Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncholecystokinin receptor activity

CCKAR CCKBR

1.08e-052662GO:0004951
GeneOntologyMolecularFunctiontransporter activity

SLC6A2 CACNA1F ATP8A1 ATP11B TMC7 SLC13A1 SLC44A5 SLC24A2 KCNQ4 ABCC8 SLC44A2 ABCC11 SLC24A1 GRAMD1C SLC7A14

1.53e-0512896615GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A2 CACNA1F ATP8A1 ATP11B TMC7 SLC13A1 SLC44A5 SLC24A2 KCNQ4 ABCC8 SLC44A2 ABCC11 SLC24A1 SLC7A14

2.51e-0511806614GO:0022857
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A2 ATP8A1 SLC13A1 SLC44A5 SLC24A2 ABCC8 SLC44A2 ABCC11 SLC24A1

2.60e-05477669GO:0022804
GeneOntologyMolecularFunctionmannosyltransferase activity

DPY19L2 DPY19L4 DPY19L2P2

1.07e-0428663GO:0000030
GeneOntologyMolecularFunctioncalcium, potassium:sodium antiporter activity

SLC24A2 SLC24A1

1.07e-045662GO:0008273
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADORA2B TAS2R36 ABCC8 OR13F1 MC1R DNER OR2W5P GPRC6A SMIM17 IL1RL1 TEK IL5RA CCKAR CCKBR

1.11e-0413536614GO:0004888
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A2 CACNA1F ATP8A1 ATP11B TMC7 SLC13A1 SLC24A2 KCNQ4 ABCC8 SLC24A1

2.59e-047936610GO:0015075
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC44A5 SLC44A2

2.97e-048662GO:0015220
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP8A1 ATP11B

3.82e-049662GO:0090556
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A2 SLC13A1 SLC44A5 SLC24A2 SLC44A2 SLC24A1

4.35e-04296666GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A2 ATP8A1 SLC13A1 SLC24A2 ABCC8 SLC24A1

4.75e-04301666GO:0022853
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC24A2 SLC24A1

4.76e-0410662GO:0005432
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC24A2 SLC24A1

8.20e-0413662GO:0015368
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A2 CACNA1F SLC13A1 SLC24A2 KCNQ4 ABCC8 SLC24A1

8.45e-04465667GO:0046873
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP8A1 ATP11B

9.54e-0414662GO:0140333
GeneOntologyMolecularFunctionantiporter activity

SLC44A5 SLC24A2 SLC44A2 SLC24A1

1.13e-03138664GO:0015297
GeneOntologyMolecularFunctionfloppase activity

ATP8A1 ATP11B

1.25e-0316662GO:0140328
GeneOntologyMolecularFunctionflippase activity

ATP8A1 ATP11B

1.42e-0317662GO:0140327
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A2 CACNA1F ATP8A1 SLC13A1 SLC24A2 KCNQ4 ABCC8 SLC24A1

1.50e-03664668GO:0008324
GeneOntologyMolecularFunctionsymporter activity

SLC6A2 SLC13A1 SLC24A2 SLC24A1

1.54e-03150664GO:0015293
GeneOntologyMolecularFunctionadenylate cyclase activity

ADCY2 ADCY7

1.59e-0318662GO:0004016
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLC6A2 SLC44A2 ABCC11

1.61e-0370663GO:1901618
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A2 SLC13A1

1.77e-0319662GO:0015373
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC24A2 SLC24A1

1.77e-0319662GO:0022821
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC24A2 KCNQ4 ABCC8 SLC24A1

2.27e-03167664GO:0015079
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A2 SLC13A1 SLC24A2 SLC24A1

2.48e-03171664GO:0015081
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC6A2 SLC44A5 SLC44A2

2.62e-0383663GO:0015101
GeneOntologyMolecularFunctioncyclase activity

ADCY2 ADCY7

2.83e-0324662GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

ADCY2 ADCY7

3.07e-0325662GO:0016849
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A2 SLC13A1

3.32e-0326662GO:0015296
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A2 CACNA1F SLC13A1 SLC24A2 KCNQ4 ABCC8 ABCC11 SLC24A1

3.42e-03758668GO:0015318
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP8A1 ATP11B

3.85e-0328662GO:0140326
GeneOntologyMolecularFunctionlipid transporter activity

ATP8A1 ATP11B ABCC11 GRAMD1C

4.04e-03196664GO:0005319
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1F TMC7 SLC24A2 KCNQ4 ABCC8 SLC24A1

4.05e-03459666GO:0005216
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A2 CACNA1F SLC13A1 SLC24A2 KCNQ4 ABCC8 SLC24A1

4.56e-03627667GO:0022890
GeneOntologyMolecularFunctionhormone binding

MC1R CCKAR CCKBR

4.82e-03103663GO:0042562
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1F SLC24A2 KCNQ4 ABCC8 SLC24A1

5.51e-03343665GO:0005261
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP8A1 ABCC8 ABCC11

5.64e-03109663GO:0042626
GeneOntologyMolecularFunctionSNAP receptor activity

VAMP8 STX12

7.37e-0339662GO:0005484
GeneOntologyMolecularFunctionchannel activity

CACNA1F TMC7 SLC24A2 KCNQ4 ABCC8 SLC24A1

7.70e-03525666GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1F TMC7 SLC24A2 KCNQ4 ABCC8 SLC24A1

7.76e-03526666GO:0022803
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADORA2B TAS2R36 OR13F1 MC1R OR2W5P GPRC6A CCKAR CCKBR

8.47e-03884668GO:0004930
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC24A2 SLC24A1

8.90e-0343662GO:0140828
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1F SLC24A2 SLC24A1

8.96e-03129663GO:0005262
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

MC1R CCKAR CCKBR

9.74e-03133663GO:0008528
GeneOntologyBiologicalProcessprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

DPY19L2 DPY19L4 DPY19L2P2

6.22e-076663GO:0018406
GeneOntologyBiologicalProcesspeptidyl-tryptophan modification

DPY19L2 DPY19L4 DPY19L2P2

6.22e-076663GO:0018211
GeneOntologyBiologicalProcessprotein C-linked glycosylation

DPY19L2 DPY19L4 DPY19L2P2

6.22e-076663GO:0018103
GeneOntologyBiologicalProcessprotein C-linked glycosylation via tryptophan

DPY19L2 DPY19L4 DPY19L2P2

6.22e-076663GO:0018317
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CADM3 DCHS2 CADM1 CADM4 MPZL2 CDH19

2.96e-05187666GO:0007156
GeneOntologyBiologicalProcesscholecystokinin signaling pathway

CCKAR CCKBR

3.02e-053662GO:0038188
GeneOntologyBiologicalProcesspositive regulation of somatostatin secretion

CCKAR CCKBR

6.03e-054662GO:0090274
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

CADM3 DCHS2 CADM1 CADM4 SLITRK5 MPZL2 CDH19

6.27e-05313667GO:0098742
GeneOntologyBiologicalProcessprotein mannosylation

DPY19L2 DPY19L4 DPY19L2P2

6.84e-0525663GO:0035268
GeneOntologyBiologicalProcessmannosylation

DPY19L2 DPY19L4 DPY19L2P2

7.72e-0526663GO:0097502
GeneOntologyBiologicalProcessactivation of adenylate cyclase activity

ADORA2B ADCY2 ADCY7

1.74e-0434663GO:0007190
GeneOntologyBiologicalProcessregulation of somatostatin secretion

CCKAR CCKBR

2.10e-047662GO:0090273
GeneOntologyBiologicalProcesspositive regulation of adenylate cyclase activity

ADORA2B ADCY2 ADCY7

2.84e-0440663GO:0045762
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A2 GRAMD2A CACNA1F ATP8A1 ATP11B TMC7 SLC13A1 SLC24A2 KCNQ4 ABCC8 ABCC11 SLC24A1 CCKAR

3.56e-0413746613GO:0006811
GeneOntologyBiologicalProcessaminophospholipid transport

ATP8A1 ATP11B

3.58e-049662GO:0015917
GeneOntologyBiologicalProcesssomatostatin secretion

CCKAR CCKBR

3.58e-049662GO:0070253
GeneOntologyBiologicalProcesscholine transport

SLC44A5 SLC44A2

4.46e-0410662GO:0015871
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1F SLC24A2 SLC24A1

4.88e-0448663GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1F SLC24A2 SLC24A1

4.88e-0448663GO:1902656
GeneOntologyBiologicalProcesspositive regulation of cyclase activity

ADORA2B ADCY2 ADCY7

4.88e-0448663GO:0031281
GeneOntologyBiologicalProcesspositive regulation of lyase activity

ADORA2B ADCY2 ADCY7

5.19e-0449663GO:0051349
GeneOntologyBiologicalProcesscAMP biosynthetic process

ADCY2 ADCY7

5.44e-0411662GO:0006171
GeneOntologyBiologicalProcessERBB4 signaling pathway

CADM1 BTC

5.44e-0411662GO:0038130
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A2 CACNA1F ATP8A1 ATP11B TMC7 SLC13A1 SLC24A2 KCNQ4 ABCC8 ABCC11 SLC24A1

