Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

RELN COMP DSPP LAMA5 SPOCK2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 MUC2

1.17e-0818817513GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

FAT4 COMP DSPP CRTAC1 SPOCK2 CHORDC1 PPEF2 ADGRE2 CBLB SLIT2 EDEM3 FBLN1 THBS3 THBS4 FBN1 DST HMCN2 HMCN1 NRXN1 NCAN SLIT1 LRP4 PLCB3 CALN1

4.17e-0874917524GO:0005509
GeneOntologyBiologicalProcessregulation of synapse organization

RELN KIF1A MYO5B KALRN USP9X PPP1R9A CRTAC1 ADGRE2 ADNP SLIT2 PTPN13 NRXN1 NCAN SLIT1 NGEF LRP4 ELAVL2

3.29e-0838717417GO:0050807
GeneOntologyBiologicalProcessregulation of synapse structure or activity

RELN KIF1A MYO5B KALRN USP9X PPP1R9A CRTAC1 ADGRE2 ADNP SLIT2 PTPN13 NRXN1 NCAN SLIT1 NGEF LRP4 ELAVL2

4.42e-0839517417GO:0050803
GeneOntologyBiologicalProcesscell junction organization

RELN CEACAM5 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 CRTAC1 SPOCK2 ADGRE2 ADNP SHROOM2 SLIT2 GJA4 PTPN13 DST HMCN2 NRXN1 NCAN SLIT1 NGEF LRP4 ELAVL2 ILDR1 GJA10 TNR

4.96e-0897417427GO:0034330
GeneOntologyBiologicalProcesscell morphogenesis

RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 ADNP SHROOM2 WDR47 SLIT2 THBS4 DST LATS2 HMCN2 NRXN1 FEZ2 HECW2 ZNF335 SLIT1 NGEF LRP4 PDZD8 COBL ATF4 ARHGEF26 TNR PLXNA1 EPB41

7.18e-08119417430GO:0000902
GeneOntologyBiologicalProcessneuron projection morphogenesis

RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 ADNP WDR47 SLIT2 THBS4 DST HMCN2 NRXN1 FEZ2 HECW2 ZNF335 SLIT1 NGEF LRP4 COBL TNR PLXNA1

7.35e-0880217424GO:0048812
GeneOntologyBiologicalProcesssynapse organization

RELN KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 CRTAC1 SPOCK2 ADGRE2 ADNP SLIT2 PTPN13 HMCN2 NRXN1 NCAN SLIT1 NGEF LRP4 ELAVL2 GJA10 TNR

8.02e-0868517422GO:0050808
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 ADNP WDR47 SLIT2 THBS4 DST HMCN2 NRXN1 FEZ2 HECW2 ZNF335 SLIT1 NGEF LRP4 COBL TNR PLXNA1

1.08e-0781917424GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 ADNP WDR47 SLIT2 THBS4 DST HMCN2 NRXN1 FEZ2 HECW2 ZNF335 SLIT1 NGEF LRP4 COBL TNR PLXNA1

1.27e-0782617424GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 ADNP WDR47 SLIT2 DST HMCN2 NRXN1 FEZ2 HECW2 SLIT1 NGEF LRP4 COBL TNR PLXNA1

3.63e-0774817422GO:0048667
GeneOntologyBiologicalProcesssynapse assembly

RELN USP9X PPP1R9A CRTAC1 SPOCK2 ADGRE2 ADNP SLIT2 PTPN13 NRXN1 SLIT1 LRP4 ELAVL2 GJA10

3.75e-0730817414GO:0007416
GeneOntologyBiologicalProcessregulation of synapse assembly

USP9X PPP1R9A CRTAC1 ADGRE2 ADNP SLIT2 PTPN13 NRXN1 SLIT1 LRP4 ELAVL2

1.21e-0620217411GO:0051963
GeneOntologyBiologicalProcesspositive regulation of mRNA splicing, via spliceosome

RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F

1.79e-06441746GO:0048026
GeneOntologyBiologicalProcesspositive regulation of mRNA processing

RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F

3.42e-06491746GO:0050685
GeneOntologyBiologicalProcessactivation of GTPase activity

AGAP5 RALGAPA2 NGEF AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6

4.02e-061091748GO:0090630
GeneOntologyBiologicalProcessaxonogenesis

RELN MYO5B KALRN USP9X LAMA5 ADNP WDR47 SLIT2 DST HMCN2 NRXN1 FEZ2 SLIT1 LRP4 COBL TNR PLXNA1

6.41e-0656617417GO:0007409
GeneOntologyBiologicalProcesscell junction assembly

RELN USP9X PPP1R9A CRTAC1 SPOCK2 ADGRE2 ADNP SLIT2 GJA4 PTPN13 DST NRXN1 SLIT1 LRP4 ELAVL2 ILDR1 GJA10

6.87e-0656917417GO:0034329
GeneOntologyBiologicalProcessaxon development

RELN MYO5B KALRN USP9X LAMA5 CRTAC1 ADNP WDR47 SLIT2 DST HMCN2 NRXN1 FEZ2 SLIT1 LRP4 COBL TNR PLXNA1

8.69e-0664217418GO:0061564
GeneOntologyBiologicalProcessneuron projection development

FAT4 RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 CRTAC1 ADNP WDR47 SLIT2 THBS4 DST HMCN2 NRXN1 FEZ2 HECW2 ZNF335 SLIT1 NGEF LRP4 COBL PRMT1 TNR PLXNA1

1.03e-05128517427GO:0031175
GeneOntologyBiologicalProcesspositive regulation of RNA splicing

RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F

1.51e-05631746GO:0033120
GeneOntologyBiologicalProcessregulation of postsynapse organization

RELN KIF1A KALRN USP9X PPP1R9A NRXN1 NCAN NGEF LRP4

2.84e-051851749GO:0099175
GeneOntologyBiologicalProcessneuron development

FAT4 RELN HECW1 KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 CRTAC1 ADNP WDR47 SLIT2 THBS4 DST HMCN2 NRXN1 FEZ2 HECW2 ZNF335 SLIT1 NGEF LRP4 COBL PRMT1 TNR CNGB1 PLXNA1

3.78e-05146317428GO:0048666
GeneOntologyBiologicalProcessdendrite morphogenesis

RELN HECW1 KIF1A MYO5B KALRN PPP1R9A HECW2 NGEF LRP4

4.82e-051981749GO:0048813
GeneOntologyBiologicalProcessdendritic spine morphogenesis

RELN KIF1A MYO5B KALRN PPP1R9A NGEF

6.36e-05811746GO:0060997
GeneOntologyBiologicalProcessregulation of neuron projection development

RELN HECW1 KIF1A MYO5B KALRN PPP1R9A ADNP SLIT2 NRXN1 HECW2 SLIT1 NGEF LRP4 COBL TNR PLXNA1

6.46e-0561217416GO:0010975
GeneOntologyBiologicalProcessregulation of cell junction assembly

USP9X PPP1R9A CRTAC1 ADGRE2 ADNP SLIT2 PTPN13 NRXN1 SLIT1 LRP4 ELAVL2

6.59e-0530917411GO:1901888
GeneOntologyBiologicalProcesspostsynapse organization

RELN KIF1A MYO5B KALRN USP9X PPP1R9A LAMA5 NRXN1 NCAN NGEF LRP4

7.39e-0531317411GO:0099173
GeneOntologyBiologicalProcesspositive regulation of T-helper cell differentiation

RIPK2 MALT1 SOCS5 IL23R

1.29e-04311744GO:0045624
GeneOntologyBiologicalProcessregulation of GTPase activity

AGAP5 KALRN RALGAPA2 CBLB NGEF AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6 PLXNA1

1.35e-0433517411GO:0043087
GeneOntologyBiologicalProcessneuron projection guidance

RELN KALRN LAMA5 SLIT2 HMCN2 NRXN1 FEZ2 SLIT1 TNR PLXNA1

1.64e-0428617410GO:0097485
GeneOntologyBiologicalProcessprotein ubiquitination

ZSWIM8 RMND5A RNF168 HECW1 USP9X WWP1 RIPK2 KEAP1 CBLB UBOX5 UBR7 RNF43 MALT1 HECW2 SOCS5 N4BP1 BTRC MGRN1

1.79e-0481117418GO:0016567
GeneOntologyBiologicalProcessregulation of dendritic spine morphogenesis

RELN KIF1A KALRN PPP1R9A NGEF

2.06e-04641745GO:0061001
GeneOntologyBiologicalProcesschemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

2.11e-0431742GO:0021834
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

AGAP5 KALRN RALGAPA2 NGEF AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6

2.35e-042441749GO:0043547
GeneOntologyBiologicalProcessregulation of nervous system development

RELN MYO5B KALRN ADGRE2 ADNP SLIT2 PTPN13 NRXN1 ZNF335 NCAN SLIT1 LRP4 TNR PLXNA1 PCM1

2.78e-0462517415GO:0051960
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

ZSWIM8 RMND5A RNF168 HECW1 USP9X WWP1 RIPK2 KEAP1 CBLB MINDY2 UBOX5 UBR7 RNF43 MALT1 HECW2 SOCS5 N4BP1 USPL1 BTRC MGRN1

3.44e-04100917420GO:0070647
GeneOntologyBiologicalProcesstelencephalon cell migration

RELN WDR47 SLIT2 SLIT1 TNR

3.57e-04721745GO:0022029
GeneOntologyBiologicalProcessregulation of cell development

RELN PDE3A CEACAM5 MYO5B KALRN RIPK2 ADNP ZBTB1 SLIT2 MALT1 FBN1 ZNF335 NCAN SOCS5 SLIT1 LRP4 PRMT1 TNR PLXNA1 IL23R PCM1

3.77e-04109517421GO:0060284
GeneOntologyBiologicalProcessdorsal/ventral axon guidance

SLIT2 SLIT1

4.20e-0441742GO:0033563
GeneOntologyBiologicalProcessforebrain cell migration

RELN WDR47 SLIT2 SLIT1 TNR

4.32e-04751745GO:0021885
GeneOntologyBiologicalProcessdendritic spine organization

