Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.53e-07	10	120	4	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.53e-07	10	120	4	GO:0005391
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.96e-07	11	120	4	GO:0008556
GeneOntologyMolecularFunction	steroid hormone binding	ATP1A1 ATP1A2 ATP1A3	7.28e-06	7	120	3	GO:1990239
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	COX15 UQCR10 NDUFV1 SLC5A3 SLC5A6 SLC22A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.40e-05	301	120	10	GO:0022853
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP1A1 ATP1A2 ATP1A3 ATP1A4	6.30e-05	36	120	4	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP1A1 ATP1A2 ATP1A3 ATP1A4	6.30e-05	36	120	4	GO:0015662
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC5A3 SLC5A6 SLC22A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4	7.89e-05	171	120	7	GO:0015081
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	COX15 UQCR10 NDUFV1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.01e-04	178	120	7	GO:0015399
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	COX15 UQCR10 NDUFV1 RYR2 SLC5A3 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.03e-04	627	120	13	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	COX15 UQCR10 NDUFV1 RYR2 SLC5A3 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.81e-04	664	120	13	GO:0008324
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	LONP2 DDX60 CHD4 RAB6B DDX1 MFN1 MFN2 MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 RAB6A RASD2	2.33e-04	775	120	14	GO:0017111
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC43A2 CEACAM8 COX15 SLC35F1 UQCR10 NDUFV1 RYR2 SLC5A3 GJA5 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 MFSD10	2.38e-04	1180	120	18	GO:0022857
GeneOntologyMolecularFunction	ATP-dependent activity	MYO6 LONP2 DDX60 CHD4 DDX1 ACSL1 CHTF8 MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.29e-04	614	120	12	GO:0140657
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	RYR2 SLC5A3 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	5.04e-04	465	120	10	GO:0046873
GeneOntologyMolecularFunction	pyrophosphatase activity	LONP2 DDX60 CHD4 RAB6B DDX1 MFN1 MFN2 MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 RAB6A RASD2	5.16e-04	839	120	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	LONP2 DDX60 CHD4 RAB6B DDX1 MFN1 MFN2 MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 RAB6A RASD2	5.22e-04	840	120	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	LONP2 DDX60 CHD4 RAB6B DDX1 MFN1 MFN2 MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 RAB6A RASD2	5.22e-04	840	120	14	GO:0016818
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP1A1 ATP1A2 ATP1A3 ATP1A4	5.29e-04	62	120	4	GO:0019829
GeneOntologyMolecularFunction	active transmembrane transporter activity	COX15 UQCR10 NDUFV1 SLC5A3 SLC5A6 SLC22A3 ATP1A1 ATP1A2 ATP1A3 ATP1A4	6.14e-04	477	120	10	GO:0022804
GeneOntologyMolecularFunction	actin binding	XIRP1 MYO6 CEACAM8 MYOZ3 KLHL20 DST KCNMA1 MACF1 CTNNA2 KLHL17	6.34e-04	479	120	10	GO:0003779
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	COX15 UQCR10 NDUFV1 RYR2 SLC5A3 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	6.40e-04	758	120	13	GO:0015318
GeneOntologyMolecularFunction	transporter activity	SLC43A2 CEACAM8 COX15 SLC35F1 UQCR10 NDUFV1 RYR2 SLC5A3 GJA5 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 MFSD10	6.82e-04	1289	120	18	GO:0005215
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	CEACAM8 SLC5A3 SLC22A3 MFSD10	8.38e-04	70	120	4	GO:1901618
GeneOntologyMolecularFunction	cytoskeletal protein binding	CCDC170 XIRP1 MYO6 CEP290 CEACAM8 MYOZ3 RAB6B KLHL20 DST KCNMA1 MACF1 CTNNA2 ATP1A1 RAB6A MAPK8IP2 KLHL17	8.95e-04	1099	120	16	GO:0008092
GeneOntologyMolecularFunction	electron transfer activity	COX15 UQCR10 NDUFV1 RDH16 HAAO	9.18e-04	124	120	5	GO:0009055
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	COX15 UQCR10 NDUFV1 RYR2 SLC5A3 SLC5A6 SLC22A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	9.69e-04	793	120	13	GO:0015075
GeneOntologyMolecularFunction	ATP hydrolysis activity	LONP2 DDX60 CHD4 DDX1 MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.39e-03	441	120	9	GO:0016887
GeneOntologyBiologicalProcess	intracellular potassium ion homeostasis	KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.44e-08	17	119	5	GO:0030007
GeneOntologyBiologicalProcess	establishment or maintenance of transmembrane electrochemical gradient	ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.37e-07	11	119	4	GO:0010248
GeneOntologyBiologicalProcess	cell communication by electrical coupling involved in cardiac conduction	RYR2 GJA5 ATP1A1 ATP1A2 ATP1A3	3.51e-07	26	119	5	GO:0086064
GeneOntologyBiologicalProcess	regulation of membrane potential	PLK2 XIRP1 GPR39 TMEM135 GRM1 MFN1 RYR2 GJA5 KCNMA1 MFN2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 MAPK8IP2	8.02e-07	559	119	15	GO:0042391
GeneOntologyBiologicalProcess	cell communication by electrical coupling	RYR2 GJA5 ATP1A1 ATP1A2 ATP1A3	1.66e-06	35	119	5	GO:0010644
GeneOntologyBiologicalProcess	response to glycoside	ATP1A1 ATP1A2 ATP1A3	1.86e-06	5	119	3	GO:1903416
GeneOntologyBiologicalProcess	potassium ion homeostasis	KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.21e-06	37	119	5	GO:0055075
GeneOntologyBiologicalProcess	sodium ion export across plasma membrane	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.37e-06	17	119	4	GO:0036376
GeneOntologyBiologicalProcess	neuron development	TNIK PLXNA3 PRTG FAT4 PLK2 NCKAP1 MYO6 ITSN1 CEP290 RAB6B TNFRSF21 ADCY6 MFN1 PTPN9 DST RNF6 KCNMA1 MFN2 MACF1 CTNNA2 HERC1 RAB6A EPHA10 MAPK8IP2	2.70e-06	1463	119	24	GO:0048666
GeneOntologyBiologicalProcess	neuron projection development	TNIK PLXNA3 PRTG FAT4 PLK2 NCKAP1 MYO6 ITSN1 RAB6B TNFRSF21 ADCY6 MFN1 PTPN9 DST RNF6 MFN2 MACF1 CTNNA2 HERC1 RAB6A EPHA10 MAPK8IP2	3.84e-06	1285	119	22	GO:0031175
GeneOntologyBiologicalProcess	import across plasma membrane	SLC43A2 GRM1 SLC5A3 ACSL1 SLC5A6 ATP1A1 ATP1A2 ATP1A3 ATP1A4	7.62e-06	230	119	9	GO:0098739
GeneOntologyBiologicalProcess	cell communication involved in cardiac conduction	RYR2 GJA5 ATP1A1 ATP1A2 ATP1A3	2.29e-05	59	119	5	GO:0086065
GeneOntologyBiologicalProcess	intracellular sodium ion homeostasis	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.57e-05	30	119	4	GO:0006883
GeneOntologyBiologicalProcess	positive regulation of mitochondrial membrane potential	TMEM135 MFN1 MFN2	9.93e-05	16	119	3	GO:0010918
GeneOntologyBiologicalProcess	regulation of cardiac muscle cell contraction	RYR2 GJA5 ATP1A1 ATP1A2	1.09e-04	43	119	4	GO:0086004
GeneOntologyBiologicalProcess	transport across blood-brain barrier	SLC5A3 SLC5A6 SLC22A3 ATP1A2 ATP1A4	1.49e-04	87	119	5	GO:0150104