7.62e-0411156611GO:0034220
GeneOntologyBiologicalProcessrelaxation of smooth muscle

ADORA2B ABCC8

7.69e-0413662GO:0044557
GeneOntologyBiologicalProcessregulation of adenylate cyclase activity

ADORA2B ADCY2 ADCY7

8.95e-0459663GO:0045761
GeneOntologyBiologicalProcesspresynapse assembly

CADM1 SLITRK5 SLITRK6

9.40e-0460663GO:0099054
GeneOntologyBiologicalProcessorganic hydroxy compound transport

SLC6A2 ADORA2B SLC44A2 ABCC11 GRAMD1C STX12

9.92e-04358666GO:0015850
GeneOntologyCellularComponentnuclear inner membrane

DPY19L2 ATP11B DPY19L4 RNF13 DPY19L2P2

1.37e-0659685GO:0005637
GeneOntologyCellularComponentcell surface

SLC6A2 ADORA2B MFAP3 ADAM30 IL1RL1 SLITRK6 VAMP8 TEK SLC24A1 DCBLD2 IL5RA

8.58e-0411116811GO:0009986
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP8A1 ATP11B

9.25e-0414682GO:1990531
GeneOntologyCellularComponentazurophil granule membrane

ATP8A1 ATP11B VAMP8

9.40e-0459683GO:0035577
GeneOntologyCellularComponentvacuolar membrane

ATP8A1 ATP11B SLC44A2 ABCC11 RNF13 VAMP8 SLC7A14

1.28e-03507687GO:0005774
MousePhenomultiflagellated sperm

CADM1 DPY19L2 DPY19L2P2

1.35e-0514483MP:0009839
MousePhenoabnormal sperm individualization

DPY19L2 DPY19L2P2

6.90e-054482MP:0031372
DomainCholcskin_rcpt

CCKAR CCKBR

1.08e-052622IPR009126
DomainNeurexin-like

CADM3 CADM1 CADM4

1.24e-0514623IPR003585
Domain4.1m

CADM3 CADM1 CADM4

1.24e-0514623SM00294
DomainDpy19

DPY19L2 DPY19L4

6.48e-054622PF10034
DomainDpy-19/Dpy-19-like

DPY19L2 DPY19L4

6.48e-054622IPR018732
DomainK/Na/Ca-exchanger

SLC24A2 SLC24A1

1.08e-045622IPR004481
DomainCholine_transpo

SLC44A5 SLC44A2

1.08e-045622PF04515
DomainCholine_transptr-like

SLC44A5 SLC44A2

1.08e-045622IPR007603
DomainAdcy_conserved_dom

ADCY2 ADCY7

1.61e-046622IPR009398
DomainDUF1053

ADCY2 ADCY7

1.61e-046622PF06327
DomainIG_LIKE

CADM3 VSTM4 MFAP3 CADM1 CADM4 IL1RL1 MPZL2 TEK

2.10e-04491628PS50835
DomainIg-like_dom

CADM3 VSTM4 MFAP3 CADM1 CADM4 IL1RL1 MPZL2 TEK

2.47e-04503628IPR007110
DomainAC_N

ADCY2 ADCY7

3.00e-048622IPR032628
DomainAdcy

ADCY2 ADCY7

3.00e-048622IPR030672
DomainAC_N

ADCY2 ADCY7

3.00e-048622PF16214
Domain-

CADM3 VSTM4 MFAP3 CADM1 CADM4 IL1RL1 MPZL2 TEK IL5RA

3.20e-046636292.60.40.10
DomainC2-set_2

CADM3 CADM1 CADM4

3.39e-0441623PF08205
DomainCD80_C2-set

CADM3 CADM1 CADM4

3.39e-0441623IPR013162
DomainV-set

CADM3 VSTM4 CADM1 CADM4 MPZL2

3.61e-04184625PF07686
DomainNaCa_Exmemb

SLC24A2 SLC24A1

3.85e-049622IPR004837
DomainNa_Ca_ex

SLC24A2 SLC24A1

3.85e-049622PF01699
DomainIg_I-set

CADM3 MFAP3 CADM1 CADM4 IL1RL1

4.18e-04190625IPR013098
DomainI-set

CADM3 MFAP3 CADM1 CADM4 IL1RL1

4.18e-04190625PF07679
DomainIG

CADM3 VSTM4 MFAP3 CADM1 CADM4 IL1RL1 MPZL2

4.75e-04421627SM00409
DomainIg_sub

CADM3 VSTM4 MFAP3 CADM1 CADM4 IL1RL1 MPZL2

4.75e-04421627IPR003599
DomainIg-like_fold

CADM3 VSTM4 MFAP3 CADM1 CADM4 IL1RL1 MPZL2 TEK IL5RA

5.05e-04706629IPR013783
DomainIg_V-set

CADM3 VSTM4 CADM1 CADM4 MPZL2

5.16e-04199625IPR013106
DomainP_typ_ATPase_c

ATP8A1 ATP11B

9.62e-0414622IPR032630
DomainP-type_ATPase_N

ATP8A1 ATP11B

9.62e-0414622IPR032631
DomainP-type_ATPase_IV

ATP8A1 ATP11B

9.62e-0414622IPR006539
DomainPhoLip_ATPase_C

ATP8A1 ATP11B

9.62e-0414622PF16212
DomainPhoLip_ATPase_N

ATP8A1 ATP11B

9.62e-0414622PF16209
DomainIGc2

CADM3 MFAP3 CADM1 CADM4 IL1RL1

1.09e-03235625SM00408
DomainIg_sub2

CADM3 MFAP3 CADM1 CADM4 IL1RL1

1.09e-03235625IPR003598
DomainGRAM

GRAMD2A GRAMD1C

1.26e-0316622SM00568
DomainA/G_cyclase_CS

ADCY2 ADCY7

1.43e-0317622IPR018297
DomainNucleotide_cyclase

ADCY2 ADCY7

1.60e-0318622IPR029787
Domain-

ADCY2 ADCY7

1.60e-03186223.30.70.1230
DomainGUANYLATE_CYCLASE_2

ADCY2 ADCY7

1.79e-0319622PS50125
DomainGUANYLATE_CYCLASE_1

ADCY2 ADCY7

1.79e-0319622PS00452
DomainA/G_cyclase

ADCY2 ADCY7

1.79e-0319622IPR001054
DomainCYCc

ADCY2 ADCY7

1.79e-0319622SM00044
DomainGuanylate_cyc

ADCY2 ADCY7

1.79e-0319622PF00211
DomainGRAM

GRAMD2A GRAMD1C

2.40e-0322622PF02893
DomainGRAM

GRAMD2A GRAMD1C

2.40e-0322622IPR004182
DomainABC_membrane

ABCC8 ABCC11

2.85e-0324622PF00664
DomainABC_TM1F

ABCC8 ABCC11

3.88e-0328622PS50929
DomainABC1_TM_dom

ABCC8 ABCC11

3.88e-0328622IPR011527
Domain-

ATP8A1 ATP11B

5.04e-03326222.70.150.10
Domain-

ATP8A1 ATP11B

5.04e-03326223.40.1110.10
DomainATPase_P-typ_cyto_domN

ATP8A1 ATP11B

6.01e-0335622IPR023299
Domain7TM_GPCR_Srsx

ADORA2B MC1R CCKAR

6.14e-03112623SM01381
DomainATPase_P-typ_P_site

ATP8A1 ATP11B

6.35e-0336622IPR018303
DomainP_typ_ATPase

ATP8A1 ATP11B

6.35e-0336622IPR001757
DomainATPASE_E1_E2

ATP8A1 ATP11B

6.35e-0336622PS00154
DomainATPase_P-typ_transduc_dom_A

ATP8A1 ATP11B

6.70e-0337622IPR008250
DomainE1-E2_ATPase

ATP8A1 ATP11B

6.70e-0337622PF00122
DomainEGF_3

BTC DNER ADAM30 TEK

7.71e-03235624PS50026
DomainABC_transporter_CS

ABCC8 ABCC11

8.57e-0342622IPR017871
DomainEGF-like_dom

BTC DNER ADAM30 TEK

9.40e-03249624IPR000742
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A2 ATP8A1 ATP11B SLC13A1 SLC44A5 SLC24A2 SLC44A2 ABCC11 SLC24A1 ADCY2 ADCY7

5.46e-067364111M27287
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

ADORA2B CACNA1F ADCY2 ADCY7 CCKAR CCKBR

1.16e-05178416M2890
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A2 SLC13A1 SLC44A5 SLC24A2 SLC44A2 SLC24A1

5.96e-05238416MM15076
PathwayWP_PEPTIDE_GPCRS

ATP8A1 MC1R CCKAR CCKBR

6.45e-0575414M39696
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A2 SLC13A1 SLC44A5 SLC44A2

