Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

SI MGAM

4.73e-055442GO:0004558
GeneOntologyMolecularFunctionalpha-glucosidase activity

SI MGAM

9.90e-057442GO:0090599
GeneOntologyMolecularFunctionglucosidase activity

SI MGAM

4.89e-0415442GO:0015926
GeneOntologyMolecularFunctionplatelet-derived growth factor receptor binding

PDGFRA ITGB3

6.32e-0417442GO:0005161
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

SI MGAM MAN1C1

1.51e-03103443GO:0004553
GeneOntologyBiologicalProcessextracellular matrix organization

LAMB1 CCDC80 TFIP11 SH3PXD2B PDGFRA ITGB3 ADAMTSL2

1.38e-05377447GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

LAMB1 CCDC80 TFIP11 SH3PXD2B PDGFRA ITGB3 ADAMTSL2

1.40e-05378447GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

LAMB1 CCDC80 TFIP11 SH3PXD2B PDGFRA ITGB3 ADAMTSL2

1.43e-05379447GO:0045229
GeneOntologyBiologicalProcessdisaccharide catabolic process

SI MGAM

2.66e-054442GO:0046352
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A3 CSNK2A1

2.59e-054442GO:0005956
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMB1 ITGB3 ITGB6

2.60e-0459443GO:0098636
GeneOntologyCellularComponentdendritic growth cone

CYFIP1 PTCH1

2.82e-0412442GO:0044294
GeneOntologyCellularComponentdendrite terminus

CYFIP1 PTCH1

8.03e-0420442GO:0044292
DomainGlyco_hydro_31_CS

SI MGAM

3.24e-054442IPR030459
DomainNtCtMGAM_N

SI MGAM

3.24e-054442PF16863
DomainGal_mutarotase_N

SI MGAM

3.24e-054442IPR031727
Domain-

ITGB3 ITGB6

3.24e-0544421.20.5.630
DomainGLYCOSYL_HYDROL_F31_2

SI MGAM

5.40e-055442PS00707
DomainGlyco_hydro_31_AS

SI MGAM

8.09e-056442IPR030458
DomainIntegrin_bsu_cyt_dom

ITGB3 ITGB6

8.09e-056442IPR014836
DomainIntegrin_b_cyt

ITGB3 ITGB6

8.09e-056442SM01241
DomainIntegrin_b_cyt

ITGB3 ITGB6

8.09e-056442PF08725
DomainGlyco_hydro_31

SI MGAM

1.13e-047442PF01055
DomainGlyco_hydro_31

SI MGAM

1.13e-047442IPR000322
DomainIntegrin_bsu_tail

ITGB3 ITGB6

1.13e-047442IPR012896
DomainGLYCOSYL_HYDROL_F31_1

SI MGAM

1.13e-047442PS00129
DomainIntegrin_B_tail

ITGB3 ITGB6

1.13e-047442SM01242
DomainIntegrin_B_tail

ITGB3 ITGB6

1.13e-047442PF07965
DomainTrefoil

SI MGAM

1.51e-048442PF00088
DomainINB

ITGB3 ITGB6

1.51e-048442SM00187
DomainP_TREFOIL_1

SI MGAM

1.51e-048442PS00025
DomainIntegrin_beta

ITGB3 ITGB6

1.51e-048442PF00362
DomainIntegrin_bsu_VWA

ITGB3 ITGB6

1.51e-048442IPR002369
DomainP_trefoil_CS

SI MGAM

1.51e-048442IPR017957
DomainIntegrin_bsu

ITGB3 ITGB6

1.93e-049442IPR015812
DomainP_TREFOIL_2

SI MGAM

1.93e-049442PS51448
DomainINTEGRIN_BETA

ITGB3 ITGB6

1.93e-049442PS00243
DomainPSI_integrin

ITGB3 ITGB6

1.93e-049442PF17205
DomainIntegin_beta_N

ITGB3 ITGB6

1.93e-049442IPR033760
DomainPD

SI MGAM

1.93e-049442SM00018
DomainGlycoside_hydrolase_SF

SI MGAM SLC3A1

2.63e-0453443IPR017853
Domain-

SI MGAM

2.94e-04114424.10.110.10
DomainP_trefoil_dom

SI MGAM

3.53e-0412442IPR000519
DomainGal_mutarotase_SF_dom

SI MGAM

7.21e-0417442IPR011013
DomainIntegrin_dom

ITGB3 ITGB6

1.57e-0325442IPR032695
DomainCRAL-TRIO_dom

PLEKHG4 SEC14L1

1.97e-0328442IPR001251
DomainPSI

ITGB3 ITGB6

4.82e-0344442IPR016201
DomainPSI

ITGB3 ITGB6

5.26e-0346442SM00423
DomainEGF_extracell

ITGB3 ITGB6

8.80e-0360442IPR013111
DomainEGF_2

ITGB3 ITGB6

8.80e-0360442PF07974
Domain-

ITGB3 ITGB6

1.32e-02744423.40.50.410
PathwayREACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE

SI MGAM

1.47e-048332MM14717
PathwayREACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE

SI MGAM

2.88e-0411332M1091
PathwayKEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT

CSNK2A3 CSNK2A1

4.08e-0413332M47763
PathwayWP_OSTEOBLAST_SIGNALING

PDGFRA ITGB3

4.75e-0414332M39599
PathwayWP_PLEURAL_MESOTHELIOMA

LAMB1 PDGFRA CSNK2A3 ITGB3 CSNK2A1 MCU

4.78e-04439336M42563
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMB1 ITGB3 ITGB6

7.31e-0476333M27219
PathwayREACTOME_SIGNAL_TRANSDUCTION_BY_L1

ITGB3 CSNK2A1

8.86e-0419332MM15113
PathwayWP_FOCAL_ADHESION

LAMB1 PDGFRA ITGB3 ITGB6

9.08e-04187334MM15913
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB1 ITGB3 ITGB6

9.79e-0484333M7098
PathwayBIOCARTA_EDG1_PATHWAY

PDGFRA ITGB3

9.83e-0420332MM1456
PathwayWP_PI3KAKT_SIGNALING

LAMB1 PIK3R6 PDGFRA ITGB3 ITGB6

1.07e-03339335M39736
PathwayREACTOME_SIGNAL_TRANSDUCTION_BY_L1

ITGB3 CSNK2A1

1.09e-0321332M878
PathwayREACTOME_DIGESTION

SI MGAM

1.09e-0321332MM15526
PathwayWP_FOCAL_ADHESION

LAMB1 PDGFRA ITGB3 ITGB6

1.14e-03199334M39402
PathwayKEGG_FOCAL_ADHESION

LAMB1 PDGFRA ITGB3 ITGB6

1.14e-03199334M7253
PathwayPID_PDGFRA_PATHWAY

PDGFRA CSNK2A1

1.19e-0322332M206
PathwayBIOCARTA_EDG1_PATHWAY

PDGFRA ITGB3

1.19e-0322332M10579
PathwayREACTOME_DIGESTION

SI MGAM

1.30e-0323332M27790
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY

ITGB3 ITGB6

1.30e-0323332M47537
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY

ITGB3 ITGB6

1.30e-0323332M47720
PathwayKEGG_REGULATION_OF_ACTIN_CYTOSKELETON

CYFIP1 PDGFRA ITGB3 ITGB6

1.47e-03213334M18306
PathwayREACTOME_DIGESTION_AND_ABSORPTION

SI MGAM

1.54e-0325332MM15557
PathwayPID_INTEGRIN_CS_PATHWAY

ITGB3 ITGB6

1.67e-0326332M47
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY

ITGB3 ITGB6

1.67e-0326332M47719
PathwayREACTOME_SULFUR_AMINO_ACID_METABOLISM

APIP CSAD

1.93e-0328332M547
PathwayREACTOME_DIGESTION_AND_ABSORPTION

SI MGAM

1.93e-0328332M27837
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY

ITGB3 ITGB6

1.93e-0328332M47655
PathwayBIOCARTA_PDGF_PATHWAY

PDGFRA CSNK2A1

1.93e-0328332M2529
PathwayBIOCARTA_PDGF_PATHWAY

PDGFRA CSNK2A1

2.07e-0329332MM1452
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY

ITGB3 ITGB6

2.22e-0330332M47724
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY

ITGB3 ITGB6

2.22e-0330332M47718
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

ITGB3 ITGB6

2.52e-0332332MM14854
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_STAGE_2_OF_3

PTCH1 PDGFRA

2.52e-0332332M40041
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

PDGFRA ITGB3 ITGB6

2.79e-03121333M39823
PathwayREACTOME_L1CAM_INTERACTIONS

LAMB1 ITGB3 CSNK2A1

2.79e-03121333M872
Pubmed

Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist.

ITGB3 ITGB6

1.56e-06244236669646
Pubmed

Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion.

SI MGAM

1.56e-06244236968271
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A3 CSNK2A1

1.56e-06244214646071
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A3 CSNK2A1

1.56e-0624421577469
Pubmed

Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.

SI MGAM

1.56e-06244227480812
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A3 CSNK2A1

1.56e-06244212860116
Pubmed

Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.

SI MGAM

1.56e-06244220356844
Pubmed

Molecular cloning of the human casein kinase II alpha subunit.

