Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	HCN4 SCN1A HCN2	1.45e-04	26	79	3	GO:0005248
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	TBC1D10A ARHGEF7 ARFGEF2 PLCG1 ARHGEF37 ARHGEF17	3.09e-04	231	79	6	GO:0005085
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	PCLO BSN	4.26e-04	8	79	2	GO:0098882
GeneOntologyMolecularFunction	retromer complex binding	WASHC2C WASHC2A	6.81e-04	10	79	2	GO:1905394
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	HCN4 HCN2	6.81e-04	10	79	2	GO:0005222
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	WASHC2C ARHGAP9 WASHC2A	9.63e-04	49	79	3	GO:0005547
GeneOntologyMolecularFunction	sodium channel activity	HCN4 SCN1A HCN2	1.15e-03	52	79	3	GO:0005272
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	HCN4 HCN2	1.17e-03	13	79	2	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	HCN4 HCN2	1.17e-03	13	79	2	GO:0043855
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	BLM ERCC6 NAV2 SRCAP	1.62e-03	127	79	4	GO:0008094
GeneOntologyMolecularFunction	transcription corepressor binding	PCLO PER1 BSN	1.65e-03	59	79	3	GO:0001222
GeneOntologyMolecularFunction	3'-5' DNA helicase activity	BLM NAV2	1.79e-03	16	79	2	GO:0043138
GeneOntologyMolecularFunction	DNA helicase activity	BLM ERCC6 NAV2	1.91e-03	62	79	3	GO:0003678
GeneOntologyMolecularFunction	transcription coregulator binding	PCLO PER1 VGLL4 BSN	2.32e-03	140	79	4	GO:0001221
GeneOntologyMolecularFunction	helicase activity	BLM ERCC6 NAV2 SRCAP	3.58e-03	158	79	4	GO:0004386
GeneOntologyMolecularFunction	phosphatidylinositol-5-phosphate binding	WASHC2C WASHC2A	3.70e-03	23	79	2	GO:0010314
GeneOntologyMolecularFunction	cytoskeletal protein binding	SPIRE2 HAP1 ARHGEF7 ARFGEF2 MAST1 COBL AFDN LIMCH1 CORO1B WIPF2 KIFC1	3.88e-03	1099	79	11	GO:0008092
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D10A ARHGEF7 ARFGEF2 ARHGAP9 PLCG1 ARHGEF37 ARHGEF17	3.92e-03	507	79	7	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D10A ARHGEF7 ARFGEF2 ARHGAP9 PLCG1 ARHGEF37 ARHGEF17	3.92e-03	507	79	7	GO:0030695
GeneOntologyBiologicalProcess	presynaptic active zone assembly	PCLO BSN PCDH17	4.98e-07	5	77	3	GO:1904071
GeneOntologyBiologicalProcess	positive regulation of lamellipodium morphogenesis	ARHGEF7 CORO1B RREB1	1.73e-06	7	77	3	GO:2000394
GeneOntologyBiologicalProcess	presynaptic active zone organization	PCLO BSN PCDH17	5.89e-06	10	77	3	GO:1990709
GeneOntologyBiologicalProcess	regulation of lamellipodium morphogenesis	ARHGEF7 CORO1B RREB1	8.08e-06	11	77	3	GO:2000392
GeneOntologyBiologicalProcess	cell junction assembly	CACNA1A ARHGEF7 PCLO PCDHB5 PCDHB8 PCDHB4 AFDN LIMCH1 BSN PCDH17 CLDN9	8.22e-06	569	77	11	GO:0034329
GeneOntologyBiologicalProcess	synapse assembly	CACNA1A PCLO PCDHB5 PCDHB8 PCDHB4 AFDN BSN PCDH17	1.94e-05	308	77	8	GO:0007416
GeneOntologyBiologicalProcess	lamellipodium morphogenesis	ARHGEF7 CORO1B RREB1	3.92e-05	18	77	3	GO:0072673
GeneOntologyBiologicalProcess	presynapse to nucleus signaling pathway	PCLO BSN	4.12e-05	3	77	2	GO:0099526
GeneOntologyBiologicalProcess	synaptic vesicle clustering	PCLO BSN PCDH17	7.32e-05	22	77	3	GO:0097091
GeneOntologyBiologicalProcess	presynaptic signal transduction	PCLO BSN	8.21e-05	4	77	2	GO:0098928
GeneOntologyBiologicalProcess	actin nucleation	SPIRE2 WASHC2C CORO1B WASHC2A	1.02e-04	65	77	4	GO:0045010
GeneOntologyBiologicalProcess	actin filament-based process	SPIRE2 WASHC2C HCN4 ARHGEF7 SCN1A PCLO COBL LIMCH1 CORO1B ARHGEF17 WASHC2A ZBED3	1.35e-04	912	77	12	GO:0030029
GeneOntologyBiologicalProcess	presynaptic actin cytoskeleton organization	ARHGEF7 PCLO	1.37e-04	5	77	2	GO:0099140
GeneOntologyBiologicalProcess	presynapse organization	ARHGEF7 PCLO BSN PCDH17	1.61e-04	73	77	4	GO:0099172
GeneOntologyBiologicalProcess	vesicle-mediated transport in synapse	CACNA1A AP2A1 OTOF HAP1 PCLO BSN PCDH17	1.96e-04	321	77	7	GO:0099003
GeneOntologyBiologicalProcess	presynaptic cytoskeleton organization	ARHGEF7 PCLO	2.04e-04	6	77	2	GO:0099187
GeneOntologyBiologicalProcess	maintenance of presynaptic active zone structure	PCLO BSN	2.04e-04	6	77	2	GO:0048790
GeneOntologyBiologicalProcess	regulation of Arp2/3 complex-mediated actin nucleation	WASHC2C CORO1B WASHC2A	2.09e-04	31	77	3	GO:0034315
GeneOntologyBiologicalProcess	synapse organization	CACNA1A DIP2A ARHGEF7 PCLO PCDHB5 PCDHB8 PCDHB4 AFDN BSN PCDH17	2.25e-04	685	77	10	GO:0050808
GeneOntologyBiologicalProcess	cell junction organization	CACNA1A DIP2A ARHGEF7 PCLO PCDHB5 PCDHB8 PCDHB4 AFDN LIMCH1 BSN PCDH17 CLDN9	2.48e-04	974	77	12	GO:0034330
GeneOntologyBiologicalProcess	cellular response to cGMP	HCN4 HCN2	2.85e-04	7	77	2	GO:0071321
GeneOntologyBiologicalProcess	membrane depolarization during action potential	HCN4 SCN1A HCN2	3.27e-04	36	77	3	GO:0086010
GeneOntologyBiologicalProcess	positive regulation of lamellipodium organization	ARHGEF7 CORO1B RREB1	4.47e-04	40	77	3	GO:1902745
GeneOntologyBiologicalProcess	synaptic vesicle cycle	CACNA1A AP2A1 OTOF PCLO BSN PCDH17	4.61e-04	264	77	6	GO:0099504
GeneOntologyBiologicalProcess	regulation of actin nucleation	WASHC2C CORO1B WASHC2A	4.81e-04	41	77	3	GO:0051125
