Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dihydropyrimidinase activity	DPYSL2 DPYSL3 CRMP1	1.69e-05	6	191	3	GO:0004157
GeneOntologyCellularComponent	periciliary membrane compartment	USH2A KIFAP3 RP2	1.49e-05	6	192	3	GO:1990075
Domain	Hydantoinase/dihydroPyrase	DPYSL2 DPYSL3 CRMP1	2.12e-05	6	193	3	IPR011778
Domain	-	DPYSL2 DPYSL3 CRMP1	5.86e-05	8	193	3	2.30.40.10
Domain	Calsequestrin_CS	CASQ1 CASQ2	1.06e-04	2	193	2	IPR018233
Domain	Calsequestrin	CASQ1 CASQ2	1.06e-04	2	193	2	PF01216
Domain	CALSEQUESTRIN_1	CASQ1 CASQ2	1.06e-04	2	193	2	PS00863
Domain	CALSEQUESTRIN_2	CASQ1 CASQ2	1.06e-04	2	193	2	PS00864
Domain	ATM/Tel1	SMG1 ATM	1.06e-04	2	193	2	IPR015519
Domain	Amidohydro_1	DPYSL2 DPYSL3 CRMP1	1.24e-04	10	193	3	PF01979
Domain	Metal-dep_hydrolase_composite	DPYSL2 DPYSL3 CRMP1	1.24e-04	10	193	3	IPR011059
Domain	Amidohydro-rel	DPYSL2 DPYSL3 CRMP1	1.69e-04	11	193	3	IPR006680
Domain	calpain_III	CAPN1 CAPN2 CAPN6	2.23e-04	12	193	3	SM00720
Domain	C2_III	CAPN1 CAPN2 CAPN6	2.23e-04	12	193	3	IPR033883
Domain	Calpain_III	CAPN1 CAPN2 CAPN6	2.23e-04	12	193	3	IPR022683
Domain	Calpain_III	CAPN1 CAPN2 CAPN6	2.88e-04	13	193	3	PF01067
Domain	Calpain_domain_III	CAPN1 CAPN2 CAPN6	2.88e-04	13	193	3	IPR022682
Domain	C2_dom	INPP4A NEDD4 C2CD2L OSBPL6 ESYT1 CAPN6 SYTL1 RIMS2	3.11e-04	164	193	8	IPR000008
Domain	Calpain_cysteine_protease	CAPN1 CAPN2 CAPN6	3.64e-04	14	193	3	IPR022684
Domain	Peptidase_C2	CAPN1 CAPN2 CAPN6	4.51e-04	15	193	3	PF00648
Domain	CysPc	CAPN1 CAPN2 CAPN6	4.51e-04	15	193	3	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN1 CAPN2 CAPN6	4.51e-04	15	193	3	IPR001300
Domain	CALPAIN_CAT	CAPN1 CAPN2 CAPN6	4.51e-04	15	193	3	PS50203
Domain	Adenylate_cyclase-assoc_CAP_C	CAP2 RP2	6.29e-04	4	193	2	IPR013912
Domain	Calsequestrin	CASQ1 CASQ2	6.29e-04	4	193	2	IPR001393
Domain	Znf_FYVE_PHD	SPIRE2 KMT2C KDM5A KMT2D BAZ2A ZFYVE26 RIMS2	8.51e-04	147	193	7	IPR011011
Domain	-	INPP4A NEDD4 C2CD2L ESYT1 CAPN6 SYTL1 RIMS2	8.85e-04	148	193	7	2.60.40.150
Domain	FYrich_C	KMT2C KMT2D	1.04e-03	5	193	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	1.04e-03	5	193	2	IPR003888
Domain	FYRC	KMT2C KMT2D	1.04e-03	5	193	2	SM00542
Domain	FYRN	KMT2C KMT2D	1.04e-03	5	193	2	SM00541
Domain	BAGE	BAGE2 BAGE3	1.04e-03	5	193	2	IPR012530
Domain	BAGE	BAGE2 BAGE3	1.04e-03	5	193	2	PF08180
Domain	CAP/MinC_C	CAP2 RP2	1.04e-03	5	193	2	IPR016098
Domain	CARP_motif	CAP2 RP2	1.04e-03	5	193	2	IPR006599
Domain	-	CAP2 RP2	1.04e-03	5	193	2	2.160.20.70
Domain	C-CAP_CF_C-like	CAP2 RP2	1.04e-03	5	193	2	IPR017901
Domain	CARP	CAP2 RP2	1.04e-03	5	193	2	SM00673
Domain	FATC	SMG1 ATM	1.04e-03	5	193	2	PF02260
Domain	FYRN	KMT2C KMT2D	1.04e-03	5	193	2	PF05964
Domain	FYRC	KMT2C KMT2D	1.04e-03	5	193	2	PF05965
Domain	FYRC	KMT2C KMT2D	1.04e-03	5	193	2	PS51543
Domain	FYRN	KMT2C KMT2D	1.04e-03	5	193	2	PS51542
Domain	C_CAP_COFACTOR_C	CAP2 RP2	1.04e-03	5	193	2	PS51329
Domain	EFh	EPS15 DST PLS3 CAPN1 CAPN2 MACF1 RASEF	1.30e-03	158	193	7	SM00054
Domain	fn3	EPHB4 AXL PTPRH USH2A OBSL1 ROS1 LRIT1	1.50e-03	162	193	7	PF00041
Domain	-	DST MACF1	1.55e-03	6	193	2	3.90.1290.10
Domain	GAR	DST MACF1	1.55e-03	6	193	2	PS51460
Domain	GAS2	DST MACF1	1.55e-03	6	193	2	PF02187
Domain	FAT	SMG1 ATM	1.55e-03	6	193	2	PS51189
Domain	FATC	SMG1 ATM	1.55e-03	6	193	2	PS51190
Domain	FATC_dom	SMG1 ATM	1.55e-03	6	193	2	IPR003152
Domain	-	DST MACF1	1.55e-03	6	193	2	3.30.920.20
Domain	PIK_FAT	SMG1 ATM	1.55e-03	6	193	2	IPR014009
Domain	GAS_dom	DST MACF1	1.55e-03	6	193	2	IPR003108
Domain	GAS2	DST MACF1	1.55e-03	6	193	2	SM00243
Domain	FATC	SMG1 ATM	1.55e-03	6	193	2	SM01343
Domain	ACTININ_2	DST PLS3 MACF1	1.65e-03	23	193	3	PS00020
Domain	ACTININ_1	DST PLS3 MACF1	1.65e-03	23	193	3	PS00019
Domain	Actinin_actin-bd_CS	DST PLS3 MACF1	1.65e-03	23	193	3	IPR001589
Domain	Peptidase_M12B_ADAM-TS	ADAMTS19 ADAMTS13 ADAMTS8	1.87e-03	24	193	3	IPR013273
Domain	Metal_Hydrolase	DPYSL2 DPYSL3 CRMP1	1.87e-03	24	193	3	IPR032466
Domain	Plectin	DST MACF1	2.16e-03	7	193	2	PF00681
Domain	Trimer_CC	CORO1B CORO6	2.16e-03	7	193	2	IPR015049
Domain	DUF1899	CORO1B CORO6	2.16e-03	7	193	2	IPR015048
Domain	Trimer_CC	CORO1B CORO6	2.16e-03	7	193	2	PF08954
Domain	DUF1899	CORO1B CORO6	2.16e-03	7	193	2	PF08953
Domain	Plectin_repeat	DST MACF1	2.16e-03	7	193	2	IPR001101
Domain	Coronin	CORO1B CORO6	2.16e-03	7	193	2	IPR015505
Domain	DUF1899	CORO1B CORO6	2.16e-03	7	193	2	SM01166
Domain	PLEC	DST MACF1	2.16e-03	7	193	2	SM00250
Domain	Pkinase_Tyr	EPHB4 AXL FLT4 ARAF GUCY2D ROS1	2.24e-03	129	193	6	PF07714
Domain	EF_Hand_1_Ca_BS	EPS15 DST PLS3 CAPN1 CAPN2 MACF1 RASEF	2.32e-03	175	193	7	IPR018247
Domain	THIOL_PROTEASE_CYS	CAPN1 CAPN2 CAPN6	2.37e-03	26	193	3	PS00139
Domain	Znf_PHD	ASXL1 KMT2C KDM5A KMT2D BAZ2A	2.54e-03	91	193	5	IPR001965
Domain	ADAM_Cys-rich	ADAMTS19 ADAMTS13 ADAMTS8	2.65e-03	27	193	3	IPR006586
Domain	THIOL_PROTEASE_ASN	CAPN1 CAPN2 CAPN6	2.65e-03	27	193	3	PS00640
Domain	ACR	ADAMTS19 ADAMTS13 ADAMTS8	2.65e-03	27	193	3	SM00608
Domain	THIOL_PROTEASE_HIS	CAPN1 CAPN2 CAPN6	2.65e-03	27	193	3	PS00639
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 EPHB4 NACA2 SPIRE2 TBKBP1 KIF26A APBB3 PFAS ATG2A ARHGEF11 MAST2 C2CD2L KMT2C DST SBF1 MFN2 DPH2 ESYT1 GEMIN5 TBC1D25 CORO1B TEP1 GBA2 KCNH3 KMT2D ZFYVE26 TJP3	1.71e-10	1105	196	27	35748872
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EPHB4 DCAF1 EPS15 AFTPH PTDSS1 PFAS MCCC2 NCAPG2 SBF1 RAB3GAP2 PLS3 VCP DPH2 TBC1D15 DYNC2H1 ESYT1 MYO18A OBSL1 PON2 MRPL28 COL18A1 BAZ2A MTIF2 TIMM50 CNDP2 MACF1 ELP2 WDR41 ATM CXADR	1.43e-09	1487	196	30	33957083
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DCAF1 TBKBP1 MAST2 DST ESYT1 ANGEL1 LTN1 MACF1 RIMS2	6.37e-09	101	196	9	9872452
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TBKBP1 AFTPH KIF1B MCCC2 ATG2A ARHGEF11 MAST2 LENG8 CPLANE1 PLS3 DPYSL2 DPYSL3 ESYT1 CORO1B FHIP2A ARAF TIMM50 RASEF TBC1D23 RINL BORA	1.87e-08	853	196	21	28718761
