Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	MYH9 ATP7B MYO1C DNAH10 MYO7A ZGRF1 MYO19 WRN NVL MCM4 BTAF1 MSH4 DNAH14 DDX11 CLPB DDX3Y POLQ DDX11L8 ATP5F1B	4.16e-07	614	158	19	GO:0140657
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	ZGRF1 WRN MCM4 BTAF1 MSH4 DDX11 POLQ DDX11L8	7.77e-06	127	158	8	GO:0008094
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ZGRF1 POLH WRN MCM4 BTAF1 MSH4 TEP1 DDX11 POLQ DDX11L8 MPG	7.90e-06	262	158	11	GO:0140097
GeneOntologyMolecularFunction	DNA helicase activity	ZGRF1 WRN MCM4 DDX11 POLQ DDX11L8	9.52e-06	62	158	6	GO:0003678
GeneOntologyMolecularFunction	helicase activity	ZGRF1 WRN MCM4 BTAF1 DDX11 DDX3Y POLQ DDX11L8	3.80e-05	158	158	8	GO:0004386
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP7B DNAH10 MYO19 WRN NVL MCM4 BTAF1 DDX11 CLPB DDX3Y POLQ DDX11L8 ATP5F1B	5.07e-05	441	158	13	GO:0016887
GeneOntologyMolecularFunction	5'-3' DNA helicase activity	ZGRF1 DDX11 DDX11L8	7.66e-05	11	158	3	GO:0043139
GeneOntologyMolecularFunction	protein tyrosine kinase activity	FLT1 AXL TEK BCR TTK PRKCD EPHA1	1.58e-04	145	158	7	GO:0004713
GeneOntologyMolecularFunction	G-quadruplex DNA binding	WRN DDX11 DDX11L8	1.66e-04	14	158	3	GO:0051880
GeneOntologyMolecularFunction	microfilament motor activity	MYH9 MYO1C MYO7A MYO19	2.26e-04	38	158	4	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH9 MYO1C DNAH10 MYO7A MYO19 DNAH14	3.55e-04	118	158	6	GO:0003774
GeneOntologyMolecularFunction	triplex DNA binding	DDX11 DDX11L8	3.69e-04	4	158	2	GO:0045142
GeneOntologyMolecularFunction	steroid 21-monooxygenase activity	CYP2D7 CYP21A2	3.69e-04	4	158	2	GO:0004509
GeneOntologyMolecularFunction	progesterone 21-hydroxylase activity	CYP2D7 CYP21A2	3.69e-04	4	158	2	GO:0106309
GeneOntologyMolecularFunction	actin filament binding	MYH9 MYO1C MYO7A MYO19 MTSS1 CAMSAP3 VPS16 GAS2L1	4.61e-04	227	158	8	GO:0051015
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	ZGRF1 POLH WRN MCM4 BTAF1 MSH4 VARS2 TEP1 DDX11 IARS2 DDX3Y POLQ DDX11L8 MPG	6.23e-04	645	158	14	GO:0140640
GeneOntologyMolecularFunction	actin binding	MYH9 MYO1C TRPM7 MYO7A TPRN MYO19 MTSS1 CAMSAP3 VPS16 GAS2L1 DIAPH1	1.54e-03	479	158	11	GO:0003779
GeneOntologyBiologicalProcess	recombinational repair	REC8 ZGRF1 WRN MCM4 INTS3 DMAP1 RIF1 ZSWIM7 POLQ NSMCE4A	2.72e-06	194	159	10	GO:0000725
GeneOntologyBiologicalProcess	double-strand break repair via homologous recombination	REC8 WRN MCM4 INTS3 DMAP1 RIF1 ZSWIM7 POLQ NSMCE4A	1.57e-05	188	159	9	GO:0000724
GeneOntologyBiologicalProcess	DNA recombination	REC8 ZGRF1 WRN MCM4 MSH4 INTS3 TEP1 DMAP1 RIF1 ZSWIM7 POLQ NSMCE4A	2.95e-05	368	159	12	GO:0006310
GeneOntologyBiologicalProcess	DNA duplex unwinding	ZGRF1 WRN MCM4 DDX11 POLQ DDX11L8	3.10e-05	78	159	6	GO:0032508
GeneOntologyBiologicalProcess	DNA repair	REC8 PTTG1 ZGRF1 POLH WRN MCM4 MSH4 INTS3 DMAP1 DDX11 RIF1 ZSWIM7 POLQ DDX11L8 NSMCE4A MPG	4.26e-05	648	159	16	GO:0006281
GeneOntologyBiologicalProcess	double-strand break repair	REC8 ZGRF1 WRN MCM4 INTS3 DMAP1 DDX11 RIF1 ZSWIM7 POLQ NSMCE4A	4.45e-05	324	159	11	GO:0006302
GeneOntologyBiologicalProcess	DNA damage response	REC8 PTTG1 DCUN1D5 ZGRF1 POLH WRN MCM4 MSH4 INTS3 PPP4R3A DMAP1 DDX11 RIF1 PRKCD ZSWIM7 POLQ DDX11L8 NSMCE4A CDK6 MPG	5.04e-05	959	159	20	GO:0006974
GeneOntologyBiologicalProcess	DNA geometric change	ZGRF1 WRN MCM4 DDX11 POLQ DDX11L8	5.40e-05	86	159	6	GO:0032392
GeneOntologyBiologicalProcess	DNA conformation change	ZGRF1 WRN MCM4 DDX11 POLQ DDX11L8	8.89e-05	94	159	6	GO:0071103
GeneOntologyBiologicalProcess	DNA metabolic process	REC8 PTTG1 JADE3 ZGRF1 POLH WRN CAMSAP3 NVL MCM4 MSH4 INTS3 TEP1 DMAP1 DDX11 RIF1 PRKCD ZSWIM7 POLQ DDX11L8 NSMCE4A MPG	8.89e-05	1081	159	21	GO:0006259
GeneOntologyBiologicalProcess	positive regulation of cell-matrix adhesion	MYH9 TEK MAP4K4 EPHA1 CDK6	1.93e-04	69	159	5	GO:0001954
GeneOntologyBiologicalProcess	ventricular system development	ODAD2 CELSR2 HYDIN CDK6	2.05e-04	38	159	4	GO:0021591
Domain	P-loop_NTPase	MYH9 RAB17 MYO1C DNAH10 MYO7A ZGRF1 MYO19 WRN NVL MCM4 BTAF1 MSH4 TEP1 PAPSS2 DNAH14 DDX11 SULT1A2 MYO15B CLPB ERAL1 DDX3Y POLQ SULT4A1 HYDIN ATP5F1B	4.25e-08	848	157	25	IPR027417
Domain	-	RAB17 DNAH10 MYO7A ZGRF1 MYO19 WRN NVL MCM4 BTAF1 MSH4 TEP1 PAPSS2 DNAH14 DDX11 SULT1A2 CLPB ERAL1 DDX3Y POLQ SULT4A1 HYDIN ATP5F1B	3.00e-07	746	157	22	3.40.50.300
Domain	Myosin_head_motor_dom	MYH9 MYO1C MYO7A MYO19 MYO15B	1.58e-05	38	157	5	IPR001609
Domain	MYOSIN_MOTOR	MYH9 MYO1C MYO7A MYO19 MYO15B	1.58e-05	38	157	5	PS51456
Domain	Myosin_head	MYH9 MYO1C MYO7A MYO19 MYO15B	1.58e-05	38	157	5	PF00063
Domain	MYSc	MYH9 MYO1C MYO7A MYO19 MYO15B	1.58e-05	38	157	5	SM00242
Pathway	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	PODXL2 PAPSS2 SULT1A2 SULT4A1	4.30e-05	23	123	4	MM14597
Pathway	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	PODXL2 PAPSS2 SULT1A2 SULT4A1	5.12e-05	24	123	4	M16289
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYH9 CAD DSCAM POLH PRPF8 KIDINS220 RPF2 DOCK7 DIAPH1 CPSF1	3.96e-08	202	161	10	24639526
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GPD2 MYH9 CAD MYO1C DNAH10 COPB1 NOL6 MCM4 PRPF8 UBE4A RIF1 IARS2 KIDINS220 CLPB ERAL1 RPF2 DOCK7 DIAPH1 GEMIN4 CPSF1 PRKCD MAP4K4 ATP5F1B	1.94e-07	1425	161	23	30948266
