Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	axonogenesis	EPHB3 SEMA4F ROBO4 PLEKHG4 SPART PLXNB2 HOXA2 DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 CDK5R2 PLXNB3	2.87e-06	566	164	17	GO:0007409
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	EPHB3 SEMA4F ROBO4 LZTS3 PLEKHG4 FAT3 SPART PLXNB2 HOXA2 DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 CDK5R2 PLXNB3	8.24e-06	748	164	19	GO:0048667
GeneOntologyBiologicalProcess	axon development	EPHB3 SEMA4F ROBO4 PLEKHG4 SPART PLXNB2 HOXA2 DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 CDK5R2 PLXNB3	1.49e-05	642	164	17	GO:0061564
GeneOntologyBiologicalProcess	axon guidance	EPHB3 SEMA4F ROBO4 PLEKHG4 HOXA2 HMCN2 FEZF1 GLI3 SLIT3 NTN1 CDK5R2	1.83e-05	285	164	11	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	EPHB3 SEMA4F ROBO4 PLEKHG4 HOXA2 HMCN2 FEZF1 GLI3 SLIT3 NTN1 CDK5R2	1.89e-05	286	164	11	GO:0097485
GeneOntologyBiologicalProcess	neuron projection morphogenesis	EPHB3 SEMA4F ROBO4 LZTS3 PLEKHG4 SPART PLXNB2 HOXA2 DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 WASF1 CDK5R2 PLXNB3	2.18e-05	802	164	19	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	EPHB3 SEMA4F ROBO4 LZTS3 PLEKHG4 SPART PLXNB2 HOXA2 DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 WASF1 CDK5R2 PLXNB3	2.90e-05	819	164	19	GO:0120039
GeneOntologyBiologicalProcess	neuron projection development	EPHB3 NDNF SEMA4F ROBO4 LZTS3 PLEKHG4 FAT3 SPART FRYL PLXNB2 HOXA2 LIF MRTFB DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 LRRC7 WASF1 CDK5R2 PLXNB3	2.94e-05	1285	164	25	GO:0031175
GeneOntologyBiologicalProcess	cell projection morphogenesis	EPHB3 SEMA4F ROBO4 LZTS3 PLEKHG4 SPART PLXNB2 HOXA2 DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 WASF1 CDK5R2 PLXNB3	3.26e-05	826	164	19	GO:0048858
GeneOntologyBiologicalProcess	cell morphogenesis	EPHB3 SEMA4F ROBO4 LZTS3 PLEKHG4 FAT3 GATA1 SPART FRYL PLXNB2 HOXA2 LIF DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 WASF1 CDK5R2 PLXNB3	7.38e-05	1194	164	23	GO:0000902
GeneOntologyBiologicalProcess	neuron development	EPHB3 NDNF SEMA4F ROBO4 LZTS3 PLEKHG4 HCN1 FAT3 SPART FRYL PLXNB2 HOXA2 LIF MRTFB DST HMCN2 SNAP91 FEZF1 GLI3 TNN SLIT3 NTN1 LRRC7 WASF1 CDK5R2 PLXNB3	9.10e-05	1463	164	26	GO:0048666
HumanPheno	Perifollicular hyperkeratosis	KRT81 KRT83 KRT86	3.12e-06	4	48	3	HP:0007468
HumanPheno	Abnormal perifollicular morphology	KRT81 KRT83 KRT86	1.54e-05	6	48	3	HP:0031285
HumanPheno	Abnormal stool urobilinogen concentration	GATA1 UROS	8.70e-05	2	48	2	HP:0500114
HumanPheno	Increased stool urobilinogen concentration	GATA1 UROS	8.70e-05	2	48	2	HP:0500115
HumanPheno	Increased fecal coproporphyrin 1	GATA1 UROS	8.70e-05	2	48	2	HP:0033009
Domain	FN3	EPHB3 NDNF ROBO4 FNDC3B FNDC3A LEPR FNDC7 TNN EGFLAM	3.65e-05	185	163	9	SM00060
Domain	Ig-like_fold	EPHB3 NDNF ROBO4 FNDC3B FNDC3A PLXNB2 LEPR JAM2 MST1R VSTM4 FNDC7 HMCN2 HMCN1 TNN EGFLAM SIGLEC1 MADCAM1 PLXNB3	4.63e-05	706	163	18	IPR013783
Domain	FN3	EPHB3 NDNF ROBO4 FNDC3B FNDC3A LEPR FNDC7 TNN EGFLAM	6.43e-05	199	163	9	PS50853
Domain	-	EPHB3 NDNF ROBO4 FNDC3B FNDC3A PLXNB2 LEPR JAM2 MST1R VSTM4 FNDC7 HMCN1 TNN EGFLAM SIGLEC1 MADCAM1 PLXNB3	7.10e-05	663	163	17	2.60.40.10
Domain	RAI2/SOBP	SOBP RAI2	7.57e-05	2	163	2	IPR026092
Domain	SOBP	SOBP RAI2	7.57e-05	2	163	2	PF15279
Domain	FN3_dom	EPHB3 NDNF ROBO4 FNDC3B FNDC3A LEPR FNDC7 TNN EGFLAM	9.37e-05	209	163	9	IPR003961
Domain	Semap_dom	SEMA4F PLXNB2 MST1R PLXNB3	1.46e-04	31	163	4	IPR001627
Domain	SEMA	SEMA4F PLXNB2 MST1R PLXNB3	1.46e-04	31	163	4	PS51004
Domain	Sema	SEMA4F PLXNB2 MST1R PLXNB3	1.46e-04	31	163	4	SM00630
Domain	Sema	SEMA4F PLXNB2 MST1R PLXNB3	1.46e-04	31	163	4	PF01403
Domain	Plexin_repeat	SEMA4F PLXNB2 MST1R PLXNB3	1.66e-04	32	163	4	IPR002165
Domain	PSI	SEMA4F PLXNB2 MST1R PLXNB3	1.66e-04	32	163	4	PF01437
Domain	-	SEMA4F VPS11 GEMIN5 PLXNB2 ARHGEF10L MST1R GTF3C2 RPTOR DCAF11 CORO7 PLXNB3	1.69e-04	333	163	11	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA4F VPS11 GEMIN5 PLXNB2 ARHGEF10L MST1R GTF3C2 RPTOR DCAF11 CORO7 PLXNB3	1.78e-04	335	163	11	IPR015943
Domain	G2F	HMCN2 HMCN1	4.49e-04	4	163	2	PF07474
Domain	Tensin_PTB	TNS2 TNS3	4.49e-04	4	163	2	IPR033929
Domain	DDT	BPTF BAZ2A	4.49e-04	4	163	2	PF02791
Domain	NIDOGEN_G2	HMCN2 HMCN1	4.49e-04	4	163	2	PS50993
Domain	GFP	HMCN2 HMCN1	4.49e-04	4	163	2	IPR009017
Domain	G2_nidogen/fibulin_G2F	HMCN2 HMCN1	4.49e-04	4	163	2	IPR006605
Domain	fn3	EPHB3 ROBO4 FNDC3B FNDC3A FNDC7 TNN EGFLAM	5.57e-04	162	163	7	PF00041
Domain	PSI	SEMA4F PLXNB2 MST1R PLXNB3	5.78e-04	44	163	4	IPR016201
Domain	PSI	SEMA4F PLXNB2 MST1R PLXNB3	6.86e-04	46	163	4	SM00423
Domain	DDT	BPTF BAZ2A	7.44e-04	5	163	2	SM00571
Domain	DDT_dom	BPTF BAZ2A	7.44e-04	5	163	2	IPR018501
Domain	WHIM1_dom	BPTF BAZ2A	7.44e-04	5	163	2	IPR028942
Domain	WHIM2_dom	BPTF BAZ2A	7.44e-04	5	163	2	IPR028941
Domain	WSD	BPTF BAZ2A	7.44e-04	5	163	2	PF15613
Domain	WHIM1	BPTF BAZ2A	7.44e-04	5	163	2	PF15612
Domain	DDT	BPTF BAZ2A	1.11e-03	6	163	2	PS50827
Domain	Keratin_2_head	KRT81 KRT83 KRT86	1.15e-03	24	163	3	IPR032444
Domain	Keratin_2_head	KRT81 KRT83 KRT86	1.15e-03	24	163	3	PF16208
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F PPRC1 SHISA5 INTS1 C19orf47 C15orf39 GEMIN5 FRYL SRCAP PLXNB2 ARHGEF10L SBNO2 KANSL3 PIKFYVE MST1R KMT2C DST KLF10 ADAMTSL5 RPTOR EIF2B3 ANKRD11 ARHGAP21	3.81e-09	1105	167	23	35748872
Pubmed	Novel KRT83 and KRT86 mutations associated with monilethrix.	KRT81 KRT83 KRT86	1.09e-07	3	167	3	25557232
Pubmed	Identification of diabetes susceptibility loci in db mice by combined quantitative trait loci analysis and haplotype mapping.	LEPR TXNDC11 MRTFB	1.09e-07	3	167	3	16919419
Pubmed	Structure and site of expression of a murine type II hair keratin.	KRT81 KRT83 KRT86	1.09e-07	3	167	3	1372089