6.79e-0576414MM15072
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A2 SLC13A1 SLC44A5 SLC24A2 SLC44A2 SLC24A1

7.66e-05249416M5988
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A2 SLC13A1 SLC44A5 SLC44A2

1.00e-0484414M27334
PathwayKEGG_DILATED_CARDIOMYOPATHY

CACNA1F SGCD ADCY2 ADCY7

1.31e-0490414M835
PathwayREACTOME_NECTIN_NECL_TRANS_HETERODIMERIZATION

CADM3 CADM1

1.72e-047412M27333
PathwayREACTOME_NECTIN_NECL_TRANS_HETERODIMERIZATION

CADM3 CADM1

1.72e-047412MM15068
PathwayREACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION

ADORA2B ADCY2 ADCY7

2.60e-0443413M29837
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

ADORA2B CACNA1F ADCY2 ADCY7

3.37e-04115414M9387
PathwayREACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY

ADCY2 ADCY7

3.66e-0410412M19522
PathwayREACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY

ADCY2 ADCY7

3.66e-0410412MM14668
PathwayREACTOME_NEURONAL_SYSTEM

KCNQ4 ABCC8 SLITRK5 SLITRK6 ADCY2 ADCY7

3.84e-04335416MM14503
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC24A2 SLC24A1

4.46e-0411412M27336
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

CADM3 CADM1 CDH19

6.31e-0458413M11980
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC24A2 SLC24A1

6.31e-0413412MM15078
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A2 ATP8A1 ATP11B SLC13A1 SLC44A5 SLC24A2 SLC44A2 SLC24A1

6.59e-04681418MM14985
PathwayREACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY

ADCY2 ADCY7

7.35e-0414412MM14669
PathwayREACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY

ADCY2 ADCY7

7.35e-0414412M750
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

IER3 BTC IL1RL1 ADCY2 ADCY7

7.77e-04252415MM15585
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

ADCY2 ADCY7

8.46e-0415412M47794
PathwayPID_LPA4_PATHWAY

ADCY2 ADCY7

8.46e-0415412M56
PathwayKEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY

ADCY2 ADCY7

8.46e-0415412M47504
PathwayWP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE

ADCY2 ADCY7

9.65e-0416412M39849
PathwayKEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY

ADCY2 ADCY7

9.65e-0416412M47645
PathwayKEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY

ADCY2 ADCY7

9.65e-0416412M47650
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

ADCY2 ADCY7

9.65e-0416412MM14492
PathwayWP_GPCRS_NONODORANT

ADORA2B MC1R GPRC6A CCKAR CCKBR

9.91e-04266415MM15843
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

ADORA2B MC1R ADCY2 ADCY7

1.09e-03157414M4904
PathwayREACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING

ADCY2 ADCY7

1.09e-0317412M26995
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

ADCY2 ADCY7

1.09e-0317412M47544
PathwayWP_GPCRS_PEPTIDE

MC1R CCKAR CCKBR

1.09e-0370413MM15959
PathwayREACTOME_NEURONAL_SYSTEM

KCNQ4 ABCC8 SLITRK5 SLITRK6 ADCY2 ADCY7

1.12e-03411416M735
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

SLITRK5 SLITRK6

1.52e-0320412M27290
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

SLITRK5 SLITRK6

1.52e-0320412MM14991
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

ADCY2 ADCY7

1.52e-0320412M759
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADORA2B MC1R CCKAR CCKBR

2.03e-03186414MM15994
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

IER3 BTC IL1RL1 ADCY2 ADCY7

2.03e-03313415M27867
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ADCY2 ADCY7

2.19e-0324412M47520
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

CADM3 CADM1 CDH19

2.25e-0390413M820
PathwayREACTOME_SIGNALING_BY_GPCR

ADORA2B MC1R GPRC6A ADCY2 ADCY7 CCKAR CCKBR

2.37e-03646417MM14962
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

ADCY2 ADCY7

2.57e-0326412M47553
PathwayREACTOME_SYNTHESIS_OF_PC

SLC44A5 SLC44A2

2.57e-0326412MM14584
PathwayREACTOME_CA_DEPENDENT_EVENTS

ADCY2 ADCY7

2.57e-0326412MM14495
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ADCY2 ADCY7

2.77e-0327412M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ADCY2 ADCY7

2.77e-0327412M47519
PathwayREACTOME_SYNTHESIS_OF_PC

SLC44A5 SLC44A2

2.97e-0328412M684
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

ADCY2 ADCY7

2.97e-0328412M47647
PathwayKEGG_MELANOGENESIS

MC1R ADCY2 ADCY7

3.12e-03101413M7761
PathwayKEGG_GNRH_SIGNALING_PATHWAY

CACNA1F ADCY2 ADCY7

3.12e-03101413M1979
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ADCY2 ADCY7

3.19e-0329412M47515
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

ADCY2 ADCY7

3.19e-0329412M47627
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

MC1R ADCY2

3.41e-0330412M42578
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ADCY2 ADCY7

3.64e-0331412M47507
PathwayREACTOME_SIGNALING_BY_GPCR

ADORA2B MC1R GPRC6A ADCY2 ADCY7 CCKAR CCKBR

3.77e-03702417M746
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ABCC8 ADCY2 ADCY7

3.77e-03108413M17034
PathwayKEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY

ADCY2 ADCY7

3.87e-0332412M47506
PathwayREACTOME_G_ALPHA_Z_SIGNALLING_EVENTS

ADCY2 ADCY7

4.12e-0333412MM15058
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

ADCY2 ADCY7

4.12e-0333412M11575
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

IER3 BTC IL1RL1

4.28e-03113413MM14783
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

ADCY2 ADCY7

4.62e-0335412M47969
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

CADM3 CADM1 CDH19

4.72e-03117413M19248
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

IER3 BTC IL1RL1

4.83e-03118413M713
PathwayREACTOME_CA_DEPENDENT_EVENTS

ADCY2 ADCY7

5.15e-0337412M749
PathwayKEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT

VAMP8 STX12

5.43e-0338412M17857
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ADCY2 ADCY7

5.71e-0339412MM14496
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

CADM3 CADM1

6.00e-0340412MM15060
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ADCY2 ADCY7

6.30e-0341412M512
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

CADM3 CADM1

6.60e-0342412M39703
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

CADM3 CADM1

6.60e-0342412MM15822
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADORA2B MC1R CCKAR CCKBR

6.70e-03260414M39397
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

ADORA2B ADCY2 ADCY7

6.88e-03134413M29840
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

ADCY2 ADCY7

6.91e-0343412M933
PathwayREACTOME_GABA_B_RECEPTOR_ACTIVATION

ADCY2 ADCY7

6.91e-0343412M954
PathwayKEGG_ABC_TRANSPORTERS

ABCC8 ABCC11

7.23e-0344412M11911
PathwayREACTOME_GABA_B_RECEPTOR_ACTIVATION

ADCY2 ADCY7

7.23e-0344412MM15709
PathwayREACTOME_GPER1_SIGNALING

ADCY2 ADCY7

7.55e-0345412M45008
PathwayREACTOME_GPCR_LIGAND_BINDING

ADORA2B MC1R GPRC6A CCKAR CCKBR

7.83e-03430415MM15160
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

ADORA2B MC1R CCKAR CCKBR

7.84e-03272414M13380
PathwayWP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY

ADCY2 ADCY7

7.88e-0346412M39828
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

CADM3 CADM1

8.55e-0348412MM15069
PathwayREACTOME_G_ALPHA_Z_SIGNALLING_EVENTS

ADCY2 ADCY7

8.55e-0348412M10775
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

CCKAR CCKBR

9.26e-0350412M47951
PathwayREACTOME_AQUAPORIN_MEDIATED_TRANSPORT

ADCY2 ADCY7

9.98e-0352412M920
PathwayREACTOME_CELL_CELL_COMMUNICATION

CADM3 CADM1 CDH19

1.02e-02155413M522
Pubmed

Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons.

CADM3 CADM1 CADM4

2.86e-08468333397712
Pubmed

Bioinformatic characterization of the SynCAM family of immunoglobulin-like domain-containing adhesion molecules.

CADM3 CADM1 CADM4

2.86e-08468316311015
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

CADM3 VSTM4 MFAP3 CADM1 CADM4 MPZL2 TEK

3.19e-0816268725826454
Pubmed

Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy.

CADM3 CADM1 CADM4

7.13e-08568323825401
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

CADM3 CADM1 CADM4 SLITRK5 SLITRK6 DCBLD2

1.18e-0711768617145500
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

CADM3 DPY19L2 DNAJC10 ADAM30 EMP1 MPZL2 CDH19 DPY19L2P2 GRAMD1C

2.83e-0746068920562862
Pubmed

Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions.