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	DCUN1D5 COPB1 CENPC JADE3 NOL6 NVL VPS16 INTS3 DMAP1 RIF1 SULT1A2 RPF2 INTS9 MPG	2.15e-07	533	161	14	30554943
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	REC8 MYH9 CAD ZFAT CENPC TRPM7 VARS2 VPS16 MED13L PAPSS2 TTK PPP4R4 DMAP1 UBE4A SCAP CLPB MTF1 CLVS2 CPSF1 R3HDM1 MAP4K4 CDK6	2.33e-07	1327	161	22	32694731
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYH9 CAD MYO1C COPB1 NOL6 NVL MCM4 PRPF8 USP5 RIF1 IARS2 RPF2 DOCK7 GEMIN4 CPSF1	4.29e-07	653	161	15	22586326
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH9 CAD MYO1C WRN BTAF1 PRPF8 TMTC3 DOCK7 MROH7	4.69e-07	202	161	9	33005030
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	CAD COPB1 ARHGAP26 CAMSAP3 CCDC175 BTAF1 VPS16 MED13L INTS3 RIF1	6.24e-07	272	161	10	31010829
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYH9 CAD MYO1C COPB1 CENPC MYO19 NOL6 MCM4 VPS16 PRPF8 PAPSS2 USP5 RIF1 ERAL1 RPF2 DIAPH1 GEMIN4 CPSF1 PRKCD ATP5F1B MPG	1.29e-06	1353	161	21	29467282
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MYH9 MYO1C COPB1 MYO7A ZGRF1 MCM4 VPS16 PRPF8 PPP4R3A USP5 CLPB LPCAT2 RABGAP1L LRP5 MAP4K4 ATP5F1B	2.25e-06	847	161	16	35235311
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	GPD2 MYO1C COPB1 MCM4 VPS16 PRPF8 GPKOW PPP4R3A DMAP1 UBE4A HAUS4 DIAPH1 CKAP2	2.32e-06	560	161	13	35241646
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CAMSAP3 VPS16 BCR TTK DDX11 WDCP RPF2 CKAP2 MAP4K4	2.83e-06	251	161	9	29778605
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MYH9 HTRA1 SYT12 AXL PODXL2 DMAP1 USP5 POGLUT1 SCAP TMTC3 CELSR2 LPCAT2 CPSF1 LRP5 CKAP2 R3HDM1 NOTCH3 ATP5F1B MPG	3.28e-06	1201	161	19	35696571
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	MYH9 COPB1 BTAF1 PRPF8 INTS3 TTK RIF1 PPP2R1B MYO15B ERAL1 DIAPH1 GEMIN4 CPSF1	3.53e-06	582	161	13	20467437
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KDM5B MYH9 ZGRF1 POLH LIN54 CAMSAP3 BCR WDCP DOCK7 GEMIN4 CSTPP1	4.40e-06	418	161	11	34709266
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MYO1C COPB1 MYO19 MCM4 BCR TTK RIF1 IARS2 KIDINS220 ERAL1 CPSF1 INTS9 NSMCE4A	5.46e-06	606	161	13	36538041
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	GPD2 CAD MYO1C TRPM7 SYNM MYO19 VARS2 TTK UBE4A IARS2 CLPB ERAL1 SURF1 RPF2 GEMIN4 CPSF1 PRKCD CKAP2 R3HDM1 CSTPP1 ATP5F1B	6.16e-06	1496	161	21	32877691
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	MYH9 JADE3 AXL SLC38A4 TEP1 RPF2 LRP5 NOTCH3	7.56e-06	214	161	8	22199357
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	KRT13 ARHGAP26 WRN MED13L PRPF8 KLHL22 YOD1 KIDINS220 ERAL1 DOCK7 PRKCD C3 CKAP2 ATP5F1B	8.67e-06	732	161	14	34732716
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	UNC119B MYH9 CAD MYO1C COPB1 TPRN NOL6 MCM4 PRPF8 DOCK7 GEMIN4 CPSF1 DDX3Y C3 GFPT2 MPG	9.40e-06	949	161	16	36574265
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MYO19 NOL6 CAMSAP3 BTAF1 INTS3 PAPSS2 BCR DENND3 WDCP DOCK7 HSD17B11 MAP4K4 DDX11L8	1.15e-05	650	161	13	38777146
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	MYH9 COPB1 MORN1 SYNM MCM4 BTAF1 PRPF8 RIF1 CLPB RPF2 DOCK7 CPSF1 GFPT2	1.21e-05	653	161	13	33742100
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MYH9 CAD NUP210L NOL6 MCM4 PRPF8 BCR DMAP1 USP5 SCAP RFLNB CLPB ERAL1 CPSF1	1.21e-05	754	161	14	35906200
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	CAD COPB1 MCM4 VPS16 USP5 IARS2 ATP5F1B	1.31e-05	166	161	7	35687106
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	GPD2 MYH9 MYO1C COPB1 AXL MCM4 VARS2 PRPF8 PPP4R3A HAUS4 IARS2 POGLUT1 TMTC3 CELSR2 ASXL3 CPSF1 GFPT2 HSD17B11 MAP4K4 ATP5F1B	1.36e-05	1451	161	20	30550785
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	MYH9 CAD MYO1C COPB1 MCM4 PPP2R1B IARS2 TMTC3 ERAL1 DDX3Y HSD17B11 ATP5F1B	1.40e-05	565	161	12	33567341
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	CAD MYO1C TPRN PRPF8 INTS3 PPP4R3A DMAP1 RIF1 PPP2R1B GEMIN4 INTS9 ATP5F1B	1.61e-05	573	161	12	28330616
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PTTG1 MYO1C JADE3 CAMSAP3 MCM4 BTAF1 INTS3 PPP4R3A STK10 RIF1 CPSF1 PRKCD MAP4K4 MPG	1.61e-05	774	161	14	15302935
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CAD BCR USP5 IARS2 KIDINS220 DOCK7 GEMIN4 CPSF1 MAP4K4	1.67e-05	313	161	9	38270169
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	MYH9 MYO1C DSCAM COPB1 TRPM7 SYNM LIN54 NOL6 WRN PODXL2 RIF1 IARS2 KIDINS220 DOCK7	1.68e-05	777	161	14	35844135
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	KDM5B MYH9 MYO1C NOL6 WRN MCM4 PRPF8 BCR KLHL22 YOD1 USP5 PPP2R1B CLPB RPF2 DOCK7 MAP4K4	1.90e-05	1005	161	16	19615732
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	UNC119B KRT13 CAD CENPC TRPM7 SYNM NVL VARS2 PRPF8 TTK UBE4A IARS2 KIDINS220 TMTC3 CLPB ERAL1 RPF2 CKAP2 MAP4K4 ATP5F1B	1.93e-05	1487	161	20	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RAB17 MORN1 FRMPD2 CAMSAP3 BTAF1 ADGRV1 INTS3 TEP1 BCR DNAH14 PPM1H PPP4R4 STK10 PPP2R1B POGLUT1 KIDINS220 RPF2 LRP5 CKAP2 NOTCH3	1.97e-05	1489	161	20	28611215
Pubmed	Occurrence of PG-Lb, a leucine-rich small chondroitin/dermatan sulphate proteoglycan in mammalian epiphyseal cartilage: molecular cloning and sequence analysis of the mouse cDNA.	EPYC VCAN	2.13e-05	2	161	2	8836137
Pubmed	Preeclampsia and Related Cardiovascular Risk: Common Genetic Background.	FLT1 ACOX2	2.13e-05	2	161	2	29971632