CSNK2A3 CSNK2A1

1.56e-0624422752008
Pubmed

Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.

CSNK2A3 CSNK2A1

1.56e-0624428420794
Pubmed

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

CSNK2A3 CSNK2A1

4.69e-06344215684395
Pubmed

The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.

LAMB1 PDGFRA

4.69e-06344228783171
Pubmed

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

CSNK2A3 CSNK2A1

4.69e-0634422174700
Pubmed

Partial characterization of murine intestinal maltase-glucoamylase.

SI MGAM

4.69e-06344212150962
Pubmed

Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.

CSNK2A3 CSNK2A1

4.69e-0634421766873
Pubmed

Hedgehog signaling via its ligand DHH acts as cell fate determinant during skeletal muscle regeneration.

PTCH1 PDGFRA

4.69e-06344237355632
Pubmed

Crystallization and preliminary characterization of crystals of human protein kinase CK2.

CSNK2A3 CSNK2A1

4.69e-06344211092945
Pubmed

Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.

CSNK2A3 CSNK2A1

4.69e-06344212102635
Pubmed

The oligodendrocyte precursor mitogen PDGF stimulates proliferation by activation of alpha(v)beta3 integrins.

PDGFRA ITGB3

4.69e-06344211953315
Pubmed

Interaction of alphaVbeta3 and alphaVbeta6 integrins with human parechovirus 1.

ITGB3 ITGB6

4.69e-06344220554778
Pubmed

Integrin expression and glycosylation patterns regulate cell-matrix adhesion and alter with breast cancer progression.

ITGB3 ITGB6

4.69e-06344229577899
Pubmed

Patterns and rates of exonic de novo mutations in autism spectrum disorders.

KATNAL2 ZNF292

4.69e-06344222495311
Pubmed

Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.

CSNK2A3 CSNK2A1

4.69e-06344220625391
Pubmed

The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1.

ITGB3 ITGB6

4.69e-0634421382574
Pubmed

αvβ3, αvβ5 and αvβ6 integrins in brain metastases of lung cancer.

ITGB3 ITGB6

9.37e-06444225150423
Pubmed

Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases.

KATNAL2 ZNF292

1.56e-05544228191889
Pubmed

Hedgehog-responsive mesenchymal clusters direct patterning and emergence of intestinal villi.

PTCH1 PDGFRA

1.56e-05544223019366
Pubmed

YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.

PTCH1 PDGFRA ITGB6

1.81e-054044328323616
Pubmed

Genetic loci associated with circulating levels of very long-chain saturated fatty acids.

DOCK7 ITGB3 SEC14L1

2.10e-054244325378659
Pubmed

alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity.

ITGB3 ITGB6

2.34e-05644217158881
Pubmed

Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression.

LAMB1 ITGB3

2.34e-05644218162078
Pubmed

A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve.

PTCH1 PDGFRA

2.34e-05644210357934
Pubmed

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.

ITGB3 ITGB6

2.34e-05644224216753
Pubmed

Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development.

ITGB3 ITGB6

2.34e-0564428601592
Pubmed

Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains.

ITGB3 ITGB6

3.27e-0574428798654
Pubmed

Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle.

PTCH1 PDGFRA

3.27e-05744210331973
Pubmed

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.

CSNK2A3 CSNK2A1

3.27e-05744211239457
Pubmed

Cellular taxonomy of Hic1+ mesenchymal progenitor derivatives in the limb: from embryo to adult.

PTCH1 PDGFRA

3.27e-05744236008423
Pubmed

The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens.

LAMB1 PDGFRA

3.27e-05744215183724
Pubmed

Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin.

ITGB3 ITGB6

4.36e-05844216005200
Pubmed

Gli1 is not required for Pdgfralpha expression during mouse embryonic development.

PTCH1 PDGFRA

4.36e-05844215811134
Pubmed

Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

ITGB3 ITGB6

4.36e-0584429553049
Pubmed

Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad.

PTCH1 PDGFRA

4.36e-05844212651897
Pubmed

p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.

CSNK2A3 CSNK2A1

4.36e-05844212393879
Pubmed

Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype.

PTCH1 PDGFRA

5.60e-05944229999500
Pubmed

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.

PTCH1 PDGFRA

5.60e-05944211748155
Pubmed

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

ITGB3 ITGB6

5.60e-05944211807098
Pubmed

Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon.

PDGFRA CSNK2A1

6.99e-051044220368359
Pubmed

Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein.

PDGFRA ITGB3

6.99e-051044222027834
Pubmed

Analysis of Nsdhl-deficient embryos reveals a role for Hedgehog signaling in early placental development.

PTCH1 PDGFRA

8.54e-051144217028112
Pubmed

Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain.

