28e-04	199	123	5	616c04b0605907fb218263f2164c36cb2fa26b87
Drug	Somnium	NF1 AASS GRHL3	1.46e-07	3	121	3	CID003082954
Drug	Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	TAF1A HECTD4 TSFM BAZ1A MSL3 PLPBP PLK4 USP6NL	1.03e-05	196	121	8	5317_DN
Drug	Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	RNGTT WDR7 CPD AHCYL2 DLG3 MCF2L CDC25A AP3D1	1.03e-05	196	121	8	6236_DN
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	RNGTT NCKIPSD TSFM NF1 NDUFAF7 PLPBP MCF2L CDC25A	1.10e-05	198	121	8	1655_DN
Disease	Colorectal Carcinoma	AMPD1 MCF2L2 ZEB2 ABCB1 DACT1 FBN2 NF1 MKI67 TENM1 DLG3 C2CD6 DSEL	2.35e-05	702	117	12	C0009402
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5C KDM5D	9.30e-05	4	117	2	DOID:0060809 (implicated_via_orthology)
Disease	coronary artery disease	KCNH7 RPS6KA1 HECTD4 ZEB2 GLMN FBN2 TTC29 DENND5A MCF2L CDC25A PRDM16 TNXB IL6R PLCE1	2.77e-04	1194	117	14	EFO_0001645
Disease	COVID-19, coronary artery disease	TAF1A IL6R	1.18e-03	13	117	2	EFO_0001645, MONDO_0100096
Disease	neuronal ceroid lipofuscinosis (implicated_via_orthology)	DNAJC5G ATP13A3	1.38e-03	14	117	2	DOID:14503 (implicated_via_orthology)
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	HECTD4 MCF2L IL6R	1.45e-03	56	117	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	mean corpuscular hemoglobin concentration	SETD1B RPS6KA1 RTTN HECTD4 ZEB2 BAZ1A BYSL FAM47E PRDM16 PLK4 IL6R IMPG2	1.48e-03	1105	117	12	EFO_0004528
Disease	fibrinogen measurement, factor VII measurement	HECTD4 MCF2L IL6R	1.60e-03	58	117	3	EFO_0004619, EFO_0004623
Disease	colon cancer (is_marker_for)	KDM5C NF1 PLK4	1.68e-03	59	117	3	DOID:219 (is_marker_for)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5C KDM5D	1.80e-03	16	117	2	DOID:0050888 (implicated_via_orthology)
Disease	mean platelet volume	SETD1B RTTN SSH1 KIF28P DLG3 ATP13A3 HADHB MCF2L PRDM16 IL6R PLCE1	2.47e-03	1020	117	11	EFO_0004584
Disease	Benign Neoplasm	NAT1 ABCB1 DNAJC10	2.52e-03	68	117	3	C0086692
Disease	Neoplasms	NAT1 ABCB1 DNAJC10	2.52e-03	68	117	3	C0027651
Disease	myocardial infarction	NCKIPSD HECTD4 ZEB2 PRDM16 AP3D1 IL6R	2.77e-03	350	117	6	EFO_0000612
Disease	Neutropenia	ABCB1 AP3D1	3.12e-03	21	117	2	C0027947