Pubmed	Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.	KRT81 KRT83 KRT86	1.09e-07	3	167	3	1712823
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	SEMA4F RGL3 C15orf39 PIKFYVE KMT2C MAP7D1 DST FEZF1 GLI3 TNS3	2.12e-07	233	167	10	37704626
Pubmed	Keratins of the human hair follicle.	KRT81 KRT83 KRT86	4.33e-07	4	167	3	15797458
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SEMA4F TICRR HCN1 GARS1 INTS1 CSMD2 ZNF831 SSPOP KMT2C AFAP1L2 DST ALDH16A1 LRRC7 CDK5R2 PLXNB3 DOP1B	5.94e-07	736	167	16	29676528
Pubmed	Interplay between scatter factor receptors and B plexins controls invasive growth.	PLXNB2 MST1R PLXNB3	1.08e-06	5	167	3	15184888
Pubmed	Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.	LEPR HOXA2 OTX1 FEZF1 SLIT3	1.57e-06	41	167	5	25810521
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	SEMA4F PLXNB2 OTX1 GLI3 SLIT3 NTN1 PLXNB3	2.71e-06	126	167	7	16284245
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	INTS1 KANSL3 ATP2C1 RPTOR KLHL13 LRRC7 ARHGAP21	9.76e-06	153	167	7	10718198
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	FNDC3A CEP68 KMT2C MRTFB DST ZBTB40 CLEC16A DOP1B	1.42e-05	225	167	8	12168954
Pubmed	KLF10 transcription factor regulates hepatic glucose metabolism in mice.	LEPR KLF10	2.29e-05	2	167	2	28836014
Pubmed	The Role of SLIT3-ROBO4 Signaling in Endoplasmic Reticulum Stress-Induced Delayed Corneal Epithelial and Nerve Regeneration.	ROBO4 SLIT3	2.29e-05	2	167	2	38700874
Pubmed	A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.	KRT83 KRT86	2.29e-05	2	167	2	15744029
Pubmed	MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity.	KMT2C TNS3	2.29e-05	2	167	2	33824309
Pubmed	Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response.	LEPR NTN1	2.29e-05	2	167	2	37037837
Pubmed	CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5.	CHD4 BAZ2A	2.29e-05	2	167	2	23796711
Pubmed	Congenital Erythropoietic Porphyria	GATA1 UROS	2.29e-05	2	167	2	24027798
Pubmed	A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.	KRT81 KRT86	2.29e-05	2	167	2	9665406
Pubmed	SLIT3-ROBO4 activation promotes vascular network formation in human engineered tissue and angiogenesis in vivo.	ROBO4 SLIT3	2.29e-05	2	167	2	24090675
Pubmed	A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.	KRT81 KRT86	2.29e-05	2	167	2	9402962
Pubmed	Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.	HMCN2 HMCN1	2.29e-05	2	167	2	32035013
Pubmed	Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation.	GRM5 LRRC7	2.29e-05	2	167	2	31582721
Pubmed	Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1.	SEMA4F OTX1	2.29e-05	2	167	2	11901358
Pubmed	Protein kinase D3 promotes gastric cancer development through p65/6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 activation of glycolysis.	PFKFB3 PRKD3	2.29e-05	2	167	2	31026442
Pubmed	FNDC3A is required for adhesion between spermatids and Sertoli cells.	FNDC3B FNDC3A	2.29e-05	2	167	2	16904100
Pubmed	Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes.	PKD1L2 PKD1L3	2.29e-05	2	167	2	12782129
Pubmed	Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.	KRT81 KRT83 KRT86	2.32e-05	12	167	3	10692104
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	INTS1 CHD4 PKD1L2 MTFR1L KMT2C USP5 OTX1 DST MARF1	2.78e-05	322	167	9	26514267
Pubmed	An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.	SEMA4F PLXNB2 PLXNB3	3.00e-05	13	167	3	24572910
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SOBP AFF3 FRYL SSPOP SBNO2 B4GALT1 KANSL3 BPTF KMT2C USF3 MRTFB ATP2C1 PTPRR RPTOR LOXL2 ANKRD11 NTN1 LRRC7 ZSWIM4 CLEC16A	3.36e-05	1489	167	20	28611215
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ATG2B C15orf39 GEMIN5 CHD4 MAP7D1 MRTFB DST GTF3C2 TACC3 ARHGAP21	3.74e-05	418	167	10	34709266
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	GATA1 CHD4 TUT1 POU6F1 RFPL1 THAP7 PIKFYVE KMT2C LDB3 OTX1 BAZ2A GLI3 TACC3	4.17e-05	709	167	13	22988430
Pubmed	Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.	SEMA4F PLXNB2 PLXNB3	4.74e-05	15	167	3	21122816
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLEKHG4 RGL3 GEMIN5 SIGLEC1 ZSWIM4	5.78e-05	85	167	5	15449545
Pubmed	Comprehensive analysis of keratin gene clusters in humans and rodents.	KRT81 KRT83 KRT86	5.82e-05	16	167	3	15085952
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	FNDC3A FHOD3 ZFYVE9 TRMT2A GTF3C2 CDC25C	5.94e-05	139	167	6	25476789
Pubmed	Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.	HMCN2 HMCN1	6.85e-05	3	167	2	12388743
Pubmed	Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1.	GATA1 PRKD3	6.85e-05	3	167	2	22983445
Pubmed	C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy.	TNS2 LEPR	6.85e-05	3	167	2	23401856
Pubmed	TARBP2 inhibits IRF7 activation by suppressing TRAF6-mediated K63-linked ubiquitination of IRF7.	IRF7 TARBP2	6.85e-05	3	167	2	30927622
Pubmed	Experimental validation of 5 in-silico predicted glioma biomarkers.	PLXNB2 SLIT3	6.85e-05	3	167	2	24158112
Pubmed	A secreted protein promotes cleavage furrow maturation during cytokinesis.	HMCN2 HMCN1	6.85e-05	3	167	2	21215633
Pubmed	LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.	AFF3 DST	6.85e-05	3	167	2	8662235
Pubmed	BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease.	BATF CSF2	6.85e-05	3	167	2	29376889
Pubmed	Sequence data and chromosomal localization of human type I and type II hair keratin genes.	KRT81 KRT86	6.85e-05	3	167	2	7556444
Pubmed	Leptin Signaling Suppression in Macrophages Improves Immunometabolic Outcomes in Obesity.	LEPR RPTOR	6.85e-05	3	167	2	35377454
Pubmed	Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis.	AMBP KMT2C	6.85e-05	3	167	2	24211404
