Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L21 USP17L23 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

3.16e-1811419819GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L21 USP17L23 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.64e-1712419819GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L21 USP17L23 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.13e-1613719819GO:0019783
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L21 USP17L23 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

6.31e-1419219819GO:0008234
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP32 MYO9B ARHGAP31 TBC1D3I TBC1D3G RASAL2 ACAP3 TBC1D3K TBC1D3F DOCK3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D SIPA1 TBC1D3C TBC1D3B

3.86e-1027919818GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ARHGAP32 MYO9B FRMD7 ARHGEF17 PLEKHG1 ARHGAP31 TBC1D3I TBC1D3G RASAL2 ACAP3 TBC1D3K TBC1D3F DOCK3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D SIPA1 TBC1D3C TBC1D3B ARFGEF3

7.22e-0950719822GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ARHGAP32 MYO9B FRMD7 ARHGEF17 PLEKHG1 ARHGAP31 TBC1D3I TBC1D3G RASAL2 ACAP3 TBC1D3K TBC1D3F DOCK3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D SIPA1 TBC1D3C TBC1D3B ARFGEF3

7.22e-0950719822GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

EPO ARHGAP32 MYO9B ARHGAP31 TBC1D3I TBC1D3G RASAL2 ACAP3 TBC1D3K TBC1D3F DOCK3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D SIPA1 TBC1D3C TBC1D3B CCND3 VAC14 CBX8

6.45e-0765619822GO:0008047
GeneOntologyMolecularFunctionpeptidase activity

USP17L21 RELN USP17L23 USP17L1 USP17L20 USP17L19 HM13 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.34e-0665419821GO:0008233
GeneOntologyMolecularFunctionenzyme regulator activity

EPO ARHGAP32 MYO9B TPRN FRMD7 ARHGEF17 PPP1R26 PLEKHG1 ARHGAP31 TBC1D3I PZP TBC1D3G RASAL2 ACAP3 TBC1D3K TBC1D3F DOCK3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D APC SIPA1 TBC1D3C TBC1D3B PPP4R4 CCND3 ARFGEF3 VAC14 CBX8

2.64e-05141819831GO:0030234
GeneOntologyMolecularFunctiondystroglycan binding

DAG1 CLASP2 CLASP1

1.98e-04121983GO:0002162
GeneOntologyMolecularFunctionmolecular function activator activity

EPO ARHGAP32 RELN MYO9B ARHGAP31 C1QTNF4 TBC1D3I TBC1D3G RASAL2 ACAP3 TBC1D3K TBC1D3F DOCK3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D SIPA1 TBC1D3C TBC1D3B CCND3 VAC14 POMZP3 CBX8

5.32e-04123319825GO:0140677
GeneOntologyMolecularFunctionactin binding

MYO9B TPRN DAG1 CLASP2 BAIAP2L1 SVIL COBL LIMA1 MYO18A TRIOBP SHROOM2 TNS4 SAMD14

1.03e-0347919813GO:0003779
GeneOntologyMolecularFunctionmicrotubule plus-end binding

CLASP2 CLASP1 APC

1.29e-03221983GO:0051010
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYO9B TPRN KIF1B DAG1 CLASP2 CCDC88B AP1AR BAIAP2L1 SVIL KIF14 COBL TRIM46 NPHS1 LIMA1 CLASP1 MYO18A APC TRIOBP SHROOM2 RMDN3 TNS4 SAMD14

1.37e-03109919822GO:0008092
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.96e-1612519718GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.55e-1514419718GO:0070646
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

7.75e-0910919711GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

MYO9B ITGA6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 USP17L2 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.01e-0724419714GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

MYO9B ITGA6 TBC1D3I TBC1D3G PLXNA1 TBC1D3K TBC1D3F PLXNA3 TBC1D3E TBC1D3 USP17L2 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.52e-0733519716GO:0043087
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP17L21 USP17L1 USP17L20 CUL9 USP17L19 MDM2 USP17L18 FBXO22 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 MARCHF7 RFFL USP17L10 RFPL1 HDAC7 MEGF8 USP17L6P USP17L22 USP17L15 RFPL3

1.28e-06100919727GO:0070647
GeneOntologyBiologicalProcesspost-translational protein modification

USP17L21 USP17L1 USP17L20 CUL9 USP17L19 MDM2 USP17L18 FBXO22 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 MARCHF7 RFFL USP17L10 RFPL1 HDAC7 MEGF8 USP17L6P USP17L22 USP17L15 RFPL3

4.13e-06107419727GO:0043687
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

CLASP2 SVIL CLEC16A LIMA1 CLASP1 APC TRIOBP SHROOM2

5.28e-061001978GO:0043242
GeneOntologyBiologicalProcesspositive regulation of basement membrane assembly involved in embryonic body morphogenesis

DAG1 CLASP2 CLASP1

8.46e-0651973GO:1904261
GeneOntologyBiologicalProcessregulation of basement membrane assembly involved in embryonic body morphogenesis

DAG1 CLASP2 CLASP1

8.46e-0651973GO:1904259
GeneOntologyBiologicalProcessbasement membrane assembly involved in embryonic body morphogenesis

DAG1 CLASP2 CLASP1

8.46e-0651973GO:2001197
GeneOntologyBiologicalProcessprotein depolymerization

NCKAP5 CLASP2 SVIL KIF14 LIMA1 CLASP1 APC TRIOBP SHROOM2

1.03e-051441979GO:0051261
GeneOntologyBiologicalProcessregulation of hydrolase activity

MYO9B ITGA6 PPP1R26 NUAK1 TBC1D3I PZP TBC1D3G PLXNA1 TBC1D3K TBC1D3F PLXNA3 TBC1D3E TBC1D3 USP17L2 TBC1D3H TBC1D3L TBC1D3D RFFL RFPL1 TBC1D3C TBC1D3B PPP4R4 CD44

1.18e-0587819723GO:0051336
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

EPO ARHGAP32 RELN MYO9B FRMD7 ARHGEF17 PLEKHG1 HEG1 ARHGAP31 KIF14 DOCK3 SIPA1 ARFGEF3

2.02e-0533319713GO:0051056
GeneOntologyBiologicalProcessnegative regulation of protein depolymerization

CLASP2 SVIL LIMA1 CLASP1 APC TRIOBP SHROOM2

2.32e-05891977GO:1901880
GeneOntologyBiologicalProcessnegative regulation of signal transduction by p53 class mediator

MDM2 BDKRB2 MARCHF7 RFFL CD44

4.28e-05411975GO:1901797
GeneOntologyBiologicalProcessestablishment of cell polarity

MYO9B CLASP2 NSFL1C AMOTL2 WWC1 CYP26B1 CLASP1 MYO18A SIPA1

5.30e-051771979GO:0030010
GeneOntologyBiologicalProcessregulation of protein depolymerization

CLASP2 SVIL LIMA1 CLASP1 APC TRIOBP SHROOM2

6.73e-051051977GO:1901879
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

CLASP2 SVIL CLEC16A LIMA1 CLASP1 APC TRIOBP SHROOM2

7.46e-051441978GO:0043244
GeneOntologyBiologicalProcessregulation of cell adhesion

EPO DAG1 ITGA6 CLASP2 CCDC88B AP1AR AJAP1 NUAK1 GLI2 GLI3 TMEM131L KIF14 PLXNA1 PLXNA3 CLASP1 APC TRIOBP MARCHF7 RUNX1 SIPA1 POMZP3 CD44

8.09e-0592719722GO:0030155
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA1 PLXNA3

9.08e-0521972GO:0021628
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

MYO9B ITGA6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 USP17L2 TBC1D3H TBC1D3L TBC1D3D RFPL1 TBC1D3C TBC1D3B

9.51e-0549919715GO:0051345
GeneOntologyBiologicalProcesscell cycle process

TDRD9 DACH1 CUL9 MCM3 CLASP2 STOX1 PHF8 MDM2 NSFL1C SVIL MKI67 KIF14 DNA2 TOP3B TICRR CYP26B1 USP17L2 CLASP1 AHCTF1 APC XPC MEI1 RFPL1 FOXJ3 CDC14A CCND3 EIF4G1 CENPV CEP131

1.10e-04144119729GO:0022402
GeneOntologyBiologicalProcessregulation of basement membrane organization

DAG1 CLASP2 CLASP1

1.34e-04111973GO:0110011
GeneOntologyBiologicalProcessnegative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

MDM2 BDKRB2 MARCHF7 CD44

1.38e-04281974GO:1902254
GeneOntologyBiologicalProcessbasement membrane assembly

DAG1 CLASP2 CLASP1

1.77e-04121973GO:0070831
GeneOntologyBiologicalProcessregulation of cell cycle process

DACH1 CUL9 STOX1 MDM2 NSFL1C SVIL MKI67 KIF14 DNA2 TICRR USP17L2 AHCTF1 APC XPC RFPL1 CDC14A CCND3 EIF4G1 CENPV CEP131

1.79e-0484519720GO:0010564
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

MYO9B CLASP2 NSFL1C AMOTL2 WWC1 CYP26B1 CLASP1 MYO18A APC SIPA1

1.90e-0425719710GO:0007163
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in ventral spinal cord interneuron specification

GLI2 GLI3

2.71e-0431972GO:0021775
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in spinal cord motor neuron cell fate specification

GLI2 GLI3

2.71e-0431972GO:0021776
GeneOntologyBiologicalProcesssmoothened signaling pathway involved in ventral spinal cord patterning

GLI2 GLI3

2.71e-0431972GO:0021910
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA1 PLXNA3

2.71e-0431972GO:0021627
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix organization

DAG1 CLASP2 CLASP1 RUNX1

2.99e-04341974GO:1903055
GeneOntologyBiologicalProcessneuron development

EPO ARHGAP32 RELN TPRN FRMD7 SCYL1 DAG1 ITGA6 CLASP2 PDZD7 MDM2 UNC5A NRXN3 GLI2 GLI3 MTMR2 COBL PLXNA1 ACAP3 TRIM46 PLXNA3 APC TRIOBP INPP5F RUNX1 MEGF8 CD44 SAMD14

3.34e-04146319728GO:0048666
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

EPO RELN MYO9B ITGA6 STOX1 KIF14 TBC1D3I TBC1D3G TBC1D3K TBC1D3F SPATC1L TBC1D3E TBC1D3 USP17L2 TBC1D3H TBC1D3L TBC1D3D RFPL1 TBC1D3C TBC1D3B CCND3 MST1R

3.47e-04102819722GO:0043085
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix assembly

DAG1 CLASP2 CLASP1

3.59e-04151973GO:1901203
GeneOntologyBiologicalProcessembryonic body morphogenesis

DAG1 CLASP2 CLASP1

3.59e-04151973GO:0010172
GeneOntologyBiologicalProcessproximal/distal pattern formation

GLI2 GLI3 CYP26B1 APC

4.17e-04371974GO:0009954
GeneOntologyBiologicalProcessmicrotubule depolymerization

