Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TUT4 STK17B CAMK2A SPEG POLR2B TUT7 COQ8B TSSK2 DGKH PFKL PFKP POLA2 TEK TESK1 CDK10 FAM20C MAST4 COQ8A GYS1 GUCY2D IRAK4 CCL3 TNKS ATM PAN3 TNKS2 RPS6KL1	1.81e-07	938	186	27	GO:0016772
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	STK17B CAMK2A SPEG COQ8B TSSK2 DGKH PFKL PFKP TEK TESK1 CDK10 FAM20C MAST4 COQ8A GUCY2D IRAK4 CCL3 ATM PAN3 RPS6KL1	1.08e-05	709	186	20	GO:0016773
GeneOntologyMolecularFunction	kinase activity	STK17B CAMK2A SPEG COQ8B TSSK2 DGKH PFKL PFKP TEK TESK1 CDK10 FAM20C MAST4 COQ8A GUCY2D IRAK4 CCL3 ATM PAN3 RPS6KL1	3.15e-05	764	186	20	GO:0016301
GeneOntologyMolecularFunction	protein kinase activity	STK17B CAMK2A SPEG COQ8B TSSK2 TEK TESK1 CDK10 FAM20C MAST4 COQ8A GUCY2D IRAK4 CCL3 ATM PAN3 RPS6KL1	4.85e-05	600	186	17	GO:0004672
GeneOntologyMolecularFunction	RNA uridylyltransferase activity	TUT4 TUT7	2.57e-04	3	186	2	GO:0050265
GeneOntologyMolecularFunction	glycogen phosphorylase activity	PYGB PYGM	2.57e-04	3	186	2	GO:0008184
GeneOntologyMolecularFunction	6-phosphofructokinase activity	PFKL PFKP	2.57e-04	3	186	2	GO:0003872
GeneOntologyMolecularFunction	protein serine kinase activity	STK17B CAMK2A SPEG TSSK2 TESK1 CDK10 FAM20C MAST4 IRAK4 ATM RPS6KL1	6.21e-04	363	186	11	GO:0106310
GeneOntologyMolecularFunction	1,4-alpha-oligoglucan phosphorylase activity	PYGB PYGM	8.47e-04	5	186	2	GO:0004645
GeneOntologyMolecularFunction	fructose-6-phosphate binding	PFKL PFKP	8.47e-04	5	186	2	GO:0070095
GeneOntologyMolecularFunction	AMP binding	PFKL PFKP PYGM	9.35e-04	21	186	3	GO:0016208
Domain	DUF3361	ELMO1 ELMO3	3.04e-04	3	189	2	IPR024574
Domain	6-Pfructokinase_euk	PFKL PFKP	3.04e-04	3	189	2	IPR009161
Domain	PHOSPHORYLASE	PYGB PYGM	3.04e-04	3	189	2	PS00102
Domain	Glycg_phsphrylas	PYGB PYGM	3.04e-04	3	189	2	IPR011833
Domain	Glyco_trans_35	PYGB PYGM	3.04e-04	3	189	2	IPR000811
Domain	PHOSPHOFRUCTOKINASE	PFKL PFKP	3.04e-04	3	189	2	PS00433
Domain	DUF3361	ELMO1 ELMO3	3.04e-04	3	189	2	PF11841
Domain	Phosphofructokinase_CS	PFKL PFKP	3.04e-04	3	189	2	IPR015912
Domain	PFK	PFKL PFKP	3.04e-04	3	189	2	PF00365
Domain	Phosphorylase	PYGB PYGM	3.04e-04	3	189	2	PF00343
Domain	ATP_PFK	PFKL PFKP	3.04e-04	3	189	2	IPR022953
Domain	Phosphofructokinase_dom	PFKL PFKP	3.04e-04	3	189	2	IPR000023
Domain	Kinase-like_dom	STK17B CAMK2A SPEG COQ8B TSSK2 TEK TESK1 CDK10 MAST4 COQ8A GUCY2D IRAK4 ATM PAN3 RPS6KL1	4.24e-04	542	189	15	IPR011009
Domain	PROTEIN_KINASE_DOM	STK17B CAMK2A SPEG COQ8B TSSK2 TEK TESK1 CDK10 MAST4 COQ8A GUCY2D IRAK4 PAN3 RPS6KL1	5.12e-04	493	189	14	PS50011
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MTA2 SEMA6C KCTD12 COL4A5 EPPK1 RHBDF2 MRPS12 ANKRD37 SPEG INTS1 PER1 MUS81 MIB2 TESK1 LYST ELAC2 ST14 ITPR2 KANSL3 FAM20C HEG1 CSAD NCAPD2 TIGD3 DIP2C PYGB PDZD8 SENP2 PC ABTB2 FOXK1 RASD2	1.22e-14	1105	190	32	35748872
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MTA2 KCTD12 TSPOAP1 CAMK2A RPS6 PFKL PFKP GDA ACOT11 PYGB PYGM GNAL RAB39B PC HDLBP	1.88e-06	621	190	15	22794259
Pubmed	Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.	MDC1 TNKS TNKS2	3.17e-06	6	190	3	26845027
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	ICAM1 CASP9 EZH2 ITGAE RAD1 MDC1 IRAK4 ATM	6.89e-06	179	190	8	19074885
Pubmed	Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.	CAMK2A DGKH GRM3 GNAL HTR3B	9.74e-06	52	190	5	19328558
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	ICAM1 PFKL PFKP TEK DDC ADRB3 GYS1 HTR3B	1.15e-05	192	190	8	20602615
Pubmed	Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk.	MUS81 BTBD2 ATM GEN1	1.37e-05	27	190	4	20610542
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MYO9A CAMK2A RALGAPB TSSK2 USP43 NUP62 PFKP TESK1 LYST MAST4 SYNE2 PAN3 PC GEN1 ABTB2 FOXK1	2.28e-05	861	190	16	36931259
Pubmed	Tankyrase is necessary for canonical Wnt signaling during kidney development.	TNKS TNKS2	2.97e-05	2	190	2	20549720
Pubmed	Interplay between the DNA damage proteins MDC1 and ATM in the regulation of the spindle assembly checkpoint.	MDC1 ATM	2.97e-05	2	190	2	24509855
Pubmed	Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.	TNKS TNKS2	2.97e-05	2	190	2	27494558
Pubmed	Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers.	MUC16 MUC5AC	2.97e-05	2	190	2	22220206
Pubmed	Association of GYS1 and beta(3)-AR gene with postprandial hyperglycemia and serum uric acid in type 2 diabetes mellitus.	ADRB3 GYS1	2.97e-05	2	190	2	12411100
Pubmed	Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1.	RPS6 ATM	2.97e-05	2	190	2	22451389
Pubmed	HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase.	GUCY2D CCL3	2.97e-05	2	190	2	19436054
Pubmed	TUT4/7-mediated uridylation of a coronavirus subgenomic RNAs delays viral replication.	TUT4 TUT7	2.97e-05	2	190	2	37085578
Pubmed	TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.	TUT4 TUT7	2.97e-05	2	190	2	25979828
Pubmed	Regulation of tankyrase activity by a catalytic domain dimer interface.	TNKS TNKS2	2.97e-05	2	190	2	30055800
Pubmed	EZH2 Loss Drives Resistance to Carboplatin and Paclitaxel in Serous Ovarian Cancers Expressing ATM.	EZH2 ATM	2.97e-05	2	190	2	31704732
Pubmed	Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.	TNKS TNKS2	2.97e-05	2	190	2	24291818
Pubmed	Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.	EZH2 EHMT2	2.97e-05	2	190	2	28246360
Pubmed	Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer.	MUC16 MUC5AC	2.97e-05	2	190	2	24722639
Pubmed	The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.	TUT4 TUT7	2.97e-05	2	190	2	28665939
Pubmed	Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.	TNKS TNKS2	2.97e-05	2	190	2	18612384
Pubmed	RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell type.	TUT4 TUT7	2.97e-05	2	190	2	34949722
Pubmed	Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy.	TNKS TNKS2	2.97e-05	2	190	2	28723574
Pubmed	TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway.	EZH2 TXNIP	2.97e-05	2	190	2	38884152
Pubmed	The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms.	MDC1 SENP2	2.97e-05	2	190	2	30796017
Pubmed	Alterations of the ocular surface epithelial MUC16 and goblet cell MUC5AC in patients with atopic keratoconjunctivitis.	MUC16 MUC5AC	2.97e-05	2	190	2	18782111
Pubmed	Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.	COQ8B COQ8A	2.97e-05	2	190	2	27499294
Pubmed	Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.	TNKS TNKS2	2.97e-05	2	190	2	18026951
Pubmed	Abnormal cardiac development in the absence of heart glycogen.	GYS1 PYGM	2.97e-05	2	190	2	15282316
Pubmed	Structural insights into SAM domain-mediated tankyrase oligomerization.	TNKS TNKS2	2.97e-05	2	190	2	27328430
Pubmed	Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.	MDC1 ATM	2.97e-05	2	190	2	20026654
Pubmed	Cancer antigen-125 and ICAM-1 are together responsible for ascites in liver cirrhosis.	ICAM1 MUC16	2.97e-05	2	190	2	24779300