GeneOntologyBiologicalProcess	response to cGMP	HCN4 HCN2	4.87e-04	9	77	2	GO:0070305
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	CACNA1A OTOF HAP1 PCLO PCDHB5 PCDHB8 PCDHB4 AFDN PLCG1 BSN PCDH17	6.53e-04	931	77	11	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	CACNA1A OTOF HAP1 PCLO PCDHB5 PCDHB8 PCDHB4 AFDN PLCG1 BSN PCDH17	6.53e-04	931	77	11	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	CACNA1A OTOF HAP1 PCLO PCDHB5 PCDHB8 PCDHB4 AFDN PLCG1 BSN PCDH17	7.00e-04	939	77	11	GO:0099537
GeneOntologyBiologicalProcess	Arp2/3 complex-mediated actin nucleation	WASHC2C CORO1B WASHC2A	7.21e-04	47	77	3	GO:0034314
GeneOntologyBiologicalProcess	actin filament network formation	SPIRE2 COBL	7.40e-04	11	77	2	GO:0051639
GeneOntologyBiologicalProcess	actin cytoskeleton organization	SPIRE2 WASHC2C ARHGEF7 PCLO COBL LIMCH1 CORO1B ARHGEF17 WASHC2A ZBED3	7.84e-04	803	77	10	GO:0030036
GeneOntologyCellularComponent	GABA-ergic synapse	HAP1 ARHGEF7 PCLO ARFGEF2 BSN PCDH17	3.68e-05	164	79	6	GO:0098982
GeneOntologyCellularComponent	HCN channel complex	HCN4 HCN2	8.42e-05	4	79	2	GO:0098855
GeneOntologyCellularComponent	somatodendritic compartment	CACNA1A DIP2A HCN4 HAP1 ARHGEF7 SCN1A PCLO ARFGEF2 MAST1 COBL AFDN BSN HCN2 GPR179	1.86e-04	1228	79	14	GO:0036477
GeneOntologyCellularComponent	presynaptic active zone	CACNA1A OTOF PCLO AFDN BSN	1.96e-04	141	79	5	GO:0048786
GeneOntologyCellularComponent	cochlear hair cell ribbon synapse	OTOF BSN	2.09e-04	6	79	2	GO:0098683
GeneOntologyCellularComponent	ribbon synapse	OTOF PCLO BSN	2.38e-04	32	79	3	GO:0097470
GeneOntologyCellularComponent	dendrite	CACNA1A DIP2A HCN4 HAP1 PCLO ARFGEF2 MAST1 COBL BSN HCN2 GPR179	3.69e-04	858	79	11	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1A DIP2A HCN4 HAP1 PCLO ARFGEF2 MAST1 COBL BSN HCN2 GPR179	3.76e-04	860	79	11	GO:0097447
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	PCLO BSN	3.89e-04	8	79	2	GO:0048788
GeneOntologyCellularComponent	postsynapse	CACNA1A DIP2A AP2A1 HAP1 ARHGEF7 PCLO PCDHB8 ARFGEF2 AFDN BSN PCDH17 GPR179	4.19e-04	1018	79	12	GO:0098794
GeneOntologyCellularComponent	presynapse	S1PR5 CACNA1A OTOF HCN4 HAP1 SCN1A PCLO ARFGEF2 AFDN BSN PCDH17	4.83e-04	886	79	11	GO:0098793
GeneOntologyCellularComponent	presynaptic cytoskeleton	PCLO BSN	1.25e-03	14	79	2	GO:0099569
GeneOntologyCellularComponent	WASH complex	WASHC2C WASHC2A	1.43e-03	15	79	2	GO:0071203
GeneOntologyCellularComponent	synaptic membrane	CACNA1A OTOF SCN1A PCDHB8 AFDN BSN PCDH17 GPR179	1.60e-03	583	79	8	GO:0097060
GeneOntologyCellularComponent	axon	HCN4 HAP1 ARHGEF7 SCN1A PCLO MAST1 COBL AFDN BSN HCN2	1.89e-03	891	79	10	GO:0030424
GeneOntologyCellularComponent	dendrite terminus	COBL GPR179	2.56e-03	20	79	2	GO:0044292
Domain	CCDC74_C	CCDC74B CCDC74A	1.72e-05	2	78	2	PF14917
Domain	CCDC74	CCDC74B CCDC74A	1.72e-05	2	78	2	IPR033226
Domain	Znf_piccolo	PCLO BSN	1.72e-05	2	78	2	IPR008899
Domain	CCDC74_C	CCDC74B CCDC74A	1.72e-05	2	78	2	IPR029422
Domain	zf-piccolo	PCLO BSN	1.72e-05	2	78	2	PF05715
Domain	FAM21	WASHC2C WASHC2A	1.72e-05	2	78	2	IPR027308
Domain	FAM21/CAPZIP	WASHC2C WASHC2A	5.15e-05	3	78	2	IPR029341
Domain	CAP-ZIP_m	WASHC2C WASHC2A	5.15e-05	3	78	2	PF15255
Domain	WH2_dom	SPIRE2 COBL WIPF2	8.83e-05	21	78	3	IPR003124
Domain	Ion_trans_N	HCN4 HCN2	1.03e-04	4	78	2	PF08412
Domain	Ion_trans_N	HCN4 HCN2	1.03e-04	4	78	2	IPR013621
Domain	WH2	SPIRE2 COBL WIPF2	1.33e-04	24	78	3	PS51082
Domain	Cadherin_2	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.57e-04	65	78	4	PF08266
Domain	Cadherin_N	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.57e-04	65	78	4	IPR013164
Domain	Cadherin_C	PCDHB5 PCDHB8 PCDHB4	7.15e-04	42	78	3	IPR032455
Domain	Cadherin_C_2	PCDHB5 PCDHB8 PCDHB4	7.15e-04	42	78	3	PF16492
Domain	Cadherin_CS	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.12e-03	109	78	4	IPR020894
Domain	CADHERIN_1	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.28e-03	113	78	4	PS00232
Domain	Cadherin	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.28e-03	113	78	4	PF00028
Domain	Ion_trans_dom	CACNA1A HCN4 SCN1A HCN2	1.33e-03	114	78	4	IPR005821
Domain	Ion_trans	CACNA1A HCN4 SCN1A HCN2	1.33e-03	114	78	4	PF00520
Domain	CADHERIN_2	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.33e-03	114	78	4	PS50268
Domain	-	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.33e-03	114	78	4	2.60.40.60
Domain	CA	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.37e-03	115	78	4	SM00112
Domain	Cadherin-like	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.41e-03	116	78	4	IPR015919
Domain	Cadherin	PCDHB5 PCDHB8 PCDHB4 PCDH17	1.51e-03	118	78	4	IPR002126
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN4 HCN2	1.52e-03	14	78	2	IPR003938
Domain	WH2	COBL WIPF2	1.52e-03	14	78	2	SM00246
Domain	cNMP-bd_CS	HCN4 HCN2	1.99e-03	16	78	2	IPR018488
Domain	WH2	COBL WIPF2	1.99e-03	16	78	2	PF02205
Domain	C2	OTOF PCLO PLCG1 C2CD4C	2.21e-03	131	78	4	PF00168
Domain	DH_1	ARHGEF7 ARHGEF37 ARHGEF17	2.32e-03	63	78	3	PS00741
Domain	CH	ARHGEF7 NAV2 LIMCH1	2.54e-03	65	78	3	SM00033