NCKAP5 CLASP2 KIF14 CLASP1 APC

4.21e-04661975GO:0007019
GeneOntologyBiologicalProcessnegative regulation of DNA damage response, signal transduction by p53 class mediator

MDM2 MARCHF7 CD44

4.38e-04161973GO:0043518
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

EPO ARHGAP32 RELN FRMD7 ITGA6 MDM2 COBL PLXNA1 ACAP3 TRIM46 PLXNA3 TBC1D3 USP17L2 APC MARCHF7 INPP5F MEGF8 CD44 MPHOSPH9

4.99e-0484619719GO:0120035
GeneOntologyBiologicalProcessprotein-containing complex disassembly

NCKAP5 CLASP2 SVIL KIF14 CLEC16A LIMA1 CLASP1 APC TRIOBP SHROOM2

5.09e-0429119710GO:0032984
GeneOntologyBiologicalProcessneuron projection development

EPO ARHGAP32 RELN TPRN FRMD7 DAG1 ITGA6 CLASP2 PDZD7 MDM2 UNC5A NRXN3 GLI2 GLI3 COBL PLXNA1 ACAP3 TRIM46 PLXNA3 APC TRIOBP INPP5F MEGF8 CD44 SAMD14

5.63e-04128519725GO:0031175
GeneOntologyBiologicalProcessnegative regulation of cytoskeleton organization

FRMD7 CLASP2 SVIL LIMA1 CLASP1 APC TRIOBP SHROOM2

5.69e-041941978GO:0051494
GeneOntologyBiologicalProcessnegative regulation of supramolecular fiber organization

FRMD7 CLASP2 SVIL LIMA1 CLASP1 APC TRIOBP SHROOM2

6.30e-041971978GO:1902904
GeneOntologyBiologicalProcessregulation of cell projection organization

EPO ARHGAP32 RELN FRMD7 ITGA6 MDM2 COBL PLXNA1 ACAP3 TRIM46 PLXNA3 TBC1D3 USP17L2 APC MARCHF7 INPP5F MEGF8 CD44 MPHOSPH9

6.35e-0486319719GO:0031344
GeneOntologyBiologicalProcessregulation of actin filament organization

FRMD7 CLASP2 AP1AR BAIAP2L1 SVIL NPHS1 LIMA1 CLASP1 TRIOBP SHROOM2

6.44e-0430019710GO:0110053
GeneOntologyBiologicalProcessnegative regulation of cellular component organization

FRMD7 CLASP2 PHF8 MDM2 SVIL MTMR2 KIF14 CLEC16A TRIM46 PLXNA3 LIMA1 CLASP1 APC TRIOBP MARCHF7 INPP5F SHROOM2 OPRD1 MPHOSPH9

6.44e-0486419719GO:0051129
GeneOntologyBiologicalProcessregulation of intrinsic apoptotic signaling pathway by p53 class mediator

MDM2 BDKRB2 MARCHF7 CD44

6.80e-04421974GO:1902253
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

DAG1 CLASP2 CLASP1 MEGF8 CD44

7.14e-04741975GO:0002011
DomainHABP4_PAI-RBP1

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22

1.62e-211619112PF04774
DomainHABP4_PAIRBP1-bd

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L22

1.62e-211619112IPR006861
DomainUCH

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

4.45e-167119115PF00443
DomainUSP_2

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

4.45e-167119115PS00973
DomainUSP_3

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

5.57e-167219115PS50235
DomainUSP_dom

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

5.57e-167219115IPR028889
DomainPeptidase_C19_UCH

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

5.57e-167219115IPR001394
DomainUSP_CS

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

4.11e-156619114IPR018200
DomainUSP_1

USP17L21 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22

9.91e-157019114PS00972
DomainTBC

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

5.74e-114919110SM00164
DomainRabGAP-TBC

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.32e-105319110PF00566
DomainRab-GTPase-TBC_dom

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.94e-105519110IPR000195
DomainTBC_RABGAP

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.94e-105519110PS50086
DomainARM-type_fold

SCYL1 CUL9 CLASP2 PIK3C2G DOCK3 CLASP1 NOC3L APC MEI1 PPP4R4 ARFGEF3 VAC14 EIF4G1

4.84e-0533919113IPR016024
DomainStorkhead-box_winged-helix

STOX1 STOX2

1.04e-0421912IPR019391
DomainStork_head

STOX1 STOX2

1.04e-0421912PF10264
DomainFHA

KIF1B MKI67 KIF14 CEP170B

1.79e-04281914SM00240
DomainFHA_DOMAIN

KIF1B MKI67 KIF14 CEP170B

2.69e-04311914PS50006
DomainFHA

KIF1B MKI67 KIF14 CEP170B

2.69e-04311914PF00498
DomainRho_GTPase_activation_prot

ARHGAP32 MYO9B ARHGAP31 PLXNA1 RASAL2 PLXNA3

2.86e-04881916IPR008936
DomainPlexin_repeat

PLXNA1 PLXNA3 MST1R MEGF8

3.05e-04321914IPR002165
DomainPSI

PLXNA1 PLXNA3 MST1R MEGF8

3.05e-04321914PF01437
Domain-

KIF1B MKI67 KIF14 CEP170B

4.83e-043619142.60.200.20
DomainFHA_dom

KIF1B MKI67 KIF14 CEP170B

4.83e-04361914IPR000253
DomainDUF21

CNNM2 CNNM4

6.16e-0441912IPR002550
DomainCLASP_N

CLASP2 CLASP1

6.16e-0441912PF12348
DomainCLASP_N_dom

CLASP2 CLASP1

6.16e-0441912IPR024395
DomainDUF21

CNNM2 CNNM4

6.16e-0441912PF01595
DomainHEAT_REPEAT

SCYL1 CLASP2 CLASP1 PPP4R4 VAC14

7.50e-04701915PS50077
DomainRDM_domain_RFPL

RFPL1 RFPL3

1.02e-0351912IPR022723
DomainRDM

RFPL1 RFPL3

1.02e-0351912PF11002
DomainPSI

PLXNA1 PLXNA3 MST1R MEGF8

1.05e-03441914IPR016201
DomainPSI

PLXNA1 PLXNA3 MST1R MEGF8

1.24e-03461914SM00423
PathwayREACTOME_RAS_PROCESSING

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.48e-214513816MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L1 USP17L20 USP17L19 MDM2 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

4.91e-1219113817MM15289
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L1 USP17L20 USP17L19 MDM2 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 APC USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

9.60e-1226213819MM15286
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L1 USP17L20 USP17L19 MDM2 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L22 USP17L15

5.07e-1122113817M27578
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L1 USP17L20 USP17L19 MDM2 USP17L18 USP17L17 USP17L3 VCPIP1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 APC USP17L5 USP17L10 USP17L22 USP17L15

9.50e-1129913819M27574
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 RASAL2 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 CDC14A CCND3 USP17L6P USP17L22 USP17L15

2.72e-1031813819MM15278
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3I TBC1D3G TBC1D3K TBC1D3E TBC1D3 TBC1D3H TBC1D3L RFFL TBC1D3C TBC1D3B

4.32e-089913810M46448
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L21 USP17L1 USP17L20 DAG1 USP17L19 MDM2 USP17L18 PHC3 FBXO22 POM121 USP17L17 USP17L3 VCPIP1 DPH2 SEC16B USP17L4 USP17L2 USP17L12 FBXW9 USP17L11 MUC19 APC MUC16 USP17L5 USP17L10 XPC HDAC7 USP17L6P USP17L22 USP17L15 CBX8

9.06e-06138913831MM15307
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE

PI4K2B MTMR2 INPP5F VAC14

1.10e-05151384MM14643
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE

PI4K2B MTMR2 INPP5F VAC14

1.46e-05161384M639
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L21 USP17L1 USP17L20 DAG1 CUL9 USP17L19 MDM2 USP17L18 PHC3 FBXO22 POM121 USP17L17 USP17L3 VCPIP1 DPH2 SEC16B USP17L4 USP17L2 USP17L12 FBXW9 USP17L11 USP17L24 APC MUC16 USP17L5 USP17L10 XPC HDAC7 USP17L22 USP17L15 CBX8

2.98e-05147513831M19806
PathwayREACTOME_PI_METABOLISM

PI4K2B INPP5D PIK3C2G MTMR2 INPP5F VAC14

1.06e-04771386MM14590
PathwayREACTOME_PI_METABOLISM

PI4K2B INPP5D PIK3C2G MTMR2 INPP5F VAC14

1.72e-04841386M676
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.14e-3221204168622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.14e-32212041614583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.14e-32212041611468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.14e-3221204168756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.14e-32212041612447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.14e-32212041618980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

7.80e-3222204169154835
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

7.61e-3124204168995226
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.10e-30252041621115691
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

5.44e-30262041635816173
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

6.27e-30332041720228807
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041714699124
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041715780755
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041717109758
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041720715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-2934204179806828
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041720403174
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041719188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041711941478
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041720388806
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041720368735
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041710936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.25e-29342041721448158
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.41e-29352041716611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.41e-29352041721239494
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

4.55e-29362041720147298
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

6.84e-29292041632527007
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

8.37e-29372041720228808
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

2.15e-25112041116863688
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

4.46e-24502041631806660
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARHGAP32 KIF1B CLASP2 ARHGEF17 FAM53C FSIP2 PLEKHG1 STOX2 BAIAP2L1 SVIL SIK2 KIF14 COBL RASAL2 VCPIP1 LIMA1 TTC28 CLASP1 APC PTPN21 INPP5F CDC14A HDAC7 PPP4R4 EPN2 ARFGEF3 MEGF8 EIF4G1 CEP131 MPHOSPH9 CEP170B

7.14e-168612043136931259
Pubmed

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

USP17L1 USP17L3 USP17L4 USP17L2 USP17L6P USP17L15

7.79e-1210204624207026
Pubmed

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

USP17L1 USP17L3 USP17L4 USP17L2 USP17L6P USP17L15

3.39e-1112204624695638
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

USP17L1 USP17L3 USP17L4 USP17L2 USP17L6P USP17L15

1.09e-1014204611793228
Pubmed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

USP17L1 USP17L3 USP17L4 USP17L2 USP17L6P USP17L15

9.63e-1019204628067227
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KIF1B CLASP2 PLEKHG1 KIF14 AMOTL2 WWC1 RASAL2 LIMA1 TTC28 CLASP1 APC KIAA1549 INPP5F HDAC7 CEP131 MPHOSPH9 CEP170B

1.47e-094462041724255178
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF1B CUL9 PHF8 ARHGEF17 PLEKHH1 UNC5A PLEKHG1 COBL CLEC16A VCPIP1 TTC28 CLASP1 IGDCC4 ARFGEF3 MEGF8 CEP170B

2.94e-094072041612693553
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

USP17L21 USP17L1 NHSL2 USP17L20 IRF2 USP17L19 USP17L18 USP17L17 USP17L3 DOCK3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 TMEM132D USP17L6P USP17L22 USP17L15