Pubmed	Sequences and differential expression of three novel human type-II hair keratins.	KRT83 KRT86	6.85e-05	3	167	2	9084137
Pubmed	mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.	LEPR RPTOR	6.85e-05	3	167	2	21606597
Pubmed	Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin.	PLXNB2 PLXNB3	6.85e-05	3	167	2	16122393
Pubmed	Hemicentins assemble on diverse epithelia in the mouse.	HMCN2 HMCN1	6.85e-05	3	167	2	17015624
Pubmed	Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway.	B4GALT1 CSF2	6.85e-05	3	167	2	35926458
Pubmed	The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.	EPHB3 SLIT3 NTN1	8.41e-05	18	167	3	16854408
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FNDC3B PLEKHG4 GARS1 GEMIN5 CHD4 SRCAP CDCA2 EEF1B2 USP5 MAP7D1 DST GTF3C2 BAZ2A ERAL1 RPTOR EIF2B3 CORO7 TNS3	9.59e-05	1353	167	18	29467282
Pubmed	PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.	KRT81 KRT83 KRT86	9.96e-05	19	167	3	21285247
Pubmed	Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons.	HOXA2 SLIT3 NTN1	9.96e-05	19	167	3	23307742
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FAT3 CHD4 SRCAP PLEKHN1 BPTF LARP4B MAP7D1 ATP2C1 HMCN2 TRMT2A BAZ2A RPTOR GLI3 SIGLEC1 TAF4B TARBP2	1.02e-04	1116	167	16	31753913
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA4F PLXNB2 NTN1 PLXNB3	1.16e-04	52	167	4	26633812
Pubmed	Expression and roles of Slit/Robo in human ovarian cancer.	ROBO4 SLIT3	1.37e-04	4	167	2	21465248
Pubmed	Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.	LEPR HMCN1	1.37e-04	4	167	2	29488390
Pubmed	Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice.	MAGEL2 LEPR	1.37e-04	4	167	2	23341784
Pubmed	Targeting skeletal endothelium to ameliorate bone loss.	ROBO4 SLIT3	1.37e-04	4	167	2	29785024
Pubmed	Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells.	CCDC9B FHOD3	1.37e-04	4	167	2	19658189
Pubmed	Netrin 1 regulates ventral tangential migration of guidepost neurons in the lateral olfactory tract.	GLI3 NTN1	1.37e-04	4	167	2	16439477
Pubmed	Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses.	LEPR RPTOR	1.37e-04	4	167	2	37863051
Pubmed	DOCK5 regulates energy balance and hepatic insulin sensitivity by targeting mTORC1 signaling.	LEPR RPTOR	1.37e-04	4	167	2	31885214
Pubmed	Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.	TNS2 TNS3	1.37e-04	4	167	2	19194507
Pubmed	Aberrant methylation of ATG2B, ATG4D, ATG9A and ATG9B CpG island promoter is associated with decreased mRNA expression in sporadic breast carcinoma.	ATG9B ATG2B	1.37e-04	4	167	2	27265029
Pubmed	Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2.	HMCN2 HMCN1	1.37e-04	4	167	2	36007682
Pubmed	The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis.	FNDC3B FNDC3A	1.37e-04	4	167	2	32966780
Pubmed	A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus.	MST1R SIGLEC1	1.37e-04	4	167	2	30595553
Pubmed	Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site.	GATA1 CHD4	1.37e-04	4	167	2	18347053
Pubmed	Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.	PLXNB2 PLXNB3	1.37e-04	4	167	2	15147296
Pubmed	A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3.	GATA1 TACC3	1.37e-04	4	167	2	15234987
Pubmed	Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.	KRT81 KRT86	1.37e-04	4	167	2	9457912
Pubmed	Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways.	LEPR KLF10	1.37e-04	4	167	2	38582490
Pubmed	The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism.	SIK1 LEPR	1.37e-04	4	167	2	16148943
Pubmed	Endogenously activated mGlu5 metabotropic glutamate receptors sustain the increase in c-Myc expression induced by leukaemia inhibitory factor in cultured mouse embryonic stem cells.	GRM5 LIF	1.37e-04	4	167	2	16987252
Pubmed	Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.	ATG9B ATG2B	1.37e-04	4	167	2	19197948
Pubmed	Establishing a hematopoietic genetic network through locus-specific integration of chromatin regulators.	GATA1 CHD4	1.37e-04	4	167	2	23959865
Pubmed	IL-4 receptor dependent expansion of lung CD169+ macrophages in microfilaria-driven inflammation.	GATA1 SIGLEC1	1.37e-04	4	167	2	31469835
Pubmed	Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.	HMCN2 HMCN1	1.37e-04	4	167	2	34504132
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FNDC3B SPART CHD4 PRKD3 LARP4B MAP7D1 DST KLF10 ZBTB40 ARHGAP21	1.56e-04	497	167	10	23414517
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	LZTS3 PPRC1 SPART SSPOP CEP68	1.58e-04	105	167	5	9628581
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	AMBP PLXNB2 HMCN2 HMCN1 ADAMTSL5 NTN1	1.63e-04	167	167	6	22159717
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PPRC1 MAP7D1 BAZ2A KLHL13 LRRC7 CLEC16A ARHGAP21 PLXNB3 DOP1B	1.66e-04	407	167	9	12693553
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	BATF GAL3ST1 CHD4 ITGA2 SBNO2 KANSL3 MST1R KMT2C OTX1 DST GTF3C2 KLHL13 CHFR ATP13A3 DCAF11 ZNF333 DOP1B	1.74e-04	1293	167	17	15342556
Pubmed	Human transcription factor protein interaction networks.	SOBP GATA1 C15orf39 SRCAP KANSL3 CDCA2 BPTF KMT2C LARP4B MAP7D1 MIDN DST KLF10 GTF3C2 GLI3 MARF1 ZBTB40 RAI2	1.89e-04	1429	167	18	35140242
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	GARS1 CHD4 LIF DST LOXL2 ANKRD11 TACC3 TNS3	2.16e-04	332	167	8	37433992
Pubmed	The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.	TNS2 TNS3	2.27e-04	5	167	2	17190795
Pubmed	Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.	PLXNB2 PLXNB3	2.27e-04	5	167	2	12183458
Pubmed	Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases.	PFKFB3 CDC25C	2.27e-04	5	167	2	19473963
Pubmed	mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.	GTF3C2 RPTOR	2.27e-04	5	167	2	20543138
