Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlinoleic acid epoxygenase activity

CYP2C19 CYP2C9 CYP2C18

5.34e-094233GO:0071614
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP2C19 CYP2C9 CYP2C18

4.82e-0714233GO:0008401
GeneOntologyMolecularFunction(R)-limonene 6-monooxygenase activity

CYP2C19 CYP2C9

1.27e-062232GO:0052741
GeneOntologyMolecularFunctionlimonene monooxygenase activity

CYP2C19 CYP2C9

1.27e-062232GO:0019113
GeneOntologyMolecularFunction(S)-limonene 6-monooxygenase activity

CYP2C19 CYP2C9

1.27e-062232GO:0018675
GeneOntologyMolecularFunction(S)-limonene 7-monooxygenase activity

CYP2C19 CYP2C9

1.27e-062232GO:0018676
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP2C19 CYP2C9 CYP2C18

2.66e-0624233GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP2C19 CYP2C9 CYP2C18

3.83e-0627233GO:0008391
GeneOntologyMolecularFunctionarachidonate 11,12-epoxygenase activity

CYP2C19 CYP2C9

7.60e-064232GO:0008405
GeneOntologyMolecularFunctionaromatase activity

CYP2C19 CYP2C9 CYP2C18

8.53e-0635233GO:0070330
GeneOntologyMolecularFunctionfatty acid omega-1 hydroxylase activity

CYP2C19 CYP2C9

1.27e-055232GO:0120502
GeneOntologyMolecularFunctionlong-chain fatty acid omega-1 hydroxylase activity

CYP2C19 CYP2C9

1.27e-055232GO:0120319
GeneOntologyMolecularFunctionarachidonate 14,15-epoxygenase activity

CYP2C19 CYP2C9

1.27e-055232GO:0008404
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP2C19 CYP2C9 CYP2C18

2.38e-0549233GO:0016712
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

CYP2C19 CYP2C9

3.54e-058232GO:0033695
GeneOntologyMolecularFunctioncaffeine oxidase activity

CYP2C19 CYP2C9

3.54e-058232GO:0034875
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP2C19 CYP2C9

6.94e-0511232GO:0101020
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups

CYP2C19 CYP2C9

1.32e-0415232GO:0016725
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH9 HOOK2 MYO18B MAP7D3 MYO10 IFT81 SSNA1

1.69e-041099237GO:0008092
GeneOntologyMolecularFunctionmonooxygenase activity

CYP2C19 CYP2C9 CYP2C18

3.03e-04115233GO:0004497
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH9 MYO18B MYO10

3.27e-04118233GO:0003774
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP2C19 CYP2C9

6.96e-0434232GO:0008395
GeneOntologyMolecularFunctionheme binding

CYP2C19 CYP2C9 CYP2C18

7.11e-04154233GO:0020037
GeneOntologyMolecularFunctionoxygen binding

CYP2C19 CYP2C18

8.25e-0437232GO:0019825
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP2C19 CYP2C9 CYP2C18

8.54e-04164233GO:0046906
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH9 MYO10

8.70e-0438232GO:0000146
GeneOntologyMolecularFunctioniron ion binding

CYP2C19 CYP2C9 CYP2C18

8.84e-04166233GO:0005506
GeneOntologyMolecularFunctiontubulin binding

HOOK2 MAP7D3 IFT81 SSNA1

1.33e-03428234GO:0015631
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP2C19 CYP2C9 CYP2C18

1.39e-03194233GO:0016705
GeneOntologyMolecularFunctionactin filament binding

MYH9 MYO18B MYO10

2.17e-03227233GO:0051015
GeneOntologyMolecularFunctionmicrotubule binding

HOOK2 MAP7D3 SSNA1

5.12e-03308233GO:0008017
GeneOntologyMolecularFunctiontransition metal ion binding

CYP2C19 TCHH CYP2C9 CYP2C18 ZCCHC8

1.02e-021189235GO:0046914
GeneOntologyMolecularFunctionactin binding

MYH9 MYO18B MYO10

1.70e-02479233GO:0003779
GeneOntologyBiologicalProcessepoxygenase P450 pathway

CYP2C19 CYP2C9 CYP2C18

1.38e-0622213GO:0019373
GeneOntologyBiologicalProcesslinoleic acid metabolic process

CYP2C19 CYP2C9 CYP2C18

1.59e-0623213GO:0043651
GeneOntologyBiologicalProcessmonoterpenoid metabolic process

CYP2C19 CYP2C9

1.48e-056212GO:0016098
GeneOntologyBiologicalProcesssupramolecular fiber organization

MYH9 TCHH HOOK2 INA MAP7D3 PPFIA1 SSNA1

2.97e-05957217GO:0097435
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP2C19 CYP2C9 CYP2C18

4.37e-0568213GO:0019369
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

HOOK2 MYO10 IFT81 SSNA1

7.13e-05225214GO:0030705
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP2C19 CYP2C9

8.92e-0514212GO:0097267
GeneOntologyBiologicalProcessterpenoid metabolic process

CYP2C19 CYP2C9 CYP2C18

1.59e-04105213GO:0006721
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP2C19 CYP2C9 CYP2C18

2.61e-04124213GO:0001676
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP2C19 CYP2C9 CYP2C18

2.86e-04128213GO:0033559
GeneOntologyBiologicalProcessxenobiotic metabolic process

CYP2C19 CYP2C9 CYP2C18

3.80e-04141213GO:0006805
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP2C19 CYP2C9 CYP2C18

3.88e-04142213GO:0006690
GeneOntologyBiologicalProcessisoprenoid metabolic process

CYP2C19 CYP2C9 CYP2C18

4.04e-04144213GO:0006720
GeneOntologyBiologicalProcessmicrotubule-based process

MYH9 HOOK2 MAP7D3 IFT81 CEP250 SSNA1

5.01e-041058216GO:0007017
GeneOntologyBiologicalProcessxenobiotic catabolic process

CYP2C19 CYP2C9

6.44e-0437212GO:0042178
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

MYH9 HOOK2 MAP7D3 CEP250 SSNA1

6.53e-04720215GO:0000226
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP2C19 CYP2C9 CYP2C18

7.74e-04180213GO:0120254
GeneOntologyBiologicalProcessintraciliary transport

IFT81 SSNA1

1.32e-0353212GO:0042073
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

CYP2C19 CYP2C9 CYP2C18

1.42e-03222213GO:0071466
GeneOntologyBiologicalProcessactomyosin structure organization