GeneOntologyBiologicalProcess	vascular transport	SLC5A3 SLC5A6 SLC22A3 ATP1A2 ATP1A4	1.57e-04	88	119	5	GO:0010232
GeneOntologyBiologicalProcess	vascular process in circulatory system	COMP ADCY6 SLC5A3 GJA5 SLC5A6 SLC22A3 KCNMA1 ATP1A2 ATP1A4	1.74e-04	344	119	9	GO:0003018
GeneOntologyBiologicalProcess	regulation of atrial cardiac muscle cell action potential	RYR2 GJA5	1.97e-04	4	119	2	GO:0098910
GeneOntologyBiologicalProcess	potassium ion import across plasma membrane	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.13e-04	51	119	4	GO:1990573
GeneOntologyBiologicalProcess	sodium ion homeostasis	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.13e-04	51	119	4	GO:0055078
GeneOntologyBiologicalProcess	regulation of actin filament-based movement	RYR2 GJA5 ATP1A1 ATP1A2	2.48e-04	53	119	4	GO:1903115
GeneOntologyBiologicalProcess	cardiac conduction	RYR2 GJA5 ATP1A1 ATP1A2 ATP1A3	2.86e-04	100	119	5	GO:0061337
GeneOntologyBiologicalProcess	protein localization to Golgi membrane	RAB6B RAB6A	3.26e-04	5	119	2	GO:1903292
GeneOntologyBiologicalProcess	regulation of AV node cell action potential	RYR2 GJA5	3.26e-04	5	119	2	GO:0098904
GeneOntologyBiologicalProcess	embryonic heart tube development	NCKAP1 IFT172 RYR2 GJA5 C2CD3	3.28e-04	103	119	5	GO:0035050
GeneOntologyBiologicalProcess	positive regulation of membrane potential	TMEM135 MFN1 MFN2	3.93e-04	25	119	3	GO:0045838
GeneOntologyBiologicalProcess	negative regulation of cytosolic calcium ion concentration	RYR2 GTF2I ATP1A2	3.93e-04	25	119	3	GO:0051481
GeneOntologyBiologicalProcess	proton transmembrane transport	COX15 UQCR10 ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.62e-04	170	119	6	GO:1902600
GeneOntologyBiologicalProcess	Purkinje myocyte to ventricular cardiac muscle cell communication	RYR2 GJA5	4.88e-04	6	119	2	GO:0086068
GeneOntologyBiologicalProcess	Purkinje myocyte to ventricular cardiac muscle cell signaling	RYR2 GJA5	4.88e-04	6	119	2	GO:0086029
GeneOntologyBiologicalProcess	mitochondrion distribution	MFN1 PKD1 MFN2	4.95e-04	27	119	3	GO:0048311
GeneOntologyCellularComponent	sodium:potassium-exchanging ATPase complex	ATP1A1 ATP1A2 ATP1A3 ATP1A4	5.10e-07	12	121	4	GO:0005890
GeneOntologyCellularComponent	basal plasma membrane	SLC43A2 CEACAM8 CR1L SLC5A3 DST SLC5A6 SLC22A3 PKD1 CTNNA2 ATP1A1	4.09e-05	354	121	10	GO:0009925
GeneOntologyCellularComponent	intercalated disc	XIRP1 GJA5 DST ATP1A1 ATP1A2	4.66e-05	68	121	5	GO:0014704
GeneOntologyCellularComponent	basal part of cell	SLC43A2 CEACAM8 CR1L SLC5A3 DST SLC5A6 SLC22A3 PKD1 CTNNA2 ATP1A1	7.08e-05	378	121	10	GO:0045178
GeneOntologyCellularComponent	organelle envelope	MYO6 MRPL55 ITSN1 COX6A1 TMEM135 COX15 MRPL52 UQCR10 IFI27 NDUFV1 MFN1 RYR2 ACSL1 DST RNF6 PMPCA SLC22A3 MFN2 HAAO HERC2 MFSD10	7.19e-05	1435	121	21	GO:0031967
GeneOntologyCellularComponent	basolateral plasma membrane	SLC43A2 CEACAM8 CR1L SLC5A3 SLC5A6 SLC22A3 PKD1 CTNNA2 ATP1A1	1.04e-04	320	121	9	GO:0016323
GeneOntologyCellularComponent	mitochondrial membrane	MRPL55 COX6A1 TMEM135 COX15 MRPL52 UQCR10 IFI27 NDUFV1 MFN1 ACSL1 PMPCA SLC22A3 MFN2 HAAO HERC2	1.45e-04	866	121	15	GO:0031966
GeneOntologyCellularComponent	cation-transporting ATPase complex	ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.85e-04	49	121	4	GO:0090533
GeneOntologyCellularComponent	photoreceptor inner segment membrane	ATP1A1 ATP1A3	1.98e-04	4	121	2	GO:0060342
GeneOntologyCellularComponent	cell-cell contact zone	XIRP1 GJA5 DST ATP1A1 ATP1A2	2.18e-04	94	121	5	GO:0044291
GeneOntologyCellularComponent	neuron to neuron synapse	TNIK MYO6 CHD4 GRM1 DST MACF1 CTNNA2 ATP1A1 ATP1A3 MAPK8IP2 KLHL17	2.32e-04	523	121	11	GO:0098984
GeneOntologyCellularComponent	transmembrane transporter complex	COX6A1 UQCR10 NDUFV1 RYR2 SLC5A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.32e-04	523	121	11	GO:1902495
GeneOntologyCellularComponent	mitochondrial envelope	MRPL55 COX6A1 TMEM135 COX15 MRPL52 UQCR10 IFI27 NDUFV1 MFN1 ACSL1 PMPCA SLC22A3 MFN2 HAAO HERC2	2.54e-04	912	121	15	GO:0005740
GeneOntologyCellularComponent	ATPase dependent transmembrane transport complex	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.90e-04	55	121	4	GO:0098533
GeneOntologyCellularComponent	transporter complex	COX6A1 UQCR10 NDUFV1 RYR2 SLC5A3 PKD1 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.56e-04	550	121	11	GO:1990351
GeneOntologyCellularComponent	asymmetric synapse	TNIK MYO6 CHD4 GRM1 DST MACF1 CTNNA2 ATP1A1 MAPK8IP2 KLHL17	4.61e-04	477	121	10	GO:0032279
GeneOntologyCellularComponent	mitochondrial protein-containing complex	MRPL55 COX6A1 COX15 MRPL52 UQCR10 MFN1 PMPCA	6.39e-04	250	121	7	GO:0098798
GeneOntologyCellularComponent	apical part of cell	TNIK FAT4 MYO6 CEACAM8 CYP4A22 SLC5A3 SLC5A6 SLC22A3 KCNMA1 UPK2 ATP1A1	6.57e-04	592	121	11	GO:0045177
GeneOntologyCellularComponent	postsynapse	TNIK NCKAP1 MYO6 ITSN1 NBEA GRM1 DST KCNMA1 MACF1 CTNNA2 ATP1A1 ATP1A2 ATP1A3 MAPK8IP2 KLHL17	7.99e-04	1018	121	15	GO:0098794
GeneOntologyCellularComponent	sarcolemma	ADCY6 RYR2 DST ATP1A1 ATP1A2 ATP1A3	8.43e-04	190	121	6	GO:0042383
GeneOntologyCellularComponent	rod photoreceptor outer segment	CEP290 ATP1A4	1.16e-03	9	121	2	GO:0120200
GeneOntologyCellularComponent	postsynaptic density	TNIK MYO6 GRM1 DST MACF1 CTNNA2 ATP1A1 MAPK8IP2 KLHL17	1.26e-03	451	121	9	GO:0014069
GeneOntologyCellularComponent	organelle inner membrane	MRPL55 COX6A1 COX15 MRPL52 UQCR10 IFI27 NDUFV1 MFN1 PMPCA HERC2 MFSD10	1.43e-03	652	121	11	GO:0019866
GeneOntologyCellularComponent	actin cytoskeleton	XIRP1 NCKAP1 MYO6 ITSN1 MYOZ3 KLHL20 DST MACF1 CTNNA2 KLHL17	1.92e-03	576	121	10	GO:0015629
GeneOntologyCellularComponent	axon	PRTG HDAC5 MYO6 ITSN1 GRM1 TNFRSF21 KLHL20 DST RNF6 KCNMA1 CTNNA2 ATP1A1 ATP1A3	1.97e-03	891	121	13	GO:0030424
GeneOntologyCellularComponent	cytochrome complex	COX6A1 COX15 UQCR10	2.11e-03	44	121	3	GO:0070069
GeneOntologyCellularComponent	apical plasma membrane	TNIK CEACAM8 CYP4A22 SLC5A3 SLC5A6 SLC22A3 KCNMA1 UPK2 ATP1A1	2.12e-03	487	121	9	GO:0016324
GeneOntologyCellularComponent	membrane protein complex	COX6A1 CEACAM8 COX15 GRM1 UQCR10 NDUFV1 MFN1 RYR2 SLC5A3 GJA5 SEC24C PKD1 KCNMA1 CTNNA2 ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.43e-03	1498	121	18	GO:0098796
GeneOntologyCellularComponent	peroxisome	IMPDH2 LONP2 TMEM135 ACSL1 EHHADH	2.54e-03	162	121	5	GO:0005777
GeneOntologyCellularComponent	microbody	IMPDH2 LONP2 TMEM135 ACSL1 EHHADH	2.54e-03	162	121	5	GO:0042579
GeneOntologyCellularComponent	postsynaptic specialization	TNIK MYO6 GRM1 DST MACF1 CTNNA2 ATP1A1 MAPK8IP2 KLHL17	2.63e-03	503	121	9	GO:0099572
MousePheno	abnormal amniotic fluid composition	SLC43A2 SLC5A3 PKD1	1.88e-05	8	99	3	MP:0012172
Domain	P-type_ATPase_IIC	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.33e-08	6	119	4	IPR005775