Domain	C2	OTOF PCLO PLCG1 C2CD4C	2.60e-03	137	78	4	SM00239
Domain	VWC_out	FRAS1 MUC5AC	2.81e-03	19	78	2	SM00215
Domain	RhoGEF	ARHGEF7 ARHGEF37 ARHGEF17	2.89e-03	68	78	3	SM00325
Domain	C2	OTOF PCLO PLCG1 C2CD4C	2.96e-03	142	78	4	PS50004
Domain	RhoGEF	ARHGEF7 ARHGEF37 ARHGEF17	3.14e-03	70	78	3	PF00621
Domain	CH	ARHGEF7 NAV2 LIMCH1	3.14e-03	70	78	3	PF00307
Domain	DH_2	ARHGEF7 ARHGEF37 ARHGEF17	3.14e-03	70	78	3	PS50010
Domain	DH-domain	ARHGEF7 ARHGEF37 ARHGEF17	3.27e-03	71	78	3	IPR000219
Domain	-	ARHGEF7 ARHGEF37 ARHGEF17	3.27e-03	71	78	3	1.20.900.10
Domain	-	ARHGEF7 NAV2 LIMCH1	3.27e-03	71	78	3	1.10.418.10
Domain	-	OTOF PCLO PLCG1 C2CD4C	3.43e-03	148	78	4	2.60.40.150
Domain	CH	ARHGEF7 NAV2 LIMCH1	3.53e-03	73	78	3	PS50021
Domain	CH-domain	ARHGEF7 NAV2 LIMCH1	3.81e-03	75	78	3	IPR001715
Domain	C2_dom	OTOF PCLO PLCG1 C2CD4C	4.94e-03	164	78	4	IPR000008
Domain	SH3_1	ARHGEF7 ARHGAP9 PLCG1 ARHGEF37	4.94e-03	164	78	4	PF00018
Domain	FHA	AFDN CEP170B	6.07e-03	28	78	2	SM00240
Domain	VWC	FRAS1 MUC5AC	6.07e-03	28	78	2	PF00093
Domain	AMP-binding	ACSL1 DIP2A	6.94e-03	30	78	2	PF00501
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DIP2A FRAS1 SPIRE2 AP2A1 SZT2 PER1 NAV2 ARFGEF2 COBL PLCG1 CORO1B HUWE1 SRCAP SPEN WASHC2A ZBED3 CEP170B	3.80e-10	1105	79	17	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A USP10 AP2A1 HCN4 ARHGEF7 TBK1 AFDN LIMCH1 CORO1B HUWE1 BSN HCN2 CEP170B LUZP1	3.32e-08	963	79	14	28671696
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A USP10 MLXIPL DIP2A TTC7B AP2A1 PCLO ARFGEF2 MAST1 AFDN LIMCH1 CORO1B BSN ARHGEF17 CEP170B LUZP1	1.16e-07	1431	79	16	37142655
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 WASHC2C MAST1 COBL LIMCH1 ARHGEF17 SPEN WASHC2A CEP170B	3.77e-07	407	79	9	12693553
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BLM WASHC2C TBK1 HUWE1 BSN SRCAP SPEN WASHC2A CEP170B LUZP1	8.95e-07	588	79	10	38580884
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNA1A WASHC2C HCN4 ARHGEF7 SCN1A PCLO PER1 AFDN CORO1B HUWE1 BSN WASHC2A CEP170B	1.66e-06	1139	79	13	36417873
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	CACNA1A PCLO BSN	2.45e-06	12	79	3	28386022
Pubmed	Protocadherins.	PCDHB5 PCDHB8 PCDHB4	3.17e-06	13	79	3	12231349
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	CACNA1A PCLO BSN	4.03e-06	14	79	3	21228161
Pubmed	Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.	HCN4 HCN2	5.09e-06	2	79	2	16806719
Pubmed	Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4.	HCN4 HCN2	5.09e-06	2	79	2	12813043
Pubmed	The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.	HCN4 HCN2	5.09e-06	2	79	2	30877792
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	PCLO BSN	5.09e-06	2	79	2	23403927
Pubmed	Two pacemaker channels from human heart with profoundly different activation kinetics.	HCN4 HCN2	5.09e-06	2	79	2	10228147
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	PCLO BSN	5.09e-06	2	79	2	26793095
Pubmed	An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release.	PCLO PER1	5.09e-06	2	79	2	11285225
Pubmed	Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels.	HCN4 HCN2	5.09e-06	2	79	2	16777944
Pubmed	Identification of a novel Rev-interacting cellular protein.	WASHC2C WASHC2A	5.09e-06	2	79	2	15847701
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	PCLO BSN	5.09e-06	2	79	2	20332206
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	PCLO BSN	5.09e-06	2	79	2	21935939
Pubmed	Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells.	HCN4 HCN2	5.09e-06	2	79	2	12194012
Pubmed	Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).	WASHC2C WASHC2A	5.09e-06	2	79	2	20827171
Pubmed	FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.	WASHC2C WASHC2A	5.09e-06	2	79	2	36717248
Pubmed	TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation.	ACSL1 TBK1	5.09e-06	2	79	2	33152322
Pubmed	Inherited neuronal ion channelopathies: new windows on complex neurological diseases.	CACNA1A SCN1A	5.09e-06	2	79	2	19005038
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	PCLO BSN	5.09e-06	2	79	2	27321892
Pubmed	House dust mite-induced endoplasmic reticulum stress mediates MUC5AC hypersecretion via TBK1 in airway epithelium.	TBK1 MUC5AC	5.09e-06	2	79	2	36719141
Pubmed	Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.	HCN4 HCN2	5.09e-06	2	79	2	15687126
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	PCLO BSN	5.09e-06	2	79	2	32493491
Pubmed	Control of heart rate by cAMP sensitivity of HCN channels.	HCN4 HCN2	5.09e-06	2	79	2	19570998
Pubmed	Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels.	HCN4 HCN2	5.09e-06	2	79	2	19574228
Pubmed	CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.	CCDC74B CCDC74A	5.09e-06	2	79	2	31521166
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	PCLO BSN	5.09e-06	2	79	2	25652077
Pubmed	HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels.	HCN4 HCN2	5.09e-06	2	79	2	17553794
Pubmed	Proteomic analysis of in vivo phosphorylated synaptic proteins.	AP2A1 ARHGEF7 PCLO BSN	6.63e-06	53	79	4	15572359
