Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3'-5'-RNA exonuclease activity

EXOSC4 XRN2

8.99e-0437242GO:0000175
GeneOntologyMolecularFunctionRNA exonuclease activity, producing 5'-phosphomonoesters

EXOSC4 XRN2

1.05e-0340242GO:0016896
GeneOntologyMolecularFunctionRNA exonuclease activity

EXOSC4 XRN2

1.33e-0345242GO:0004532
GeneOntologyMolecularFunction3'-5' exonuclease activity

EXOSC4 XRN2

2.43e-0361242GO:0008408
GeneOntologyMolecularFunctionexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

EXOSC4 XRN2

2.51e-0362242GO:0016796
GeneOntologyMolecularFunctionexonuclease activity

EXOSC4 XRN2

5.43e-0392242GO:0004527
GeneOntologyCellularComponentapical junction complex

SORBS1 EPPK1 RPGRIP1L CAMSAP3

2.97e-05158244GO:0043296
GeneOntologyCellularComponentzonula adherens

SORBS1 CAMSAP3

3.52e-058242GO:0005915
GeneOntologyCellularComponentcell-cell junction

SORBS1 FHOD1 EPPK1 SCRIB RPGRIP1L CAMSAP3

4.34e-05591246GO:0005911
GeneOntologyCellularComponentcytoplasmic exosome (RNase complex)

EXOSC4 GTPBP1

1.50e-0416242GO:0000177
GeneOntologyCellularComponentexosome (RNase complex)