Pubmed	KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo.	NOTCH3 CDK6	2.13e-05	2	161	2	25483078
Pubmed	Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.	HTRA1 NOTCH3	2.13e-05	2	161	2	30859180
Pubmed	Werner syndrome protein interacts functionally with translesion DNA polymerases.	POLH WRN	2.13e-05	2	161	2	17563354
Pubmed	Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis.	PAPSS2 VCAN	2.13e-05	2	161	2	29955124
Pubmed	Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway.	TEK LRP5	2.13e-05	2	161	2	26091161
Pubmed	Extracellular matrix structure and tissue stiffness control postnatal lung development through the lipoprotein receptor-related protein 5/Tie2 signaling system.	TEK LRP5	2.13e-05	2	161	2	23841513
Pubmed	Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.	POLH POLQ	2.13e-05	2	161	2	18485835
Pubmed	sVEGF R1 and Tie-2 levels during chemotherapy of lung cancer patients.	FLT1 TEK	2.13e-05	2	161	2	22836649
Pubmed	DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.	POLH POLQ	2.13e-05	2	161	2	17449470
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	MYH9 CAD DCUN1D5 COPB1 MCM4 ADGRV1 DCUN1D4 PPP4R3A KLHL22 DIAPH1 ATP5F1B	2.13e-05	495	161	11	28581483
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	MYH9 KRT13 MYO1C COPB1 GATM PRPF8 PPP4R3A PPP2R1B VCAN GEMIN4 CDK6	2.25e-05	498	161	11	36634849
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	MYH9 COPB1 SYNM POLH PRPF8 KIDINS220 CSTPP1 CDK6	2.75e-05	256	161	8	33397691
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	DCUN1D5 CENPC JADE3 POLH LIN54 WRN NVL BTAF1 GPKOW DMAP1 RIF1 MPG	2.87e-05	608	161	12	36089195
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM5B DSCAM COPB1 TRPM7 SYNM GATM MED13L PRPF8 DMAP1 UBE4A CLPB HECTD2 GFPT2 CKAP2 R3HDM1 SULT4A1 MAP4K4 ATP5F1B	3.06e-05	1285	161	18	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPD2 MYH9 HTRA1 CAD MYO1C COPB1 MYO7A ARHGAP26 NCKIPSD CAMSAP3 BCR GAS2L1 USP5 KIDINS220 MTERF2 VCAN DOCK7 DDX3Y ATP5F1B	3.77e-05	1431	161	19	37142655
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ATP7B DCUN1D5 NVL BCR GPKOW AFAP1L1 IARS2 SCAP TMTC3 DIAPH1 CKAP2 R3HDM1 MAP4K4	4.00e-05	733	161	13	34672954
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	GPD2 CAD MYO1C COPB1 MYO19 NOL6 BTAF1 PRPF8 UBE4A USP5 PPP2R1B IARS2 RFLNB CLPB ERAL1 RPF2 DOCK7 GEMIN4 ATP5F1B	4.10e-05	1440	161	19	30833792
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	CAD NOL6 NVL MCM4 PPP4R3A DMAP1 PPP2R1B CLPB WDCP GFPT2	4.21e-05	440	161	10	34244565
Pubmed	JunB is essential for mammalian placentation.	FLT1 TEK PRL	4.25e-05	15	161	3	10022836
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CAD COPB1 MCM4 PRPF8 PPP4R3A USP5 RIF1 ERAL1 RPF2 DIAPH1 GEMIN4 ATP5F1B	4.56e-05	638	161	12	33239621
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ARHGAP26 MCM4 PRPF8 BCR PPP4R3A USP5 PPP2R1B KIDINS220 TMTC3 CLPB ERAL1 GEMIN4 PRMT9 C3 ATP5F1B	5.09e-05	974	161	15	28675297
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KDM5B TRPM7 NCKIPSD CAMSAP3 BCR TTK PPM1H PPP4R4 STOX2 RABGAP1L DOCK7 CKAP2 R3HDM1 MAP4K4	5.14e-05	861	161	14	36931259
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	CAD MYO1C NOL6 PRPF8	5.20e-05	44	161	4	26471122
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	CAD NOL6 VARS2 VPS16 PRPF8 BCR IARS2 RPF2 ATP5F1B CDK6	5.47e-05	454	161	10	33226137
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	MYH9 MYO1C MYO15B DIAPH1	5.68e-05	45	161	4	22114352
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	MYH9 KRT13 CAD STK10 UBE4A MAP4K4 PRL ATP5F1B	5.72e-05	284	161	8	29459677
Pubmed	TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation.	MYH9 TRPM7	6.37e-05	3	161	2	18394644
Pubmed	Complete inhibition of goiter in mice requires combined gene therapy modification of angiopoietin, vascular endothelial growth factor, and fibroblast growth factor signaling.	FLT1 TEK	6.37e-05	3	161	2	15817662
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX11 DDX11L8	6.37e-05	3	161	2	17611414
Pubmed	Target cell frequency is a genetically determined risk factor in radiation leukaemogenesis.	MTF1 PRKCD	6.37e-05	3	161	2	17704327
Pubmed	Mammalian ChlR1 has a role in heterochromatin organization.	DDX11 DDX11L8	6.37e-05	3	161	2	21854770
Pubmed	Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation.	PTTG1 UBE4A	6.37e-05	3	161	2	15611659
Pubmed	Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia.	AXL BCR	6.37e-05	3	161	2	27856601
Pubmed	Lactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis.	AXL TEK	6.37e-05	3	161	2	23754286
Pubmed	The association of polypoidal choroidal vasculopathy clinical phenotypes with previously reported genetic markers.	HTRA1 C3	6.37e-05	3	161	2	32328755
Pubmed	Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice.	MYO1C MYO7A	6.37e-05	3	161	2	17050716
Pubmed	Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.	MYO7A ADGRV1	6.37e-05	3	161	2	29142287
Pubmed	PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa.	MYO1C MYO7A	6.37e-05	3	161	2	15976448
Pubmed	Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors.	HTRA1 C3	6.37e-05	3	161	2	21402993
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	MYH9 KRT13 CAD MYO1C LIN54 LPCAT2 VCAN GEMIN4 C3 MAP4K4 ATP5F1B	6.91e-05	564	161	11	21565611