MYH9 MYO18B PPFIA1

1.75e-03239213GO:0031032
GeneOntologyCellularComponentmyosin complex

MYH9 MYO18B MYO10

2.74e-0559213GO:0016459
GeneOntologyCellularComponentmyosin filament

MYH9 MYO18B

2.84e-0425212GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH9 MYO18B

3.58e-0428212GO:0016460
GeneOntologyCellularComponentcentriole

IFT81 CEP250 SSNA1

6.53e-04172213GO:0005814
GeneOntologyCellularComponentciliary basal body

IFT81 CEP250 SSNA1

9.39e-04195213GO:0036064
DomainGOLGA6L

GOLGA6L10 GOLGA6L9 GOLGA6L19 GOLGA6L4

4.42e-116264IPR026737
DomainGolgin_A

GOLGA6L10 GOLGA6L9 GOLGA6L19 GOLGA6L4

8.91e-0918264IPR024858
DomainGOLGA2L5

GOLGA6L10 GOLGA6L9 GOLGA6L19 GOLGA6L4

8.91e-0918264PF15070
DomainMYOSIN_MOTOR

MYH9 MYO18B MYO10

1.96e-0538263PS51456
DomainMyosin_head

MYH9 MYO18B MYO10

1.96e-0538263PF00063
DomainMyosin_head_motor_dom

MYH9 MYO18B MYO10

1.96e-0538263IPR001609
DomainMYSc

MYH9 MYO18B MYO10

1.96e-0538263SM00242
DomainLiprin

PPFIA3 PPFIA1

2.79e-056262IPR029515
DomainCyt_P450_E_grp-I

CYP2C19 CYP2C9 CYP2C18

3.27e-0545263IPR002401
DomainCyt_P450_CS

CYP2C19 CYP2C9 CYP2C18

5.36e-0553263IPR017972
DomainCYTOCHROME_P450

CYP2C19 CYP2C9 CYP2C18

6.67e-0557263PS00086
Domain-

CYP2C19 CYP2C9 CYP2C18

7.02e-05582631.10.630.10
Domainp450

CYP2C19 CYP2C9 CYP2C18

7.02e-0558263PF00067
DomainCyt_P450

CYP2C19 CYP2C9 CYP2C18

7.77e-0560263IPR001128
DomainIQ

MYH9 MYO18B MYO10

1.29e-0471263PF00612
DomainIQ

MYH9 MYO18B MYO10

1.90e-0481263SM00015
DomainIQ_motif_EF-hand-BS

MYH9 MYO18B MYO10

2.60e-0490263IPR000048
DomainIQ

MYH9 MYO18B MYO10

2.86e-0493263PS50096
DomainMyosin-like_IQ_dom

MYH9 MYO18B

3.14e-0419262IPR027401
Domain-

MYH9 MYO18B

3.14e-04192624.10.270.10
DomainSAM_2

PPFIA3 PPFIA1

1.62e-0343262PF07647
DomainSAM_1

PPFIA3 PPFIA1

4.01e-0368262PF00536
DomainP-loop_NTPase

CARD10 MYH9 MYO18B MYO10 SSNA1

5.66e-03848265IPR027417
DomainSAM

PPFIA3 PPFIA1

6.63e-0388262SM00454
DomainSAM_DOMAIN

PPFIA3 PPFIA1

7.68e-0395262PS50105
DomainSAM

PPFIA3 PPFIA1

8.00e-0397262IPR001660
Domain-

PPFIA3 PPFIA1

9.49e-031062621.10.150.50
DomainSAM/pointed

PPFIA3 PPFIA1

1.15e-02117262IPR013761
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP2C19 CYP2C9 CYP2C18

4.33e-0714163MM15842
PathwayREACTOME_XENOBIOTICS

CYP2C19 CYP2C9 CYP2C18

2.10e-0623163M5372
PathwayKEGG_LINOLEIC_ACID_METABOLISM

CYP2C19 CYP2C9 CYP2C18

4.31e-0629163M2920
PathwayREACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET

CYP2C19 CYP2C9

3.37e-058162M27135
PathwayKEGG_ARACHIDONIC_ACID_METABOLISM

CYP2C19 CYP2C9 CYP2C18

3.56e-0558163M5410
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP2C19 CYP2C9

4.33e-059162M27143
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP2C19 CYP2C9 CYP2C18

4.36e-0562163M39653
PathwayKEGG_RETINOL_METABOLISM

CYP2C19 CYP2C9 CYP2C18

4.79e-0564163M9488
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP2C19 CYP2C9 CYP2C18

4.79e-0564163M5650
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

CYP2C19 CYP2C9 CYP2C18

6.27e-0570163M16794
PathwayREACTOME_CYP2E1_REACTIONS

CYP2C19 CYP2C9

6.60e-0511162M27130
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

CYP2C19 CYP2C9 CYP2C18

6.82e-0572163M9257
PathwayWP_OCTADECANOID_FORMATION_FROM_LINOLEIC_ACID

CYP2C19 CYP2C9

7.92e-0512162M48064
PathwayREACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.63e-0417162M93
PathwayREACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.63e-0417162MM14907
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.83e-0418162M27043
PathwayREACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.83e-0418162M13015
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.83e-0418162MM14702
PathwayREACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.83e-0418162MM14703
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP2C19 CYP2C9 CYP2C18

2.04e-04104163M738
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PPFIA3 PPFIA1

2.27e-0420162M27290
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PPFIA3 PPFIA1

2.27e-0420162MM14991
PathwayWP_TAMOXIFEN_METABOLISM

CYP2C19 CYP2C9

2.50e-0421162M39631
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

3.01e-0423162MM14852
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

3.01e-0423162M12627
PathwayWP_ESTROGEN_METABOLISM_WP5276

CYP2C19 CYP2C9

3.29e-0424162M46445
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

3.29e-0424162M630
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

3.29e-0424162MM14834
PathwayREACTOME_XENOBIOTICS

CYP2C19 CYP2C9

3.57e-0425162MM14846
PathwayWP_CANNABINOID_RECEPTOR_SIGNALING

CYP2C19 CYP2C9

4.82e-0429162M39676
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

CYP2C19 CYP2C9

5.51e-0431162M39476
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

CYP2C19 CYP2C9

5.87e-0432162M39567
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

CYP2C19 CYP2C9 CYP2C18

1.06e-03183163M39588
PathwayREACTOME_ASPIRIN_ADME

CYP2C19 CYP2C9

1.11e-0344162M45014
PathwayREACTOME_CILIUM_ASSEMBLY

IFT81 CEP250 SSNA1

1.39e-03201163M27472
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.49e-0351162MM14499
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA3 PPFIA1

1.49e-0351162M4281
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

IFT81 CEP250 SSNA1

1.74e-03217163MM14708
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP2C19 CYP2C9 CYP2C18

1.81e-03220163M10320
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP2C19 CYP2C9

1.99e-0359162M27140
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP2C19 CYP2C9

2.48e-0366162MM14839
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

PPFIA3 PPFIA1

2.56e-0367162MM15327
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

CEP250 SSNA1

2.87e-0371162MM15495
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

CEP250 SSNA1

2.95e-0372162M27749
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

CEP250 SSNA1

3.71e-0381162M748
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

CEP250 SSNA1

4.08e-0385162MM14906
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

IFT81 CEP250 SSNA1

4.23e-03297163M27050
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

PPFIA3 PPFIA1

4.27e-0387162M27617
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

CEP250 SSNA1

4.27e-0387162M27194
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

CEP250 SSNA1

4.56e-0390162MM14979
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

CEP250 SSNA1

5.07e-0395162M6729
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

CEP250 SSNA1

5.18e-0396162MM15207
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

CEP250 SSNA1

5.28e-0397162M27478
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP2C19 CYP2C9

6.16e-03105162MM14842
PathwayREACTOME_DRUG_ADME

CYP2C19 CYP2C9

6.62e-03109162M45012
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

MYH9 MYO10

7.22e-03114162MM14814
PathwayREACTOME_PARASITE_INFECTION

MYH9 MYO10

7.47e-03116162M29843
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

MYH9 MYO10

1.12e-02143162M27107
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP2C19 CYP2C9

1.66e-02176162M27854
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

CEP250 SSNA1

1.80e-02184162MM15145
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

CEP250 SSNA1

2.11e-02200162M864
PathwayREACTOME_MITOTIC_PROMETAPHASE

CEP250 SSNA1

2.15e-02202162MM15362
PathwayREACTOME_MITOTIC_PROMETAPHASE

CEP250 SSNA1

2.19e-02204162M4217
Pubmed

Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities.