CADM3 CADM1 CADM4

5.95e-07968318615557
Pubmed

Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

ADORA2B ABCC8 TEK CCKAR CCKBR

3.48e-0611768518996102
Pubmed

Anxiety-related behaviors in cholecystokinin-A, B, and AB receptor gene knockout mice in the plus-maze.

CCKAR CCKBR

3.77e-06268212459512
Pubmed

Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus.

DPY19L2 DPY19L2P2

3.77e-06268222764053
Pubmed

Absence of the cholecystokinin-A receptor deteriorates homeostasis of body temperature in response to changes in ambient temperature.

CCKAR CCKBR

3.77e-06268215178543
Pubmed

Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors.

CCKAR CCKBR

3.77e-06268225160855
Pubmed

Behavioral and cortical EEG evaluations confirm the roles of both CCKA and CCKB receptors in mouse CCK-induced anxiety.

CCKAR CCKBR

3.77e-06268223043971
Pubmed

[The expression of cholecystokinin-octapeptide receptor in vascular endothelial cells induced by lipopolysaccharide].

CCKAR CCKBR

3.77e-06268219751565
Pubmed

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.

CCKAR CCKBR

3.77e-06268239083706
Pubmed

Energy metabolism and turnover are increased in mice lacking the cholecystokinin-B receptor.

CCKAR CCKBR

3.77e-06268211925470
Pubmed

Responses of human sling and clasp fibers to cholecystokinin (CCK) and gastrin through CCK receptors.

CCKAR CCKBR

3.77e-06268218444993
Pubmed

Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins.

CADM3 CADM4

3.77e-06268211536053
Pubmed

Molecular cloning and functional expression of the potassium-dependent sodium-calcium exchanger from human and chicken retinal cone photoreceptors.

SLC24A2 SLC24A1

3.77e-06268210662833
Pubmed

Expression of cholecystokinin receptors in colon cancer and the clinical correlation in Taiwan.

CCKAR CCKBR

3.77e-06268226508021
Pubmed

Molecular cloning, functional expression and chromosomal localization of the human cholecystokinin type A receptor.

CCKAR CCKBR

3.77e-0626828343165
Pubmed

Functional compensation between cholecystokinin-1 and -2 receptors in murine paraventricular nucleus neurons.

CCKAR CCKBR

3.77e-06268223038256
Pubmed

The cell adhesion nectin-like molecules (Necl) 1 and 4 suppress the growth and tumorigenic ability of colon cancer cells.

CADM3 CADM4

3.77e-06268219565570
Pubmed

Structure and developmental expression of the mouse CCK-B receptor gene.

CCKAR CCKBR

3.77e-06268210860839
Pubmed

Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study.

CCKAR CCKBR

3.77e-06268227072272
Pubmed

The Role of Cholecystokinin in Peripheral Taste Signaling in Mice.

CCKAR CCKBR

3.77e-06268229163209
Pubmed

Gastric acid secretion in cholecystokinin-1 receptor, -2 receptor, and -1, -2 receptor gene knockout mice.

CCKAR CCKBR

3.77e-06268219340558
Pubmed

Variants Near CCK Receptors are Associated With Electrophysiological Responses to Pre-pulse Startle Stimuli in a Mexican American Cohort.

CCKAR CCKBR

3.77e-06268226608796
Pubmed

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.

DPY19L2 DPY19L2P2

3.77e-06268225354700
Pubmed

Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.

DPY19L2 DPY19L2P2

3.77e-06268225354701
Pubmed

Heterodimerization of type A and B cholecystokinin receptors enhance signaling and promote cell growth.

CCKAR CCKBR

3.77e-06268214534299
Pubmed

Distribution of CCK1 and CCK2 receptors in normal and diseased human pancreatic tissue.

CCKAR CCKBR

3.77e-06268212851875
Pubmed

Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.

CADM1 CADM4

3.77e-06268235213073
Pubmed

Enhanced gastric emptying of a liquid gastric load in mice lacking cholecystokinin-B receptor: a study of CCK-A,B, and AB receptor gene knockout mice.

CCKAR CCKBR

3.77e-06268215168241
Pubmed

Isolation of the mouse Tsll1 and Tsll2 genes, orthologues of the human TSLC1-like genes 1 and 2 (TSLL1 and TSLL2).

CADM3 CADM4

3.77e-06268214659875
Pubmed

Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex.

DPY19L2 DPY19L4 DPY19L2P2

7.96e-062068322028030
Pubmed

Association study of polymorphisms in cholecystokinin gene and its receptors with antipsychotic induced weight gain in schizophrenia patients.

CCKAR CCKBR

1.13e-05368220732371
Pubmed

Interhemispheric cortical long-term potentiation in the auditory cortex requires heterosynaptic activation of entorhinal projection.

CCKAR CCKBR

1.13e-05368237123227
Pubmed

Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope.

DPY19L2 DPY19L2P2

1.13e-05368225775128
Pubmed

Duplication and relocation of the functional DPY19L2 gene within low copy repeats.

DPY19L2 DPY19L2P2

1.13e-05368216526957
Pubmed

No association of CCK and CCK(B) receptor polymorphisms with alcohol dependence.

CCKAR CCKBR

1.13e-05368211368834
Pubmed

Genetic polymorphisms in Parkinson disease subjects with and without hallucinations: an analysis of the cholecystokinin system.

CCKAR CCKBR

1.13e-05368215313848
Pubmed

Cholecystokinin, cholecystokinin-A receptor and cholecystokinin-B receptor gene polymorphisms in Parkinson's disease.

CCKAR CCKBR

1.13e-05368212777967
Pubmed

Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.

CADM3 CADM1

1.13e-05368215741237
Pubmed

Cholecystokinin plays a novel protective role in diabetic kidney through anti-inflammatory actions on macrophage: anti-inflammatory effect of cholecystokinin.

CCKAR CCKBR

1.13e-05368222357963
Pubmed

Investigation of quantitative trait loci in the CCKAR gene with susceptibility to alcoholism.

CCKAR CCKBR

1.13e-05368212198366
Pubmed

Gene variations in the cholecystokinin system in patients with panic disorder.

CCKAR CCKBR

1.13e-05368220023595
Pubmed

Lack of ghrelin secretion in response to fasting in cholecystokinin-A (-1), -B (-2) receptor-deficient mice.

CCKAR CCKBR

1.13e-05368217134539
Pubmed

Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways.

CCKAR CCKBR

2.25e-05468226948890
Pubmed

Cation dependencies and turnover rates of the human K⁺-dependent Na⁺-Ca²⁺ exchangers NCKX1, NCKX2, NCKX3 and NCKX4.

SLC24A2 SLC24A1

2.25e-05468226631410
Pubmed

Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis.

SLC44A5 SLC44A2

2.25e-05468223651124
Pubmed

Chromosomal localization of the gastric and brain receptors for cholecystokinin (CCKAR and CCKBR) in human and mouse.

CCKAR CCKBR

2.25e-0546827759110
Pubmed

Expression of potassium-dependent sodium-calcium exchanger in the murine lens.

SLC24A2 SLC24A1

3.75e-05568229128492
Pubmed

FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice.

DPY19L2 DPY19L2P2

3.75e-05568234471926
Pubmed

Axoglial Adhesion by Cadm4 Regulates CNS Myelination.

CADM3 CADM4

3.75e-05568230551998
Pubmed

Molecular characterization of the family of choline transporter-like proteins and their splice variants.

SLC44A5 SLC44A2

3.75e-05568215715662
Pubmed

Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.

SLITRK5 SLITRK6

5.62e-05668214557068
Pubmed

Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells.

CCKAR CCKBR

5.62e-05668210536058
Pubmed

Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

SLITRK5 SLITRK6

5.62e-05668214550773
Pubmed

Sodium/calcium exchanger expression in the mouse and rat olfactory systems.

SLC24A2 SLC24A1

5.62e-05668217311327
Pubmed

Differential expression of Slitrk family members in the mouse nervous system.

SLITRK5 SLITRK6

5.62e-05668219924824
Pubmed

Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.

ADCY2 ADCY7

7.86e-05768238109525
Pubmed

Cholecystokinin modulates migration of gonadotropin-releasing hormone-1 neurons.

CCKAR CCKBR

1.05e-04868215152034
Pubmed

Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells.

CADM3 CADM1

1.05e-04868212826663
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

CADM1 CADM4 SLITRK6 MPZL2 VAMP8 DCBLD2 STX12

1.24e-0456968730639242
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

CADM3 CADM1 DPY19L2 DNAJC10 DNER ADAM30 MPZL2 CDH19 GRAMD1C

1.25e-0498568912975309
Pubmed

Genetical genomic determinants of alcohol consumption in rats and humans.

SLC6A2 ADCY7 CCKAR CCKBR

1.26e-0413068419874574
Pubmed

Identification of novel germline polymorphisms governing capecitabine sensitivity.

SLC44A5 ADCY2

1.34e-04968222864933
Pubmed

Role of the calcium modulated cyclases in the development of the retinal projections.

ADCY2 ADCY7

1.34e-04968217229090
Pubmed

Association testing of panic disorder candidate genes using CCK-4 challenge in healthy volunteers.