Pubmed	ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis.	FLT1 MYH9 PRL	7.55e-05	18	161	3	33842485
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MYH9 KRT13 CAD MYO1C SYNM NOL6 PRPF8 GPKOW AFAP1L1 IARS2 RPF2 DOCK7 GEMIN4 CPSF1 C3 CKAP2 ATP5F1B	7.91e-05	1257	161	17	36526897
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	CAD MYO1C COPB1 MCM4 BTAF1 PRPF8 DDX11 RIF1 PPP2R1B IARS2 CLPB ERAL1 GEMIN4 CPSF1 DDX3Y HSD17B11 ATP5F1B	7.91e-05	1257	161	17	37317656
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	NOL6 PODXL2 MYCBPAP YOD1 STK10 CKAP2 GOLGA7B ATP5F1B	8.77e-05	302	161	8	30561431
Pubmed	Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.	CENPC WRN MAP4K4	8.93e-05	19	161	3	14578343
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CAD ZGRF1 TPRN LIN54 BCR TTK PPP4R3A DDX11 HAUS4 WDCP DIAPH1	9.98e-05	588	161	11	38580884
Pubmed	PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.	PPP4R4 PPP4R3A PPP2R1B	1.05e-04	20	161	3	18715871
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	STARD8 SYNM VARS2 DENND3 PPP4R4 PPP4R3A UBE4A MYO15B SCAP UNC80	1.08e-04	493	161	10	15368895
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	CAD MYO7A PPP4R3A USP5 RPF2 DIAPH1 GEMIN4 MROH7 POLQ ATP5F1B	1.13e-04	496	161	10	31343991
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYH9 CAD COPB1 VPS16 PRPF8 PAPSS2 ERAL1 DOCK7 C3 MAP4K4 ATP5F1B	1.21e-04	601	161	11	33658012
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	GPD2 MYH9 CAD COPB1 MCM4 TTK KIDINS220 DOCK7 GEMIN4 MAP4K4 CSTPP1 ATP5F1B	1.22e-04	708	161	12	39231216
Pubmed	Effect of the Gas6 c.834+7G>A polymorphism and the interaction of known risk factors on AMD pathogenesis in Hungarian patients.	HTRA1 C3	1.27e-04	4	161	2	23209669
Pubmed	Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition.	REC8 PTTG1	1.27e-04	4	161	2	16720305
Pubmed	Identification of hub genes associated with prognosis, diagnosis, immune infiltration and therapeutic drug in liver cancer by integrated analysis.	PTTG1 TTK	1.27e-04	4	161	2	34187556
Pubmed	Expression of VEGF receptors VEFGR-1 and VEGFR-2, angiopoietin receptors Tie-1 and Tie-2 in chorionic villi tree during early pregnancy.	FLT1 TEK	1.27e-04	4	161	2	20164029
Pubmed	Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.	MYO7A ADGRV1	1.27e-04	4	161	2	18463160
Pubmed	TRPM7, a novel regulator of actomyosin contractility and cell adhesion.	MYH9 TRPM7	1.27e-04	4	161	2	16407977
Pubmed	Determination of a gene and environment risk model for age-related macular degeneration.	HTRA1 C3	1.27e-04	4	161	2	20576771
Pubmed	An association of neovascular age-related macular degeneration with polymorphisms of CFH, ARMS2, HTRA1 and C3 genes in Czech population.	HTRA1 C3	1.27e-04	4	161	2	31970928
Pubmed	Proteomic and genomic biomarkers for age-related macular degeneration.	HTRA1 C3	1.27e-04	4	161	2	20238042
Pubmed	Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT).	HTRA1 C3	1.27e-04	4	161	2	23337555
Pubmed	Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta.	FLT1 PRL	1.27e-04	4	161	2	9285590
Pubmed	Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.	HTRA1 C3	1.27e-04	4	161	2	19202148
Pubmed	Whole-exome sequencing of Finnish patients with vascular cognitive impairment.	HTRA1 NOTCH3	1.27e-04	4	161	2	33268848
Pubmed	LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.	TEK LRP5	1.27e-04	4	161	2	22848540
Pubmed	Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms.	WRN PRKCD	1.27e-04	4	161	2	19966859
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	REC8 PTTG1 RCCD1 ZGRF1 MYO19 POLH LIN54 NCKIPSD MCM4 TTK DDX11 USP5 RIF1 HAUS4 RFLNB CKAP2 R3HDM1 POLQ MAP4K4	5.42e-06	939	161	19	M45768
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_CYCLING_DC_CELL	REC8 PTTG1 CENPC RCCD1 ZGRF1 MYO19 LIN54 NCKIPSD NVL MCM4 VPS16 TTK KLHL22 DDX11 USP5 PPP2R1B CLPB ERAL1 GEMIN4 INTS9 ELF4 CKAP2 POLQ NSMCE4A	6.66e-06	1423	161	24	M45722
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000	KDM5B HTRA1 JADE3 MYO7A SYNM AXL ARHGAP26 CAMSAP3 GATM PAPSS2 PPP4R4 RIF1 IARS2 SCAP LPCAT2 HECTD2 VCAN DOCK7 PRKCD DDX3Y ELF4	2.71e-06	880	159	21	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM MTSS1 TEK TMEM132C VCAN IGSF21 HYDIN UNC80	4.83e-08	199	161	9	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	GPD2 DNAH10 MCM4 TTK PPP2R1B MYO15B NBPF9 CKAP2 POLQ	5.04e-08	200	161	9	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPD2 DNAH10 MCM4 TTK PPP2R1B RFLNB CKAP2 POLQ	3.70e-07	184	161	8	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPD2 DNAH10 MCM4 TTK PPP2R1B RFLNB CKAP2 POLQ	3.70e-07	184	161	8	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	GPD2 DNAH10 MCM4 TTK PPP2R1B RFLNB CKAP2 POLQ	3.70e-07	184	161	8	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GPD2 DNAH10 MCM4 TTK PPP2R1B RFLNB CKAP2 POLQ	3.70e-07	184	161	8	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPD2 DNAH10 MCM4 TTK PPP2R1B RFLNB CKAP2 POLQ	3.70e-07	184	161	8	d31d4116d1d196633784863781fa45673607a421