RELN KIF1A MYO5B KALRN PPP1R9A NGEF

4.35e-041151746GO:0097061
GeneOntologyBiologicalProcesspositive regulation of CD4-positive, alpha-beta T cell differentiation

RIPK2 MALT1 SOCS5 IL23R

5.57e-04451744GO:0043372
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

ZSWIM8 RMND5A RNF168 HECW1 USP9X WWP1 RIPK2 KEAP1 CBLB UBOX5 UBR7 RNF43 MALT1 HECW2 SOCS5 N4BP1 BTRC MGRN1

5.66e-0489317418GO:0032446
GeneOntologyBiologicalProcessdendrite development

RELN HECW1 KIF1A MYO5B KALRN PPP1R9A HECW2 NGEF LRP4 COBL

5.75e-0433517410GO:0016358
GeneOntologyBiologicalProcessembryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

6.96e-0451742GO:0021831
GeneOntologyBiologicalProcessaxon guidance

RELN KALRN LAMA5 SLIT2 HMCN2 NRXN1 FEZ2 SLIT1 TNR

7.26e-042851749GO:0007411
GeneOntologyBiologicalProcesspositive regulation of cell development

RELN PDE3A MYO5B KALRN RIPK2 ADNP ZBTB1 SLIT2 MALT1 ZNF335 NCAN SOCS5 PLXNA1 IL23R

7.34e-0461417414GO:0010720
GeneOntologyBiologicalProcessneuron projection organization

RELN KIF1A MYO5B KALRN PPP1R9A NGEF

7.36e-041271746GO:0106027
GeneOntologyBiologicalProcesspost-translational protein modification

ZSWIM8 RMND5A RNF168 HECW1 USP9X WWP1 RIPK2 KEAP1 CBLB MINDY2 UBOX5 UBR7 RNF43 MALT1 HECW2 SOCS5 N4BP1 USPL1 BTRC MGRN1

7.54e-04107417420GO:0043687
GeneOntologyBiologicalProcesspositive regulation of protein binding

USP9X RIPK2 NPHP3 MAVS EPB41

7.67e-04851745GO:0032092
GeneOntologyCellularComponentcollagen-containing extracellular matrix

RELN COMP DSPP LAMA5 SPOCK2 SLIT2 FBLN1 THBS3 THBS4 FBN1 DST HMCN2 HMCN1 NCAN MUC2 TNR

8.35e-0653017216GO:0062023
GeneOntologyCellularComponentextracellular matrix

RELN COMP DSPP LAMA5 SPOCK2 SLIT2 FBLN1 THBS3 THBS4 FBN1 DST HMCN2 HMCN1 ADAMTS7 NCAN MUC2 TNR

3.09e-0565617217GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

RELN COMP DSPP LAMA5 SPOCK2 SLIT2 FBLN1 THBS3 THBS4 FBN1 DST HMCN2 HMCN1 ADAMTS7 NCAN MUC2 TNR

3.21e-0565817217GO:0030312
GeneOntologyCellularComponentbasement membrane

LAMA5 FBLN1 THBS4 FBN1 DST HMCN2 HMCN1

6.84e-051221727GO:0005604
GeneOntologyCellularComponentsynapse-associated extracellular matrix

LAMA5 NCAN TNR

1.47e-04131723GO:0099535
GeneOntologyCellularComponentextracellular matrix of synaptic cleft

LAMA5 TNR

2.01e-0431722GO:0098965
GeneOntologyCellularComponentaxon

RELN KIF1A FSCN3 USP9X PPP1R9A CRTAC1 ADNP WDR47 SLIT2 DST HMCN2 NRXN1 FEZ2 NGEF COBL EEA1 CNGB1 UNC80

4.10e-0489117218GO:0030424
GeneOntologyCellularComponentgrowth cone

FSCN3 USP9X PPP1R9A CRTAC1 WDR47 NRXN1 NGEF COBL

9.84e-042451728GO:0030426
GeneOntologyCellularComponentcell cortex

MYO5B PPP1R9A PARD3B STOX1 SHROOM2 DST HMCN2 HMCN1 COBL EPB41

1.04e-0337117210GO:0005938
GeneOntologyCellularComponentsite of polarized growth

FSCN3 USP9X PPP1R9A CRTAC1 WDR47 NRXN1 NGEF COBL

1.21e-032531728GO:0030427
MousePhenofused cornea and lens

AGAP5 RNF168 AGAP9 AGAP7P AGAP4 AGAP6

8.85e-08241366MP:0001307
MousePhenoabnormal ureteric bud morphology

FAT4 TCF21 DSPP LAMA5 SLIT2 LRP4

1.83e-05571366MP:0006032
MousePhenoabsent pinna reflex

AGAP5 WDR47 ILDR1 AGAP9 AGAP7P AGAP4 AGAP6

2.51e-05891367MP:0006358
MousePhenoabnormal centrosome morphology

CHORDC1 LATS2 COBL BTRC

3.68e-05201364MP:0030943
MousePhenomesocardia

PCSK5 LAMA5 ODAD2 MGRN1

3.68e-05201364MP:0000650
MousePhenoabnormal microtubule organizing center morphology

CHORDC1 LATS2 COBL BTRC

5.47e-05221364MP:0030942
MousePhenoabnormal pinna reflex

AGAP5 WDR47 ILDR1 AGAP9 AGAP7P AGAP4 AGAP6

5.68e-051011367MP:0001485
MousePhenoabnormal lens development

AGAP5 RNF168 AGAP9 AGAP7P AGAP4 AGAP6

1.10e-04781366MP:0005545
DomainEGF-like_dom

PCSK5 FAT4 RELN COMP LAMA5 CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4 TNR

1.16e-1324916920IPR000742
DomainEGF_Ca-bd_CS

FAT4 COMP CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NCAN SLIT1 LRP4

2.09e-139716914IPR018097
DomainEGF_CA

FAT4 COMP CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NCAN SLIT1 LRP4

2.79e-139916914PS01187
DomainEGF_1

FAT4 RELN COMP LAMA5 CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4 TNR

1.88e-1225516919PS00022
DomainEGF-like_CS

FAT4 RELN COMP LAMA5 CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4 TNR

2.84e-1226116919IPR013032
DomainEGF_2

FAT4 RELN COMP LAMA5 CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4 TNR

3.72e-1226516919PS01186
DomainEGF

PCSK5 FAT4 RELN COMP LAMA5 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4 TNR

4.68e-1223516918SM00181
DomainEGF_3

FAT4 RELN COMP CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4 TNR

4.68e-1223516918PS50026
DomainEGF_CA

FAT4 COMP CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NCAN SLIT1 LRP4

5.26e-1212216914SM00179
DomainEGF-like_Ca-bd_dom

FAT4 COMP CRTAC1 ADGRE2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NCAN SLIT1 LRP4

6.58e-1212416914IPR001881
DomainEGF_CA

FAT4 COMP CRTAC1 ADGRE2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 LRP4

3.27e-108616911PF07645
DomainGrowth_fac_rcpt_

PCSK5 FAT4 COMP LAMA5 ADGRE2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 SLIT1 LRP4

1.74e-0915616913IPR009030
DomainRBM1CTR

RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F

3.13e-0981695PF08081
DomainRBM1CTR

RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F

3.13e-0981695IPR012604
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 ADGRE2 SLIT2 FBLN1 FBN1 HMCN2 HMCN1 NRXN1 NCAN SLIT1 LRP4

3.18e-0910616911IPR000152
DomainASX_HYDROXYL

FAT4 ADGRE2 SLIT2 FBLN1 FBN1 HMCN2 HMCN1 NRXN1 NCAN LRP4

2.42e-0810016910PS00010
Domain-

PAPPA2 FAT4 COMP LAMA5 SLIT2 THBS3 THBS4 NRXN1 SLIT1

1.98e-079516992.60.120.200
DomainCOMP

COMP THBS3 THBS4

7.28e-0731693PF11598
DomainThbs/COMP_coiled-coil

COMP THBS3 THBS4

7.28e-0731693IPR024665
DomainLaminin_G

FAT4 LAMA5 SLIT2 THBS3 THBS4 NRXN1 SLIT1

8.94e-07581697IPR001791
DomainArfGap

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

5.69e-06291695SM00105
DomainARFGAP

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

5.69e-06291695PS50115
DomainArfGap

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

5.69e-06291695PF01412
DomainArfGAP

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

5.69e-06291695IPR001164
DomainTSP_3

COMP THBS3 THBS4

7.18e-0651693PF02412
DomainTSP3

COMP THBS3 THBS4

7.18e-0651693PS51234
DomainTSP_CTER

COMP THBS3 THBS4

7.18e-0651693PS51236
DomainThrombospondin_3_rpt

COMP THBS3 THBS4

7.18e-0651693IPR017897
DomainTSP_type-3_rpt

COMP THBS3 THBS4

7.18e-0651693IPR028974
Domain-

COMP THBS3 THBS4

7.18e-06516934.10.1080.10
DomainThrombospondin_C

COMP THBS3 THBS4

7.18e-0651693IPR008859
DomainTSP_C

COMP THBS3 THBS4

7.18e-0651693PF05735
DomainThrombospondin_3-like_rpt

COMP THBS3 THBS4

7.18e-0651693IPR003367
DomainAlpha_kinase

TRPM6 ALPK1 ALPK2

1.43e-0561693PF02816
DomainMHCK_EF2_kinase

TRPM6 ALPK1 ALPK2

1.43e-0561693IPR004166
DomainALPHA_KINASE

TRPM6 ALPK1 ALPK2

1.43e-0561693PS51158
DomainAlpha_kinase

TRPM6 ALPK1 ALPK2

1.43e-0561693SM00811
DomainEGF

SLIT2 THBS4 HMCN1 NRXN1 BTC NCAN SLIT1 LRP4

1.93e-051261698PF00008
DomainLAM_G_DOMAIN

FAT4 LAMA5 SLIT2 NRXN1 SLIT1

2.25e-05381695PS50025
DomainLaminin_G_2

FAT4 LAMA5 SLIT2 NRXN1 SLIT1

2.91e-05401695PF02210
DomainLamG

FAT4 LAMA5 SLIT2 NRXN1 SLIT1

4.67e-05441695SM00282
DomainStorkhead-box_winged-helix

STOX1 STOX2

8.14e-0521692IPR019391
DomainHECW_N

HECW1 HECW2

8.14e-0521692IPR032348
DomainStork_head

STOX1 STOX2

8.14e-0521692PF10264
DomainHECW_N

HECW1 HECW2

8.14e-0521692PF16562
DomaincEGF

FBLN1 FBN1 HMCN1 LRP4

8.28e-05261694PF12662
DomaincEGF

FBLN1 FBN1 HMCN1 LRP4

8.28e-05261694IPR026823
DomainConA-like_dom

PAPPA2 FAT4 COMP LAMA5 SLIT2 THBS3 THBS4 NRXN1 SLIT1

1.76e-042191699IPR013320
DomainG2F

HMCN2 HMCN1

4.83e-0441692PF07474
DomainNIDOGEN_G2

HMCN2 HMCN1

4.83e-0441692PS50993
DomainGFP

HMCN2 HMCN1

4.83e-0441692IPR009017
DomainG2_nidogen/fibulin_G2F

HMCN2 HMCN1

4.83e-0441692IPR006605
DomainPH_dom-like

AGAP5 KIF1A KALRN PTPN13 NGEF PLCB3 AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6 EPB41