Disease	Primary microcephaly	RTTN PLK4	3.42e-03	22	117	2	C0431350

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPAKKYSTGMIHLLL	NAT1	96	P18440
MDLGAITKYSALHAK	PGM3	1	O95394
MKVLGSKHLDLLYPT	ADH6	51	P28332
LEKILQAMGKSYHPG	AJUBA	411	Q96IF1
SAGLTKGMHAYRKLL	ATP13A3	176	Q9H7F0
DALSKHLVMKLSYGP	AASS	816	Q9UDR5
SLLHQLDPYMKKLAA	ACAP3	206	Q96P50
AKLKMHPYDLTVDSL	AMPD1	346	P23109
YQSKEGKSPLHMAAI	ANKRD52	301	Q8NB46
ISKAMLPNYDHVTGK	CLIP4	261	Q8N3C7
LSGTSYKDLMPHDLA	HADHB	66	P55084
YDLTPGEKMKILHAL	BAZ1A	606	Q9NRL2
LGFMALYSLLPHKEL	ALG12	296	Q9BV10
YLGLLAMSKILKTHP	AP3D1	321	O14617
SQILKKMDPVHYPSL	AOX1	531	Q06278
SKLPDMLKDHYPCVS	CKAP2	636	Q8WWK9
EMKPHSYLDAIRSGL	MKRN2	141	Q9H000
PMEAYALKAKSHVLI	NPFFR2	461	Q9Y5X5
MLLSHKLELTAKQYP	RIC1	286	Q4ADV7
MAEKPKLHYSNARGS	GSTA5	1	Q7RTV2
PEEMKYLTSLKNLHL	LRRC69	76	Q6ZNQ3
PDYAKAKISAAHIIM	ABCB1	996	P08183
VHLYELLKKMTGKPE	NT5DC1	291	Q5TFE4
HPSMLSNYLKSLKVK	RNGTT	46	O60942
HLSPKADVKNLMSYV	LETMD1	46	Q6P1Q0
MVHLYAKPGKSNADV	KCNH7	811	Q9NS40
HLKKPLEDYMALFPS	GALNT10	191	Q86SR1
GSKHIPYKESKLAML	KIF26B	746	Q2KJY2
YTLDELPTMLHKLKI	KDM5D	741	Q9BY66
YLESILMPKLEHKDS	C2CD6	346	Q53TS8
HMEKYLSFPTLKASL	C9orf131	1041	Q5VYM1
QGLSPHYSFKKTMKL	MCF2L2	891	Q86YR7
MQSPSLHKLVLGKYG	TSFM	221	P43897
KEAMALYTTHILKGP	NANOS1	221	Q8WY41
MSYAFLLALLKKHSG	OR4M1	216	Q8NGD0
DTSASMPKLFLHLEK	MSL3	376	Q8N5Y2
FRHLYASSKPVMGLK	FAM83A	286	Q86UY5
LKPEAHPTKYISSNM	LRGUK	621	Q96M69
LAFRKLTPSAGKAMH	MKI67	1891	P46013
PMYTHSIAALLKEAK	HECTD4	3541	Q9Y4D8
HEGKPLKLMVYNSKS	GORASP1	156	Q9BQQ3
KGDPHEMKITSAYLQ	NDUFA10	221	O95299
PRSVKMHIKYDLKGS	PIPSL	196	A2A3N6
FASLIYLKPKGLHSM	OR10H3	256	O60404
YLKPKGLHSMYSDAL	OR10H3	261	O60404
YLKPKGLHSMYSDAL	OR10H4	261	Q8NGA5
MSLYAVLDLKKGASP	DNAJC5G	16	Q8N7S2
PSKESKMAHILLFSG	IFT80	656	Q9P2H3
ALKEGKTSMHPPYSL	IL6R	396	P08887
IHIKSGESPMAYLNK	GRHL3	241	Q8TE85
HPSSSKKMDGYILSL	DACT1	331	Q9NYF0
HPVMSGAEAKLTYQK	DNAH17	611	Q9UFH2
EYTGPTKMHKLLHIL	AXDND1	241	Q5T1B0
AYLPAKLDKKIHSGA	TMEM63B	666	Q5T3F8
LAKAYASNHPIMKTG	CPD	291	O75976
KSHEDMLYPPSVLSK	CEP95	216	Q96GE4
YLKVAKPGSLHLNDM	DLG3	306	Q92796
YHILIVPSKKLGGSM	DENND5A	956	Q6IQ26
KATRTLHLGKMPYLS	IL12RB1	296	P42701
MLSSVPDLHGYIDKS	MCF2L	196	O15068
FRYLMAEKLGIHPSS	LDHB	171	P07195
QDSMLPLGSYHKTIK	CCDC168	3471	Q8NDH2