Domain	ATPase_P-typ_TM_dom	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.69e-06	16	119	4	IPR023298
Domain	-	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.69e-06	16	119	4	1.20.1110.10
Domain	ATPase_P-typ_cation-transptr_C	ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.50e-06	17	119	4	IPR006068
Domain	Cation_ATPase_C	ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.50e-06	17	119	4	PF00689
Domain	Cation_ATPase_N	ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.47e-06	18	119	4	PF00690
Domain	Cation_ATPase_N	ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.47e-06	18	119	4	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP1A1 ATP1A2 ATP1A3 ATP1A4	5.64e-06	19	119	4	IPR004014
Domain	Fzo_mitofusin	MFN1 MFN2	4.03e-05	2	119	2	PF04799
Domain	Mitofusin_fam	MFN1 MFN2	4.03e-05	2	119	2	IPR027094
Domain	Fzo/mitofusin_HR2	MFN1 MFN2	4.03e-05	2	119	2	IPR006884
Domain	-	ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.91e-05	32	119	4	3.40.1110.10
Domain	-	ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.91e-05	32	119	4	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP1A1 ATP1A2 ATP1A3 ATP1A4	7.04e-05	35	119	4	IPR023299
Domain	ATPase_P-typ_P_site	ATP1A1 ATP1A2 ATP1A3 ATP1A4	7.88e-05	36	119	4	IPR018303
Domain	P_typ_ATPase	ATP1A1 ATP1A2 ATP1A3 ATP1A4	7.88e-05	36	119	4	IPR001757
Domain	ATPASE_E1_E2	ATP1A1 ATP1A2 ATP1A3 ATP1A4	7.88e-05	36	119	4	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP1A1 ATP1A2 ATP1A3 ATP1A4	8.79e-05	37	119	4	IPR008250
Domain	E1-E2_ATPase	ATP1A1 ATP1A2 ATP1A3 ATP1A4	8.79e-05	37	119	4	PF00122
Domain	COMP	COMP THBS3	1.20e-04	3	119	2	PF11598
Domain	Thbs/COMP_coiled-coil	COMP THBS3	1.20e-04	3	119	2	IPR024665
Domain	TSP_3	COMP THBS3	3.98e-04	5	119	2	PF02412
Domain	TSP3	COMP THBS3	3.98e-04	5	119	2	PS51234
Domain	TSP_CTER	COMP THBS3	3.98e-04	5	119	2	PS51236
Domain	Thrombospondin_3_rpt	COMP THBS3	3.98e-04	5	119	2	IPR017897
Domain	TSP_type-3_rpt	COMP THBS3	3.98e-04	5	119	2	IPR028974
Domain	-	COMP THBS3	3.98e-04	5	119	2	4.10.1080.10
Domain	Thrombospondin_C	COMP THBS3	3.98e-04	5	119	2	IPR008859
Domain	TSP_C	COMP THBS3	3.98e-04	5	119	2	PF05735
Domain	Thrombospondin_3-like_rpt	COMP THBS3	3.98e-04	5	119	2	IPR003367
Domain	ConA-like_dom	FAT4 COMP NBEA DDX1 RYR2 THBS3 HERC1	5.11e-04	219	119	7	IPR013320
Domain	EFh	ITSN1 CAPNS1 EFHB RYR2 DST MACF1	5.27e-04	158	119	6	SM00054
Domain	-	DST MACF1	5.94e-04	6	119	2	3.90.1290.10
Domain	GAR	DST MACF1	5.94e-04	6	119	2	PS51460
Domain	GAS2	DST MACF1	5.94e-04	6	119	2	PF02187
Domain	-	DST MACF1	5.94e-04	6	119	2	3.30.920.20
Domain	GAS_dom	DST MACF1	5.94e-04	6	119	2	IPR003108
Domain	GAS2	DST MACF1	5.94e-04	6	119	2	SM00243
Domain	Plectin	DST MACF1	8.28e-04	7	119	2	PF00681
Domain	Plectin_repeat	DST MACF1	8.28e-04	7	119	2	IPR001101
Domain	PLEC	DST MACF1	8.28e-04	7	119	2	SM00250
Domain	Na/solute_symporter_CS	SLC5A3 SLC5A6	1.10e-03	8	119	2	IPR018212
Domain	-	ITSN1 CAPNS1 RHBDL1 EFHB RYR2 DST MACF1	1.42e-03	261	119	7	1.10.238.10
Domain	HAD-like_dom	ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.63e-03	79	119	4	IPR023214
Domain	MIR	POMT2 RYR2	1.75e-03	10	119	2	PF02815
Domain	MIR_motif	POMT2 RYR2	1.75e-03	10	119	2	IPR016093
Domain	MIR	POMT2 RYR2	1.75e-03	10	119	2	PS50919
Domain	MIR	POMT2 RYR2	1.75e-03	10	119	2	SM00472
Domain	GDS_CDC24_CS	ITSN1 PLEKHG1 VAV2	1.95e-03	39	119	3	IPR001331
Domain	NA_SOLUT_SYMP_1	SLC5A3 SLC5A6	2.13e-03	11	119	2	PS00456
Domain	EF-hand-dom_pair	ITSN1 CAPNS1 RHBDL1 EFHB RYR2 DST MACF1	2.44e-03	287	119	7	IPR011992
Domain	SSF	SLC5A3 SLC5A6	2.55e-03	12	119	2	PF00474
Domain	NA_SOLUT_SYMP_2	SLC5A3 SLC5A6	2.55e-03	12	119	2	PS00457
Domain	Na/solute_symporter	SLC5A3 SLC5A6	2.55e-03	12	119	2	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A3 SLC5A6	2.55e-03	12	119	2	PS50283
Domain	SH3	DOCK3 ITSN1 DST MACF1 VAV2 MAPK8IP2	2.62e-03	216	119	6	PS50002
Domain	SH3_domain	DOCK3 ITSN1 DST MACF1 VAV2 MAPK8IP2	2.87e-03	220	119	6	IPR001452
Domain	EF-hand_1	CAPNS1 EFHB RYR2 DST MACF1	2.90e-03	152	119	5	PF00036
Domain	-	FAT4 COMP NBEA THBS3	3.19e-03	95	119	4	2.60.120.200
Domain	-	POLD1 PIWIL2 NYNRIN	3.33e-03	47	119	3	3.30.420.10
Domain	G_DYNAMIN_dom	MFN1 MFN2	3.48e-03	14	119	2	IPR030381
Domain	G_DYNAMIN_2	MFN1 MFN2	3.48e-03	14	119	2	PS51718
Domain	EF_HAND_2	ITSN1 CAPNS1 EFHB RYR2 DST MACF1	3.65e-03	231	119	6	PS50222
Domain	EF_hand_dom	ITSN1 CAPNS1 EFHB RYR2 DST MACF1	3.73e-03	232	119	6	IPR002048
Domain	Dynamin_GTPase	MFN1 MFN2	4.00e-03	15	119	2	IPR001401
Domain	Dynamin_SF	MFN1 MFN2	4.00e-03	15	119	2	IPR022812
Domain	Dynamin_N	MFN1 MFN2	4.00e-03	15	119	2	PF00350
Domain	EF_Hand_1_Ca_BS	ITSN1 CAPNS1 EFHB DST MACF1	5.28e-03	175	119	5	IPR018247
Domain	Gal_Oxase/kelch_b-propeller	LCMT2 KLHL20 KLHL17	6.33e-03	59	119	3	IPR011043
Pathway	KEGG_CARDIAC_MUSCLE_CONTRACTION	COX6A1 UQCR10 RYR2 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.40e-06	79	100	7	M17673
Pathway	KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION	ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.90e-05	23	100	4	M4361
Pathway	REACTOME_ION_HOMEOSTASIS	RYR2 ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.90e-05	54	100	5	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	RYR2 ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.90e-05	54	100	5	MM15202
Pathway	KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.17e-04	42	100	4	M16473
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.39e-10	4	121	4	21849490
Pubmed	Multiple genes encode the human Na+,K+-ATPase catalytic subunit.	ATP1A1 ATP1A2 ATP1A3 ATP1A4	6.95e-10	5	121	4	3035563
Pubmed	The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.	ATP1A1 ATP1A2 ATP1A3 ATP1A4	2.08e-09	6	121	4	3036582
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	TNIK NCKAP1 MYO6 KDM5C UQCR10 RAB6B ADCY6 NDUFV1 ACSL1 DST EHHADH MFN2 ATP1A1 ATP1A4 RAB6A	4.78e-09	621	121	15	22794259
Pubmed	Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.	ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.84e-09	7	121	4	10837135
Pubmed	Molecular genetics of Na,K-ATPase.	ATP1A1 ATP1A2 ATP1A3 ATP1A4	4.84e-09	7	121	4	2158121
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 PLXNA3 TPRA1 MRPL55 COX6A1 TMCO6 ANKHD1 TNFRSF21 BAP1 PLEKHG1 C2CD3 DST PKD1 CPSF1 MFN2 HERC2 HERC1 KLHL17 RASD2	9.61e-09	1105	121	19	35748872
Pubmed	Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	2822726
Pubmed	Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	30819023
Pubmed	Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.	ATP1A1 ATP1A3 ATP1A4	4.11e-08	3	121	3	26373354
Pubmed	Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	17947306
Pubmed	Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	19058785
Pubmed	Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	28465228