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFAP47 DNAH10 FRMPD2 CCDC175 ODAD2 MYCBPAP WDR93 HYDIN	4.53e-07	189	161	8	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	GPD2 DNAH10 COPB1 CENPC MCM4 TTK CKAP2 CDK6	5.97e-07	196	161	8	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM MTSS1 TEK TMEM132C VCAN IGSF21 UNC80	6.70e-07	199	161	8	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM MTSS1 TEK TMEM132C VCAN IGSF21 UNC80	6.70e-07	199	161	8	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PTTG1 CENPC ZGRF1 TTK DDX11 CKAP2 POLQ PRL	6.70e-07	199	161	8	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DSCAM ARHGAP26 MED13L LPCAT2 C3 IGSF21 MAP4K4	6.95e-07	200	161	8	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	PTTG1 CENPC ZGRF1 MCM4 TTK DDX11 CKAP2 POLQ	6.95e-07	200	161	8	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 DNAH10 FRMPD2 CCDC175 ODAD2 MYCBPAP WDR93 HYDIN	6.95e-07	200	161	8	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DSCAM ARHGAP26 MED13L LPCAT2 C3 IGSF21 MAP4K4	6.95e-07	200	161	8	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DSCAM ARHGAP26 MED13L LPCAT2 C3 IGSF21 MAP4K4	6.95e-07	200	161	8	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DSCAM ARHGAP26 MED13L LPCAT2 C3 IGSF21 MAP4K4	6.95e-07	200	161	8	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 DNAH10 FRMPD2 CCDC175 ODAD2 MYCBPAP WDR93 HYDIN	6.95e-07	200	161	8	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DSCAM ARHGAP26 MED13L LPCAT2 C3 IGSF21 MAP4K4	6.95e-07	200	161	8	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	HTRA1 DSCAM ARHGAP26 MED13L LPCAT2 C3 IGSF21 MAP4K4	6.95e-07	200	161	8	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular\|TCGA-Stomach / Sample_Type by Project: Shred V9	CAD CYP2D7 RCCD1 ZGRF1 NOL6 PPM1H POLQ	7.21e-07	138	161	7	93497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell	VE-mono3\|VE / Condition, Cell_class and T cell subcluster	HTRA1 DSCAM AXL LPCAT2 C3 IGSF21 NOTCH3	2.02e-06	161	161	7	7df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCell	VE-mono3-\|VE / Condition, Cell_class and T cell subcluster	HTRA1 DSCAM AXL LPCAT2 C3 IGSF21 NOTCH3	2.02e-06	161	161	7	4e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTTG1 ZGRF1 TEK TTK DDX11 CKAP2 POLQ	2.20e-06	163	161	7	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 DNAH10 ODAD2 MYCBPAP ACOX2 WDR93 HYDIN	3.79e-06	177	161	7	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 DNAH10 ODAD2 MYCBPAP ACOX2 WDR93 HYDIN	3.79e-06	177	161	7	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	STARD8 DSCAM AXL TEK LPCAT2 IGSF21 NOTCH3	4.24e-06	180	161	7	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	MCM4 LCT MYCBPAP TTK DDX11 GFPT2 POLQ	4.72e-06	183	161	7	df8568751205313d149939ea2683097e3652a60b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM DNAH10 ADGRV1 ODAD2 ASXL3 HYDIN UNC80	4.90e-06	184	161	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM DNAH10 ADGRV1 ODAD2 ASXL3 HYDIN UNC80	4.90e-06	184	161	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM DNAH10 ADGRV1 ODAD2 ASXL3 HYDIN UNC80	4.90e-06	184	161	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	MYH9 DNAH10 ARHGAP26 MTSS1 PPP4R3A DIAPH1 ATP5F1B	4.90e-06	184	161	7	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	4.90e-06	184	161	7	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	5.07e-06	185	161	7	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM JADE3 AXL TMEM132C VCAN C3 GFPT2	5.07e-06	185	161	7	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AXL CYP21A2 ADGRV1 TEK VCAN C3 GFPT2	5.44e-06	187	161	7	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	5.64e-06	188	161	7	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	5.64e-06	188	161	7	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	5.84e-06	189	161	7	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	5.84e-06	189	161	7	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	CFAP47 DNAH10 FRMPD2 CCDC175 ODAD2 WDR93 HYDIN	5.84e-06	189	161	7	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 ZGRF1 TEK TTK AFAP1L1 CKAP2 POLQ	6.04e-06	190	161	7	31de1727822e9818652946dfb962daee77ffad68
ToppCell	Severe-Lymphoid-NK-Treg\|Severe / Condition, Lineage, Cell class and cell subclass	CAD ZFAT POLH NVL MCM4 DDX11 GOLGA7B	6.04e-06	190	161	7	e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYH9 VWA1 TEK DENND3 AFAP1L1 RFLNB	6.47e-06	192	161	7	9d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYH9 VWA1 TEK DENND3 AFAP1L1 RFLNB	6.47e-06	192	161	7	042391162df2e3d0027688dd14163c4c6821afe0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYH9 VWA1 TEK DENND3 AFAP1L1 RFLNB	6.47e-06	192	161	7	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYH9 VWA1 TEK DENND3 AFAP1L1 RFLNB	6.47e-06	192	161	7	71b0bfee0461ff64cef35881db3959c517e9731b
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYH9 VWA1 TEK DENND3 AFAP1L1 RFLNB	6.47e-06	192	161	7	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MYH9 VWA1 TEK DENND3 AFAP1L1 RFLNB	6.47e-06	192	161	7	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 DNAH10 FRMPD2 MTSS1 ADGRV1 ODAD2 HYDIN	6.69e-06	193	161	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	EPYC STAC DNAH14 PPM1H AFAP1L1 TMEM132C LPCAT2	6.69e-06	193	161	7	826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCell	Control-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	FLT1 ARHGAP26 MTSS1 STK10 RFLNB VCAN MAP4K4	6.92e-06	194	161	7	f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 AXL PODXL2 VCAN DOCK7 C3 GFPT2	7.40e-06	196	161	7	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 AXL DENND3 LPCAT2 C3 HSD17B11 IGSF21	7.65e-06	197	161	7	50f994e0d4e69019ec92e164edf3e4e951333766