Pubmed	Epithin/PRSS14 proteolytically regulates angiopoietin receptor Tie2 during transendothelial migration.	TEK ST14	2.97e-05	2	190	2	21097670
Pubmed	EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation.	MUS81 EZH2	2.97e-05	2	190	2	29035360
Pubmed	The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.	GNAL RASD2	2.97e-05	2	190	2	18035555
Pubmed	Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.	TNKS TNKS2	2.97e-05	2	190	2	24116873
Pubmed	Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1.	TNKS TNKS2	2.97e-05	2	190	2	15795250
Pubmed	Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes.	PYGB PYGM	2.97e-05	2	190	2	25130497
Pubmed	Uridylation by TUT4 and TUT7 marks mRNA for degradation.	TUT4 TUT7	2.97e-05	2	190	2	25480299
Pubmed	Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation.	TNKS TNKS2	2.97e-05	2	190	2	29263426
Pubmed	Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis.	TUT4 TUT7	2.97e-05	2	190	2	36497000
Pubmed	GC Gene Polymorphism and Unbound Serum Retinol-Binding Protein 4 Are Related to the Risk of Insulin Resistance in Patients With Chronic Hepatitis C: A Prospective Cross-Sectional Study.	RBP4 GUCY2D	2.97e-05	2	190	2	26962819
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO7B MYO9A MYO5C	5.59e-05	14	190	3	8022818
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAT4 WNT2B LAMA1 INTS1 COQ8B DGKH PFKL PFKP ITGAE ITPR2 FAM20C BTD ATM ZBTB11	5.86e-05	736	190	14	29676528
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MTA2 EPPK1 RPS6 TUT7 INTS1 PFKP MDC1 SYNE2 NCAPD2 PYGB ATM ZBTB11 HDLBP	6.86e-05	653	190	13	22586326
Pubmed	Defining the membrane proteome of NK cells.	MTA2 LONP2 RPS6 ICAM1 INTS1 B3GALT6 PFKL PFKP ELMO1 ITPR2 PLXNC1 GYS1 NCAPD2 MARF1 AGFG2 PYGB PDZD8 CORO7	8.00e-05	1168	190	18	19946888
Pubmed	USP25 regulates Wnt signaling by controlling the stability of tankyrases.	SENP2 TNKS TNKS2	8.53e-05	16	190	3	28619731
Pubmed	Assessment of mucin-related gene alterations following treatment with rebamipide ophthalmic suspension in Sjögren's syndrome-associated dry eyes.	MUC16 MUC5AC	8.87e-05	3	190	2	33232357
Pubmed	3' Uridylation Confers miRNAs with Non-canonical Target Repertoires.	TUT4 TUT7	8.87e-05	3	190	2	31178353
Pubmed	Inhibition of EZH2 attenuates coronary heart disease by interacting with microRNA-22 to regulate the TXNIP/nuclear factor-κB pathway.	EZH2 TXNIP	8.87e-05	3	190	2	33026112
Pubmed	mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome.	TUT4 TUT7	8.87e-05	3	190	2	28792939
Pubmed	Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation.	TNKS TNKS2	8.87e-05	3	190	2	32442396
Pubmed	Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.	PFKL PFKP	8.87e-05	3	190	2	7825568
Pubmed	DNAAF5 promotes hepatocellular carcinoma malignant progression by recruiting USP39 to improve PFKL protein stability.	PFKL DNAAF5	8.87e-05	3	190	2	36276075
Pubmed	Recruitment of histone methyltransferase G9a mediates transcriptional repression of Fgf21 gene by E4BP4 protein.	EHMT2 FGF21	8.87e-05	3	190	2	23283977
Pubmed	Chromosomal mapping of the tankyrase gene in human and mouse.	ADRB3 TNKS	8.87e-05	3	190	2	10198177
Pubmed	Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.	PFKL PFKP	8.87e-05	3	190	2	6444721
Pubmed	Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.	MDC1 ATM	8.87e-05	3	190	2	18006705
Pubmed	Investigation of genotype-phenotype relationship in Turkish patients with inherited retinal disease by next generation sequencing.	RDH12 EYS	8.87e-05	3	190	2	34315337
Pubmed	TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.	TUT4 TUT7	8.87e-05	3	190	2	36071058
Pubmed	Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene.	PFKL PFKP	8.87e-05	3	190	2	11137296
Pubmed	MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals.	MDC1 ATM	8.87e-05	3	190	2	16427009
Pubmed	Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs.	TUT4 TUT7	8.87e-05	3	190	2	23063654
Pubmed	Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.	TNKS TNKS2	8.87e-05	3	190	2	11739745
Pubmed	Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.	EZH2 EHMT2	8.87e-05	3	190	2	29053336
Pubmed	Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.	TNKS TNKS2	8.87e-05	3	190	2	25939383
Pubmed	Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.	MDC1 ATM	8.87e-05	3	190	2	20421415
Pubmed	Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex.	TNKS TNKS2	8.87e-05	3	190	2	33923443
Pubmed	A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.	EZH2 EHMT2	8.87e-05	3	190	2	24652950
Pubmed	TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.	TNKS TNKS2	8.87e-05	3	190	2	11454873
Pubmed	ATM kinase promotes both caspase-8 and caspase-9 activation during TNF-α-induced apoptosis of HeLa cells.	CASP9 ATM	8.87e-05	3	190	2	24530529
Pubmed	Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.	TNKS TNKS2	8.87e-05	3	190	2	21251231
Pubmed	Phosphofructokinase isozyme expression during myoblast differentiation.	PFKL PFKP	8.87e-05	3	190	2	2521854
Pubmed	Holliday junction-resolving enzymes-structures and mechanisms.	MUS81 GEN1	8.87e-05	3	190	2	27990631
Pubmed	MIP-1α enhances Jurkat cell transendothelial migration by up-regulating endothelial adhesion molecules VCAM-1 and ICAM-1.	ICAM1 CCL3	8.87e-05	3	190	2	25245399
Pubmed	Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.	PFKL PFKP	8.87e-05	3	190	2	33141153
Pubmed	Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s.	TUT4 TUT7	8.87e-05	3	190	2	30122351
Pubmed	Phosphofructokinase (PFK) isozymes in man. I. Studies of adult human tissues.	PFKL PFKP	8.87e-05	3	190	2	156693
Pubmed	Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.	TNKS TNKS2	8.87e-05	3	190	2	26246473
Pubmed	Isozymes of human phosphofructokinase in blood cells and cultured cell lines: molecular and genetic evidence for a trigenic system.	PFKL PFKP	8.87e-05	3	190	2	6451249
Pubmed	53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.	MDC1 ATM	8.87e-05	3	190	2	14695167
Pubmed	CAMK2A supported tumor initiating cells of lung adenocarcinoma by upregulating SOX2 through EZH2 phosphorylation.	CAMK2A EZH2	8.87e-05	3	190	2	32483123
Pubmed	Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions.	MUS81 GEN1	8.87e-05	3	190	2	24080495
Pubmed	Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.	TNKS TNKS2	8.87e-05	3	190	2	33361107
Pubmed	Knockdown of RNF2 enhances the radiosensitivity of squamous cell carcinoma in lung.	MDC1 ATM	8.87e-05	3	190	2	30673298
Pubmed	Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.	TNKS TNKS2	8.87e-05	3	190	2	27441654
Pubmed	Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.	PFKL PFKP	8.87e-05	3	190	2	2960695
Pubmed	Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex.	EZH2 EHMT2	8.87e-05	3	190	2	20005824
Pubmed	The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.	EZH2 EHMT2	8.87e-05	3	190	2	24389103
Pubmed	SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.	MUS81 GEN1	8.87e-05	3	190	2	28290553