PTCH1 PDGFRA

8.54e-051144221451043
Pubmed

Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon.

ENPP6 PDGFRA

8.54e-051144234222248
Pubmed

Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.

LAMB1 SVOPL SLC3A1

9.34e-056944321491542
Pubmed

Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.

PTCH1 PDGFRA

1.02e-041244228490013
Pubmed

Integrins.

ITGB3 ITGB6

1.02e-041244219693543
Pubmed

Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development.

PTCH1 PDGFRA

1.02e-041244212756179
Pubmed

Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer.

CSNK2A1 ARCN1

1.02e-041244236793866
Pubmed

Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.

PTCH1 PDGFRA

1.21e-041344218625210
Pubmed

Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.

LAMB1 PDGFRA

1.41e-041444218559345
Pubmed

Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis.

PTCH1 PDGFRA

1.63e-041544230595533
Pubmed

Radial construction of an arterial wall.

PTCH1 PDGFRA

1.63e-041544222975322
Pubmed

Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation.

PTCH1 PDGFRA

1.63e-041544223178882
Pubmed

Integrin requirement for hippocampal synaptic plasticity and spatial memory.

ITGB3 ITGB6

1.86e-041644212904471
Pubmed

Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets.

PTCH1 PDGFRA

1.86e-041644226457609
Pubmed

Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.

LAMB1 PDGFRA

1.86e-041644235132078
Pubmed

Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells.

PTCH1 PDGFRA

1.86e-041644223840809
Pubmed

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.

PTCH1 PDGFRA

2.10e-041744232155439
Pubmed

Stage-specific regulation of oligodendrocyte development by Wnt/β-catenin signaling.

PTCH1 PDGFRA

2.10e-041744224948802
Pubmed

Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain.

PTCH1 PDGFRA

2.10e-041744217678855
Pubmed

Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.

LAMB1 ITGB3

2.10e-041744218082680
Pubmed

Keratan Sulfate Regulates the Switch from Motor Neuron to Oligodendrocyte Generation During Development of the Mouse Spinal Cord.

PTCH1 PDGFRA

2.36e-041844226869039
Pubmed

Villification in the mouse: Bmp signals control intestinal villus patterning.

PTCH1 PDGFRA

2.36e-041844226721501
Pubmed

Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling.

PTCH1 PDGFRA

2.36e-041844219141668
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

DOCK7 PDGFRA ITGB3

2.41e-049544324029230
Pubmed

Unravelling the complex genetics of cleft lip in the mouse model.

PTCH1 ITGB3

2.64e-041944211353389
Pubmed

The ciliary protein Ftm is required for ventricular wall and septal development.

PTCH1 PDGFRA

2.64e-041944223469020
Pubmed

Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.

PTCH1 PDGFRA

2.64e-041944224886827
Pubmed

Notch signaling maintains Leydig progenitor cells in the mouse testis.

PTCH1 PDGFRA

3.24e-042144218927153
Pubmed

Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling.

PTCH1 PDGFRA

3.56e-042244224000064
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DOCK7 ENPP6 CYFIP1 VIRMA DAGLA CSNK2A1 ARCN1 MCU

3.81e-04143144837142655
Pubmed

Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.

PTCH1 PDGFRA

3.89e-042344228036337
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

PDGFRA ITGB6

3.89e-042344219897741
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ITGB3 ITGB6

3.89e-042344223152823
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TFIP11 CYFIP1 CSNK2A3 CSNK2A1 ZNF292

4.01e-0449744536774506
Pubmed

Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization.

PTCH1 PDGFRA

4.24e-042444212403705
Pubmed

GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.

PTCH1 PDGFRA

4.24e-042444232497091
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

IPO13 LAMB1 CSNK2A1 SLC3A1

4.57e-0428444429459677
Pubmed

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.

PTCH1 PDGFRA

4.61e-042544230541888
Pubmed

Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.

PTCH1 PDGFRA

5.38e-042744225631042
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGB3 ITGB6

5.38e-042744231541017
Pubmed

An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.

PTCH1 PDGFRA

5.79e-042844235112129
Pubmed

Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.

PTCH1 PDGFRA

6.21e-042944222898775
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

DOCK7 TFIP11 SH3PXD2B CYFIP1 ARCN1

6.29e-0454944538280479
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

PTCH1 ITGB3

6.65e-043044232882513
Pubmed

Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord.

PTCH1 PDGFRA

6.65e-043044223482494
Pubmed

FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme.

PTCH1 PDGFRA

7.11e-043144230153454
Pubmed

Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype.

PTCH1 PDGFRA

7.11e-043144223023706
Pubmed

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate.

PTCH1 PDGFRA

7.11e-043144236362374
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

LAMB1 ITGB3

7.57e-043244223154389
Pubmed

Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome.