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	8.17e-06	199	161	7	2498237b9e895ca4826a3378d9d40989968df72b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	8.17e-06	199	161	7	542ec45c931b40738df1f3777b00c83be33a514a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PTTG1 CENPC ZGRF1 TTK DDX11 CKAP2 POLQ	8.17e-06	199	161	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PTTG1 CENPC ZGRF1 TTK DDX11 CKAP2 POLQ	8.45e-06	200	161	7	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HTRA1 DSCAM MTSS1 TEK TMEM132C VCAN IGSF21	8.45e-06	200	161	7	ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DSCAM AXL DENND3 LPCAT2 C3 IGSF21	2.48e-05	159	161	6	31ec8222c766cb614e1cf27f74ee9d99489eca5c
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1H STK10 KIDINS220 RFLNB CELSR2 LRP5	2.66e-05	161	161	6	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HTRA1 AXL TEK C3 GFPT2 HYDIN	2.76e-05	162	161	6	56f1789e69a6cb29956e46aba92b290847327c1f
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	KDM5B CCDC175 VWA1 ASXL3 PRL CDK6	3.27e-05	167	161	6	cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPD2 PTTG1 FLT1 RCCD1 AFAP1L1 NOTCH3	3.38e-05	168	161	6	c7021748003e5949f7caf7b3291c5bad294948c1
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTTG1 ZGRF1 TTK DDX11 CKAP2 POLQ	3.50e-05	169	161	6	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM MYH9 FMO5 RFLNB LPCAT2 C3	3.74e-05	171	161	6	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO19 DENND3 MTERF2 HECTD2 DDX3Y HSD17B11	3.74e-05	171	161	6	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM MYH9 FMO5 RFLNB LPCAT2 C3	3.74e-05	171	161	6	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTTG1 ZGRF1 TTK PPP4R4 CKAP2 POLQ	3.74e-05	171	161	6	c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTTG1 KRT13 ACOX2 AFAP1L1 CELSR2 POLQ	3.74e-05	171	161	6	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	RSV-Healthy-2\|Healthy / Virus stimulation, Condition and Cluster	MYO7A WRN TTK CKAP2 POLQ NSMCE4A	4.25e-05	175	161	6	c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCell	RSV-Healthy-2\|RSV / Virus stimulation, Condition and Cluster	MYO7A WRN TTK CKAP2 POLQ NSMCE4A	4.25e-05	175	161	6	0e97189585b7afaf3bd622c3ef10c86412393829
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT1 VWA1 TEK AFAP1L1 RFLNB HAS3	4.25e-05	175	161	6	7be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPC LIN54 TTK STAC CKAP2 NOTCH3	4.39e-05	176	161	6	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTTG1 FLT1 ZGRF1 MCM4 CKAP2 POLQ	4.53e-05	177	161	6	73ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 RAB17 MCM4 TEK AFAP1L1 CELSR2	4.53e-05	177	161	6	0e74980a7686c31fcf1476b8f19a3392541df240
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A AXL ZGRF1 MTSS1 CKAP2 SULT4A1	4.67e-05	178	161	6	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 ARHGAP26 VWA1 TEK AFAP1L1 RFLNB	4.82e-05	179	161	6	8f9e538c822940785130297712b75131812a4603
ToppCell	facs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 ODAD2 MYCBPAP ACOX2 WDR93 HYDIN	4.97e-05	180	161	6	cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CCDC175 VWA1 ACOX2 AFAP1L1 LRP5 CDK6	4.97e-05	180	161	6	2694f5deaed551c53e74d8a9fbd41d3734bb9f37
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTTG1 ZGRF1 TTK DDX11 CKAP2 POLQ	4.97e-05	180	161	6	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CCDC175 VWA1 ACOX2 AFAP1L1 LRP5 CDK6	4.97e-05	180	161	6	ef0de602fc8ccfd32a06978ac0100afe0ce1beeb
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL GATM MCM4 TTK CKAP2 POLQ	5.29e-05	182	161	6	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SYNM SLC38A4 TEK BCR AFAP1L1 STOX2	5.45e-05	183	161	6	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	DNAH10 MCM4 TTK PPP2R1B RFLNB POLQ	5.62e-05	184	161	6	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	DNAH10 MCM4 TTK PPP2R1B RFLNB POLQ	5.62e-05	184	161	6	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNM PODXL2 VWA1 MYCBPAP VCAN IGSF21	5.79e-05	185	161	6	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTTG1 ZGRF1 POLH TTK CKAP2 POLQ	5.79e-05	185	161	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 CCDC175 ODAD2 HYDIN	5.79e-05	185	161	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93	5.79e-05	185	161	6	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AXL GATM BCR SULT1A2 NOTCH3 CDK6	5.79e-05	185	161	6	b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell\|TCGA-Uvea / Sample_Type by Project: Shred V9	MYO19 MCM4 TEP1 PAPSS2 DENND3 ATP5F1B	5.96e-05	186	161	6	e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93	6.14e-05	187	161	6	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTTG1 ZGRF1 POLH TTK CKAP2 POLQ	6.14e-05	187	161	6	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH10 FRMPD2 ODAD2 MYCBPAP WDR93 HYDIN	6.14e-05	187	161	6	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	droplet-Fat-SCAT-30m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 SYNM TEK AFAP1L1 RFLNB NOTCH3	6.33e-05	188	161	6	e901a9bdf00b8e91806f445af66647373bf62661