Pubmed	Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.	PCDHB5 PCDHB8 PCDHB4	7.50e-06	17	79	3	18279309
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	DIP2A SRCAP SPEN	8.98e-06	18	79	3	25363768
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB5 PCDHB8 PCDHB4	1.25e-05	20	79	3	11322959
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1A AP2A1 ARHGEF7 PCLO BSN HCN2 CEP170B	1.45e-05	347	79	7	17114649
Pubmed	Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.	ARHGEF7 PLCG1	1.53e-05	3	79	2	17562871
Pubmed	KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents.	HCN4 HCN2	1.53e-05	3	79	2	12856183
Pubmed	HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.	HCN4 HCN2	1.53e-05	3	79	2	33181864
Pubmed	Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine.	CACNA1A SCN1A	1.53e-05	3	79	2	18056581
Pubmed	Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.	HCN4 HCN2	1.53e-05	3	79	2	22652004
Pubmed	Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation.	ACSL1 MLXIPL	1.53e-05	3	79	2	36054206
Pubmed	Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.	HCN4 HCN2	1.53e-05	3	79	2	21187420
Pubmed	Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.	HCN4 HCN2	1.53e-05	3	79	2	21945247
Pubmed	A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.	HCN4 HCN2	1.53e-05	3	79	2	16079136
Pubmed	Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN2	1.53e-05	3	79	2	22006928
Pubmed	Higher burden of rare frameshift indels in genes related to synaptic transmission separate familial hemiplegic migraine from common types of migraine.	CACNA1A SCN1A	1.53e-05	3	79	2	31980564
Pubmed	Familial Hemiplegic Migraine	CACNA1A SCN1A	1.53e-05	3	79	2	20301562
Pubmed	LIMCH1 suppress the growth of lung cancer by interacting with HUWE1 to sustain p53 stability.	LIMCH1 HUWE1	1.53e-05	3	79	2	31279706
Pubmed	The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families.	CACNA1A SCN1A	1.53e-05	3	79	2	29486580
Pubmed	FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2.	CACNA1A SCN1A	1.53e-05	3	79	2	19007941
Pubmed	Transcriptional control of pacemaker channel genes HCN2 and HCN4 by Sp1 and implications in re-expression of these genes in hypertrophied myocytes.	HCN4 HCN2	1.53e-05	3	79	2	19471099
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BLM USP10 ERCC6 WASHC2C NAV2 AFDN HUWE1 SPEN	1.92e-05	503	79	8	16964243
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB5 PCDHB8 PCDHB4 PCDH17	2.51e-05	74	79	4	10817752
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KSR1 MLXIPL SPIRE2 NAV2 COBL AFDN LIMCH1 ARHGEF17 CEP170B LUZP1	2.53e-05	861	79	10	36931259
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB5 PCDHB8 PCDHB4 PCDH17	2.94e-05	77	79	4	10835267
Pubmed	Functional expression of the human HCN3 channel.	HCN4 HCN2	3.05e-05	4	79	2	16043489
Pubmed	PDK1-AKT signaling pathway regulates the expression and function of cardiac hyperpolarization-activated cyclic nucleotide-modulated channels.	HCN4 HCN2	3.05e-05	4	79	2	32184125
Pubmed	Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.	HCN4 HCN2	3.05e-05	4	79	2	9405696
Pubmed	Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.	HCN4 HCN2	3.05e-05	4	79	2	12928435
Pubmed	Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases.	HCN4 HCN2	3.05e-05	4	79	2	21615589
Pubmed	The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study.	BLM ERCC6	3.05e-05	4	79	2	23322570
Pubmed	Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.	HCN4 HCN2	3.05e-05	4	79	2	20140458
Pubmed	Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder.	HCN4 HCN2	3.05e-05	4	79	2	22748890
Pubmed	Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.	HCN4 HCN2	3.05e-05	4	79	2	9630217
Pubmed	Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes.	CACNA1A SCN1A	3.05e-05	4	79	2	26747084
Pubmed	A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation.	USP10 HUWE1	3.05e-05	4	79	2	26393420
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB5 PCDHB8 PCDHB4 PCDH17	3.42e-05	80	79	4	10716726
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DIP2A PCLO TBK1 ARHGAP9 AMER3 HUWE1 ARHGEF17 QRICH2 PCDH17	4.45e-05	736	79	9	29676528
Pubmed	Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.	HCN4 HCN2	5.07e-05	5	79	2	15564593
Pubmed	The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo.	ARHGEF7 PCLO	5.07e-05	5	79	2	12473661
Pubmed	Developmental HCN channelopathy results in decreased neural progenitor proliferation and microcephaly in mice.	HCN4 HCN2	5.07e-05	5	79	2	34429357
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BLM USP10 WASHC2C ARFGEF2 AFDN LIMCH1 HUWE1 RREB1 SPEN	6.55e-05	774	79	9	15302935
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	USP10 KSR1 AP2A1 TBK1 AFDN CEP170B LUZP1	7.12e-05	446	79	7	24255178
Pubmed	A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.	PCLO BSN	7.60e-05	6	79	2	19812333
Pubmed	Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.	HCN4 HCN2	7.60e-05	6	79	2	25761792
Pubmed	Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.	PCLO BSN	7.60e-05	6	79	2	14734538