PTCH1 PDGFRA

7.57e-043244236920550
Pubmed

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.

LAMB1 CYFIP1 ARCN1

7.65e-0414144332322062
InteractionF2RL3 interactions

CSNK2A3 VIRMA CSNK2A1

7.53e-079433int:F2RL3
InteractionANKRD36C interactions

CSNK2A3 VIRMA CSNK2A1

1.96e-0612433int:ANKRD36C
InteractionCHST3 interactions

PTCH1 PDGFRA VIRMA

4.04e-0615433int:CHST3
InteractionITGAV interactions

PTCH1 PDGFRA VIRMA ITGB3 ITGB6

2.44e-05163435int:ITGAV
InteractionANKRD36 interactions

CSNK2A3 VIRMA CSNK2A1

4.30e-0532433int:ANKRD36
InteractionSNRK interactions

VIRMA CSNK2A1 ARCN1

5.65e-0535433int:SNRK
InteractionCPEB2 interactions

TFIP11 USP42 VIRMA

6.15e-0536433int:CPEB2
InteractionWASHC4 interactions

DOCK7 LAMB1 VIRMA CSNK2A1

6.56e-05102434int:WASHC4
GeneFamilyCD molecules|Integrin beta subunits

ITGB3 ITGB6

5.06e-0592221159
CoexpressionGSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_UP

DOCK7 PTCH1 SLC3A1 ZNF292 SEC14L1

2.10e-05200445M5838
CoexpressionPICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP

LAMB1 CCDC80 CCL14 CYFIP1 PDGFRA

2.71e-05211445M12225
CoexpressionGALIE_TUMOR_STEMNESS_GENES

PTCH1 PDGFRA

4.11e-056442M1295
CoexpressionGALIE_TUMOR_STEMNESS_GENES

PTCH1 PDGFRA

4.11e-056442MM546
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

LAMB1 CCDC80 C3orf80 SH3PXD2B PDGFRA

8.78e-07178445142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP6 LAMB1 CLSTN2 PTCH1 PDGFRA

1.15e-06188445997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

LAMB1 CCDC80 SH3PXD2B CLSTN2 LRFN5

1.27e-06192445356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

LAMB1 CCDC80 SH3PXD2B PDGFRA LRFN5

1.34e-0619444503a269f75a481ea54aea8e6444605db8d6df493d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 PTCH1 PDGFRA LRFN5 ADAMTSL2

1.34e-06194445e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP6 LAMB1 CLSTN2 PTCH1 PDGFRA

1.45e-06197445ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCellfacs-Heart|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 LAMB1 CCDC80 PDGFRA ADAMTSL2

1.45e-061974456a9571c0a3238b39214afdece93d7541bc8a0a70
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP6 LAMB1 CCDC80 PTCH1 PDGFRA

1.45e-06197445eb07545bef5ad506fbbe3a1f99131f26c1447a31
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

LAMB1 CCDC80 SH3PXD2B PDGFRA LRFN5

1.48e-061984453ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 SAT2 PDGFRA

1.52e-0619944538ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 PTCH1 PDGFRA

1.52e-06199445a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 SAT2 PDGFRA

1.52e-061994451a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 SAT2 PDGFRA

1.52e-06199445211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 PTCH1 PDGFRA

1.56e-062004459b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 SAT2 PDGFRA

1.56e-06200445ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 CCDC80 SH3PXD2B CLSTN2 LRFN5

1.56e-06200445ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 PTCH1 SAT2

1.56e-0620044564ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 PTCH1 PDGFRA

1.56e-06200445a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 PTCH1 SAT2

1.56e-06200445a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

LAMB1 CCDC80 PTCH1 SAT2 PDGFRA

1.56e-06200445a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 PTCH1 PDGFRA LRFN5 ADAMTSL2

1.56e-06200445fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 CCDC80 CLSTN2 PDGFRA LRFN5

1.56e-062004450c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP6 CLSTN2 PTCH1 PDGFRA

1.87e-051604446215ac6123a295f3c2f033786602a57b2e2e1177
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 CCDC80 CLSTN2 DAGLA

2.21e-05167444b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 PDGFRA LRFN5

2.78e-05177444bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 CLSTN2 PTCH1 PDGFRA

3.03e-05181444b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMB1 PTCH1 PDGFRA ADAMTSL2

3.03e-05181444d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CCDC80 CLSTN2 PDGFRA LRFN5

3.23e-0518444467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

CCDC80 CLSTN2 LRFN5 ADAMTSL2

3.23e-051844442b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC80 SH3PXD2B CLSTN2 ADAMTSL2

3.30e-051854449faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3orf80 CLSTN2 BAIAP3 MAN1C1