5.15e-0442616912IPR011993
DomainCTCK_1

SLIT2 SLIT1 MUC2

5.37e-04181693PS01185
DomainWW

HECW1 WWP1 FNBP4 HECW2

8.52e-04471694PF00397
Domain-

AGAP5 KIF1A KALRN PTPN13 NGEF PLCB3 AGAP9 ARHGEF26 AGAP4 AGAP6 EPB41

8.88e-04391169112.30.29.30
DomainWW

HECW1 WWP1 FNBP4 HECW2

9.23e-04481694SM00456
DomainCT

SLIT2 SLIT1 MUC2

9.88e-04221693SM00041
DomainPH

AGAP5 KIF1A KALRN NGEF AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6

9.91e-042781699SM00233
DomainPH_DOMAIN

AGAP5 KIF1A KALRN NGEF AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6

1.02e-032791699PS50003
DomainPH_domain

AGAP5 KIF1A KALRN NGEF AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6

1.04e-032801699IPR001849
DomainWW_DOMAIN_1

HECW1 WWP1 FNBP4 HECW2

1.16e-03511694PS01159
DomainWW_DOMAIN_2

HECW1 WWP1 FNBP4 HECW2

1.16e-03511694PS50020
DomainWW_dom

HECW1 WWP1 FNBP4 HECW2

1.25e-03521694IPR001202
DomainCys_knot_C

SLIT2 SLIT1 MUC2

1.45e-03251693IPR006207
DomainCTCK_2

SLIT2 SLIT1 MUC2

1.45e-03251693PS01225
DomainHECT

HECW1 WWP1 HECW2

1.81e-03271693PF00632
DomainHECTc

HECW1 WWP1 HECW2

1.81e-03271693SM00119
DomainHECT_dom

HECW1 WWP1 HECW2

1.81e-03271693IPR000569
DomainHECT

HECW1 WWP1 HECW2

1.81e-03271693PS50237
DomainhEGF

FAT4 SLIT2 SLIT1

2.02e-03281693PF12661
DomainCTLH

RMND5A WDR47

2.81e-0391692SM00668
PathwayREACTOME_ECM_PROTEOGLYCANS

COMP DSPP LAMA5 NCAN LRP4 TNR

3.06e-05761126M27219
PathwayKEGG_ECM_RECEPTOR_INTERACTION

RELN COMP LAMA5 THBS3 THBS4 TNR

5.40e-05841126M7098
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COMP DSPP LAMA5 FBLN1 FBN1 DST NRXN1 NCAN LRP4 TNR

1.37e-0430011210M610
Pubmed

A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F

1.11e-13717768269511
Pubmed

Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.

RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F

1.44e-111217769598316
Pubmed

RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.

RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F

1.93e-116177515184870
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AGAP5 ZSCAN12 FNBP4 LAMA5 ICE1 KEAP1 ADNP NCAPH STOX2 DST ABCA5 HECW2 LRP4 AGAP9 AGAP7P AGAP4 AGAP6 ZNF646 MGRN1

3.55e-115291771914621295
Pubmed

Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.

RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F

6.72e-11717758875892
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ZSCAN12 TCF20 HECW1 KALRN USP9X PPP1R9A RIPK2 KEAP1 ADNP ZBTB1 WDR47 STOX2 DST NRXN1 N4BP2 KIAA1217 NCAN NGEF ELAVL2 PRMT1 ARHGEF26 TNR PCM1 GOLGB1

1.58e-109631772428671696
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

4.00e-109177512640130
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

7.96e-1010177520664521
Pubmed

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

USP9X RBMY1A1 RBMY1D RBMY1B RBMY1E

7.96e-101017759384609
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.45e-0911177515381706
Pubmed

An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.23e-09517748817321
Pubmed

Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.23e-095177420016065
Pubmed

The role of human and mouse Y chromosome genes in male infertility.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.23e-095177411097427
Pubmed

Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.23e-095177419737860
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

4.02e-0913177527713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

6.22e-0914177522453919
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

USP9X RBMY1A1 RBMY1D RBMY1B RBMY1E

9.30e-0915177514762062
Pubmed

Identification of target messenger RNA substrates for mouse RBMY.

RBMY1A1 RBMY1D RBMY1B RBMY1E

9.65e-096177418492746
Pubmed

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.

RBMY1A1 RBMY1D RBMY1B RBMY1E

9.65e-096177412356914
Pubmed

Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.

RBMY1A1 RBMY1D RBMY1B RBMY1E

9.65e-09617749499427
Pubmed

The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.

RBMY1A1 RBMY1D RBMY1B RBMY1E

9.65e-096177418239052
Pubmed

Does Rbmy have a role in sperm development in mice?

RBMY1A1 RBMY1D RBMY1B RBMY1E

9.65e-096177415051956
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

AGAP5 KIF1A KALRN AZI2 CBLB STOX2 AGAP9 AGAP7P AGAP4 AGAP6 PCM1

1.79e-082181771133378226
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EHBP1 AFTPH TCF20 CEP85L KCTD8 RIPK2 PARD3B FAM117B ALPK1 ARFGEF3 STOX2 PTPN13 DST RESF1 N4BP2 KIAA1217 COBL EPB41 PCM1 GOLGB1

1.92e-088611772036931259
Pubmed

The roles of RNA-binding proteins in spermatogenesis and male infertility.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.24e-087177410377282
Pubmed

RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.24e-087177417001072
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

USP9X RBMY1A1 RBMY1D RBMY1B RBMY1E

2.62e-0818177512023983
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

EHBP1 TCF20 ZSCAN4 ICE1 KEAP1 ADNP ZBTB1 ZNF8 PTPN13 DST RESF1 N4BP2 PCM1 GOLGB1

3.59e-084181771434709266
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZSWIM8 RELN KIF1A KALRN CNST CEP85L USP9X CRTAC1 SPOCK2 NCKAP5 SHROOM2 WDR47 PTPN13 FBN1 DST ZNF660 NGEF NAV3 LRP4 PDZD8 USPL1 TXLNG BTRC PCM1

4.29e-0812851772435914814
Pubmed

Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.47e-08817747479793
Pubmed

Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.

COMP THBS3 THBS4

1.30e-073177333910854
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.33e-0710177410601091
Pubmed

The role of Dby mRNA in early development of male mouse zygotes.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.11e-0712177420543856
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

AGAP5 USP9X KCTD8 STOX1 WDR47 PTPN13 NCAN ELAVL2 AGAP9 AGAP7P TNR AGAP4 AGAP6

3.61e-074301771332581705
Pubmed

GASZ promotes germ cell derivation from embryonic stem cells.

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.47e-0713177423816659
Pubmed

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.

RBMY1A1 RBMY1C RBMY1B RBMY1F

4.47e-0713177410749975
Pubmed

Absence of mDazl produces a final block on germ cell development at meiosis.

RBMY1A1 RBMY1D RBMY1B RBMY1E

6.24e-0714177414611631
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

EHBP1 RBMY1A1 FAM114A2 GPATCH4 KEAP1 CHORDC1 TRAPPC8 NDRG3 SLIT2 EDEM3 PTPN13 MAVS GORAB PDZD8 N4BP1 TXLNG EPB41 PCM1 GOLGB1

1.05e-0610071771934597346
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ZSWIM8 HECW1 MYO5B WWP1 LAMA5 SLIT2 FBLN1 FBN1 SLIT1 COBL PRMT1 KAZN AGAP7P USPL1

1.22e-065601771421653829
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

COMP THBS3 THBS4

1.29e-065177330622267
Pubmed

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

COMP THBS3 THBS4

1.29e-065177318467703
Pubmed

Loss of maternal Trim28 causes male-predominant early embryonic lethality.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.47e-0617177428115466
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EHBP1 HECW1 MYO5B ALPK1 TRAPPC8 RALGAPA2 RGL1 NPHP3 N4BP2 SOCS5 N4BP1 KAZN UNC80

1.66e-064931771315368895
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

AGAP5 KALRN USP9X PPP1R9A NCAN AGAP9 AGAP7P TNR AGAP4 AGAP6

1.98e-062811771028706196
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

EHBP1 KIF1A WWP1 PPP1R9A FNBP4 PARD3B FAM117B SHROOM2 DNAH14 PCNX2 ARFGEF3 BPTF MALT1 PTPN13 LATS2 KIAA1217 NGEF COBL ARHGEF26 EPB41 PCM1 GOLGB1 MGRN1

2.24e-0614891772328611215
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

AGAP5 MINDY2 PCNX2 ADAMTS7 AGAP9 AGAP4 AGAP6

2.30e-06116177730652415
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

HECW1 WWP1 HECW2 BTRC

2.37e-0619177421572392
Pubmed

Alpha-kinases: a new class of protein kinases with a novel catalytic domain.