CYP2C19 CYP2C9 CYP2C18

3.71e-10326315102943
Pubmed

Cloning and expression of complementary DNAs for multiple members of the human cytochrome PH50IIC subfamily.

CYP2C19 CYP2C9 CYP2C18

3.71e-1032638095407
Pubmed

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily.

CYP2C19 CYP2C9 CYP2C18

1.48e-0942632009263
Pubmed

Genetic variation in the CYP2C monooxygenase enzyme subfamily shows no association with longevity in a German population.

CYP2C19 CYP2C9 CYP2C18

1.48e-09426321798861
Pubmed

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.

CYP2C19 CYP2C9 CYP2C18

1.48e-09426323755828
Pubmed

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.

CYP2C19 CYP2C9 CYP2C18

1.48e-09426319706858
Pubmed

Biochemistry and molecular biology of the human CYP2C subfamily.

CYP2C19 CYP2C9 CYP2C18

1.48e-0942637704034
Pubmed

A genome-wide association study of acenocoumarol maintenance dosage.

CYP2C19 CYP2C9 CYP2C18

7.41e-09626319578179
Pubmed

Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population.

CYP2C19 CYP2C9 CYP2C18

1.34e-071426319290787
Pubmed

Association of warfarin dose with genes involved in its action and metabolism.

CYP2C19 CYP2C9 CYP2C18

2.06e-071626317048007
Pubmed

Molecular genetics of the human cytochrome P450 monooxygenase superfamily.

CYP2C19 CYP2C9 CYP2C18

4.19e-07202639890157
Pubmed

CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.

CYP2C19 CYP2C9

5.37e-07226217504998
Pubmed

CYP2C9, but not CYP2C19, polymorphisms affect the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects.

CYP2C19 CYP2C9

5.37e-07226216198656
Pubmed

Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors.

CYP2C19 CYP2C9

5.37e-07226224519941
Pubmed

Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.

CYP2C19 CYP2C9

5.37e-07226214623888
Pubmed

Cytochrome P450 polymorphisms in patients with Behcet's disease.

CYP2C19 CYP2C9

5.37e-07226217269966
Pubmed

Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.

CYP2C19 CYP2C9

5.37e-07226211950794
Pubmed

[Association between genetic polymorphisms of CYP2C19 and CYP2C9 and phenytoin serum concentration].

CYP2C19 CYP2C9

5.37e-07226215569425
Pubmed

Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to drug-induced idiosyncratic liver injury (DILI).

CYP2C19 CYP2C9

5.37e-07226217279092
Pubmed

Rapid testing of clopidogrel resistance by genotyping of CYP2C19 and CYP2C9 polymorphisms using denaturing on-chip capillary electrophoresis.

CYP2C19 CYP2C9

5.37e-07226222589111
Pubmed

Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin-Induced Cutaneous Adverse Drug Reactions.

CYP2C19 CYP2C9

5.37e-07226232216088
Pubmed

cDNA cloning and sequence of CYP2C29 encoding P-450 MUT-2, a microsomal aldehyde oxygenase.

CYP2C19 CYP2C9

5.37e-0722628130255
Pubmed

Membrane integration of recombinant human P450 forms.

CYP2C19 CYP2C9

5.37e-07226219534586
Pubmed

CYP2C9 and CYP2C19 genetic polymorphisms: frequencies in the south Indian population.

CYP2C19 CYP2C9

5.37e-07226215660966
Pubmed

Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.

CYP2C19 CYP2C9

5.37e-07226218511451
Pubmed

Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy.

CYP2C19 CYP2C9

5.37e-07226218154472
Pubmed

Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data.

CYP2C19 CYP2C9

5.37e-07226227353638
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects.

CYP2C19 CYP2C9

5.37e-07226217298483
Pubmed

Analysis of the Potential Association of Drug-Metabolizing Enzymes CYP2C9*3 and CYP2C19*3 Gene Variations With Type 2 Diabetes: A Case-Control Study.

CYP2C19 CYP2C9

5.37e-07226233115391
Pubmed

Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting.

CYP2C19 CYP2C9

5.37e-07226217562299
Pubmed

Developmental expression of human hepatic CYP2C9 and CYP2C19.

CYP2C19 CYP2C9

5.37e-07226214634042
Pubmed

Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines.

CYP2C9 CYP2C18

5.37e-07226222918969
Pubmed

Prevalence of CYP2C9 and CYP2C19 variants and the impact on clopidogrel efficacy in patients having CYPC19*2 variant.

CYP2C19 CYP2C9

5.37e-07226236960518
Pubmed

Characterization of drug-metabolizing enzymes CYP2C9, CYP2C19 polymorphisms in Tunisian, Kuwaiti and Bahraini populations.

CYP2C19 CYP2C9

5.37e-07226226690534
Pubmed

Inter-phenotypic differences in CYP2C9 and CYP2C19 metabolism: Bayesian meta-regression of human population variability in kinetics and application in chemical risk assessment.

CYP2C19 CYP2C9

5.37e-07226233232775
Pubmed

An association between the rs1799853 and rs1057910 polymorphisms of CYP2C9, the rs4244285 polymorphism of CYP2C19 and the prevalence rates of drug-resistant epilepsy in children.

CYP2C19 CYP2C9

5.37e-07226232567426
Pubmed

CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract.

CYP2C19 CYP2C9

5.37e-07226210908295
Pubmed

Role of CYP2C9 and CYP2C19 polymorphisms in patients with atherosclerosis.

CYP2C19 CYP2C9

5.37e-07226217868191
Pubmed

Impact of CYP2C19 and CYP2C9 gene polymorphisms on sodium valproate plasma concentration in patients with epilepsy.

CYP2C19 CYP2C9

5.37e-07226232868386
Pubmed

CYP2C9 and CYP2C19 Allele and Haplotype Distributions in Four Mestizo Populations from Western Mexico: An Interethnic Comparative Study.

CYP2C19 CYP2C9

5.37e-07226227617498
Pubmed

Covariate-based dose individualization of the cytotoxic drug indisulam to reduce the risk of severe myelosuppression.

CYP2C19 CYP2C9

5.37e-07226219199010
Pubmed

Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P-450 isozyme.

CYP2C19 CYP2C9

5.37e-0722621847130
Pubmed

Influence of the CYP2C9 AND CYP2C19 polymorphisms on phenytoin hydroxylation in healthy individuals from south India.

CYP2C19 CYP2C9

5.37e-07226216873909
Pubmed

Cytochromes P450 catalyze oxidation of alpha,beta-unsaturated aldehydes.

CYP2C19 CYP2C9

5.37e-07226217599801
Pubmed

Few alterations in clinical pathology and histopathology observed in a CYP2C18&19 humanized mice model.