3.30e-051854442a8104f610fa5ce618f8105521616722462a0d42
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CLSTN2 PTCH1 PDGFRA

3.37e-05186444360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

LAMB1 PDGFRA LRFN5 ADAMTSL2

3.44e-05187444e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 CCDC80 SH3PXD2B PDGFRA

3.44e-051874444e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 CCDC80 SH3PXD2B PDGFRA

3.44e-05187444d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 CCDC80 SH3PXD2B PDGFRA

3.44e-05187444827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLSTN2 PTCH1 PDGFRA ADAMTSL2

3.44e-05187444c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

CCDC80 SH3PXD2B PDGFRA LRFN5

3.52e-05188444706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellP15-Mesenchymal|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.52e-05188444f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

LAMB1 PDGFRA LRFN5 ADAMTSL2

3.52e-05188444038f48e8daaeb72716e975d22a6b004a90654960
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMB1 CCDC80 CLSTN2 LRFN5

3.52e-051884440e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTCH1 PDGFRA LRFN5 ADAMTSL2

3.59e-0518944471397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTCH1 PDGFRA LRFN5 ADAMTSL2

3.59e-051894444eea4759520c312bd17a681034d8074e47093d2b
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 LAMB1 CCDC80 PDGFRA

3.59e-05189444bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 C3orf80 PDGFRA ADAMTSL2

3.59e-051894449e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 LAMB1 CCDC80 PDGFRA

3.59e-05189444cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 LAMB1 CCDC80 PDGFRA

3.59e-0518944487323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ENPP6 LAMB1 CCDC80 PTCH1

3.59e-051894442a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

LAMB1 CCDC80 PDGFRA LRFN5

3.67e-051904443a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.74e-05191444aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMB1 SH3PXD2B CLSTN2 LRFN5

3.74e-0519144470c067c54084bfb02c29bab085f4defd477194fb
ToppCell5'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 CLSTN2 PDGFRA

3.74e-05191444054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

APIP PDGFRA CSAD ADAMTSL2

3.74e-05191444e7c605b56934d1383237c1f946dbccef25d91368
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.74e-05191444997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTCH1 PDGFRA LRFN5 ADAMTSL2

3.82e-05192444bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 CLSTN2 PDGFRA

3.82e-051924449479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCellfacs-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.82e-051924448df15085b35b86f39debd933284cb703c5dd63c2
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.82e-05192444671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 CLSTN2 PDGFRA

3.82e-05192444d7faa993f68e530ad55185505384ae155d36c222
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 PDGFRA LRFN5 ADAMTSL2

3.82e-051924445105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.82e-05192444840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 MAN1C1 TMEM51 MCU

3.82e-05192444fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 MAN1C1 TMEM51 MCU

3.82e-05192444bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTCH1 PDGFRA LRFN5 ADAMTSL2

3.82e-051924440ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 PTCH1 PDGFRA

3.90e-0519344468089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.90e-05193444ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

LAMB1 CCDC80 SH3PXD2B CLSTN2

3.90e-05193444dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 C3orf80 PDGFRA ADAMTSL2

3.90e-05193444dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMB1 CCDC80 PDGFRA ADAMTSL2

3.90e-0519344430481fb01c7acf85beae10213f038da86bed6777
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 C3orf80 PDGFRA ADAMTSL2

3.90e-05193444e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ENPP6 LAMB1 CCDC80 LRFN5

3.98e-0519444460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

LAMB1 CCDC80 SH3PXD2B CLSTN2

3.98e-0519444411c79a8c56ece42713b04b321982e41e239f07a5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMB1 PTCH1 LRFN5 ADAMTSL2

3.98e-0519444435f132cc38ac133be01834ed0946188aa0757eb4
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 CCDC80 PDGFRA ADAMTSL2

3.98e-0519444448063c9fe3e12aeff0707acada1baa2f8621f093
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LAMB1 PTCH1 PDGFRA ADAMTSL2

3.98e-051944444f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ENPP6 LAMB1 CCDC80 LRFN5

3.98e-0519444489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTCH1 PDGFRA LRFN5 ADAMTSL2

3.98e-05194444ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

LAMB1 CCDC80 SH3PXD2B CLSTN2

3.98e-05194444014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTCH1 PDGFRA LRFN5 ADAMTSL2

3.98e-05194444cf0244a29934e515446ac917d3c30672b460fb04
ToppCellfacs-Heart-RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 CCDC80 PDGFRA ADAMTSL2

3.98e-05194444c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 CCDC80 PDGFRA ADAMTSL2

3.98e-051944444f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 CCDC80 PDGFRA LRFN5

4.14e-05196444614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CLSTN2 PTCH1 PDGFRA