Pubmed	Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation.	HCN4 HCN2	7.60e-05	6	79	2	26005035
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	ARHGEF7 AFDN PLCG1 WIPF2	9.19e-05	103	79	4	21706016
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1A USP10 TTC7B WASHC2C ARHGEF7 LIMCH1 WASHC2A	1.05e-04	475	79	7	31040226
Pubmed	Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.	HCN4 HCN2	1.06e-04	7	79	2	27956497
Pubmed	The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium.	IRX5 HCN4	1.06e-04	7	79	2	19255801
Pubmed	Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.	HCN4 HCN2	1.06e-04	7	79	2	19421833
Pubmed	Genetic variation in the DNA repair genes is predictive of outcome in lung cancer.	BLM ERCC6	1.06e-04	7	79	2	17855454
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	AP2A1 ARHGEF7 TBK1 HUWE1 SRCAP SPEN LUZP1 KIFC1	1.10e-04	645	79	8	25281560
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	SZT2 COBL BSN SPEN LUZP1	1.15e-04	208	79	5	33230847
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP10 FAM53A TBK1 MAST1 COBL LIMCH1 VGLL4 PLCG1 HUWE1 ARHGEF37 CEP170B MGRN1	1.30e-04	1489	79	12	28611215
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	WASHC2C AP2A1 ARFGEF2 AFDN WASHC2A	1.34e-04	215	79	5	35973513
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	WASHC2C TBK1 HLCS COBL AFDN CORO1B WASHC2A CEP170B LUZP1	1.37e-04	853	79	9	28718761
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BLM DIP2A KRBA1 ERCC6 NAV2 COBL LIMCH1	1.39e-04	497	79	7	36774506
Pubmed	A FAM21-containing WASH complex regulates retromer-dependent sorting.	WASHC2C WASHC2A	1.41e-04	8	79	2	19922874
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	PCLO TBK1 BSN CEP170B LUZP1	1.43e-04	218	79	5	33378226
Pubmed	NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.	AP2A1 PLCG1	1.82e-04	9	79	2	16710293
Pubmed	Superresolution imaging of chemical synapses in the brain.	PCLO BSN	1.82e-04	9	79	2	21144999
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	BLM ACSL1 KSR1 AP2A1 TBK1 AFDN CORO1B RREB1 DNAAF1 MUC5AC LUZP1	1.93e-04	1321	79	11	27173435
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP36 USP10 SZT2 ARHGEF7 NAV2 BSN MGRN1	2.04e-04	529	79	7	14621295
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 KSR1 ERCC6 TBK1 PER1 HLCS RREB1 SRCAP CEP170B LUZP1	2.15e-04	1116	79	10	31753913
Interaction	HOOK3 interactions	WASHC2C HAP1 HLCS COBL CORO1B HUWE1 WASHC2A LUZP1	1.26e-06	202	79	8	int:HOOK3
Interaction	TOP3B interactions	USP10 DIP2A FRAS1 ANOS1 SPIRE2 AP2A1 SZT2 PER1 NAV2 ARFGEF2 COBL PLCG1 CORO1B HUWE1 SRCAP SPEN WASHC2A ZBED3 CEP170B	2.87e-06	1470	79	19	int:TOP3B
Cytoband	2q21.1	CCDC74B CCDC74A AMER3	1.41e-04	58	79	3	2q21.1
Cytoband	5q31	PCDHB5 PCDHB8 PCDHB4	1.05e-03	115	79	3	5q31
Cytoband	10q11.23	ERCC6 WASHC2A	1.49e-03	33	79	2	10q11.23
Cytoband	16q24.1	USP10 DNAAF1	1.49e-03	33	79	2	16q24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr16q24	USP10 SPIRE2 DNAAF1	1.71e-03	136	79	3	chr16q24
Cytoband	Ensembl 112 genes in cytogenetic band chr2q21	CCDC74B CCDC74A AMER3	2.30e-03	151	79	3	chr2q21
Cytoband	1p36	SPEN LUZP1	3.01e-03	47	79	2	1p36
Cytoband	Ensembl 112 genes in cytogenetic band chr10q11	ERCC6 WASHC2C WASHC2A	4.25e-03	188	79	3	chr10q11
GeneFamily	WASH complex	WASHC2C WASHC2A	1.12e-04	6	50	2	1331
GeneFamily	Cyclic nucleotide gated channels	HCN4 HCN2	3.33e-04	10	50	2	250
GeneFamily	Clustered protocadherins	PCDHB5 PCDHB8 PCDHB4	7.36e-04	64	50	3	20
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO BSN	7.69e-04	15	50	2	26
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF7 ARHGEF37 ARHGEF17	8.06e-04	66	50	3	722
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PCLO C2CD4C	4.45e-03	36	50	2	823
Coexpression	GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP	USP10 KRBA1 ARHGEF7 ARHGAP9 RREB1 SMOX SPEN	1.14e-06	178	79	7	M8996
Coexpression	GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN	ACSL1 IRX5 SZT2 MAST1 VGLL4 RREB1 MUC5AC	2.39e-06	199	79	7	M8388
Coexpression	GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP	ACSL1 ARHGEF7 PER1 ARFGEF2 SPEN LUZP1	2.55e-05	192	79	6	M8272
Coexpression	GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP	USP36 ARHGEF7 ZKSCAN3 VGLL4 RREB1 SPEN	3.20e-05	200	79	6	M3830
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000	MLXIPL KRBA1 IRX5 TTC7B SZT2 HAP1 PCLO PPM1M ARFGEF2 COBL LIMCH1 LUZP1 CLDN9	5.69e-05	985	78	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	BLM MLXIPL KRBA1 IRX5 ERCC6 TTC7B TBC1D10A HAP1 PCLO ARFGEF2 LIMCH1 GPR179 LUZP1	5.93e-05	989	78	13	Facebase_RNAseq_e10.5_Maxillary Arch_1000