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LDLRAP1 KIF1B ANKS1B APBB3 UBA7 DST MCRS1 PJA1 ZNF606 CAP2 VCP DPYSL2 WASHC4 KDM5A OBSL1 XPC ADAMTS8 CREBBP CRMP1 ZNF7 ZNF34 SNRNP48 MTIF2 MACF1 ATM TBC1D23	1.89e-08	1285	196	26	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DCAF1 ZHX3 ASXL1 SLK KIF1B GON4L NEDD4 C2CD2L RAB3GAP2 MFN2 OBSL1 FHIP2A BAZ2A MACF1	9.27e-08	407	196	14	12693553
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EPS15 AFTPH PTDSS1 GON4L ARHGEF11 C2CD2L LENG8 KMT2C DST SBF1 ATXN2 MCRS1 PLS3 CERS2 TDRKH KDM5A ESYT1 RPP38 GEMIN5 XPC KRR1 ARAF MRM3 COL18A1 BAZ2A LTN1 MACF1	1.02e-07	1497	196	27	31527615
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DCAF1 NES PFAS MCCC2 NCAPG2 DST SBF1 ALOX12B VCP DPYSL2 WASHC4 ESYT1 CAPN1 CAPN2 RPP38 GEMIN5 XPC CORO1B KRR1 CREBBP NCCRP1 BAZ2A LTN1 TIMM50 MACF1	2.03e-07	1353	196	25	29467282
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF1 TPRN MAST2 C2CD2L PRPF40B MCRS1 VCP TDRKH KDM5A ANGEL1 RPP38 OBSL1 XPC TEP1 CREBBP SIRT5 ARAF BAZ2A MTIF2 LTN1 TIMM50 MACF1	3.96e-07	1116	196	22	31753913
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 ZHX3 ASXL1 C2CD2L KMT2C DST RAB3GAP2 CACNA1G OBSL1 MACF1	6.73e-07	225	196	10	12168954
Pubmed	Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.	DPYSL2 DPYSL3 CRMP1	7.02e-07	4	196	3	10664068
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C CREBBP KMT2D	7.02e-07	4	196	3	28398509
Pubmed	The Ulip family phosphoproteins--common and specific properties.	DPYSL2 DPYSL3 CRMP1	7.02e-07	4	196	3	9652388
Pubmed	Functional proteomics mapping of a human signaling pathway.	SMG1 EPS15 INPP4A TPRN NEDD4 MTMR11 DST CAP2 FLT4 WASHC4 XPC CREBBP KMT2D MACF1 SPRTN	1.51e-06	591	196	15	15231748
Pubmed	Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.	DPYSL2 DPYSL3 CRMP1	1.75e-06	5	196	3	16611631
Pubmed	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.	DPYSL2 DPYSL3 CRMP1	1.75e-06	5	196	3	8973361
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	EPS15 KMT2C DST RAB3GAP2 DPYSL2 WASHC4 DYNC2H1 GBA2 CRMP1 MACF1 ARHGAP28	2.44e-06	322	196	11	26514267
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ASXL1 TBKBP1 RILP MYSM1 DST SBF1 VCP CAPN2 CREBBP MACF1 SPRTN	3.27e-06	332	196	11	37433992
Pubmed	New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile.	KMT2C BAGE2 BAGE3	3.48e-06	6	196	3	12461691
Pubmed	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.	DPYSL2 DPYSL3 CRMP1	3.48e-06	6	196	3	10956643
Pubmed	BAGE genes generated by juxtacentromeric reshuffling in the Hominidae lineage are under selective pressure.	KMT2C BAGE2 BAGE3	3.48e-06	6	196	3	12676563
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	EPS15 MCCC2 LENG8 RAB3GAP2 DPYSL2 TBC1D15 ESYT1 CAPN2 PON2 MRPL28 LTN1 TIMM50 ELP2 WDR41	4.06e-06	560	196	14	35241646
Pubmed	A human MAP kinase interactome.	KIF26A TRIM21 ARHGEF11 LENG8 KMT2C DST CPLANE1 CAP2 NUP98 MYO18A CREBBP ARAF MACF1	4.39e-06	486	196	13	20936779
Pubmed	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.	DCAF1 EPS15 MTMR11 SBF1 OSBPL6 CAPN2 TIMM50 BORA	5.20e-06	167	196	8	25659891
Pubmed	Structure and physiological function of calpains.	CAPN1 CAPN2 CAPN6	6.07e-06	7	196	3	9396712
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NES SPIRE2 AFTPH KIF1B MAST2 NEDD4 DST SBF1 RAB3GAP2 OSBPL6 DPYSL3 KDM5A ESYT1 PTPN21 ARAF TIMM50 MACF1	8.68e-06	861	196	17	36931259
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	SPIRE2 TPRN PFAS MCCC2 MAST2 KMT2C SBF1 RAB3GAP2 ALOX12B VCP TBC1D15 ACAD10 NCSTN KRR1 NCCRP1	9.60e-06	689	196	15	36543142
Pubmed	CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.	DPYSL2 DPYSL3 CRMP1	9.67e-06	8	196	3	12134159
Pubmed	Altered gene expression for calpain/calpastatin system in motor neuron degeneration (Mnd) mutant mouse brain and spinal cord.	CAPN1 CAPN2 CAPN6	9.67e-06	8	196	3	9473662
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DCAF1 PFAS NCAPG2 SBF1 PTPRH PLS3 VCP DPYSL2 TBC1D15 ESYT1 CAPN2 NUP98 OBSL1 PON2 NCSTN PTPN21 ARAF LTN1	1.14e-05	974	196	18	28675297
Pubmed	CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.	DPYSL2 DPYSL3 CRMP1	1.44e-05	9	196	3	31919978
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	EPHB4 SLK PTDSS1 MCCC2 RETSAT DST MFN2 PLS3 VCP CERS2 P4HA2 DPYSL2 TBC1D15 ESYT1 RPP38 PON2 GEMIN5 CORO1B NCSTN COL18A1 MACF1	1.54e-05	1297	196	21	33545068
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SLK MCCC2 KMT2C RAB3GAP2 PLS3 DPYSL2 DPYSL3 TBC1D15 GEMIN5 CORO1B CREBBP KMT2D BAZ2A	1.60e-05	549	196	13	38280479
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB4 AXL HLA-F PTDSS1 NCAPG2 PLS3 VCP ABCC1 P4HA2 DPYSL2 DPYSL3 ESYT1 PON2 B3GALT6 NCSTN SLC6A6 COL18A1 LTN1 ATM CXADR	1.66e-05	1201	196	20	35696571
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DCAF1 TBKBP1 KIF1B PTDSS1 GOLPH3 BBS9 NCAPG2 OSBPL6 PLS3 ARHGEF6 P4HA2 DYNC2H1 ESYT1 OBSL1 TBC1D25 CORO1B CREBBP ARAF KIFAP3 RP2 PCDH9	2.01e-05	1321	196	21	27173435
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 SLK GON4L PFAS MAST2 NCAPG2 DST SBF1 ANGEL1 OBSL1 FHIP2A ARAF MTIF2 ELP2	2.15e-05	650	196	14	38777146
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SLK PTDSS1 C2CD2L DST RAB3GAP2 CERS2 DPYSL2 TBC1D15 ESYT1 NUP98 CORO1B GBA2 WDR41	2.28e-05	568	196	13	37774976
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	EPS15 SLK KIF1B PFAS RAB3GAP2 PLS3 CAP2 VCP DPYSL2 DPYSL3 TBC1D15 WASHC4 CAPN1 CAPN2 RPP38 NUP98 GEMIN5 CORO1B CRMP1 CNDP2 MACF1 ELP2	2.71e-05	1455	196	22	22863883
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	PFAS TRIM21 CACNA1G ABCC1 DPYSL3 TBC1D15 DYNC2H1 MYO18A CREBBP ARAF CRMP1 TIMM50 ROS1 RIMS2 PCDH9	2.73e-05	754	196	15	35906200