Pubmed	Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	8203495
Pubmed	Na,K-ATPase and the role of alpha isoforms in behavior.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	18044013
Pubmed	Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	26911348
Pubmed	Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.	ATP1A1 ATP1A2 ATP1A3	4.11e-08	3	121	3	25994790
Pubmed	The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.	CHD4 NDUFV1 MFN1 ACSL1 GJA5 MFN2	7.43e-08	61	121	6	27166947
Pubmed	Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.	ATP1A1 ATP1A2 ATP1A3	1.64e-07	4	121	3	21731499
Pubmed	The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.	ATP1A1 ATP1A2 ATP1A3	1.64e-07	4	121	3	12458206
Pubmed	Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.	ATP1A1 ATP1A2 ATP1A3	1.64e-07	4	121	3	17446412
Pubmed	Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.	ATP1A1 ATP1A2 ATP1A3	1.64e-07	4	121	3	19751721
Pubmed	Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.	ATP1A1 ATP1A2 ATP1A3	1.64e-07	4	121	3	19376779
Pubmed	Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.	ATP1A1 ATP1A2 ATP1A3	1.64e-07	4	121	3	17234593
Pubmed	Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.	ATP1A1 ATP1A3 ATP1A4	1.64e-07	4	121	3	2887455
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK IMPDH2 NCKAP1 ITSN1 NBEA CHD4 GRM1 PTPN9 DST SEC24C KCNMA1 MFN2 MACF1 CTNNA2 HERC2 MAPK8IP2	2.50e-07	963	121	16	28671696
Pubmed	Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.	ATP1A1 ATP1A2 ATP1A3	8.15e-07	6	121	3	10636900
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	SLC43A2 CAPNS1 GRM1 PPM1J NDUFV1 PTPN9 DST SLC5A6 PKD1 ATP1A1 HERC2 MFSD10 YIPF3	1.02e-06	697	121	13	28298427
Pubmed	Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.	NCKAP1 KCNMA1 ATP1A1 ATP1A2 ATP1A3	1.07e-06	52	121	5	20114047
Pubmed	Expression and distribution of Na, K-ATPase isoforms in the human uterus.	ATP1A1 ATP1A2 ATP1A3	1.42e-06	7	121	3	20065300
Pubmed	Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.	ATP1A1 ATP1A2 ATP1A3	2.27e-06	8	121	3	19683723
Pubmed	Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.	ATP1A1 ATP1A2 ATP1A3	2.27e-06	8	121	3	2885848
Pubmed	Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.	ATP1A1 ATP1A2 ATP1A3	2.27e-06	8	121	3	23652595
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TNIK DOCK3 PCDHA9 POLD1 NBEA RAB6B GSTZ1 SLC22A3 PKD1	2.43e-06	329	121	9	17474147
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	POMT2 MRPL55 TMCO6 MRPL52 CHD4 EFHB RAB6B DDX1 GTF2I MACF1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 LSM8 RAB6A	2.63e-06	1153	121	16	29845934
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP1A1 ATP1A2 ATP1A3 ATP1A4	3.09e-06	29	121	4	15071553
Pubmed	The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.	ATP1A1 ATP1A2 ATP1A3	3.40e-06	9	121	3	15253893
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	MYO6 KCNMA1 CTNNA2 ATP1A1 ATP1A2 ATP1A3	6.86e-06	131	121	6	28634551
Pubmed	Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.	ATP1A1 ATP1A2 ATP1A3	8.83e-06	12	121	3	27097562
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CCDC170 FAT4 ITSN1 CEP290 NBEA PIWIL2 ZNF831 DST RDH16 MOGS PKD1 CPSF1	1.05e-05	736	121	12	29676528
Pubmed	Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.	COX6A1 NDUFV1 MFN2 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.09e-05	215	121	7	36808153
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TNIK MARS2 IMPDH2 NCKAP1 ANKHD1 UQCR10 NDUFV1 DST SEC24C MOGS MFN2 MACF1 BSCL2 CTNNA2 ATP1A1 RAB6A	1.15e-05	1297	121	16	33545068
Pubmed	Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.	MFN1 MFN2	1.20e-05	2	121	2	24074867
Pubmed	Tolvaptan plus pasireotide shows enhanced efficacy in a PKD1 model.	ADCY6 PKD1	1.20e-05	2	121	2	24994926
Pubmed	Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance.	ATP1A1 ATP1A2	1.20e-05	2	121	2	15781423
Pubmed	Adenylyl cyclase 6 deficiency ameliorates polycystic kidney disease.	ADCY6 PKD1	1.20e-05	2	121	2	24158982
Pubmed	Mfn2 is critical for brown adipose tissue thermogenic function.	MFN1 MFN2	1.20e-05	2	121	2	28348166
Pubmed	Mitofusin1 in oocyte is essential for female fertility.	MFN1 MFN2	1.20e-05	2	121	2	30690319
Pubmed	Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells.	MFN1 MFN2	1.20e-05	2	121	2	31431479
Pubmed	Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.	MFN1 MFN2	1.20e-05	2	121	2	30882371
Pubmed	The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue.	MFN1 MFN2	1.20e-05	2	121	2	34600274
Pubmed	A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space.	MFN1 MFN2	1.20e-05	2	121	2	29212658
Pubmed	Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.	ATP1A1 ATP1A3	1.20e-05	2	121	2	21498719
Pubmed	Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations.	MFN1 MFN2	1.20e-05	2	121	2	17296794
Pubmed	Mitofusin 1 is required for oocyte growth and communication with follicular somatic cells.	MFN1 MFN2	1.20e-05	2	121	2	32281181
Pubmed	Molecular cloning of the mouse ouabain-resistance gene.	ATP1A1 ATP1A2	1.20e-05	2	121	2	6324196
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.20e-05	2	121	2	11002341
Pubmed	Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.	ATP1A1 ATP1A2	1.20e-05	2	121	2	19376809
Pubmed	MFN1 and MFN2 Are Dispensable for Sperm Development and Functions in Mice.	MFN1 MFN2	1.20e-05	2	121	2	34948301
Pubmed	A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase.	ATP1A1 ATP1A2	1.20e-05	2	121	2	35446892
Pubmed	Mitochondrial Dynamics in Tachycardiomyopathy.	MFN1 MFN2	1.20e-05	2	121	2	30873819
Pubmed	New molecular determinants controlling the accessibility of ouabain to its binding site in human Na,K-ATPase alpha isoforms.	ATP1A1 ATP1A2	1.20e-05	2	121	2	14742675
Pubmed	ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.	ATP1A2 ATP1A3	1.20e-05	2	121	2	33880529
Pubmed	MFN2 interacts with nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis.	MFN1 MFN2	1.20e-05	2	121	2	33674260
Pubmed	Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation.	RAB6B RAB6A	1.20e-05	2	121	2	38830762
Pubmed	The alpha(1)- and alpha(2)-isoforms of Na-K-ATPase play different roles in skeletal muscle contractility.	ATP1A1 ATP1A2	1.20e-05	2	121	2	11507009
Pubmed	Loss of mitofusin 2 promotes endoplasmic reticulum stress.	MFN1 MFN2	1.20e-05	2	121	2	22511781
Pubmed	The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.	ATP1A2 ATP1A4	1.20e-05	2	121	2	10555956
Pubmed	The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.	ATP1A2 ATP1A3	1.20e-05	2	121	2	18957371
Pubmed	All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.	ATP1A1 ATP1A3	1.20e-05	2	121	2	11546672