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MTA2 EPPK1 PFKL PFKP ELAC2 GYS1 MDC1 NCAPD2 HDLBP	9.57e-05	332	190	9	32786267
Pubmed	HiPLA: High-throughput imaging proximity ligation assay.	EZH2 EHMT2 MDC1 ATM	1.18e-04	46	190	4	30419336
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	CAND2 BTBD2 BTBD3 PLXNC1 DNAH5	1.19e-04	87	190	5	37495603
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	COG2 CAND2 POLR2B COQ8B B3GALT6 NUP62 PFKP SORT1 DNAAF5 COQ8A NCAPD2 PC	1.37e-04	606	190	12	36538041
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	EPPK1 CAMK2A RPS6 PYGB PC	1.39e-04	90	190	5	35654790
Pubmed	Dengue hemorrhagic fever is associated with polymorphisms in JAK1.	ICAM1 ITGAE GUCY2D IRAK4 THAP12	1.47e-04	91	190	5	20588308
Pubmed	A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.	RPS6 PFKL PFKP ATM	1.63e-04	50	190	4	23703321
Interaction	TOP3B interactions	MTA2 SEMA6C KCTD12 COL4A5 EPPK1 RHBDF2 MRPS12 ANKRD37 SPEG INTS1 PER1 MUS81 MIB2 PFKL PFKP TESK1 LYST ELAC2 ST14 ITPR2 KANSL3 FAM20C HEG1 CSAD MDC1 NCAPD2 TIGD3 DIP2C PYGB PDZD8 SENP2 PC ABTB2 FOXK1 HDLBP RASD2	5.96e-08	1470	186	36	int:TOP3B
GeneFamily	Engulfment and cell motility proteins	ELMO1 ELMO3	1.44e-04	3	126	2	543
GeneFamily	Glycogen phosphorylases	PYGB PYGM	1.44e-04	3	126	2	437
GeneFamily	Non-canonical poly(A) polymerases	TUT4 TUT7	9.89e-04	7	126	2	1318
Coexpression	BARRIER_COLON_CANCER_RECURRENCE_DN	EPPK1 PFKL BTBD2 CDK10 ACOT11	2.69e-07	20	190	5	M5736
Coexpression	GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN	MUC16 SIVA1 PFKL OSGEP PFKP DPH5 SYNE2 TNKS2 SLC12A7 HDLBP	9.66e-07	183	190	10	M8178
Coexpression	GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN	RASA2 TSPOAP1 LONP2 MYO9A ANKRD37 ICAM1 COQ8B TSSK2 KANSL3 DNAAF5	2.16e-06	200	190	10	M9344
Coexpression	GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN	KCTD12 WNT2B SIVA1 PFKL PLXNC1 BTD MARF1 PYGM WIPI2 HDLBP	2.16e-06	200	190	10	M5188
Coexpression	GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN	ITGAE DDC INPP4B ELMO3 DPH5 MDC1 PAN3 SLC12A7 FOXK1	5.60e-06	175	190	9	M2940
Coexpression	GSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_UP	COG2 DGKH ITGAE ELAC2 DNAAF5 HEG1 MLC1 CORO7 SLC12A7	1.64e-05	200	190	9	M9380
Coexpression	FAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON	CAND2 TSPOAP1 SPEG DGKH PFKP GDA RPS6KL1 FOXK1	2.99e-05	166	190	8	M39026
Coexpression	PEDRIOLI_MIR31_TARGETS_DN	PADI4 CAND2 TSPOAP1 ICAM1 NOXA1 ZNF343 MIB2 STC1 CSAD GSTCD DIP2C CORO7	5.22e-05	413	190	12	M2494
Coexpression	GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_UP	TSSK2 LYST DDC ZNF707 UNC5A MAST4 KCNC2 GUCY2D	6.95e-05	187	190	8	M9225
Coexpression	GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN	SEMA6C COG2 RBP4 PFKL ADAMTSL3 EHMT2 GYS1 CCL3	9.99e-05	197	190	8	M8338
Coexpression	GSE14308_TH2_VS_TH17_DN	ANKRD37 RBM48 ITGAE IL18RAP KANSL3 HEG1 VIPAS39 KCNC2	1.07e-04	199	190	8	M3363
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_UP	NR2E3 TUT4 EPPK1 GDA FAM20C PLXNC1 CSAD MDC1	1.07e-04	199	190	8	M8255
Coexpression	GSE11924_TH2_VS_TH17_CD4_TCELL_UP	COG2 EPPK1 MYO9A RBP4 MUC16 PCDHA12 ADAMTSL3 ZNF707	1.07e-04	199	190	8	M3164
Coexpression	GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP	KCTD12 RUNDC3B IL18RAP LYST DDC DPH5 SEMA5B GNAL	1.07e-04	199	190	8	M5694
Coexpression	GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_DN	COQ8B PCDHA12 ITPR2 EHMT2 IFFO2 DIP2C GNAL SLC12A7	1.11e-04	200	190	8	M6360
Coexpression	HALLMARK_GLYCOLYSIS	COG2 B3GALT6 PFKP STC1 GYS1 PYGB PC HDLBP	1.11e-04	200	190	8	M5937
Coexpression	GSE17721_0.5H_VS_8H_CPG_BMDC_UP	SPEG PER1 CASP9 SIVA1 OSGEP ELAC2 SORT1 THAP12	1.11e-04	200	190	8	M4126
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 DUOX2 DGKH TEK BTBD3 TXNIP HEG1 PCSK6 PCDH1	1.68e-07	195	190	9	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TUT4 TSPOAP1 TUT7 TXNIP SYNE2 MARF1 SNU13 THAP12	9.66e-07	177	190	8	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TUT4 TSPOAP1 TUT7 TXNIP SYNE2 MARF1 SNU13 THAP12	9.66e-07	177	190	8	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	TUT4 TSPOAP1 TUT7 TXNIP SYNE2 MARF1 SNU13 THAP12	9.66e-07	177	190	8	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TUT4 TSPOAP1 TUT7 TXNIP SYNE2 MARF1 SNU13 THAP12	9.66e-07	177	190	8	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TUT4 TSPOAP1 TUT7 TXNIP SYNE2 MARF1 SNU13 THAP12	9.66e-07	177	190	8	d5aeda113afaa2425874394610344570c9078478
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAND2 DGKH MIB2 CLSTN2 GRM3 ADAMTSL3 FAM20C ATM	1.14e-06	181	190	8	274c0b768925cd5804483303f8c5ebd17a534c41
ToppCell	facs-Heart-RA-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM1 EYA1 TEK STC1 ITPR2 KCNC2 PLXNC1 SLC12A7	1.52e-06	188	190	8	4ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCell	facs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICAM1 EYA1 TEK STC1 ITPR2 KCNC2 PLXNC1 SLC12A7	1.52e-06	188	190	8	e47e66906922d5c69b1aafe28face0787d3fc563
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF32 EYA1 TEK LYST ITPR2 HEG1 KCNC2 PLXNC1	1.58e-06	189	190	8	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	ASK452-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	GIMAP2 RPS6 MUC16 USP9Y INPP4B TXNIP SYNE2 RAB39B	1.58e-06	189	190	8	f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 TUT4 DGKH TEK HEG1 MAST4 SYNE2 SEC14L1	2.41e-06	200	190	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FAT4 TUT4 DGKH TEK HEG1 MAST4 SYNE2 SEC14L1	2.41e-06	200	190	8	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	WNT2B ELMO1 SIGLEC7 CCL3 ADGRF1 PCDH1	3.33e-06	95	190	6	3d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 LYST ELMO1 ITPR2 DNAAF5 TNKS GNAL	6.82e-06	164	190	7	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 LYST ELMO1 ITPR2 DNAAF5 TNKS GNAL	6.82e-06	164	190	7	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 LYST ELMO1 ITPR2 DNAAF5 TNKS GNAL	6.82e-06	164	190	7	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|normal_Lung / Location, Cell class and cell subclass	NUGGC CXCR3 HUS1B DNPH1 EZH2 ITGAE ABTB2	9.67e-06	173	190	7	e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D CAND2 HUS1B MCM10 MAST4 ACOT11 PC	1.00e-05	174	190	7	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COQ8B CASP9 PFKP IL18RAP ST14 CCL3 PC	1.04e-05	175	190	7	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COQ8B CASP9 PFKP IL18RAP ST14 CCL3 PC	1.04e-05	175	190	7	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA6C CACNA1D COQ8B ZNF343 ST14 ZNF546 DIP2C	1.12e-05	177	190	7	3535575686c9700ab72700aae6f2070ebbb50044