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EPS15 INPP4A MCCC2 DST RAB3GAP2 TBC1D15 KDM5A GEMIN5 ARAF SFMBT2 KMT2D	2.81e-05	418	196	11	34709266
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	AFTPH ATXN2 RAB3GAP2 MCRS1 USH2A DYNC2H1 CAPN1 CAPN2 NUP98 GEMIN5 KRR1 CREBBP MRM3 BORA	3.00e-05	670	196	14	22990118
Pubmed	Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization.	DPYSL2 CRMP1	3.16e-05	2	196	2	22279220
Pubmed	[Expression of calpain 1 and calpain 2 during the skin incised wound healing in mice].	CAPN1 CAPN2	3.16e-05	2	196	2	17619446
Pubmed	SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.	SMG1 ATM	3.16e-05	2	196	2	31565865
Pubmed	Calpain 1 and 2 are required for RNA replication of echovirus 1.	CAPN1 CAPN2	3.16e-05	2	196	2	18032503
Pubmed	Calpain-2 participates in the process of calpain-1 inactivation.	CAPN1 CAPN2	3.16e-05	2	196	2	33078830
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	3.16e-05	2	196	2	11002341
Pubmed	Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle.	CASQ1 CASQ2	3.16e-05	2	196	2	28069951
Pubmed	Cloning of m-calpain 80 kD subunit from the axonal degeneration-resistant WLD(S) mouse mutant.	CAPN1 CAPN2	3.16e-05	2	196	2	9669314
Pubmed	Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.	CASQ1 CASQ2	3.16e-05	2	196	2	24098358
Pubmed	Loss of CRMP1 and CRMP2 results in migration defects of Purkinje cells in the X lobule of the mouse cerebellum.	DPYSL2 CRMP1	3.16e-05	2	196	2	35219721
Pubmed	Vitamin D₃ regulation of body fat, cytokines, and calpain gene expression.	CAPN1 CAPN2	3.16e-05	2	196	2	25520983
Pubmed	hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.	SMG1 ATM	3.16e-05	2	196	2	18332866
Pubmed	Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion.	CAPN1 CAPN2	3.16e-05	2	196	2	15471877
Pubmed	m-Calpain is required for preimplantation embryonic development in mice.	CAPN1 CAPN2	3.16e-05	2	196	2	16433929
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	3.16e-05	2	196	2	31924266
Pubmed	Calpains are required for invasive and metastatic potentials of human HCC cells.	CAPN1 CAPN2	3.16e-05	2	196	2	23733271
Pubmed	Involvement of calpains in growth factor-mediated migration.	CAPN1 CAPN2	3.16e-05	2	196	2	16971167
Pubmed	Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory.	CAPN1 CAPN2	3.16e-05	2	196	2	29258546
Pubmed	Protection against TBI-Induced Neuronal Death with Post-Treatment with a Selective Calpain-2 Inhibitor in Mice.	CAPN1 CAPN2	3.16e-05	2	196	2	28594313
Pubmed	MFN2 Hereditary Motor and Sensory Neuropathy	KIF1B MFN2	3.16e-05	2	196	2	20301684
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	3.16e-05	2	196	2	28967912
Pubmed	Immunhistochemical analysis for expression of calpain 1, calpain 2 and calpastatin in ovarian cancer.	CAPN1 CAPN2	3.16e-05	2	196	2	22335024
Pubmed	ZHX3 promotes the progression of urothelial carcinoma of the bladder via repressing of RGS2 and is a novel substrate of TRIM21.	ZHX3 TRIM21	3.16e-05	2	196	2	33440047
Pubmed	The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia.	KDM5A NUP98	3.16e-05	2	196	2	32381579
Pubmed	Calcium-dependent plasma membrane repair requires m- or mu-calpain, but not calpain-3, the proteasome, or caspases.	CAPN1 CAPN2	3.16e-05	2	196	2	19781581
Pubmed	Calpain-1 and calpain-2 play opposite roles in retinal ganglion cell degeneration induced by retinal ischemia/reperfusion injury.	CAPN1 CAPN2	3.16e-05	2	196	2	27185592
Pubmed	Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation.	CAPN1 CAPN2	3.16e-05	2	196	2	22432027
Pubmed	Cerebral calpain in fatal falciparum malaria.	CAPN1 CAPN2	3.16e-05	2	196	2	17359359
Pubmed	GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding.	GOLPH3 MYO18A	3.16e-05	2	196	2	19837035
Pubmed	Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.	GOLPH3 MYO18A	3.16e-05	2	196	2	23990465
Pubmed	Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons.	DPYSL2 DPYSL3	3.16e-05	2	196	2	22826151
Pubmed	Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects.	CAPN1 CAPN2	3.16e-05	2	196	2	30177812
Pubmed	Calpains: markers of tumor aggressiveness?	CAPN1 CAPN2	3.16e-05	2	196	2	20193680
Pubmed	A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.	CREBBP KMT2D	3.16e-05	2	196	2	27999180
Pubmed	Different expression of calpains in the anterior vaginal wall of women with and without uterovaginal prolapse.	CAPN1 CAPN2	3.16e-05	2	196	2	14980313
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	3.16e-05	2	196	2	36601880
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	3.16e-05	2	196	2	28483418
Pubmed	Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTN.	VCP SPRTN	3.16e-05	2	196	2	35469923
Pubmed	Calsequestrin Deletion Facilitates Hippocampal Synaptic Plasticity and Spatial Learning in Post-Natal Development.	CASQ1 CASQ2	3.16e-05	2	196	2	32751833
Pubmed	CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain.	DPYSL3 CRMP1	3.16e-05	2	196	2	27836492
Pubmed	Axonal morphogenesis controlled by antagonistic roles of two CRMP subtypes in microtubule organization.	DPYSL3 CRMP1	3.16e-05	2	196	2	12814366
Pubmed	Activation of calpains mediates early lung neutrophilic inflammation in ventilator-induced lung injury.	CAPN1 CAPN2	3.16e-05	2	196	2	22140070
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	3.16e-05	2	196	2	34156443
Pubmed	Cloning of the genes encoding mouse cardiac and skeletal calsequestrins: expression pattern during embryogenesis.	CASQ1 CASQ2	3.16e-05	2	196	2	9795116
Pubmed	Differential effect of calsequestrin ablation on structure and function of fast and slow skeletal muscle fibers.	CASQ1 CASQ2	3.16e-05	2	196	2	21941434
Pubmed	Knocking down type 2 but not type 1 calsequestrin reduces calcium sequestration and release in C2C12 skeletal muscle myotubes.	CASQ1 CASQ2	3.16e-05	2	196	2	16595676