EXOSC4 GTPBP1

3.43e-0424242GO:0000178
GeneOntologyCellularComponentexoribonuclease complex

EXOSC4 GTPBP1

4.36e-0427242GO:1905354
GeneOntologyCellularComponentanchoring junction

SORBS1 FHOD1 EPPK1 SCRIB RPGRIP1L CAMSAP3

6.65e-04976246GO:0070161
GeneOntologyCellularComponentadherens junction

SORBS1 SCRIB CAMSAP3

1.78e-03212243GO:0005912
MousePhenoabnormal ventral pancreas morphology

COL4A2 RPGRIP1L

1.05e-054192MP:0013867
MousePhenoabnormal ductus venosus valve morphology

COL4A2 RPGRIP1L CAMSAP3

3.77e-0549193MP:0013877
MousePhenoretrolental blood

COL4A2 CAMSAP3

6.27e-059192MP:0014087
MousePhenoabnormal ductus venosus morphology

COL4A2 RPGRIP1L CAMSAP3

6.27e-0558193MP:0013873
MousePhenoabnormal inferior vena cava morphology

COL4A2 RPGRIP1L CAMSAP3

1.01e-0468193MP:0006063
MousePhenoabnormal vena cava morphology

COL4A2 RPGRIP1L CAMSAP3

1.46e-0477193MP:0006062
MousePhenoabnormal oculomotor nerve morphology

COL4A2 RPGRIP1L

1.58e-0414192MP:0001061
MousePhenoabnormal cervical rib

COL4A2 CAMSAP3

2.08e-0416192MP:0008922
MousePhenoabnormal intestine placement

COL4A2 RPGRIP1L

2.64e-0418192MP:0014023
MousePhenothoracoschisis

COL4A2 RPGRIP1L

2.64e-0418192MP:0008923
MousePhenoabnormal optic chiasm morphology

SCRIB RPGRIP1L

3.28e-0420192MP:0009770
MousePhenoheterochrony

COL4A2 RPGRIP1L

4.35e-0423192MP:0014021
MousePhenobicuspid aortic valve

COL4A2 CAMSAP3

5.15e-0425192MP:0010484
MousePhenoabnormal optic stalk morphology

COL4A2 RPGRIP1L

7.44e-0430192MP:0004268
MousePhenoabsent ductus venosus valve

COL4A2 RPGRIP1L

7.95e-0431192MP:0013876
MousePhenoincreased lung adenoma incidence

CBX7 SCRIB

9.01e-0433192MP:0002048
MousePhenoabnormal lung adenoma incidence

CBX7 SCRIB

9.01e-0433192MP:0020190
MousePhenoabnormal pancreas development

COL4A2 RPGRIP1L

1.01e-0335192MP:0003934
MousePhenoabnormal body wall morphology

COL4A2 SCRIB RPGRIP1L

1.05e-03151193MP:0003385
DomainPHD

BAZ2B PHRF1

4.15e-0375242PF00628
DomainZnf_PHD-finger

BAZ2B PHRF1

4.59e-0379242IPR019787
DomainPHD

BAZ2B PHRF1

5.79e-0389242SM00249
DomainZnf_PHD

BAZ2B PHRF1

6.04e-0391242IPR001965
DomainZF_PHD_2

BAZ2B PHRF1

6.57e-0395242PS50016
DomainZF_PHD_1

BAZ2B PHRF1

6.70e-0396242PS01359
DomainZnf_FYVE_PHD

BAZ2B PHRF1

1.52e-02147242IPR011011
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 LOXL3

1.60e-0418152M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 LOXL3

1.60e-0418152MM14882
PathwayREACTOME_MAJOR_PATHWAY_OF_RRNA_PROCESSING_IN_THE_NUCLEOLUS_AND_CYTOSOL

BYSL EXOSC4 XRN2

8.32e-04180153MM15324
PathwayWP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS

COL4A2 TNXB

9.31e-0443152M39565
PathwayREACTOME_RRNA_PROCESSING

BYSL EXOSC4 XRN2

1.21e-03205153M27685
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 LOXL3

1.26e-0350152MM14796
PathwayKEGG_RNA_DEGRADATION

EXOSC4 XRN2

1.75e-0359152M963
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 LOXL3

1.87e-0361152M27103
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A2 TNXB LOXL3

2.34e-03258153MM14572
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A2 TNXB

2.88e-0376152M27219
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 LOXL3

2.88e-0376152MM14573
PathwayREACTOME_METABOLISM_OF_RNA

BYSL SRRM2 EXOSC4 XRN2

3.27e-03612154MM15547
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL4A2 TNXB

3.50e-0384152M7098
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A2 TNXB LOXL3

3.59e-03300153M610
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

COL4A2 TNXB PPP2R2B

3.66e-03302153M39719
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 LOXL3

4.01e-0390152M631
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

COL4A2 TNXB PPP2R2B

4.54e-03326153MM15917
PathwayWP_PI3KAKT_SIGNALING

COL4A2 TNXB PPP2R2B

5.06e-03339153M39736
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SRRM2 PRRC2A XRN2 FHOD1 CDK11B SCRIB PHRF1 CAMSAP3

3.11e-0877424815302935
Pubmed

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.

BYSL SRRM2 PRRC2A XRN2 PHRF1

8.15e-0816224531363146
Pubmed

Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.

BYSL SRRM2 PRRC2A EXOSC4 XRN2 GTPBP1

1.98e-0738424631059266
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

BYSL SRRM2 PRRC2A EXOSC4 XRN2 CDK11B GTPBP1

3.78e-0771324729802200
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

BYSL EXOSC4 XRN2 CDK11B GTPBP1

7.15e-0725124528077445
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

SRRM2 PRRC2A XRN2 CDK11B SCRIB CAMSAP3

9.58e-0750324616964243
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

BYSL PRRC2A EXOSC4 SORBS1 FHOD1 GTPBP1

1.56e-0654724637267103
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SRRM2 XRN2 FHOD1 EPPK1 SCRIB GTPBP1

2.23e-0658224620467437
Pubmed

Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants.

COL4A2 RPGRIP1L

2.74e-06424236438572
Pubmed

A protein interaction framework for human mRNA degradation.