Pubmed	Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans.	ATG9B ATG2B	2.27e-04	5	167	2	22710871
Pubmed	mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).	LEPR RPTOR	2.27e-04	5	167	2	26042770
Pubmed	Vascular Robo4 restricts proangiogenic VEGF signaling in breast.	ROBO4 SLIT3	2.27e-04	5	167	2	20498081
Pubmed	Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.	EPHB3 GLI3 NTN1	2.61e-04	26	167	3	35927240
GeneFamily	Fibronectin type III domain containing	EPHB3 ROBO4 FNDC3B FNDC3A FNDC7 TNN EGFLAM	6.56e-05	160	113	7	555
GeneFamily	Keratins, type II	KRT81 KRT83 KRT86	6.23e-04	27	113	3	609
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TNS2 TNS3	1.06e-03	8	113	2	837
GeneFamily	Fibulins	HMCN2 HMCN1	1.06e-03	8	113	2	556
GeneFamily	Plexins	PLXNB2 PLXNB3	1.35e-03	9	113	2	683
GeneFamily	PHD finger proteins	CHD4 BPTF KMT2C BAZ2A	2.45e-03	90	113	4	88
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ROBO4 JAM2 HMCN2 HMCN1 SIGLEC1	3.41e-03	161	113	5	593
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	TICRR ATG2B FNDC3A FRYL BPTF KMT2C BAZ2A ZBTB40 ATP13A3	2.33e-06	180	166	9	M8239
Coexpression	NABA_ECM_GLYCOPROTEINS	NDNF SSPOP FNDC7 HMCN2 HMCN1 TNN SLIT3 NTN1 EGFLAM	3.80e-06	191	166	9	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	NDNF SSPOP FNDC7 HMCN2 HMCN1 TNN SLIT3 NTN1 EGFLAM	4.69e-06	196	166	9	M3008
Coexpression	GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP	VPS11 IRF7 TXNDC11 MIDN KLF10 SIGLEC1 CORO7 ARHGAP21 TNS3	4.88e-06	197	166	9	M3307
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	FNDC3A FRYL PIKFYVE BPTF USP6 LARP4B DST ZFYVE9 KLF10 MARF1 ATP13A3 CLEC16A DOP1B	9.20e-06	466	166	13	M13522
Coexpression	XIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_708_5P_GENES	PFKFB3 LDB3 FNDC7 ARMCX6 CLEC16A	1.46e-05	49	166	5	MM17508
Coexpression	XIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_669C_3P_GENES	SEMA4F PGBD1 FRYL PFKFB3 CSMD2 LDB3 USF3 BAZ2A	2.28e-05	183	166	8	MM17506
Coexpression	GSE8515_IL1_VS_IL6_4H_STIM_MAC_DN	KRT81 TUT1 SRCAP VSTM4 ADRA2B ZFYVE9 CORO7 CDK5R2	3.47e-05	194	166	8	M5767
Coexpression	GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP	INTS1 PLXNB2 BPTF TRMT2A ERAL1 GLI3 CHFR MADCAM1	4.30e-05	200	166	8	M7256
Coexpression	GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP	INTS1 SPART FNDC3A PRKD3 KANSL3 KLF10 CORO7 WASF1	4.30e-05	200	166	8	M5617
Coexpression	NABA_CORE_MATRISOME	NDNF SSPOP FNDC7 HMCN2 HMCN1 TNN SLIT3 NTN1 EGFLAM	5.92e-05	270	166	9	MM17057
Coexpression	NABA_CORE_MATRISOME	NDNF SSPOP FNDC7 HMCN2 HMCN1 TNN SLIT3 NTN1 EGFLAM	6.82e-05	275	166	9	M5884
Coexpression	NABA_MATRISOME	AMBP NDNF SEMA4F ADAMTS5 PLXNB2 SSPOP LIF FNDC7 HMCN2 CSF2 HMCN1 ADAMTSL5 LOXL2 TNN SLIT3 NTN1 EGFLAM PLXNB3	7.55e-05	1008	166	18	MM17056
Coexpression	NABA_MATRISOME	AMBP NDNF SEMA4F ADAMTS5 PLXNB2 SSPOP LIF FNDC7 HMCN2 CSF2 HMCN1 ADAMTSL5 LOXL2 TNN SLIT3 NTN1 EGFLAM PLXNB3	9.44e-05	1026	166	18	M5889
ToppCell	ILEUM-inflamed-(6)_ILC3\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KRT81 KRT86 AFF3 SPART PFKFB3 LIF DST CSF2 SNAP91 CRACDL DCAF11 TNS3	1.06e-11	195	166	12	c6968da7d2b60c2163e1ff0ffa41340e1ec1d2ed
ToppCell	mLN-ILC-ILC\|mLN / Region, Cell class and subclass	KRT81 KRT86 PFKFB3 PLEKHN1 LIF DST CSF2 KLF10 SNAP91 CRACDL TNS3	2.49e-10	199	166	11	ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCell	mLN-ILC\|mLN / Region, Cell class and subclass	KRT81 KRT86 PFKFB3 PLEKHN1 LIF DST CSF2 KLF10 SNAP91 CRACDL TNS3	2.49e-10	199	166	11	d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCell	mLN-(3)_ILC\|mLN / shred on region, Cell_type, and subtype	KRT81 KRT86 PFKFB3 PLEKHN1 LIF DST CSF2 KLF10 SNAP91 CRACDL TNS3	2.49e-10	199	166	11	00e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCell	mLN-(3)_ILC-(30)_ILC\|mLN / shred on region, Cell_type, and subtype	KRT81 KRT86 PFKFB3 PLEKHN1 LIF DST CSF2 KLF10 SNAP91 CRACDL TNS3	2.49e-10	199	166	11	33ac6d77099076df01299be429f4ba96f2f34cc1
ToppCell	Sigmoid-ILC\|Sigmoid / Region, Cell class and subclass	KRT81 KRT83 KRT86 AFF3 FHOD3 PFKFB3 LIF CSF2 SNAP91 CRACDL FOXI2	2.63e-10	200	166	11	dfb06821f1019833f5d81f9c93808219b5fef407
ToppCell	Sigmoid-(3)_ILC\|Sigmoid / shred on region, Cell_type, and subtype	KRT81 KRT83 KRT86 AFF3 FHOD3 PFKFB3 LIF CSF2 SNAP91 CRACDL FOXI2	2.63e-10	200	166	11	a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCell	Sigmoid-(3)_ILC-(30)_ILC\|Sigmoid / shred on region, Cell_type, and subtype	KRT81 KRT83 KRT86 AFF3 FHOD3 PFKFB3 LIF CSF2 SNAP91 CRACDL FOXI2	2.63e-10	200	166	11	c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCell	Sigmoid-ILC-ILC\|Sigmoid / Region, Cell class and subclass	KRT81 KRT83 KRT86 AFF3 FHOD3 PFKFB3 LIF CSF2 SNAP91 CRACDL FOXI2	2.63e-10	200	166	11	4ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|343B / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG4 KRT81 KRT86 SRCAP PRKD3 SLFN12L ADRA2B AFAP1L2 TRMT2A TEDC1	4.18e-10	157	166	10	0362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT81 KRT83 KRT86 AFF3 PFKFB3 LIF CSF2 SNAP91 CRACDL DCAF11	8.58e-10	169	166	10	d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCell	(3)_ILC\|World / shred on Cell_type and subtype	KRT81 KRT86 AFF3 PFKFB3 LIF DST CSF2 SNAP91 CRACDL TNS3	4.38e-09	200	166	10	03554b3f323785b1e0b48fa32de0d92065dd798e
ToppCell	(30)_ILC\|World / shred on Cell_type and subtype	KRT81 KRT86 AFF3 PFKFB3 LIF DST CSF2 SNAP91 CRACDL TNS3	5.29e-09	204	166	10	bd9fbd278c05e396463704d711b60d47699e3c09
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT81 KRT83 KRT86 AFF3 PLEKHN1 LIF CSF2 SNAP91 CRACDL	1.12e-08	163	166	9	00e791358a7eb6c3e95f87afe22153845012e4a1