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 MLXIPL FRAS1 HCN4 PCLO BSN	6.75e-07	174	79	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 AJAP1 NAV2 COBL LIMCH1	7.46e-07	177	79	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 MLXIPL FRAS1 HCN4 PCLO BSN	7.71e-07	178	79	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A AJAP1 OTOF SCN1A MAST1 BSN	9.96e-07	186	79	6	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A RAD51AP2 MLXIPL PCLO NAV2 HUWE1	1.31e-06	195	79	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A RAD51AP2 MLXIPL PCLO NAV2 HUWE1	1.31e-06	195	79	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 IRX5 NAV2 COBL LIMCH1	1.43e-06	198	79	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A RAD51AP2 MLXIPL FAM53A AMER3	1.10e-05	164	79	5	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	Control\|World / group, cell type (main and fine annotations)	SCN1A NAV2 COBL LIMCH1 MUC5AC	1.23e-05	168	79	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	3'_v3-blood-Hematopoietic_progenitors-HSC-MPP\|blood / Manually curated celltypes from each tissue	PCLO PCDHB5 LIMCH1 ARHGEF17 PCDH17	1.31e-05	170	79	5	1443d7fccc81088dd42dcbb9361e269872542274
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CCDC74B PCLO BSN C2CD4C	1.31e-05	170	79	5	02f0be0aab8ba2d35a83238609352ef3677511c9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A PCLO MAST1 ARHGEF37 BSN	1.34e-05	171	79	5	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	ANOS1 NAV2 COBL AFDN LIMCH1	1.46e-05	174	79	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL HCN4 AMER3 BSN	1.46e-05	174	79	5	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CCDC74B HCN4 PCLO BSN	1.54e-05	176	79	5	2e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell	3'_v3-blood-Hematopoietic_progenitors\|blood / Manually curated celltypes from each tissue	PCLO PCDHB5 LIMCH1 ARHGEF17 PCDH17	1.59e-05	177	79	5	22c77077951889e63489abfabf90900655655c82
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 NAV2 COBL LIMCH1	1.67e-05	179	79	5	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 NAV2 COBL LIMCH1	1.77e-05	181	79	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACSL1 CACNA1A MLXIPL PCLO AMER3	1.77e-05	181	79	5	af031661af28f99d906d8e013b4949133b44a2e6
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL HAP1 FAM53A PCLO	1.86e-05	183	79	5	d23018193b9c0806e0d1a9ac15e6392eb8e96aaf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANOS1 NAV2 COBL AFDN LIMCH1	1.91e-05	184	79	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A SCN1A PCLO MAST1 BSN	1.91e-05	184	79	5	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANOS1 NAV2 COBL AFDN LIMCH1	1.91e-05	184	79	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANOS1 NAV2 COBL AFDN LIMCH1	1.96e-05	185	79	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL SPIRE2 PCLO AMER3	1.96e-05	185	79	5	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	Control-Epithelial_alveolar\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANOS1 IRX5 NAV2 COBL LIMCH1	1.96e-05	185	79	5	3937e026add96a396122139daf8011cfbc60e75c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.01e-05	186	79	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.01e-05	186	79	5	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	ANOS1 NAV2 COBL AFDN LIMCH1	2.01e-05	186	79	5	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.07e-05	187	79	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ARHGEF7 PER1 AFDN RREB1	2.17e-05	189	79	5	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ACSL1 CACNA1A MLXIPL PCLO BSN	2.23e-05	190	79	5	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	LAM-Epithelial-AT1\|LAM / Condition, Lineage and Cell class	ANOS1 NAV2 COBL LIMCH1 SRCAP	2.29e-05	191	79	5	66875b2ec2c510489407f3e433a90cdf74a15094
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ANOS1 IRX5 PCLO MUC5AC	2.34e-05	192	79	5	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A OTOF SCN1A PCLO BSN	2.40e-05	193	79	5	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A OTOF SCN1A PCLO BSN	2.40e-05	193	79	5	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A OTOF SCN1A PCLO BSN	2.40e-05	193	79	5	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SCN1A NAV2 COBL AFDN LIMCH1	2.46e-05	194	79	5	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BLM CACNA1A PCLO PCDHB5 MAST1	2.65e-05	197	79	5	ff4df77117165b6b25315e29b0722cc136eba607
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.72e-05	198	79	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.72e-05	198	79	5	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Control_saline-Epithelial_alveolar\|Control_saline / Treatment groups by lineage, cell group, cell type	ANOS1 IRX5 NAV2 COBL LIMCH1	2.72e-05	198	79	5	532b7ef4ad46fe35ad2c6bdf89f70a17f1a2e2e2
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.78e-05	199	79	5	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 IRX5 NAV2 COBL	2.78e-05	199	79	5	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.78e-05	199	79	5	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	NAV2 COBL AFDN LIMCH1 CEP170B	2.85e-05	200	79	5	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FRAS1 ANOS1 NAV2 COBL LIMCH1	2.85e-05	200	79	5	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	S1PR5 DIP2A PLCG1 HUWE1 SRCAP	2.85e-05	200	79	5	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MLXIPL PCDHB5 PCDHB8 PCDHB4	3.68e-05	105	79	4	c7528276fee8f6d2cb4639069bc87413b0288025