SRRM2 EXOSC4 XRN2 FHOD1 SCRIB

3.49e-0634724515231747
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

SRRM2 PRRC2A SORBS1 CAMSAP3 GTPBP1

3.49e-0634724517114649
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BYSL SRRM2 PRRC2A XRN2 EPPK1 PHRF1

4.32e-0665324622586326
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

SRRM2 PRRC2A EPPK1

9.15e-065924316083285
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

BYSL NEURL4 PRRC2A EXOSC4 XRN2 GTPBP1

1.02e-0575924635915203
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

BYSL EXOSC4 XRN2 FHOD1 EPPK1 SCRIB GTPBP1

1.60e-05125724736526897
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

SRRM2 CBX7 PRRC2A XRN2 GTPBP1

1.78e-0548624530940648
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

RPGRIP1L PHRF1 CAMSAP3

2.29e-058024319389623
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

BYSL PRRC2A XRN2 EPPK1 SCRIB CAMSAP3

2.94e-0591624632203420
Pubmed

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities.

EXOSC4 XRN2

3.00e-051224214527413
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

BYSL PRRC2A EXOSC4 XRN2 CAMSAP3

3.25e-0555124534728620
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

PRRC2A XRN2 SCRIB GTPBP1

3.54e-0527424434244482
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

BYSL SRRM2 BAZ2B PRRC2A XRN2 CDK11B

3.70e-0595424636373674
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

BYSL SRRM2 PRRC2A EXOSC4 XRN2 GTPBP1

4.08e-0597124633306668
Pubmed

Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.

BAZ2B PRRC2A

4.13e-051424228878358
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BAZ2B PHRF1 CAMSAP3

4.88e-0510324310819331
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

SRRM2 EXOSC4 XRN2 CDK11B

6.16e-0531624431665637
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

SRRM2 NEURL4 PRRC2A SCRIB RPGRIP1L CAMSAP3

6.27e-05104924627880917
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

SRRM2 NEURL4 PRRC2A XRN2 EPPK1

6.56e-0563924523443559
Pubmed

Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.

TNXB PRRC2A

6.94e-051824219116923
Pubmed

Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach.

TNXB PRRC2A

6.94e-051824219143821
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

SRRM2 PRRC2A EXOSC4 XRN2 CAMSAP3

7.37e-0565524535819319
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

SRRM2 PRRC2A CAMSAP3

7.50e-0511924335776542
Pubmed

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

TNXB PHRF1

9.51e-052124221408207
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

BYSL PRRC2A EXOSC4 XRN2 GTPBP1

1.01e-0470124530196744
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

SRRM2 SCRIB RPGRIP1L CAMSAP3

1.03e-0436124430344098
Pubmed

Defining the membrane proteome of NK cells.

BYSL PRRC2A XRN2 FHOD1 PHRF1 GTPBP1

1.13e-04116824619946888
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

BYSL SRRM2 PRRC2A EXOSC4 XRN2

1.23e-0473124529298432
Pubmed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

BYSL CBX7 SCRIB

1.46e-0414924325231870
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

BYSL SCRIB GTPBP1

1.80e-0416024331678930
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SRRM2 PRRC2A XRN2 CDK11B EPPK1

1.96e-0480724522681889
Pubmed

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.

BAZ2B CDK11B

2.24e-043224226142281
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

NEURL4 SORBS1 RPGRIP1L CAMSAP3 GTPBP1

2.53e-0485324528718761
Pubmed

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.

SRRM2 PRRC2A CAMSAP3

2.63e-0418224326527279
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

EXOSC4 XRN2 CDK11B RPGRIP1L

2.80e-0446924427634302
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

BYSL PRRC2A EXOSC4 XRN2

3.13e-0448324436912080
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

BYSL SRRM2 PRRC2A EXOSC4 FHOD1 EPPK1

3.21e-04141524628515276
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

BYSL PRRC2A EXOSC4 PHRF1

3.46e-0449624431343991
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

PPP2R2B XRN2 SCRIB GTPBP1

3.52e-0449824436634849
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

BYSL EXOSC4 PPP2R2B DIPK2A CAMSAP3

3.78e-0493124527432908
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

SRRM2 PRRC2A

4.05e-044324234672947
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

SRRM2 XRN2 CDK11B EPPK1 SCRIB

4.13e-0494924536574265
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NEURL4 PRRC2A SORBS1 SCRIB CAMSAP3

4.42e-0496324528671696
Pubmed

GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.

PRRC2A XRN2 CAMSAP3

4.77e-0422324333731348
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SRRM2 PRRC2A SORBS1

5.28e-0423124316452087
Pubmed

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.