CYP2C19 CYP2C18

5.37e-07226219038035
Pubmed

Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.

CYP2C19 CYP2C9

5.37e-07226217304159
Pubmed

Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans.

CYP2C19 CYP2C18

5.37e-0722628110777
Pubmed

Genetic Polymorphisms of CYP2C9/CYP2C19 in Chronic Obstructive Pulmonary Disease.

CYP2C19 CYP2C9

5.37e-07226232757668
Pubmed

Comparison of the in vitro mutagenicity and metabolism of dimethylnitrosamine and benzo[a]pyrene in tissues from inbred mice treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.

CYP2C19 CYP2C9

5.37e-072262106274
Pubmed

A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies.

CYP2C19 CYP2C9

5.37e-07226219358898
Pubmed

Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms.

CYP2C19 CYP2C9

5.37e-07226215385837
Pubmed

[Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms].

CYP2C19 CYP2C9

5.37e-07226225518510
Pubmed

Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18.

CYP2C9 CYP2C18

5.37e-0722628333835
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on phenytoin-induced neurological toxicity in Indian epileptic patients.

CYP2C19 CYP2C9

5.37e-07226220390258
Pubmed

Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians.

CYP2C19 CYP2C9

5.37e-07226219761366
Pubmed

Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations.

CYP2C19 CYP2C9

5.37e-07226214616425
Pubmed

Genetic polymorphism of CYP2C9 and CYP2C19 in a Bolivian population: an investigative and comparative study.

CYP2C19 CYP2C9

5.37e-07226215776277
Pubmed

Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage.

CYP2C19 CYP2C9

5.37e-07226234438105
Pubmed

Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.

CYP2C19 CYP2C9

5.37e-07226215842554
Pubmed

Effect of cytochrome P450 2C19 and 2C9 amino acid residues 72 and 241 on metabolism of tricyclic antidepressant drugs.

CYP2C19 CYP2C9

5.37e-07226224492587
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.

CYP2C19 CYP2C9

5.37e-07226212496751
Pubmed

Voriconazole metabolism, toxicity, and the effect of cytochrome P450 2C19 genotype.

CYP2C19 CYP2C9

5.37e-07226224403552
Pubmed

Rapid identification of the hepatic cytochrome P450 2C19 activity using a novel and noninvasive [13C]pantoprazole breath test.

CYP2C19 CYP2C9

5.37e-07226219136640
Pubmed

Chromosomal organization of the cytochrome P450-2C gene family in the mouse: a locus associated with constitutive aryl hydrocarbon hydroxylase.

CYP2C19 CYP2C9

5.37e-0722622895926
Pubmed

A Novel CYP2C-Haplotype Associated With Ultrarapid Metabolism of Escitalopram.

CYP2C19 CYP2C18

5.37e-07226233759177
Pubmed

Mouse Cyp2c expression and zonation structure in the liver begins in the early neonatal stage.

CYP2C19 CYP2C9

5.37e-07226235748067
Pubmed

Phase I pharmacokinetic and pharmacogenomic study of E7070 administered once every 21 days.

CYP2C19 CYP2C9

5.37e-07226216232205
Pubmed

Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.

CYP2C19 CYP2C9

5.37e-07226232587777
Pubmed

Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China.

CYP2C19 CYP2C9

5.37e-07226220845310
Pubmed

Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Iranian population.

CYP2C19 CYP2C9

5.37e-07226217201743
Pubmed

CYP2C9 (*2&*3) and CYP2C19 (*2&*3) polymorphisms among children with nonlesional epilepsy: a single-center study.

CYP2C19 CYP2C9

5.37e-07226232683556
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics and pharmacodynamics of gliclazide in healthy Chinese Han volunteers.

CYP2C19 CYP2C9

5.37e-07226220831536
Pubmed

Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients.

CYP2C19 CYP2C9

5.37e-07226215855721
Pubmed

Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid.

CYP2C19 CYP2C9

5.37e-0722629721182
Pubmed

The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide in Chinese subjects.

CYP2C19 CYP2C9

5.37e-07226219847408
Pubmed

Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.

CYP2C19 CYP2C9 CYP2C18

1.49e-063026320529763
Pubmed

Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population.

CYP2C19 CYP2C9

1.61e-06326228687336
Pubmed

Distribution of CYP2C polymorphisms in an Amerindian population of Brazil.

CYP2C19 CYP2C9

1.61e-06326221977947
Pubmed

CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population.

CYP2C19 CYP2C9

1.61e-06326216220110
Pubmed

Variability in human drug metabolizing cytochrome P450 CYP2C9, CYP2C19 and CYP3A5 activities caused by genetic variations in cytochrome P450 oxidoreductase.

CYP2C19 CYP2C9

1.61e-06326231128914
Pubmed

Cytochrome p450 genotyping by multiplexed real-time dna sequencing with pyrosequencing technology.

CYP2C19 CYP2C9

1.61e-06326215090156
Pubmed

Pharmacokinetics of CYP2C9, CYP2C19, and CYP2D6 substrates in healthy Chinese and European subjects.

CYP2C19 CYP2C9

1.61e-06326229181698
Pubmed

Polymorphic drug metabolizing CYP-enzymes--a pathogenic factor in oral lichen planus?

CYP2C19 CYP2C9

1.61e-06326219192051
Pubmed

Genetic contribution of CYP2C9, CYP2C19, and APOE variants in acenocoumarol response.

CYP2C19 CYP2C9

1.61e-06326224222221
Pubmed

Investigation of allele and genotype frequencies of CYP2C9, CYP2C19 and VKORC1 in Iran.

CYP2C19 CYP2C9

1.61e-06326220885015
Pubmed

Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales.

CYP2C19 CYP2C9

1.61e-06326219151603
Pubmed

Association of genetic polymorphisms with warfarin dose requirements in Chinese patients.

CYP2C19 CYP2C9

1.61e-06326223941071
Pubmed

Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations.

CYP2C19 CYP2C9

1.61e-06326220665013
Pubmed

CYP2C29 produces superoxide in response to shear stress.

CYP2C19 CYP2C9

1.61e-06326222708815
Pubmed

Hepatotoxicity of oral and intravenous voriconazole in relation to cytochrome P450 polymorphisms.

CYP2C19 CYP2C9

1.61e-06326217827141
Pubmed

CYP2C9, CYP2C19, and ABCB1 genotype and hospitalization for phenytoin toxicity.

CYP2C19 CYP2C9

1.61e-06326219617466
Pubmed

Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants.

CYP2C19 CYP2C9

1.61e-06326227803446
Pubmed

Pharmacogenetic Testing for Analgesic Adverse Effects: Pediatric Case Series.

CYP2C19 CYP2C9

1.61e-06326225803758
Pubmed

Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.

CYP2C19 CYP2C9

1.61e-06326215177309
Pubmed

Development of cocaine-induced interstitial lung damage in two CYP2C and VKORC1 variant allele carriers.

CYP2C19 CYP2C9

1.61e-06326221766908
Pubmed

Genetic polymorphisms of cytochromes P450: CYP2C9, CYP2C19, and CYP2D6 in Croatian population.

CYP2C19 CYP2C9

1.61e-06326212950145
Pubmed

Genetic and phenotypic frequency distribution of CYP2C9, CYP2C19 and CYP2D6 in over 3200 Han Chinese.