3.73e-096742042037196079
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CLASP2 BAIAP2L1 COBL WWC1 RASAL2 VCPIP1 TTC28 CLASP1 APC ARFGEF3 CEP131 CEP170B

4.59e-092092041236779422
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ARHGAP32 STOX2 POM121 GLI3 SVIL MKI67 TMEM131L RASAL2 VCPIP1 TTC28 AHCTF1 APC KIAA1549

6.29e-092632041334702444
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2B MYO9B CUL9 CLASP2 ANKHD1 PPP1R26 PLEKHG1 HEG1 NUAK1 COBL TOP3B PLXNA1 DOCK3 PLXNA3 DPH2 FBRSL1 HDAC7 CCND3 MST1R VAC14 MEGF8 EIF4G1 CENPV CEP131 CEP170B

9.28e-0911052042535748872
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3G TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3D MYO18A TBC1D3B

1.32e-0874204816625196
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MYO9B TPRN KIF1B BCORL1 CUL9 MCM3 MDM2 BAIAP2L1 TONSL KIF14 VCPIP1 TTC28 CLASP1 FBRSL1 APC ARFGEF3 CEP131 CEP170B

1.45e-085882041838580884
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KMT2B ZC3H13 KIF1B MCM3 PHF8 FAM53C PHC3 NSFL1C SVIL MKI67 VCPIP1 SEC16B LIMA1 CLASP1 MYO18A RFFL XPC RUNX1 HDAC7 EIF4G1

3.70e-087742042015302935
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

USP17L21 USP17L20 USP17L19 USP17L18 NUAK1 USP17L17 USP17L12 PCDHGC4 USP17L11

3.82e-08119204928625976
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

KIF1B SCYL1 MCM3 CLASP2 SNAP47 BAIAP2L1 GLI3 MKI67 CLEC16A RASAL2 TTC28 NOC3L APC MUC16 ABCC5 ARFGEF3 CD44 CEP131 MPHOSPH9

1.92e-077772041935844135
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

ARHGAP32 KIF1B MCM3 PHF8 PLEKHG1 NSFL1C BAIAP2L1 SVIL MTMR2 KIF14 COBL CLEC16A VCPIP1 TTC28 NOC3L APC MPHOSPH9 CEP170B CBX8

7.84e-078532041928718761
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3F TBC1D3 TBC1D3D

7.92e-074204312359748
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3F TBC1D3 TBC1D3D

7.92e-07420438406013
Pubmed

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.

KIF1B CLASP2 FAM53C LIMA1 CLASP1 SHROOM2 HDAC7

8.47e-0787204717979178
Pubmed

Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.

DAG1 ITGA6 GLI2 GLI3

1.10e-0614204419783738
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ARHGAP32 TPRN ITGA6 CLASP2 PHF8 SVIL MKI67 MTMR2 KIF14 TOP3B NOC3L TRIOBP KIAA1549 PTPN21 CDC14A PPP4R4 CNNM4 CD44 CEP131 MPHOSPH9 CBX8

1.12e-0610492042127880917
Pubmed

Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.

MDM2 VCPIP1 TRIM46 MARCHF7

1.49e-0615204429295817
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGAP32 INPP5D SCYL1 MDM2 PHC3 POM121 BAIAP2L1 ARHGAP31 GLI2 TONSL DOCK3 FOXJ3 TSHZ1

1.80e-064302041335044719
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

1.97e-065204312604796
Pubmed

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex.

DAG1 CLASP2 CLASP1

1.97e-065204323940118
Pubmed

Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.

CLASP2 CLASP1 APC

1.97e-065204317113391
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3F TBC1D3 TBC1D3D

1.97e-06520438471161
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PHF8 ANKHD1 MTMR2 TTC28 FOXJ3 EPN2 CEP131

2.83e-06104204710470851
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

KIF1B BAIAP2L1 SVIL RASAL2 LIMA1 CLASP1 SHROOM2 HDAC7 EPN2 RMDN3

2.98e-062552041015324660
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ANKHD1 STOX2 NRXN3 NUAK1 ARHGAP31 TMEM131L AMOTL2 DNA2 ACAP3 FBRSL1 TRIOBP KIAA1549 INPP5F FOXJ3

3.37e-065292041414621295
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ARHGAP32 KIF1B CLASP2 MDH2 ARHGEF17 SNAP47 NDUFV1 SVIL MTMR2 RASAL2 TRIM46 SLC12A6 LIMA1 CLASP1 PRR36 MYO18A APC KIAA1549 SIPA1 GRM2 SHROOM2 EPN2 EIF4G1 CEP170B

4.03e-0614312042437142655
Pubmed

Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog.

GLI2 GLI3 MKI67 TSHZ1

4.16e-0619204432234482
Pubmed

APC sets the Wnt tone necessary for cerebral cortical progenitor development.

GLI2 GLI3 MKI67 APC

4.16e-0619204428916710
Pubmed

Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development.

GLI2 GLI3 MKI67 CD44

4.16e-0619204423645682
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP32 NHSL2 MCM3 CLASP2 STOX2 SVIL TOP3B RASAL2 TRIM46 LIMA1 CLASP1 PRR36 APC TRIOBP SIPA1 GRM2 EIF4G1 CEP131 CEP170B

4.58e-069632041928671696
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ARHGAP32 MYO9B MDM2 MTMR2 PLXNA3 TBC1D3H ZNF652 MUC16 ABCC5 CCND3 ARFGEF3 CD44 TNS4 TINCR

5.48e-065522041410737800
Pubmed

A protein interaction landscape of breast cancer.

DAG1 CUL9 MDM2 NUAK1 SVIL MKI67 AMOTL2 TTC28 NOC3L MYO18A XPC RUNX1 SIPA1 CCND3 CBX8

5.81e-066342041534591612
Pubmed

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.

GLI2 GLI3 MKI67 KRT75

6.36e-0621204422935613
Pubmed

Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.

GLI2 GLI3 MKI67

6.84e-067204328799057
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ARHGAP32 FRMD7 DAG1 ITGA6 AP1AR BAIAP2L1 ARHGAP31 COBL PLXNA1 RASAL2 KIAA1549 ABCC5 EPN2 CD44

7.72e-065692041430639242
Pubmed

Human and mouse proteases: a comparative genomic approach.

USP17L1 USP17L3 USP17L4 USP17L2 USP17L6P USP17L15

8.52e-0681204612838346
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

ZC3H13 ANKHD1 CCDC88B QRICH2 AP1AR SIK2 TMEM131L PLXNA1 TBC1D3F SPATC1L VCPIP1 PDZRN4 LIMA1 TBC1D3 TBC1D3D POLI

1.03e-057502041611230166
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

ARHGAP31 SVIL MKI67 KIF14 RASAL2 VCPIP1 CEP131 CEP170B

1.41e-05184204832908313
Pubmed

Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis.

RELN GLI2 GLI3 MKI67

1.55e-0526204426387942
Pubmed

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.

DACH1 NPHS1 CD44

1.63e-059204335499085
Pubmed

Gli3 null mice display glandular overgrowth of the developing stomach.

GLI2 GLI3 MKI67

1.63e-059204316247775
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ARHGAP32 HM13 PLEKHG1 KIF14 TRIOBP ARFGEF3 CEP131 MPHOSPH9 CEP170B

1.91e-05251204929778605
Pubmed

Novel interactors and a role for supervillin in early cytokinesis.

SVIL KIF14 LIMA1 MPHOSPH9

2.11e-0528204420309963
Pubmed

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

INPP5D CLASP2 KIF14 CLASP1 CEP170B

2.16e-0557204529089450
Pubmed

Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis.

GLI2 GLI3 MKI67

2.31e-0510204338358805
Pubmed

EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.

CLASP2 CLASP1 APC

2.31e-0510204323001180
Pubmed

Direct and indirect requirements of Shh/Gli signaling in early pituitary development.

GLI2 GLI3 MKI67 CD44

2.43e-0529204420934421
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RELN KIF1B CUL9 NCKAP5 FAM53C PLEKHH1 MTMR2 AMOTL2 RASAL2 SPATC1L VCPIP1 DOCK3 TTC28 APC TRIOBP ZNF343 ABCC5 XPC RUNX1 SHROOM2 EIF4G1

2.46e-0512852042135914814
Pubmed

Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells.

GLI2 GLI3 MKI67 CCND3

2.79e-0530204424073291
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CUL9 CLASP2 PPP1R26 POM121 COBL CLASP1

3.19e-0510220469734811
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

KMT2B ZC3H13 BCORL1 STOX1 PHF8 ARHGEF17 QRICH2 IGSF10 USP17L3 AMOTL2 IPPK TICRR CYP26B1 USP17L12 MUC19

3.31e-057362041529676528
Pubmed

A human MAP kinase interactome.

ARHGAP32 NCKAP5 CCDC88B FAM53C POM121 ARHGAP31 COBL TBC1D3F MYO18A APC RMDN3 MPHOSPH9

3.37e-054862041220936779
Pubmed

Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.

CLASP2 CLASP1

3.42e-052204216914514
Pubmed

DACH1 suppresses breast cancer as a negative regulator of CD44.

DACH1 CD44

3.42e-052204228659634
Pubmed

A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.

GLI2 GLI3

3.42e-052204217283082
Pubmed

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

GLI2 GLI3

3.42e-052204220154143
Pubmed

Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis.

MKI67 APC

3.42e-052204233658388
Pubmed

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics.

CLASP2 CLASP1

3.42e-052204212837247
Pubmed

Gene expression profiling revealed MCM3 to be a better marker than Ki67 in prognosis of invasive ductal breast carcinoma patients.

MCM3 MKI67

3.42e-052204231980982
Pubmed

In vitro study on the effect of doxorubicin on the proliferation markers MCM3 and Ki-67.

MCM3 MKI67

3.42e-052204224344040
Pubmed

Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis.

MDM2 APC

3.42e-052204227617574
Pubmed

Dimerization of the CNNM extracellular domain.

CNNM2 CNNM4

3.42e-052204238149326
Pubmed

Mg2+-dependent interactions of ATP with the cystathionine-β-synthase (CBS) domains of a magnesium transporter.

CNNM2 CNNM4

3.42e-052204224706765
Pubmed

Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice.