CBX7 RPGRIP1L

5.48e-045024224721909
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

NEURL4 FHOD1 EPPK1 RPGRIP1L

5.62e-0456424421565611
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SRRM2 NEURL4 XRN2 EPPK1 SCRIB

5.84e-04102424524711643
Pubmed

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.

SORBS1 CDK11B GTPBP1

6.26e-0424524319521500
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

SRRM2 CDK11B SCRIB

6.34e-0424624315345747
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

XRN2 EPPK1 SCRIB GTPBP1

6.36e-0458324429844126
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

XRN2 SORBS1 CDK11B RPGRIP1L

6.57e-0458824438580884
Pubmed

Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

TNXB PRRC2A

6.63e-045524214656967
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

RPGRIP1L CAMSAP3 GTPBP1

6.72e-0425124329778605
InteractionPYHIN1 interactions

BYSL SRRM2 EXOSC4 XRN2 CDK11B GTPBP1

3.09e-06358246int:PYHIN1
InteractionPNMA2 interactions

BYSL NEURL4 PRRC2A RPGRIP1L CAMSAP3

1.01e-05251245int:PNMA2
InteractionXRN1 interactions

SRRM2 PRRC2A EXOSC4 XRN2 GTPBP1

1.15e-05258245int:XRN1
InteractionNFX1 interactions

BYSL SRRM2 PRRC2A EXOSC4 XRN2 GTPBP1

1.40e-05466246int:NFX1
InteractionKIF1B interactions

BYSL PRRC2A SCRIB GTPBP1

4.87e-05173244int:KIF1B
InteractionFBXL6 interactions

BYSL PRRC2A EXOSC4 SORBS1 FHOD1 GTPBP1

4.93e-05583246int:FBXL6
InteractionDCAF7 interactions

SRRM2 CBX7 XRN2 CDK11B CAMSAP3

6.31e-05368245int:DCAF7
InteractionEPPK1 interactions

SRRM2 PPP2R2B EPPK1 RPGRIP1L

6.87e-05189244int:EPPK1
InteractionAATF interactions

BYSL SRRM2 PRRC2A XRN2 PHRF1

6.98e-05376245int:AATF
InteractionNUP43 interactions

BYSL SRRM2 BAZ2B XRN2 CDK11B PHRF1

7.25e-05625246int:NUP43
InteractionHECTD1 interactions

BYSL NEURL4 PRRC2A EXOSC4 XRN2 RPGRIP1L GTPBP1

1.08e-04984247int:HECTD1
InteractionSNRNP70 interactions

BYSL SRRM2 PRRC2A EXOSC4 XRN2 CDK11B GTPBP1

1.08e-04984247int:SNRNP70
InteractionUSP16 interactions

BYSL NEURL4 XRN2

1.11e-0479243int:USP16
InteractionNEK1 interactions

EXOSC4 SCRIB RPGRIP1L

1.33e-0484243int:NEK1
InteractionIFI16 interactions

BYSL SRRM2 PRRC2A EXOSC4 XRN2 CDK11B

1.51e-04714246int:IFI16
InteractionSIRT7 interactions

BYSL SRRM2 PRRC2A XRN2 EPPK1 PHRF1

1.89e-04744246int:SIRT7
InteractionDHPS interactions

BYSL SRRM2 EXOSC4

2.29e-04101243int:DHPS
InteractionMTREX interactions

SRRM2 EXOSC4 PPP2R2B XRN2

2.42e-04262244int:MTREX
InteractionCEP135 interactions

NEURL4 RPGRIP1L CAMSAP3 GTPBP1

2.79e-04272244int:CEP135
InteractionDXO interactions

EXOSC4 XRN2

2.82e-0421242int:DXO
InteractionVIM interactions

BYSL SRRM2 SORBS1 EPPK1 SCRIB CAMSAP3

2.87e-04804246int:VIM