4.14e-051964441f47916c2663bd88c1e7c19c6a7688f4c7173ad2
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMB1 CCDC80 PDGFRA LRFN5

4.14e-051964447d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

SH3PXD2B CLSTN2 LRFN5 ADAMTSL2

4.14e-05196444e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PTCH1 PDGFRA ADAMTSL2

4.22e-05197444b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB1 CCDC80 CLSTN2 PDGFRA

4.22e-0519744417344464fdcc5ba0c03959696b97c195f11e644c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 C3orf80 PDGFRA ADAMTSL2

4.22e-051974444cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCellfacs-Heart-LA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 CCDC80 PDGFRA ADAMTSL2

4.22e-051974442a91738cb6d7588869dd00deeea0cbbc2d6aa34d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP6 LAMB1 CLSTN2 PDGFRA

4.22e-051974441da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMB1 CCDC80 PTCH1 PDGFRA

4.22e-05197444c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 CLSTN2 PDGFRA

4.22e-05197444ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 PTCH1 PDGFRA ADAMTSL2

4.22e-05197444ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB1 CCDC80 CLSTN2 PDGFRA

4.22e-051974443bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC80 PTCH1 PDGFRA ADAMTSL2

4.22e-0519744437f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell5'-Adult-Appendix-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 CCDC80 CLSTN2 PDGFRA

4.22e-05197444b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB1 CCDC80 CLSTN2 PDGFRA

4.22e-051974445b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PTCH1 PDGFRA ADAMTSL2

4.22e-05197444c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ENPP6 LAMB1 CCDC80 SAT2

4.30e-051984440a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SI MGAM SAT2 SLC3A1

4.30e-051984448d629492d2199de8e036c19e9dacceb9c9e721a0
DrugAC1L53LJ

SI MGAM SLC3A1

6.72e-085443CID000197521
Drugisomaltotetraose

SI MGAM SLC3A1

2.34e-077443CID003080783
DrugFG5P

SI MGAM SLC3A1

1.10e-0611443CID000127486
DrugI0329

SI MGAM SLC3A1

8.74e-0621443CID000439668
Drugp-nitrophenyl

ENPP6 SI MGAM ESD SLC3A1

8.99e-06146445CID000007416
DrugCopper silicide

SI MGAM

1.09e-053442CID006336988
Drugphenyl -maltoside

MGAM SLC3A1

1.09e-053442CID003081956
DrugPalatinose hydrate

SI MGAM SLC3A1

1.16e-0523443CID000093971
Drugginsenoside

SI MGAM SLC3A1

1.16e-0523443CID000092797
DrugPanose B

SI MGAM SLC3A1

1.32e-0524443CID000439297
DrugLB-2

SI MGAM SLC3A1

2.13e-0528443CID000129887
DrugDBNPA

MGAM SLC3A1

2.18e-054442CID000025059
DrugAcarbose

SI MGAM

2.18e-054442DB00284
Drugnimbidiol

SI MGAM

2.18e-054442ctd:C496111
Drugisomaltoheptaose

MGAM SLC3A1

2.18e-054442CID003081403
Drugacetylthiocholine

CCDC80 PTCH1 ESD

2.38e-0529443CID000020544
DrugNsc1222

SI MGAM SLC3A1

2.64e-0530443CID000219660
Drugbeidellite

MGAM CLSTN2

5.45e-056442CID006367228
DrugAC1OCFTL

SI MGAM

5.45e-056442CID006918743
Drugmaltoheptose

SI MGAM SLC3A1

6.33e-0540443CID003037125
DrugAC1Q6RZL

SI MGAM SLC3A1

1.03e-0447443CID000001144
Drugleucrose

MGAM SLC3A1

1.30e-049442CID000165577
Diseaselevel of Phosphatidylinositol (18:0_20:3) in blood serum

DOCK7 DAGLA

1.29e-0412422OBA_2045157
Diseaselevel of Phosphatidylcholine (18:1_18:2) in blood serum

DOCK7 DAGLA

1.78e-0414422OBA_2045100
Disease1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement

DOCK7 DAGLA

1.78e-0414422EFO_0022085
Diseaseurate measurement, bone density

KATNAL2 CCL14 ITGB6 MAN1C1 CSNK2A1 ASB3

2.30e-04619426EFO_0003923, EFO_0004531
Diseaselevel of Phosphatidylcholine (15:0_18:2) in blood serum