HKTIKYASLLFPKGM	CCDC168	3481	Q8NDH2
MAPVKYHGDRSKESL	DNAJC10	211	Q8IXB1
NGLSYLHTAKKKLMP	FBN2	2851	P35556
LHTAKKKLMPGTYTL	FBN2	2856	P35556
LSSGTEKKPHYMEVL	POLR2M	221	P0CAP2
LFHMLLNYKKKPTTG	DIRAS3	191	O95661
ILHLAKSSYLAPFMK	DNAH2	306	Q9P225
SMTYDDIPHLSAKIK	POLR3E	36	Q9NVU0
LKKSMLHPSLYFDAG	DSEL	56	Q8IZU8
HLYMALKKALFKPGA	BYSL	271	Q13895
AAMGKKVLHIPYRDS	KIF28P	296	B7ZC32
SHMKYSGRSIKFLLP	MAP3K19	196	Q56UN5
GRASKGNKLHYPIME	DRP2	641	Q13474
AGKHQDLKYISPEIM	CDC25A	351	P30304
GTNKMVPYRDSKLTH	KIF23	381	Q02241
KKVSLVMLGPAYNHT	OR52I2	21	Q8NH67
AMEALSHLSKLKPFY	MROH2A	876	A6NES4
LKPLHIGLNMSKAHY	GLMN	506	Q92990
SRHKYKMLADLTPGV	C8orf17	46	Q9NRJ1
DKKASVLYIEGHMNP	PWWP3A	436	Q2TAK8
TEMSKYKHKSSPLLP	RTTN	2106	Q86VV8
YETKPSHDALHTMKL	FAM47E	241	Q6ZV65
AQGKVHSLMEKDSYP	RGS8	146	P57771
PKKMDEYVASLHLPT	AHCYL2	566	Q96HN2
LEGSLAMDLKYHAGK	FER1L5	1021	A0AVI2
KKSHGLATVRMLPTY	HKDC1	501	Q2TB90
HLMYKIKSTGPITVA	NDUFAF7	46	Q7L592
PKHTAKMLFSGLLEL	PLCE1	991	Q9P212
IGIGTSLMNDYPKHK	SEC11B	136	P0C7V7
KLGSEILFYHPKSNM	TAF1A	101	Q15573
MQEKKLGSLPYHSAF	PRDM16	711	Q9HAZ2
KMKPLIFYANHDLSL	ST6GALNAC2	341	Q9UJ37
PLPKVKHEMDLAYTS	TENM1	11	Q9UKZ4
SYKLMIDPALKKGHH	SETD1B	31	Q9UPS6
VPSSYHLPKEMKSLK	SLF2	151	Q8IX21
GDLVSTHKLAFPSKM	IMPG2	456	Q9BZV3
SKTKPADMVIEAYGH	PLPBP	46	O94903
GLATQLKMPHEKHYT	PLK4	156	O00444
YSSAMKSKLPVLQKH	STYX	41	Q8WUJ0
SPGDKLRMEYLSLMH	NCKIPSD	651	Q9NZQ3
MDKPSLIFDHLYLGS	SSH1	306	Q8WYL5
SNKYKPGLVHVMLAL	BRINP2	556	Q9C0B6
LVVFPSHLLGKDKMS	TEX44	121	Q53QW1
PVYDITKKHLILSGM	SLC25A14	216	O95258
MAEIHTPYSSLKKLL	TSPAN16	1	Q9UKR8
KYTMEGKGRAAHPAL	USP6NL	501	Q92738
FLFLHSMKETEKGPL	USP45	256	Q70EL2
KGMAENTSHKSYRPL	TMTC1	81	Q8IUR5
MYPTLDFLKSHIKRG	SPATA46	191	Q5T0L3
HAKAGSILASYLKML	SLC5A10	296	A0PJK1
TISGLEPDHKYKMNL	TNXB	2041	P22105
VTISGLEPDHKYKMN	TNXB	2681	P22105
KLYSGMFSADPRHIL	WDFY4	1971	Q6ZS81
YLLLSMVKLIHADPK	NF1	491	P21359
LVKSHYIGTKSMAAL	RFX7	151	Q2KHR2
LGPKMLTRHYDPSKI	SLC9B1	491	Q4ZJI4
SYDTKPDSLLHLMVK	TRPM1	76	Q7Z4N2
KKMLTLPHGADEVYI	ZNF644	1246	Q9H582
PSYKGLMRLLHCKTL	UBR3	911	Q6ZT12
PLMDETKVHYGIAKA	TTC29	391	Q8NA56
KEGPSSLFIHMKSIL	TMEM72	176	A0PK05
TSPINPYKDHMSVLK	ZEB2	646	O60315
YSDKIKQMLVPHGLL	PPP1R10	606	Q96QC0
SDKGNLPKYSHNSLM	WDR7	661	Q9Y4E6
YTLDELPAMLHKLKV	KDM5C	751	P41229
KVTRPDSGHLYAMKV	RPS6KA1	81	Q15418