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT4 RUNDC3B TEK ELMO1 MAST4 SYNE2 SEC14L1	1.21e-05	179	190	7	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	EZH2 GRPEL2 VIPAS39 MLC1 SYNE2 TNKS RABIF	1.34e-05	182	190	7	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	MYO7B MUC16 INPP4B GDA PCSK6 ADGRF1 MUC5AC	1.44e-05	184	190	7	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ICAM1 IL18RAP HEG1 SIGLEC7 MLC1 CCL3 ATM	1.55e-05	186	190	7	fc0b488c201a32d829047b58460297df2818b45d
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	STK17B PER1 ELMO1 ITPR2 TXNIP ATM SEC14L1	1.60e-05	187	190	7	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	KCTD12 FAT4 TEK ELMO1 MAST4 SYNE2 SEC14L1	1.60e-05	187	190	7	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ICAM1 IL18RAP HEG1 SIGLEC7 SYNE2 CCL3 ATM	1.60e-05	187	190	7	6981b856187a2e689260ecb7d0a1193a374ee9b9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASA2 MIB2 IL18RAP TXNIP MLC1 SYNE2 ATM	1.66e-05	188	190	7	f7dc29dfec68236883469e848be5db34f5526d6b
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	FAT4 ANKRD37 WNT2B TEK STC1 MAST4 SEC14L1	1.66e-05	188	190	7	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASA2 MIB2 IL18RAP TXNIP MLC1 SYNE2 ATM	1.66e-05	188	190	7	9abd78970bbe4ed03b59a83da63bbd334712f605
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASA2 MIB2 IL18RAP TXNIP MLC1 SYNE2 ATM	1.66e-05	188	190	7	5ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF32 EYA1 TEK LYST HEG1 KCNC2 PLXNC1	1.71e-05	189	190	7	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	RUNDC3B TEK LYST ELMO1 MYO5C STC1 HEG1	1.77e-05	190	190	7	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	ASK454-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	KCTD12 CATSPERD ANKRD37 CLSTN2 CFAP210 BTBD2 DNAH5	1.77e-05	190	190	7	5cea6480f08253d7adf484e511d3fdfa96641268
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP1 LRRTM1 NECTIN3 BTBD3 ITPR2 MAST4 SEC14L1	1.77e-05	190	190	7	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCTD12 TEK ITPR2 HEG1 MAST4 SYNE2 SEC14L1	1.83e-05	191	190	7	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A PPM1E LAMA1 ITPR2 MAST4 ACOT11 SYNE2	1.90e-05	192	190	7	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 RUNDC3B DGKH TEK ELMO1 BTBD3 SEC14L1	1.96e-05	193	190	7	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 RUNDC3B DGKH TEK ELMO1 BTBD3 SEC14L1	1.96e-05	193	190	7	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TSPOAP1 MIB2 IL18RAP MLC1 IFFO2 CCL3 PCDH1	1.96e-05	193	190	7	b53ffef20f918b7d1e9d3924562691d13245e2dd
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 DGKH TEK BTBD3 HEG1 PCDH1 SEC14L1	2.03e-05	194	190	7	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK-NK_CD16\|bone_marrow / Manually curated celltypes from each tissue	IL18RAP SIGLEC7 MLC1 SYNE2 CCL3 GNAL ATM	2.03e-05	194	190	7	7773501e076d470158dbc1d7f10c67152b326eb7
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	WNT2B TEK ELMO1 HEG1 SYNE2 PCDH1 SEC14L1	2.10e-05	195	190	7	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	DGKH USP9Y INPP4B TXNIP MAST4 SYNE2 ATM	2.10e-05	195	190	7	4bdedd924564a260841a9153604026b57487c83d
ToppCell	tumor_Lung-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	KCTD12 MYO7B ICAM1 LYST TXNIP RSPO3 GSTCD	2.10e-05	195	190	7	56f88ce95495260360bf08f9c76cc36e395dc6a9
ToppCell	lymphoid-NK_cell-NK_cell\|lymphoid / Lineage, cell class and subclass	ICAM1 MIB2 IL18RAP SIGLEC7 MLC1 CCL3 CORO7	2.17e-05	196	190	7	5e6238fe131e349013c60a73c99f84a6be7955ef
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16\|lymph-node_spleen / Manually curated celltypes from each tissue	IL18RAP SIGLEC7 MLC1 SYNE2 CCL3 GNAL PCDH1	2.17e-05	196	190	7	f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCell	Control-Lymphocyte-T_NK-NK\|Control / Disease, Lineage and Cell Type	MIB2 IL18RAP MLC1 SYNE2 CCL3 ATM PCDH1	2.17e-05	196	190	7	65838fddc920cdcecefe823f3ce1c95a7e50e82b
ToppCell	lymphoid-NK_cell\|lymphoid / Lineage, cell class and subclass	ICAM1 MIB2 IL18RAP SIGLEC7 MLC1 CCL3 CORO7	2.17e-05	196	190	7	0c7fb03ef782256f61624afc5c1bfaed9f1005fb
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KCTD12 MRPS12 RPS6 ICAM1 ITGAE LYST RSPO3	2.24e-05	197	190	7	143607d195c8aa2b94d995af0b2ef38582565611
ToppCell	mild_COVID-19_(asymptomatic)-NK\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TSPOAP1 IL18RAP MLC1 SYNE2 CCL3 GNAL ATM	2.31e-05	198	190	7	1e43181c13e054570046c7a973ddc1c586e259b0
ToppCell	normal_Lymph_Node-T/NK_cells-NK\|T/NK_cells / Location, Cell class and cell subclass	ICAM1 USP43 IL18RAP LYST SIGLEC7 MLC1 CCL3	2.31e-05	198	190	7	75e94298bf03d755fef46df685437d0d29fdbca9
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NUGGC CXCR3 HUS1B RPS6 IL18RAP INPP4B TXNIP	2.31e-05	198	190	7	6afb43c7c415c5bb7c577eab56653ede2b349524
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	NUGGC IL18RAP HEG1 MLC1 SYNE2 GSTCD GNAL	2.31e-05	198	190	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	(0)_NK_FCGR3Apos\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	IL18RAP TXNIP SIGLEC7 MLC1 SYNE2 CCL3 PCDH1	2.31e-05	198	190	7	13f10f9233fc1523f0da2d9d59f3ced9c51a603a
ToppCell	lymphoid-NK_cell-NK_cell\|NK_cell / Lineage, cell class and subclass	POLR2B PER1 EZH2 SYNE2 PDZD8 CCL3 CORO7	2.39e-05	199	190	7	945fbf5845403a8b22d04963f50ad69c414b6153
ToppCell	Healthy/Control-NK\|Healthy/Control / Disease group and Cell class	TSPOAP1 MIB2 IL18RAP MLC1 SYNE2 CCL3 GNAL	2.39e-05	199	190	7	e7fd91080fca7c31a2d48433791da3c2a4adf14d
ToppCell	Healthy_donor-NK\|Healthy_donor / disease group, cell group and cell class (v2)	TSPOAP1 MIB2 IL18RAP MLC1 SYNE2 CCL3 GNAL	2.39e-05	199	190	7	4892d85f7c8c00e5afdcea2cd7bae0074322fa52
ToppCell	Sepsis-URO-Lymphocyte-T/NK-dn_T\|URO / Disease, condition lineage and cell class	EZH2 GRPEL2 VIPAS39 MLC1 SYNE2 TNKS RABIF	2.47e-05	200	190	7	04ea6381b93a5d8bbeda4d71c788d7fbac6d40bc
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-NK\|Leuk-UTI / Disease, condition lineage and cell class	IL18RAP TXNIP MLC1 SYNE2 CCL3 ATM PCDH1	2.47e-05	200	190	7	bb37fed4872e71f413ae7c4aa12586fa31075334
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KCTD12 RASA2 MYO7B ANKRD37 PFKP MAST4 PCDH1	2.47e-05	200	190	7	c32ad15dede3f879007c0b856f2fed1f5b058103
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	LAMA1 EYA1 PFKP MAST4 MLC1 ACOT11 FXYD1	2.47e-05	200	190	7	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KCTD12 RASA2 MYO7B ANKRD37 PFKP MAST4 PCDH1	2.47e-05	200	190	7	8a2c6c53a39fab86750526083f7254b7413b29af
ToppCell	Mild/Remission-B_naive-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 TUT7 TXNIP COQ8A MARF1 THAP12	3.46e-05	143	190	6	bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 STK17B RDH12 IL18RAP GDA CCL3	4.20e-05	148	190	6	74f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCell	droplet-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCTD12 PADI4 STK17B RDH12 LYST GDA	5.05e-05	153	190	6	ce6e462ce4dbaf9d265f1f9e2f791efbba8c1dd0