InteractionHAPSTR1 interactions

BYSL SRRM2 PRRC2A LOXL3 SCRIB CAMSAP3

3.39e-04829246int:HAPSTR1
InteractionCDC5L interactions

SRRM2 XRN2 FHOD1 EPPK1 SCRIB GTPBP1

4.00e-04855246int:CDC5L
InteractionCPLANE1 interactions

XRN2 RPGRIP1L

4.01e-0425242int:CPLANE1
InteractionRBM7 interactions

SRRM2 EXOSC4 PPP2R2B

4.39e-04126243int:RBM7
InteractionDDRGK1 interactions

BYSL SRRM2 EXOSC4 PPP2R2B XRN2 CDK11B GTPBP1

4.69e-041249247int:DDRGK1
InteractionRAB5B interactions

NEURL4 PPP2R2B RPGRIP1L

4.70e-04129243int:RAB5B
InteractionECT2 interactions

BYSL SRRM2 XRN2 EPPK1 SCRIB RPGRIP1L

4.86e-04887246int:ECT2
InteractionMRPS34 interactions

BYSL PRRC2A PPP2R2B XRN2

4.98e-04317244int:MRPS34
InteractionUCHL5 interactions

CBX7 PRRC2A FHOD1 EPPK1

5.10e-04319244int:UCHL5
InteractionGLDC interactions

PRRC2A XRN2 SCRIB GTPBP1

5.22e-04321244int:GLDC
InteractionOBSL1 interactions

BYSL SRRM2 EXOSC4 XRN2 EPPK1 SCRIB

5.32e-04902246int:OBSL1
InteractionZNF286A interactions

BYSL NEURL4

5.79e-0430242int:ZNF286A
InteractionMRPS27 interactions

BYSL PRRC2A PPP2R2B XRN2

5.99e-04333244int:MRPS27
InteractionYWHAZ interactions

PRRC2A SORBS1 FHOD1 CDK11B SCRIB RPGRIP1L CAMSAP3

6.52e-041319247int:YWHAZ
InteractionCPEB1 interactions

PRRC2A XRN2 GTPBP1

6.74e-04146243int:CPEB1
InteractionPARN interactions

BYSL EXOSC4 XRN2

7.01e-04148243int:PARN
InteractionCSNK2A1 interactions

BYSL SRRM2 CBX7 XRN2 CDK11B PHRF1

7.23e-04956246int:CSNK2A1
InteractionCSNK2B interactions

COL4A2 CBX7 BAZ2B CDK11B PHRF1

7.35e-04625245int:CSNK2B
InteractionSNRNP40 interactions

SRRM2 BAZ2B XRN2 CDK11B PHRF1

8.01e-04637245int:SNRNP40
InteractionBRD7 interactions

SRRM2 CBX7 PRRC2A XRN2 GTPBP1

8.01e-04637245int:BRD7
Cytoband8q24.3

EXOSC4 EPPK1 SCRIB

2.83e-051132438q24.3
CytobandEnsembl 112 genes in cytogenetic band chr8q24

EXOSC4 EPPK1 SCRIB

8.23e-04355243chr8q24
Cytoband22q13.1

CBX7 GTPBP1

9.11e-048524222q13.1
CytobandEnsembl 112 genes in cytogenetic band chr6p21

BYSL TNXB PRRC2A

2.23e-03503243chr6p21
Cytoband6p21.3

TNXB PRRC2A

7.53e-032502426p21.3
CytobandEnsembl 112 genes in cytogenetic band chr22q13

CBX7 GTPBP1

1.28e-02330242chr22q13
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

RPGRIP1L PHRF1 CAMSAP3

2.03e-04181123694
GeneFamilyPHD finger proteins

BAZ2B PHRF1

1.57e-039012288
CoexpressionGSE3039_NKT_CELL_VS_B1_BCELL_UP

CBX7 BAZ2B SORBS1 PHRF1

3.04e-05199244M6432
CoexpressionGSE11924_TFH_VS_TH2_CD4_TCELL_UP

SRRM2 BAZ2B NEURL4 SCRIB

3.10e-05200244M3153
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

R3HDM4 TNXB PPP2R2B

6.19e-051442433ba7f8bd6d1c551048403c94693d63e60f7cbbb7
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