Pubmed	Calpain activation contributes to hyperglycaemia-induced apoptosis in cardiomyocytes.	CAPN1 CAPN2	3.16e-05	2	196	2	19505932
Pubmed	Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in type I and type II human skeletal muscle fibres.	CASQ1 CASQ2	3.16e-05	2	196	2	24127619
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	3.16e-05	2	196	2	27280393
Pubmed	Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.	MFN2 KDM5A	3.16e-05	2	196	2	18722178
Pubmed	MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons.	MFN2 CAPN1	3.16e-05	2	196	2	25416777
Pubmed	Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle.	CASQ1 CASQ2	3.16e-05	2	196	2	20713548
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	3.16e-05	2	196	2	36869380
Pubmed	Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human platelets.	INPP4A CAPN1	3.16e-05	2	196	2	9110986
Pubmed	Characterization of the interaction between endostatin short peptide and VEGF receptor 3.	FLT4 COL18A1	3.16e-05	2	196	2	22512651
Pubmed	Differential Activation of Calpain-1 and Calpain-2 following Kainate-Induced Seizure Activity in Rats and Mice.	CAPN1 CAPN2	3.16e-05	2	196	2	27622212
Pubmed	Olfactory bulb core is a rich source of neural progenitor and stem cells in adult rodent and human.	NES DPYSL3	3.16e-05	2	196	2	12687705
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	3.16e-05	2	196	2	25346535
Pubmed	Calpain-mediated cleavage of collapsin response mediator protein(CRMP)-2 during neurite degeneration in mice.	DPYSL2 CAPN1	3.16e-05	2	196	2	18052987
GeneFamily	C2 domain containing\|Calpains	CAPN1 CAPN2 CAPN6	1.52e-04	15	129	3	975
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS13 ADAMTS8	3.16e-04	19	129	3	50
GeneFamily	EF-hand domain containing	EPS15 DST PLS3 CAPN1 CAPN2 MACF1 RASEF	9.97e-04	219	129	7	863
GeneFamily	Fibronectin type III domain containing	EPHB4 AXL PTPRH USH2A ROS1 LRIT1	1.02e-03	160	129	6	555
GeneFamily	WD repeat domain containing\|Coronins	CORO1B CORO6	1.04e-03	7	129	2	495
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	1.38e-03	8	129	2	939
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	AXL FLT4 ROS1	2.89e-03	40	129	3	321
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF597 NES GALNT18 GIMAP6 DPH2 ZWILCH DPYSL3 ALKBH7 CLEC14A	6.81e-08	171	195	9	1ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell	droplet-Fat-Mat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 KIF26A GALNT18 GIMAP6 ADAMTS8 CLEC14A SNAPC2 RIMS2	1.64e-06	185	195	8	d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES KIF26A GALNT18 GIMAP6 FLT4 SLC6A6 CLEC14A	1.84e-06	188	195	8	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES KIF26A GALNT18 GIMAP6 FLT4 SLC6A6 CLEC14A	1.84e-06	188	195	8	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES KIF26A GALNT18 GIMAP6 FLT4 SLC6A6 CLEC14A	1.84e-06	188	195	8	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 GOLPH3 NEDD4 DST PLS3 VCP SLC6A6 COL18A1	2.71e-06	198	195	8	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NES GALNT18 NEDD4 DST FLT4 MINDY2 CRMP1 MACF1	2.92e-06	200	195	8	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF11 C2CD2L ARHGEF6 GEMIN5 LSP1 RP2 RINL	9.46e-06	168	195	7	93b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF11 C2CD2L ARHGEF6 GEMIN5 LSP1 RP2 RINL	9.46e-06	168	195	7	e393553208617a023f1646169c892a87c95db3f5
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	EPS15 SLK C2CD2L NUP98 CREBBP TIMM50 WDR41	1.23e-05	175	195	7	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AFTPH TRIM21 MCCC2 B3GALT6 FHIP2A CNDP2 RP2	1.65e-05	183	195	7	3cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EPHB4 LDLRAP1 FLT4 FOXN4 COL18A1 CLEC14A ARHGAP28	1.83e-05	186	195	7	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	facs-Skin-Anagen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GOLPH3 PLS3 VCP CAPN1 CAPN2 SLC6A6 COL18A1	2.10e-05	190	195	7	888ded899f0513d41bf655896d59ae8ef74e0978
ToppCell	EC\|World / Lineage and Cell class	EPHB4 KIF26A GALNT18 PLS3 GIMAP6 FLT4 CLEC14A	2.24e-05	192	195	7	478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 PTGIS NEDD4 DST PRPF40B DPYSL3 CLEC14A	2.24e-05	192	195	7	452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 PTGIS NEDD4 DST PRPF40B DPYSL3 CLEC14A	2.24e-05	192	195	7	7ddaca206599603d4d0b2afb73ed2850225d277d
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 PTGIS NEDD4 DST PRPF40B DPYSL3 CLEC14A	2.24e-05	192	195	7	bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 GALNT18 DST PLS3 CAP2 ADAMTS8 CLEC14A	2.32e-05	193	195	7	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 GALNT18 DST PLS3 CAP2 ADAMTS8 CLEC14A	2.32e-05	193	195	7	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	facs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS19 GALNT18 PLS3 CAPN2 SLC6A6 COL18A1 MACF1	2.32e-05	193	195	7	eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS19 GALNT18 PLS3 CAPN2 SLC6A6 COL18A1 MACF1	2.40e-05	194	195	7	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 GALNT18 DST PLS3 CAP2 ADAMTS8 CLEC14A	2.40e-05	194	195	7	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES TBKBP1 GALNT18 GIMAP6 FLT4 CLEC14A	2.48e-05	195	195	7	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEDD4 DST PLS3 CAPN2 SLC6A6 COL18A1 MACF1	2.56e-05	196	195	7	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PTGIS GALNT18 MAMDC2 CAP2 DPYSL3 CAPN2 SLC6A6	2.56e-05	196	195	7	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEDD4 DST PLS3 CAPN2 SLC6A6 COL18A1 MACF1	2.56e-05	196	195	7	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	Endothelial_cells\|World / lung cells shred on cell class, cell subclass, sample id	NES PTGIS GIMAP6 DPYSL3 FLT4 COL18A1 CLEC14A	2.73e-05	198	195	7	b93effa428ec036542fa21647dfef9589c64640f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	NEXMIF ANKS1B CAP2 CASQ1 CASQ2 CORO6	2.90e-05	135	195	6	451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NES GALNT18 PLS3 GIMAP6 FLT4 PON2 CLEC14A	2.91e-05	200	195	7	3767abc75176779198505ebc6967d55ce322d9fe