ToppCell	droplet-Lung-3m-Hematologic-myeloid-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCTD12 PADI4 STK17B RDH12 LYST GDA	5.05e-05	153	190	6	9dba38574908f31a1194b8a339868f5e4be1be71
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO7B CASP9 BRINP1 TEK ELMO3 SEC61G	5.05e-05	153	190	6	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CACNA1D RUNDC3B CLSTN2 INPP4B KCNC2 GNAL	5.24e-05	154	190	6	df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 STK17B IL18RAP LYST GDA CCL3	5.43e-05	155	190	6	3f31f3c37eb40d5467def8506e349fa4b4695833
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GIMAP2 TEK ELMO1 GRPEL2 RAB39B SEC14L1	5.63e-05	156	190	6	f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCell	facs-Lung-EPCAM-24m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 TSPOAP1 STK17B RDH12 GDA CCL3	5.83e-05	157	190	6	d2cb261a9ee2c90e2e0fc656bd6413fbccb465fc
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 TSPOAP1 STK17B RDH12 GDA CCL3	5.83e-05	157	190	6	350069e4d2dbddc82e813e2a2cc43032daa23605
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEG CLSTN2 ADAMTSL3 ZNF546 SEMA5B ABTB2	5.83e-05	157	190	6	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD12 PADI4 STK17B RDH12 LYST GDA	6.04e-05	158	190	6	ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCTD12 PADI4 STK17B RDH12 LYST GDA	6.04e-05	158	190	6	d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCell	BAL-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	PADI4 PER1 MUC16 DPH5 CCL3 SLC12A7	6.71e-05	161	190	6	7a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SPEG USP9Y INPP4B KANSL3 SYNE2 ATM	6.94e-05	162	190	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	P07-Endothelial-lymphatic_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KCTD12 DUOX2 TXNIP RSPO3 PCSK6 ADGRF1	7.18e-05	163	190	6	5cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCell	P07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KCTD12 DUOX2 TXNIP RSPO3 PCSK6 ADGRF1	7.18e-05	163	190	6	322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RUNDC3B MIB2 MYO5C ZNF594 SIGLEC7 GNAL	7.18e-05	163	190	6	6c4d4c55fc8a731acca13c1ba7287f238a9d81e0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A LAMA1 C2CD4A GDA SYNE2 DNAH5	7.43e-05	164	190	6	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAND2 TEK STC1 ZBTB49 FAM20C MAST4	7.68e-05	165	190	6	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUGGC STK17B MIB2 IL18RAP MLC1 CCL3	8.21e-05	167	190	6	2ca1b994583edf4e197535ffac8fb0c1142f0dc1
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MTA2 GRPEL2 ZNF594 PCSK6 PYGM SLC12A7	8.48e-05	168	190	6	8f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 NR2E3 STK17B INPP4B CCL3 SLC12A7	8.48e-05	168	190	6	dc1143bd8db70c490167d73a525fd9b783eba960
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 NR2E3 STK17B INPP4B CCL3 SLC12A7	8.48e-05	168	190	6	a75d63ae8ad64b5560853775f6df398feb314ce8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KCTD12 SPEG WNT2B TEK ELMO1 HEG1	8.77e-05	169	190	6	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD8 ANKRD37 NECTIN3 ELMO1 BTBD3 PCDH1	8.77e-05	169	190	6	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD8 ANKRD37 NECTIN3 ELMO1 BTBD3 PCDH1	8.77e-05	169	190	6	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PFKP DNPH1 ZNF707 GDA GYS1 PC	9.06e-05	170	190	6	7534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 TUT7 TXNIP COQ8A MARF1 SNU13	9.35e-05	171	190	6	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 COQ8B PFKP IL18RAP LYST CCL3	9.66e-05	172	190	6	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 RASA2 TUT7 LYST GDA PLXNC1	9.66e-05	172	190	6	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 COQ8B PFKP IL18RAP LYST CCL3	9.66e-05	172	190	6	953b05f776348cff784e79c93df65841939d880f
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	TSPOAP1 MYO9A PER1 SORT1 FAM20C RAD1	9.97e-05	173	190	6	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A5 EYA1 GDA PCSK6 SYNE2 RPS6KL1	9.97e-05	173	190	6	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	HUS1B DNPH1 EZH2 MAST4 ACOT11 ABTB2	1.03e-04	174	190	6	e324320b52c904496e26fcecfa179b3431729ec0
Drug	1-GlcNAc	SPEG CSAD GYS1 PYGB PYGM	2.93e-07	18	189	5	CID000151446
Drug	Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; HL60; HT_HG-U133A	NR2E3 PPM1E PER1 ST14 STC1 SIGLEC7 PLXNC1 PCSK6 AGFG2 PYGB	3.53e-06	185	189	10	2532_UP
Drug	1-o-phosphonohex-2-ulose	PFKL PFKP GYS1 PYGB PYGM	3.78e-06	29	189	5	CID000000481
Drug	m-anisidine	GYS1 PYGB PYGM	5.56e-06	5	189	3	CID000010824
Drug	Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A	TMEM53 TSPOAP1 ICAM1 ADAMTSL3 KANSL3 PLXNC1 PCSK6 ZNF589 TNKS2 ADGRF1	5.89e-06	196	189	10	2628_UP
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	KCTD12 TMEM53 RUNDC3B TUT7 CASP9 SORT1 PLXNC1 ACOT11 PCSK6 ZNF589	6.74e-06	199	189	10	4843_DN
Drug	Cephaeline dihydrochloride heptahydrate [6487-30-5]; Up 200; 6uM; HL60; HT_HG-U133A	STK17B PER1 CASP9 RBM48 IL18RAP INPP4B MYO5C TXNIP SIGLEC7	7.94e-06	160	189	9	2429_UP
Drug	CV-araU	POLA2 PYGB PYGM	1.11e-05	6	189	3	CID006441877
Drug	5-chloro-indole-2-carboxylic acid	GYS1 PYGB PYGM	1.11e-05	6	189	3	CID000082693
Drug	2',3'-dideoxy-3'-fluorocytidine	DDC PYGB PYGM	1.92e-05	7	189	3	CID000356019
Drug	muraglitazar	CATSPERD LONP2 SPEG ICAM1 CLSTN2 PFKL IL18RAP TXNIP BTD FGF21 CSAD GYS1 CCL3 PC	2.20e-05	444	189	14	ctd:C500085
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A	EPPK1 STK17B ICAM1 PER1 CASP9 STC1 TXNIP AGFG2 ABTB2	2.32e-05	183	189	9	6874_UP
Drug	AC1L19C4	PFKL PFKP GYS1 PYGB PYGM PC	2.35e-05	69	189	6	CID000000483
Drug	Homochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; PC3; HT_HG-U133A	MTA2 NR2E3 TMEM53 EPPK1 RUNDC3B ICAM1 INPP4B MUC5AC SEC14L1	2.43e-05	184	189	9	7295_UP
Drug	AC1NUVX5	POLA2 PYGB PYGM	3.06e-05	8	189	3	CID005461894
Drug	Clidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	NR2E3 BTBD2 CDK10 ZNF589 GSTCD AGFG2 ATM PC SLC12A7	3.26e-05	191	189	9	6837_DN
Drug	5707885; Up 200; 50uM; MCF7; HT_HG-U133A	ICAM1 PPM1E STC1 TXNIP ADRB3 SIGLEC7 PCSK6 ZNF589 MUC5AC	3.68e-05	194	189	9	6385_UP
Drug	Halcinonide [3093-35-4]; Up 200; 8.8uM; PC3; HT_HG-U133A	CACNA1D TMEM53 STARD8 PER1 ITPR2 HEG1 MLC1 PCSK6 GNAL	3.68e-05	194	189	9	3680_UP
Drug	F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A	COL4A5 NECTIN3 STC1 ITPR2 TXNIP MAST4 SIGLEC7 CSAD AGFG2	3.83e-05	195	189	9	6424_DN
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; HL60; HT_HG-U133A	MTA2 CXCR3 TMEM53 TSPOAP1 STK17B PER1 CDK10 TXNIP FBXW11	3.99e-05	196	189	9	2396_DN
Drug	Tropine [120-29-6]; Down 200; 28.4uM; HL60; HT_HG-U133A	PADI4 RHBDF2 PPM1E SIVA1 ITPR2 IQCC PLXNC1 PCSK6 PYGB	3.99e-05	196	189	9	6147_DN
Drug	Quinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A	STK17B BEST2 SPEG ICAM1 PFKL ITPR2 MAST4 PLXNC1 MUC5AC	4.15e-05	197	189	9	3540_UP
Drug	staurosporine; Up 200; 1uM; MCF7; HG-U133A	PADI4 STARD8 BEST2 SPEG IL18RAP CDK10 ACOT11 PYGB HDLBP	4.15e-05	197	189	9	312_UP