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	KRT81 FAT3 KRT86 PLEKHN1 LIF DST CSF2 SNAP91 CRACDL	3.86e-08	188	166	9	de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	KRT81 FAT3 KRT86 PLEKHN1 LIF DST CSF2 SNAP91 CRACDL	3.86e-08	188	166	9	f4734d5b703678670ece204a0519cf015e180a6e
ToppCell	ILEUM-non-inflamed-(6)_ILC3\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KRT81 KRT86 AFF3 SPART LIF CSF2 CRACDL DCAF11 TNS3	4.42e-08	191	166	9	6eaf72b41084404bee0db04e4605db745a74995f
ToppCell	ILEUM-inflamed-(6)_ILC-(6)_ILC3\|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KRT81 KRT86 AFF3 SPART PFKFB3 LIF DST DCAF11 TNS3	6.28e-08	199	166	9	02879df850b0c72b57d7b22cfc43f3407e182dcb
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT81 KRT86 AFF3 PFKFB3 LIF CSF2 SNAP91 DCAF11	2.67e-07	171	166	8	6ab7f103cbdbd49ef687cbb8a42ddc5517af0f7f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG4 PI16 ATG2B SRCAP ADRA2B AFAP1L2 TRMT2A TEDC1	3.05e-07	174	166	8	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG4 PI16 ATG2B SRCAP ADRA2B AFAP1L2 TRMT2A TEDC1	3.19e-07	175	166	8	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PI16 BATF KRT81 KRT83 KRT86 LIF SLFN12L SNAP91	3.95e-07	180	166	8	a999a6d219a8e58a8b63802ddf8c95ffaab9cfa0
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LZTS3 AFF3 ADAMTS5 VSTM4 DST SNAP91 LOXL2 RAI2	5.07e-07	186	166	8	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRYL JAM2 MRTFB AFAP1L2 DST PTPRR NTN1 ATP13A3	5.28e-07	187	166	8	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	KRT81 KRT86 LIF DST CSF2 SNAP91 CRACDL FOXI2	6.44e-07	192	166	8	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT81 KRT83 KRT86 AFF3 PFKFB3 LIF CRACDL DCAF11	7.24e-07	195	166	8	69201b1172bcf0999c726516e4d30863afceab0b
ToppCell	ILEUM-non-inflamed-(6)_ILC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KRT81 KRT86 AFF3 LIF CSF2 CRACDL DCAF11 TNS3	7.82e-07	197	166	8	76a233eb9611d24b9bb9f4359c26606332a3c29e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LZTS3 GAL3ST1 CSMD2 GRM5 TMEM132C AFAP1L2 LRRC7 PLXNB3	8.44e-07	199	166	8	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LZTS3 GAL3ST1 CSMD2 GRM5 TMEM132C AFAP1L2 LRRC7 PLXNB3	8.44e-07	199	166	8	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	Smart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EPHB3 KRT86 PLEKHN1 DST ZFYVE9 FOXI2 WASF1	1.42e-06	148	166	7	f90ee6fbd71b5e0512af34867202f38409f4de38
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GAL3ST1 TNS2 CSMD2 GRM5 TMEM132C AFAP1L2 LRRC7	1.93e-06	155	166	7	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	ATG9B KRT81 AFF3 DST CRACDL KLHL13 UBXN10	2.69e-06	163	166	7	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INTS1 JAM2 OTX1 RPTOR ABCB8 DCAF11 TAF4B	3.16e-06	167	166	7	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-ILC3\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BATF KRT81 KRT86 PLEKHN1 LIF CSF2 CRACDL	3.29e-06	168	166	7	4f2f78e14f044b535847bcdbbcec8c0fc8529870
ToppCell	facs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B C15orf39 SSPOP TXNDC11 FNDC7 LOXL2 MADCAM1	3.42e-06	169	166	7	b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	KRT86 AFF3 LIF ZFYVE9 CSF2 CRACDL TNS3	3.56e-06	170	166	7	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDCA2 LDB3 LOXL2 SLIT3 TACC3 CDC25C TEDC1	4.47e-06	176	166	7	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	KRT81 KRT86 LIF SLFN12L ZFYVE9 SNAP91 DCAF11	5.18e-06	180	166	7	27672ac6a02172a31851f18decb9acffa8f5a703
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAM2 MRTFB AFAP1L2 PTPRR KLHL13 NTN1 ATP13A3	5.57e-06	182	166	7	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAM2 MRTFB AFAP1L2 PTPRR KLHL13 NTN1 ATP13A3	5.57e-06	182	166	7	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	wk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	BATF KRT81 KRT83 KRT86 LIF SNAP91 DCAF11	5.57e-06	182	166	7	6bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT81 KRT83 KRT86 AFF3 LIF CRACDL DCAF11	5.78e-06	183	166	7	d4a558bc0b8e11be195a7da1468ab38eb477117d
ToppCell	PCW_13-14-Neuronal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GAL3ST1 FHOD3 CSMD2 PTPRR KLHL13 EGFLAM CDK5R2	5.99e-06	184	166	7	65cf3460125e3dbc34978957bc138a449f71f7df
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	KRT81 KRT86 AFF3 LIF DST CSF2 SNAP91	5.99e-06	184	166	7	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 FAT3 LEPR TMEM132C LOXL2 KLHL13 NTN1	6.20e-06	185	166	7	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 FAT3 LEPR TMEM132C LOXL2 KLHL13 NTN1	6.20e-06	185	166	7	049d793d043d5d434f143025de49dd210d18756c
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 FAT3 LEPR TMEM132C LOXL2 KLHL13 NTN1	6.20e-06	185	166	7	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 JAM2 MRTFB AFAP1L2 PTPRR NTN1 ATP13A3	6.42e-06	186	166	7	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNS2 JAM2 MRTFB AFAP1L2 DST PTPRR ATP13A3	6.42e-06	186	166	7	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL3 ITGA2 DST HMCN1 CRACDL KLHL13 NTN1	6.65e-06	187	166	7	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	P15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SHISA5 JAM2 MRTFB DST PTPRR ARMCX6 ATP13A3	6.89e-06	188	166	7	50b27fc12347ca16bd62333baf345c83cb422a8f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT3 TMEM132C VSTM4 DST HMCN1 GLI3 SLIT3	7.13e-06	189	166	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 ADAMTS5 TMEM132C VSTM4 KLHL13 SLIT3 NTN1	7.13e-06	189	166	7	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	PI16 ADAMTS5 GRM5 GLI3 SLIT3 FRMPD3 WASF1	7.38e-06	190	166	7	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 FHOD3 ADAMTS5 TMEM132C VSTM4 SLIT3 NTN1	7.64e-06	191	166	7	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	C2CD4B LEPR JAM2 MRTFB AFAP1L2 PNPLA1 PTPRR	7.64e-06	191	166	7	27a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	C2CD4B LEPR JAM2 MRTFB AFAP1L2 PNPLA1 PTPRR	7.64e-06	191	166	7	1dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B C15orf39 SIK1 FNDC3A FHOD3 TXNDC11 TNS3	7.90e-06	192	166	7	6417468829517a0f6e04e7e44eec1622001d4c5c
