Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	NUDT12 DBR1 DICER1	1.68e-04	37	58	3	GO:0016891
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	NUDT12 DBR1 DICER1	3.23e-04	46	58	3	GO:0016893
Domain	Znf_C3HC4_RING-type	TRIM46 PCGF1 RNF213 ZNRF4	1.88e-03	172	57	4	IPR018957
Domain	zf-C3HC4	TRIM46 PCGF1 RNF213 ZNRF4	4.77e-03	223	57	4	PF00097
Pubmed	Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.	SYCP2L FADS1 LCT	1.64e-05	29	59	3	21829377
Pubmed	Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.	UIMC1 CCNDBP1 CFAP52 DNAH10	5.65e-05	122	59	4	31615875
Pubmed	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	UIMC1 SYCP2L	1.01e-04	9	59	2	19448621
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF136 ZNF142	3.79e-04	17	59	2	7557990
Pubmed	Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.	UIMC1 SYCP2L	4.75e-04	19	59	2	22267201
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	UIMC1 ZNF136 PCGF1 WIZ BAZ2A NSL1	5.72e-04	608	59	6	36089195
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	EFR3B CNOT1 DICER1	7.07e-04	102	59	3	10231032
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	UIMC1 NUDT12 PHYKPL ZNF136 CCNDBP1 SELENBP1 TEX264 TBC1D7 PTPN23	8.11e-04	1477	59	9	31515488
Pubmed	Whole-genome sequencing reveals host factors underlying critical COVID-19.	TRIM46 TYK2	8.28e-04	25	59	2	35255492
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	MRPS7 WIZ BAZ2A DICER1	8.83e-04	251	59	4	28077445
Pubmed	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	TYK2 FADS1 LBH	9.27e-04	112	59	3	24390342
Pubmed	Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.	FADS1 TERB1	1.12e-03	29	59	2	38485951
Pubmed	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	FADS1 B3GNT7	1.44e-03	33	59	2	23583979
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	UIMC1 MRPS7 CCP110 FADS1 TEX264 TBC1D7 LSM2 DICER1	1.47e-03	1293	59	8	15342556
Interaction	ANKH interactions	FAM234B SELENBP1 ENPP4	1.27e-05	17	55	3	int:ANKH
Interaction	CLSTN2 interactions	TYK2 NUP37 APBA3	2.86e-05	22	55	3	int:CLSTN2
Cytoband	15q14-q15	CCNDBP1 RYR3	1.62e-05	5	59	2	15q14-q15
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	TYK2 SEMA6B ZNF136 WIZ APBA3 ZNRF4	5.54e-04	797	59	6	chr19p13
Cytoband	19p13.3	SEMA6B APBA3 ZNRF4	3.57e-03	237	59	3	19p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr6p24	SYCP2L TBC1D7	3.71e-03	70	59	2	chr6p24
GeneFamily	Beta 3-glycosyltransferases	CHSY3 B3GNT7	1.15e-03	24	38	2	426
GeneFamily	Ring finger proteins	TRIM46 PCGF1 RNF213 ZNRF4	2.57e-03	275	38	4	58
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PHYKPL LBH NSL1 DBR1 LSM2	5.44e-06	191	59	5	6e1d00404d795ec7cf60f685e42e4ad9a16ac596
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	SELENBP1 CFAP52 DNAH10 ATP2C2 RYR3	5.44e-06	191	59	5	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PHYKPL LBH NSL1 DBR1 LSM2	5.44e-06	191	59	5	f158e393976b685b896a41871bda1ab65a8b58f5
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	SELENBP1 CFAP52 DNAH10 ATP2C2 RYR3	5.44e-06	191	59	5	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CCP110 ZNF136 DNAH10 CRY1	1.03e-04	184	59	4	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CFAP52 RNF213 B3GNT7 ENPP4	1.06e-04	185	59	4	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	Healthy_Control-Epithelial-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	15b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	Healthy_Control-Epithelial-Epithelial-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	28caedb2e448e0c7f494100d714fa7cdcf150691
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	b4e335e798c9617356b8e24412f9270c42dce656
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	Healthy_Control-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	Control-Epithelial-Ciliated\|Control / Disease group,lineage and cell class （2021.01.30）	SELENBP1 CFAP52 DNAH10 ATP2C2	1.19e-04	191	59	4	cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCell	severe-dn_T\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LBH SPINK9 LSM2 LCT	1.37e-04	198	59	4	d4f2213af45ada47e6c62675f468ce05692db507