Drug	felodipine; Up 200; 10uM; MCF7; HG-U133A	STARD8 CAND2 ICAM1 ITPR2 ELMO3 SIGLEC7 AGFG2 PYGM GNAL	4.15e-05	197	189	9	337_UP
Drug	troglitazone	CATSPERD LONP2 ANKRD37 SPEG ICAM1 CASP9 CLSTN2 PFKL POLA2 GRM3 EZH2 TEK IL18RAP ST14 STC1 SORT1 TXNIP ADRB3 PLXNC1 FGF21 PCSK6 TRIM17 MDC1 CCL3 PC FXYD1	4.19e-05	1329	189	26	ctd:C057693
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; HL60; HT_HG-U133A	MTA2 BEST2 PPM1E RBP4 TSSK2 IQCC PCSK6 GNAL SLC12A7	4.31e-05	198	189	9	2519_UP
Drug	Danazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MTA2 NR2E3 TMEM53 SPEG ICAM1 BRINP1 PCSK6 ATM TNKS2	4.31e-05	198	189	9	1538_UP
Drug	Cinoxacin [28657-80-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A	CACNA1D RASA2 MRPS12 BTBD3 ELMO3 MAST4 AGFG2 ATM PC	4.49e-05	199	189	9	3463_DN
Drug	NSC236997	COL4A5 ICAM1 DUOX2 PFKL MCM10 PFKP LYST SORT1 ADRB3 GYS1 GSTCD PYGB PYGM TNKS TNKS2	4.70e-05	539	189	15	CID000005300
Drug	Cefuroxime-d3	PER1 LYST IRAK4 RASD2	5.96e-05	26	189	4	CID000002658
Drug	UDP-pyridoxal	GYS1 PYGB PYGM	6.47e-05	10	189	3	CID000126789
Drug	phenanthridone	CASP9 TNKS TNKS2	6.47e-05	10	189	3	CID000001853
Drug	6-fluorocholesterol	LYST ATM	6.85e-05	2	189	2	CID000135206
Drug	25-fluorocholesterol	LYST ATM	6.85e-05	2	189	2	CID006454807
Drug	flavopiridol	STK17B CAMK2A POLR2B CASP9 CDK10 PYGB PYGM TNKS TNKS2	8.44e-05	216	189	9	CID005287969
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA	RUNDC3B INTS1 LYST TXNIP COQ8A ZNF589 MARF1 TNKS	1.06e-04	174	189	8	1019_UP
Drug	fullerene C60	CACNA1D STARD8 RHBDF2 TSPOAP1 BEST2 PER1 BBS1 NUP62 CFAP210 BTBD2 INPP4B KANSL3 TXNIP ZBTB49 GDA COQ8A EHMT2 MLC1 GYS1 TRIM17 TIGD3 CCL3 GNAL PAN3 SLC12A7 RABIF SEC14L1	1.18e-04	1498	189	27	ctd:C069837
Drug	2,5-anhydro-D-mannitol	PFKL PFKP PYGB PYGM	1.21e-04	31	189	4	CID000001494
Drug	thiamine	COL4A5 TESK1 TXNIP BTD PYGB PYGM PC	1.31e-04	134	189	7	CID000001130
Drug	maslinic acid	CASP9 PYGB CCL3	1.51e-04	13	189	3	CID000073659
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	TMEM53 RBP4 TSSK2 TXNIP COQ8A MARF1 TNKS WIPI2	1.75e-04	187	189	8	6995_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	RUNDC3B ICAM1 WNT2B PPM1E PER1 TXNIP IQCC MUC5AC	1.81e-04	188	189	8	3177_UP
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; HL60; HG-U133A	KCTD12 STK17B CAMK2A RALGAPB PER1 ST14 TXNIP ACOT11	1.81e-04	188	189	8	1395_UP
Drug	Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	SPEG ICAM1 LYST PCSK6 IRAK4 ATM MUC5AC WIPI2	1.88e-04	189	189	8	2231_UP
Drug	0297417-0002B [362658-29-5]; Up 200; 10uM; PC3; HT_HG-U133A	CXCR3 ICAM1 LYST STC1 ITPR2 HEG1 GNAL PCDHB1	1.88e-04	189	189	8	6895_UP
Drug	1,6-di-o-phosphonohexopyranose	PFKL PFKP GYS1 PYGB PYGM	1.92e-04	64	189	5	CID000000737
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; HL60; HT_HG-U133A	BEST2 ICAM1 WNT2B KANSL3 PLXNC1 PCSK6 AGFG2 GNAL	1.95e-04	190	189	8	2539_UP
Drug	Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A	LONP2 PER1 SORT1 TXNIP MAST4 BTD GSTCD WIPI2	1.95e-04	190	189	8	3833_DN
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	LONP2 TXNIP COQ8A BTD ZNF589 MARF1 GNAL SEC14L1	1.95e-04	190	189	8	6956_UP
Drug	3,5-dimethylphenyl isocyanate	PYGB PYGM	2.05e-04	3	189	2	CID000521488
Drug	5'-deoxy-5'-fluoro-5'-(methylthio)adenosine	PYGB PYGM	2.05e-04	3	189	2	CID000147839
Drug	NSC758405	PYGB PYGM	2.05e-04	3	189	2	CID000003201
Drug	3,5-dinitrophenyl phosphate	PYGB PYGM	2.05e-04	3	189	2	CID000151920
Drug	pyridoxal phosphoglucose	PYGB PYGM	2.05e-04	3	189	2	CID000196007
Drug	5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone	PYGB PYGM	2.05e-04	3	189	2	CID000093111
Drug	adenosine-5'-chloromethylphosphonate	PYGB PYGM	2.05e-04	3	189	2	CID000191554
Drug	hydan	PYGB PYGM	2.05e-04	3	189	2	CID000008360
Drug	EHMF	PYGB PYGM	2.05e-04	3	189	2	CID000033931
Drug	pyridoxal 5'-methylenephosphonate	PYGB PYGM	2.05e-04	3	189	2	CID003082249
Drug	Plp 5'-mpa	PYGB PYGM	2.05e-04	3	189	2	CID003082151
Drug	glucose-1,2-cyclic phosphate	PYGB PYGM	2.05e-04	3	189	2	CID000191723
Drug	3'-FFdUrd	PYGB PYGM	2.05e-04	3	189	2	CID000072260
Drug	2',3',4',5,5'-pentachloro-2-biphenylol	PYGB PYGM	2.05e-04	3	189	2	CID000119518
Drug	AC1L8XK3	PYGB PYGM	2.05e-04	3	189	2	CID000409735
Drug	N-acetyl-N'-beta-D-glucopyranosyl urea	PYGB PYGM	2.05e-04	3	189	2	CID000446801
Drug	riboflavin tetraacetate	PYGB PYGM	2.05e-04	3	189	2	CID000094186
Drug	2,5-dimethyl-3-furanone	PYGB PYGM	2.05e-04	3	189	2	CID000085730
Drug	3,5-dinitrophenol	PYGB PYGM	2.05e-04	3	189	2	CID000011459
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	RASA2 SIVA1 CLSTN2 TXNIP COQ8A CSAD PC WIPI2	2.10e-04	192	189	8	1059_UP
Drug	Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	RNF32 ICAM1 PER1 STC1 HEG1 SIGLEC7 PCSK6 PCDH1	2.10e-04	192	189	8	3635_UP
Drug	LY294002; Up 200; 10uM; MCF7; HG-U133A	SPEG CDK10 TXNIP SIGLEC7 COQ8A ACOT11 BTD FGF21	2.17e-04	193	189	8	318_UP
Drug	Oxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; PC3; HT_HG-U133A	SPEG PER1 BTBD2 CDK10 ZNF589 IRAK4 PC SLC12A7	2.17e-04	193	189	8	2114_DN
Drug	Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A	CXCR3 RHBDF2 RBM48 MYO5C SIGLEC7 PYGB SLC12A7 SEC14L1	2.17e-04	193	189	8	1183_UP
Drug	Penbutolol sulfate [38363-32-5]; Up 200; 5.8uM; MCF7; HT_HG-U133A	NR2E3 TUT4 SPEG ICAM1 PER1 STC1 HEG1 PLXNC1	2.17e-04	193	189	8	3534_UP
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A	MTA2 SIVA1 CLSTN2 SORT1 HEG1 ZNF589 GSTCD ATM	2.25e-04	194	189	8	3604_DN
Drug	phentolamine; Up 200; 11.5uM; MCF7; HT_HG-U133A_EA	TESK1 STC1 DPH5 CDC40 COQ8A PCSK6 TNKS ATM	2.25e-04	194	189	8	1138_UP
Drug	LY-171,883; Down 200; 1uM; MCF7; HG-U133A	ICAM1 CASP9 IL18RAP ITPR2 BTD GNAL HTR3B FXYD1	2.25e-04	194	189	8	222_DN
Drug	Carbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	RALGAPB SIVA1 LYST STC1 ITPR2 BTD ZNF589 FBXW11	2.33e-04	195	189	8	5399_DN
Drug	Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A	MTA2 BEST2 ICAM1 BRINP1 GRM3 PCSK6 GNAL SLC12A7	2.33e-04	195	189	8	3038_UP
Drug	Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; HL60; HT_HG-U133A	ICAM1 PER1 BTBD2 ITPR2 ACOT11 ZNF589 PYGB SEC14L1	2.33e-04	195	189	8	1298_UP
Drug	quinazolin-4(3H)-one	CLSTN2 TNKS TNKS2	2.38e-04	15	189	3	CID000063112
Drug	M 16209	PFKL PFKP GYS1	2.38e-04	15	189	3	CID000164260
Drug	Cocaine	RNF32 SEMA6C TUT4 TSPOAP1 CAMK2A ICAM1 TSSK2 PER1 CASP9 SIVA1 EYA1 PFKL DNPH1 GRM3 TESK1 ELMO1 FAM20C SEMA5B EHMT2 CSAD CCL3 ATM CORO7 ADGRF1	2.39e-04	1314	189	24	ctd:D003042
Drug	Niridazole [61-57-4]; Down 200; 18.6uM; HL60; HT_HG-U133A	CXCR3 TMEM53 RHBDF2 MRPS12 ICAM1 ITPR2 BTD PCSK6	2.41e-04	196	189	8	2440_DN
Drug	GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A	FAT4 EPPK1 SPEG HEG1 COQ8A AGFG2 SENP2 HDLBP	2.41e-04	196	189	8	6585_DN
Drug	Epicatechin-(-) [154-23-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	TSPOAP1 BEST2 ICAM1 BRINP1 ITPR2 KANSL3 PCSK6 MUC5AC	2.41e-04	196	189	8	4419_UP