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NES GALNT18 PLS3 GIMAP6 FLT4 PON2 CLEC14A	2.91e-05	200	195	7	e0a003d2a5fd6adfcb817c9bc5dceb9c79e7491b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPHB4 NES GALNT18 NEDD4 FLT4 MINDY2 CRMP1	2.91e-05	200	195	7	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm\|6m / Sample Type, Dataset, Time_group, and Cell type.	NES CHRND MAMDC2 CAP2 KLHL40 CASQ2 CORO6	2.91e-05	200	195	7	0f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANKS1B PKHD1 USH2A SFMBT2 ROS1 RIMS2	8.01e-05	162	195	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GALNT18 GIMAP6 FLT4 CRMP1 COL18A1 CLCA2	8.29e-05	163	195	6	c21114826bee1b05b411984326fef6b6e0d05316
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GALNT18 GIMAP6 FLT4 CRMP1 COL18A1 CLCA2	8.29e-05	163	195	6	5d49414432db259a19df50d7944581d00b69f537
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHRND CRMP1 CFAP74 LSP1 SYTL1 RINL	9.47e-05	167	195	6	5d1919bea8e5a52ac6fc953caff15509b7142923
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHRND CRMP1 CFAP74 LSP1 SYTL1 RINL	9.47e-05	167	195	6	d8f497860d48342a3aaaad328f88e4d55ab4faeb
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTC16 MAST2 MFN2 ZNF649 B3GALT6 FAM72A	9.79e-05	168	195	6	94cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|World / disease group, cell group and cell class (v2)	TBKBP1 ABCC1 ESYT1 ANGEL1 RPP38 PCDH9	1.01e-04	169	195	6	2bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TBKBP1 ABCC1 ESYT1 ANGEL1 RPP38 PCDH9	1.08e-04	171	195	6	78491478ba65bad45238fe114f5251b2adea323d
ToppCell	E12.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GIMAP6 FLT4 PON2 CRMP1 COL18A1 CLEC14A	1.11e-04	172	195	6	ba99688e9f46671deccf824b1e77c6db0742d7df
ToppCell	E12.5-Endothelial-proliferative_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GIMAP6 FLT4 PON2 CRMP1 COL18A1 CLEC14A	1.11e-04	172	195	6	2136170f6e1204734cec7dbf7b32e7d5179b92b5
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	AXL NEXMIF LIAT1 FLT4 COL18A1 CXADR	1.11e-04	172	195	6	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAST2 NEDD4 MAMDC2 P4HA2 DYNC2H1 NUP98	1.15e-04	173	195	6	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	TCGA-Brain-Primary_Tumor\|TCGA-Brain / Sample_Type by Project: Shred V9	ZHX3 MCCC2 BBOX1 ARHGEF6 PON2 CASQ1	1.15e-04	173	195	6	f6ba22661e67c17d49d1058d4170ba8f36bf47f0
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	EPHB4 KIF26A GALNT18 GIMAP6 FLT4 CLEC14A	1.19e-04	174	195	6	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	10x3'2.3-week_17-19-Myeloid_DC-DC-DC2\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NACA2 AXL DPYSL2 CAPN2 CNDP2 LSP1	1.19e-04	174	195	6	60ee7c6f1b6972e6647a16848087cc60e0060bbe
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 KIF26A B3GALT6 KIFAP3 CLEC14A FAM72A	1.22e-04	175	195	6	98dc3b6f69a29d587f503898f09912700950e3d9
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZHX3 EPS15 NACA2 P4HA2 FHIP2A CORO6	1.22e-04	175	195	6	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	AT1_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	DST PLS3 DPYSL2 CAPN2 PTPN21 CXADR	1.30e-04	177	195	6	3128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZHX3 KIF26A TPRN TMEM132E CLEC14A GDPGP1	1.38e-04	179	195	6	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEXMIF ANKS1B CASQ2 ADAMTS8 SFMBT2 TBC1D23	1.38e-04	179	195	6	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	KIF26A INPP4A NEXMIF PTGIS TDRKH KIFAP3	1.38e-04	179	195	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DST CAP2 ADAMTS8 TEX11 PCSK7 MACF1	1.47e-04	181	195	6	beb2771820956be8b190c0088ae3c4efdb53c897
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NES GALNT18 FLT4 PON2 CLEC14A ARHGAP28	1.52e-04	182	195	6	997d37ca2af661c92a56add888762724dfccc890
ToppCell	normal_Lung-Endothelial_cells-Tumor_ECs\|normal_Lung / Location, Cell class and cell subclass	NES PLS3 DPYSL3 FLT4 COL18A1 CLEC14A	1.61e-04	184	195	6	7ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCell	droplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAMDC2 CACNA1G CAP2 CASQ2 ADAMTS8 RIMS2	1.61e-04	184	195	6	f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCell	droplet-Heart-nan-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES BBS9 GIMAP6 SLC6A6 CLEC14A	1.66e-04	185	195	6	11a44006950f6ccade86a85d5f06696d2036ffde
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	NES GALNT18 NEDD4 PLS3 PON2 CLEC14A	1.66e-04	185	195	6	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NES KIF26A PROZ CRMP1 COL18A1 CLEC14A	1.70e-04	186	195	6	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	NES KIF26A PROZ CRMP1 COL18A1 CLEC14A	1.70e-04	186	195	6	c3449e54454009973818fc1101933c6f0168258c
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ADAMTS19 AXL ANKS1B PTGIS MAMDC2 LSP1	1.76e-04	187	195	6	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	E12.5-Endothelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GIMAP6 FLT4 PON2 CRMP1 COL18A1 CLEC14A	1.76e-04	187	195	6	b8ed57b3c39ffbf750cd08a3e03ec11dae43d00e