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MLXIPL PCDHB5 PCDHB8 PCDHB4	3.68e-05	105	79	4	7bcf3345a21a1ade717128be127e9fe12ae40011
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MLXIPL PCDHB5 PCDHB8 PCDHB4	3.68e-05	105	79	4	62e89b92bb8c5187ab0205aebd018b4178710bb0
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B1\|390C / Donor, Lineage, Cell class and subclass (all cells)	S1PR5 DIP2A OTOF HCN2	4.57e-05	111	79	4	9972d31966b059aa3446407b73b714b0b06ec815
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-regulatory_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CACNA1A THPO NAV2 AMER3	6.20e-05	120	79	4	85048159084e15bc9c26021be30f5551858f3701
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HAP1 FAM53A SCN1A MUC5AC	1.32e-04	146	79	4	bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCell	droplet-Bladder-nan-3m-Hematologic-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOF TNFRSF13C ARHGAP9 DNAAF1	1.51e-04	151	79	4	a7b1a60d68f0ed17022fe4c97af64f9f08d39fa3
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_C\|367C / Donor, Lineage, Cell class and subclass (all cells)	S1PR5 SPIRE2 OTOF ARHGAP9	1.71e-04	156	79	4	a1b9e7621b646d354c2ccd850ce6a4fa9ff8a026
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A HCN4 PCLO BSN	1.84e-04	159	79	4	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	Control-Epithelial-Ionocyte\|Control / Disease state, Lineage and Cell class	CCDC74B PCLO ARHGEF37 CLDN9	2.02e-04	163	79	4	bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TTC7B SZT2 HLCS CEP170B	2.02e-04	163	79	4	9f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCell	Ciliated_cells-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CCDC74A DNAAF1 PCDH17	2.02e-04	163	79	4	43194c6127df1ce3d29242f719645de3c11fd7c0
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLCS LIMCH1 ARHGEF37 CEP170B	2.02e-04	163	79	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	3'_v3-Lung-Lymphocytic_B-ABC_aged-B_memory\|Lung / Manually curated celltypes from each tissue	CACNA1A CCDC74A TNFRSF13C QRICH2	2.07e-04	164	79	4	7766900740f67dbbe3c4d90fbfdcc1665cee6515
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL IRX5 HCN4	2.12e-04	165	79	4	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 THPO HAP1 MAST1	2.12e-04	165	79	4	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 THPO HAP1 MAST1	2.12e-04	165	79	4	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BLM NAV2 PCDH17 KIFC1	2.21e-04	167	79	4	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL PCLO AMER3	2.27e-04	168	79	4	f3164a85e5630ee8a745c6dba298e1f94ba4d5b8
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL AMER3 GPR179	2.27e-04	168	79	4	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	HMX3 NAV2 COBL LIMCH1	2.37e-04	170	79	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL PCLO AMER3	2.42e-04	171	79	4	fa5cc720bd0045d0307439be547b41d56def5b43
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SCN1A MUC5AC CEP170B PCDH17	2.48e-04	172	79	4	d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SPIRE2 HCN4 SCN1A MAST1	2.53e-04	173	79	4	7e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A HCN4 AMER3 BSN	2.53e-04	173	79	4	07798461d12d04f3dabff03481c999cb07c5af2f
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACSL1 KRBA1 SZT2 ARHGAP9	2.53e-04	173	79	4	20f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLM S1PR5 HCN2 KIFC1	2.53e-04	173	79	4	31784679190fbd95fc23d7c66008eb21b8c7cc5d
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACSL1 CACNA1A MLXIPL AMER3	2.59e-04	174	79	4	019eae059bd9eb107dee8f0d0f574ca36c2c26e1
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A PCLO AMER3 BSN	2.65e-04	175	79	4	c031da47ca63d1133e13530cbf779df9435e22cb
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCN1A PCDHB4 AFDN VGLL4	2.65e-04	175	79	4	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 TBC1D10A SCN1A PCDH17	2.76e-04	177	79	4	d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1\|TCGA-Liver / Sample_Type by Project: Shred V9	FRAS1 ANOS1 HCN4 CCDC74A	2.82e-04	178	79	4	51c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	ANOS1 NAV2 COBL LIMCH1	2.88e-04	179	79	4	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 ANOS1 NAV2 LIMCH1	2.88e-04	179	79	4	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 AJAP1 ARHGEF17 GPR179	2.88e-04	179	79	4	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	CD8+_Memory_T_cell-FLU-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CORO1B ZBED3 CEP170B TG	2.88e-04	179	79	4	7f18dffa85285599662edbcd3f32ab42672bffb8
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51AP2 AJAP1 ARHGEF17 GPR179	2.88e-04	179	79	4	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CCDC74A DNAAF1 MUC5AC	2.95e-04	180	79	4	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL PCLO AMER3	2.95e-04	180	79	4	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFDN LIMCH1 PCDH17 LUZP1	3.01e-04	181	79	4	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA1A HCN4 PCLO BSN	3.07e-04	182	79	4	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL PCLO AMER3	3.07e-04	182	79	4	0e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 TBC1D10A SCN1A PCDH17	3.07e-04	182	79	4	ecb5624c9074cc6449fad961df54c926c2681d54