TRPM6 ALPK1 ALPK2

2.56e-066177310021370
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

PCSK5 ZSWIM8 FAT4 GCFC2 HECW1 MYO5B KALRN WWP1 MAGEB18 UBR7 FBLN1 SLIT1 PRMT1 KAZN

3.17e-066081771416713569
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

HECW1 WWP1 HECW2 BTRC

3.63e-0621177437005481
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 WWP1 GPATCH4 KEAP1 RALGAPA2 RNF43 ZNF711 ZNF8 SLIT2 EDEM3 BPTF MALT1 RESF1 HMCN2 LRP4 MMS19 UNC80 PCM1 ZNF646

4.67e-0611161771931753913
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

MYO5B FNBP4 SPOCK2 DST RESF1 NRXN1 LRP4

4.90e-06130177712421765
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

ZSWIM8 USP9X WWP1 LAMA5 ARFGEF3 SLIT2 PTPN13 NPHP3 HECW2 MMS19

5.16e-063131771038270169
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ZSWIM8 ZSCAN12 KIF1A KALRN USP9X ALPK1 ARFGEF3 SLIT2 ASXL3 ZNF335 MUC2 UNC80 PCM1

5.66e-065521771310737800
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EHBP1 AFTPH PARG FAM114A2 GPATCH4 ICE1 KEAP1 ADNP NCAPH PTPN13 DST MAVS KIAA1217 PRMT1 EPB41 PCM1 GOLGB1

6.42e-069341771733916271
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

ZSWIM8 KIF1A KALRN USP9X SLIT2 SLIT1 NGEF NAV3 ELAVL2 PLCB3 BTRC PCM1

6.49e-064751771231040226
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

COMP THBS3 THBS4

7.12e-068177324460873
Pubmed

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.

SLIT2 SLIT1 PLXNA1

7.12e-068177325485759
Pubmed

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.

RELN COMP SLIT2

7.12e-068177316774856
Pubmed

A human MAP kinase interactome.

EHBP1 TCF20 NCKAP5 CBLB RGL1 DST N4BP2 NAV3 COBL ATF4 TXLNG GOLGB1

8.16e-064861771220936779
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

AFTPH CEP85L TUT7 PKD1L1 PARD3B AZI2 CHORDC1 MAVS IQCC N4BP2 KIAA1217 COBL TXLNG CEP97 EPB41 PCM1

8.38e-068531771628718761
Pubmed

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.

RBMY1A1 RBMY1D RBMY1B RBMY1E

8.88e-0626177435920200
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

EHBP1 TCF20 RNF43 STOX2 PTPN13 LATS2 KIAA1217 N4BP1 GOLGB1

8.93e-06263177934702444
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

RBMY1A1 RBMY1D RBMY1B RBMY1E ZNF711

9.13e-0655177519468303
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

RBMY1A1 RBMY1D RBMY1B RBMY1E GPATCH4 EEA1

9.53e-0695177624029230
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

EHBP1 PPP1R9A PARD3B RALGAPA2 CBLB PTPN13 DST KIAA1217 GORAB COBL GOLGB1

1.16e-054211771136976175
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 RMND5A RNF168 TCF21 ZSCAN4 WWP1 FNBP4 LAMA5 KEAP1 CBLB FBLN1 DST GOLGB1

1.17e-055911771315231748
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

AFTPH KEAP1 ARFGEF3 PTPN13 DST COBL CEP97 PCM1

1.27e-05209177836779422
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

AGAP5 FAT4 MINDY2 DST TCP11L2 ASXL3 KIAA1217 AGAP7P USPL1 SPAG17 AGAP4 ALPK2

1.40e-055131771225798074
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FNBP4 ICE1 TRAPPC8 ZBTB1 RGL1 NAV3

1.43e-05102177610231032
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMA5 FBLN1 THBS4 FBN1 HMCN2 HMCN1 MUC2

2.51e-05167177722159717
Pubmed

Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration.

COMP ADAMTS7

2.58e-052177238528617
Pubmed

Upregulation of ADAMTS‑7 and downregulation of COMP are associated with aortic aneurysm.

COMP ADAMTS7

2.58e-052177228849199
Pubmed

ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein.

COMP ADAMTS7

2.58e-052177216585064
Pubmed

FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic mice.

ATF4 TXLNG

2.58e-052177215911876
Pubmed

Association between Genetic Polymorphisms of Inflammatory Response Genes and Acute Pancreatitis.

RIPK2 IL23R

2.58e-052177231044631
Pubmed

Cultured human retinal pigment epithelial cells differentially express thrombospondin-1, -2, -3, and -4.

THBS3 THBS4

2.58e-052177211137453
Pubmed

COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.

COMP THBS4

2.58e-052177230464261
Pubmed

Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis.

RBMY1A1 RBMY1B

2.58e-052177232473614
Pubmed

Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex.

SLIT2 SLIT1

2.58e-052177212515855
Pubmed

Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes.

SLIT2 SLIT1

2.58e-052177212200164
Pubmed

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.

HMCN2 HMCN1

2.58e-052177232035013
Pubmed

PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes.

PRMT1 ATF4

2.58e-052177231787756
Pubmed

Directional guidance of neuronal migration in the olfactory system by the protein Slit.

SLIT2 SLIT1

2.58e-052177210432110
Pubmed

LACC1 Promoted Nerve Injury in an Anesthesia-Induced Cognitive Disorder Model via RIP2 Expression through ROS-NOD2 Induction.

RIPK2 LACC1

2.58e-052177238064597
Pubmed

STOX2 but not STOX1 is differentially expressed in decidua from pre-eclamptic women: data from the Second Nord-Trondelag Health Study.

STOX1 STOX2

2.58e-052177220643876
Pubmed

Lymph node CEA and MUC2 mRNA as useful predictors of outcome in colorectal cancer.

CEACAM5 MUC2

2.58e-052177221618511
Pubmed

Upregulation of ADAMTS‑7 and downregulation of COMP are associated with spontaneous abortion.

COMP ADAMTS7

2.58e-052177230720083
Pubmed

TXLNG improves insulin resistance in obese subjects in vitro and in vivo by inhibiting ATF4 transcriptional activity.

ATF4 TXLNG

2.58e-052177237028586
Pubmed

Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2(-/-) as well as Slit1(-/-)Slit2(-/-) embryos.

SLIT2 SLIT1

2.58e-052177223320558
Pubmed

Slit1 and slit2 proteins control the development of the lateral olfactory tract.

SLIT2 SLIT1

2.58e-052177212097499
Pubmed

N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.

MALT1 N4BP1

2.58e-052177231133753
Pubmed

Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.

RELN SLIT2 SLIT1

2.76e-0512177316540508
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN1 RESF1 NRXN1 KIAA1217 UNC80

3.20e-0571177533541421
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

RELN LAMA5 SPOCK2 SLIT2 FBN1 HMCN2 HMCN1

3.38e-05175177728071719
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

EHBP1 WWP1 PPP1R9A RALGAPA2 NDRG3 LATS2 COBL PLCB3 ARHGEF26 TXLNG PLXNA1 EPB41

3.84e-055691771230639242
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

TCF20 FBN1 DST RESF1 MAVS NGEF

4.14e-05123177626912792
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYCL PCSK5 KALRN WWP1 LAMA5 ICE1 RALGAPA2 RNF43 PCNX2 DST LATS2 ADAMTS7 ZNF335 LRP4 PDZD8 COBL PLXNA1

5.39e-0511051771735748872
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

PAPPA2 PCSK5 VGLL2 TUT7 NCKAP5 SOCS5 SPAG17

7.38e-05198177720881960
Pubmed

Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.

HMCN2 HMCN1

7.70e-053177212388743
InteractionILDR1 interactions

HECW1 WWP1 HECW2 ILDR1

1.77e-06111764int:ILDR1
CytobandYq11.223

RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F

3.18e-05931775Yq11.223
Cytoband10q11.23

PARG AGAP7P AGAP6

2.82e-0433177310q11.23
CytobandEnsembl 112 genes in cytogenetic band chr1q25

PAPPA2 EDEM3 RGL1 HMCN1 TNR

4.96e-041671775chr1q25
Cytoband4q21.3

DSPP PTPN13

7.95e-041117724q21.3
CytobandEnsembl 112 genes in cytogenetic band chr10q11

PARG AGAP9 AGAP7P AGAP4 AGAP6

8.46e-041881775chr10q11
Cytoband8q21

WWP1 RIPK2

9.51e-041217728q21
GeneFamilyArfGAPs

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.58e-06331105395
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP5 AGAP9 AGAP4 AGAP6

2.90e-061711041291
GeneFamilyFibulins

FBLN1 HMCN2 HMCN1

1.20e-0581103556
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AGAP5 KIF1A AGAP9 AGAP7P ARHGEF26 AGAP4 AGAP6

2.66e-042061107682
GeneFamilyRNA binding motif containing

RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F ELAVL2

3.26e-042131107725
GeneFamilyPDZ domain containing

PPP1R9A PARD3B SHROOM2 PTPN13 PDZD8

2.37e-0315211051220
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CEACAM5 KALRN HMCN2 HMCN1 ALPK2

3.04e-031611105593
CoexpressionNABA_CORE_MATRISOME

RELN COMP DSPP LAMA5 SPOCK2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NCAN SLIT1 TNR

4.44e-1027017515MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN COMP DSPP LAMA5 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 SLIT1 TNR

5.68e-1019117513MM17059
CoexpressionNABA_CORE_MATRISOME

RELN COMP DSPP LAMA5 SPOCK2 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 NCAN SLIT1 TNR

5.72e-1027517515M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

RELN COMP DSPP LAMA5 SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 SLIT1 TNR

7.81e-1019617513M3008
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

RELN KIF1A CEP85L PPP1R9A LAMA5 FAM114A2 SPOCK2 FAM117B SHROOM2 ARFGEF3 STOX2 NRXN1 N4BP2 ASXL3 NCAN NGEF NAV3 ELAVL2 EEA1 SPAG17 MUC2 PLXNA1 EPB41 CALN1 CCDC144A

9.77e-08110617525M39071
CoexpressionNABA_MATRISOME

PAPPA2 PCSK5 RELN COMP DSPP LAMA5 SPOCK2 CLEC4M SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 ADAMTS7 BTC NCAN SLIT1 MUC2 TNR PLXNA1