APC TNS4

3.42e-052204232567731
InteractionYWHAH interactions

ARHGAP32 NHSL2 ZC3H13 KIF1B CLASP2 ARHGEF17 FAM53C PLEKHG1 STOX2 NUAK1 BAIAP2L1 SVIL SIK2 KIF14 COBL AMOTL2 CLEC16A WWC1 RASAL2 VCPIP1 TICRR LIMA1 TTC28 CLASP1 APC PTPN21 INPP5F SIPA1 CDC14A HDAC7 PPP4R4 EPN2 ARFGEF3 MST1R RMDN3 MEGF8 EIF4G1 CEP131 MPHOSPH9 CEP170B

2.52e-13110219440int:YWHAH
InteractionYWHAG interactions

ARHGAP32 NHSL2 ZC3H13 KIF1B MCM3 CLASP2 ARHGEF17 FAM53C PLEKHG1 STOX2 NUAK1 BAIAP2L1 SVIL SIK2 KIF14 COBL AMOTL2 WWC1 RASAL2 TICRR LIMA1 TTC28 CLASP1 APC PTPN21 INPP5F SIPA1 SHROOM2 CDC14A HDAC7 PPP4R4 EPN2 MST1R RMDN3 EIF4G1 CEP131 MPHOSPH9 CEP170B

1.99e-10124819438int:YWHAG
InteractionSFN interactions

ARHGAP32 KIF1B CLASP2 MDM2 ARHGEF17 FAM53C STOX2 NSFL1C SVIL SIK2 KIF14 COBL CCR1 RASAL2 VCPIP1 LIMA1 CLASP1 APC INPP5F HDAC7 PPP4R4 MST1R EIF4G1 CEP131 MPHOSPH9 TNS4 CEP170B

6.47e-1069219427int:SFN
InteractionYWHAB interactions

ARHGAP32 KIF1B CLASP2 ARHGEF17 FAM53C STOX2 NUAK1 BAIAP2L1 SVIL SIK2 KIF14 AMOTL2 WWC1 RASAL2 TICRR LIMA1 TTC28 CLASP1 APC PTPN21 INPP5F SIPA1 CDC14A HDAC7 PPP4R4 EPN2 MST1R RMDN3 EIF4G1 CEP131 MPHOSPH9 CEP170B

2.85e-09101419432int:YWHAB
InteractionYWHAQ interactions

ARHGAP32 ZC3H13 KIF1B MCM3 CLASP2 MDM2 FAM53C STOX2 SVIL SIK2 KIF14 AMOTL2 WWC1 RASAL2 TICRR LIMA1 TTC28 CLASP1 APC INPP5F SIPA1 GRM2 CDC14A HDAC7 PPP4R4 EPN2 MST1R RMDN3 EIF4G1 CEP131 MPHOSPH9 CEP170B

2.90e-08111819432int:YWHAQ
InteractionSFTPC interactions

CNNM2 DAG1 ITGA6 PHC3 CILP2 POM121 TMEM131L PLXNA1 PLXNA3 MST1R CNNM4 MEGF8 CBX8

2.51e-0722219413int:SFTPC
InteractionPPP1CB interactions

TPRN DAG1 MCM3 NUAK1 SVIL SIK2 KIF14 COBL CLEC16A SPATC1L LIMA1 MYO18A TRIOBP SIPA1 HDAC7 CCND3 PPP1R3A EIF4G1

7.04e-0746919418int:PPP1CB
InteractionYWHAE interactions

ARHGAP32 KIF1B CLASP2 FAM53C STOX2 NUAK1 BAIAP2L1 SVIL MTMR2 SIK2 KIF14 AMOTL2 WWC1 RASAL2 TBC1D3F TICRR LIMA1 TTC28 CLASP1 APC PTPN21 INPP5F SHROOM2 CDC14A HDAC7 PPP4R4 MST1R RMDN3 CEP131 MPHOSPH9 CEP170B

1.25e-06125619431int:YWHAE
InteractionMAPRE3 interactions

MYO9B KIF1B NCKAP5 CLASP2 KIF14 COBL TTC28 CLASP1 APC MARCHF7 CEP131 CEP170B

2.48e-0623019412int:MAPRE3
InteractionYWHAZ interactions

ARHGAP32 KIF1B CLASP2 MDH2 MDM2 FAM53C FSIP2 STOX2 BAIAP2L1 SVIL SIK2 KIF14 RASAL2 TICRR LIMA1 TTC28 CLASP1 MYO18A APC PTPN21 INPP5F SIPA1 CDC14A HDAC7 PPP4R4 EPN2 MST1R RMDN3 CEP131 MPHOSPH9 CEP170B

3.44e-06131919431int:YWHAZ
InteractionRHOQ interactions

ARHGAP32 DAG1 ITGA6 SNAP47 PLEKHG1 BAIAP2L1 KIF14 RASAL2 MYO18A TRIOBP KIAA1549 ABCC5 INPP5F ARFGEF3 VAC14 CD44

6.29e-0644219416int:RHOQ
InteractionTOP3B interactions

KMT2B MYO9B KIF1B CUL9 CLASP2 ANKHD1 PPP1R26 PLEKHG1 HEG1 FBXO22 NUAK1 SVIL KIF14 COBL DNA2 TOP3B PLXNA1 DOCK3 PLXNA3 DPH2 LIMA1 FBRSL1 CDC14A HDAC7 CCND3 MST1R VAC14 MEGF8 EIF4G1 CENPV CEP131 CEP170B

1.14e-05147019432int:TOP3B
InteractionBTNL2 interactions

DAG1 ITGA6 CILP2 TMEM131L PLXNA1 PLXNA3 MST1R CNNM4 MEGF8

1.98e-051551949int:BTNL2
InteractionVPS33B interactions

KIF1B HM13 PLEKHG1 KIF14 RFFL ARFGEF3 RMDN3 CEP131 MPHOSPH9 CEP170B

2.40e-0519919410int:VPS33B
InteractionLATS2 interactions

MDM2 PLEKHG1 FBXO22 AMOTL2 TOP3B WWC1 RASAL2 APC KIAA1549 CD44 CEP131 MPHOSPH9

2.49e-0528919412int:LATS2
InteractionPPP1CA interactions

TPRN MCM3 MDM2 PPP1R26 FBXO22 GLI3 MKI67 SIK2 KIF14 CLEC16A LIMA1 AHCTF1 MYO18A APC TRIOBP CCND3 PPP1R3A ARFGEF3 MST1R

4.52e-0569619419int:PPP1CA
InteractionNIN interactions

MCM3 CLASP2 PLEKHG1 SVIL KIF14 VCPIP1 TTC28 CLASP1 APC CDC14A ARFGEF3 CEP131 CEP170B

4.74e-0535919413int:NIN
InteractionIQGAP1 interactions

TPRN SCYL1 ARHGEF17 SVIL SIK2 KIF14 COBL TOP3B NPHS1 LIMA1 MYO18A APC TRIOBP SIPA1 MST1R EIF4G1 CD44

6.11e-0559119417int:IQGAP1
InteractionRNF43 interactions

ARHGAP32 STOX2 POM121 GLI3 SVIL MKI67 TMEM131L TOP3B RASAL2 VCPIP1 TTC28 AHCTF1 APC KIAA1549

7.09e-0542719414int:RNF43
InteractionGOLGA1 interactions

PLEKHG1 AP1AR FBXO22 TTC28 APC ARFGEF3 CEP131 MPHOSPH9 CEP170B

7.26e-051831949int:GOLGA1
InteractionLIMA1 interactions

TPRN FAM53C SVIL MKI67 SIK2 KIF14 COBL TOP3B RASAL2 LIMA1 MYO18A SIPA1 HDAC7 CD44

7.45e-0542919414int:LIMA1
InteractionTRIM36 interactions

KIF1B CLASP2 KIF14 CLASP1 APC CDC14A MPHOSPH9 CEP170B

7.86e-051441948int:TRIM36
InteractionRHOA interactions

ARHGAP32 MYO9B DAG1 ITGA6 HM13 MDM2 ARHGEF17 SNAP47 NDUFV1 NSFL1C BAIAP2L1 ARHGAP31 MKI67 KIF14 CCR1 CLEC16A TOP3B PLXNA1 RASAL2 LIMA1 MYO18A KIAA1549 ABCC5 SIPA1 HDAC7 CD44

8.86e-05119919426int:RHOA
InteractionLGALS1 interactions

DAG1 ITGA6 HEG1 KIF14 PLXNA1 SLC12A6 LIMA1 KIAA1549 MUC16 IGDCC4 CNNM4 CD44

9.47e-0533219412int:LGALS1
InteractionGSK3B interactions

MCM3 CLASP2 MDH2 MDM2 NSFL1C BAIAP2L1 TONSL MKI67 COBL WWC1 RASAL2 VCPIP1 TTC28 CLASP1 APC TRIOBP ARFGEF3 EIF4G1 CENPV CEP131 CEP170B

1.00e-0486819421int:GSK3B
InteractionSYNPO interactions

TPRN ARHGEF17 SVIL KIF14 COBL LIMA1 MYO18A APC CD44

1.05e-041921949int:SYNPO
InteractionTPRN interactions

TPRN KIF14 LIMA1 MYO18A PPP1R3A

1.06e-04491945int:TPRN
InteractionCOBL interactions

FBXO22 KIF14 COBL TOP3B LIMA1 MYO18A

1.06e-04781946int:COBL
InteractionMYO1C interactions

TPRN SVIL KIF14 COBL CLEC16A TOP3B WWC1 LIMA1 CLASP1 MYO18A TRIOBP SIPA1 GRM2

1.30e-0439719413int:MYO1C
InteractionLZTS2 interactions

ARHGAP32 HM13 MDM2 PLEKHG1 KIF14 CLEC16A SPATC1L TTC28 MYO18A FBRSL1 APC SIPA1 CEP131 MPHOSPH9 CBX8

1.37e-0451219415int:LZTS2
InteractionNPAS1 interactions

PI4K2B EPO NHSL2 MCM3 ANKHD1 PHC3 TONSL VCPIP1 MARCHF7 TNS4

1.37e-0424519410int:NPAS1
InteractionRAB35 interactions

ARHGAP32 DAG1 ITGA6 HM13 SNAP47 BAIAP2L1 KIF14 PLXNA1 RASAL2 SLC12A6 APC KIAA1549 ABCC5 INPP5F ARFGEF3 CNNM4

1.42e-0457319416int:RAB35
InteractionGSK3A interactions

CLASP2 BAIAP2L1 GLI3 COBL WWC1 RASAL2 VCPIP1 TTC28 CLASP1 APC RUNX1 ARFGEF3 CEP131 CEP170B

1.69e-0446419414int:GSK3A
InteractionCRTC3 interactions

SCYL1 MDM2 SIK2 KIF14 KIAA1549

1.85e-04551945int:CRTC3
Cytoband4p16.1

USP17L21 USP17L23 USP17L20 USP17L19 USP17L18 USP17L17 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

7.19e-1979204144p16.1
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L23 USP17L20 USP17L19 USP17L18 USP17L17 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.77e-1222220414chr4p16
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RFFL TBC1D3C TBC1D3B

3.98e-1214920412chr17q12
Cytoband17q12

TBC1D3F TBC1D3 TBC1D3H RFFL TBC1D3C TBC1D3B

5.68e-0699204617q12
Cytoband7q34

KIAA1549 TRBV7-7 TRBV7-4 TRBV6-9 TRBV6-5

9.39e-0416720457q34
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R26 MKI67 WWC1 APC PPP1R3A ARFGEF3 TMEM132D