CCKAR CCKBR

1.34e-04968218832011
Pubmed

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.

ADCY2 ADCY7

1.34e-0496829417641
Pubmed

Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.

ADCY2 ADCY7

1.34e-04968212503609
Pubmed

Seven novel mammalian SNARE proteins localize to distinct membrane compartments.

VAMP8 STX12

1.34e-0496829553086
Pubmed

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.

ATP8A1 ATP11B

1.68e-041068215919184
Pubmed

Purification and characterization of a soluble form of mammalian adenylyl cyclase.

ADCY2 ADCY7

1.68e-04106828663304
Pubmed

Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.

ADCY2 ADCY7

1.68e-041068211884542
Pubmed

Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.

ADCY2 ADCY7

1.68e-041068216615126
Pubmed

Localization of the murine cholecystokinin A and B receptor genes.

CCKAR CCKBR

2.05e-04116827613026
Pubmed

Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.

ADCY2 ADCY7

2.05e-041168210089566
Pubmed

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner.

ATF6 SGCD

2.05e-041168238678560
Pubmed

gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.

ADCY2 ADCY7

2.05e-041168210808179
Pubmed

Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.

ADCY2 ADCY7

2.05e-041168211299302
Pubmed

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

ATP8A1 ATP11B

2.45e-041268221914794
Pubmed

Expression of adenylyl cyclase mRNAs in the denervated and in the developing mouse skeletal muscle.

ADCY2 ADCY7

2.45e-04126829611134
Pubmed

HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.

ADCY2 ADCY7

2.45e-041268210807185
Pubmed

Differential expression of putative transbilayer amphipath transporters.

ATP8A1 ATP11B

2.90e-041368211015572
Pubmed

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.

ADCY2 ADCY7

3.38e-041468214993377
Pubmed

Mechanism of GTP hydrolysis by G-protein alpha subunits.

ADCY2 ADCY7

3.89e-04156827937899
Pubmed

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes.

ADCY2 ADCY7

3.89e-04156822165385
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

ADCY2 ADCY7

4.44e-041668217567809
Pubmed

The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes.

VAMP8 STX12

4.44e-041668227791468
Pubmed

A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development.

SLITRK5 SLITRK6

5.03e-041768226102480
Pubmed

Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.

VAMP8 STX12

5.03e-041768214668490
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATF6 CADM1 DNAJC10 HS6ST2 MARCHF6 DNER DPY19L4 SLITRK5 DCBLD2

5.36e-04120168935696571
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

ABCC8 TEK CCKAR CCKBR

5.56e-0419268420602615
Pubmed

Disruption of Nectin-like 1 cell adhesion molecule leads to delayed axonal myelination in the CNS.

CADM3 CADM4

6.30e-041968219036974
Pubmed

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

ADORA2B DCHS2 ATP8A1

7.68e-049168322610502
Pubmed

Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.

SLITRK5 SLITRK6

8.48e-042268238736483
Pubmed

Stable association between G alpha(q) and phospholipase C beta 1 in living cells.

GPRC6A CCKAR CCKBR

8.70e-049568316754659
Pubmed

Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.

CCKAR CCKBR

9.28e-042368225875176
InteractionCCKAR interactions

CCKAR CCKBR

2.61e-053602int:CCKAR
InteractionSFTPC interactions

MFAP3 DNAJC10 HS6ST2 CADM4 MPZL2 DCBLD2

5.09e-05222606int:SFTPC
CytobandEnsembl 112 genes in cytogenetic band chr16q12

SLC6A2 ABCC11 ADCY7

4.73e-04103673chr16q12
Cytoband16q12.1

ABCC11 ADCY7

1.14e-033467216q12.1
GeneFamilyCholecystokinin receptors

CCKAR CCKBR

6.90e-062482224
GeneFamilyAdenosine receptors|V-set domain containing

CADM3 VSTM4 CADM1 CADM4 MPZL2

7.01e-05163485590
GeneFamilySolute carriers

SLC6A2 SLC13A1 SLC44A5 SLC24A2 SLC44A2 SLC24A1 SLC7A14

7.66e-05395487752
GeneFamilyImmunoglobulin like domain containing

CADM3 CADM1 CADM4 IL1RL1 TEK

1.55e-04193485594
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CADM3 CADM1 CADM4

1.62e-0440483592
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY2 ADCY7

3.06e-041048253
GeneFamilyATP binding cassette subfamily C

ABCC8 ABCC11

5.28e-0413482807
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

GRAMD2A GRAMD1C

5.28e-04134821146
GeneFamilyATPase phospholipid transporting

ATP8A1 ATP11B

7.09e-04154821210
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RL1 IL5RA

5.55e-0342482602
CoexpressionKIM_MYCN_AMPLIFICATION_TARGETS_DN

DNAJC10 ATP11B SLITRK6 SLC24A1 ADCY2

7.01e-06107655M2919
CoexpressionGSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP

ATP11B TMC7 HS6ST2 SLC44A2 SLITRK5 CCKAR

1.04e-05200656M7894
CoexpressionMASSARWEH_TAMOXIFEN_RESISTANCE_UP

SMIM13 ATP8A1 IER3 HS6ST2 DPY19L4 SLC44A2 EMP1 MPZL2 STX12

1.32e-05583659M17454
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC24A2 SGCD BTC CADM4 SLITRK6 CDH19

3.16e-1018765816e55d802fc4e71878305e61ad03806aabd59537
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC24A2 SGCD BTC CADM4 SLITRK6 CDH19

3.58e-10190658ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC24A2 SGCD BTC CADM4 SLITRK6 CDH19

3.58e-101906584971857eac9af17d66d673ed2ab7072639f60a10
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SGCD CADM4 DPY19L4 SLITRK6 CDH19

8.35e-09180657da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SGCD CADM4 DPY19L4 SLITRK6 CDH19

8.35e-091806575b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SGCD CADM4 DPY19L4 SLITRK6 CDH19

8.35e-0918065750758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19 SLC7A14

9.36e-09183657876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19 SLC7A14

9.36e-09183657b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19 SLC7A14

9.36e-091836578330c39184ce076e1f95fd3725b68af551d89db0
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

CADM3 CADM1 CADM4 SLITRK5 CDH19 SLC7A14

1.71e-0716865688c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

CADM3 CADM1 CADM4 SLITRK5 SLITRK6 CDH19

2.03e-071736566fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SGCD CADM4 SLITRK6 CDH19

2.40e-071786563e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19

2.56e-07180656d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19

2.56e-07180656dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

CADM3 CADM1 CADM4 SLITRK5 SLITRK6 CDH19

2.56e-071806565842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

CADM3 CADM1 CADM4 SLITRK5 SLITRK6 CDH19

2.65e-071816567d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19

2.73e-07182656812ff2a50a510b18d865e89465dba1754a08ef61
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 TMC7 CADM4 SLITRK6 CDH19

2.91e-071846569f8cd5ab5af6c35a1be25d70a125b9a3f4dd667a
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC24A2 CADM4 SLITRK6 CDH19

3.11e-07186656ea936e66ae4b7b40564711fad60ac0137327995f
ToppCelldroplet-Heart-HEART-1m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19

3.11e-07186656fddc6b93f98b10aaf8d4ebc142b46d8213f3129d
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC24A2 CADM4 SLITRK6 CDH19

3.21e-07187656a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC24A2 CADM4 SLITRK6 CDH19

3.21e-07187656f2af79a20438108c814a73f9e24cd986d537237f
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A2 CADM3 SLC44A5 ABCC8 DNER SLITRK5

3.31e-07188656bd091503f580dedab40e0996273101285d24b586
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM3 CTXND1 CADM4 SLITRK5 SLITRK6 CDH19

3.31e-07188656502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SGCD BTC HS6ST2 EMP1 SLITRK6 DCBLD2

3.31e-071886560e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCelldroplet-Heart-HEART-1m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19

3.41e-07189656a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6 CDH19

3.41e-071896564e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC6A2 SGCD BTC HS6ST2 EMP1 SLITRK6

4.22e-07196656ee45e4de9d706ec87094e87f47d3e514539b8092
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC6A2 SGCD BTC HS6ST2 EMP1 SLITRK6

4.22e-07196656fa4a85a3cd52df0da5dfedc0e584e9df8c61ce89
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC13A1 SLC24A2 IL1RL1 IL5RA ADCY7

1.50e-0613365581189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

CADM3 CADM1 SLITRK5 SLITRK6 CDH19

4.32e-061656556ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

CADM3 CTXND1 CADM1 SLITRK6 CDH19

4.71e-06168655c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

CADM3 CADM1 SLITRK5 SLITRK6 CDH19

4.85e-06169655a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CADM3 CTXND1 CADM4 SLITRK6 CDH19

5.29e-061726558d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRAMD2A CTXND1 CTXND2 CADM4 CDH19

5.44e-06173655789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRAMD2A CTXND1 CADM4 SLITRK5 CDH19