DOCK7 DAGLA

2.98e-0418422OBA_2045065
Disease1,5 anhydroglucitol measurement

SI MGAM

7.84e-0429422EFO_0008009
DiseaseGrowth Disorders

SH3PXD2B ADAMTSL2

1.21e-0336422C0018273
DiseaseCraniofacial Abnormalities

SH3PXD2B PTCH1 PDGFRA

1.43e-03156423C0376634
DiseaseCleft palate, isolated

PTCH1 PDGFRA

1.64e-0342422C1837218
DiseaseChildhood Medulloblastoma

PTCH1 PDGFRA

1.72e-0343422C0278510
DiseaseMelanotic medulloblastoma

PTCH1 PDGFRA

1.72e-0343422C1275668
DiseaseMedullomyoblastoma

PTCH1 PDGFRA

1.72e-0343422C0205833
DiseaseDesmoplastic Medulloblastoma

PTCH1 PDGFRA

1.72e-0343422C0751291
DiseaseAdult Medulloblastoma

PTCH1 PDGFRA

1.72e-0343422C0278876
Diseasevery long-chain saturated fatty acid measurement

DOCK7 SEC14L1

1.80e-0344422EFO_0006796
DiseaseGastrointestinal Stromal Sarcoma

PTCH1 PDGFRA

2.05e-0347422C3179349
DiseaseMedulloblastoma

PTCH1 PDGFRA

2.32e-0350422C0025149
Diseaseomega-6:omega-3 polyunsaturated fatty acid ratio

DOCK7 DAGLA

2.32e-0350422EFO_0010732
DiseaseGastrointestinal Stromal Tumors

PTCH1 PDGFRA

2.32e-0350422C0238198

Protein segments in the cluster

PeptideGeneStartEntry
TNYRMYSYVTEELPQ

ESD

116

P10768
VEMLYEEALYTVLYR

BAIAP3

136

O94812
VTLYMDGATYEPYLV

CLSTN2

466

Q9H4D0
ERYPYPVRLEAMYEV

CCDC80

246

Q76M96
YNGTYDDTLVYRMIP

LRFN5

451

Q96NI6
EYIYVDPMQLPYDSR

PDGFRA

571

P16234
VDYYENRMYLTPSEK

CYFIP1

246

Q7L576
YFVMTRQEYVYPEAR

MCU

281

Q8NE86
IPYDVQYSDIDYMER

MGAM

1271

O43451
RQTEDYPVDLYYLMD

ITGB6

126

P18564
IDLETILMEYESYYF

KATNAL2

66

Q8IYT4
YRRPMDVYETGIEYI

ADAMTSL2

286

Q86TH1
YSMEYDILIRYEPQL

LAMB1

606

P07942
TYKIPRQRIMDYYET

CCL14

41

Q16627
NYLLYEDVLRMYEVP

ASB3

496

Q9Y575
QTLTDYDIRFYMYEI

CSNK2A3

126

Q8NEV1
IQITYVEPYFDTYEM

DOCK7

1911

Q96N67
YEEVKYLPTYEESMR

C3orf80

196

F5H4A9
QTLTDYDIRFYMYEI

CSNK2A1

126

P68400
YTYEIAPVFVLMEEE

CSAD

116

Q9Y600
ESYYILRPEVVESYM

MAN1C1

516

Q9NR34
LYTEPRDSMQYVLYV

DAGLA

86

Q9Y4D2
RQVEDYPVDIYYLMD

ITGB3

131

P05106
MTVYEKEAIPSRFYY

ENPP6

296

Q6UWR7
VYKYPFELIMAAYER

SEC14L1

11

Q92503
GRTIYLEDIYVMPEY

SAT2

86

Q96F10
RIYRVDISDTLMYVY

IPO13

421

O94829
TESVRYVYQPMEKLY

ARCN1

51

P48444
YGTAIIMYVEPQYES

OR2A25

251

A4D2G3
GYYRYDDMLVVPIIE

APIP

151

Q96GX9
PMTIYTEQDLYSYVI

ERVW-1

296

Q9UQF0
IVYEDPYQVSLQYME

TEX55

491

Q96M34
EYVRALEYTMENYFP

PLEKHG4

746

Q58EX7
DVITYYIRMGTQPIY

PIK3R6

521

Q5UE93
TETGYMDQIIEYLYP

PTCH1

211

Q13635
YAESIDRTVMYYGLP

SLC3A1

386

Q07837
IPYDVQYTDIDYMER

SI

1251

P14410
YIYTAEVYPTTMRAL

SVOPL

416

Q8N434
DVKYPEYLDIRPYMS

USP42

331

Q9H9J4
YTVIYPYTARDQDEM

SH3PXD2B

226

A1X283
IEPTVDAYYAVEMLY

ZNF292

396

O60281
ASRYYVPSYEEVMNT

TMEM51

126

Q9NW97
MTYDPYDRELVPLLY

VIRMA

336

Q69YN4
YYEEYRMSDRVDLAV

TFIP11

411

Q9UBB9