1.96e-041811197694
GeneFamilyPhosphoinositide phosphatases

INPP5D MTMR2 INPP5F

1.20e-033211931079
GeneFamilyPlexins

PLXNA1 PLXNA3

1.50e-0391192683
CoexpressionMADAN_DPPA4_TARGETS

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 PLEKHG1 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.07e-198619817MM1312
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 ABCD4 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.21e-1711219817MM1095
CoexpressionGERY_CEBP_TARGETS

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 WWC1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

5.67e-1516019817MM1155
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

USP17L21 USP17L1 USP17L20 INPP5D ITGA6 USP17L19 MDM2 USP17L18 POM121 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

1.15e-0764719820MM981
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

USP17L21 USP17L1 USP17L20 MCM3 IRF2 USP17L19 MDM2 USP17L18 NSFL1C USP17L17 USP17L3 CCR1 USP17L4 USP17L2 USP17L12 USP17L11 USP17L5 USP17L10 FOXJ3 CCND3 USP17L6P TSHZ1 USP17L22 USP17L15

2.09e-06107219824MM1031
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

RELN PDZD7 STOX2 NRXN3 AJAP1 COBL PDZRN4 TRIM46 PLXNA3 TBC1D3 PCDHGC4 MUC19 MUC16 SHROOM2 SAMD14

7.76e-0650619815M39067
CoexpressionGSE17721_CTRL_VS_LPS_4H_BMDC_UP

MYO9B MDH2 HM13 AP1AR IPPK DPH2 VAC14 CENPV MPHOSPH9

2.27e-052001989M3689
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MYO9B ITGA6 CLASP2 PHF8 HEG1 NUAK1 TMEM131L KIF14 CLEC16A WWC1 TTC28 CLASP1 AHCTF1 APC MARCHF7 INPP5F RUNX1 FOXJ3 MPHOSPH9

2.89e-0585619819M4500
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

CNNM2 INPP5D DACH1 ITGA6 STOX1 PHF8 HSD11B1L ARHGEF17 TUB PLEKHG1 GLI3 TBC1D3G TOP3B TBC1D3K TBC1D3F DOCK3 TBC1D3 TBC1D3H TBC1D3L PCDHGC4 TTC28 TBC1D3D PRR36 TBC1D3C TBC1D3B IGDCC4 BARHL1 POLI SAMD14 TINCR

1.54e-08107518530PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

9.16e-08901859PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

DACH1 STOX1 PHF8 HSD11B1L ARHGEF17 PLEKHG1 NUAK1 GLI3 SVIL SIK2 AMOTL2 TBC1D3G CLEC16A TOP3B PLXNA1 TBC1D3K TBC1D3F DOCK3 PLXNA3 TBC1D3 TBC1D3H TBC1D3L PCDHGC4 TTC28 TBC1D3D PTPN21 TBC1D3C TBC1D3B IGDCC4 BARHL1 POLI SAMD14 TINCR

4.30e-07146618533PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

SVIL TONSL TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IGDCC4

6.98e-0628118512PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

SVIL TONSL TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IGDCC4

6.98e-0628118512PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

RELN TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L PGGHG TBC1D3D TBC1D3C TBC1D3B IGDCC4

2.55e-0532018512PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L PGGHG TBC1D3D TBC1D3C TBC1D3B

5.44e-0524218510PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.09e-042131859PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.09e-042131859PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

EPO RELN ZC3H13 DACH1 NCKAP5 STOX2 HEG1 GLI3 MKI67 TMEM131L KIF14 DNA2 RASAL2 TICRR CLASP1 PRR36 APC KIAA1549 USP17L10 CDC14A GPATCH3 SAMD14

1.45e-04106018522facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

KIF1B DACH1 NCKAP5 MDM2 PLEKHH1 STOX2 NRXN3 INPP5F CDC14A

1.64e-042251859Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K4
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

EPO RELN ZC3H13 DACH1 NCKAP5 UNC5A STOX2 HEG1 NRXN3 GLI3 MKI67 TMEM131L KIF14 DNA2 RASAL2 DOCK3 TICRR CLASP1 PRR36 APC KIAA1549 USP17L10 CDC14A GPATCH3 TNS4 SAMD14

2.45e-04141418526facebase_RNAseq_e10.5_Emin_MedNas_2500
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 IGSF10 PLEKHG1 RASAL2 CYP26B1 TTC28 HDAC7 PPP1R3A

1.33e-061801958dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 IGSF10 PLEKHG1 RASAL2 CYP26B1 TTC28 HDAC7 PPP1R3A

1.33e-061801958423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGA6 PGM5 PLEKHG1 STOX2 HEG1 NUAK1 ARHGAP31 RASAL2

1.51e-061831958ff95382cfed592190d0636d2b750328471f82e0d
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NHSL2 PLEKHG1 ARHGAP31 SIK2 TMEM131L SLC12A6 MYO18A TSHZ1

1.92e-061891958bccb3481ffed597c845fe860da658505316105b5
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 STOX2 ARHGAP31 AMOTL2 RASAL2 CYP26B1 HDAC7 PPP1R3A

2.00e-061901958a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 STOX2 ARHGAP31 AMOTL2 RASAL2 CYP26B1 HDAC7 PPP1R3A

2.00e-06190195825525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

BICDL2 BDKRB2 NRXN3 BAIAP2L1 MUC16 AQP5 ARFGEF3 TNS4

2.00e-06190195851ca9ef4df3220487152fcf684147730637c7cc1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN INPP5D PGM5 PLEKHG1 HEG1 NUAK1 ARHGAP31 RASAL2

2.08e-061911958f663131a4810584c5854bd64ee7991a237b7707f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 AJAP1 SVIL COBL CLEC16A WWC1 DOCK3 CD44

2.08e-0619119589032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 AJAP1 SVIL COBL CLEC16A WWC1 DOCK3 CD44

2.08e-0619119585717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 PLEKHG1 AMOTL2 RASAL2 CYP26B1 TTC28 HDAC7 PPP1R3A

2.24e-061931958826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INPP5D DACH1 ITGA6 NCKAP5 PLEKHG1 HEG1 ARHGAP31 CDC14A

2.24e-061931958e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 PLEKHG1 AMOTL2 RASAL2 CYP26B1 TTC28 HDAC7 PPP1R3A

2.24e-06193195887d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 PLEKHG1 AMOTL2 RASAL2 CYP26B1 TTC28 HDAC7 PPP1R3A

2.24e-061931958d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

RELN ADGRG4 NRXN3 MUC16 MALRD1 KRT75 TMEM132D

2.72e-06139195764c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 STOX2 BAIAP2L1 COBL WWC1 MUC16 AQP5 ARFGEF3

2.92e-062001958d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ITGA6 STOX2 SVIL COBL WWC1 MUC16 ARFGEF3

2.92e-0620019580eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA6 PLEKHH1 GLI2 COBL SEC16B MUC16 AQP5 ARFGEF3

2.92e-06200195885c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellP28-Epithelial-epithelial_progenitor_cell-epi_progenitor|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PI4K2B CCDC88B WWC1 PLXNA3 AQP5 PPP1R3A ARFGEF3

5.58e-061551957be575a0096415705dba425002247289ff8f89474
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL2 BCORL1 PGM5 HEG1 NUAK1 GLI3 HDAC7

8.74e-0616619579d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NHSL2 QRICH2 NUAK1 DPH2 ITGA10 KIAA1549 GPATCH3

1.06e-0517119571ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 PGM5 CILP2 HEG1 NRXN3 AMOTL2 PPP4R4

1.10e-051721957f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 PGM5 CILP2 HEG1 NRXN3 AMOTL2 PPP4R4

1.10e-0517219576ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DHRS13 MCM3 PPP1R26 MKI67 DNA2 ITGA10 SHROOM2

1.10e-0517219577c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

DACH1 PLEKHG1 AJAP1 ARHGAP31 RASAL2 ITGA10 SHROOM2

1.48e-051801957b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CCDC88B NRXN3 C1QTNF4 DNA2 CD44 SAMD14

1.48e-0518019576ac62bf1251978c8c12e715f7b73144fca619794
ToppCelldroplet-Lung-nan-21m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR38 BAIAP2L1 COBL AQP5 OPRD1 ARFGEF3 BARHL1

1.59e-05182195740539ade8c3cd12b61f1cd0d493828e58282796b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 SVIL DOCK3 TBC1D3C CDC14A CCND3 CD44

1.71e-051841957d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

NCKAP5 COBL AMOTL2 WWC1 RASAL2 PGGHG PTPN21

1.77e-05185195732b4e68e551d435a732f253f6ad83408c759a642
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INPP5D PGM5 PLEKHG1 HEG1 NUAK1 ARHGAP31 RASAL2

1.89e-05187195735c382c0aabd46906113e5db30ea24bb8e658899
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGM5 STOX2 AMOTL2 RASAL2 CYP26B1 HDAC7 PPP1R3A

1.96e-0518819570aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL2 ITGA6 PLEKHG1 HEG1 ARHGAP31 RASAL2 HDAC7

1.96e-0518819570026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

DACH1 ITGA6 PLEKHG1 NRXN3 ITGA10 KIAA1549 SHROOM2

1.96e-05188195702a62888e9db29d20133eeca1686d302545a39c9
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 STOX2 NRXN3 WWC1 DOCK3 ARFGEF3 TMEM132D

2.03e-0518919577659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA6 PLEKHH1 PLEKHG1 NRXN3 PIK3C2G WWC1 DOCK3

2.10e-051901957625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B BAIAP2L1 COBL WWC1 AQP5 ARFGEF3 TMEM132D

2.17e-051911957c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BICDL2 NCKAP5 PLEKHG1 WWC1 ABCC5 AQP5 ARFGEF3

2.17e-05191195723776c7302cead3881b39127398f3b3e0d27885e
ToppCellfacs-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B BAIAP2L1 COBL WWC1 AQP5 ARFGEF3 TMEM132D

2.17e-0519119575f43f98cfe7a08d61ed55f34808fabfe47f1ac2e
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMOTL2 MUC16 PTPN21 SHROOM2 AQP5 PPP4R4 MST1R

2.24e-0519219578899d81306770adda893b5e146df1253971754c5
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMOTL2 MUC16 PTPN21 SHROOM2 AQP5 PPP4R4 MST1R

2.24e-0519219575fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

NHSL2 PLEKHG1 HEG1 NRXN3 ITGA10 SHROOM2 CCND3

2.32e-05193195701c2df9206f1527c578e808978e58196c35e72f5
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INPP5D DACH1 ITGA6 NCKAP5 PLEKHG1 HEG1 ARHGAP31

2.32e-0519319576e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

BICDL2 NCKAP5 PLEKHG1 NRXN3 WWC1 ABCC5 ARFGEF3

2.32e-0519319572bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL2 AJAP1 SVIL CLEC16A WWC1 HDAC7 CCND3

2.32e-051931957263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL2 AJAP1 SVIL CLEC16A WWC1 HDAC7 CCND3

2.32e-05193195780e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BICDL2 AJAP1 SVIL CLEC16A WWC1 HDAC7 CCND3

2.32e-051931957b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACH1 ITGA6 NCKAP5 PLEKHG1 HEG1 ARHGAP31 RASAL2