5.59e-06174655c9d4e375dedd2b099a9ed70ec38ff35bbb0ce48a
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRAMD2A CTXND1 CADM4 SLITRK5 CDH19

5.59e-061746551463c98f8f519dd030587abbdbeb1b4e1bca5dd1
ToppCell5'-GW_trimst-2-LymphNode-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRAMD2A CTXND1 CADM4 SLITRK5 CDH19

5.59e-06174655d421c0069d24cb560a3a429929e3cd1eceaeabcf
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTXND1 CADM1 TMC7 CADM4 CDH19

5.75e-06175655bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTXND1 CADM1 TMC7 CADM4 CDH19

5.75e-061756558b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTXND1 CADM1 TMC7 CADM4 CDH19

5.75e-061756550b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCell5'-Adult-SmallIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK6 CDH19

6.59e-061806555e6e38ee0758ef2342a6a821c78ed24b57bb7b11
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRAMD2A CADM1 CTXND2 CADM4 CDH19

6.59e-06180655b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell5'-Adult-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK6 CDH19

6.59e-06180655b88cd7ae922782176c057342d1b9eb9b8e5e7204
ToppCell5'-Adult-SmallIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK6 CDH19

6.59e-06180655ebd6e719a03f25155fa8181be19469d04d6d10a6
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CTXND2 CADM4 SLITRK6 CDH19

6.77e-06181655a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM1 HS6ST2 CADM4 CDH19 CTXN1

6.77e-06181655f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 BTC CADM4 CDH19

6.96e-06182655a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CADM4 SLITRK6 MPZL2 CTXN1

6.96e-061826556fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM3 CTXND1 SGCD CADM4 CDH19

6.96e-06182655a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CTXND1 ATP8A1 HS6ST2 CADM4 CDH19

7.14e-06183655f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 BTC CADM4 CDH19

7.53e-061856553d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 BTC CADM4 CDH19

7.53e-06185655995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 SLC44A5 CADM4 SLITRK5

7.53e-0618565511c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK6 CDH19

7.53e-06185655f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell5'-Adult-LargeIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK6 CDH19

7.53e-06185655317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK6 CDH19

7.53e-061856557bb8fdfe04f85d25056380ec58222366de323a21
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTXND1 CADM1 BTC CADM4 CDH19

7.73e-06186655d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK5 CDH19

7.73e-061866556f88b68735d0f7c9904eb8413e6007910d556185
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTXND1 SGCD CADM4 SLITRK6 CDH19

7.93e-061876556f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM3 CTXND1 CADM1 CADM4 SLITRK6

8.14e-06188655921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM1 ATP8A1 CADM4 CDH19 CTXN1

8.57e-061906555a82709eeb68df4563bb42b97636d110126d2f97
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DCHS2 SGCD DNER SLITRK5 EMP1

8.57e-061906554f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.01e-06192655ac507fd7cf3b3e521a15ef03bb4e81eb23807985
ToppCell3'-Child09-12-SmallIntestine-Neuronal|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.01e-0619265524f40dadec04f4f99c31000fa9f09d07148fa190
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A CADM1 ATP8A1 IER3 SLC44A2

9.01e-06192655790282d4232311df3dac4ad97c80fc53443beccc
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.01e-0619265571e04e197825856c6d4278fc76c58ab17ffa2387
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A CADM1 ATP8A1 IER3 SLC44A2

9.01e-06192655b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.48e-06194655d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.48e-06194655bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.48e-06194655408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell3'-Child04-06-SmallIntestine-Neuronal|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.72e-061956558d286622f86c844d1b06a106ee4a3f813eba05bb
ToppCell3'-Child04-06-SmallIntestine-Neuronal-Glial_mature|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.72e-061956554193e58788e90c3d1049ef5cf9800a8c4d8ac354
ToppCell15-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

CADM3 CADM1 CADM4 CDH19 SLC7A14

9.72e-0619565556356a9aeb67b50a74425be2cd9c50d31416c1b3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A2 CADM1 HS6ST2 DNER SLC7A14

9.72e-06195655a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell3'-Child04-06-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 SLITRK6 CDH19

9.72e-06195655359b9d791e26844675c3c60cf69d8ab69c2cf400
ToppCellEpithelial-Epithelial-A_(AT1)|Epithelial / shred on cell class and cell subclass (v4)

GRAMD2A CADM1 IER3 SLC44A2 TMEM140

9.96e-0619665541b21a18125cc95bc8adde3369e4abd029cf137d
ToppCell11.5-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

SLC44A5 ABCC8 MPZL2 VAMP8 ADCY2

9.96e-061966552648d64b0e7b59ae78182d55f32699ceea37ff8d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATP8A1 TMC7 SLC24A2 CDH19 SLC7A14

1.02e-0519765582b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 ABCC8 DNER SLC7A14

1.02e-05197655f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A2 CADM3 CADM1 ABCC8 SLC7A14

1.05e-0519865585881637641d8996be2edc65c4bceff0433135e7
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRAMD2A SLC24A2 SGCD DNER CDH19

1.05e-0519865502d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 CDH19 CTXN1

1.07e-05199655f2410509007d35e948a88f127f613d0119e6a4c4
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 DNER CDH19

1.07e-0519965547466253069d4b1b8f13ce3210f434e60753b38a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATP8A1 TMC7 SLC24A2 DNER CDH19

1.10e-05200655acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND1 CADM1 CADM4 SLITRK5 CDH19

1.10e-05200655363a8cebf2ace820661bcb87c7941f6671f8e5f3
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM3 CADM1 CADM4 CDH19 CTXN1

1.10e-0520065551d20543a9c9330c34c085d9290a1fc8b5bff0d4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 IER3 DNER EMP1 CTXN1

1.10e-05200655d9dab2aed11e45c60d11ff0c5af1f2fbb9cb45d8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CADM1 IER3 DNER EMP1 CTXN1

1.10e-0520065533b7af6c50e65dc1bdf429572574ed072f8bc29f
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A2 GDPD4 DCHS2 KCNQ4

1.64e-05104654b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A CADM1 ATP8A1 TSPAN16

3.93e-051306546434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

SGCD SMIM17 ADCY2 CCKAR

6.51e-05148654afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

SGCD SMIM17 ADCY2 CCKAR

6.51e-051486545f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CADM3 IER3 ABCC11 CTXN1

6.86e-05150654ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B KCNQ4 SLITRK5 IL1RL1

8.19e-05157654ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA2B KCNQ4 SLITRK5 IL1RL1

8.19e-05157654fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER3 HS6ST2 MC1R IL1RL1

8.19e-051576543c6be6995c00c4cadbd209c66bf9a87c8c238652
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER3 HS6ST2 MC1R IL1RL1

8.19e-05157654662d5026e0e4249029fc6f3abc771d775d7bc3bb
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CADM3 CADM1 BTC ADCY2

8.60e-05159654ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CADM3 CADM1 BTC ADCY2

8.60e-05159654b05fda31b77536a1878f55d3199563b53f9420b2
ComputationalNeighborhood of KDR

SLC6A2 VSTM4 SGCD CADM4 ABCC8

1.21e-0594355MORF_KDR
ComputationalNeighborhood of CD8A

SLC6A2 VSTM4 SGCD CADM4 ABCC8

5.01e-05126355MORF_CD8A
ComputationalNeighborhood of ITGA2

SLC6A2 VSTM4 CADM4

7.79e-0456353MORF_ITGA2
ComputationalNeighborhood of PTPRB

SLC6A2 VSTM4 SGCD CADM4 ABCC8

1.29e-03254355MORF_PTPRB
ComputationalNeighborhood of RAD51L3

SLC6A2 VSTM4 SGCD CADM4 ABCC8 MPZL2

1.40e-03387356MORF_RAD51L3
ComputationalNeighborhood of MAGEA8

SLC6A2 VSTM4 SGCD CADM4 ABCC8

1.43e-03260355MORF_MAGEA8
ComputationalGenes in the cancer module 162.

SLC6A2 SLC24A1

1.70e-0319352MODULE_162
ComputationalGenes in the cancer module 218.