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	1ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell	BAL-Mild-Epithelial-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	1df69c0cb5f759f6a2152521842506a75bb95cae
ToppCell	Mild-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCell	Mild-Epithelial-Epithelial-\|Mild / Condition, Lineage, Cell class and cell subclass	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	81115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCell	Mild-Epithelial-Epithelial\|Mild / Condition, Lineage, Cell class and cell subclass	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	91308b255783ad4029e5575028c18d7550832c51
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	74087b4b5e567310fc4ac58fb267ff651a180680
ToppCell	Mild_COVID-19-Epithelial\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	72689bda7476930887ae007682fcab27f956f050
ToppCell	BAL-Mild-Epithelial\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENBP1 CFAP52 DNAH10 ATP2C2	1.40e-04	199	59	4	00b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	CCP110 ZNF136 DNAH10 CRY1	1.42e-04	200	59	4	118321ac443feb42aee171baccfc4610f00a8822
Disease	phosphatidate measurement	FADS1 MMD	3.66e-04	15	56	2	EFO_0020047
Disease	alpha-linolenic acid measurement	FADS1 LCT	1.03e-03	25	56	2	EFO_0007759
Disease	docosapentaenoic acid measurement	SYCP2L FADS1	1.20e-03	27	56	2	EFO_0006809
Disease	abdominal:gluteofemoral adipose tissue ratio measurement	DNAH10 EFR3B	1.39e-03	29	56	2	EFO_0803320
Disease	eicosapentaenoic acid measurement	SYCP2L FADS1	1.59e-03	31	56	2	EFO_0007760
Disease	phosphatidylcholine 38:5 measurement	FADS1 DICER1	1.80e-03	33	56	2	EFO_0010387
Disease	triacylglycerol 56:6 measurement	FADS1 ATP2C2	3.04e-03	43	56	2	EFO_0010433
Disease	cholesteryl ester 20:5 measurement	SYCP2L FADS1	3.18e-03	44	56	2	EFO_0010349

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKLNQPASLYCPHMV	ACSM6	421	Q6P461
RSCPGNYPMQHERKV	LINC00303	106	Q3SY05
CHIYCHRPKMEAVPE	BAZ2A	1701	Q9UIF9
PAPQDHGRRLYKMLC	APBA3	316	O96018
YGAQPVRPEMLKHCA	ASB16	346	Q96NS5
PRCMFDHPDADKTLN	DICER1	1646	Q9UPY3
KYCCSPKRVQMHPED	ATP2C2	931	O75185
DHPNPAMAYANEVKR	PHYKPL	181	Q8IUZ5
LDAYSHIPPQLMEKC	PTPN23	411	Q9H3S7
KYDPDPAPHMENLKC	NSL1	161	Q96IY1
RLCMLYHPDKHRDPE	DNAJC11	36	Q9NVH1
CKMCRPRAYIFSDPH	FAM86B2	176	P0C5J1
TDPEKYPHMLSVKNC	LSM2	46	Q9Y333
KKLPPGQQRFCHHMY	SPINK9	36	Q5DT21
PIHCPDYLRSAKMTE	LBH	6	Q53QV2
RYLPNQDCLEGKIMH	FRMD7	146	Q6ZUT3
KCHPDQEHMIYPLGC	CFAP52	31	Q8N1V2
AICNPLHYPDLMSRK	OR2T7	116	P0C7T2
NHSIPVYEMKFPDLC	EFR3B	801	Q9Y2G0
NCSPHMNVYLKEDIP	ENPP4	286	Q9Y6X5
YRAPCHMKETPATSA	FAM234B	471	A2RU67
AGDKDMYVCHQPLPT	LCT	56	P09848
SYPQNKRPVHMDRAC	NUP37	241	Q8NFH4
MNHRAPANGRYKPTC	MMD	11	Q15546
ADLCYPFHGPAQMKV	CRHBP	261	P24387
YPPMCHLTVRINSAK	CCNDBP1	296	O95273
YPKPMVNHAEASRLN	CRY1	466	Q16526
TPYLMLCQPHKRCGD	IGFL1	31	Q6UW32
VPDTRSKMCLQKHYP	GALNTL5	116	Q7Z4T8
SKMCLQKHYPARLPT	GALNTL5	121	Q7Z4T8
MPKLHEPYASSQCIA	CCP110	501	O43303
AKPNCFRKDPDINMH	FADS1	221	O60427
IYMAIEHSPNKCLPV	FOXN2	121	P32314
EADLRCMAVPPKYRH	DBR1	46	Q9UK59
HCRYFPMLLNHPEKC	B3GNT7	116	Q8NFL0
PMLLNHPEKCRGDVY	B3GNT7	121	Q8NFL0
YFKISHEMLDQCPHP	DNAH10	4001	Q8IVF4
YCPMCNIKIHETQPL	PCGF1	81	Q9BSM1
VAICNPLHYDVVMKP	OR1L6	161	Q8NGR2
PYTIFHQALKNCEPM	MRPS7	141	Q9Y2R9
CQEMYKQPLVLPCTH	TRIM46	36	Q7Z4K8
YCQVIHRLPMPNLKD	SELENBP1	56	Q13228
KQRHENCYFLHPPMP	NUDT12	241	Q9BQG2
DPAMALKHEERKCPY	WIZ	691	O95785
HLRMCSAAPKLPYDL	TBC1D7	191	Q9P0N9
PSCPTARMLDDLHKY	SANBR	476	Q6NSI8
QCLDCRLMYPPHKFV	SKI	246	P12755
VHCDPNLDPKQYKMC	CHSY3	836	Q70JA7
PAANPTMIRAKCYHN	CNOT1	1921	A5YKK6
IAACNPYRKHSEEMI	RNF213	2521	Q63HN8
DNISGMARCPYDPKH	SEMA6B	166	Q9H3T3
MARCPYDPKHANVAL	SEMA6B	171	Q9H3T3
RHMLTHAEDGPPYKC	ZNF136	521	P52737
CVLCKQPRHGAPMYR	SLC35B2	171	Q8TB61
NFCPDHKAPMVLFLD	RYR3	2356	Q15413
HKKYDPDLFRMALPC	RYR3	2551	Q15413
PCIAAFADEHEMRKP	SYCP2L	296	Q5T4T6
GYLMEVKPANACHPI	ZNRF4	131	Q8WWF5
YDNPHMVPPDKCRCA	TEX264	81	Q9Y6I9
PYACADPSRLKYHMR	ZNF142	1486	P52746
MKTPLKSANPVHACY	TERB1	491	Q8NA31
CFPPTKIERHAMYCN	UIMC1	511	Q96RL1
RPDKCPCEVYHLMKN	TYK2	1136	P29597