2.40e-0519419570b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

BICDL2 NCKAP5 PLEKHG1 WWC1 ABCC5 AQP5 ARFGEF3

2.48e-051951957dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PI4K2B ARHGAP32 PLEKHH1 WWC1 MUC16 AQP5 ARFGEF3

2.48e-051951957e7230a849ea31e6eef9bc6f5468938499450582d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NHSL2 DAG1 STOX2 SLC12A6 CDC14A CBX8

2.55e-05132195614a512f433315892bf0326419f23d0d5919d01ec
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

RELN PGM5 PLEKHG1 STOX2 NUAK1 ARHGAP31 RASAL2

2.56e-051961957e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN INPP5D PLEKHG1 HEG1 NUAK1 ARHGAP31 TTC28

2.56e-051961957b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NCKAP5 COBL AMOTL2 PLXNA1 WWC1 PTPN21 AQP5

2.56e-051961957150554fa06868d29b0608189862eef6505ba757f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN INPP5D PLEKHG1 HEG1 NUAK1 ARHGAP31 TTC28

2.56e-051961957145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DACH1 ITGA6 PLEKHG1 NRXN3 ARHGAP31 TTC28 SHROOM2

2.56e-051961957ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN INPP5D PLEKHG1 HEG1 NUAK1 ARHGAP31 TTC28

2.56e-051961957d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

DACH1 DAG1 HEG1 GLI3 MKI67 AMOTL2 WWC1

2.64e-05197195761749ccafeb938c310cff1de5ff924a1c794325a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INPP5D PGM5 PLEKHG1 HEG1 NUAK1 ARHGAP31 RASAL2

2.64e-0519719570f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

DACH1 DAG1 HEG1 GLI3 MKI67 AMOTL2 WWC1

2.64e-0519719579d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NCKAP5 PLEKHG1 WWC1 ABCC5 RUNX1 ARFGEF3 TMEM132D

2.73e-0519819571408e02e053ad3406229bfe8189da03be6366e81
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MCM3 NCKAP5 TONSL MKI67 KIF14 DNA2 TICRR

2.82e-0519919571d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GLI2 COBL SEC16B KIAA1549 MUC16 AQP5 ARFGEF3

2.91e-052001957ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA6 STOX2 COBL WWC1 DOCK3 ZNF652 ARFGEF3

2.91e-0520019577c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ITGA6 STOX1 GLI2 TOP3B AHCTF1 HDAC7 IGDCC4

2.91e-052001957b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

DACH1 MCM3 STOX1 GLI3 DNA2 CDC14A TSHZ1

2.91e-0520019574a57d6ba1531ce4e263daccd5de487977e6a1fdd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Stem_cells-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

DACH1 MCM3 STOX1 GLI3 DNA2 CDC14A TSHZ1

2.91e-052001957b706526b9c3485889a31253a1ffd017ad3f3fddc
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R-|Neuronal / cells hierarchy compared to all cells using T-Statistic

NHSL2 DACH1 ITGA6 PDZRN4 SEC16B GRM2 TSHZ1

2.91e-052001957891a80cbde575f81f3466217175f41e1d4f66d5e
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R|Neuronal / cells hierarchy compared to all cells using T-Statistic

NHSL2 DACH1 ITGA6 PDZRN4 SEC16B GRM2 TSHZ1

2.91e-052001957c761d1742653a83e69e4c03d6e10e5e53f28bebb
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

NHSL2 DACH1 ITGA6 PDZRN4 SEC16B GRM2 TSHZ1

2.91e-052001957dcbc91ed3351bafd72cf71d7025cbbdc8361d9b9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

BICDL2 SHISA6 WWC1 MUC19 AQP5 TMEM132D

7.22e-0515919568680b054622f573a82b1625fb93c2d5db81d1034
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NCKAP5 COBL AMOTL2 PGGHG AQP5 TMEM132D

8.01e-051621956ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TONSL MKI67 KIF14 DNA2 TICRR CEP131

8.86e-05165195688681101d7cf60b99b8ace5d8c0944323b937306
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF10 ABCD4 CCR1 HDAC7 GPATCH3 TNS4

9.16e-05166195613027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF10 ABCD4 CCR1 HDAC7 GPATCH3 TNS4

9.16e-051661956b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDZD7 CILP2 NUAK1 PDZRN4 ITGA10 KIAA1549

9.47e-0516719567b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellControl|World / group, cell type (main and fine annotations)

NCKAP5 STOX2 NRXN3 BAIAP2L1 COBL ARFGEF3

9.79e-051681956a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

ARHGEF17 PLEKHG1 SHISA6 PDZRN4 PCDHGC4 CDC14A

9.79e-05168195600646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

NCKAP5 PLEKHG1 STOX2 HEG1 COBL RASAL2

1.04e-041701956e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRXN3 SVIL SHISA6 LIMA1 INPP5F AQP5

1.08e-0417119565efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FSIP2 COBL PTPN21 AQP5 MST1R MALRD1

1.11e-0417219560be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

BICDL2 NCKAP5 WWC1 MYO18A AQP5 MST1R

1.19e-041741956edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

NCKAP5 STOX2 COBL PGGHG PTPN21 TMEM132D

1.19e-041741956548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

BICDL2 NCKAP5 WWC1 MYO18A AQP5 MST1R

1.19e-04174195665539f69100db0b7d90b1b39ee15ab8281f86461
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R26 C1QTNF4 WWC1 SEC16B AQP5 ARFGEF3

1.22e-04175195696219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R26 C1QTNF4 WWC1 SEC16B AQP5 ARFGEF3

1.22e-041751956cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 HEG1 NUAK1 ARHGAP31 ITGA10 HDAC7

1.30e-041771956fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA6 HEG1 NUAK1 ARHGAP31 ITGA10 HDAC7

1.30e-04177195612f8627124acbf436e75681ff1ce429ff5e3f256
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 TPRN RASAL2 ACAP3 CYP26B1 ITGA10

1.38e-041791956025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NCKAP5 NRXN3 WWC1 ABCC5 ARFGEF3 TMEM132D

1.43e-041801956b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 PGM5 PLEKHG1 RASAL2 TTC28 HDAC7

1.47e-041811956fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL2 ITGA6 PLEKHG1 ARHGAP31 PZP RASAL2

1.52e-04182195663b41b538b26bc899558807fd035e543611f8c52
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

BICDL2 NCKAP5 PLEKHG1 WWC1 ABCC5 ARFGEF3

1.52e-041821956215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BICDL2 STOX1 NRXN3 SHISA6 MUC16 ARFGEF3

1.52e-0418219563f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 HEG1 NUAK1 ARHGAP31 RASAL2 CYP26B1

1.56e-041831956dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PI4K2B BICDL2 BAIAP2L1 COBL WWC1 ARFGEF3

1.56e-04183195623e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA6 HEG1 NUAK1 ARHGAP31 RASAL2 CYP26B1

1.56e-0418319564759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPPK PGGHG MYO18A EPN2 CCND3 MEGF8

1.56e-0418319563ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial-AT2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PI4K2B BICDL2 BAIAP2L1 COBL WWC1 ARFGEF3

1.56e-0418319560a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DACH1 ITGA6 PGM5 HEG1 NUAK1 ARHGAP31

1.56e-041831956c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

NCKAP5 COBL PLXNA1 WWC1 PGGHG AQP5

1.61e-041841956cb15d6bae52c5ec251c2235859dc7e65f630ae23
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A

ARHGAP32 DAG1 ITGA6 GLI3 SVIL TMEM131L PLXNA1 TTC28 APC SHROOM2 HDAC7 EPN2

1.58e-08177178124652_DN
DrugBM-I

MDM2 RUNX1 CD44 CBX8

1.70e-06121784CID016058649
DrugPHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A

CNNM2 IRF2 FBXO22 ABCD4 SIK2 CLEC16A RASAL2 PTPN21 RUNX1 CDC14A

3.62e-06197178106545_DN
DrugPaclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A

PHF8 MDM2 HEG1 AJAP1 TOP3B CYP26B1 RUNX1 HDAC7 GPATCH3

2.39e-0519517891542_UP
DrugNalidixic acid sodium salt hydrate; Down 200; 14.6uM; HL60; HT_HG-U133A

ARHGAP32 IRF2 PDZD7 PHC3 SVIL CLEC16A LIMA1 RUNX1 FAM3A

2.39e-0519517892336_DN
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A

MYO9B BCORL1 DACH1 DAG1 FBXO22 PLXNA1 CLASP1 PRR36 VAC14

2.49e-0519617891692_DN
DrugMecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; PC3; HT_HG-U133A

CNNM2 AP1AR NRXN3 WWC1 IPPK RUNX1 FOXJ3 VAC14 CBX8

2.49e-0519617897263_UP
DrugFoliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A

MDM2 FAM53C FBXO22 CLEC16A APC RUNX1 PPP4R4 CEP170B CBX8

2.59e-0519717894295_DN
DrugOrlistat; Down 200; 10uM; PC3; HT_HG-U133A

CNNM2 PRR36 APC ZNF343 PTPN21 RUNX1 EPN2 MEGF8 CBX8

2.70e-0519817896388_DN
Drugtopiramate; Up 200; 3uM; MCF7; HT_HG-U133A_EA

BCORL1 PHC3 GLI3 APC PTPN21 FOXJ3 EPN2 FAM3A CEP131

2.70e-051981789915_UP
Drugmitoxantrone

TONSL TOP3B PLXNA1 ABCC5 RUNX1 IGDCC4 TMEM132D CEP170B

2.95e-051541788CID000004212
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L21 USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

4.41e-264619117DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP17L21 KMT2B USP17L1 USP17L20 USP17L19 USP17L18 USP17L17 USP17L3 USP17L4 USP17L2 USP17L12 USP17L11 USP17L24 USP17L5 USP17L10 USP17L6P USP17L22 USP17L15

2.27e-246919118DOID:1682 (implicated_via_orthology)
Diseasemacrophage inflammatory protein 1b measurement

DAG1 TOP3B TBC1D3F DOCK3 TBC1D3 GRM2 TBC1D3B

3.08e-051361917EFO_0008219
Diseaseplatelet crit

EPO MYO9B NHSL2 DACH1 DAG1 SVIL TMEM131L RASAL2 TTC28 NOC3L ABCC5 MARCHF7 RUNX1 HDAC7 CCND3 MPHOSPH9 CBX8

1.64e-0495219117EFO_0007985
Diseasemean platelet volume

EPO ARHGAP32 MYO9B KIF1B BCORL1 ITGA6 MCM3 SVIL TMEM131L SLC12A6 PCDHGC4 TTC28 FBRSL1 ABCC5 RUNX1 HDAC7 OPRD1

3.65e-04102019117EFO_0004584
Diseasecortical surface area measurement

RELN CNNM2 MYO9B ZC3H13 KIF1B CUL9 NCKAP5 STOX1 PLEKHG1 NUAK1 ARHGAP31 GLI3 MTMR2 WWC1 PDZRN4 TICRR APC TRIOBP MARCHF7 MPHOSPH9