1.10e-06100817522MM17056
CoexpressionNABA_MATRISOME

PAPPA2 PCSK5 RELN COMP DSPP LAMA5 SPOCK2 CLEC4M SLIT2 FBLN1 THBS3 THBS4 FBN1 HMCN2 HMCN1 ADAMTS7 BTC NCAN SLIT1 MUC2 TNR PLXNA1

1.47e-06102617522M5889
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN

AVL9 WWP1 SLIT2 MALT1 DST NAV3 BTRC

1.67e-06851757M10575
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

4.59e-06371755MM1121
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EHBP1 AVL9 USP9X WWP1 PARG TRAPPC8 ADNP CBLB SLIT2 BPTF RGL1 MALT1 PTPN13 DST SOCS5 NAV3 N4BP1 KAZN BTRC

4.95e-0685617519M4500
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.10e-05441755MM485
CoexpressionCUI_TCF21_TARGETS_2_DN

TCF21 CEP85L USP9X TUT7 PARD3B ADGRE2 CBLB SHROOM2 MINDY2 ARFGEF3 EDEM3 MALT1 DST LATS2 TCP11L2 ABCA5 HECW2 ARHGEF26

2.98e-0588817518MM1018
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

PCSK5 USP9X WWP1 TUT7 CHORDC1 TRAPPC8 BPTF STOX2 PTPN13 RESF1 ABCA5 EEA1 ZNF654 PCM1 GOLGB1

3.68e-0565617515M18979
CoexpressionBUSSLINGER_GASTRIC_G_CELLS

KIF1A ARFGEF3 BPTF DST ABCA5 LRP4

5.15e-05981756M40018
CoexpressionBROWNE_HCMV_INFECTION_30MIN_DN

ZSCAN12 KALRN NCAPH GJA4 DST EEA1 USPL1

5.58e-051451757M0
CoexpressionCUI_TCF21_TARGETS_2_DN

TCF21 CEP85L USP9X TUT7 PARD3B CBLB SHROOM2 MINDY2 ARFGEF3 EDEM3 MALT1 DST LATS2 TCP11L2 ABCA5 HECW2 ARHGEF26

6.25e-0585417517M1533
CoexpressionGSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN

ZSCAN12 KIF1A AVL9 WWP1 TCP11L2 NGEF LRP4 N4BP1

6.25e-052001758M8110
CoexpressionGSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP

TCF20 AVL9 RIPK2 CBLB NDRG3 WDR47 BPTF PDZD8

6.25e-052001758M3251
CoexpressionGSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN

PAPPA2 KIF1A TUT7 GPATCH4 TRAPPC8 ADNP MMS19 TXLNG

6.25e-052001758M4994
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP

ZSCAN12 USP9X WWP1 LDLRAD3 ARFGEF3 TCP11L2 PDZD8 EEA1

6.25e-052001758M6629
CoexpressionGSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP

MYCL PCSK5 RELN FNBP4 ZNF711 FBLN1 PCM1 GOLGB1

6.25e-052001758M5261
CoexpressionCHEN_ETV5_TARGETS_TESTIS

RBMY1A1 RBMY1D RBMY1B RBMY1E

6.75e-05331754MM701
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

KIF1A KALRN C6orf89 NAA11 RBMY1A1 TUT7 RBMY1D RBMY1B RBMY1E CRTAC1 MALT1 ZNF660 RBMY1F PDZD8 KAZN BTRC CALN1

8.17e-0587317517M16009
CoexpressionKARLSSON_TGFB1_TARGETS_DN

AGAP5 LAMA5 AZI2 PTPN13 AGAP9 AGAP7P AGAP4 AGAP6

8.50e-052091758MM1058
CoexpressionGSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN

AFTPH TUT7 AZI2 KEAP1 HMCN2 FEZ2 IL23R

1.21e-041641757M6859
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

RELN RMND5A TCF20 RIPK2 FNBP4 AZI2 CHORDC1 CBLB WDR47 RGL1 DST RESF1 N4BP1 ATF4 USPL1 GOLGB1

1.34e-0482217516M6782
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

PPP1R9A PARD3B NCKAP5 DNAH14 STOX2 KIAA1217 ALPK2

1.87e-041761757M39223
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN HECW1 KALRN ODAD2 ARFGEF3 HMCN1 NRXN1 ASXL3 NAV3 SPAG17 UNC80

9.35e-12184174122cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN HECW1 KALRN ODAD2 ARFGEF3 HMCN1 NRXN1 ASXL3 NAV3 SPAG17 UNC80

9.35e-1218417412ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN HECW1 KALRN ODAD2 ARFGEF3 HMCN1 NRXN1 ASXL3 NAV3 SPAG17 UNC80

9.35e-12184174122b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 PDE3A TCF21 KALRN LDLRAD3 SLIT2 FBLN1 FBN1 DST HMCN1 KAZN

3.90e-101981741121cf4d81386761d09d0f6829c01c198e5524176d
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

FAT4 COMP HECW1 SLIT2 FBLN1 FBN1 DST HMCN1 NAV3 KAZN

4.89e-0919317410e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 TCF21 KALRN LDLRAD3 SLIT2 FBLN1 FBN1 DST HMCN1 KAZN

5.14e-0919417410011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B PPP1R9A PARD3B NCKAP5 DNAH14 ARFGEF3 STOX2 PTPN13 COBL ARHGEF26

5.14e-091941741053f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

FAT4 PDE3A TCF21 SLIT2 FBLN1 FBN1 DST HMCN1 NAV3 KAZN

6.56e-09199174104bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B LAMA5 PARD3B SPOCK2 NCKAP5 STOX2 DST COBL ARHGEF26

4.81e-08184174957c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B LAMA5 PARD3B SPOCK2 NCKAP5 STOX2 DST COBL ARHGEF26

4.81e-081841749d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

MYO5B PPP1R9A PARD3B CRTAC1 NCKAP5 ARFGEF3 PTPN13 KIAA1217 COBL

5.28e-0818617493006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

FAT4 PDE3A HECW1 SLIT2 FBLN1 FBN1 DST HMCN1 NAV3

5.53e-081871749bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

MYO5B PPP1R9A PARD3B DNAH14 ARFGEF3 STOX2 PTPN13 KIAA1217 COBL

6.93e-081921749efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

EHBP1 PCSK5 PARD3B PCNX2 SLIT2 FBLN1 FBN1 HMCN2 KAZN

7.91e-081951749a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO5B PPP1R9A PARD3B NCKAP5 DNAH14 ARFGEF3 STOX2 PTPN13 COBL

7.91e-0819517499406866f99555198a9be311fbd65751b70f35446
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1A USP9X DST NRXN1 ABCA5 UNC80 PCM1 GOLGB1

7.91e-0819517497796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

PDE3A PARD3B SLIT2 FBLN1 FBN1 DST HMCN1 NAV3 KAZN

8.63e-081971749fb847f2277609c31fffcdf49517243ce0684facf
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 PDE3A TCF21 SLIT2 FBLN1 PTPN13 FBN1 HMCN1 KAZN

9.01e-081981749bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HECW1 PPP1R9A CRTAC1 THBS4 NRXN1 KIAA1217 LRP4 TNR UNC80

9.41e-08199174919a97e27a4758e794ce7246d295e112b47931a48
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 PPP1R9A NCKAP5 RALGAPA2 BPTF DST RESF1 HMCN1 KIAA1217

9.82e-082001749dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5B PPP1R9A SLC12A8 ITPRID1 RALGAPA2 ARFGEF3 STOX2 KIAA1217 COBL

9.82e-0820017490eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellControl|World / group, cell type (main and fine annotations)

CEACAM5 MYO5B PPP1R9A PARD3B NCKAP5 ARFGEF3 STOX2 COBL

3.34e-071681748a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

MYO5B PPP1R9A LAMA5 PARD3B NCKAP5 STOX2 COBL ARHGEF26

5.42e-071791748a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

KALRN F2RL3 LAMA5 NCKAP5 ITPRID1 SHROOM2 HECW2 KIAA1217

5.89e-071811748c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

MYO5B PPP1R9A SPOCK2 NCKAP5 DNAH14 STOX2 COBL ARHGEF26

6.40e-071831748942530449e9c6583705eeb8f6f12621daea57252
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

FAT4 RFTN2 SLIT2 RGL1 HMCN1 SOCS5 NAV3 EEA1

6.67e-07184174867164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

CEACAM5 LAMA5 SPOCK2 NCKAP5 DST COBL ARHGEF26 PLXNA1

6.67e-071841748cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CEACAM5 LAMA5 SPOCK2 NCKAP5 DST COBL ARHGEF26 PLXNA1

6.67e-071841748bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5B LAMA5 SPOCK2 SLC12A8 NCKAP5 DST COBL ARHGEF26

6.95e-0718517481c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PDE3A TCF21 NCKAP5 FBLN1 STOX2 FBN1 DST UNC80

6.95e-0718517489f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

MYO5B LAMA5 SPOCK2 SLC12A8 NCKAP5 STOX2 COBL ARHGEF26

7.24e-07186174809d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCSK5 CBLB PCNX2 SLIT2 FBLN1 FBN1 HMCN2 KAZN

7.54e-0718717484ea486991f66c29728d127171a07b81404ec0b78
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5B LAMA5 SPOCK2 SLC12A8 NCKAP5 DST COBL ARHGEF26

7.54e-071871748d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

MYO5B LAMA5 PARD3B NCKAP5 STOX2 DST COBL ARHGEF26

7.54e-07187174877f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PDE3A RFTN2 LDLRAD3 RGL1 FBLN1 FBN1 DST

8.84e-071911748c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1A SPOCK2 ARFGEF3 DST NRXN1 UNC80 GOLGB1

8.84e-0719117483387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PDE3A RFTN2 LDLRAD3 RGL1 FBLN1 FBN1 DST

8.84e-071911748cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

MYO5B PPP1R9A LAMA5 DNAH14 STOX2 PTPN13 KIAA1217 COBL

8.84e-071911748d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5B PPP1R9A DNAH14 ARFGEF3 STOX2 PTPN13 KIAA1217 COBL

8.84e-071911748e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT4 PARD3B SLIT2 FBLN1 FBN1 DST HMCN1 NAV3