CYP2C19 CYP2C9

1.61e-06326232469422
Pubmed

The impact of genetic polymorphisms and patient characteristics on warfarin dose requirements: a cross-sectional study in Iran.

CYP2C19 CYP2C9

1.61e-06326220637959
Pubmed

The impact of Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes on suicide attempt and suicide risk-a European multicentre study on treatment-resistant major depressive disorder.

CYP2C19 CYP2C9

1.61e-06326223081704
Pubmed

The human CYP2C locus: a prototype for intergenic and exon repetition splicing events.

CYP2C9 CYP2C18

1.61e-06326210704292
InteractionWHAMMP3 interactions

RNF40 HOOK2 INA PPFIA1 IFT81 CEP250

4.61e-09119246int:WHAMMP3
InteractionCYP2C19 interactions

CYP2C19 CYP2C9 CYP2C18

1.48e-085243int:CYP2C19
InteractionCYP2C18 interactions

CYP2C19 CYP2C9 CYP2C18

4.26e-0627243int:CYP2C18
InteractionCYP2C9 interactions

CYP2C19 CYP2C9 CYP2C18 ZCCHC8

6.82e-06105244int:CYP2C9
InteractionCDK18 interactions

HOOK2 GOLGA6L9 NSRP1 PPFIA1

1.64e-05131244int:CDK18
InteractionZFP1 interactions

CARD10 HOOK2 GOLGA6L9

2.04e-0545243int:ZFP1
InteractionCEP95 interactions

CARD10 HOOK2 GOLGA6L9

2.80e-0550243int:CEP95
InteractionHBZ interactions

CARD10 MYH9 GOLGA6L9

3.54e-0554243int:HBZ
InteractionZNF80 interactions

CARD10 GOLGA6L9

7.43e-0511242int:ZNF80
InteractionCCDC187 interactions

CARD10 HOOK2 GOLGA6L9

9.85e-0576243int:CCDC187
InteractionTPGS1 interactions

CYP2C9 PPFIA3 PPFIA1

1.19e-0481243int:TPGS1
InteractionZNF844 interactions

HOOK2 GOLGA6L9

1.23e-0414242int:ZNF844
InteractionZNF32 interactions

CARD10 GOLGA6L9

1.61e-0416242int:ZNF32
InteractionMED4 interactions

RNF40 PPFIA3 MAP7D3 IFT81 SSNA1

1.62e-04450245int:MED4
InteractionFAM167A interactions

CARD10 HOOK2 CEP250

1.97e-0496243int:FAM167A
InteractionRCOR1 interactions

RNF40 MYH9 FAM193A ZCCHC8 PPFIA1

2.51e-04494245int:RCOR1
InteractionCEP250 interactions

MYH9 HOOK2 MAP7D3 CEP250

3.42e-04287244int:CEP250
InteractionTBC1D30 interactions

HOOK2 GOLGA6L9

3.69e-0424242int:TBC1D30
InteractionLENG1 interactions

CARD10 HOOK2 GOLGA6L9

3.71e-04119243int:LENG1
InteractionMIB1 interactions

RNF40 MAP7D3 ZCCHC8 CEP250

3.79e-04295244int:MIB1
InteractionPRPF18 interactions

CARD10 HOOK2 GOLGA6L9

3.80e-04120243int:PRPF18
InteractionBRK1 interactions

RNF40 PPFIA3 PPFIA1

4.19e-04124243int:BRK1
InteractionLCA5 interactions

MAP7D3 IFT81 SSNA1

4.29e-04125243int:LCA5
InteractionZNF250 interactions

CARD10 HOOK2 GOLGA6L9

4.39e-04126243int:ZNF250
InteractionIL16 interactions

CARD10 HOOK2 GOLGA6L9

4.49e-04127243int:IL16
InteractionSYCE1 interactions

RNF40 FAM193A INA

4.49e-04127243int:SYCE1
InteractionZNF587 interactions

CARD10 HOOK2 GOLGA6L9

5.37e-04135243int:ZNF587
InteractionKRT23 interactions

INA CEP250

6.19e-0431242int:KRT23
InteractionZNF329 interactions

CARD10 GOLGA6L9

6.60e-0432242int:ZNF329
InteractionTCEANC interactions

HOOK2 GOLGA6L9 SSNA1

6.61e-04145243int:TCEANC
InteractionKDM1A interactions

CARD10 RNF40 MYH9 FAM193A ZCCHC8 PPFIA1

6.65e-04941246int:KDM1A
InteractionPHF21A interactions

RNF40 FAM193A ZCCHC8 PPFIA1

6.69e-04343244int:PHF21A
InteractionTULP3 interactions

MYO18B PPFIA3 PPFIA1 IFT81

6.91e-04346244int:TULP3
InteractionBCL6B interactions

CARD10 GOLGA6L9

7.02e-0433242int:BCL6B
InteractionFLYWCH1 interactions

HOOK2 GOLGA6L9

7.02e-0433242int:FLYWCH1
InteractionLNX1 interactions

MYH9 HOOK2 PPFIA3 PPFIA1 SSNA1

7.84e-04634245int:LNX1
InteractionPTP4A3 interactions

MYH9 PPFIA3 INA

7.87e-04154243int:PTP4A3
InteractionNIN interactions

INA MAP7D3 IFT81 CEP250

7.94e-04359244int:NIN
InteractionBTNL9 interactions

HOOK2 PPFIA3 PPFIA1

8.17e-04156243int:BTNL9
InteractionFAM161A interactions

HOOK2 GOLGA6L9 PPFIA1

8.17e-04156243int:FAM161A
InteractionODF2 interactions

INA MAP7D3 IFT81

8.48e-04158243int:ODF2
InteractionCCDC116 interactions

CARD10 GOLGA6L9

8.82e-0437242int:CCDC116
InteractionPPFIA2 interactions

PPFIA3 PPFIA1

8.82e-0437242int:PPFIA2
Cytoband10q24

CYP2C19 CYP2C9 CYP2C18

9.23e-073525310q24
Cytoband15q25.2

GOLGA6L10 GOLGA6L9 GOLGA6L4

1.74e-064325315q25.2
CytobandEnsembl 112 genes in cytogenetic band chr15q25

GOLGA6L10 GOLGA6L9 GOLGA6L4

9.03e-05160253chr15q25
CytobandEnsembl 112 genes in cytogenetic band chr10q23

CYP2C19 CYP2C9 CYP2C18

1.62e-04195253chr10q23
Cytoband22q13.1

CARD10 MYH9

9.89e-048525222q13.1
CytobandEnsembl 112 genes in cytogenetic band chr22q12

MYH9 MYO18B

7.24e-03235252chr22q12
GeneFamilyCytochrome P450 family 2

CYP2C19 CYP2C9 CYP2C18

3.66e-06351631001
GeneFamilySterile alpha motif domain containing

PPFIA3 PPFIA1

2.69e-0388162760
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHD1 MYO10

1.40e-02206162682
CoexpressionWENG_POR_DOSAGE

CYP2C19 CYP2C9 CYP2C18

2.69e-0630243MM1199
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

CARD10 CYP2C9 HOOK2 CYP2C18 GPA33

3.30e-06259245M40029
CoexpressionWIEMANN_TELOMERE_SHORTENING_AND_CHRONIC_LIVER_DAMAGE_DN

CYP2C19 CYP2C9

1.20e-056242MM971
CoexpressionBROWNE_HCMV_INFECTION_16HR_UP

RNF40 TCHH INA PPFIA1

4.74e-05223244M11383
CoexpressionDESCARTES_MAIN_FETAL_MUC13_DMBT1_POSITIVE_CELLS

CYP2C19 CYP2C18 GPA33

1.40e-04111243M40139
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP2C19 CYP2C9