4.82e-04134519120EFO_0010736
DiseaseLiver carcinoma

EPO KMT2B IRF2 TONSL MKI67 KIF14 CCR1 PZP TICRR APC CEP131

4.99e-0450719111C2239176
DiseasePROSTATE CANCER, HEREDITARY, 1

MYO9B TTC28 FBRSL1 TSHZ1

6.25e-04601914C4722327
Diseaseganglion cell inner plexiform layer thickness measurement

TDRD9 STOX2 COBL

7.76e-04281913EFO_0600005
Diseasesclerosing cholangitis

CCDC88B SIK2 CLEC16A HDAC7

8.96e-04661914EFO_0004268
DiseaseEczema

INPP5D CCDC88B SIK2 CLEC16A TTC28 ZNF652 RUNX1 POLI

9.78e-043101918HP_0000964
Diseaseadult onset asthma

SCYL1 SIK2 CLEC16A RUNX1 HDAC7

1.04e-031181915EFO_1002011
DiseaseProstate cancer, familial

MYO9B TTC28 FBRSL1 TSHZ1

1.06e-03691914C2931456
Diseaselateral ventricle volume measurement

NUAK1 CLEC16A TRIOBP

1.26e-03331913EFO_0008487
Diseaseclopidogrel metabolite measurement

MYO18A RFFL TBC1D3B

1.26e-03331913EFO_0007966
DiseaseLynch Syndrome

APC CD44

1.46e-0391912C4552100
DiseaseGastrointestinal Hemorrhage

RELN APC

1.46e-0391912C0017181
DiseaseBMI-adjusted waist-hip ratio, adult onset asthma

SCYL1 SIK2

1.46e-0391912EFO_0007788, EFO_1002011
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

GLI2 GLI3

1.46e-0391912DOID:0050338 (implicated_via_orthology)
Diseaseallergic disease

INPP5D SIK2 CLEC16A ZNF652 RUNX1 HDAC7 POLI

1.52e-032581917MONDO_0005271
Diseaserefractive error, age at onset, Myopia

TDRD9 AMOTL2 PZP SHISA6 MEI1 TBC1D3B

1.66e-031931916EFO_0004847, HP_0000545, MONDO_0004892
Diseaseage of onset of asthma

CLEC16A TTC28 RUNX1 HDAC7

1.75e-03791914OBA_2001001
Diseaseage at onset, multiple sclerosis

RELN NCKAP5

1.81e-03101912EFO_0004847, MONDO_0005301
Diseasenucleus accumbens volume change measurement

WWC1 MUC16

2.21e-03111912EFO_0021493
Diseasemean corpuscular hemoglobin concentration

CNNM2 MYO9B DAG1 MDM2 MTMR2 TICRR CYP26B1 TTC28 CLASP1 FBRSL1 ABCC5 RUNX1 HDAC7 OPRD1 IGDCC4 CCND3

2.33e-03110519116EFO_0004528
Diseasecolorectal cancer, endometrial neoplasm

LIMA1 MALRD1 TSHZ1

2.55e-03421913EFO_0004230, MONDO_0005575
Diseasewaist-hip ratio

MYO9B DAG1 CUL9 WDR38 SSC5D NRXN3 GLI3 CLEC16A SHISA6 PDZRN4 IPPK SEC16B TTC28 RUNX1 SIPA1 PPP1R3A MEGF8

2.67e-03122619117EFO_0004343
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

PDZD7 TRIOBP

3.10e-03131912C1846647
Diseasereceptive language perception, parental genotype effect measurement

PLEKHG1 MUC19

3.60e-03141912EFO_0005686, EFO_0005939
Diseasereaction time measurement

NCKAP5 CCDC88B POM121 PDZRN4 TTC28 FBRSL1 MUC19 APC POLI TSHZ1 RFPL3

3.90e-0365819111EFO_0008393
Diseaseeosinophil percentage of granulocytes

INPP5D CLEC16A DOCK3 ZNF652 RUNX1 PPP1R3A

4.31e-032341916EFO_0007996
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

TPRN TRIOBP CDC14A

4.43e-03511913cv:CN043650
Diseasedevelopmental dysplasia of the hip

AJAP1 SHISA6

4.71e-03161912EFO_1000648
DiseasePolyposis, Adenomatous Intestinal

APC CD44

4.71e-03161912C2713442
DiseaseFamilial Intestinal Polyposis

APC CD44

4.71e-03161912C2713443
DiseaseDiuretic use measurement

DACH1 PLEKHG1 SIK2 TICRR ZNF652

4.97e-031691915EFO_0009928
DiseaseAdenomatous Polyposis Coli

APC CD44

5.32e-03171912C0032580
DiseaseRheumatoid Arthritis

ITGA6 BDKRB2 BAIAP2L1 ABCC5 RUNX1

5.61e-031741915C0003873
Diseaseresponse to calcium channel blocker

DOCK3 MUC19 GRM2

5.75e-03561913EFO_0007767
DiseaseColorectal Carcinoma

GLI3 MKI67 ABCD4 PZP RASAL2 PDZRN4 APC ABCC5 CDC14A EIF4G1 TNS4

6.26e-0370219111C0009402
DiseaseAgents acting on the renin-angiotensin system use measurement