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	KRT81 KRT86 AFF3 TMEM132C DST CRACDL WASF1	8.18e-06	193	166	7	826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT3 AFF3 TMEM132C SLFN12L DST GLI3 SLIT3	8.46e-06	194	166	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	ILEUM-inflamed-(6)_ILC\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KRT81 KRT86 AFF3 PFKFB3 LIF CSF2 SNAP91	8.46e-06	194	166	7	4d51d49366c34ff1241770b4acc0167a43b3155a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGEL2 SOBP FHOD3 ITGA2 PTPRR KLHL13 NTN1	8.74e-06	195	166	7	6c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FAT3 AFF3 TMEM132C SLFN12L DST GLI3 SLIT3	8.74e-06	195	166	7	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 AFF3 GRM5 MRTFB SNAP91 PTPRR LRRC7	9.04e-06	196	166	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ROBO4 C2CD4B LEPR JAM2 MRTFB AFAP1L2 LOXL2	9.04e-06	196	166	7	5609b2d93172a488b35d854298a3a4e504e17e28
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NDNF FAT3 AFF3 TMEM132C DST GLI3 SLIT3	9.35e-06	197	166	7	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ROBO4 C2CD4B LEPR JAM2 MRTFB AFAP1L2 LOXL2	9.66e-06	198	166	7	68ee0baa2f5cf239f2356cc59fee9041a7732bba
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 AFF3 GRM5 MRTFB SNAP91 PTPRR LRRC7	9.66e-06	198	166	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HCN1 AFF3 GRM5 MRTFB SNAP91 PTPRR LRRC7	9.66e-06	198	166	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT3 TMEM132C VSTM4 DST HMCN1 GLI3 SLIT3	9.66e-06	198	166	7	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	ILEUM-non-inflamed-(6)_ILC-(6)_ILC3\|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KRT81 KRT86 AFF3 SPART DST DCAF11 TNS3	9.98e-06	199	166	7	ba144739f65560207303c0143e8de1e86922bebb
ToppCell	control-HLA-DR+_CD83+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FNDC3B C15orf39 ARHGEF10L MIDN DST KLF10 SIGLEC1	9.98e-06	199	166	7	f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LEPR JAM2 AFAP1L2 PNPLA1 HMCN1 PTPRR ATP13A3	9.98e-06	199	166	7	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ROBO4 LEPR BPTF KMT2C MRTFB DST HMCN1	1.03e-05	200	166	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	HCN1 AFF3 GRM5 MRTFB SNAP91 PTPRR LRRC7	1.03e-05	200	166	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ROBO4 STIM2 ITGA2 LEPR BPTF MRTFB DST	1.03e-05	200	166	7	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PI16 SRARP JAM2 CEP68 DST HMCN1 ATP13A3	1.03e-05	200	166	7	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LZTS3 GAL3ST1 GRM5 TMEM132C AFAP1L2 LRRC7 PLXNB3	1.03e-05	200	166	7	ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ROBO4 STIM2 LEPR JAM2 BPTF MRTFB DST	1.03e-05	200	166	7	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TICRR FAT3 FHOD3 ADAMTS5 LDB3 HMCN2	2.56e-05	155	166	6	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	Severe-Lymphoid-NK-Proliferating_T\|Severe / Condition, Lineage, Cell class and cell subclass	NDNF SEMA4F KRT81 KRT86 ZNF831 CSF2	3.06e-05	160	166	6	cb2276d9bd78508644420e9580d3c17b914224cb
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	PI16 SOBP AFF3 JAM2 TMEM132C HMCN2	3.06e-05	160	166	6	8a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCell	TCGA-Bladder-Solid_Tissue_Normal\|TCGA-Bladder / Sample_Type by Project: Shred V9	PI16 SOBP AFF3 JAM2 TMEM132C HMCN2	3.06e-05	160	166	6	d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	PI16 SOBP AFF3 JAM2 TMEM132C HMCN2	3.06e-05	160	166	6	c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-ILC3\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT81 KRT86 PLEKHN1 LIF CSF2 CRACDL	3.16e-05	161	166	6	584e44e6048c2678eb72cd23a86f48f2466c5da4
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDNF AFF3 GATA1 MFSD2B ITGA2 ZNF831	3.39e-05	163	166	6	924c666596bbb42d7876c9b164a725277f3efa5f
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCHCR1 PPRC1 ITGA2 JAM2 PTPRR ZSWIM4	3.63e-05	165	166	6	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KRT81 KRT86 AFF3 PLEKHN1 LIF CSF2	3.88e-05	167	166	6	94642b3dae035fedb6e8b9745f440096a4539f3c
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KRT81 KRT86 AFF3 PLEKHN1 LIF CSF2	3.88e-05	167	166	6	42b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KRT81 KRT86 AFF3 PLEKHN1 LIF CSF2	3.88e-05	167	166	6	ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NDNF KRT81 KRT86 PGBD1 PLEKHN1 TNS3	4.01e-05	168	166	6	6501495b7ad252af330b18011696c43031541018
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	AMBP KRT86 AFF3 LIF CSF2 CRACDL	4.01e-05	168	166	6	d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT81 KRT86 AFF3 PLEKHN1 LIF CSF2	4.15e-05	169	166	6	e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCell	droplet-Lung-nan-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F TICRR PKD1L3 CDCA2 TACC3 CDC25C	4.15e-05	169	166	6	df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F TICRR PKD1L3 CDCA2 TACC3 CDC25C	4.15e-05	169	166	6	f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT81 KRT86 AFF3 PLEKHN1 LIF CSF2	4.15e-05	169	166	6	d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCell	BAL-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT81 KRT86 AFF3 PLEKHN1 LIF CSF2	4.15e-05	169	166	6	58f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 JAM2 HMCN1 PTPRR SLIT3 ARMCX6	4.29e-05	170	166	6	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 JAM2 HMCN1 PTPRR SLIT3 ARMCX6	4.29e-05	170	166	6	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 JAM2 HMCN1 PTPRR SLIT3 ARMCX6	4.29e-05	170	166	6	3232db50b1a40f861e981a1b9c9073b81af9f832