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DST MAMDC2 DPYSL3 ADAMTS8 MACF1 ARHGAP28	1.76e-04	187	195	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	NES GALNT18 NEDD4 PLS3 PON2 CLEC14A	1.76e-04	187	195	6	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	Endothelial-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	ASIC2 KIF26A FLT4 NUP98 PTPN21 ZNF333	1.81e-04	188	195	6	ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NEDD4 DST PLS3 DPYSL3 OBSL1 PCDH9	1.86e-04	189	195	6	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	EC-Sinusoidal_ECs\|World / Lineage and Cell class	EPHB4 GALNT18 GIMAP6 FLT4 CLEC14A CXADR	1.86e-04	189	195	6	9a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	SMG1 HLA-F NEDD4 LENG8 PCSK7 ATM	1.86e-04	189	195	6	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NES KIF26A PTGIS DPYSL3 NLRP1 CLEC14A	1.86e-04	189	195	6	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	facs-Skin-Anagen\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLS3 VCP CAPN1 NCSTN SLC6A6 COL18A1	1.86e-04	189	195	6	adbfc723130079b4caf551f66d2aee86fab1903c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	ANKS1B GALNT18 DST PLS3 CAPN2 PTPN21	1.86e-04	189	195	6	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	AXL DST PLS3 ABCC1 DPYSL3 CLCA2	1.91e-04	190	195	6	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KIF1B BCAT2 PTGIS TDRKH DPYSL3 RINL	1.91e-04	190	195	6	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	droplet-Marrow-nan-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 ESYT1 CAPN2 CORO1B TEP1 CNDP2	1.91e-04	190	195	6	95d8dc8488e95158e84a44bb53ea4ab7bf3d44bb
ToppCell	facs-Skin-Anagen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GOLPH3 PLS3 VCP CAPN1 CAPN2 COL18A1	1.91e-04	190	195	6	3466cebab16964e94da130d0673fa32e7d90b5ed
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL NEDD4 CAP2 OBSL1 CASQ2 PCDH9	1.91e-04	190	195	6	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	OVOL2 CLEC14A PCSK7 MACF1 ATM	1.92e-04	121	195	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL PTGIS MAMDC2 CAP2 CASQ2 ADAMTS8	1.97e-04	191	195	6	8597a8af294f24496c317d995f07eb5dcc25c13c
ToppCell	(7)_Epithelial-E_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	BCAT2 GUCY2D RASEF ROS1 PCDH9 CXADR	1.97e-04	191	195	6	0fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB4 SLK KIF26A DST SLC6A6 CLEC14A	1.97e-04	191	195	6	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST MAMDC2 DPYSL3 ADAMTS8 MACF1 ARHGAP28	1.97e-04	191	195	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 KIF26A GIMAP6 DPYSL3 FLT4 CLEC14A	2.02e-04	192	195	6	f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NES GALNT18 GIMAP6 SLC6A6 CLEC14A	2.02e-04	192	195	6	24d28e28a5c54ca7770f7e5ad7f4d00039e0aaf9
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL PTGIS PLS3 CAP2 COL18A1 CLCA2	2.02e-04	192	195	6	26d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST MAMDC2 DPYSL3 ADAMTS8 MACF1 ARHGAP28	2.02e-04	192	195	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 KIF26A GIMAP6 DPYSL3 FLT4 CLEC14A	2.02e-04	192	195	6	bcd8876235be503186f119653b39476488c0fa15
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 GALNT18 GIMAP6 DPYSL3 FLT4 CLEC14A	2.02e-04	192	195	6	5890076929598e88fe9d59a4e4e858b446746ce9
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	BCAT2 DST PLS3 CAPN6 PTPN21 COL18A1	2.02e-04	192	195	6	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES SLK GIMAP6 DPYSL3 FLT4 CLEC14A	2.02e-04	192	195	6	3c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL PTGIS PLS3 CAP2 COL18A1 CLCA2	2.08e-04	193	195	6	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 INPP4A TEX11 PCSK7 MACF1 ATM	2.08e-04	193	195	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL PTGIS PLS3 CAP2 COL18A1 CLCA2	2.08e-04	193	195	6	7fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST MAMDC2 ADAMTS8 MACF1 CORO6 ARHGAP28	2.08e-04	193	195	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST MAMDC2 ADAMTS8 MACF1 CORO6 ARHGAP28	2.08e-04	193	195	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	AXL DST CACNA1G CAPN2 PON2 CNDP2	2.08e-04	193	195	6	984ea5b871479527ab57dd813bacae844c0d8c06
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	ADAMTS19 AXL ANKS1B PTGIS MAMDC2 DYNC2H1	2.08e-04	193	195	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	AXL DST CACNA1G CAPN2 PON2 CNDP2	2.08e-04	193	195	6	529281b912070c8655e38880ac73f5e4bd6ee4ce
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NES HLA-F GALNT18 PLS3 PON2 CLEC14A	2.08e-04	193	195	6	aaf681f16f310168e4719464814a1fc0a2f8431a
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NES KIF26A GALNT18 DPYSL3 COL18A1 CLEC14A	2.14e-04	194	195	6	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	4.08e-05	2	189	2	DOID:0080598 (implicated_via_orthology)
Disease	choroidal sclerosis (is_implicated_in)	PRPH2 GUCY2D	4.08e-05	2	189	2	DOID:980 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease, type 2A	KIF1B MFN2	4.08e-05	2	189	2	cv:C2079538
Disease	brain measurement, neuroimaging measurement	VWA5B2 ADAMTS19 ZHX3 BBS9 P4HA2 DPYSL2 DPYSL3 ADAMTS8 GBA2 CRMP1 COL18A1 MACF1 CORO6	5.97e-05	550	189	13	EFO_0004346, EFO_0004464
Disease	Ciliopathies	BBS9 PKHD1 CPLANE1 USH2A DYNC2H1 GUCY2D	7.87e-05	110	189	6	C4277690
Disease	Central areolar choroidal sclerosis	PRPH2 GUCY2D	1.22e-04	3	189	2	C1536451
Disease	tetradecenoylcarnitine meaasurement	ALOX12B ABCC1	1.22e-04	3	189	2	EFO_0021809
Disease	retinitis pigmentosa (is_implicated_in)	USH2A PRPH2 GUCY2D RP2	1.37e-04	41	189	4	DOID:10584 (is_implicated_in)
Disease	Intellectual Disability	INPP4A GON4L KMT2C CACNA1G PJA1 KDM5A FHIP2A COL18A1 MACF1 ELP2 TBC1D23	1.57e-04	447	189	11	C3714756
Disease	Gastric Adenocarcinoma	EPHB4 AXL ROS1 ATM	1.98e-04	45	189	4	C0278701
Disease	Profound Mental Retardation	INPP4A GON4L CACNA1G KDM5A COL18A1 ELP2	2.83e-04	139	189	6	C0020796
Disease	Mental Retardation, Psychosocial	INPP4A GON4L CACNA1G KDM5A COL18A1 ELP2	2.83e-04	139	189	6	C0025363
Disease	Mental deficiency	INPP4A GON4L CACNA1G KDM5A COL18A1 ELP2	2.83e-04	139	189	6	C0917816