1.51e-0420242MM1104
CoexpressionWENG_POR_DOSAGE

CYP2C19 CYP2C18

2.01e-0423242M1634
CoexpressionTUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_DN

CYP2C19 CYP2C9

2.19e-0424242MM708
CoexpressionWENG_POR_TARGETS_GLOBAL_DN

CYP2C19 CYP2C9

2.78e-0427242MM1192
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYH9 HOOK2 MYO18B GPA33

4.19e-061892640a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3-5|TCGA-Thymus / Sample_Type by Project: Shred V9

CYP2C19 CYP2C9 CYP2C18

4.60e-051202639d4e630e1d3b9adf94a1884071bfe46edaa3f0c1
ToppCellLA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYH9 MYO18B GPA33

7.12e-051392639e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCellTCGA-Bile_Duct|World / Sample_Type by Project: Shred V9

CYP2C19 CYP2C9 CYP2C18

7.28e-05140263ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

MYH9 MYO18B GPA33

8.41e-051472638970eb6b82589f39439c61a57d999661ec8342de
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CARD10 CYP2C9 SSNA1

1.38e-041742634d8c4a7d8f4972da68cebe0a79eb1a14ec546121
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

MYH9 MYO18B GPA33

1.58e-04182263287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP2C19 CYP2C9 CYP2C18

1.63e-04184263ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP2C19 CYP2C9 CYP2C18

1.69e-04186263bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INA MAP7D3 IFT81

1.69e-04186263f5468e03321ea2083e223eb0d92c3a9307039569
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP2C19 CYP2C9 CYP2C18

1.71e-041872639042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

MYH9 MYO18B GPA33

1.79e-0419026393c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ComputationalCytochrome P450.

CYP2C19 CYP2C9 CYP2C18

9.75e-0714163MODULE_106
ComputationalNeighborhood of CASP2

CARD10 CYP2C9 GPA33

4.37e-04103163MORF_CASP2
ComputationalGenes in the cancer module 135.

CYP2C19 CYP2C18

6.11e-0425162MODULE_135
Drug4',5-dihydroxydiclofenac

CYP2C19 CYP2C9 CYP2C18

2.05e-086243CID003052567
Drug3'-hydroxydiclofenac

CYP2C19 CYP2C9 CYP2C18

2.05e-086243CID000112230
DrugAcenocoumarol

CYP2C19 CYP2C9 CYP2C18

8.61e-089243ctd:D000074
Drug4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide

CYP2C19 CYP2C9 CYP2C18

8.61e-089243ctd:C545880
Drug5-hydroxydiclofenac

CYP2C19 CYP2C9 CYP2C18

2.25e-0712243CID003052566
Drug2'-(glutathion-S-yl)-deschlorodiclofenac

CYP2C19 CYP2C9 CYP2C18

4.64e-0715243ctd:C586542
Drug1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane

CYP2C19 CYP2C9 CYP2C18

5.71e-0716243ctd:C495657
DrugAzamulinum

CYP2C19 CYP2C9 CYP2C18

8.31e-0718243CID003086060
DrugD 703

CYP2C19 CYP2C9 CYP2C18

8.31e-0718243CID000054088
Drughydroxytolbutamide

CYP2C19 CYP2C9 CYP2C18

9.86e-0719243CID000003656
Drugdibenzylfluorescein

CYP2C19 CYP2C9

1.06e-062242ctd:C558664
Drug3C etc

CYP2C19 CYP2C9 CYP2C18

1.16e-0620243CID000164045
DrugTolbutamide

CYP2C19 CYP2C9 CYP2C18

2.33e-0625243ctd:D014044
Drug1,4-naphthoquinone

CYP2C19 CYP2C9 CYP2C18

2.63e-0626243ctd:C035342
Drugpicoxystrobin

CYP2C19 CYP2C9

3.19e-063242ctd:C556557
Drug2-hydroxychlorpropamide

CYP2C19 CYP2C9

3.19e-063242CID003082454
Drugmono-N-demethyladinazolam

CYP2C19 CYP2C9

3.19e-063242ctd:C050132
DrugDelavirdine

CYP2C19 CYP2C9

3.19e-063242ctd:D020008
Drug(hydrochloride)

CYP2C19 CYP2C9 CYP2C18

3.69e-0629243CID000004923
Drugtofisopam

CYP2C19 CYP2C9 CYP2C18

3.69e-0629243CID000005502
Drugtriphenylstannanylium

CYP2C19 CYP2C9 CYP2C18

3.69e-0629243CID000091481
DrugBP-7,8-oxide

CYP2C19 CYP2C9 CYP2C18

5.00e-0632243CID000037455
Drug1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea

CYP2C19 CYP2C9

6.38e-064242ctd:C558737
Drug7,8-dihydromethysticin

CYP2C19 CYP2C9

6.38e-064242ctd:C107882
Drugrabeprazole-thioether

CYP2C19 CYP2C9

6.38e-064242ctd:C523099
Drugmethysticin

CYP2C19 CYP2C9

6.38e-064242ctd:C076881
Drugbenfuracarb

CYP2C19 CYP2C9

1.06e-055242ctd:C096128
Drugbufuralol

CYP2C19 CYP2C9

1.06e-055242ctd:C010831
Drug2-oxo-clopidogrel

CYP2C19 CYP2C9

1.06e-055242ctd:C540904
Drugmono(2-ethyl-5-hydroxyhexyl) phthalate

CYP2C19 CYP2C9

1.06e-055242ctd:C479069
Drugfurafylline

CYP2C19 CYP2C9 CYP2C18

1.07e-0541243CID000003433
Drugsulfaphenazole

CYP2C19 CYP2C9 CYP2C18

1.32e-0544243CID000005335
Drugpolybrominated biphenyl

CYP2C19 CYP2C9 CYP2C18

1.32e-0544243CID000042948
Drugmono(2-ethyl-5-oxohexyl)phthalate

CYP2C19 CYP2C9

1.59e-056242ctd:C080276
Drug4'-hydroxyflurbiprofen

CYP2C19 CYP2C9

1.59e-056242CID000157678
DrugAC1O5Z5L

CYP2C19 CYP2C9

1.59e-056242CID006443527
Drugmepirodipine

CYP2C19 CYP2C9

1.59e-056242ctd:C050699
Drug4,4'-cyclohexylidenebisphenol

CYP2C19 CYP2C9

1.59e-056242ctd:C570106
Drugmono-OH

CYP2C9 CYP2C18

1.59e-056242CID000183679
DrugCyclodextrins

CYP2C19 CYP2C9

1.59e-056242ctd:D003505
Drugavasimibe

CYP2C19 CYP2C9

1.59e-056242ctd:C423185
Drug19-HETE

CYP2C19 CYP2C9 CYP2C18

1.84e-0549243CID006439528
Drug6-hydroxymelatonin

CYP2C19 CYP2C9 CYP2C18

1.95e-0550243CID000001864
Drugformycin triphosphate

MYH9 MYO18B MYO10

2.07e-0551243CID000122274
Drugsulprofos

CYP2C19 CYP2C9

2.23e-057242CID000037125
Drugquinidine-N-oxide

CYP2C19 CYP2C9

2.23e-057242CID000050979
Drug5-n-butyl-pyrazolo(1,5-a)pyrimidine

CYP2C19 CYP2C9

2.23e-057242ctd:C547858
Drug5-fluorotryptamine

CYP2C19 CYP2C9

2.23e-057242ctd:C034536
Drug12-hydroxyellipticine

CYP2C19 CYP2C9

2.23e-057242ctd:C517214
Drug6-Fluoro-6-desoxyoxymorphone

CYP2C19 CYP2C9

2.23e-057242CID005486899
Drug16-O-demethylaconitine

CYP2C19 CYP2C9

2.23e-057242ctd:C486136
DrugVoriconazole

CYP2C19 CYP2C9

2.23e-057242ctd:D065819
Drug5-hydroxydiclofenac

CYP2C19 CYP2C18

2.23e-057242ctd:C117715
Drugdesmethyltrimipramine

CYP2C19 CYP2C9

2.23e-057242CID000160632
Drugtriazolam

CYP2C19 CYP2C9 CYP2C18

2.46e-0554243CID000005556
Drugsulforidazine

CYP2C19 CYP2C9

2.97e-058242CID000031765
Drugclobazam

CYP2C19 CYP2C18

2.97e-058242ctd:C012255
Drug13-hydroxyeicosatetraenoic acid

CYP2C19 CYP2C9

2.97e-058242CID006439499
Drugdesmethylmaprotiline

CYP2C19 CYP2C9

2.97e-058242CID000119409
Drug5-fluoro-alpha-methyltryptamine

CYP2C19 CYP2C9

2.97e-058242ctd:C051101
Druggermacrone

CYP2C19 CYP2C9

2.97e-058242ctd:C048393
Drug5-methyltryptamine

CYP2C19 CYP2C9

2.97e-058242ctd:C027552
Drug11 beta-hydroxytestosterone

CYP2C19 CYP2C9

2.97e-058242CID000114920
Drug7-methyltryptamine

CYP2C19 CYP2C9

2.97e-058242ctd:C036696
Drug1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid

CYP2C19 CYP2C9

2.97e-058242ctd:C585955
DrugAC1L4AGK

CYP2C19 CYP2C9

2.97e-058242CID000182186
Drug11-HODE

CYP2C19 CYP2C9

2.97e-058242CID006438497
Drug5-bromotryptamine

CYP2C19 CYP2C9

2.97e-058242ctd:C040997
Drug4-hydroxyalprazolam

CYP2C19 CYP2C9

2.97e-058242CID000182017
Drugpurealin

MYH9 MYO18B MYO10

3.06e-0558243CID006419303
Drugmiconazole

CYP2C19 CYP2C9 CYP2C18

3.22e-0559243CID000004189
DrugLansoprazole

CYP2C19 CYP2C9 CYP2C18

3.56e-0561243ctd:D064747
DrugBP-4,5-oxide

CYP2C19 CYP2C9 CYP2C18

3.56e-0561243CID000037786
Drug5-chlorotryptamine

CYP2C19 CYP2C9

3.82e-059242ctd:C529169
Drug3-(2-(4-(3-chloro-2-methylphenyl)1-piperazinyl)ethyl)5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazol dihydrochloride 3.5 hydrate

CYP2C19 CYP2C9

3.82e-059242ctd:C109602
Drug2-nitroanisole

CYP2C19 CYP2C9

3.82e-059242ctd:C005328
Drug5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid

CYP2C19 CYP2C9

3.82e-059242ctd:C000588958
DrugTryptamines

CYP2C19 CYP2C9

3.82e-059242ctd:D014363
DrugN-desmethylclobazam

CYP2C19 CYP2C18

3.82e-059242CID000089657
Drugphenylcyclopropane

CYP2C19 CYP2C9

3.82e-059242CID000070112
Drugcis-linoleic acid

CYP2C19 CYP2C9

3.82e-059242CID006431005
DrugFluorescein

CYP2C19 CYP2C9

3.82e-059242ctd:D019793
DrugAC1L8U1Y

CYP2C19 CYP2C9

3.82e-059242CID000408120
Drugchlorzoxazone

CYP2C19 CYP2C9 CYP2C18

3.92e-0563243CID000002733
Drugdiazepam

RNF40 CYP2C19 CYP2C9 CYP2C18

4.29e-05189244CID000003016
Drugpropoxyphene

CYP2C19 CYP2C9 CYP2C18

4.72e-0567243CID000010100
Drugpiperonyl butoxide

CYP2C19 CYP2C9 CYP2C18

4.72e-0567243CID000005794
DrugMephenytoin

CYP2C19 CYP2C9

4.77e-0510242ctd:D008617
Drugsulconazole

CYP2C19 CYP2C9

4.77e-0510242CID000005318
Drug13-hydroxyellipticine

CYP2C19 CYP2C9

4.77e-0510242ctd:C517215
Drug3-hydroxyflunitrazepam

CYP2C19 CYP2C9

4.77e-0510242CID000128908
DrugAHMA

CYP2C19 CYP2C9

4.77e-0510242CID000216240
DrugS)-3-phenylpiperidine

CYP2C19 CYP2C9

4.77e-0510242CID000101021
DrugCelsior

CYP2C19 CYP2C9

4.77e-0510242ctd:C088453
Drug8-hydroxydaidzein

CYP2C19 CYP2C9

4.77e-0510242CID005466139
DrugMelarsoprol

CYP2C19 CYP2C9

4.77e-0510242ctd:D008549
Drugsitaxsentan

CYP2C19 CYP2C9

4.77e-0510242ctd:C106276
Drugnorketobemidone

CYP2C19 CYP2C9

4.77e-0510242CID000161154
Drug5,6-epoxyeicosatrienoic acid

CYP2C19 CYP2C9 CYP2C18

4.93e-0568243CID000001778
Drugraloxifene hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A

INA MAP7D3 GPA33 PPFIA1

5.14e-05198244202_DN
DiseaseX-21258 measurement

CYP2C19 CYP2C9 CYP2C18

4.14e-103233EFO_0800802
DiseaseX-14473 measurement

CYP2C19 CYP2C18

5.81e-072232EFO_0021370
Diseasecyclo(leu-pro) measurement

CYP2C19 CYP2C18

1.74e-063232EFO_0800676
Diseaseglycine conjugate of C10H14O2 (1) measurement

CYP2C9 CYP2C18

1.22e-057232EFO_0800655
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

CYP2C19 CYP2C18

2.09e-059232EFO_0600040
DiseaseX-11308 measurement

CYP2C19 CYP2C9

3.18e-0511232EFO_0800693
Diseasethymol sulfate measurement

CYP2C19 CYP2C9

3.82e-0512232EFO_0021170
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

CYP2C19 CYP2C9 CYP2C18

4.35e-0588233EFO_0803332
DiseaseS-warfarin to R-warfarin ratio measurement

CYP2C19 CYP2C9 CYP2C18

5.46e-0595233EFO_0803331
Diseasemetabolonic lactone sulfate measurement

CYP2C9 CYP2C18

9.86e-0519232EFO_0800659
Diseaseplatelet reactivity measurement, response to clopidogrel