SLC6A2 SLC24A1

1.89e-0320352MODULE_218
ComputationalNeighborhood of FSHR

SLC6A2 VSTM4 SGCD CADM4 ABCC8

1.95e-03279355MORF_FSHR
ComputationalNeighborhood of TNFRSF6

SLC6A2 VSTM4 CADM4 ABCC8

2.02e-03167354MORF_TNFRSF6
Drugcholecystokinin pentapeptide

CCKAR CCKBR

7.78e-062642ctd:C049128
DrugCholecystokinin

CCKAR CCKBR

7.78e-062642ctd:D002766
DrugFC28

CCKAR CCKBR

7.78e-062642CID000203398
DrugNN414

ABCC8 CCKAR CCKBR

1.16e-0516643CID000219048
DrugGastrin tetrapeptide

ADCY2 ADCY7 CCKAR CCKBR

1.19e-0550644CID000005415
DrugSKF 38393

ADORA2B GRINA ADCY2 ADCY7 CCKAR

1.46e-05110645CID000001242
Drugbaclofen

ADORA2B CACNA1F GPRC6A GRINA ADCY2 ADCY7

1.61e-05191646CID000002284
DrugJmv 332

CCKAR CCKBR

2.33e-053642CID006444167
DrugU-67827e

CCKAR CCKBR

2.33e-053642CID000128399
DrugPd 140376

CCKAR CCKBR

2.33e-053642CID000196935
DrugKsg 504

CCKAR CCKBR

2.33e-053642CID000132011
DrugAC1Q6XIX

CCKAR CCKBR

2.33e-053642CID000128819
Drugindole-2-carboxamide

CCKAR CCKBR

2.33e-053642CID000594832
Drugtebufenpyrad

CCKAR CCKBR

2.33e-053642CID000086354
DrugCBZ-cysteine

CCKAR CCKBR

2.33e-053642CID000097524
DrugWy-27587

CCKAR CCKBR

2.33e-053642CID000182584
Drugphenoxyacetylproglumide

CCKAR CCKBR

2.33e-053642CID000126961
DrugGBR 12935

SLC6A2 BTC MC1R

2.33e-0520643CID000003456
Drugmethylglucamine

SLC24A2 SLC24A1 CCKAR CCKBR

2.80e-0562644CID000004049
Drug12 B

SLC6A2 ATF6 CCKAR CCKBR

3.38e-0565644CID000067222
Drugpropylthiouracil

CADM3 CADM1 SLC13A1 CADM4 MPZL2

3.92e-05135645CID000657298
DrugTL-99

SGCD ADCY2 ADCY7

4.11e-0524643CID000122132
DrugL-368,935

CCKAR CCKBR

4.65e-054642CID000197533
DrugpBC 264

CCKAR CCKBR

4.65e-054642CID005491702
Drug4-NA

SLC24A2 SLC24A1

4.65e-054642CID006102690
Druggallogen

CCKAR CCKBR

4.65e-054642CID000021853
Drughippeastrine

ABCC8 ABCC11

4.65e-054642CID000441594
DrugSnf 8702

CCKAR CCKBR

4.65e-054642CID000131086
DrugMAPN

CCKAR CCKBR

4.65e-054642CID000151286
DrugGB-115

CCKAR CCKBR

4.65e-054642CID000060130
DrugPD 81,723

ADORA2B ADCY2 ADCY7

4.66e-0525643CID000122028
Drugbudipine

ADORA2B BTC GRINA

4.66e-0525643CID000068778
Drugi-Pr

DNER EMP1 ADCY2 ADCY7

5.34e-0573644CID000448400
DrugPeptavlon

ADCY2 ADCY7 CCKAR CCKBR

6.93e-0578644CID000021701
DrugMCI-727

CCKAR CCKBR

7.74e-055642CID006336097
DrugA 70874

CCKAR CCKBR

7.74e-055642CID006439313
DrugCR 1392

CCKAR CCKBR

7.74e-055642CID000065852
DrugDes(SO3)cck-8

CCKAR CCKBR

7.74e-055642CID003084441
DrugA-65186

CCKAR CCKBR

7.74e-055642CID003081191
DrugAC1Q6XJ0

CCKAR CCKBR

7.74e-055642CID000124911
DrugT-0632

CCKAR CCKBR

7.74e-055642CID000127948
Drug8-sulfocholecystokinin octapeptide

CCKAR CCKBR

7.74e-055642ctd:C090019
Drughexaethyl tetraphosphate

BTC DNER

7.74e-055642CID000012960
DrugAC1Q5XGY

CCKAR CCKBR

7.74e-055642CID000041315
Drugbrimonidine

ADORA2B SGCD ADCY2 ADCY7

1.01e-0486644CID000002435
DrugNSC755875

GRINA ADCY2 ADCY7 CCKAR CCKBR

1.02e-04165645CID000002215
Drugpropan

BTC DNER EMP1

1.09e-0433643CID000006334
DrugBMY 14802

GRINA CCKAR CCKBR

1.09e-0433643CID000108046
Drugphosphonate analog

CADM1 ADCY2 ADCY7

1.09e-0433643CID000475766
Drug2-oxopiperazine

MC1R CCKBR

1.16e-046642CID000231360
Druglauryl methacrylate

CCKAR CCKBR

1.16e-046642CID000008906
DrugA-71378

CCKAR CCKBR

1.16e-046642CID006918156
DrugCCK-6

CCKAR CCKBR

1.16e-046642CID003082185
DrugBoc-cck7

CCKAR CCKBR

1.16e-046642CID003082175
DrugBtlasp-NH2

CCKAR CCKBR

1.16e-046642CID000152221
DrugL-365,031

CCKAR CCKBR

1.16e-046642CID000196641
DrugLY288513

CCKAR CCKBR

1.16e-046642CID000132190
DrugAC1MMLID

TSPAN16 SLC24A2 KCNQ4 SLC24A1

1.32e-0492644CID000013245
DrugFG 7142

EMP1 CCKAR CCKBR

1.42e-0436643CID000004375
Drugamphetamine

SLC6A2 BTC GRINA ADCY2 ADCY7 CCKBR

1.46e-04284646CID000003007
DrugAC1NDT8A

SLC24A2 VAMP8 SLC24A1

1.54e-0437643CID004631218
Drugmagnesium nitrate

BTC DNER

1.62e-047642CID000025052
Drugboron carbide

DNER EMP1

1.62e-047642CID000123279
DrugJmv 320

CCKAR CCKBR

1.62e-047642CID003081775
DrugAC1L1XPX

BTC ADCY2 ADCY7

1.67e-0438643CID000011606
DrugD-myo-inositol-1,4,5-triphosphate

ADORA2B CACNA1F BTC MARCHF6 ADCY2 ADCY7 CCKAR CCKBR

1.85e-04568648CID000000806
Drugdesipramine

SLC6A2 ADORA2B BTC ADCY2 ADCY7

1.87e-04188645CID000002995
Drugdiazepam

ADORA2B GRINA ADCY2 ADCY7 CCKBR

1.92e-04189645CID000003016
Drugnoradrealine

SLC6A2 ADORA2B CACNA1F SGCD ABCC8 ABCC11 ADCY2 ADCY7

2.01e-04575648CID000000951
DrugNSC759576

CACNA1F SGCD DNER ADCY2 ADCY7

2.01e-04191645CID000003075
Drugguanosine 3',5'-cyclic monophosphoric acid

ADORA2B CACNA1F SLC24A2 ABCC11 GRINA SLC24A1 ADCY2 ADCY7

2.06e-04577648CID000000295
DrugN-nitrosobis(2-oxopropyl)amine

CADM1 CCKAR CCKBR

2.09e-0441643CID000043371
Drugspiroglumide

CCKAR CCKBR

2.15e-048642CID000065987
DrugRTI-121

SLC6A2 BTC

2.15e-048642CID000122190
DrugAC1L1GIZ

SLC6A2 BTC

2.15e-048642CID000003703
DrugRc 3100

CCKAR CCKBR

2.15e-048642CID005487260
DrugJmv 170

CCKAR CCKBR

2.15e-048642CID000196737
DrugJmv 179

CCKAR CCKBR

2.15e-048642CID000164107
DrugAC1L6VJ8

CCKAR CCKBR

2.15e-048642CID000300088
Drugnarciclasine

ABCC8 ABCC11

2.15e-048642CID000072376
Druggastrin 17

IER3 CCKBR

2.15e-048642ctd:C013550
DrugBenzocaine [94-09-7]; Up 200; 24.2uM; PC3; HT_HG-U133A

SGCD KCNQ4 CADM4 MS4A12 IL5RA

2.16e-041946454224_UP
DrugPrednicarbate [73771-04-7]; Up 200; 8.2uM; PC3; HT_HG-U133A

CADM3 IL1RL1 SLC24A1 GRAMD1C CCKAR

2.22e-041956455119_UP
DrugEthacrynic acid [58-54-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A

SLC6A2 ADAM30 SLC24A1 DCBLD2 IL5RA

2.22e-041956453181_UP
DrugNaringenine [480-41-1]; Up 200; 14.6uM; PC3; HT_HG-U133A

CADM3 CADM1 SGCD MPZL2 SLC24A1

2.27e-041966454597_UP
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A

SLC6A2 SGCD CADM4 SLC24A1 DCBLD2

2.27e-041966456061_UP
Drugestradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

CADM3 MFAP3 CADM4 SLC24A1 GRAMD1C

2.32e-041976455905_DN
DrugDihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A

ATP8A1 SGCD TEK SLC24A1 TMEM140

2.32e-041976454152_UP
DrugHeliotrine [303-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A

CADM3 ATP8A1 SGCD MARCHF6 DCBLD2

2.32e-041976453717_UP
DrugNatamycin [7681-93-8]; Up 200; 6uM; HL60; HT_HG-U133A

SLC6A2 SGCD IL1RL1 EMP1 IL5RA

2.32e-041976456126_UP
DrugDiltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A