8.84e-0719117486688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

MYO5B PPP1R9A DNAH14 ARFGEF3 STOX2 PTPN13 KIAA1217 COBL

9.19e-071921748499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 PPP1R9A NCKAP5 RALGAPA2 HMCN1 HECW2 KIAA1217 NAV3

9.56e-071931748e1d546165dcc2392f540162206852c4717d7306f
ToppCellLA|World / Chamber and Cluster_Paper

EHBP1 PCSK5 KCTD8 PCNX2 SLIT2 FBLN1 FBN1 HMCN2

9.56e-071931748d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

FAT4 TCF21 SLIT2 FBLN1 FBN1 DST HMCN1 KAZN

9.56e-071931748acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO5B PPP1R9A DNAH14 ARFGEF3 STOX2 PTPN13 KIAA1217 COBL

9.56e-071931748a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAH14 FBN1 HMCN2 HMCN1 ASXL3 LRP4 UNC80 CALN1

1.03e-061951748d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO5B LAMA5 SPOCK2 NCKAP5 DST COBL ARHGEF26 PLXNA1

1.03e-06195174807a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAH14 FBN1 HMCN2 HMCN1 ASXL3 LRP4 UNC80 CALN1

1.03e-06195174819853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

TCF21 RFTN2 SLIT2 FBLN1 FBN1 DST HMCN1 NAV3

1.03e-06195174861c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

PARD3B SLIT2 FBLN1 FBN1 DST HMCN1 NAV3 KAZN

1.03e-061951748603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO5B LAMA5 SPOCK2 NCKAP5 DST COBL ARHGEF26 PLXNA1

1.03e-061951748b65511770ed67f7447847e2187555b362988af45
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1A USP9X DST NRXN1 UNC80 PCM1 GOLGB1

1.03e-0619517483e519cffa6144a62b06124642a14c9ff39b76554
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MYO5B LAMA5 SPOCK2 NCKAP5 DST COBL ARHGEF26 PLXNA1

1.07e-061961748150554fa06868d29b0608189862eef6505ba757f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 FAT4 TCF21 HECW1 FBLN1 FBN1 HMCN1 NAV3

1.12e-0619717480dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

KALRN SLIT2 FBLN1 FBN1 DST HMCN1 NAV3 KAZN

1.12e-061971748f1c8936986123a3151140c374fcd62d6705c530b
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5B LAMA5 SPOCK2 SLC12A8 NCKAP5 DST COBL ARHGEF26

1.12e-0619717488d5097898dd01cedb04cb694cb480c931e08462c
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CEACAM5 LAMA5 SPOCK2 NCKAP5 MINDY2 DST N4BP1 ARHGEF26

1.12e-0619717489ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 TCF21 PARD3B CBLB SLIT2 DST ASXL3 KAZN

1.12e-06197174811a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 TCF21 COMP HECW1 SLIT2 FBLN1 FBN1 HMCN1

1.16e-061981748300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

LAMA5 SPOCK2 NCKAP5 MINDY2 DST N4BP1 ARHGEF26 PLXNA1

1.16e-061981748fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CEACAM5 LAMA5 SPOCK2 NCKAP5 MINDY2 DST N4BP1 ARHGEF26

1.16e-0619817480047a9ef7684230ac5179efea94461480e90bdaf
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5B PPP1R9A DNAH14 ARFGEF3 STOX2 PTPN13 KIAA1217 COBL

1.20e-0619917485cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellmedial-2-mesenchymal-Myofibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA2 COMP VGLL2 SLIT2 FBLN1 FBN1 HMCN1 ASXL3

1.20e-06199174895aae608fa35a9c82b12c6f18937ce636750ca44
ToppCellmedial-mesenchymal-Myofibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA2 COMP VGLL2 SLIT2 FBLN1 FBN1 HMCN1 ASXL3

1.20e-061991748e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCellmedial-mesenchymal-Myofibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA2 COMP VGLL2 SLIT2 FBLN1 FBN1 HMCN1 ASXL3

1.20e-0619917489ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5B PPP1R9A SLC12A8 RALGAPA2 ARFGEF3 STOX2 KIAA1217 COBL

1.25e-062001748d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CEP85L PPP1R9A ITPRID1 RNF43 ARFGEF3 STOX2 COBL UNC80

1.25e-0620017487c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

PPP1R9A NCKAP5 SHROOM2 DNAH14 DST ZNF660 IL23R

3.68e-0616317477f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

MRC1 RELN KALRN F2RL3 RALGAPA2 FBN1 HECW2

4.31e-06167174797d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 RELN KALRN ZSCAN4 STOX2 FBN1 HECW2

4.85e-0617017476035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 RELN KALRN ZSCAN4 STOX2 FBN1 HECW2

4.85e-061701747c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 RELN KALRN ZSCAN4 STOX2 FBN1 HECW2

4.85e-061701747dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

LAMA5 PARD3B NCKAP5 STOX2 DST COBL ARHGEF26

4.85e-061701747e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 PDE3A COMP SLIT2 FBLN1 FBN1 NAV3

5.04e-0617117475d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

MYO5B SPOCK2 NCKAP5 STOX2 DST COBL ARHGEF26

5.65e-061741747548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PDE3A COMP KALRN CBLB FBN1 HMCN1

6.09e-0617617479bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PDE3A COMP KALRN CBLB FBN1 HMCN1

6.09e-0617617473f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP1R9A FBLN1 STOX2 PTPN13 KIAA1217 COBL ARHGEF26

6.32e-061771747b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5B PPP1R9A LAMA5 PARD3B STOX2 KIAA1217 ARHGEF26

6.80e-061791747cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

KALRN F2RL3 ITPRID1 SHROOM2 HECW2 KIAA1217 TNR

7.06e-061801747b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

EHBP1 RELN PTPN13 NRXN1 KIAA1217 COBL ARHGEF26

7.06e-0618017475842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KIF1A VGLL2 ZNF177 SHROOM2 SLIT2 PTPN13 LRP4

7.32e-06181174747dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KIF1A VGLL2 ZNF177 SHROOM2 SLIT2 PTPN13 LRP4

7.32e-06181174719103221c3a5a16b16378348004b2c50caee4f01
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 COMP FBN1 DST HMCN1 LRP4 ARHGEF26

7.32e-061811747b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF21 SLIT2 FBLN1 THBS4 FBN1 HMCN1 NAV3

7.58e-0618217473dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO5B LAMA5 SPOCK2 NCKAP5 STOX2 COBL ARHGEF26

7.86e-0618317477b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 PCSK5 FAT4 SPOCK2 GJA4 FBN1 ABCA5

7.86e-061831747351d575339038bd4a66f408da518c567444208e8
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CEACAM5 LAMA5 SPOCK2 NCKAP5 DST ARHGEF26 PLXNA1

8.14e-061841747c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CEACAM5 LAMA5 SPOCK2 NCKAP5 DST ARHGEF26 PLXNA1

8.14e-0618417471ed558a88215b248431c524ea16f13d9022ae98c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

MYO5B LAMA5 PARD3B NCKAP5 STOX2 DST ARHGEF26

8.14e-061841747561592edc3083fad41b91811151b442207c65dd9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

MYO5B PARD3B SLC12A8 NCKAP5 DST COBL ARHGEF26

8.44e-06185174732b4e68e551d435a732f253f6ad83408c759a642
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EHBP1 MYO5B PPP1R9A SLC12A8 NCKAP5 STOX2 ALPK2

8.74e-061861747b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PDE3A TCF21 NCKAP5 FBLN1 FBN1 DST UNC80

9.05e-06187174713731298bc562ec29582f5da1b4c97261284f6f1
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

PCSK5 HECW1 NCKAP5 CHORDC1 SLIT2 MALT1 ALPK2

9.05e-061871747acd305475f3609800af0d7bc68d83ef41228080b
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

MYO5B PPP1R9A ARFGEF3 STOX2 PTPN13 KIAA1217 COBL

9.37e-061881747c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1A ARFGEF3 DST NRXN1 UNC80 GOLGB1

9.37e-061881747a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

MYO5B PPP1R9A DNAH14 ARFGEF3 STOX2 PTPN13 COBL

9.37e-061881747707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell3'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCL HECW1 ALPK1 UBOX5 FEZ2 MUC2 AGAP4

9.70e-0618917477dad62bd50c197838058e89abd0ee387de3e83cd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 PDE3A RFTN2 LDLRAD3 RGL1 FBLN1 FBN1

9.70e-061891747c734e5693808a0333139e87bd5be2597a9252afe
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

MYO5B LAMA5 SPOCK2 NCKAP5 DST COBL ARHGEF26

9.70e-0618917475a04cb25f8f0447b2cecdb6c3695029281aca26d
Drugp11-13

USP9X RBMY1A1 RBMY1D RBMY1B RBMY1E PTPN13 MAVS IL3RA

1.13e-07751758CID000015759
Drugbipy

PDE3A DSPP RBMY1A1 RBMY1D RBMY1B RBMY1E BTC SPAG17

8.38e-07971758CID000001474
Drughydantoin-5-propionic acid

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.82e-05211754CID000000782
Drug2-chlorodideoxyadenosine

RBMY1A1 RBMY1D RBMY1B RBMY1E IL3RA

1.92e-05431755CID000072194
Drugchondroitin sulfate

PAPPA2 GCFC2 COMP LAMA5 SPOCK2 ADGRE2 FBLN1 THBS3 THBS4 DST ADAMTS7 NCAN TNR

1.97e-0541317513CID000024766
DrugEtofylline [519-37-9]; Down 200; 17.8uM; PC3; HT_HG-U133A

UBOX5 ZBTB1 BPTF FBLN1 THBS3 PTPN13 NAV3 COBL PLCB3

2.26e-0519717592093_DN
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

MYCL RELN CEACAM5 KIF1A DSPP SLC12A8 ALPK1 SLIT2 FBLN1

2.26e-0519717593639_DN
DrugAZFd

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.66e-05231754CID000196489
Diseasecerebral palsy (implicated_via_orthology)

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.43e-09101695DOID:1969 (implicated_via_orthology)
Diseasebody weight