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HCN4 SCN1A MAST1 CEP170B	3.07e-04	182	79	4	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANOS1 NAV2 COBL LIMCH1	3.14e-04	183	79	4	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	IPF-Epithelial-ATI\|World / Disease state, Lineage and Cell class	NAV2 COBL LIMCH1 SRCAP	3.14e-04	183	79	4	31fef35ecf30162662f24d335d8f0cceacc07039
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	ANOS1 NAV2 COBL LIMCH1	3.14e-04	183	79	4	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANOS1 IRX5 NAV2 COBL	3.14e-04	183	79	4	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A MLXIPL HAP1 AMER3	3.20e-04	184	79	4	1e6f86f9e379cd9f453f6b7185f681b44eb63e09
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FRAS1 TBK1 HLCS QRICH2	3.27e-04	185	79	4	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ANOS1 IRX5 COBL	3.27e-04	185	79	4	c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARHGAP9 HCN2 ARHGEF17 GPR179	3.27e-04	185	79	4	b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
Disease	reticulocyte measurement	USP10 MLXIPL SPIRE2 TBK1 PER1 ARFGEF2 MAST1 ARHGAP9 AFDN BSN RREB1 SMOX	9.90e-06	1053	73	12	EFO_0010700
Disease	Familial or sporadic hemiplegic migraine	CACNA1A SCN1A	1.81e-05	3	73	2	cv:CN295307
Disease	Familial hemiplegic migraine	CACNA1A SCN1A	1.81e-05	3	73	2	cv:C0338484
Disease	mean corpuscular hemoglobin concentration	MLXIPL KRBA1 WASHC2C TBK1 ARFGEF2 MAST1 CORO1B ARHGEF37 RREB1 SMOX	3.80e-04	1105	73	10	EFO_0004528
Disease	infant head circumference	ARFGEF2 PLCG1	6.21e-04	15	73	2	EFO_0004577
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A BSN	9.00e-04	18	73	2	HP_0002373
Disease	reticulocyte count	USP10 MLXIPL SPIRE2 TBK1 MAST1 ARHGAP9 BSN RREB1 SMOX	1.08e-03	1045	73	9	EFO_0007986
Disease	macula measurement	ARHGEF7 NAV2 COBL LIMCH1	1.26e-03	189	73	4	EFO_0008375
Disease	neuroblastoma, cutaneous melanoma	ACSL1 SPIRE2	2.19e-03	28	73	2	EFO_0000389, EFO_0000621

Protein segments in the cluster

Peptide	Gene	Start	Entry
RDPRSGSKASSIDTG	AMER3	356	Q8N944
EFRSSDGRPDSGGTL	AFDN	236	P55196
DRARDPSGSAGLDAR	CACNA1A	866	O00555
GSGGARRSALLDSDE	ACSL1	66	P33121
ADEPSSRSGSPDREG	ARHGEF37	6	A1IGU5
SRSGSPDREGRASED	ARHGEF37	11	A1IGU5
PRERGSSLSGTDDGA	ARFGEF2	271	Q9Y6D5
GDGLSSFDSRGSRPT	AJAP1	161	Q9UKB5
SALDDGRRDPSSNDI	AP2A1	626	O95782
ADATPSGSLARAGEA	CORO1B	436	Q9BR76
ADDDQPSLDSLGRRS	ARHGEF7	746	Q14155
SERADSPAGPESSRR	CEP170B	706	Q9Y4F5
RLAGGSADTVRSPAD	CCDC74A	151	Q96AQ1
RLAGGSADTVRSPAD	CCDC74B	151	Q96LY2
DDSTPDASPGSRRRL	C2CD4C	266	Q8TF44
SGRAEDADSSSGPLA	ERCC6	1371	Q03468
QSPDSDLRASGRSEA	RAD51AP2	121	Q09MP3
GATDRGSPALSSEAL	PCDHB5	531	Q9Y5E4
DPERASLRDSGHGDS	PCDH17	881	O14917
ALDSASGLGPDRTAS	QRICH2	106	Q9H0J4
PRTDELGRSSSGSAF	IRX5	31	P78411
SRRFDAPRLDDGSAG	ARHGEF17	86	Q96PE2
GPGAAAARRLDESLS	ANOS1	26	P23352
PESESRGASLDGERA	KRBA1	86	A5PL33
RGASLDGERASPEAA	KRBA1	91	A5PL33
SEDRGPRLAAGSSLS	FRAS1	1706	Q86XX4
PDASDRSRGSSEAAG	GPR179	2091	Q6PRD1
RDSSPASGTDRDSPE	HMX3	141	A6NHT5
GGAELALRESSSPES	MGRN1	481	O60291
SLTGSPEDRSRGEHS	BSN	966	Q9UPA5
SLDSEAEALDGGPSR	BSN	1131	Q9UPA5
RRGSASGSEPAGDSD	HLCS	76	P50747
SRSDERRGTLSGAPA	KIFC1	351	Q9BW19
GLDSSSTAPSALGER	PER1	806	O15534
DSPEDRSRGEGSSSL	PCLO	1706	Q9Y6V0
SLDRTAPPDGRASAD	PCLO	2246	Q9Y6V0
LDARRESGSGPSTDT	KSR1	186	Q8IVT5
SRPGRGTDSGDFDTL	MUC5AC	1396	P98088
RRSSDPLGDTASNLG	HUWE1	646	Q7Z6Z7
ESRSSALGAADSEGP	HCN4	66	Q9Y3Q4
GTSSAGDSEATDRPR	MAST1	846	Q9Y2H9
GASDRGSPALSSEAL	PCDHB4	531	Q9Y5E5
LSSSRGPGRSAAEEL	BLM	1301	P54132
LSEARTGARPASEAG	HAP1	61	P54257
ASSASEPRRAPDGTD	COBL	1006	O75128
SDSSSPRAAPGEALR	LUZP1	801	Q86V48
QRDAAPLTSSGDRDS	DNAAF1	666	Q8NEP3
TSSASEDEGSLRRPG	DIP2A	136	Q14689
DLARPNAGRSGRDTS	C4orf54	451	D6RIA3
LDGSFSGSERSSPQR	S1PR5	356	Q9H228
SGSERSSPQRDGLDT	S1PR5	361	Q9H228
AAGGLDPQDSARSRL	HCN2	871	Q9UL51
SDGRGSDSESDLPHR	LIMCH1	226	Q9UPQ0
RLGDGLDPDSVSLAS	OTOF	211	Q9HC10
RVGASDRGSPALSSE	PCDHB8	531	Q9UN66
SRESDLGPAGLDSAS	SZT2	1516	Q5T011
RGSARRPDTGDDAAS	GMCL2	26	Q8NEA9
KRSPSDAGRSSGDES	NAV2	1111	Q8IVL1
EGSSSDEDGSRPLTR	SRCAP	3051	Q6ZRS2
DTDSEDPSLRRSAGG	MLXIPL	26	Q9NP71
REPSAAGRLSDSSSE	SCN1A	471	P35498
SIPSRSGASGLDKRD	CLDN9	201	O95484
KDGASSSPESASRRG	VGLL4	256	Q14135
AHRRELESSGAGSSP	ZBED3	96	Q96IU2
SGSRPSSDLQARLGE	SPEN	1076	Q96T58
SRPRANSGGVDLDSS	RREB1	1161	Q92766
HLGIRGSPRDSDAES	SOGA3	741	Q5TF21
LLSNRGSSGDRPEAS	SPIRE2	501	Q8WWL2
SSSPGAADASRRPDS	PPM1M	41	Q96MI6
SSGDSADDPLSRGLR	SMOX	6	Q9NWM0
SPFSGTSLRERGSDA	PLCG1	1221	P19174
ASDSRSKGEPRDSGT	WASHC2C	636	Q9Y4E1
GSRPESSVDLRGAAL	ARHGAP9	376	Q9BRR9
ASDSRSKGEPRDSGT	WASHC2A	636	Q641Q2
NPSDSGRGSSLLDRT	TTC7B	621	Q86TV6
SSPDLGSEGSRERFR	ZKSCAN3	36	Q9BRR0
PAEAGRDTLSRTAGA	USP10	256	Q14694
SGRPQDDTDSSRASL	WIPF2	131	Q8TF74
RAPAAGESLSGTRES	TBC1D10A	11	Q9BXI6
RRLRGASSAEAPDGD	TNFRSF13C	106	Q96RJ3
SPDDSAGASALLRSG	TG	1011	P01266
ESAGLDRRGSSSSSP	USP36	601	Q9P275
DIDSRLSPGGSLADA	TBK1	521	Q9UHD2
RRTLGAPDISSGTSD	THPO	266	P40225
SDGSRRSSGDPRDGD	FAM53A	361	Q6NSI3