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	MYO9A BTBD3 COQ8A PCSK6 PYGB ATM SLC12A7 RABIF	2.41e-04	196	189	8	1054_DN
Drug	Buspirone hydrochloride [33386-08-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A	MTA2 CASP9 LYST STC1 BTD ZNF589 ATM SEC14L1	2.41e-04	196	189	8	5343_UP
Drug	methyl methanesulfonate	NR2E3 MRPS12 MUS81 CASP9 POLA2 CDC40 RAD1 MDC1 TNKS ATM TNKS2	2.44e-04	364	189	11	CID000004156
Drug	Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A	KCTD12 WNT2B NECTIN3 USP9Y HEG1 SIGLEC7 PCSK6 PCDH1	2.49e-04	197	189	8	4727_UP
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A	NR2E3 TMEM53 RBM48 STC1 MAST4 ZNF589 MUC5AC ABTB2	2.49e-04	197	189	8	6440_UP
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	RNF32 SEMA6C CACNA1D TSPOAP1 ELMO1 SIGLEC7 PCSK6 PCDH1	2.49e-04	197	189	8	3616_UP
Drug	Indoprofen [31842-01-0]; Up 200; 14.2uM; HL60; HT_HG-U133A	TMEM53 RALGAPB ITPR2 BTD AGFG2 PYGB TNKS WIPI2	2.49e-04	197	189	8	3007_UP
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A	ICAM1 CLSTN2 ITPR2 ACOT11 ZNF589 AGFG2 ATM RABIF	2.49e-04	197	189	8	5576_DN
Drug	Fusidic acid sodium salt [751-94-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A	MTA2 CACNA1D PER1 SIVA1 LYST ATM PC PCDH1	2.49e-04	197	189	8	5353_UP
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A	SPEG PER1 ADAMTSL3 SORT1 ACOT11 IRAK4 AGFG2 ATM	2.49e-04	197	189	8	4690_UP
Drug	Polysaccharides	ICAM1 CASP9 PFKP PYGM PC	2.55e-04	68	189	5	ctd:D011134
Drug	Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	RUNDC3B MRPS12 STK17B PER1 CDK10 MAST4 BTD RABIF	2.58e-04	198	189	8	4825_DN
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A	TSPOAP1 NECTIN3 HEG1 PLXNC1 ZNF589 PCDH1 MUC5AC HDLBP	2.58e-04	198	189	8	3323_UP
Drug	Practolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A	PADI4 WNT2B MUC16 KANSL3 HEG1 ADRB3 PLXNC1 PCSK6	2.58e-04	198	189	8	4603_UP
Disease	nephrotic syndrome type 9 (implicated_via_orthology)	COQ8B COQ8A	3.66e-05	2	179	2	DOID:0080391 (implicated_via_orthology)
Disease	primary coenzyme Q10 deficiency 4 (implicated_via_orthology)	COQ8B COQ8A	3.66e-05	2	179	2	DOID:0070241 (implicated_via_orthology)
Disease	Retinitis Pigmentosa	NR2E3 RBP4 BBS1 RDH12 EYS GUCY2D	4.25e-05	104	179	6	C0035334
Disease	smoking behavior, BMI-adjusted waist circumference	EYA1 ADAMTSL3 STC1 RSPO3 FBXW11 HDLBP	1.03e-04	122	179	6	EFO_0004318, EFO_0007789
Disease	BMI-adjusted waist circumference, physical activity measurement	WNT2B EYA1 ADAMTSL3 STC1 RSPO3 FBXW11	1.08e-04	123	179	6	EFO_0007789, EFO_0008002
Disease	keratoconjunctivitis (is_marker_for)	MUC16 MUC5AC	1.09e-04	3	179	2	DOID:9368 (is_marker_for)
Disease	Bipolar Disorder	KCTD12 CACNA1D CAMK2A DGKH PFKL GRM3 DDC MLC1 GNAL HTR3B PC	1.71e-04	477	179	11	C0005586
Disease	glycogen storage disease (implicated_via_orthology)	PFKL PFKP	2.18e-04	4	179	2	DOID:2747 (implicated_via_orthology)
Disease	seborrheic dermatitis	GRM3 MAST4 SENP2	2.32e-04	20	179	3	EFO_1000764
Disease	systemic scleroderma (is_marker_for)	CXCR3 ICAM1 RBP4 CCL3	3.04e-04	53	179	4	DOID:418 (is_marker_for)
Disease	plasminogen activator inhibitor 1 measurement	CDK10 INPP4B MLC1 IFFO2	3.27e-04	54	179	4	EFO_0004792
Disease	hyperinsulinism (is_marker_for)	RBP4 DDC	3.62e-04	5	179	2	DOID:2018 (is_marker_for)
Disease	uric acid measurement	FAT4 MYO9A POLA2 EZH2 STC1 RSPO3 GUCY2D DIP2C PYGB PYGM SENP2 FOXK1	3.72e-04	610	179	12	EFO_0004761
Disease	Sjogren's syndrome (is_marker_for)	ICAM1 MUC16 MUC5AC	4.05e-04	24	179	3	DOID:12894 (is_marker_for)
Disease	Glycogen Storage Disease	PFKL GYS1 PYGM	5.77e-04	27	179	3	C0017919
Disease	coenzyme Q10 deficiency disease (implicated_via_orthology)	COQ8B COQ8A	7.53e-04	7	179	2	DOID:0050730 (implicated_via_orthology)
Disease	response to angiotensin receptor blocker	CACNA1D WNT2B RSPO3	7.90e-04	30	179	3	EFO_0010735
Disease	Malignant neoplasm of breast	STARD8 RPS6 PPM1E PER1 EZH2 TEK TESK1 INPP4B ZNF546 RSPO3 SEMA5B SYNE2 DIP2C ATM GEN1 HDLBP	8.86e-04	1074	179	16	C0006142
Disease	alcoholic hepatitis (is_marker_for)	ICAM1 CCL3	1.00e-03	8	179	2	DOID:12351 (is_marker_for)
Disease	diffuse large B-cell lymphoma (is_marker_for)	ICAM1 EZH2	1.00e-03	8	179	2	DOID:0050745 (is_marker_for)
Disease	renal Wilms' tumor (is_implicated_in)	EZH2 TEK	1.59e-03	10	179	2	DOID:5176 (is_implicated_in)
Disease	dry eye syndrome (is_marker_for)	MUC16 MUC5AC	1.59e-03	10	179	2	DOID:10140 (is_marker_for)
Disease	cancer antigen 125 measurement	MUC16 MSLNL	1.59e-03	10	179	2	EFO_0010603
Disease	smoking behavior, BMI-adjusted waist-hip ratio	EYA1 STC1 RSPO3 EHMT2	1.89e-03	86	179	4	EFO_0004318, EFO_0007788
Disease	Disorder of eye	NR2E3 RBP4 BBS1 RDH12 EYS GUCY2D	1.92e-03	212	179	6	C0015397
Disease	epilepsy	GRM3 MAST4 TNKS	1.98e-03	41	179	3	EFO_0000474
Disease	Nodular glomerulosclerosis	DGKH ELMO1 TXNIP	1.98e-03	41	179	3	C0017667
Disease	renal cell carcinoma	MYO7B ITPR2 ATM	2.12e-03	42	179	3	EFO_0000681
Disease	diffuse plaque measurement	KCTD12 BRINP1 C1orf167 GRM3 ITPR2 GDA EYS MAST4 KCNC2 EHMT2 PLXNC1 ZNF589	2.38e-03	758	179	12	EFO_0010699
Disease	Diabetic Nephropathy	DGKH ELMO1 TXNIP	2.42e-03	44	179	3	C0011881
Disease	Leber congenital amaurosis (implicated_via_orthology)	RDH12 GUCY2D	2.73e-03	13	179	2	DOID:14791 (implicated_via_orthology)
Disease	Chromosome Breakage	EZH2 EHMT2	3.17e-03	14	179	2	C0376628
Disease	Chromosome Breaks	EZH2 EHMT2	3.17e-03	14	179	2	C0333704
Disease	PR interval	CACNA1D RUNDC3B DNPH1 ELMO1 COQ8A SYNE2 SENP2 SLC12A7 THAP12	3.38e-03	495	179	9	EFO_0004462
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	RSPO3 FGF21 SYNE2 TNKS TNKS2	3.50e-03	166	179	5	EFO_0004530, EFO_0004611
Disease	malaria	NUGGC DDC INPP4B DIP2C	3.51e-03	102	179	4	EFO_0001068
Disease	response to peritoneal dialysis, peritoneal solute transfer rate	GIMAP2 KCNC2	3.65e-03	15	179	2	EFO_0600089, EFO_0600090
Disease	hepcidin:transferrin saturation ratio	MUC16 PAN3	3.65e-03	15	179	2	EFO_0007902
Disease	Ischemic stroke	WNT2B EYA1 TEK ADAMTSL3 GDA HTR3B ADGRF1	3.76e-03	324	179	7	HP_0002140
Disease	susceptibility to bacterial meningitis measurement	CACNA1D INPP4B DNAH5	3.90e-03	52	179	3	EFO_0008411
Disease	Leber congenital amaurosis	RDH12 GUCY2D	4.15e-03	16	179	2	cv:C0339527
Disease	diabetic retinopathy (is_marker_for)	ICAM1 RBP4 CASP9	4.34e-03	54	179	3	DOID:8947 (is_marker_for)
Disease	Acute Cerebrovascular Accidents	CXCR3 ICAM1 WNT2B	4.34e-03	54	179	3	C0751956
Disease	Peripheral Nervous System Diseases	ICAM1 CASP9 LYST	4.34e-03	54	179	3	C4721453
Disease	Ciliopathies	BBS1 RDH12 GUCY2D DNAH5	4.59e-03	110	179	4	C4277690
Disease	MAJOR AFFECTIVE DISORDER 2	DDC MLC1	4.69e-03	17	179	2	C1839839
Disease	Muscle hypotonia	INTS1 DDC	4.69e-03	17	179	2	C0026827
Disease	gestational diabetes (is_marker_for)	ICAM1 RBP4	4.69e-03	17	179	2	DOID:11714 (is_marker_for)
Disease	protein C measurement	MYO7B ELMO1	4.69e-03	17	179	2	EFO_0004633