CNNM2 MYO9B PLEKHG1 SIK2 TICRR SIPA1 HDAC7

6.37e-033351917EFO_0009931

Protein segments in the cluster

PeptideGeneStartEntry
SSSERQTADAPARLT

AMOTL2

686

Q9Y2J4
ERSRELSAESFLPTA

FBRSL1

251

Q9HCM7
LSVREDSVPTTASFS

BDKRB2

11

P30411
LRESLREASQTSSSP

CCND3

251

P30281
LSSRFPVGRSSESFS

CCDC88B

1396

A6NC98
PSTLARAFSTSVLSD

ADGRG4

1036

Q8IZF6
SARFLSRSIPSLQSE

CDC14A

576

Q9UNH5
PSARVAVLFTRSEDA

GRM2

261

Q14416
PAQSRTVTSSFLIRD

BARHL1

86

Q9BZE3
SSFRDFIPVVLSTRT

BCORL1

1211

Q5H9F3
RSASSEEASESPTAR

BCORL1

1466

Q5H9F3
SFDSRGSRPTTETEF

AJAP1

166

Q9UKB5
SELRSAFSAARTTPL

C1QTNF4

26

Q9BXJ3
ELAESSPAASFLSSR

DPH2

441

Q9BQC3
ERLDRTASPSTSSID

ACAP3

376

Q96P50
EVFRSSRLSSDATVL

AP1AR

166

Q63HQ0
AFLLERVSISAPSSD

ABCD4

386

O14678
ESPELSRASSATFRP

CEP170B

596

Q9Y4F5
ASAAEAVRSSTSRPR

HSD11B1L

216

Q7Z5J1
VSSSPARTESSSDRI

DACH1

516

Q9UI36
SASVLSRPEASRTGE

ATP5MC3

26

P48201
IFASTDSRRTSPVGS

AQP5

146

P55064
PEALSRTRASTARFV

IGDCC4

341

Q8TDY8
VSFTLPRISASSEVA

PZP

86

P20742
TAESCRSTPLTVDRS

PDZRN4

741

Q6ZMN7
VTLFRSPDSVDRVLS

QRICH2

986

Q9H0J4
SSRSRFAFSVSVLDL

IPPK

426

Q9H8X2
SSSSRPDRETRASVI

IRF2

321

P14316
ADDSRFSILAPSFTS

PIK3C2G

136

O75747
TFRSAFRTSEGIVPT

KIAA1549

231

Q9HCM3
DASRLIFRLSSSSGV

PGM5

501

Q15124
IAASYPVSRSRAASS

ARHGEF17

236

Q96PE2
RGSSVDPRSTFVLSN

FBXO22

11

Q8NEZ5
RTISLPTSESLVSFR

MUC16

2181

Q8WXI7
ESTRARTEPNSFLTI

MUC16

4001

Q8WXI7
RLRETSTSQESSFPT

MUC16

5191

Q8WXI7
SSRTSISDLDRPTIA

MUC16

5526

Q8WXI7
TSVLTSTPAFLETRR

MUC16

7806

Q8WXI7
FTVEATARVTPRSSD

NPHS1

196

O60500
SASEPRAASRVSAVS

FBXW9

61

Q5XUX1
DITDAPVSSLSRRRS

KIF14

1176

Q15058
DPISTDASRRSSEAS

GLI3

896

P10071
SSSLKERSRPFTVAA

LIMA1

581

Q9UHB6
ERSRPFTVAASFQST

LIMA1

586

Q9UHB6
SESTTCLFRTRPLDA

WWC1

706

Q8IX03
DRAARATSPRVSSEL

EPN2

251

O95208
NERLADRTPSPTFST

KIF1B

901

O60333
ARPASAALRRSFSTS

MDH2

6

P40926
VELASTSRFELATRT

CYP26B1

456

Q9NR63
RSVSDSSVPRRDSLS

KIAA1109

4366

Q2LD37
PDPRDIFSERSSLSS

FRMD7

431

Q6ZUT3
RSFRVTIPTDLIASS

DAG1

76

Q14118
RVSSDLPTSVRSSVE

FSIP2

3201

Q5CZC0
TSATDVRPLSTRDST

GPATCH3

81

Q96I76
SPARVTALRFNSSSL

PLXNA1

751

Q9UIW2
SRYESLLRTASSPDS

PLXNA3

1596

P51805
SSRESVTTRPLAEGS

MUC19

2146

Q7Z5P9
EESRTTRPSAGITAT

MUC19

6106

Q7Z5P9
RTTRSEAPGEATTLT

MUC19

6741

Q7Z5P9
ASSRRVSSSSELDLP

MYO18A

1061

Q92614
STPSDTSSEDGVRRI

PDZD7

196

Q9H5P4
ISVNSRRTPFTASGE

NRXN3

556

Q9Y4C0
PSTRSDRLAVGFSTT

NRXN3

1111

Q9Y4C0
PSTARFSVRVNSTEL

MEGF8

411

Q7Z7M0
VRPSRANTLATSDVS

MPHOSPH9

661

Q99550
DRNTSFRLPSLRSTD

RASAL2

61

Q9UJF2
STSADNFSPDLRVLR

MTMR2

51

Q13614
DPISTDASRRSSEAS

GLI2

856

P10070
TSRDAARFPIIASCT

HM13

71

Q8TCT9
SASETESVPSRSRRG

KMT2B

911

Q9UMN6
SVLLSPSAVESRRNS

HEG1

371

Q9ULI3
VGSLSDSVTIFRSRP

ITGA6

491

P23229
ARRVSRSSFSSDPDE

MKI67

121

P46013
SSSSEFPGRTFSDVR

PGGHG

696

Q32M88
EPRNRDVSASSFISL

PCDHGC4

496

Q9Y5F7
VSRGTAPSDNRVTSF

NSFL1C

61

Q9UNZ2
RRPRSSSDALSASFN

ARHGAP32

726

A7KAX9
ESPSLESRSTAVTRT

PHC3

271

Q8NDX5
TDSSSADPVRLEFSR

RELN

2031

P78509
ISSRSPESLAFLSDR

MEI1

666

Q5TIA1
DPSSFSRAREATARE

OPRD1

341

P41143
TLSASAAEVAPRAVS

PTPN21

656

Q16825
TPSSGTRRVSFADSF

PPP1R3A

56

Q16821
SSSAELDRSRPAVSV

PI4K2B

76

Q8TCG2
DTARTSPVTARTLET

MCM3

606

P25205
RFSRSAIPEQIISST

POM121

281

Q96HA1
FTSPESSVTAAPRAR

FAM3A

41

P98173
ISSSLRSRVFLPTND

MALRD1

126

Q5VYJ5
TVRLASETEARFTSV

ABCC5

1146

O15440
LPARTVTADSRTISD

IGSF10

816

Q6WRI0
RRADSARTTSTFKAP

BAIAP2L1

451

Q9UHR4
TSTSSTCRAEAPRDR

CBX8

136

Q9HC52
SIARTVDSRLFSFSE

DOCK3

836

Q8IZD9
EDFISSTISTTPRAF

CD44

301

P16070
LSVDRLERVSSTSPS

CCR1

331

P32246
TILSPTASREDRALT

CROCC2

31

H7BZ55
ARSVERASTPYSIDS

FOXJ3

171

Q9UPW0
ASAATESPFAQSRRI

ARFGEF3

836

Q5TH69
TSSQEASSASEPRRA

COBL

1001

O75128
AAAALAPSATRTRRS

CENPV

31

Q7Z7K6
AASAAPLRTITADTF

EPO

151

P01588
ELSASASSSTPRRAA

BICDL2

471

A1A5D9
SDAASEAARPATSTL

EIF4G1

1106

Q04637
EAARPATSTLNRFSA

EIF4G1

1111

Q04637
RDESSRIPTSDTSSR

MARCHF7

406

Q9H992
SSFLREIRTIASDPD

ITGA10

316

O75578
ETSRNPLSRAASFAS

CUL9

1406

Q8IWT3
EFTPQSILRSTLRST

AHCTF1

1196

Q8WYP5
SQARVLSSSETPART

HDAC7

501

Q8WUI4
VLSETFRSSDPATRQ

DNA2

141

P51530
RVSSLRFLQAPSASS

FAM53C

166

Q9NYF3
STRTRESPLDTTNFS

POLI

496

Q9UNA4
SRVRFSSRESVPETS

SLC12A6

41

Q9UHW9
ESSSSRAVSPFAKIR

INPP5F

1061

Q9Y2H2
EESSSALTRALRAEF

CEP131

826

Q9UPN4
SVRAFATAFLSSEPR

DHRS13

101

Q6UX07
TSLIPATFTAASRDA

nan

576

A6NNC1
RVSFLTRDLSSSEPV

NOC3L

106

Q8WTT2
SSRLSTAPDLTAFSD

RUNX1

291

Q01196
SVFTAASTERAPVTL

VAC14

381

Q08AM6
RDGSRLSASTVPLTF

RFPL1

221

O75677
RFPFVRERSDSTGSS

RMDN3

141

Q96TC7
RATEALQTFRPAASS

TRIM46

391

Q7Z4K8
ADDSFRTRNASSVPS

PPP4R4

816

Q6NUP7
EDALVLRSARTSSPA

SNAP47

351

Q5SQN1
SFSGRDSSFTEVPRS

SVIL

231

O95425
SRDISIVFTPDFTSS

TMEM131L

811

A2VDJ0
TFPVSISRNSTEDRF

TMEM132D

306

Q14C87
RVLTSAFSRATRDPF

SCYL1

466

Q96KG9
PAAAFERSLSQRSSE

TDRD9

66

Q8NDG6
VPRVSTESFSSRTVT

NCKAP5

751

O14513
ASRFRERSLSVPTDS

NHSL2

491

Q5HYW2
SQEDRTRASTLSPDF

RFFL

141

Q8WZ73
SLPARVSVRFSGDTT

NDUFV1

11

P49821
PSTRSDRLAVGFSTT

NRXN3

106

Q9HDB5
PLDESRASITSVTSF

PRR36

1311

Q9H6K5
RASITSVTSFSPDDV

PRR36

1316

Q9H6K5
PSTSSRRRAISETEE

MDM2

156

Q00987
RATETSRPSLSETLF

INPP5D

151

Q92835
SPVSFREGRRASDTS

SIK2

576

Q9H0K1
EEASRPAATSTRLFT

SIPA1

76

Q96FS4
SRLQASLSSSDVRFP

SHROOM2

406

Q13796
ERTAFPEQSLSRAIS

SHISA6

411

Q6ZSJ9
PSRSRLRDSASSAED

SAMD14

46

Q8IZD0
LSRSYSRPSSVISDD

NUAK1

561

O60285
PASRSEFVERSSCRA

PPP1R26

461

Q5T8A7
AALTTEASRRPTSEF

SSC5D

666

A1L4H1
RVRSAFAAPSTDSDQ

TBC1D3L

501

B9A6J9
VCFSESSLPTGDRTR

SPATC1L

161

Q9H0A9
TAQAASTREIPRASS

TRIOBP

266

Q9H2D6
FADPEVLRRLTSSVS

ANKHD1

166

Q8IWZ3
LEESASFESLSPSSR

APC

2456

P25054
RVTFVDPRDLTSAAS

CILP2

606

Q8IUL8
TSAASAPSDLRFVDS

CILP2

616

Q8IUL8
RGSSDPTVQRSVFAS

CLEC16A

861

Q2KHT3
TSRESSRDTSPARGF

CLASP1

756

Q7Z460
EASRESSRDTSPVRS

CLASP2

531

O75122
SLSRSDRIDAVTPTL

CNNM2

761

Q9H8M5
RSASLSYPDRTDVST

CNNM4

661

Q6P4Q7
RVRSAFAAPSTDSDQ

TBC1D3B

501

A6NDS4
RVRSAFAAPSTDSDQ

TBC1D3H

501

P0C7X1
TVFRARFSSITDTDI

TOP3B

146

O95985
TSSRPDAAFAEIQRT

USP17L3

21

A6NCW0
SARTEERETSRAFPS

ZNF343

181

Q6P1L6
TAVADSPRDTASLFS

TICRR

436

Q7Z2Z1
SPRDTASLFSDVVDS

TICRR

441

Q7Z2Z1
STVEDSPFSRAFSRR

TICRR

1876

Q7Z2Z1
TSSRPDAAFAEIQRT

USP17L4

21

A6NCW7
RVRSAFAAPSTDSDQ

TBC1D3F

501

A6NER0
LSRDVPRETRSSSES

TNS4

186

Q8IZW8
PRETRSSSESLIFSG

TNS4

191

Q8IZW8
ASFSDRTPSACRLVD

STOX1

646

Q6ZVD7
SITVDSGFNSPRTRE

STOX2

851

Q9P2F5
PASNREAATASTSRA

TONSL

776

Q96HA7
TSSRPDAAFAEIQRT

USP17L18

21

D6R9N7
TSSRPDAAFAEIQRT

USP17L5

21

A8MUK1
TSSRPDAAFAEIQRT

USP17L21

21

D6R901
TSSRPDAAFAEIQRT

USP17L19

21

D6RCP7
RVRSAFAAPSTDSDQ

TBC1D3E

501

A0A087X179
SDRFSAERPEGSIST

TRBV7-7

81

A0A0K0K1E9
RNSAPVSVSAVRTSF

ARHGAP31

1176

Q2M1Z3
RDGSRLSASTVPLTF

RFPL3

221

O75679
TSSRPDAAFAEIQRT

USP17L1

21

Q7RTZ2
VRAEATTRSRESSPS

VCPIP1

986

Q96JH7
SQASFRISVPSSESR

PLEKHH1

501

Q9ULM0
AARPRSISESSASSA

SEC16B

861

Q96JE7
EAEASRSLESRSSRP

TINCR

101

A0A2R8Y7D0
TFTLERVSPSTSDLA

UNC5A

691

Q6ZN44
TSSRPDAAFAEIQRT

USP17L12

21

C9JPN9
FRASETSAFSRPVLS

TTC28

2206

Q96AY4
RSVETVSFSPDSRQL

WDR38

106

Q5JTN6
RATFVSSVRPESSRL

TPRN

636

Q4KMQ1
TSSRPDAAFAEIQRT

USP17L24

21

Q0WX57
PTFVRELRSRTFDSS

PHF8

121

Q9UPP1
RVRSAFAAPSTDSDQ

TBC1D3D

501

A0A087WVF3
STPELSRDVGRSVST

PLEKHG1

876

Q9ULL1
TSSRPDAAFAEIQRT

USP17L6P

21

Q6QN14
DVRESTAFSRSLLPV

XPC

146

Q01831
TSSRPDAAFAEIQRT

USP17L22

21

D6RA61
RTRRAASVAAATTSP

ZNF652

191

Q9Y2D9
RVRSAFAAPSTDSDQ

TBC1D3G

501

Q6DHY5
RVRSAFAAPSTDSDQ

TBC1D3

501

Q8IZP1
TSSRPDAAFAEIQRT

USP17L15

21

C9J2P7
TSSRPDAAFAEIQRT

USP17L17

21

D6RBQ6
RFSRSAIPEQIISST

POMZP3

16

Q6PJE2
AVAASFSPRSVSIRR

MST1R

206

Q04912
SATSRKSVREAASAP

TUB

221

P50607
RVRSAFAAPSTDSDQ

TBC1D3K

501

A0A087X1G2
TSSRPDAAFAEIQRT

USP17L23

21

D6RBM5
VSSVADSVASPLRES

TSHZ1

821

Q6ZSZ6
SRSNTEDFPLRLESA

TRBV6-9

86

A0A0J9YX75
TSSRPDAAFAEIQRT

USP17L2

21

Q6R6M4
TAVSSNRDPRTTAVS

nan

376

Q8N7P7
ISDSTSRRPSVFERL

ZC3H13

16

Q5T200
RVRSAFAAPSTDSDQ

TBC1D3I

501

A0A087WXS9
RVRSAFAAPSTDSDQ

TBC1D3C

501

Q6IPX1
SGRFSAERPERSVST

TRBV7-4

81

A0A1B0GX95
TSSRPDAAFAEIQRT

USP17L20

21

D6RJB6
SRSTTEDFPLRLLSA

TRBV6-5

86

A0A0K0K1A5
TSSRPDAAFAEIQRT

USP17L10

21

C9JJH3
TSSRPDAAFAEIQRT

USP17L11

21

C9JVI0
SAITPAAGRSRFSSV

KRT75

21

O95678
ASPASVRSLGRFSSV

KIAA1522

326

Q9P206
TGAALTPTEERRTSF

MYO9B

1341

Q13459