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EFCAB13 ADGRV1 DNAH14 PPM1H STOX2 HYDIN	6.33e-05	188	161	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	droplet-Fat-SCAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 SYNM TEK AFAP1L1 RFLNB NOTCH3	6.33e-05	188	161	6	5cf060bb8adaefa9964187195d67993c1248ef47
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 DNAH10 FRMPD2 ODAD2 WDR93 HYDIN	6.33e-05	188	161	6	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
Disease	CADASIL Syndrome	HTRA1 NOTCH3	2.71e-05	2	154	2	C0751587
Disease	CADASILM	HTRA1 NOTCH3	2.71e-05	2	154	2	C1449626
Disease	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy	HTRA1 NOTCH3	2.71e-05	2	154	2	cv:C0751587
Disease	age related macular degeneration 7 (is_implicated_in)	HTRA1 C3	2.71e-05	2	154	2	DOID:0110019 (is_implicated_in)
Disease	DEAFNESS, AUTOSOMAL DOMINANT 1 (disorder)	MYO1C DIAPH1	8.09e-05	3	154	2	C1852282
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX11 DDX11L8	8.09e-05	3	154	2	DOID:0060535 (implicated_via_orthology)
Disease	Kuhnt-Junius degeneration (is_implicated_in)	FLT1 HTRA1 C3	8.98e-05	17	154	3	DOID:10873 (is_implicated_in)
Disease	Transitional cell carcinoma of bladder	FLT1 BCR	1.61e-04	4	154	2	C0279680
Disease	urinary potassium to creatinine ratio	CYP21A2 GATM	4.00e-04	6	154	2	EFO_0009882
Disease	Autosomal dominant nonsyndromic hearing loss	MYH9 MYO7A DIAPH1	4.61e-04	29	154	3	cv:C5779548
Disease	sensorineural hearing loss (is_implicated_in)	MYH9 MYO7A DIAPH1	6.78e-04	33	154	3	DOID:10003 (is_implicated_in)
Disease	Nonsyndromic genetic hearing loss	MYH9 MYO7A TPRN DIAPH1	6.84e-04	76	154	4	cv:C5680182
Disease	lactase-phlorizin hydrolase measurement	LCT R3HDM1	7.42e-04	8	154	2	EFO_0801753
Disease	glycine measurement	CYP21A2 EFCAB13 ADGRV1 PPM1H UNC80	7.79e-04	137	154	5	EFO_0009767
Disease	alpha-1-antitrypsin measurement	PPP4R4 CELSR2	9.51e-04	9	154	2	EFO_0008327
Disease	Hereditary hearing loss and deafness	MYH9 MYO7A TPRN SURF1 DIAPH1	1.04e-03	146	154	5	cv:C0236038
Disease	response to radiation, Abnormality of the urinary system	STAC STOX2	1.18e-03	10	154	2	GO_0009314, HP_0000079
Disease	age-related macular degeneration, disease progression measurement	HTRA1 STOX2 C3	1.28e-03	41	154	3	EFO_0001365, EFO_0008336
Disease	Malignant neoplasm of breast	FLT1 MYH9 STARD8 ATP7B RCCD1 POLH EFCAB13 TEK RIF1 WDCP SURF1 MROH7 ADGRF4 NOTCH3	1.54e-03	1074	154	14	C0006142
Disease	hearing impairment	MYO7A TPRN ADGRV1 DIAPH1	1.76e-03	98	154	4	C1384666
Disease	cholesterol in medium LDL measurement	EFCAB13 CELSR2 DOCK7	2.15e-03	49	154	3	EFO_0022224
Disease	Impaired cognition	HTRA1 NOTCH3	2.36e-03	14	154	2	C0338656
Disease	total lipids in medium LDL	EFCAB13 CELSR2 DOCK7	2.55e-03	52	154	3	EFO_0022180
Disease	cardiovascular disease	DCUN1D5 LIN54 EFCAB13 WRN ODAD2 CELSR2 DOCK7 CDK6	2.85e-03	457	154	8	EFO_0000319
Disease	triglycerides in medium VLDL measurement	DNAH10 CELSR2 DOCK7	3.00e-03	55	154	3	EFO_0022155
Disease	Chromosome Aberrations	SULT1A2 CDK6	3.10e-03	16	154	2	C0008625
Disease	Autosome Abnormalities	SULT1A2 CDK6	3.10e-03	16	154	2	C0004403
Disease	serum gamma-glutamyl transferase measurement	UNC119B SYT12 TRPM7 NUP210L AXL CYP21A2 UBE4A CELSR2 C3 IGSF21 EPHA1 CDK6	3.14e-03	914	154	12	EFO_0004532
Disease	Dementia	HTRA1 NOTCH3	3.50e-03	17	154	2	C0497327
Disease	low density lipoprotein cholesterol measurement, body fat percentage	DNAH10 EFCAB13	3.50e-03	17	154	2	EFO_0004611, EFO_0007800
Disease	Van Buchem disease	FLT1 LRP5	3.50e-03	17	154	2	C0432272
Disease	glomerulonephritis (implicated_via_orthology)	AXL C3	3.50e-03	17	154	2	DOID:2921 (implicated_via_orthology)
Disease	pain	HTRA1 CYP21A2 INTS3 CELSR2 RABGAP1L	3.74e-03	196	154	5	EFO_0003843
Disease	lean body mass	ZFAT TRPM7 CYP21A2 ADGRV1 VCAN HSD17B11 CDK6	3.87e-03	379	154	7	EFO_0004995
Disease	Age-related macular degeneration	HTRA1 C3	3.92e-03	18	154	2	cv:C0242383
Disease	Tourette syndrome, schizophrenia	DNAH10 MYO19	3.92e-03	18	154	2	EFO_0004895, MONDO_0005090
Disease	Hemangiosarcoma	FLT1 TEK	3.92e-03	18	154	2	C0018923
Disease	serum metabolite measurement	GPD2 UNC119B CYP21A2 GATM TEK PAPSS2 STAC SULT1A2 CELSR2 RABGAP1L DOCK7 PRKCD	4.10e-03	945	154	12	EFO_0005653
Disease	Cerebrovascular accident	PRPF8 NOTCH3 CDK6	4.21e-03	62	154	3	C0038454
Disease	cutaneous melanoma, hair color	ADGRV1 MED13L BCR	4.21e-03	62	154	3	EFO_0000389, EFO_0003924
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 HYDIN	4.37e-03	19	154	2	DOID:10908 (implicated_via_orthology)
Disease	pulmonary non-tuberculous mycobacterial infection	FLT1 SCAP	4.37e-03	19	154	2	MONDO_0018469
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	FLT1 ARHGAP26 CELSR2	4.40e-03	63	154	3	EFO_0001645, EFO_0004792
Disease	cholesterol in large VLDL measurement	DNAH10 CELSR2 DOCK7	4.81e-03	65	154	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	DNAH10 CELSR2 DOCK7	4.81e-03	65	154	3	EFO_0022230
Disease	serum homoarginine measurement	CYP21A2 GATM	4.83e-03	20	154	2	EFO_0005421
Disease	Disorder of eye	MYO7A ADGRV1 PRPF8 VCAN LRP5	5.20e-03	212	154	5	C0015397

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGENLPIEDRETIIM	PPP2R1B	321	P30154
EREDQLVPGQLVAML	EPHA1	716	P21709
DIGVEPENVVMLVLA	DCUN1D4	131	Q92564
LPMVVVRVELLSGEI	ACOX2	291	Q99424
LDNPIQVEMGEELVL	PRMT9	816	Q6P2P2
EQIEVGPLVTSMEIL	VCAN	491	P13611