Pubmed	Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.	ATP1A1 ATP1A3	1.20e-05	2	121	2	24391932
Pubmed	Mitofusin 2 tethers endoplasmic reticulum to mitochondria.	MFN1 MFN2	1.20e-05	2	121	2	19052620
Pubmed	RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.	STK4 RNF6	1.20e-05	2	121	2	34970341
Pubmed	DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.	ATP1A1 ATP1A2	1.20e-05	2	121	2	22258333
Pubmed	The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion.	MFN1 MFN2	1.20e-05	2	121	2	29661855
Pubmed	Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation.	MFN1 MFN2	1.20e-05	2	121	2	27404125
Pubmed	Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.	ATP1A1 ATP1A2	1.20e-05	2	121	2	22739122
Pubmed	Mitofusin 1 overexpression rescues the abnormal mitochondrial dynamics caused by the Mitofusin 2 K357T mutation in vitro.	MFN1 MFN2	1.20e-05	2	121	2	37220142
Pubmed	Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart.	ATP1A1 ATP1A2	1.20e-05	2	121	2	10360172
Pubmed	Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.	ATP1A1 ATP1A3	1.20e-05	2	121	2	23761886
Pubmed	A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion.	MFN1 MFN2	1.20e-05	2	121	2	30936207
Pubmed	Adult skeletal muscle deletion of Mitofusin 1 and 2 impedes exercise performance and training capacity.	MFN1 MFN2	1.20e-05	2	121	2	30260752
Pubmed	Dopamine receptor antagonists as potential therapeutic agents for ADPKD.	HDAC5 PKD1	1.20e-05	2	121	2	31059522
Pubmed	Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells.	MFN1 MFN2	1.20e-05	2	121	2	21839087
Pubmed	Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.	ATP1A1 ATP1A2	1.20e-05	2	121	2	11404365
Pubmed	Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy.	ATP1A1 ATP1A2	1.20e-05	2	121	2	20952666
Pubmed	The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.	ATP1A1 ATP1A3	1.20e-05	2	121	2	3030810
Pubmed	Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.	ATP1A1 ATP1A2	1.20e-05	2	121	2	18667729
Pubmed	Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site.	ATP1A1 ATP1A2	1.20e-05	2	121	2	21632957
Pubmed	Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.	MFN1 MFN2	1.20e-05	2	121	2	22777004
Pubmed	Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.	ATP1A2 ATP1A3	1.20e-05	2	121	2	24356962
Pubmed	Structural basis of mitochondrial tethering by mitofusin complexes.	MFN1 MFN2	1.20e-05	2	121	2	15297672
Pubmed	Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia.	RYR2 GJA5	1.20e-05	2	121	2	27169737
Pubmed	Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells.	MFN1 MFN2	1.20e-05	2	121	2	12759376
Pubmed	Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo.	MFN1 MFN2	1.20e-05	2	121	2	11950885
Pubmed	Expression of alpha isoforms of the Na,K-ATPase in human heart.	ATP1A1 ATP1A2	1.20e-05	2	121	2	8391840
Pubmed	MFN2 Plays a Distinct Role from MFN1 in Regulating Spermatogonial Differentiation.	MFN1 MFN2	1.20e-05	2	121	2	32330448
Pubmed	Control of mitochondrial morphology by a human mitofusin.	MFN1 MFN2	1.20e-05	2	121	2	11181170
Pubmed	Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease.	MFN1 MFN2	1.20e-05	2	121	2	24710686
Pubmed	Evaluation of the role of mitofusin-1 and mitofusin-2 in periodontal disease.	MFN1 MFN2	1.20e-05	2	121	2	37436713
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.36e-08	7	82	4	1208
GeneFamily	EF-hand domain containing	ITSN1 CAPNS1 EFHB RYR2 DST MACF1	4.80e-04	219	82	6	863
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	5.59e-04	8	82	2	939
ToppCell	droplet-Kidney-nan-3m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 MYO6 COX6A1 UQCR10 NDUFV1 SLC5A3 ACSL1 DST ATP1A1	3.49e-09	196	121	9	9f39cb3de886283da34ee7511a92d94930a6c851
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 MYO6 NBEA CHD4 DST MACF1 HERC1 MAPK8IP2	6.38e-08	195	121	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Kidney-nan-3m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX6A1 UQCR10 SLC5A3 ACSL1 DST ATP1A1 MAPK8IP2	8.40e-07	188	121	7	6b185d0aaeea64f9ae584a9bcb9741658bb1c7bd
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DOCK3 NBEA RAB6B GPR61 HERC1 ATP1A3 MAPK8IP2	1.00e-06	193	121	7	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 NBEA RAB6B F12 CTNNA2 ATP1A3 MAPK8IP2	1.07e-06	195	121	7	5a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCell	droplet-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 MYO6 COX6A1 UQCR10 SLC5A3 DST ATP1A1	1.11e-06	196	121	7	b880c9665d42c76ea1971d4e49d7ecf72fcfafb6
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COMP MYOZ3 UCMA KCNMA1 CTNNA2 ATP1A4	6.46e-06	167	121	6	102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GALNT15 FAT4 COMP DST MACF1 ATP1A2	8.43e-06	175	121	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	KDM5C ANKHD1 PPM1J MFN1 DST SEC24C	8.71e-06	176	121	6	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NCKAP1 ANKHD1 ZNF831 GPKOW SLC5A6 KLHL17	9.00e-06	177	121	6	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	facs-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX6A1 UQCR10 ACSL1 GSTZ1 RDH16 EHHADH	9.00e-06	177	121	6	7f58286fc8797e9bdcf8ece0849f55680905955d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GALNT15 FAT4 COMP RYR2 DST ATP1A2	1.02e-05	181	121	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK MYO6 CHD4 PPM1J SLC22A3 MACF1	1.05e-05	182	121	6	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK MYO6 CHD4 PPM1J SLC22A3 MACF1	1.05e-05	182	121	6	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UQCR10 SLC5A3 ACSL1 DST ATP1A1 MAPK8IP2	1.09e-05	183	121	6	6b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 SLC35F1 GRM1 RYR2 ATP1A4 EPHA10	1.12e-05	184	121	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK DOCK3 RYR2 PLEKHG1 DST MACF1	1.12e-05	184	121	6	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 SLC35F1 GRM1 RYR2 ATP1A4 EPHA10	1.12e-05	184	121	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 SLC35F1 GRM1 RYR2 ATP1A4 EPHA10	1.12e-05	184	121	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 ADCY6 SLC5A3 PLEKHG1 DST ATP1A1	1.16e-05	185	121	6	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	facs-Kidney-nan-3m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX6A1 UQCR10 SLC5A3 ACSL1 DST ATP1A1	1.23e-05	187	121	6	208686e6ebc9f3a774bcbe89274457ac9449f90e