Disease	Adenocarcinoma of lung (disorder)	SLK ALOX12B XPC CREBBP ARAF ROS1 ATM	3.82e-04	206	189	7	C0152013
Disease	hereditary spastic paraplegia 76 (implicated_via_orthology)	CAPN1 CAPN2	4.03e-04	5	189	2	DOID:0110821 (implicated_via_orthology)
Disease	splicing factor 3B subunit 4 measurement	MTMR11 MFN2	4.03e-04	5	189	2	EFO_0803100
Disease	Disorder of eye	BBS9 MFN2 CPLANE1 USH2A PRPH2 GUCY2D RP2	4.54e-04	212	189	7	C0015397
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	BCAT2 ATXN2 CERS2 PCSK7 MACF1	5.39e-04	103	189	5	EFO_0008595, EFO_0020944
Disease	Sezary Syndrome	KMT2C CREBBP KMT2D	6.75e-04	27	189	3	C0036920
Disease	Drug-Induced Stevens Johnson Syndrome	PTGIS NEDD4 VCP	8.36e-04	29	189	3	C1274933
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	PTGIS NEDD4 VCP	8.36e-04	29	189	3	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	PTGIS NEDD4 VCP	8.36e-04	29	189	3	C3658302
Disease	Toxic Epidermal Necrolysis	PTGIS NEDD4 VCP	8.36e-04	29	189	3	C0014518
Disease	Stevens-Johnson Syndrome	PTGIS NEDD4 VCP	9.24e-04	30	189	3	C0038325
Disease	clopidogrel metabolite measurement	ASIC2 MYO18A TMEM132E	1.22e-03	33	189	3	EFO_0007966
Disease	carbohydrate intake measurement	ATXN2 PJA1 ACAD10	1.34e-03	34	189	3	EFO_0010811
Disease	neuroimaging measurement	VWA5B2 ZHX3 SPIRE2 KIF1B ARHGEF11 BBS9 ATXN2 RAB3GAP2 PKHD1 DPYSL2 DPYSL3 CAPN2 PTPN21 CRMP1 COL18A1 MACF1	1.50e-03	1069	189	16	EFO_0004346
Disease	creatinine measurement	NACA2 SPIRE2 INPP4A GOLPH3 MAST2 C2CD2L PKHD1 CERS2 P4HA2 ACAD10 SLC34A3 TEX11 FAM135B CRMP1 COL18A1	1.96e-03	995	189	15	EFO_0004518
Disease	coagulation factor XA measurement	PROZ ABCC1	2.16e-03	11	189	2	EFO_0020266
Disease	Nodular glomerulosclerosis	AXL MFN2 CNDP2	2.31e-03	41	189	3	C0017667
Disease	age-related macular degeneration, disease progression measurement	BBS9 FAM135B PCDH9	2.31e-03	41	189	3	EFO_0001365, EFO_0008336
Disease	Charcot-Marie-Tooth disease	KIF1B SBF1 MFN2	2.47e-03	42	189	3	cv:C0007959
Disease	acute myeloid leukemia (implicated_via_orthology)	NUP98 CREBBP	2.58e-03	12	189	2	DOID:9119 (implicated_via_orthology)
Disease	Diabetic Nephropathy	AXL MFN2 CNDP2	2.82e-03	44	189	3	C0011881
Disease	autism spectrum disorder (implicated_via_orthology)	NEXMIF KDM5A CREBBP ELP2 RIMS2	3.03e-03	152	189	5	DOID:0060041 (implicated_via_orthology)
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	NACA2 PKHD1	3.04e-03	13	189	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	ventricular enlargement measurement	GALNT18 ABCC1	3.04e-03	13	189	2	EFO_0010570
Disease	coagulation factor X measurement	PROZ ABCC1	3.04e-03	13	189	2	EFO_0020265
Disease	phosphatidylcholine 36:5 measurement	ADAMTS19 RASEF	3.53e-03	14	189	2	EFO_0010383
Disease	Malignant neoplasm of breast	EPHB4 ADAMTS19 CHRND NEDD4 PLS3 ABCC1 DYNC2H1 NUP98 ARAF KMT2D CLCA2 MACF1 LSP1 ZFYVE26 ATM	4.00e-03	1074	189	15	C0006142
Disease	Lymphoma, Follicular, Grade 2	CREBBP KMT2D	4.06e-03	15	189	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	CREBBP KMT2D	4.06e-03	15	189	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	CREBBP KMT2D	4.06e-03	15	189	2	C1956130
Disease	myelodysplastic syndrome (implicated_via_orthology)	ASXL1 CREBBP	4.06e-03	15	189	2	DOID:0050908 (implicated_via_orthology)
Disease	Lymphoma, Large-Cell, Follicular	CREBBP KMT2D	4.06e-03	15	189	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	CREBBP KMT2D	4.06e-03	15	189	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	CREBBP KMT2D	4.06e-03	15	189	2	C0079758
Disease	cholesteryl esters to total lipids in IDL percentage	CERS2 PCSK7 MACF1	4.06e-03	50	189	3	EFO_0022247
Disease	phospholipids in IDL measurement	TBKBP1 BCAT2 ATXN2	4.54e-03	52	189	3	EFO_0022164
Disease	Pheochromocytoma, Extra-Adrenal	KIF1B DBH	4.62e-03	16	189	2	C1257877
Disease	Metastatic melanoma	EPHB4 FLT4 GUCY2D	5.05e-03	54	189	3	C0278883
Disease	Charcot-Marie-Tooth disease type 2	KIF1B MFN2	5.21e-03	17	189	2	cv:C0270914
Disease	blood phosphate measurement	ZHX3 EPS15 TBKBP1 ATXN2 SLC34A3	5.37e-03	174	189	5	EFO_0010972
Disease	melanoma	CAPN1 RPP38 XPC FHIP2A ROS1 ATM	5.41e-03	248	189	6	C0025202
Disease	cortical thickness	VWA5B2 ZHX3 SPIRE2 ASIC2 MAST2 BBS9 ATXN2 PKHD1 P4HA2 DPYSL2 ADAMTS8 MINDY2 CRMP1 COL18A1 MACF1	5.53e-03	1113	189	15	EFO_0004840
Disease	Hypercholesterolemia, Familial	LDLRAP1 PON2	5.84e-03	18	189	2	C0020445
Disease	Amyotrophic Lateral Sclerosis	ATXN2 VCP PON2	6.16e-03	58	189	3	C0002736
Disease	immature platelet fraction	LDLRAP1 KIF1B P4HA2 BAZ2A	6.29e-03	114	189	4	EFO_0009187

Protein segments in the cluster

Peptide	Gene	Start	Entry
ADWEDVVLLPASQPE	ERI2	406	A8K979
SRVIDEELNPQWGET	ESYT1	371	Q9BSJ8
EWIIIDPEGFTENGE	CHRND	196	Q07001
EDVSLGAWLAPVDVQ	B3GALT6	241	Q96L58
TVAEGQEPAEFWDLL	AVIL	581	O75366
ILSEPIQAWEGEDIK	ARHGEF6	431	Q15052
ALPESGELLDVWTEL	AFTPH	691	Q6ULP2
LIVEDEKWGPEVSDN	ADAMTS8	271	Q9UP79
DTPEGLQWVQLSAEE	BAZ2A	626	Q9UIF9
ISVGSDSDLVIWDPD	DPYSL3	401	Q14195
GIWESPELDRNLAED	ARHGEF11	1296	O15085
EGDFWPNVLEESIKE	CREBBP	1541	Q92793
AEEWVSGRDADPILI	CORO1B	376	Q9BR76
ESELWETPDVSLITG	DPH2	401	Q9BQC3
PEVLAVLDWELSTLG	ACAD10	476	Q6JQN1
VLDWELSTLGDPLAD	ACAD10	481	Q6JQN1
FGEWVDVVVDDLLPI	CAPN1	156	P07384
LPVNLTWADLEDRDG	CERS2	16	Q96G23
STQWEVAPEKGEELE	ATG2A	746	Q2TAZ0
AEEGLDPLDSLTSLW	ASXL1	946	Q8IXJ9
EEIRIWGPLQEDADI	ADAMTS13	641	Q76LX8
LDIQQDEYLPIWGET	ASIC2	221	Q16515
LEDVASVLDWKPQGS	RASEF	491	Q8IZ41
EAESSEDEAGPWILL	RILP	311	Q96NA2
GIVSELQFAPDREEW	ADAMTS19	21	Q8TE59
PAEITLTWQRDGEEQ	HLA-F	231	P30511
VLEEGDTDPWTLPQL	SLC34A3	36	Q8N130
ELEELGELSPCWESL	INPP4A	276	Q96PE3
WSIPSRLDEKVEEEG	KCNJ9	351	Q92806
VEKEEDLQWVLTDGP	NCSTN	76	Q92542
IESSESELPEIGWLQ	KCNH3	386	Q9ULD8
DSVLASLPWILNEEG	MAMDC2	36	Q7Z304
EKIEGWELTTEPSLT	LTN1	561	O94822
LPENWTDTRETLLEG	LDLRAP1	31	Q5SW96
PTSVAEWLDSIELGD	ANKS1B	886	Q7Z6G8
WTKDGEEVVESPALL	OBSL1	931	O75147