CBX7 TNXB SORBS1

9.77e-05168243a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 CFAP299 LOXL3

9.94e-05169243ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.01e-04170243fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.01e-0417024303044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium|TCGA-Endometrium / Sample_Type by Project: Shred V9

CBX7 TNXB SORBS1

1.01e-04170243cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCellTCGA-Endometrium-Solid_Tissue_Normal|TCGA-Endometrium / Sample_Type by Project: Shred V9

CBX7 TNXB SORBS1

1.01e-041702430bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue|TCGA-Endometrium / Sample_Type by Project: Shred V9

CBX7 TNXB SORBS1

1.01e-04170243516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 FHOD1 DIPK2A

1.16e-0417824393ce73f8bcec63ebf86fabb546f88400e8f06465
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP2R2B XRN2 RPGRIP1L

1.16e-041782430290868dc990878eac5c182fe64968333bc52450
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

COL4A2 SORBS1 EPPK1

1.18e-04179243a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.18e-0417924356db12467b445f2b8ef92af50779eeab10413eb2
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 LOXL3 DIPK2A

1.20e-04180243f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 LOXL3 DIPK2A

1.20e-04180243dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRRM2 BAZ2B XRN2

1.24e-04182243eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRRM2 BAZ2B XRN2

1.26e-0418324328cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRRM2 BAZ2B XRN2

1.26e-041832433fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A2 LOXL3 DIPK2A

1.28e-0418424323c24ab5786af33d605bc445d06117b9da6c6331
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP299 EPPK1 RPGRIP1L

1.34e-0418724304dba2ed09ee4180830bdf0191921696697ea234
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP299 EPPK1 RPGRIP1L

1.34e-04187243805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellInfluenza_Severe-RBC|World / Disease group and Cell class

R3HDM4 TNXB SORBS1

1.36e-04188243f0438e6a77ee1f0456cb65926685266fff470983
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.36e-04188243a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.38e-04189243ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.41e-04190243951e067d14412db67dc3babcdf61e41717d7b429
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.41e-041902431004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.41e-0419024310b02c62e72bfea9767e3e751011436925da823e
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A2 LOXL3 DIPK2A

1.43e-041912432ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellInfluenza_Severe-RBC|Influenza_Severe / Disease group and Cell class

R3HDM4 TNXB SORBS1

1.45e-04192243f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.45e-04192243158cc5736f154da1cb3186ffbf186eae10483e48
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 TNXB LOXL3

1.45e-04192243beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3 DIPK2A

1.45e-04192243f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCellsevere_influenza-RBC|severe_influenza / disease group, cell group and cell class (v2)

R3HDM4 TNXB SORBS1

1.47e-04193243ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.52e-04195243803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.52e-041952434f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.54e-04196243802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNXB LOXL3 EPPK1

1.54e-041962432029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.54e-041962432b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 TNXB SORBS1

1.54e-04196243fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PPP2R2B SORBS1

1.56e-041972435c88a97e8e23a5cd61885acbe1ef339ae6a1e35a
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PPP2R2B SORBS1

1.56e-04197243f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PPP2R2B SORBS1

1.56e-04197243c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PPP2R2B SORBS1

1.56e-04197243ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PPP2R2B SORBS1

1.59e-04198243c12e7511628db819a52959bb68580e27c00c2e41
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFAP299 CDK11B EPPK1

1.59e-041982431847ce8c344c8a3e50f3cbbf758a38aba69f85b0
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PPP2R2B SORBS1

1.59e-0419824322e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 TNXB SORBS1

1.61e-041992439c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 TNXB SORBS1

1.61e-041992437ed541309808f15d65a9c4b26be2050e077539e6
ToppCellInfluenza-Influenza_Severe-Others-RBC|Influenza_Severe / Disease, condition lineage and cell class

R3HDM4 TNXB SORBS1

1.61e-04199243da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 TNXB SORBS1

1.61e-041992433835452e4848d7f7dd8651c17b746b271ef39688
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 TNXB SORBS1

1.61e-0419924314a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CBX7 TNXB FHOD1