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 ADCY6 MFN1 RYR2 NYNRIN KCNMA1	1.27e-05	188	121	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 ADCY6 MFN1 RYR2 NYNRIN KCNMA1	1.27e-05	188	121	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 ADCY6 MFN1 RYR2 NYNRIN KCNMA1	1.27e-05	188	121	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RAB6B RYR2 GPR61 ATP1A3 EPHA10 MAPK8IP2	1.35e-05	190	121	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO6 NBEA CHD4 DST MACF1 HERC1	1.56e-05	195	121	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	POMT2 GALNT10 DDX60 MYOZ3 MACF1 HERC1	1.70e-05	198	121	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKAP1 MYO6 CHTF8 DST BSCL2 ATP1A1	1.70e-05	198	121	6	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCKAP1 MYO6 CHTF8 DST BSCL2 ATP1A1	1.70e-05	198	121	6	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	DOCK3 NBEA RAB6B ATP1A3 RAB6A MAPK8IP2	1.75e-05	199	121	6	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 COX6A1 NDUFV1 SLC5A3 ACSL1 ATP1A1	1.80e-05	200	121	6	4bbb35d43d238fdd173fe2557cb31d2b56f767b5
ToppCell	Hippocampus-Macroglia-CSF_related\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCDC170 EFHB HAAO UPK2 TTLL10	5.98e-05	152	121	5	c2b6cc41546cbd46b9ea5d28a7c66f6330a27df2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT15 MYOZ3 PLEKHG1 GJA5 GPR61	6.36e-05	154	121	5	e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COX15 IFI27 RNF6 NYNRIN SLC5A6	6.96e-05	157	121	5	abfd05ed993b80822739f47a735f154092a23632
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NDUFV1 KLHL20 SLC5A6 KCNMA1 HAAO	8.08e-05	162	121	5	10f7de4fb40ea9aee89bde3a280a82f6ccba2aeb
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	ANKHD1 ZNF831 GPKOW SLC5A6 KLHL17	1.10e-04	173	121	5	e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell	LV-11._Adipocyte\|LV / Chamber and Cluster_Paper	ITSN1 CEACAM8 ACSL1 EEPD1 SLC22A3	1.10e-04	173	121	5	c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	KDM5C ANKHD1 MFN1 DST SEC24C	1.13e-04	174	121	5	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MARS2 GJA5 C2CD3 DST RASD2	1.16e-04	175	121	5	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	facs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC170 TNFRSF21 GSTZ1 EHHADH SLC5A6	1.16e-04	175	121	5	076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCell	facs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC170 TNFRSF21 GSTZ1 EHHADH SLC5A6	1.16e-04	175	121	5	445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	MARS2 GJA5 C2CD3 DST RASD2	1.16e-04	175	121	5	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	AT1-AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	DOCK3 GALNT10 PCDHA9 IFI27 DST	1.19e-04	176	121	5	f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	ITSN1 CEACAM8 ACSL1 EEPD1 SLC22A3	1.22e-04	177	121	5	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	ITSN1 CEACAM8 ACSL1 EEPD1 SLC22A3	1.26e-04	178	121	5	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	droplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK MYO6 PPM1J SLC22A3 MACF1	1.26e-04	178	121	5	8aef208b6351143562c87715bb11628880abce94
ToppCell	droplet-Kidney-nan-18m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COX6A1 UQCR10 SLC5A3 ACSL1 ATP1A1	1.32e-04	180	121	5	cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A3 DST MFN2 ATP1A1 MAPK8IP2	1.32e-04	180	121	5	0b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NCKAP1 ZNF831 GPKOW SLC5A6 KLHL17	1.32e-04	180	121	5	a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COX6A1 UQCR10 SLC5A3 ACSL1 ATP1A1	1.32e-04	180	121	5	40f79b4455dbd1c2720dc32d9d77c70f835cecb3
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK PLK2 NCKAP1 PLEKHG1 NYNRIN	1.36e-04	181	121	5	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT15 PLK2 NBEA NYNRIN ATP1A4	1.39e-04	182	121	5	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1J NDUFV1 MFN1 RYR2 ACSL1	1.39e-04	182	121	5	c4a7007c864a9455a7e7447e28ccd380878a6a0f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 DST EEPD1 KCNMA1 ATP1A1	1.39e-04	182	121	5	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1J NDUFV1 MFN1 RYR2 ACSL1	1.39e-04	182	121	5	c315d820ffad912c014ba5eac6f5fa6de1a94384
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 NBEA CTNNA2 ATP1A3 MAPK8IP2	1.39e-04	182	121	5	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POLD1 PPM1J IFI35 SLC5A6 HAAO	1.39e-04	182	121	5	b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT15 PLK2 NBEA NYNRIN ATP1A4	1.39e-04	182	121	5	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK PLK2 NCKAP1 PLEKHG1 NYNRIN	1.43e-04	183	121	5	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK PLK2 NCKAP1 PLEKHG1 NYNRIN	1.43e-04	183	121	5	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	TMEM135 ZNF831 ACSL1 EHHADH SLC22A3	1.43e-04	183	121	5	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK GALNT10 PPM1J GTF2I ATP1A1	1.47e-04	184	121	5	c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM1 RYR2 UCMA KCNMA1 ATP1A3	1.51e-04	185	121	5	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 NBEA F12 CTNNA2 MAPK8IP2	1.51e-04	185	121	5	110d5f02759c8235b14aea524ea47199696094ea
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 GRM1 RYR2 GJA5 SLC22A3	1.54e-04	186	121	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 SLC5A3 ACSL1 DST ATP1A1	1.54e-04	186	121	5	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 GRM1 RYR2 GJA5 SLC22A3	1.54e-04	186	121	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 MYO6 DST KCNMA1 ATP1A1	1.58e-04	187	121	5	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	KDM5C ITSN1 LCMT2 HAAO YIPF3	1.58e-04	187	121	5	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 MYO6 DST KCNMA1 ATP1A1	1.58e-04	187	121	5	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 MYO6 DST KCNMA1 ATP1A1	1.58e-04	187	121	5	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO6 DST EEPD1 KCNMA1 ATP1A1	1.58e-04	187	121	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	ITSN1 TMEM135 CEACAM8 ACSL1 SLC22A3	1.62e-04	188	121	5	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	XIRP1 LCMT2 RYR2 SLC22A3 RASD2	1.62e-04	188	121	5	a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 ADCY6 SLC5A3 DST ATP1A1	1.62e-04	188	121	5	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC35F1 RYR2 KCNMA1 ATP1A2 RASD2	1.66e-04	189	121	5	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 ADCY6 SLC5A3 DST ATP1A1	1.66e-04	189	121	5	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	Control\|World / Disease state, Lineage and Cell class	SLC43A2 ACSL1 EEPD1 KCNMA1 MXD1	1.66e-04	189	121	5	fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC170 POMT2 EFHB UCMA TTLL10	1.66e-04	189	121	5	b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC35F1 RYR2 DST SLC22A3 KCNMA1	1.70e-04	190	121	5	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB6B SLC5A3 ACSL1 DST ATP1A1	1.70e-04	190	121	5	c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	GALNT15 FAT4 IFI27 PLEKHG1 GJA5	1.70e-04	190	121	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC35F1 RYR2 DST SLC22A3 KCNMA1	1.70e-04	190	121	5	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC35F1 RYR2 KCNMA1 ATP1A2 RASD2	1.70e-04	190	121	5	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB6B SLC5A3 ACSL1 DST ATP1A1	1.70e-04	190	121	5	5cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 LCMT2 RYR2 SLC22A3 ATP1A2	1.75e-04	191	121	5	8e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 SLC35F1 RYR2 KCNMA1 ATP1A2	1.75e-04	191	121	5	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 SLC35F1 RYR2 KCNMA1 ATP1A2	1.75e-04	191	121	5	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO6 DDX60 IFI27 PLEKHG1 EEPD1	1.79e-04	192	121	5	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM1 RYR2 ACSL1 SLC22A3 MFN2	1.79e-04	192	121	5	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 SLC35F1 RYR2 KCNMA1 ATP1A2	1.79e-04	192	121	5	992d08092edbc68c47b945deb8708379738c239a