DTEDAWLSVEGPISI	RAB3GAP2	1126	Q9H2M9
LELELEVVWGPDSHL	MUC6	146	Q6W4X9
NPTDDLVLNDGVLWD	DCAF1	1231	Q9Y4B6
DWVKEASGDLPEAQI	NUP98	1251	P52948
GWSEQLPDTLVDESV	KMT2C	1321	Q8NEZ4
EDLVLSDISPKGVWD	KMT2C	4621	Q8NEZ4
AEQAEELEPGWVVLD	NEDD4	581	P46934
VWDDGIIDPADTRLV	MCCC2	526	Q9HCC0
PQVDGQWEELSGLDE	EPHB4	36	P54760
AEGVDVWSLEPEDLS	GK3P	466	Q14409
WRDLPSAGEEILEVE	MTIF2	421	P46199
AELLAEEAGIALVPW	GUCY2D	136	Q02846
AISSESLADQEWGLP	MTMR11	596	A4FU01
IAVGSDADLVIWDPD	DPYSL2	401	Q16555
QLDRTEWGSDLPSVE	DST	621	Q03001
DLLVWFEISELEPTG	KIF1B	1251	O60333
LEPWDAGELTANEEL	ATXN2	371	Q99700
LESSGADPDWQELQI	LENG8	536	Q96PV6
LWEELLDDEQPAITV	NCCRP1	166	Q6ZVX7
TAWDGSKLITEPAEI	CAP2	461	P40123
DLLAPDLLEQGDWSL	PCSK7	746	Q16549
TKPENQDIDWTLLEG	PLS3	381	P13797
LPAELEEQSIGRFDW	PCDH9	906	Q9HC56
WLLEEEALVPGASED	MYO18A	881	Q92614
DETLVWEALVKPGDL	NLRP1	1341	Q9C000
VPEGWLIFVAEQEEL	COL18A1	1461	P39060
EQGELNATEEVWIPG	NES	996	P48681
EPLLSWLADTEELIA	MACF1	1481	O94854
GALIDTVDWTREAPD	LCA10	131	Q71F78
ENQDESELLTVPDGW	KRR1	26	Q13601
GDQREDSSAWPELLV	KIF26A	921	Q9ULI4
EDILVVINVSPLEWG	GDPGP1	151	Q6ZNW5
ESGELVPTELNDIWR	KLHL40	571	Q2TBA0
NVLLWGNLPEIEEST	FAM72A	121	Q5TYM5
SLGVSVRSWDELPDE	OVOL2	11	Q9BRP0
VPLSKEADSWEIIEG	OSBPL6	61	Q9BZF3
ILPEEEEYALSGWNL	KDM5A	431	P29375
FLPLQEDTQELGWEE	BBS9	756	Q3SYG4
LDGWAPNLAFIETEL	LRIT1	216	Q9P2V4
AEWGNDLPSVELQLE	MACF1	606	Q9UPN3
PGIDVTTELDSWIDK	MFN2	201	O95140
LETELGQPAERWKDT	SBF1	1661	O95248
TLEEGLPLAVQEWEH	NUTM1	256	Q86Y26
PVGWLQDEKVLEEAT	PTPN21	171	Q16825
DWPALEDLVLQDSAA	P4HA2	96	O15460
GHSLEEDLEWSEPQI	RIMS2	606	Q9UQ26
EDLEWSEPQIKDSGV	RIMS2	611	Q9UQ26
LVDNLSIDPSSGDIW	PON2	266	Q15165
VVSWRLEPEDGTALD	BAGE3	26	Q86Y29
GDIDPEWIESLNSVL	DYNC2H1	2056	Q8NCM8
FEGLDDINLWIPLSE	ATM	1786	Q13315
VRSLGWVEVPEEDLA	APBB3	121	O95704
VTAWDTAIAPLDGEE	ARAF	71	P10398
EVEWTEDLALDLGPQ	C2CD2L	331	O14523
ELDTELSWISGDLLP	CACNA1G	2216	O43497
IGSFEVNIWEPIEEE	CPLANE1	1426	Q9H799
GTVWLEVLEDSLPEE	GBA2	491	Q9HCG7
SPEDQGPLDIEWLIS	CXADR	46	P78310
IADETTWIKEPVDNG	BORA	441	Q6PGQ7
TENPDLSIIWIDPDD	CASQ1	311	P31415
IPLDPEGSLELSWNV	DBH	51	P09172
WNIPQEDSGIDIGDI	GALNT18	421	Q6P9A2
LVWDASETEKLPGTV	GON4L	2031	Q3T8J9
WGSELQLPTLDFEDV	BBOX1	116	O75936
PETVQNWIELLSGET	GOLPH3	146	Q9H4A6
DEWLSGQDAEPVLIS	CORO6	376	Q6QEF8
AVEGDPELQSWVQEI	ALOX12B	526	O75342
DNQIDVDLSLEGPAW	MCRS1	371	Q96EZ8
EELFGQVISDEIVWP	MAST2	731	Q6P0Q8
EEREELLGPTAQWSV	LSP1	11	P33241
LLGPTAQWSVEDEEE	LSP1	16	P33241
TDNPDLSILWIDPDD	CASQ2	296	O14958
PVDILGRVWELSDID	EPS15	161	P42566
VQDLVWDPEGEFIIT	ELP2	391	Q6IA86
LDIDGDWNTLPVIFE	FAM135B	396	Q49AJ0
PLDIETVEAINWGLD	FHIP2A	326	Q5W0V3
VVSWRLEPEDGTALD	BAGE2	26	Q86Y30
LIEVDKDWVPDAAGT	BCAT2	151	O15382
PENTGTIELDLISWL	CAPN2	681	P17655
WTEVVIDDLLPTING	CAPN6	131	Q9Y6Q1
EEETLAEPEISGLWN	CFAP74	446	Q9C0B2
IAVGSDADVVIWDPD	CRMP1	401	Q14194
AAALSPEDETWEVLE	IRGQ	411	Q8WZA9
GTLANLTIPDLDWEL	KIFAP3	526	Q92845
EIETVRFLLEWGADP	RFXANK	136	O14593
VSDFLLLGLSEWPEE	OR1N2	26	Q8NGR9
LSLWTDDPIVNGTQE	ABCC1	996	P33527
DDDLPGDLQSLSWLT	FOXN4	36	Q96NZ1
INWEQIPEGISDLEL	MINDY2	531	Q8NBR6
LDQITEGQLDWAPLS	RETSAT	136	Q6NUM9
NIFLGEVEVPLDTWD	SYTL1	361	Q8IYJ3
EETNLWVLIDGLVPF	USH2A	2391	O75445
DITRLEDPQVWIDAG	SLC6A6	281	P31641
RDLNPEDFWEIIGEL	SLK	26	Q9H2G2
PWLQDRIEDSGENLE	RPP38	206	P78345
PSEDSPLLEDWDIIS	TBC1D25	126	Q3MII6
WDIISPKDVIGSDVL	TBC1D25	136	Q3MII6
LGPDWLVEVTDLVSD	TMEM132E	616	Q6IEE7
DVPGEESWLEGLSQI	GIMAP6	261	Q6P9H5
INESLRWDGILADPE	LIAT1	166	Q6ZQX7
EDIKDWSDLVTPQGI	MRM3	171	Q9HC36
GELESILWQAEQPVS	PTGIS	311	Q16647
VPDVSIIWGEEDKNL	NEXMIF	366	Q5QGS0
PWLSELDESATEGVI	SMG1	1716	Q96Q15
DLQSLEPINVWSGEA	SPATA31E1	851	Q6ZUB1
DAGENDLSLLELEWP	PROZ	256	P22891
VLALEDAVDWNPGDE	PKHD1	2061	P08F94
DAVDWNPGDEVVIIS	PKHD1	2066	P08F94
QESVLGKPELWSQDE	STRC	1371	Q7RTU9
VHTQEPGEWLELLLE	ALKBH7	146	Q9BT30
VGALATEQWEEDPAV	ANGEL1	166	Q9UNK9
GGLESDTLQWVEEPQ	CLEC14A	121	Q86T13
KVEEELTLSWTAPGE	CLCA2	776	Q9UQC9
NLLTDVLLESPVDGW	NCAPG2	56	Q86XI2
ALEDGWDSEPFTLVE	CNDP2	106	Q96KP4
GADAFLPALTEELIW	RINL	451	Q6ZS11
EELIWSPDIGDTQLD	RINL	461	Q6ZS11
PWDGNSDDRVLLDLS	TIMM50	266	Q3ZCQ8
TGVTEWLEPLEAKSA	ZWILCH	281	Q9H900
LARIAPSGDQWEEEA	TDRKH	421	Q9Y2W6
LQEDLGVLTSLDWAP	TEP1	2366	Q99973
VPQVTWEDIGGLEDV	VCP	471	P55072
WDPVDAETVVGLARD	UBA7	311	P41226
SESEGWLLEKSVPET	PRPH2	301	P23942
SGRAWVSPEELEEIQ	SPDYE21	371	A0A494C086
SGRAWVSPEELEEIQ	SPDYE5	371	A6NIY4
WGLDESEERELSPQL	SPIRE2	111	Q8WWL2
PVDEGELEAEWLQDV	ARHGAP28	106	Q9P2N2
ESWLLPGSNDLLLEV	PFAS	76	O15067
EEPVGELRALWEETS	PFAS	1001	O15067
SLASWDGILDLPEQN	TBC1D23	66	Q9NUY8
SPDQEAEDLWLSPLT	FLT4	996	P35916
DGTAQVWDALREEPL	GEMIN5	661	Q8TEQ6
EEERLVLESNPLEWT	SFMBT2	811	Q5VUG0
SGELNWSLLPEDAVV	RP2	181	O75695
VPLGEDEQDDWIVVS	AXL	86	P30530
LNDPLLESFLESVWE	TEX11	751	Q8IYF3
VPALELGTAWEEVRE	PRPF40B	641	Q6NWY9
ISDIIELFELGPSAW	ROS1	591	P08922
ENIILVGDDFWIPET	ROS1	1846	P08922
IPEEEAEWVGLTLEE	MRPL28	196	Q13084
PVSLEEWTKNIDSEG	TBC1D15	316	Q8TC07
LDPDTANPWLILSED	TRIM21	291	P19474
LVDASWELVDPTPDL	SPRTN	31	Q9H040
ATGVAWESQLKPEEL	ZNF333	71	Q96JL9
RPIWTAEDQLDGSLE	TJP3	766	O95049
SLQEEGLAWEELAAP	VWA5B2	186	Q8N398
LGKSPLEVEAQWAVE	TPRN	381	Q4KMQ1
DSIGDVWDFNLDPIA	WASHC4	51	Q2M389
SWKQGEPLIATSEEL	TTC16	541	Q8NEE8
LIFTLEQGEDPWLLE	ZNF782	56	Q6ZMW2
LGTNTLSEILDSPWE	ZNF597	136	Q96LX8
LSEILDSPWEGAKNV	ZNF597	141	Q96LX8
NDWEEVEELSEPVLG	XPC	131	Q01831
VWFGENLDPAILEEV	SIRT5	221	Q9NXA8
RLKQGISWSPEEIED	ZHX3	356	Q9H4I2
ILTQEALGPSEVWLD	TBKBP1	11	A7MCY6
EEQASLEEGEIPWLQ	PJA1	451	Q8NG27
ISLSWEVPDGLDSQN	PTPRH	46	Q9HD43
ENLLESIDPTLESWG	ZFYVE26	2221	Q68DK2
DDSVPEDNIWRGILS	PTDSS1	61	P48651
EVWTDLAEKITGPLE	SNAPC2	101	Q13487
EVTASLGWDLDSLDP	SNRNP48	31	Q6IEG0
VAPTEGSLEWDILEV	WDR41	201	Q9HAD4
EEPWVLDLQGAEGTE	ZNF7	61	P17097
ISQLERGDEPWVLDV	ZNF34	86	Q8IZ26
ISLLEQGEEPWSVEQ	ZNF606	111	Q8WXB4
GLLVWQQEEPSEFDL	XKR8	106	Q9H6D3
EQGEPLWTLEDEIHS	ZNF649	61	Q9BS31
WEKDEELGQLSTISP	KMT2D	2006	O14686
AWLVAAAEIDEEPVG	NACA2	51	Q9H009
NGLIPWTLDNTISEE	MYSM1	46	Q5VVJ2
IWALSEVLETGQTPE	NEUROD4	136	Q9HD90