1.63e-04200243f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellInfluenza-Influenza_Severe-Others|Influenza_Severe / Disease, condition lineage and cell class

R3HDM4 TNXB SORBS1

1.63e-042002438909da4f7da3bc469a2becb4cfa5c25012af5845
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CBX7 TNXB FHOD1

1.63e-0420024324e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

PRRC2A SORBS1

1.87e-031202423b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CBX7 SORBS1

2.00e-0312424257f3335f751868a768934c757b06a6378148dc9e
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

TNXB SCRIB

2.16e-031292425e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCellCOVID_vent-Lymphocytic-T_cell-Gamma_Delta_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

CFAP299 CAMSAP3

2.26e-03132242dbc0a332fd8f63ebdcf9716e45d7f46f26509349
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

DIPK2A RPGRIP1L

2.43e-03137242a1e34ebbeda3d5a4f14917282d44fcb4dcbf3133
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPGRIP1L PHRF1

2.54e-03140242af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BAZ2B SORBS1

2.64e-0314324239060dc1d87505a16e2df95140087c731f099570
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

R3HDM4 PPP2R2B

2.68e-0314424238ff324366ad5be626e3657c1e33277fc36ddd4c
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

LOXL3 DIPK2A

2.94e-031512423f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEURL4 SORBS1

2.98e-03152242acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEURL4 SORBS1

2.98e-031522429d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIPK2A SCRIB

3.02e-031532424eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIPK2A SCRIB

3.02e-0315324226b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIPK2A SCRIB

3.02e-031532420f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCellAdult-Immune-dendritic_cell-D122|Adult / Lineage, Cell type, age group and donor

EXOSC4 PPP2R2B

3.06e-0315424264a4686586d08b1e9632dde917b472ac660de2d3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 SORBS1

3.14e-03156242363f1b661048d25895e2b8681c82894c957b29c0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 SORBS1

3.14e-03156242d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TNXB LOXL3

3.18e-03157242f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 SORBS1

3.21e-031582428d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

EXOSC4 SCRIB

3.21e-031582424d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

COL4A2 SORBS1

3.29e-03160242958256e3d3836160763b82bb48f794087918d935
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

CBX7 TNXB

3.29e-03160242d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

CBX7 TNXB

3.29e-031602428a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

CBX7 TNXB

3.29e-03160242c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCellControl|World / Disease group and Cell class

CBX7 PPP2R2B

3.34e-03161242e3e72cda7cc70f06d669f26ccf06d51346d7136f
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

COL4A2 EPPK1

3.34e-0316124247b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 LOXL3

3.34e-0316124282ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 SORBS1

3.38e-031622425f009b231f21861afee9cc0c569082e1135f929c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 SORBS1

3.38e-03162242b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 SORBS1

3.38e-0316224268c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNXB PPP2R2B

3.38e-0316224256f1789e69a6cb29956e46aba92b290847327c1f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 SORBS1

3.38e-03162242735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP2R2B SORBS1

3.42e-03163242e526104a3a574ee860078ce7c049e7fec9443f37
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

EPPK1 CAMSAP3

3.46e-0316424285f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CFAP299 DIPK2A

3.46e-03164242346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

EPPK1 CAMSAP3

3.46e-03164242144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 TNXB

3.50e-03165242f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NEURL4 EPPK1

3.50e-0316524234fd00be2b28716c871ad9fb356de84a299a0c01
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP2R2B SCRIB

3.54e-03166242217e0549f88819d02156ea64e8547b658b1c7aef
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic|TCGA-Mesothelium / Sample_Type by Project: Shred V9

COL4A2 LOXL3

3.58e-031672429062577a4b7902c9a888d706589d1b05221c0fa8
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 SORBS1

3.58e-031672425af9127bae05768a5164d5708a4ad37edca99324
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 GTPBP1

3.62e-03168242c7021748003e5949f7caf7b3291c5bad294948c1
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R2B SORBS1

3.62e-0316824288c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|metastatic_Brain / Location, Cell class and cell subclass

DIPK2A GTPBP1

3.67e-0316924271f6761b9927f352e0ccc221ca373319915f4184
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 TNXB