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IMPDH2 CHTF8 GTF2I MOGS SLC22A3	1.79e-04	192	121	5	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	IPF-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	TNIK GALNT10 MYO6 PLEKHG1 SLC22A3	1.79e-04	192	121	5	356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM1 RYR2 ACSL1 SLC22A3 MFN2	1.79e-04	192	121	5	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	KDM5C CHD4 PLEKHG1 PMPCA VAV2	1.83e-04	193	121	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 MYO6 IFI27 PLEKHG1 EEPD1	1.83e-04	193	121	5	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 PLK2 STK4 PLEKHG1 EEPD1	1.83e-04	193	121	5	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 PLK2 STK4 PLEKHG1 EEPD1	1.83e-04	193	121	5	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 MYO6 IFI27 PLEKHG1 EEPD1	1.83e-04	193	121	5	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	facs-Bladder-nan-3m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LONP2 CAPNS1 UQCR10 TNFRSF21 CHTF8	1.88e-04	194	121	5	e74cd8cf3763f6adbfd1c269a886a806049714cf
Drug	22,23-dihydrobufalin	ATP1A1 ATP1A2 ATP1A3	1.45e-06	5	121	3	CID000195392
Drug	thevetin A	ATP1A1 ATP1A2 ATP1A3	1.45e-06	5	121	3	CID000441873
Drug	3-acetylstrophanthin	ATP1A1 ATP1A2 ATP1A3	1.45e-06	5	121	3	CID003082282
Drug	ETH157	ATP1A1 ATP1A2 ATP1A3	2.89e-06	6	121	3	CID000563154
Drug	dihydrodigitoxigenin	ATP1A1 ATP1A2 ATP1A3	5.05e-06	7	121	3	CID000107549
Drug	etridiazole	MYO6 RYR2 GJA5 KCNMA1 MAPK8IP2	6.83e-06	50	121	5	CID000017432
Drug	Azides	MFN1 SLC5A6 MFN2	1.20e-05	9	121	3	ctd:D001386
Drug	SCE-129	MYOZ3 NBEA GRM1 NDUFV1 CPSF1 MACF1 HERC2	2.03e-05	156	121	7	CID000002648
Drug	ouabagenin	ATP1A1 ATP1A2 ATP1A3	2.34e-05	11	121	3	CID000010497
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A1 ATP1A2 ATP1A3 ATP1A4	8.43e-09	7	118	4	DOID:0060178 (implicated_via_orthology)
Disease	nervous system disease (implicated_via_orthology)	ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.17e-07	12	118	4	DOID:863 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	KDM5C RHBDL1 RYR2 KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	1.24e-06	195	118	8	DOID:1574 (implicated_via_orthology)
Disease	retinal degeneration (implicated_via_orthology)	IFT172 CEP290 RAB6B RAB6A	9.09e-06	33	118	4	DOID:8466 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease type 2A2A (implicated_via_orthology)	MFN1 MFN2	1.59e-05	2	118	2	DOID:0110155 (implicated_via_orthology)
Disease	ALTERNATING HEMIPLEGIA OF CHILDHOOD 1	ATP1A2 ATP1A3	1.59e-05	2	118	2	C3549447
Disease	Charcot-Marie-Tooth disease type 2A2B (implicated_via_orthology)	MFN1 MFN2	1.59e-05	2	118	2	DOID:0111557 (implicated_via_orthology)
Disease	alternating hemiplegia of childhood (is_implicated_in)	ATP1A2 ATP1A3	1.59e-05	2	118	2	DOID:0050635 (is_implicated_in)
Disease	Bipolar Disorder	HDAC5 NDUFV1 SLC5A3 STK4 GSTZ1 SEC24C EHHADH ATP1A1 ATP1A2 ATP1A3	2.28e-05	477	118	10	C0005586
Disease	epilepsy (implicated_via_orthology)	TNIK KCNMA1 ATP1A1 ATP1A2 ATP1A3 ATP1A4	5.13e-05	163	118	6	DOID:1826 (implicated_via_orthology)
Disease	Alternating hemiplegia of childhood	ATP1A2 ATP1A3	9.46e-05	4	118	2	C0338488
Disease	Charcot-Marie-Tooth disease type 2 (implicated_via_orthology)	MFN1 MFN2	9.46e-05	4	118	2	DOID:0050539 (implicated_via_orthology)
Disease	response to antipsychotic drug	TNIK NBEA ZNF831 CTNNA2	9.97e-05	60	118	4	GO_0097332
Disease	Lipodystrophy	POLD1 BSCL2	1.57e-04	5	118	2	C0023787
Disease	Sarcomatoid Renal Cell Carcinoma	KDM5C BAP1 SLC5A3 KCNMA1 YIPF3	1.68e-04	128	118	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	KDM5C BAP1 SLC5A3 KCNMA1 YIPF3	1.68e-04	128	118	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	KDM5C BAP1 SLC5A3 KCNMA1 YIPF3	1.68e-04	128	118	5	C1266044
Disease	Papillary Renal Cell Carcinoma	KDM5C BAP1 SLC5A3 KCNMA1 YIPF3	1.68e-04	128	118	5	C1306837
Disease	Renal Cell Carcinoma	KDM5C BAP1 SLC5A3 KCNMA1 YIPF3	1.68e-04	128	118	5	C0007134
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	2.35e-04	6	118	2	EFO_0004307, EFO_0008463
Disease	Lissencephaly	MACF1 CTNNA2	2.35e-04	6	118	2	C0266463
Disease	Vestibular Diseases	GSTZ1 ATP1A1	3.29e-04	7	118	2	C0042594
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	KDM5C BAP1 SLC5A3 KCNMA1 YIPF3	3.29e-04	148	118	5	C0279702
Disease	glucagon measurement	TNIK ATP1A1 ATP1A3 ATP1A4 NLRP8	3.95e-04	154	118	5	EFO_0008463
Disease	primary pulmonary hypertension (is_marker_for)	MFN1 MFN2	4.37e-04	8	118	2	DOID:14557 (is_marker_for)
Disease	cups of coffee per day measurement	ATP1A1 ATP1A3 ATP1A4	5.53e-04	40	118	3	EFO_0006782
Disease	cystic kidney disease (implicated_via_orthology)	IFT172 CEP290	6.99e-04	10	118	2	DOID:2975 (implicated_via_orthology)
Disease	calcium measurement	SLC43A2 GPR39 THBS3 NYNRIN SLC22A3 MACF1 ATP1A1 ATP1A3 ATP1A4	9.68e-04	628	118	9	EFO_0004838
Disease	hyperhomocysteinemia (biomarker_via_orthology)	ATP1A1 ATP1A2	1.02e-03	12	118	2	DOID:9279 (biomarker_via_orthology)
Disease	Drug habituation	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0013170
Disease	Drug abuse	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0013146
Disease	Prescription Drug Abuse	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C4316881
Disease	Substance-Related Disorders	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0236969
Disease	Drug Use Disorders	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0013222
Disease	Drug Dependence	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C1510472
Disease	Substance Dependence	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0038580
Disease	Substance Use Disorders	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	MYO6 DDX1 EHHADH SLC22A3	1.19e-03	115	118	4	C0029231
Disease	Influenza	DDX60 IFI27 IFI35	1.19e-03	52	118	3	C0021400
Disease	velocity of sound measurement	CCDC170 TMEM135	1.20e-03	13	118	2	EFO_0005654
Disease	Bardet-Biedl Syndrome	IFT172 CEP290	1.20e-03	13	118	2	C0752166