CYP2C19 CYP2C18

1.46e-0423232EFO_0004985, GO_1903493
Diseaseclopidogrel metabolite measurement

CYP2C19 CYP2C18

3.02e-0433232EFO_0007966
Diseaseresponse to anticoagulant

CYP2C19 CYP2C9

4.68e-0441232GO_0061476
DiseaseKidney Failure, Chronic

MYH9 CYP2C19

6.41e-0448232C0022661
Diseasehair morphology measurement

TCHH ZCCHC8

8.11e-0454232EFO_0007821
Diseaseecosanoids measurement

CYP2C9 CYP2C18

8.42e-0455232EFO_0020044
Diseasechronic obstructive pulmonary disease

MYH9 NSRP1 IFT81 SSNA1

1.82e-03688234EFO_0000341

Protein segments in the cluster

PeptideGeneStartEntry
ERLEQRQACEDELRE

RNF40

61

O75150
LRQCRVIDEQDEEEV

CARD10

51

Q9BWT7
LAEEVQRLRARCEEE

INA

171

Q16352
HLQEEQRRREEEEDE

FAM193A

896

P78312
ADDEIEETRVNCRRE

NSRP1

256

Q9H0G5
EQLRELSREREEEDD

GPA33

286

Q99795
DERLRCAELEREVAE

HOOK2

261

Q96ED9
LCREQLLEREEEIAE

PPFIA3

91

O75145
ERRDQELRRLEEEAC

MYO10

921

Q9HD67
ELNVCREQLLEREEE

PPFIA1

96

Q13136
QEERLREQEERLCEQ

GOLGA6L3

211

A6NEY3
REQEERLCEQEERLR

GOLGA6L3

216

A6NEY3
RLCEQEERLREQEER

GOLGA6L3

221

A6NEY3
EQEERLREQEERLCE

GOLGA6L3

231

A6NEY3
LREQEERLCEQEERL

GOLGA6L3

236

A6NEY3
ERLCEQEERLREHEE

GOLGA6L3

241

A6NEY3
QEERLREHEERLCEQ

GOLGA6L3

246

A6NEY3
EERLCEQEERLREQE

GOLGA6L3

261

A6NEY3
ERLHEQEERLCEQEE

GOLGA6L3

276

A6NEY3
QEERLCEQEERLREQ

GOLGA6L3

281

A6NEY3
RLREQEERLCEQEER

GOLGA6L3

291

A6NEY3
EERLCEQEERLREQE

GOLGA6L3

296

A6NEY3
EQEERLREQEERLCE

GOLGA6L3

301

A6NEY3
LREQEERLCEQEERL

GOLGA6L3

306

A6NEY3
ERLCEQEERLREQEE

GOLGA6L3

311

A6NEY3
QEERLREQEERLCEQ

GOLGA6L3

316

A6NEY3
EERLREQEERLCEQE

GOLGA6L4

226

A6NEF3
EQEERLCEQEERLRE

GOLGA6L4

231

A6NEF3
ERLREHEERLCEQEE

GOLGA6L4

241

A6NEF3
RLCEQEERLREQEER

GOLGA6L4

256

A6NEF3
ERLREQEERLCEQEE

GOLGA6L4

276

A6NEF3
QEERLCEQEERLREQ

GOLGA6L4

281

A6NEF3
RLREQEERLCEQEER

GOLGA6L4

291

A6NEF3
EERLCEQEERLREQE

GOLGA6L4

296

A6NEF3
EQEERLREQEERLCE

GOLGA6L4

301

A6NEF3
ERLREQEERLCEQEE

GOLGA6L9

206

A6NEM1
RLCEQEERLREQEER

GOLGA6L9

221

A6NEM1
EERLREQEERLCEQE

GOLGA6L9

226

A6NEM1
HEQEERLCEQEERLR

GOLGA6L10

216

A6NI86
RLCEQEERLREQEER

GOLGA6L10

221

A6NI86
EERLREQEERLCEQE

GOLGA6L10

226

A6NI86
EQEERLCEQEERLRE

GOLGA6L10

231

A6NI86
LCEQEERLREQEERL

GOLGA6L10

236

A6NI86
ERLREQEERLCEQEE

GOLGA6L10

241

A6NI86
QEERLCEQEERLREQ

GOLGA6L10

246

A6NI86
RLREQEERLCEQEER

GOLGA6L10

256

A6NI86
EERLCEQEERLREQE

GOLGA6L10

261

A6NI86
ERLREQEERLCEQEE

GOLGA6L10

276

A6NI86
RLCEQEERLREQEER

GOLGA6L10

291

A6NI86
EERLREQEERLCEQE

GOLGA6L10

296

A6NI86
HEQEERLCEQEERLR

GOLGA6L19

216

H0YKK7
RLCEQEERLREQEER

GOLGA6L19

221

H0YKK7
EERLREQEERLCEQE

GOLGA6L19

226

H0YKK7
EQEERLCEQEERLRE

GOLGA6L19

231

H0YKK7
LCEQEERLREQEERL

GOLGA6L19

236

H0YKK7
ERLREQEERLCEQEE

GOLGA6L19

241

H0YKK7
QEERLCEQEERLREQ

GOLGA6L19

246

H0YKK7
RLREQEERLCEQEER

GOLGA6L19

256

H0YKK7
EERLCEQEERLREQE

GOLGA6L19

261

H0YKK7
EQEERLREQEERLCE

GOLGA6L19

266

H0YKK7
LREQEERLCEQEERL

GOLGA6L19

271

H0YKK7
ERLCEQEERLREQEE

GOLGA6L19

276

H0YKK7
QEERLREQEERLCEQ

GOLGA6L19

281

H0YKK7
REQEERLCEQEERLR

GOLGA6L19

286

H0YKK7
RLCEQEERLREQEER

GOLGA6L19

291

H0YKK7
EERLREQEERLCEQE

GOLGA6L19

296

H0YKK7
EQEERLCEQEERLRE

GOLGA6L19

301

H0YKK7
LCEQEERLREQEERL

GOLGA6L19

306

H0YKK7
ERLREQEERLCEQEE

GOLGA6L19

311

H0YKK7
EARVEEEEERCQHLQ

MYH9

921

P35579
LEQEVRRLREECLQE

IFT81

546

Q8WYA0
IEDRVQEEARCLVEE

CYP2C19

141

P33261
LDELLVRLEEEQQRC

CEP250

96

Q9BV73
REQREKEEEERQREE

MAP7D3

611

Q8IWC1
IEDRVQEEARCLVEE

CYP2C18

141

P33260
IEDRVQEEARCLVEE

CYP2C9

141

P11712
REELCRQIQEEEDEK

SSNA1

26

O43805
DAELRERLRQCEETI

ZCCHC8

46

Q6NZY4
ELCLQREQREELERL

PLEKHD1

176

A6NEE1
REDQEEELEDVRQSC

MYO18B

1736

Q8IUG5
RERQCREEEELQQEE

TCHH

1106

Q07283