Computational	Neighborhood of DLG1	ATG2B TNS2 FRYL MRTFB MARF1 ARHGAP21	8.95e-05	79	100	6	GCM_DLG1
Disease	MONILETHRIX	KRT81 KRT83 KRT86	1.59e-07	3	161	3	158000
Disease	Beaded hair	KRT81 KRT83 KRT86	1.59e-07	3	161	3	cv:C0546966
Disease	monilethrix (is_implicated_in)	KRT81 KRT83 KRT86	1.59e-07	3	161	3	DOID:0050472 (is_implicated_in)
Disease	Monilethrix	KRT81 KRT83 KRT86	6.35e-07	4	161	3	C0546966
Disease	Deficiency of Uroporphyrinogen III Synthase	GATA1 UROS	2.96e-05	2	161	2	C2718078
Disease	Porphyria, Erythropoietic	GATA1 UROS	2.96e-05	2	161	2	C0162530
Disease	hair disease (is_implicated_in)	KRT81 KRT86	2.96e-05	2	161	2	DOID:421 (is_implicated_in)
Disease	pulse pressure measurement	FNDC3B RGL3 FAT3 PGBD1 FHOD3 FRYL SRCAP PKD1L3 ZNF831 PLXNB2 SSPOP PRKD3 CEP68 ADRA2B RPTOR SLIT3 ANKRD11 CORO7 CLEC16A TNS3	7.54e-05	1392	161	20	EFO_0005763
Disease	IGF-1 measurement	FNDC3B TICRR C2CD4B SRCAP GRM5 LEPR VSTM4 ALDH16A1 SLIT3 CDC25C DOP1B	8.14e-05	488	161	11	EFO_0004627
Disease	preeclampsia, hypertension, pregnancy-induced	RGL3 TNS2 ZNF831	8.47e-05	16	161	3	EFO_0000668, MONDO_0024664
Disease	Crohn's disease (implicated_via_orthology)	PIKFYVE MADCAM1	8.84e-05	3	161	2	DOID:8778 (implicated_via_orthology)
Disease	reticulocyte measurement	FNDC3B AFF3 MFSD2B PLXNB2 SBNO2 PIKFYVE VSTM4 SLFN12L EEF1B2 LARP4B ERAL1 ZBTB40 SIGLEC1 CORO7 ARHGAP21 TNS3	2.21e-04	1053	161	16	EFO_0010700
Disease	hypertension, pregnancy-induced	RGL3 ZNF831	2.93e-04	5	161	2	MONDO_0024664
Disease	pathological myopia	SEMA4F SOBP CHD4 RPTOR MIPEP	3.66e-04	111	161	5	EFO_0004207
Disease	multiple myeloma	CCHCR1 TICRR FNDC3A SRCAP ANKRD11	3.81e-04	112	161	5	EFO_0001378
Disease	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1	HCN1 SIK1	4.37e-04	6	161	2	C3463992
Disease	aggressive behaviour measurement, ADHD symptom measurement	HCN1 GRM5 MST1R RPTOR	5.30e-04	68	161	4	EFO_0007826, EFO_0007860
Disease	retinal detachment	FAT3 GRM5	6.10e-04	7	161	2	EFO_0005773
Disease	X-linked infantile spasms	HCN1 SIK1	8.11e-04	8	161	2	C4552072
Disease	lifestyle measurement, systolic blood pressure	CDCA2 CHFR	1.04e-03	9	161	2	EFO_0006335, EFO_0010724
Disease	obesity (implicated_via_orthology)	STIM2 PLXNB2 LEPR PNPLA1 CORO7 PLXNB3	1.20e-03	215	161	6	DOID:9970 (implicated_via_orthology)
Disease	IgG fucosylation measurement	B4GALT1 TEDC1	1.29e-03	10	161	2	EFO_0008427
Disease	Carcinoma, Transitional Cell	AMBP KMT2C TACC3	1.46e-03	41	161	3	C0007138
Disease	hypertension	TICRR RGL3 ZNF831 GRM5 PLXNB2 RPTOR LRRC7	1.54e-03	307	161	7	EFO_0000537
Disease	neutrophil percentage of granulocytes	BATF KANSL3 BPTF LARP4B CSF2 CLEC16A	1.62e-03	228	161	6	EFO_0007994
Disease	hypertrophic cardiomyopathy	FNDC3B SRARP FHOD3 KMT2C	1.64e-03	92	161	4	EFO_0000538
Disease	Squamous cell carcinoma of esophagus	CCHCR1 FAT3 KMT2C LOXL2	1.85e-03	95	161	4	C0279626
Disease	IgG galactosylation measurement	B4GALT1 TEDC1	1.88e-03	12	161	2	EFO_0008425
Disease	basophil count, eosinophil count	BATF KANSL3 BPTF LARP4B CSF2 CLEC16A	2.15e-03	241	161	6	EFO_0004842, EFO_0005090
Disease	developmental disorder of mental health (implicated_via_orthology)	SRCAP PLXNB2 PLXNB3	2.44e-03	49	161	3	DOID:0060037 (implicated_via_orthology)
Disease	Diabetic Neuralgia	GRM5 LEPR	2.58e-03	14	161	2	C0751074
Disease	Diabetic Neuropathies	GRM5 LEPR	2.58e-03	14	161	2	C0011882
Disease	silicosis (biomarker_via_orthology)	CHIA CSF2	2.58e-03	14	161	2	DOID:10325 (biomarker_via_orthology)
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	GRM5 LEPR	2.58e-03	14	161	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	GRM5 LEPR	2.58e-03	14	161	2	C0271673
Disease	Diabetic Mononeuropathy	GRM5 LEPR	2.58e-03	14	161	2	C0271678
Disease	Diabetic Autonomic Neuropathy	GRM5 LEPR	2.58e-03	14	161	2	C0271686
Disease	Diabetic Amyotrophy	GRM5 LEPR	2.58e-03	14	161	2	C0271685
Disease	Diabetic Polyneuropathies	GRM5 LEPR	2.58e-03	14	161	2	C0271680
Disease	Diabetic Asymmetric Polyneuropathy	GRM5 LEPR	2.58e-03	14	161	2	C0393835
Disease	quinate measurement	ITGA2 LEPR	2.97e-03	15	161	2	EFO_0021167
Disease	red blood cell density measurement	AFF3 MFSD2B CHD4 MTFR1L B4GALT1 PRKD3 LARP4B DST PNPLA1 ZBTB40 TAF4B TNS3	3.33e-03	880	161	12	EFO_0007978
Disease	preeclampsia, parental genotype effect measurement	CCHCR1 ZNF831	3.38e-03	16	161	2	EFO_0000668, EFO_0005939
Disease	alcohol dependence measurement	BPTF ARHGAP21 TNS3	3.40e-03	55	161	3	EFO_0007835
Disease	Astrocytosis	ITGA2 LEPR	3.81e-03	17	161	2	C3887640
Disease	Gliosis	ITGA2 LEPR	3.81e-03	17	161	2	C0017639
Disease	mean reticulocyte volume	PPRC1 AFF3 C19orf47 C15orf39 CHD4 TXNDC11 SBNO2 KLF10 ZBTB40 TACC3 ARHGAP21	4.55e-03	799	161	11	EFO_0010701
Disease	reticulocyte count	CCHCR1 FNDC3B MFSD2B GEMIN5 PLXNB2 SBNO2 PIKFYVE VSTM4 SLFN12L EEF1B2 ERAL1 ZBTB40 TNS3	4.92e-03	1045	161	13	EFO_0007986

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPCVTTEVPSILAAH	PI16	281	Q6UXB8
LSACLAVSAGPVPTP	AMBP	11	P02760
PAELTPSPCTQVKSA	C2orf16	646	Q68DN1
VAVSAAAPPPAVPCA	AFF3	556	P51826
SVPVPHTTALSLPAC	B4GALT1	116	P15291
PTVADPSATVHPTIC	ARHGEF10L	881	Q9HCE6
VTTLSQDSCLPPAAP	EGFLAM	131	Q63HQ2
AAPTLATPTLATPAC	CCDC187	871	A0A096LP49
PLDVAPEPACVAAVA	ANKRD11	2076	Q6UB99
PQCVPVTCPDVSSIS	CSMD2	2586	Q7Z408
TNVSPNCPPAEATAL	CEP68	351	Q76N32
AATESVPCSPSPLAG	C19orf47	116	Q8N9M1
AVGCTVVALVPPASP	ALDH16A1	191	Q8IZ83
TQCSHPSAIDPEAIP	ATP13A3	796	Q9H7F0
EALPPRASCETPAST	ADAMTS5	201	Q9UNA0
VSPAASPEISPEVCP	BAZ2A	441	Q9UIF9