PAPPA2 EHBP1 PCSK5 RELN C6orf89 DSPP RIPK2 PARD3B CRTAC1 DNAH14 SLIT2 BPTF NRXN1 FEZ2 ASXL3 KIAA1217 SLIT1 ELAVL2 KAZN ARHGEF26 PLXNA1 CALN1 PCM1

9.51e-07126116923EFO_0004338
Diseaseage at onset, multiple sclerosis

PCSK5 RELN NCKAP5

2.15e-05101693EFO_0004847, MONDO_0005301
Diseaseattempted suicide

PCSK5 CNST FAM114A2 FBN1 ABCA5 NAV3 KAZN

7.83e-051781697EFO_0004321
Diseaseintraocular pressure measurement

PCSK5 RELN KALRN C6orf89 PARD3B STOX2 THBS4 NPHP3 FBN1 FEZ2 LRP4

1.81e-0450916911EFO_0004695
Diseasestroke, coronary artery disease

TCF21 C6orf89 ADAMTS7

2.28e-04211693EFO_0000712, EFO_0001645
Diseasespontaneous preterm birth

KALRN NCKAP5 SLIT2 KIAA1217 KAZN

2.95e-041011695EFO_0006917
Diseaseschizophrenia, sex interaction measurement

C6orf89 MINDY2 NAV3 KAZN

3.94e-04601694EFO_0008343, MONDO_0005090
Diseasechronotype measurement

RELN GCFC2 TCF20 NAA11 FNBP4 CRTAC1 RFTN2 RGL1 NRXN1 HECW2 NAV3 PDZD8 KAZN CALN1

5.84e-0488216914EFO_0008328
Diseasewellbeing measurement

EHBP1 FAT4 ZSCAN12 NAA11 FNBP4 SPOCK2 ODAD2 UBOX5 BPTF ASXL3 LRP4 ELAVL2

6.75e-0469216912EFO_0007869
Diseasebipolar II disorder

NCAN SLIT1

8.93e-0481692EFO_0009964
Diseasecleft palate (implicated_via_orthology)

PRMT1 GOLGB1

8.93e-0481692DOID:674 (implicated_via_orthology)
Diseasediet measurement

RNF168 TCF20 KCTD8 ALPK1 RALGAPA2 MINDY2 UBOX5 APLF DNAH14 DST HECW2 KIAA1217 NGEF EEA1 CNGB1

1.08e-03104916915EFO_0008111
Diseasevisceral heterotaxy (implicated_via_orthology)

PCSK5 ODAD2 SLIT2

1.24e-03371693DOID:0050545 (implicated_via_orthology)
Diseasecystic kidney disease (implicated_via_orthology)

LAMA5 SLIT2

1.42e-03101692DOID:2975 (implicated_via_orthology)
Diseasecognitive function measurement

EFL1 AFTPH TCF20 KALRN DSPP MAGEB18 PARD3B EDEM3 RGL1 STOX2 NRXN1 KIAA1217 ZNF335 ELAVL2 EEA1 MUC2 TNR CALN1

1.52e-03143416918EFO_0008354
Diseasebrain infarction (implicated_via_orthology)

PARG ADNP

1.73e-03111692DOID:3454 (implicated_via_orthology)
Diseasemean corpuscular hemoglobin concentration

RMND5A KALRN C6orf89 RNF43 THBS3 NPHP3 HECW2 KIAA1217 NCAN PLCB3 ATF4 AGAP7P ZNF654 EPB41 GOLGB1

1.79e-03110516915EFO_0004528
Diseaseosteoarthritis

RELN HECW1 MYO5B CNST KAZN ALPK2

1.81e-032221696MONDO_0005178
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

CRTAC1 BPTF ZNF335 NCAN PLCB3 CALN1

1.90e-032241696EFO_0004530, EFO_0008317
Diseaseamino acid measurement

FAT4 GCFC2 VGLL2 ODAD2 SLIT2 RGL1 SLIT1 NAV3 ELAVL2 COBL MUC2

1.91e-0367816911EFO_0005134
Diseasecortical surface area measurement

TRPM6 RELN PDE3A TUT7 PARD3B CRTAC1 SLC12A8 NCKAP5 FAM117B RFTN2 STOX1 SLIT2 FBN1 ADAMTS7 NAV3 ELAVL2 SPAG17

1.91e-03134516917EFO_0010736
Diseasehypertrophic cardiomyopathy

CEP85L PARD3B NCKAP5 ABCA5

1.96e-03921694EFO_0000538
Diseasestomach carcinoma (is_implicated_in)

CBLB RNF43

2.07e-03121692DOID:5517 (is_implicated_in)
DiseaseFVC change measurement, response to placebo

RELN KIF1A

2.44e-03131692EFO_0008344, EFO_0010339
Diseasedyslexia

CEP85L CRTAC1 RFTN2 NRXN1 CALN1

2.46e-031621695EFO_0005424
DiseaseKartagener syndrome (implicated_via_orthology)

ODAD2 SLIT2

2.84e-03141692DOID:0050144 (implicated_via_orthology)
Diseasebeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement

FAT4 HECW1

2.84e-03141692EFO_0004670, EFO_0006794
Diseaseleprosy

KALRN RIPK2 LACC1 KAZN

2.96e-031031694EFO_0001054
Diseasecognitive inhibition measurement

TRPM6 TCF20 CNST

2.97e-03501693EFO_0007969
Diseasecorneal topography

PKD1L1 THBS4 FBN1 ADAMTS7

3.62e-031091694EFO_0004345
DiseaseSmall cell carcinoma of lung

MYCL SLIT2 ELAVL2

3.70e-03541693C0149925
Diseasesystemic lupus erythematosus, COVID-19

RFTN2 KEAP1 RGL1

4.52e-03581693MONDO_0007915, MONDO_0100096
Diseaseborna disease (biomarker_via_orthology)

PARG ATF4

4.70e-03181692DOID:5154 (biomarker_via_orthology)
Diseaseidiopathic dilated cardiomyopathy

DSPP PARD3B RFTN2

4.97e-03601693EFO_0009094
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

PCSK5 SLIT2

5.23e-03191692DOID:9562 (implicated_via_orthology)
Diseasehippocampal tail volume

ITPRID1 STOX2

5.23e-03191692EFO_0009398
Diseaseunipolar depression, response to bupropion, mood disorder

STOX2 NAV3

5.23e-03191692EFO_0003761, EFO_0004247, EFO_0006326
Diseasediastolic blood pressure, systolic blood pressure