3.67e-031692420d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 CFAP299

3.67e-03169242c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 DIPK2A

3.71e-031702421f994b690e881106a5d54b3080ccce6260bc3ac5
DrugChrysene-1,4-quinone [100900-16-1]; Down 200; 15.4uM; HL60; HG-U133A

BYSL R3HDM4 BAZ2B EXOSC4 SCRIB

1.55e-061932451773_DN
DrugDipyridamole [58-32-2]; Up 200; 8uM; HL60; HG-U133A

COL4A2 EXOSC4 PPP2R2B GTPBP1

4.12e-051872442017_UP
Drugchlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A

SRRM2 CBX7 BAZ2B PRRC2A

4.75e-051942441217_DN
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; HL60; HG-U133A

BYSL R3HDM4 PRRC2A GTPBP1

4.75e-051942441424_DN
DrugNatamycin [7681-93-8]; Down 200; 6uM; PC3; HT_HG-U133A

CBX7 PRRC2A FHOD1 EPPK1

5.25e-051992445809_DN
DrugIohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A

SRRM2 PRRC2A FHOD1 EPPK1

5.35e-052002443322_UP
Diseasesex interaction measurement, inflammatory bowel disease

TNXB PRRC2A

9.17e-0455242EFO_0003767, EFO_0008343
DiseaseMHC class I polypeptide-related sequence A measurement

TNXB PRRC2A

1.40e-0368242EFO_0008233
Diseasenon-alcoholic fatty liver disease, type 2 diabetes mellitus

CFAP299 PPP2R2B

3.60e-03110242EFO_0003095, MONDO_0005148
DiseaseTakayasu arteritis

PRRC2A PPP2R2B

6.42e-03148242EFO_1001857
Diseasebreast cancer (is_implicated_in)

CBX7 PPP2R2B

6.58e-03150242DOID:1612 (is_implicated_in)
Diseaseautism spectrum disorder

XRN2 SORBS1

7.10e-03156242EFO_0003756

Protein segments in the cluster

PeptideGeneStartEntry
RPEGYNLKDEEGRLR

PPP2R2B

126

Q00005
PGRKRRRKGGDSDYD

BAZ2B

1286

Q9UIF8
GGRVRDYLVRKRVGD

GTPBP1

141

O00178
KEERDRYRGEPGEPG

COL4A2

176

P08572
ERFELGDGRKPGEAR

CDK11B

241

P21127
GPRKGDFTRQEYERR

CAMSAP3

971

Q9P1Y5
YLEDEGRSKARRRGP

R3HDM4

136

Q96D70
GRGEDRRREDPAYTP

R3HDM4

151

Q96D70
GYRVDGRRAGELRKI

EXOSC4

11

Q9NPD3
RKPYEGRVEIQRAGE

LOXL3

51

P58215
RYERVGGGPKRLGRD

RPGRIP1L

91

Q68CZ1
RIPKIRRDDGGGRRD

PHRF1

681

Q9P1Y6
YGEPREGGRRRVVLK

DIPK2A

96

Q8NDZ4
EERDRASGYRKRGPK

CBX7

61

O95931
IEEAPGAGGRRERRK

FHOD1

341

Q9Y613
KRRGRGTGEAEEEYV

BYSL

36

Q13895
GDEAHRRRGEPPREY

NEURL4

1376

Q96JN8
VRGRRGERPDYKGEE

SRRM2

26

Q9UQ35
GERPDYKGEEELRRL

SRRM2

31

Q9UQ35
EAVRRGVVGPELYGR

EPPK1

986

P58107
GSEYEEIPKRRRQRG

PRRC2A

1091

P48634
EDDYSPRERRGGGLR

SCRIB

831

Q14160
VELGYRGTGERVKRE

CFAP299

46

Q6V702
QYERKAERGAGERGP

SORBS1

1126

Q9BX66
RRDDRGGRQGYPREG

XRN2

921

Q9H0D6
YKDRDGRPRAVRVGG

TNXB

1406

P22105
YKDRDGRPQVVRVRG

TNXB

2986

P22105