PRMELRSVGDIEQEL	BCR	21	P11274
REEQVPMELVQRGDI	ATP7B	816	P35670
TEDILGMVQIPRQEL	ADGRF4	266	Q8IZF3
VRRPGMEIAEIMIEE	ADGRV1	3891	Q8WXG9
VEEDVGLIMIPVVRL	ADGRV1	4411	Q8WXG9
PNILRLESEETMVLE	C3	31	P01024
EEGMPLSTIREVAVL	CDK6	51	Q00534
VLMDVSRRENGEILP	CELSR2	2361	Q9HCU4
ETEEGILLLVRAMDP	DIAPH1	236	O60610
TLEPEEVVNRLMHGI	HSD17B11	236	Q8NBQ5
AEQAPELMRLISEIL	DENND3	611	A2RUS2
DVDVVMGDPVLLRSV	CAMSAP3	416	Q9P1Y5
DIGVEPENIIMLVLA	DCUN1D5	76	Q9BTE7
GEFTPEMQLRIRQEI	ASXL3	326	Q9C0F0
LGRIMNVIGEPIDER	ATP5F1B	141	P06576
GAQPIEEMRHTIVDI	CKAP2	491	Q8WWK9
RHRALEVIPEIMQGI	MROH7	736	Q68CQ1
VLEITELPDGITRME	R3HDM1	986	Q15032
PRLLEALQGLVMAEV	RCCD1	201	A6NED2
LEEELHPGEVLVMLV	RAB17	116	Q9H0T7
ILEAEPIRMLEIEGE	REC8	196	O95072
PDETLRSGELLNMIV	INTS3	751	Q68E01
TEPTVQIGRLLMEEL	INTS9	126	Q9NV88
LEDIREELTMAILAP	NVL	586	O15381
VQLMGLLRTLVDPEN	PPP4R3A	446	Q6IN85
ILEDLPIQSGDMLII	YOD1	106	Q5VVQ6
AEQATRIVILGPEVM	MORN1	211	Q5T089
LEVIGRLPDMEMVIN	POGLUT1	116	Q8NBL1
VVPTQDVLSMLGDIR	PODXL2	456	Q9NZ53
PEDIDQLITISGMVI	MCM4	276	P33991
LLDDGVINMSIPIVL	PAPSS2	286	O95340
AIIILPNTDGMELLV	MAP4K4	1121	O95819
EMEGIRETSQVILRP	KIDINS220	1701	Q9ULH0
AEEALPRIVELMGRE	GPD2	566	P43304
LLPEEIMDTGITLVD	LIN54	11	Q6MZP7
LVGQRLPLMAEVSET	MED13L	601	Q71F56
AMPRDILIVVGNEII	GATM	166	P50440
GRVIQIVLMRAAEEP	PRKCD	66	Q05655
SLLGLPEDVLLEMVQ	MYO19	336	Q96H55
MEGLLVPEETLRELL	ELF4	556	Q99607
LTDPVERGMRVIEIS	GOLGA7B	121	Q2TAP0
MRVILILDPAISGNE	MGAM	2206	O43451
SNALMLLRPEEVEIL	HECTD2	646	Q5U5R9
ASRDVIIDQLPDLMG	LRP5	576	O75197
PGIDLTRVLAEMREQ	KRT13	266	P13646
RGRILIMDVIEVVPE	CPSF1	1136	Q10570
ALLLGIRDSMEPVVE	CYP21A2	126	P08686
IEIATVMPSGNRELL	EPYC	56	Q99645
MPTVLGVLLLDQREI	OR51B4	76	Q9Y5P0
MLRPVIEEEISMLGE	MTSS1	201	O43312
MTEIRRSLGEIPIVE	COPB1	476	P53618
DMPENSRVLRVVLLG	ERAL1	106	O75616
GELVMVPNVEAILED	NOL6	1111	Q9H6R4
RELAPEVIGSVVMLE	NOTCH3	1571	Q9UM47
IDRLQDAGIEPMATL	LCT	481	P09848
VEGLDPDNVRAMVRL	GPKOW	261	Q92917
VLEGLREDMLETLVP	GPKOW	401	Q92917
DVELPQLAEMRIRLE	KDM5B	901	Q9UGL1
IPEEEQMGLLRVISG	MYH9	331	P35579
EMLETGPEAERLEQL	DDX11	176	Q96FC9
DMVVTEVVEPVRFLL	RABGAP1L	396	Q5R372
VPVLEERMQGLLREG	MTERF2	296	Q49AM1
VRNLMAEALGIPVTD	LPCAT2	306	Q7L5N7
ALERVPSMELGRLEI	MYO15B	416	Q96JP2
ELVLERVPAELNGSM	IGSF21	396	Q96ID5
MLSIGIEEVFDILPL	HYDIN	1321	Q4G0P3
VVRRGNEDIMITVIP	HTRA1	461	Q92743
LETVRFPLMEAEVLQ	KLHL22	241	Q53GT1
EEIILTPIEVAIEDM	DOCK7	1986	Q96N67
RQVLEELTELPVMVE	GFPT2	386	O94808
AMDEELERLLAQVPG	CSTPP1	266	Q9H6J7
LLVVPVLGRMSDQTD	BTAF1	1186	O14981
SLEGLRLLVEQESPM	CCDC175	751	P0C221
ETREIILMDLVRPQD	CENPC	831	Q03188
LEQMLLELGVELSPT	DMAP1	341	Q9NPF5
RVELGVPEVLMFETE	GAS2L1	111	Q99501
VPEVLMFETEDLVLR	GAS2L1	116	Q99501
EELDMAGVQSLVPRL	FRMPD2	906	Q68DX3
MEELADLVGVRPNLL	FMO5	436	P49326
ELLEVMDQLRRLPSG	POLQ	386	O75417
EMLETGPEAERLEQL	DDX11L8	176	A8MPP1
LRALEPLEGLETMRQ	MPG	181	P29372
TLVTEMQEELLILGP	DNAH14	2271	Q0VDD8
LDSMGIPINREILEE	EFCAB13	246	Q8IY85
AQGEAMRAVLIPIRE	FAM98C	251	Q17RN3
PDVLTIMLQLFDEGR	CLPB	461	Q9H078
IEMLRVLEEDPQVGG	HAS3	226	O00219
VTELMRLLGPSQERE	HAUS4	121	Q9H6D7
LDMGFEPQIRRIVEQ	DDX3Y	351	O15523
EIKLEMPIISVEGEV	DNAH10	221	Q8IVF4
EIVPLVLRGHLMDIE	SCAP	766	Q12770
EEAIVILQGQPEMLL	CFAP47	216	Q6ZTR5
VRVEDVAAELGMPTL	JADE3	411	Q92613
ADVEIGQIIEIPIAM	NUP210L	556	Q5VU65
LSGVPLMILDEEREL	PTTG1	141	O95997
LVTEVRGMQEAPEAI	PRL	126	P01236
DIPRAQLLIEERDTM	DSCAM	1661	O60469
VLDPRDIISGVEMQV	VARS2	666	Q5ST30
FMRVSLLPDEQIVGI	SYT12	191	Q8IV01
MEDLQELTIIERPVR	PPP4R4	21	Q6NUP7
DLVGIVPLAMDTEIL	TMEM132C	426	Q8N3T6
EVIGQLEETLPERMR	SYNM	951	O15061
RLNGVLMEVEEPEVL	NBPF9	1031	P0DPF3
MVGRLSLQDVPELVD	RFLNB	1	Q8N5W9
IVRLIEQAPIQMGEE	RIF1	166	Q5UIP0
NLIPIEALLQGEEEM	MTF1	731	Q14872
IVDLGGLPIMVNILD	ODAD2	531	Q5T2S8
LLRPQEETVAAIMDI	ARHGAP26	536	Q9UNA1
LDTGEQLMVPVEVLE	SLC25A41	71	Q8N5S1
LEPLVDIETINMRLD	MSH4	356	O15457
MGVNPLEAEELIRDE	NSMCE4A	171	Q9NXX6
IGLVISPLISLMEDQ	WRN	591	Q14191
PDLQLTVGAVIVEEM	POLH	186	Q9Y253
VDLIGMVRLTETRQP	SURF1	201	Q15526
VIEPGLLFEIIEMLQ	IARS2	906	Q9NSE4
ELPEVIRAFMGLEEN	SLC38A4	176	Q969I6
MLDLEVVPERSLGNE	PHAF1	1	Q9BSU1
AAVPRTIGAELMELV	NCKIPSD	306	Q9NZQ3
LLRAQVLEALMPGVE	STARD8	891	Q92502
RIELEEMGPSLDLVL	RPF2	211	Q9H7B2
MDRGQVLEQLLPELT	AFAP1L1	1	Q8TED9
IQEVRDMVITRPDIG	CLVS2	31	Q5SYC1
QEIDDVIGQVRRPEM	CYP2D7	351	A0A087X1C5
EIRDIILGMEISAPS	PRPF8	2006	Q6P2Q9
IVQELRGSILDAMRP	VWA1	201	Q6PCB0
MEEGVNVDEIIIPLR	ZFAT	36	Q9P243
VLPIVHLMEDGEVRE	UNC80	1851	Q8N2C7
MAVVLPAVVEELLSE	ZSWIM7	1	Q19AV6
RVPVDRVILLGQSMD	TEP1	776	Q99973
EIGLMNIDEQLPVLE	SULT4A1	76	Q9BR01
AIIIRNGEIIPMSSE	PPM1H	291	Q9ULR3
GIPDVVVEMAEADLR	STOML1	346	Q9UBI4
EMEIIRRINPDLTVE	STOX2	311	Q9P2F5
VGRSLPEETVDLMVE	SULT1A2	211	P50226
VVQHLPLELMDGVVR	USP35	236	Q9P2H5
IMLELDRGLTEPQIQ	STK10	121	O94804
NEDLEMRPGDIITLL	STAC	301	Q99469
ERRLMVVGDAPESIQ	VPS16	286	Q9H269
PRMEEVTLSEVVRVG	FAM170A	156	A1A519
EFPQLSEDVIRLMIE	UNC119B	206	A6NIH7
TPEVLMDIGLRQEVT	AXL	376	P30530
VLQELLMGVLTPERT	MYCBPAP	566	Q8TBZ2
EREGIQRMTPKIVDL	TEK	341	Q02763
ALATRVIMGEEVEPV	CAD	1236	P27708
VMETIPLGDLQARAL	TPRN	306	Q4KMQ1
ERGAVPLEMLEIALR	TTK	171	P33981
EILIAPVDEMGIIRL	WDR93	156	Q6P2C0
LMNGVTEIERSPLLE	ZGRF1	1896	Q86YA3
LILDEEVRTFPEVMI	UBE4A	256	Q14139
MGTIPLIESLLDIRN	TMTC3	306	Q6ZXV5
LIVREIMLEEEPSIT	WDCP	426	Q9H6R7
EIPEIIHMTEGRELV	FLT1	141	P17948
DEIIPTNTLEEIMLA	TRPM7	1736	Q96QT4
IEMPEELDISQLRGT	USP5	591	P45974
RMVNVLEPDITVIVG	TMPPE	231	Q6ZT21
RMLSLLVVDVGNPEE	GEMIN4	831	P57678
MALQVELVPTGEIIR	MYO1C	1	O00159
GSEMILERLLNLVPT	MYO7A	1401	Q13402