Disease	Brain Ischemia	ICAM1 CASP9 CCL3	5.83e-03	60	179	3	C0007786
Disease	Cerebral Ischemia	ICAM1 CASP9 CCL3	5.83e-03	60	179	3	C0917798
Disease	acute lymphoblastic leukemia, response to antineoplastic agent	ELMO1 INPP4B	5.85e-03	19	179	2	EFO_0000220, GO_0097327

Protein segments in the cluster

Peptide	Gene	Start	Entry
LARNCGRESRVDVAK	CXCR3	286	P49682
GRRLSFLLRKNSCVS	BEST2	411	Q8NFU1
ATLAREGRLCKREVQ	B3GALT6	291	Q96L58
LADRRTGTLRKCLEQ	C1orf167	706	Q5SNV9
QRLNRLVEGTCFRKL	ELMO1	551	Q92556
LVEGTCFRKLNARRR	ELMO1	556	Q92556
QLCRSRTVRTGKVFN	CATSPERD	21	Q86XM0
GRAVAFNKRILCLFR	DNPH1	106	O43598
IQRTARKLFGLSVRC	BRINP1	356	O60477
GLIRIIRAKATTDCN	ADGRF1	81	Q5T601
NCRARIVFKTSVLVG	HTR3B	266	O95264
LRNICIATAEKVGRS	GRM3	236	Q14832
RCEEKTVGRLFTIGR	FAT4	1671	Q6V0I7
TLSCRGVRQKIREAK	CCDC96	536	Q2M329
NVCKALATFVARREI	ACOT11	141	Q8WXI4
RGRCDSIQFAVDKRV	BTBD3	391	Q9Y2F9
VGNRAIRTEKIICRD	EHMT2	911	Q96KQ7
GALVTKRCARTAVVL	ADRB3	146	P13945
AGVRRLKVSSKVQCF	CLSTN2	596	Q9H4D0
RDKFVLRFAICSRTV	DDC	441	P20711
CVAVLRQKRSLGSVE	ANKRD37	136	Q7Z713
TDTKGKCRFRAIVRS	CPXCR1	221	Q8N123
KCRFRAIVRSVLFVS	CPXCR1	226	Q8N123
KSCLIRRFTEGRFAQ	RAB39B	21	Q96DA2
VQRAVCDTRAKYREG	RBM48	16	Q5RL73
GNVEAKVVCLFRRRD	MTA2	36	O94776
GCSGFFKRSVRRRLI	NR2E3	66	Q9Y5X4
VTVQCAFTVALRARR	NOXA1	316	Q86UR1
SREVRVLQSLRGKIC	RASA2	31	Q15283
VLSCKVSIRTDNRGF	RAD1	236	O60671
RECRELQARLTLVGK	TSPOAP1	236	O95153
LVRKVSALQACVRGF	IQCC	6	Q4KMZ1
CIRTLAEVAKNRGIA	ITPR2	1536	Q14571
IRDRDIRVGGKVTCF	PCDHB1	371	Q9Y5F3
TVKGLEVVRRCSRVY	DPH5	16	Q9H2P9
VRVFQATRGKLSSKC	PADI4	211	Q9UM07
SRGARVYIACRDVLK	RDH12	61	Q96NR8
ARYTGCRVIALRSVK	MUC16	13971	Q8WXI7
KAGRTITARITGRCD	POC5	481	Q8NA72
VTQRDLRRKFVCFVQ	IL18RAP	326	O95256
RDKNRRGETCFLLTT	KCNC2	566	Q96PR1
ERQLCFRTKRSASLG	LNP1	116	A1A4G5
VRSLDRKLGAICRAV	LONP2	561	Q86WA8
LVTDRIRRTVKFLCA	MDC1	1926	Q14676
SSFINGKTCRRQLVE	EYS	16	Q5T1H1
CIRVLLGKSREQRFD	INTS1	1676	Q8N201
RLKSRNCIVDGRFVL	GUCY2D	666	Q02846
ICSVQGDAFQKLRRV	LRRTM1	101	Q86UE6
CRLRGLVQFVKSITL	LRIT2	206	A6NDA9
LAATICRKLNGIRFT	INPP4B	826	O15327
VSAEGRNRKAVLCQR	RABIF	11	P47224
GIRDIFKQNISCRVS	DUOX2	951	Q9NRD8
QLATVCKDGRVRVYR	CORO7	651	P57737
VDVGKQRRRLQCSDV	ITGAE	731	P38570
RLIGTKTCRQVYEFR	EZH2	456	Q15910
LLRCKRDVFRGTRFS	PER1	241	O15534
RKIVTTDLRQRCTDG	PCSK6	401	P29122
LTAGKEVRRIRVANC	PLXNC1	441	O60486
RIRSVEGRKKAFSTC	OR3A2	236	P47893
AVLVRYCRQREAKSG	PCDH1	871	Q08174
CGATDRRIDRTLKNL	PDZD8	891	Q8NEN9
SARCKAFTTREGRRA	PFKL	86	P17858
ARCQAFRTREGRLKA	PFKP	96	Q01813
VRCIRFDNKRIVSGA	FBXW11	446	Q9UKB1
IQILGVKTSRFLCQR	FGF21	91	Q9NSA1
SCFERIIQRFGRKVV	EYA1	536	Q99502
GILIVLSRRCRCKFN	FXYD1	51	O00168
VFVRSKQALGRACGV	SNU13	81	P55769
KERRVQRIQESTCFS	MCM10	161	Q7L590
TYNNIIRSGEKICRR	MUC5AC	3546	P98088
RLGQREARCFVTSFL	MSLNL	276	Q96KJ4
SQRRIFRAGSLCKRK	HEG1	1166	Q9ULI3
CEGRRKEQERSFRIT	NUP62	506	P37198
RIRSLQGRLKAFTTC	OR13H1	226	Q8NG92
DCTKRNNRSTVFRIV	DGKH	1116	Q86XP1
AVGNCLDRFARVLKI	OSGEP	156	Q9NPF4
RRRTQRCVEDAKIFG	GRPEL2	91	Q8TAA5
ECRINSGEEVLRKRF	THAP12	206	O43422
RFVQKAARESLRCGT	PPM1E	316	Q8WY54
RCRVLTSGIFETRFQ	GNAL	186	P38405
KTRLRVNCVGVFDVL	PAN3	651	Q58A45
KTLAVNFRIRVCELG	ATM	241	Q13315
QCASRSELRIILVGK	GIMAP2	16	Q9UG22
GRCRSVKEFEKLNRI	CDK10	31	Q15131
RVVLKAVRDCVERNG	FAM20C	551	Q8IXL6
TGSNIDCEKLRRRFS	CASP9	181	P55211
LKAGDLRTRISRCQV	COL4A5	1666	P29400
ERIVRTLCKVRGAAL	COQ8A	261	Q8NI60
KARGLDLSRVRTCVV	DIP2C	1251	Q9Y2E4
EQAFRKRRQRGVSCF	FOXK1	391	P85037
IQGGRRAKSRFVVCI	BTD	6	P43251
GVIFLTKRSRQVCAD	CCL3	61	P10147
RIVQTLCTVRGAALK	COQ8B	141	Q96D53
LRLCEGTLFRKISSR	ELMO3	541	Q96BJ8
LERCRAVIRYSVKTG	CSAD	71	Q9Y600
KSRVIRDLFLSCNGV	LYST	786	Q99698
ETCRRLIKGSADRNS	IFFO2	471	Q5TF58
KSVSNRLRRLSDNCG	MARF1	526	Q9Y4F3
RRGSFCRTSNRKSLI	MAST4	221	O15021
GTVARLAKVCVLRVR	HUS1B	21	Q8NHY5
RIVKTRIRNGVHCFE	GEN1	401	Q17RS7
RVVRRTLKNGTTTAC	GDA	126	Q9Y2T3
VDKCARRVRQALASV	KANSL3	171	Q9P2N6
LCRARSTQGEVTRKV	ICAM1	456	P05362
VRCLNVGLIRKLSDF	IRAK4	11	Q9NWZ3
VRRLERQCGSQASVK	COG2	351	Q14746
VLGCRELVFRNLSKI	DNAAF5	346	Q86Y56
RRIGLFNSSADRVKV	GYS1	461	P13807
DRIRFSVNKRIFVVG	BTBD2	391	Q9BX70
ACRNGNIYILRRDSK	BBS1	266	Q8NFJ9
KDRSVRARQGCFSLL	CAND2	446	O75155
GNRTLSRRSFDACVK	SLC12A7	311	Q9Y666
RRCEENTKVFGRPIS	SEC14L1	376	Q92503
RSDNFCRAGLAVVLR	GSTCD	96	Q8NEC7
ADAKFRRVARITVCG	KCTD12	226	Q96CX2
RRVARITVCGKTSLA	KCTD12	231	Q96CX2
RQCSTVVGRSRKASF	C2CD4A	306	Q8NCU7
FNRRRCRAAVKSVTF	CACNA1D	511	Q01668
SVFRCVRLLRIFKVT	CACNA1D	616	Q01668
RQIIIRVKLASCGFI	DNAH5	2111	Q8TE73
VNSRIDREKLCGRSA	PCDHA12	86	Q9UN75
RVLKALQGCAQRFRE	MIB2	781	Q96AX9
ARLACASIKVNIRFG	OR52E8	191	Q6IFG1
VERRNLITVCRFSVK	RUNDC3B	31	Q96NL0
VRILGTIFRFCDRSV	SENP2	6	Q9HC62
QFLRLRKSSVCQNGR	SORT1	641	Q99523
CQRGFCRDVALVVTK	NUGGC	341	Q68CJ6
ERKRKSVRGCIVDAN	RPS6	91	P62753
FQRRRTTCALTLEAG	SYNE2	5751	Q8WXH0
RSQTSFRGCLRKLAL	LAMA1	3031	P25391
ERRCLRTFIGHSKAV	CDC40	321	O60508
LSKVSFRGLRCQVSA	EPPK1	3236	P58107
RGKFAVVRQCISKST	STK17B	41	O94768
GARLFRIKCVTRIQA	RNF32	181	Q9H0A6
ECRGCRNKTQISLVR	POLR2B	1136	P30876
ISKVVYRSCNGRDRL	SETD9	191	Q8NE22
VIFIVVRSCRKKSAR	SIGLEC7	371	Q9Y286
QKLFEFRRGVKRCVS	WIPI2	236	Q9Y4P8
IFKQCLRTIIEGTRS	POLA2	401	Q14181
KGAFSVVRRCVKVLA	CAMK2A	21	Q9UQM7
LRSQCLDQVGIFRKS	STARD8	596	Q92502
CRVRLSTGREAVCFI	MRPS12	81	O15235
NGVTSKVFLAIRRCS	STC1	101	P52823
AKCTRFEVQSAVRLV	ABTB2	151	Q8N961
VVFLQSRGNEVCRKI	AGFG2	96	O95081
FGRRCGRAKESTEIR	CFAP210	11	Q0VFZ6
LVEKLCQRFRTSRTE	NCAPD2	1206	Q15021
AIITARNLICERTGK	SLC35G4	321	P0C7Q5
QVLLCANSRGTEKRR	TIGD3	196	Q6B0B8
RRKQRAVELSFICGT	ZNF707	166	Q96C28
RECRRGFSQKSNLIR	ZNF343	496	Q6P1L6
RFCQVGERRNKLSTL	USP43	591	Q70EL4
RTKREFICSICGRTL	ZBTB11	646	O95625
RRGVRDSSLVVAFIC	ELAC2	231	Q9BQ52
QDIIRRFKSSKFGCR	PYGM	306	P11217
RACRENATGRTFVAK	SPEG	2981	Q15772
SRQFVKDSIRLVKRC	SEC61G	11	P60059
GRAERDCRVSSFRVK	RBP4	16	P02753
LLEACRNGDVSRVKR	TNKS	186	O95271
QFTCRTGRCIRKELR	ST14	456	Q9Y5Y6
RFCRLRVVGTIFDSA	TMEM53	131	Q6P2H8
CGKAFSRVRDLRVHQ	ZNF546	306	Q86UE3
QDIIRRFKSSKFGCR	PYGB	306	P11216
VLREGQARERDKCTI	RASD2	251	Q96D21
CGFKRGTETRVREII	RSPO3	166	Q9BXY4
GRVQFSRVARVCKRD	SEMA6C	251	Q9H3T2
RTLSSAVEQLRGCRV	RPS6KL1	141	Q9Y6S9
LTSKNCLVRREDRGF	TESK1	176	Q15569
GRTVYSRVARVCKND	SEMA5B	311	Q9P283
SRVARVCKNDVGGRF	SEMA5B	316	Q9P283
SRDCELGFRVRKRTC	SEMA5B	866	Q9P283
VRRLRKGKVCSLERF	VIPAS39	161	Q9H9C1
SAFTRLIVRRCEAQK	TEK	201	Q02763
DTIGSVRRCIVNRIK	USP9Y	911	O00507
GFLVRQTVINICRRK	RALGAPB	1431	Q86X10
ACRNGDVERVKRLVT	TNKS2	31	Q9H2K2
CVAKNIVARRRSASA	UNC5A	221	Q6ZN44
ALGVCRDNVSRKDRV	TRIM17	366	Q9Y577
TECGKAFRRRSLLIQ	ZNF594	491	Q96JF6
EICNKCFTRSAVLRR	ZBTB49	566	Q6ZSB9
GKRANCEAARSRILS	HDLBP	631	Q00341
RECGRGFSRKSQLII	ZNF589	251	Q86UQ0
GRVSVSARIDRKGFC	TXNIP	176	Q9H3M7
RGCRTVRRLFHKDLT	TUT7	146	Q5VYS8
VVCRDRKSGLLCRVS	TUT4	456	Q5TAX3
SVLDATGQRCRVVKR	RHBDF2	256	Q6PJF5
GFSKRCLRDSNGRII	TSSK2	156	Q96PF2
RVFRACTELGIRTVA	PC	51	P11498
LKVRVSQRELSRGVC	SIVA1	16	O15304
NNRCGRTAVRRFLKL	WNT2B	221	Q93097
NRRVTCRQLLTDGSF	ADAMTSL3	781	P82987
GTAIQCVRFKVSARL	MLC1	321	Q15049
CSSIIDGRFREQKFR	MUS81	341	Q96NY9
FDSKRIVQQLRACGV	MYO5C	661	Q9NQX4
CNRRNFKLILVGFER	MYO7B	801	Q6PIF6
KIILLQSTCRGFRAR	MYO9A	1141	B2RTY4
TRFARGRRITCVVKH	NECTIN3	236	Q9NQS3