MRC1 EFL1 VGLL2 CBLB RGL1 FBN1 N4BP2 SOCS5 BTRC PCM1

5.43e-0367016910EFO_0006335, EFO_0006336
Diseaseatrial fibrillation

CEP85L VGLL2 CRTAC1 ALPK1 GORAB SLIT1 PCM1

5.70e-033711697EFO_0000275

Protein segments in the cluster

PeptideGeneStartEntry
QEEEDNSCGTLNSTL

ABCA5

1616

Q8WWZ7
DNERSIPNDGTCFQE

AZI2

321

Q9H6S1
PGSQQVSDFEDNTCE

ADNP

976

Q9H2P0
EFDQQQGSVCPSESE

AGAP4

16

Q96P64
QEPQQEESCQTAAEG

EPB41

31

P11171
SLEFDQQQGSVCPSE

AGAP9

156

Q5VTM2
ENCSSAQGDSLQDES

APLF

326

Q8IW19
SPNGPNNTVCEDVDE

ADGRE2

201

Q9UHX3
CSSENPQLSPNLEDD

ALPK2

106

Q86TB3
SVPNIQDDCNGFQDS

AFTPH

541

Q6ULP2
QCIKEEDTPSDNDSG

ATF4

206

P18848
NSNPVEDEDAVALTC

CEACAM5

331

P06731
DNCPTVPNSAQEDSD

COMP

446

P49747
DDEQSAFACNTRQPG

GJA10

46

Q969M2
EENETCSGGNENQEL

EFL1

916

Q7Z2Z2
FQNSSEREDCNNGEP

BTRC

51

Q9Y297
ASLTVDSCSENQEPG

FAT4

4071

Q6V0I7
ENSCRNEGNTSEITP

DSPP

201

Q9NZW4
SCDNEELNSSPGKNS

ARHGEF26

716

Q96DR7
NLTNNIPGCEEEDAS

CCDC144CP

286

Q8IYA2
ESPCVGNLNDSEGLN

CCDC144CP

1141

Q8IYA2
NDQPEDLIQGCSESD

BPTF

1256

Q12830
NEEESLNETSGNCQT

CALN1

201

Q9BXU9
SDPEEQLSENACISE

ASXL3

596

Q9C0F0
NDTGVPCDEAQQPAS

ADAMTS7

971

Q9UKP4
CVNTQTGLPEEDSDQ

ADAMTS7

1596

Q9UKP4
LSEDCTTTEEGNQPG

ALPK1

901

Q96QP1
EFDQQQGSVCPSESE

AGAP6

16

Q5VW22
VSCGQAESSEKPNAE

PRMT1

31

Q99873
EQAVSPKVDDQCGNS

GORAB

331

Q5T7V8
ATNDGNHPSCQETRD

RBMY1A1

216

P0DJD3
ATNDGNHPSCQETRD

RBMY1B

216

A6NDE4
ATNDGNHPSCQETRD

RBMY1C

216

P0DJD4
ATNDGNHPSCQETRD

RBMY1D

216

P0C7P1
ATNDGNHPSCQETRD

RBMY1E

216

A6NEQ0
ATNDGNHPSCQETRD

RBMY1F

216

Q15415
EECPLTSEAQTNDAA

RFTN2

126

Q52LD8
TSPNCEEDGSQSSSE

RGL1

121

Q9NZL6
EHGEQACERDQSQPS

IQCC

211

Q4KMZ1
DQGSAELCGSQEVDQ

HECW2

561

Q9P2P5
QSDGTQESCESPDVL

NDRG3

351

Q9UGV2
ALNCESAPQGNSELE

PARD3B

811

Q8TEW8
CQSDLEDNVSQGSSD

KCTD8

161

Q6ZWB6
NSDEESCESSQEPGS

LDLRAD3

141

Q86YD5
QNEDCGDDDPQSRLE

KAZN

746

Q674X7
PVSCSSNEGASSQDE

MAGEB18

76

Q96M61
QGAESDQAEPIICSS

MAVS

271

Q7Z434
ECTEDELNNLGHPDN

MALT1

316

Q9UDY8
ANSCQSDSSGFLEEP

ITPRID1

416

Q6ZRS4
LESSDLVDQTEGCQP

LATS2

1071

Q9NRM7
GESNLTNGDEPTQCS

MMS19

536

Q96T76
NDTHTPESNGNKCEA

DST

2241

Q03001
RSEEDSGSQSCEQAP

HECW1

896

Q76N89
GPQDSAQFECVVSNE

HMCN2

3821

Q8NDA2
PSDDENSDNSNECVV

MGRN1

266

O60291
NPTENHETTNLNGEC

EDEM3

866

Q9BZQ6
SQDYDQLPSCSDGSQ

CBLB

886

Q13191
LESCSDDDNQGSKSP

GPATCH4

126

Q5T3I0
EEQDASSNDNFSVCP

PCM1

921

Q15154
PADTSCQVDTSCQGD

PCNX2

326

A6NKB5
DALASCDVNGNDLDP

PCSK5

186

Q92824
INSPLQIDDDFCGQD

PLXNA1

396

Q9UIW2
NSCQDSEADEETSPG

PARG

311

Q86W56
PSGEIVSNCEAAADQ

MUC2

4636

Q02817
TPNTSDNEGSDTEVC

PDZD8

971

Q8NEN9
APAPNEEETCENNES

PDE3A

1046

Q14432
LAEQCSADNNGVELP

NAV3

2106

Q8IVL0
ALSLGQDPSNDCNDN

ILDR1

81

Q86SU0
TNSSEESECDDLDPN

KALRN

2441

O60229
GEQDNCEIETSNGLS

LACC1

56

Q8IV20
QELTDPTCDTDSGQC

LAMA5

1536

O15230
EGPSTTCQEDSCSNQ

NRXN1

1081

Q9ULB1
VEECQQSENAPAAGS

RALGAPA2

736

Q2PPJ7
DALAQQLCEQGAPTD

RELN

171

P78509
DGLSCQDINECQESS

HMCN1

5186

Q96RW7
GQVCANDSDTLELPD

F2RL3

51

Q96RI0
GESEAQAGQETCQDT

PLCB3

881

Q01970
NEQDRCATPHGDNAS

FBLN1

86

P23142
PGDSQNNADATDCQI

ODAPH

31

Q17RF5
SAPSNCISEDEGQNH

PAPPA2

1366

Q9BXP8
DVNNESSSEGFICPQ

EEA1

31

Q15075
STPQRFECDQEEGAN

IL3RA

286

P26951
CSEGSEQQDAPDDSQ

ICE1

1116

Q9Y2F5
NCNHQEGTSSDDELP

GCFC2

421

P16383
GFTASPNQDECLDNR

FBN1

2321

P35555
LNAEVQGQQPECDST

CEP97

841

Q8IW35
ISNEGSEESPCSADD

FAM117B

421

Q6P1L5
SEDGGLQESNPCADD

AVL9

246

Q8NBF6
GSDNCSLADEEQTPR

ARFGEF3

631

Q5TH69
QEDCSDQDLAGTPDL

COBL

436

O75128
SSGHDLIQCNQDQPD

FSCN3

401

Q9NQT6
GECSSPDIQNSVEEE

IL23R

556

Q5VWK5
NLTNNIPGCEEEDAS

CCDC144B

336

Q3MJ40
EFDQQQGSVCPSESE

AGAP7P

16

Q5VUJ5
ETCSLLDQGQEPDQS

CEP85L

681

Q5SZL2
DNSFPTGKTTNDCEE

DNAH14

476

Q0VDD8
SDDPGICSNTDSTQA

EHBP1

666

Q8NDI1
INNNCSSPVDSGNTE

ELAVL2

21

Q12926
DGNCEPAKNSESVDQ

FAM114A2

21

Q9NRY5
NNSPDGNTDSSALDC

KEAP1

381

Q14145
SSASDIFCDNENGPN

CRTAC1

251

Q9NQ79
GDEQSDFECNTAQPG

GJA4

46

P35212
NLTNNIPGCEEEDAS

CCDC144A

336

A2RUR9
ESPCVGNLNDSEGLN

CCDC144A

1331

A2RUR9
TNDCEQNESEPIPAN

C6orf89

141

Q6UWU4
CGDPEENCAATTTQS

BTC

46

P35070
VPELCNQSESSGEDF

SLC12A8

556

A0AV02
SENSCLEDSDPSNLG

PKD1L1

386

Q8TDX9
CLPSASDENENQLDG

CNST

31

Q6PJW8
LDQENCNASPEPGAE

FEZ2

21

Q9UHY8
ADVGPSADEVNNNTC

KIF1A

951

Q12756
SGTDQLSCNSEQKPD

PTPN13

181

Q12923
GDASECPQATNAKDS

PPEF2

731

O14830
ATGEPNFANEDENCV

MRC1

886

P22897
PSSCEFNSEEGAENR

MINDY2

186

Q8NBR6
TNAGNEPDLEDEQVC

USP9X

1271

Q93008
ESDCDPGDQPESQQA

UBOX5

231

O94941
EELCQESGLSVDPSQ

RMND5A

136

Q9H871
SGDSSAIPQANCDSE

SOCS5

311

O75159
EKQCVGEDQPSDSDS

TCP11L2

6

Q8N4U5
DPSQEDLCSVVQSGE

FNBP4

381

Q8N3X1
EDQQAFTQGECPSAN

NCKAP5

1386

O14513
QVFDPGESDSDDNCT

NPHP3

206

Q7Z494
DANQTIQDSKPDSCE

RESF1

601

Q9HCM1
PDQDLQEAAAGCISN

ODAD2

1016

Q5T2S8
NAGAEEVHSDPCENN

NCAN

1001

O14594
PERNASCLADSQDNG

NGEF

81

Q8N5V2
CNASDDDNLEPGFIS

RNF43

91

Q68DV7
SPNSECKGEDATDDQ

KIAA1217

1551

Q5T5P2
AEEGQSTPRQADAQC

SHROOM2

956

Q13796
ESNREPSDPSQCDAN

SPAG17

686

Q6Q759
EFDQQQGSVCPSESE

AGAP5

16

A6NIR3
NSGEPNNSGNEDCAE

CLEC4M

356

Q9H2X3
NDTSNFCPGLQAADS

NCAPH

556

Q15003
GQRFDPETNSDDACT

CHORDC1

11

Q9UHD1
DTGCTDEPNEALEAQ

CNGB1

136

Q14028
PNQSDVDNDLVGDSC

THBS4

611

P35443
VDNDLVGDSCDTNQD

THBS4

616

P35443
NAETCNATGPDLEFS

WDR47

691

O94967
NGAAACPLATEQQSD

TEX13D

171

A0A0J9YY54
DGSPNDCESIEDLLN

USPL1

926

Q5W0Q7
QCSGSVQDPINEDQS

UNC80

1701

Q8N2C7
NTAENQPGEHSLECN

ZNF177

111

Q13360
ACSQSDQLNPEPGEN

TRPM6

1601

Q9BX84
QEAQECNASPSSSGS

VGLL2

36

Q8N8G2
ESCSQEEASERGPQE

MYCL

221

P12524
ACQQKNPATEESGSD

NAA11

191

Q9BSU3
ESQEPNLSAESCGLN

STOX1

811

Q6ZVD7
DLAEGCSQDDQTPSQ

STOX2

511

Q9P2F5
PQEESCGSSQLHENS

RIPK2

341

O43353
DNLCSSGLEASAEQE

TNR

76

Q92752
ESEKDNSQCCDPATN

ZNF660

26

Q6AZW8
GNLESDGDCLQAESE

ZNF646

721

O15015
PDIEPNSENNCSSSD

ZNF654

961

Q8IZM8
EGENTQVAEPEACDQ

UQCC2

41

Q9BRT2
ESTEESSNCENGSPQ

TCF21

36

O43680
TCDDGNDDNSCSPLS

SLIT2

711

O94813
DSCTNSEGSSQPEEQ

TCF20

496

Q9UGU0
DNCLLTPNSGQEDAD

THBS3

481

P49746
GNNTGETENEESCLL

RNF168

366

Q8IYW5
CEPSENNLGSENSAF

ZSCAN4

11

Q8NAM6
SSPVQEDAENASCEL

ZBTB1

411

Q9Y2K1
VCTQDDLPSTDESGN

ZSWIM8

696

A7E2V4
KQPGENSDCHRDSSQ

ZNF8

226

P17098
NSEPCAGSSSESDLQ

UBR7

256

Q8N806
NQESYEDGPCTITSN

TRAPPC8

256

Q9Y2L5
EDGPCTITSNKNSDN

TRAPPC8

261

Q9Y2L5
NCSSSPTIEIQENGD

WWP1

151

Q9H0M0
PENSDCIQADVNSDD

TUT7

721

Q5VYS8
EDCQASGNTLDSALE

ZNF711

316

Q9Y462
PGTEDYQLNSECNSD

SLIT1

496

O75093
TDPPDGQQDSECNRN

TXLNG

116

Q9NUQ3
SQSDAENAAPSCPDE

ZNF335

416

Q9H4Z2
PTCDENGVSLTENSD

ZSCAN12

246

O43309
ESNGLNEDILDNPCN

TIPIN

251

Q9BVW5
ETQGQEDNKTGPCSN

nan

91

A6NL46
NQQGDEALDTTKDPC

SPOCK2

76

Q92563
QGQCGEEEDSLDLSS

TTC31

221

Q49AM3
TDQQESCSSTPGLEE

GOLGB1

1251

Q14789
ADNSDEENCENTGSP

LRP4

296

O75096
QAERDGDSCSISPQD

MYO5B

341

Q9ULV0
GSNQNYICNTDPETD

N4BP1

476

O75113
ENNQEDCDLANSGPL

N4BP2

731

Q86UW6
QSTCDAERGNSEQAE

N4BP2

1191

Q86UW6
ASSCGKEVPEDSNNF

PPP1R9A

376

Q9ULJ8