SPEISPEVCPAASTV	BAZ2A	446	Q9UIF9
PEVCPAASTVVSPAV	BAZ2A	451	Q9UIF9
RISFPPSCPDAVVAT	AFAP1L2	621	Q8N4X5
KAVTPASAPDCTPVN	AFAP1L2	771	Q8N4X5
SASCTAPAQPIEPIT	CHIA	391	Q9BZP6
EPQAVPVSPASACSP	ADRA2B	311	P18089
PATPTPVAAALDACS	SNAP91	461	O60641
LAQATAVAAPCPPVT	BPTF	2786	Q12830
LAVPVPTVPAAAATC	CDK5R2	121	Q13319
TSPTPDPTVREALCA	ARMCX6	166	Q7L4S7
ETTPCSKVTAPQPAA	ATP2C1	191	P98194
PVCSTAPVETEPKLS	ATG2B	241	Q96BY7
CIKIPVAPPTTAASS	NTN1	451	O95631
SPLVLPQEAPCSSST	RAI2	136	Q9Y5P3
GLPVSCTAESPTPQA	UROS	236	P10746
HSSPCPPSITENVTL	GLI3	1061	P10071
NSPVSESALCIPSSP	GRM5	1181	P41594
APVENCTPLSSVSRP	KMT2C	1921	Q8NEZ4
SPAALVPGDPEVACT	MADCAM1	121	Q13477
ACSPPSPSALIQELE	LZTS3	311	O60299
SAPLSAPQAVHCPSI	MAGEL2	571	Q9UJ55
PIEHAPVCTSQATTP	LDB3	301	O75112
PVCTSQATTPLLPAS	LDB3	306	O75112
ASPFPACKPVVVVSS	INTS1	1571	Q8N201
CTPLPVAAQSTTLPS	LRRC7	541	Q96NW7
SIDPKVNSSPSVCVP	DST	2116	Q03001
APCCPSDINPVLVSS	FNDC7	371	Q5VTL7
AASLPCVASGVPAPT	HMCN2	991	Q8NDA2
APVVLTCHSTGIPAP	HMCN2	3866	Q8NDA2
AGSPLPITPVNATCA	LIF	21	P15018
RNSVSPPPTVSELCA	DOP1B	466	Q9Y3R5
CGPSPPCITTVSVNE	KRT86	71	O43790
LPVVVSREPSVPASC	LARP4B	576	Q92615
PAVVSCVPGQVFSPD	LOXL2	296	Q9Y4K0
APCTLESPIRAAAVP	C2CD4B	41	A6NLJ0
EPPSAACLDLQASPS	FOXI2	221	Q6ZQN5
ACLDLQASPSPSAPE	FOXI2	226	Q6ZQN5
VASTASSVPCSPQEP	CCDC9B	401	Q6ZUT6
TSCLVPPAEPLPDTA	CORO7	396	P57737
VLSDVIPSIPSSPCL	FAM199X	151	Q6PEV8
EALCNTTSECPPPVI	PLXNB2	791	O15031
VAVTGPVIDSPDCVP	PLXNB3	86	Q9ULL4
PHCATLSVIPTPEAN	CSNKA2IP	496	A0A1B0GTH6
TSAALPSCLPPEVPT	PFKFB3	486	Q16875
EECASAPAPVPQSST	DCAF11	526	Q8TEB1
FSQPDSSVTPCVPAV	ERAL1	76	O75616
VRCSPPETLASTPDS	FRYL	886	O94915
ASLPDCSSSRQPIPV	MRTFB	631	Q9ULH7
AAKPSASAPIPITCS	POU6F1	106	Q14863
ASAPIPITCSETPTV	POU6F1	111	Q14863
EFTCESPVSAPVSPL	PNPLA1	336	Q8N8W4
PTAIPAVLPAASPCS	PRKD3	16	O94806
DNTPLSVTVTPCDAP	NDNF	71	Q8TB73
PTSLVIAPGTCIPNA	EPHB3	231	P54753
SLDSPPTCVLPDSVV	LEPR	521	P48357
RCEATATPGPVTVSP	MFSD2B	211	A6NFX1
EVPELPSVPLLCSAS	MTFR1L	196	Q9H019
LVAPAVPSCEVPSSA	JAM2	131	P57087
LSPSPSACTAVQEPS	IRF7	271	Q92985
VIEPPAASCPSSPRI	RGL3	501	Q3MIN7
SFSPATQPCPSLIDV	ITGA2	161	P17301
AVTPAQTPTLAPDPC	ADAMTSL5	346	Q6ZMM2
VVCAPEDVASPFPTA	CRACDL	391	Q6NV74
DTSFTVCPDVPRTPV	CDC25C	36	P30307
VSVPEPLAAPSNTSC	OTX1	191	P32242
VPASCLPPPDSAVTL	PKD1L2	621	Q7Z442
SVSLECESNAVPPPV	HMCN1	3076	Q96RW7
SNPVTLTCDATGIPP	HMCN1	3166	Q96RW7
PEIKATTATSVCPSP	PTPRR	311	Q15256
ATAPCLPSPTATRQA	KCTD18	386	Q6PI47
CSVSVLDPSEPRTPV	PIKFYVE	241	Q9Y2I7
ASTVCPTREDSPPQA	GATA1	106	P15976
LASTTPEAAASCSPP	GAL3ST1	41	Q99999
SALCPEEPPVHSSAQ	EIF2B3	331	Q9NR50
PASELPVAVTSRPDC	CHFR	621	Q96EP1
PPTPETSCATQIITF	CSF2	106	P04141
TAVCSPPVQSPLAAR	HCN1	701	O60741
ACTLTVFPPEETTPS	KLHL13	631	Q9P2N7
SSRCTPPPADSELVS	FRMPD3	546	Q5JV73
SEVVACVTPPSVPGI	FNDC3A	841	Q9Y2H6
LVLCQTPASAPDPVS	FNDC3B	851	Q53EP0
TPASAPDPVSTLCVL	FNDC3B	856	Q53EP0
PLCSVLAASTPSPPE	BATF	91	Q16520
VVCSVAPNLPAVSPC	FAT3	4281	Q8TDW7
SLDLTSPAAPACLAP	FHOD3	511	Q2V2M9
VSSPRPPECSASAPV	CCHCR1	716	Q8TD31
PPECSASAPVAAAVP	CCHCR1	721	Q8TD31
DLSPTAPCPAAATAS	ATG9B	781	Q674R7
DSSSSCISAAVPVPP	MARF1	1686	Q9Y4F3
AAVPVCPRSASASPL	MAP7D1	356	Q3KQU3
SDAVPDVRSPATPAC	CDCA2	301	Q69YH5
TSSCLFVPISSEPPE	KANSL3	601	Q9P2N6
SETVICRSQPAPVSP	KLF10	236	Q13118
CPGNTTAIPAVPTIT	KRTAP29-1	6	A8MX34
TEITSPTPAPRAQVC	H1-9P	36	P60008
AVFEAVSSPPPADLC	EEF1B2	36	P24534
TAPETAIECTQAPAP	CHD4	1586	Q14839
EQADPSAPCLAPSSL	PPRC1	1361	Q5VV67
CGPSPPCITTVSVNE	KRT83	76	P78385
PSLAECLTSFPPVAD	HOXA2	16	O43364
ALCEAEEAPPASSTP	ABCB8	111	Q9NUT2
DPSIASPVSSPCRPV	MIDN	181	Q504T8
SVCVEPTASQPLRSP	TAF4B	51	Q92750
LSICPVINPGTTDAP	RFPL1	296	O75677
SSALSCPTVSVPPAA	TRMT2A	21	Q8IZ69
CPTVSVPPAAPAALE	TRMT2A	26	Q8IZ69
ISLPTAPPAAGTECL	PRSS3P2	126	Q8NHM4
VCAPAAVATSPPGAI	TACC3	241	Q9Y6A5
PSVPVSVPASDPRSC	PLEKHN1	496	Q494U1
SVASASFPVSPLCPQ	SRARP	116	Q8NEQ6
PVATAAHVVLPCSPS	SEMA4F	576	O95754
CARSPSAVPSTVAPL	SSPOP	3211	A2VEC9
TIPPDDSCPTVNSIV	TMEM132C	1061	Q8N3T6
ASLCVSQVPAAPAHP	PLEKHG4	656	Q58EX7
PAAVPSAPAFSCSDL	FEZF1	106	A0PJY2
LSAASCPPISLPAAA	GARS1	36	P41250
PPIQASCLSDASVEP	PKD1L3	981	Q7Z443
APCIVVSPSTTASPA	SIK1B	486	A0A0B4J2F2
APCIVVSPSTTASPA	SIK1	486	P57059
RCAVPEASVPASVEP	SHISA5	71	Q8N114
APVATASSLPPKTCD	SBNO2	76	Q9Y2G9
ECAPQIPCSTPIATE	PGBD1	291	Q96JS3
VAPACSPVLVPASAL	SRCAP	1541	Q6ZRS2
DSPVLSCFPPSELQA	TNS3	981	Q68CZ2
PDLPADLFTSCLTTP	RPTOR	256	Q8N122
ADCVFIDASSPPSPR	ROBO4	926	Q8WZ75
TCFPVEEASAPATLP	THAP7	146	Q9BT49
PLSTPAAACTEPVGE	CLEC16A	1026	Q2KHT3
VTCFSLALPSPPAVA	C15orf39	701	Q6ZRI6
ALASVLSGPPAVACP	SLIT3	21	O75094
ICSEPVAASPAPAGE	ZNF511	206	Q8NB15
PASLSLPSQSCPAEA	SPART	156	Q8N0X7
EVFVSGSTPPPSCAV	TICRR	1821	Q7Z2Z1
IFPAIPGTEPTVVSC	VPS11	131	Q9H270
LVDRACSTPPGPQTV	MIPEP	91	Q99797
CEELPSPASTSSPVS	SLFN12L	366	Q6IEE8
VASAPATLEPPGCSN	TNN	21	Q9UQP3
SPDPDILSVSSCPAL	STIM2	556	Q9P246
DTANCSVTKIPTPVP	SOBP	336	A7XYQ1
SPVSGPPAVCETLAV	SOGA3	291	Q5TF21
PPAVCETLAVASASP	SOGA3	296	Q5TF21
ASPLDPQALACTPAS	TUT1	246	Q9H6E5
SLVCPAVPTSAKSPV	SPATA31D1	1536	Q6ZQQ2
GTCAPEVPAAASQPT	TEDC1	331	Q86SX3
APAVSREPVICTPVS	GEMIN5	796	Q8TEQ6
KPCASANVLIPSPSD	USF3	936	Q68DE3
VPEGAPITVTCADPA	SIGLEC1	1271	Q9BZZ2
PITVTCADPAAHAPT	SIGLEC1	1276	Q9BZZ2
SPLALEAPAPAAVCA	TMEM275	146	A0A0U1RQS6
APGLPTACSQEPVTF	ZNF333	191	Q96JL9
DPPTITASPCCNTVV	TXNDC11	441	Q6PKC3
SCSPQPTDSLVLAPA	UTS2R	361	Q9UKP6
ELSTALPAPVSCPEG	GTF3C2	201	Q8WUA4
PVNIAPPECSTVVST	UBXN10	6	Q96LJ8
PAPEVCAALNVTVSP	VSTM4	16	Q8IW00
PSPPVARAAPVCETV	WASF1	396	Q92558
DIPVFTAAAAATPVP	TARBP2	121	Q15633
ATSSPPTPTCEAHLV	ZNF831	1051	Q5JPB2
PPSPTDVAKSNTAVC	ARHGAP21	251	Q5T5U3
STSQVPSIATVPPCL	ARHGAP21	831	Q5T5U3
CATPPGATVASVPLS	MST1R	736	Q04912
VPLPPICSNSTVHSE	XRRA1	521	Q6P2D8
TSAAADPPPEDCVTT	USP5	716	P45974
CAFEIPVPSSPISAS	USP6	791	P35125
AALSCSPRPTPAVVH	TNS2	1301	Q63HR2
PVTTSPLPAETDICL	ZFYVE9	866	O95405
TPTTAEACSPSPAVQ	ZBTB40	206	Q9NUA8
ACKTATPVSAPPDTT	ZSWIM4	651	Q9H7M6
CGPSPPCITTVSVNE	KRT81	71	Q14533