Disease	Substance abuse problem	MYO6 DDX1 EHHADH SLC22A3	1.23e-03	116	118	4	C0740858
Disease	abdominal adipose tissue measurement	ATP1A1 ATP1A3 ATP1A4	1.26e-03	53	118	3	EFO_0803316
Disease	Saldino-Noonan Syndrome	IFT172 C2CD3	1.40e-03	14	118	2	C0036069
Disease	polycystic kidney disease (implicated_via_orthology)	IFT172 PKD1	1.40e-03	14	118	2	DOID:0080322 (implicated_via_orthology)
Disease	Osteopenia	SLC5A6 KCNMA1	1.61e-03	15	118	2	C0029453
Disease	Endometrial Neoplasms	PLXNA3 POLD1 CHD4	1.64e-03	58	118	3	C0014170
Disease	Global developmental delay	KDM5C NBEA SLC5A6 CTNNA2	2.04e-03	133	118	4	C0557874
Disease	Multiple congenital anomalies	POLD1 HAAO	2.07e-03	17	118	2	C0000772
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	IFI35 PMPCA EEPD1 SLC22A3 MACF1	2.15e-03	225	118	5	EFO_0008317, EFO_0020947
Disease	Intellectual Disability	KDM5C TMEM135 NBEA SLC5A6 MACF1 CTNNA2 ATP1A1	2.18e-03	447	118	7	C3714756
Disease	bipolar I disorder	LRRC3C HDAC5 ANKHD1 STK4	2.52e-03	141	118	4	EFO_0009963
Disease	anorectal malformation	NLRP8 KLHL17	2.59e-03	19	118	2	MONDO_0019938
Disease	Manic Disorder	HDAC5 SLC5A3 STK4	2.92e-03	71	118	3	C0024713
Disease	Endometrial Carcinoma	PLXNA3 POLD1 CHD4	3.04e-03	72	118	3	C0476089
Disease	sex interaction measurement, cerebral amyloid angiopathy	GALNT15 EFHB	3.17e-03	21	118	2	EFO_0006790, EFO_0008343
Disease	Paroxysmal atrial fibrillation	SLC35F1 GJA5 GTF2I HERC1	3.62e-03	156	118	4	C0235480
Disease	familial atrial fibrillation	SLC35F1 GJA5 GTF2I HERC1	3.62e-03	156	118	4	C3468561
Disease	Persistent atrial fibrillation	SLC35F1 GJA5 GTF2I HERC1	3.62e-03	156	118	4	C2585653
Disease	Corneal astigmatism	TMEM135 HERC2 VAV2	3.68e-03	77	118	3	EFO_1002040
Disease	Manic	HDAC5 SLC5A3 STK4	3.81e-03	78	118	3	C0338831
Disease	atrial fibrillation	POLD1 SLC35F1 GJA5 GTF2I HERC1 MXD1	3.84e-03	371	118	6	EFO_0000275
Disease	smoking status measurement, diastolic blood pressure	TPRA1 ZNF831 PLEKHG1 LSM8	3.87e-03	159	118	4	EFO_0006336, EFO_0006527
Disease	Depression, Bipolar	HDAC5 SLC5A3 STK4	3.95e-03	79	118	3	C0005587
Disease	Atrial Fibrillation	SLC35F1 GJA5 GTF2I HERC1	3.96e-03	160	118	4	C0004238

Protein segments in the cluster

Peptide	Gene	Start	Entry
MVQIVISSARAGGLA	CHTF8	1	P0CG13
SSVVTMGGRRLSLAP	HAAO	236	P46952
RMRAAVLSGLGLSTL	ADCY6	256	O43306
GRVRLMVTGAAPVSA	ACSL1	426	P33121
SARATVSIMIGVLAR	CEACAM8	331	P31997
VVLDTTMRGGRLGVF	COMP	711	P49747
TVIARRAGMAASLTV	FAT4	4061	Q6V0I7
ARRVIMERIGLATAG	BAP1	206	Q92560
MTLPGVTRAVARSIV	EEPD1	51	Q7L9B9
RGTDGAVSEMVLRSV	PCDHA9	571	Q9Y5H5
AVSEMVLRSVGAGVV	PCDHA9	576	Q9Y5H5
RRTSTFALTIIVGVM	UQCR10	16	Q9UDW1
VRTERGSDVIIMLVG	RAB6A	111	P20340
VRTERGSDVIIMLVG	RAB6B	111	Q9NRW1
LVIVMTTRFEEGGRR	PTPN9	396	P43378
GARRSTDVALLVTMG	LRRC3C	216	A6NJW4
VTSRTSMGIIIVGGV	MFN1	591	Q8IWA4
VMGTLRSLGALARAA	MFSD10	396	Q14728
ARIATVVIGGVVAMA	IFI27	31	P40305
RGLSVIDMGLSTVTL	OR1B1	66	Q8NGR6
FVMGLLGNSATIRVT	GPR39	41	O43194
EVRMTLGLVASVLVG	GPR61	151	Q9BZJ8
VRSDVAMTGEITLRG	LONP2	761	Q86WA8
LGIERIRMDSIGSTV	MXD1	136	Q05195
AGVMISAQTLTGRVL	KCNMA1	166	Q12791
QTGVTAFLGMSILRR	NLRP8	481	Q86W28
TVMDGVNRIVSVRSG	HERC2	3656	O95714
LVRILRSTVMVRVGG	DST	7321	Q03001
GLIRTRMLGASVATG	GALNT10	216	Q86SR1
VTTVGRRLSVGSSMR	SLC43A2	266	Q8N370
TGDRTVMGRIATLAS	ATP1A1	261	P05023
DTGRMGSRLVGIISS	IMPDH2	146	P12268
RSSTDALIEMGVRTG	HERC1	151	Q15751
GARLGRMISSISETE	MAPK8IP2	261	Q13387
RVVTATGTLALGVNM	DDX60	1286	Q8IY21
LGAIRARMLGATRAT	GALNT15	261	Q8N3T1
ARMLGATRATGDVLV	GALNT15	266	Q8N3T1
VLTLITDGMRSVRAF	CPSF1	346	Q10570
VGRAERMGLAISLVA	DDX1	606	Q92499
GTMGRGIVISFARAR	EHHADH	306	Q08426
RGTVASLTMVALQSR	PLXNA3	1361	P51805
MSSQLSGRRVLVTGF	IFI35	126	P80217
LVRILRSTVMVRVGG	MACF1	3286	O94854
AMVRLAVGSRVVTVS	GPKOW	271	Q92917
IVRLEGVVTRGSTLM	EPHA10	706	Q5JZY3
MAVVGVSSVSRLLGR	COX6A1	1	P12074
RMTIIGVILSFRSLA	NCKAP1	906	Q9Y2A7
GLASLTSRTSMGILV	MFN2	606	O95140
TSRTSMGILVVGGVV	MFN2	611	O95140
ERVTMFTIRGDVIGL	IFT172	556	Q9UG01
LAVVVLSLALGMSGR	MOGS	46	Q13724
QGSILSRARLTVVMS	PRTG	401	Q2VWP7
TARGIVIATGDRTVM	ATP1A2	251	P50993
VIATGDRTVMGRIAT	ATP1A2	256	P50993
DRTVMGRIATLASGL	ATP1A2	261	P50993
VVASMSTRRARVGVA	KLHL17	371	Q6TDP4
MLSRRSSAGVAVLEG	KLHL17	516	Q6TDP4
TRVASMSTRRLGVAV	KLHL20	441	Q9Y2M5
MSTRRLGVAVAVLGG	KLHL20	446	Q9Y2M5
PVVAMTSRRSGVGLA	KLHL20	536	Q9Y2M5
GRTHSVRIIIETMGV	C2CD3	536	Q4AC94
GISFVTSVTRLMERL	DOCK3	1186	Q8IZD9
GTMVRAARALLSAVT	CTNNA2	121	P26232
TTGMTVDQVLGIRAL	CEP290	1966	O15078
SILIRTTMEVGFIVG	GJA5	156	P36382
GMTFNLIGESTIRRT	CR1L	511	Q2VPA4
MSVSVLSPSRRLGGV	CYP4A22	1	Q5TCH4
LVRSQRATGIGRLMV	ITSN1	1586	Q15811
GTAMRILGGVISAIS	CAPNS1	56	P04632
RASVRMISDLIAGGI	GSTZ1	96	O43708
RTVAVITSDGRMIVG	LSM8	11	O95777
GVVVATGDRTVMGRI	ATP1A3	246	P13637
TGDRTVMGRIATLAS	ATP1A3	251	P13637
RTVMQRGSLGVDSVS	EFHB	81	Q8N7U6
ISTRGTSAGMVREGQ	FAM118B	321	Q9BPY3
AALLRGRLSMTGSTE	CCDC170	331	Q8IYT3
LGGVTRLTESGLSMV	COX15	86	Q7KZN9
LVTGERVATSMRTVG	HDAC5	471	Q9UQL6
SAMRRLGVVGEFSLI	GRM1	301	Q13255
GGRVMVTDADRSILS	GTF2I	196	P78347
GGRIISTSSRSVMLH	BSCL2	136	Q96G97
GLSRQHVLTRIGVMS	CHD4	1486	Q14839
VVGFDAVMRVRTSTG	SEC24C	746	P53992
AVMRVRTSTGIRAVD	SEC24C	751	P53992
TTVATLGRLGITMAF	SLC22A3	436	O75751
ASLGQIRSLLSVRMG	RYR2	2121	Q92736
TGRRDTKVVSMVGRV	POLD1	441	P28340
TTSTGSAGMRLVLRR	PKD1	2421	P98161
GLRRVVIDGSSVAMV	NYNRIN	791	Q9P2P1
RILGAILAMASTQSR	OR10P1	221	Q8NGE3
SLSSMTRVVGGLVAL	F12	366	P00748
MAAVVLAATRLLRGS	PMPCA	1	Q10713
MAALGTVLFTGVRRL	MRPL52	1	Q86TS9
RIARRATATMIAGSL	TNFRSF21	16	O75509
SGSIIAVAMQRGARL	POMT2	611	Q9UKY4
RGRVVNVSSVMGRVS	RDH16	156	O75452
RESVGLVSMFRGLGI	PIWIL2	66	Q8TC59
SRGMRSVVGFVASIN	PIWIL2	751	Q8TC59
VGLIVSLLTGRMRGR	SLC5A6	541	Q9Y289
QTGLGTAAVIVMDRS	NDUFV1	346	P49821
QRTLITGMASGSIVA	NBEA	2916	Q8NFP9
ARVMATIGVTRGLGD	PPM1J	371	Q5JR12
SSVALRSILRQIMTG	RNF6	476	Q9Y252
SASSRELMIVGRIFV	SLC5A3	401	P53794
GVLAGSLTVSITDMR	RHBDL1	291	O75783
RMITIRGGTESTRYA	ANKHD1	1741	Q8IWZ3
TARGIVIATGDSTVM	ATP1A4	261	Q13733
IRTLSRVEFLGMIGL	SLC35F1	241	Q5T1Q4
ALVGIARAVVSMTVS	TPRA1	91	Q86W33
SISREGTLMIRETSG	TNIK	896	Q9UKE5
MAAVGSLLGRLRQST	MRPL55	1	Q7Z7F7
TAIGMVLLGTRGATA	SERPINB13	36	Q9UIV8
TLFRMGVARGTITTL	TMEM135	136	Q86UB9
RMVVLGASRVGKSSI	RASD2	21	Q96D21
QTFIRLEGSMRTLVG	TMCO6	101	Q96DC7
MLRTSVLRLLGRTGA	MARS2	1	Q96GW9
VIIDTSMRGGRLGVF	THBS3	906	P49746
ARTGGMVVITVLLSV	UPK2	151	O00526
TIIREGTLMGTAIGT	YIPF3	176	Q9GZM5
STLRMVAVLVSRTVG	YIPF3	256	Q9GZM5
VRAVGDEMGTVRVAS	STK4	331	Q13043
SSTMISVLRAGGALR	PLEKHG1	516	Q9ULL1
IGDAIRMIVRGTLGS	PLK2	441	Q9NYY3
STMGSVADTVARVLR	PLK2	466	Q9NYY3
RAIDVSVMVGGSTLA	VAV2	256	P52735
TMTRLSESRVLVLGG	LCMT2	421	O60294
GTLSLGTSSRIVREM	ZNF831	1376	Q5JPB2
IGLLSTLRGRARAMS	TTLL10	226	Q6ZVT0
LGTSVARTGLVMQET	XIRP1	886	Q702N8
LLMVTTIVLGRRFIG	TMEM39B	126	Q9GZU3
VLLSMLREGTSVSVG	UCMA	16	Q8WVF2
SARRGTLAVMRGLLV	KDM5C	941	P41229
TLAVMRGLLVAGASV	KDM5C	946	P41229
LRVSLTTRVMLTTAG	MYO6	386	Q9UM54
RAMLAGSARRKVTGT	MYOZ3	71	Q8TDC0