SLC24A2 MARCHF6 SLC24A1 IL5RA ADCY7

2.32e-041976451532_UP
DrugAC1L9NAZ

ADORA2B TSPAN16 MC1R CCKAR CCKBR

2.38e-04198645CID000449606
DrugHarmane hydrochloride [21655-84-5]; Up 200; 18.2uM; HL60; HT_HG-U133A

MFAP3 TMC7 MARCHF6 SLC24A1 STX12

2.38e-041986452150_UP
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A

MFAP3 MARCHF6 GRINA SLC24A1 GRAMD1C

2.38e-041986453286_UP
DrugClomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; PC3; HT_HG-U133A

DCHS2 CADM1 CADM4 MARCHF6 CCKAR

2.38e-041986456648_UP
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; HL60; HT_HG-U133A

DCHS2 SGCD KCNQ4 DCBLD2 TMEM140

2.38e-041986453033_UP
DrugDimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A

CADM3 MFAP3 SGCD IL1RL1 SLC24A1

2.38e-041986456520_UP
DrugIohexol [66108-95-0]; Up 200; 4.8uM; HL60; HT_HG-U133A

MFAP3 SLC13A1 BTC IL5RA TMEM140

2.43e-041996452461_UP
DrugZalcitabine [7481-89-2]; Up 200; 19uM; PC3; HT_HG-U133A

SGCD CADM4 TEK IL5RA CCKAR

2.43e-041996454215_UP
DrugThalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A

CADM1 SLC13A1 SLITRK5 EMP1 CCKAR

2.43e-041996452095_UP
DiseaseObsessive-Compulsive Disorder

SLITRK5 CCKBR

7.13e-056652C0028768
Diseasepancreatic cancer (biomarker_via_orthology)

CCKAR CCKBR

9.96e-057652DOID:1793 (biomarker_via_orthology)
DiseaseUnipolar Depression

SLC6A2 CADM1 EMP1 ADCY7 CCKAR

2.69e-04259655C0041696
DiseaseX-Linked Csnb

CACNA1F SLC24A1

3.11e-0412652C3711543
DiseaseNight blindness, congenital stationary, type 1

CACNA1F SLC24A1

3.11e-0412652C3501847
DiseaseNight Blindness, Congenital Stationary, Type 1A

CACNA1F SLC24A1

3.11e-0412652C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

CACNA1F SLC24A1

3.11e-0412652C1864877
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

CACNA1F SLC24A1

3.11e-0412652C1848172
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

CACNA1F SLC24A1

3.11e-0412652C1850362
DiseaseCone-rod synaptic disorder, congenital nonprogressive

CACNA1F SLC24A1

3.67e-0413652C4041558
DiseaseNight blindness, congenital stationary

CACNA1F SLC24A1

6.36e-0417652C0339535
Diseasesensorineural hearing loss (implicated_via_orthology)

SLITRK6 SLC7A14

7.98e-0419652DOID:10003 (implicated_via_orthology)
Diseaseblood rubidium measurement

SGCD TEK

1.50e-0326652EFO_0021529
DiseaseCone-Rod Dystrophy 2

CACNA1F ATF6

1.87e-0329652C3489532
DiseaseStrabismus

SGCD ABCC11

1.87e-0329652HP_0000486
DiseaseMajor Depressive Disorder

SLC6A2 EMP1 ADCY7 CCKAR

2.05e-03243654C1269683

Protein segments in the cluster

PeptideGeneStartEntry
MIVLICVIVFIIILF

VAMP8

76

Q9BV40
TLIVVMSIFVLLLVL

GRAMD1C

556

Q8IYS0
MIINLILIVVCLFCL

ERVK-18

526

O42043
LIMLVIYIKIFLVAC

ADORA2B

196

P29275
RRVVCVMIVLAFIIL

ATF6

376

P18850
VIRMLIVIVVLFFLC

CCKAR

311

P32238
SLIFVCILLVHVLLM

ADCY7

601

P51828
IVAFIVFLLLIMLIF

CADM3

336

Q8N126
VVRMLLVIVVLFFLC

CCKBR

331

P32239
VFAFVLCLLVVLVLL

CTXN1

31

P60606
CFVFLCLFLVVMIIR

CTXND1

21

A0A1B0GTU2
VQILILFCILIAMSL

ATP8A1

296

Q9Y2Q0
VAVLLCLVVFFLAML

MC1R

186

Q01726
MLCAFLIINLFVAVI

CACNA1F

1426

O60840
AFMILSIIFCVIALL

EMP1

66

P54849
LLFLLLTIVFCQILM

IER3

86

P46695
LLVSMVVLFIFAILC

GRINA

286

Q7Z429
LFCAIVLLFLMLLFV

SLC24A1

1041

O60721
CLLILEFVMIVVFGL

KCNQ4

131

P56696
ILFAVILIFCILTLV

OR2W5P

26

A6NFC9
VVLLFLFLIVMIFRC

CTXND2

21

A0A1B0GV90
FLVLSLMVIAVLLIV

ABCC11

941

Q96J66
LRIFLLIVFMCITLL

MARCHF6

631

O60337
LIVFMCITLLIASLI

MARCHF6

636

O60337
ACALMIIIVIVVVLF

MPZL2

161

O60487
LILLVILLCVILMFI

GDPD4

71

Q6W3E5
LLLPVVMVITCFIFK

DPY19L2

496

Q6NUT2
YMIVCLIAFTITLIL

MFAP3

151

P55082
SFLVFLILICILIVM

DCHS2

3001

Q6V1P9
MAFLIILITCFVIIL

GPRC6A

1

Q5T6X5
VAVVVFAMLCLLIIL

CADM1

381

Q9BY67
MILLVNLFVLLSVVC

FAM189A2

1

Q15884
LIVFLLLIVMGSCLA

ADCY2

46

Q08462
IIMFRLILLILSVVF

ADAM30

691

Q9UKF2
CSVFLMLINVLVIIL

IL1RL1

336

Q01638
VIMATICFILLILSL

IL5RA

346

Q01344
ALLVFLIICVLVGMV

CADM4

331

Q8NFZ8
ILVLIICFLSMLQVI

DPY19L4

426

Q7Z388
LALVMLFLFAVIVLQ

HS6ST2

156

Q96MM7
LAFMIILSILEVIII

SLC44A2

316

Q8IWA5
FTFMIILCIIEVIVI

SLC44A5

326

Q8NCS7
ILCIIEVIVILMLIF

SLC44A5

331

Q8NCS7
VLVMVLTTLILILVC

DCBLD2

536

Q96PD2
RIILCFLIVYMAILV

DNAJC10

16

Q8IXB1
RLLKVFFVLICFLVM

GRAMD2A

311

Q8IUY3
VICLIAVMVVFIILV

BTC

121

P35070
IIIGALCVAFILMLI

DNER

641

Q8NFT8
LCVAFILMLIILIVG

DNER

646

Q8NFT8
QEIVTLVLFIIMALL

SLC13A1

346

Q9BZW2
EVIIAILICIMIIFG

CDH19

596

Q9H159
ILICIMIIFGFIFLT

CDH19

601

Q9H159
LLLPVVMVITCFIFK

DPY19L2P2

306

Q6ZN68
IIFAVCLLMYLITLL

OR13F1

26

Q8NGS4
LAFIGVILLLVDMCI

MS4A12

171

Q9NXJ0
MICFLLIILSILVVF

TAS2R36

1

P0DTE0
QLLLCLMVVVIVLYF

SLC6A2

236

P23975
ILGLLIMFITIVFCA

SLITRK6

611

Q9H5Y7
SIIVLVIVVICLMFY

TMEM140

16

Q9NV12
AIVLLFIMLLFVILS

SLC24A2

606

Q9UI40
FIMLLFVILSIALCK

SLC24A2

611

Q9UI40
VGICLILIVIFMITK

RNF13

191

O43567
VFVATLLIVLLLMVC

SMIM13

11

P0DJ93
IVLVVCVLFLFLVLT

SMIM17

96

P0DL12
ILTFMLLFVLVCEIA

ABCC8

76

Q09428
IILMVVTCLFLDIIK

ATP11B

1076

Q9Y2G3
TICVLLLFILMFIFC

SLC7A14

566

Q8TBB6
TRLLATIVMLLCFIF

SFT2D1

96

Q8WV19
TLLFCILSMVIVLIM

TSPAN16

86

Q9UKR8
LILSLLLVFIMSVFV

SLITRK5

666

O94991
FFVLLLMILILVNLA

SGCD

36

Q92629
MCILVLVLSVIILIL

STX12

251

Q86Y82
GMTCLTVLLAFLIIL

TEK

756

Q02763
CVGILSILLFMLVIV

VSTM4

186

Q8IW00
VLLNLVIFLIIFMLV

TMC7

171

Q7Z402