Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA helicase activity

YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

1.24e-05781316GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity

KIF21A SMARCAL1 KIF1B YTHDC2 DHX33 ATAD2 ATP13A2 DDX5 DHX30 ATP6V1D DHX35 DDX60L KIF18B KIF17 SLC27A4

1.24e-0561413115GO:0140657
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

1.43e-05801316GO:0008186
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21A KIF1B YTHDC2 DHX33 ATAD2 ATP13A2 DDX5 DHX30 DHX35 DDX60L KIF18B KIF17

3.44e-0544113112GO:0016887
GeneOntologyMolecularFunctionhelicase activity

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

8.35e-051581317GO:0004386
GeneOntologyMolecularFunctionpyrophosphatase activity

PRUNE2 KIF21A KIF1B YTHDC2 DHX33 ATAD2 ATP13A2 DDX5 DHX30 GNA11 DHX35 DDX60L GNAQ KIF18B KIF17 SEPTIN12

1.24e-0483913116GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PRUNE2 KIF21A KIF1B YTHDC2 DHX33 ATAD2 ATP13A2 DDX5 DHX30 GNA11 DHX35 DDX60L GNAQ KIF18B KIF17 SEPTIN12

1.25e-0484013116GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PRUNE2 KIF21A KIF1B YTHDC2 DHX33 ATAD2 ATP13A2 DDX5 DHX30 GNA11 DHX35 DDX60L GNAQ KIF18B KIF17 SEPTIN12

1.25e-0484013116GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF21A KIF1B YTHDC2 DHX33 ATAD2 ATP13A2 DDX5 DHX30 GNA11 DHX35 DDX60L GNAQ KIF18B KIF17 SEPTIN12

1.74e-0477513115GO:0017111
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF1B KIF18B KIF17

1.75e-04171313GO:0008574
GeneOntologyMolecularFunctionalkylglycerophosphoethanolamine phosphodiesterase activity

GNA11 GNAQ

4.22e-0451312GO:0047391
GeneOntologyMolecularFunctionactivin receptor activity, type I

ACVR1B ACVRL1

4.22e-0451312GO:0016361
GeneOntologyMolecularFunctionkinesin binding

KIF1B IFT88 KIF18B CROCC

4.66e-04551314GO:0019894
GeneOntologyMolecularFunctiongrowth factor binding

RHBDF1 ITGA6 ACVR1B ACVRL1 ITGB4 KDR

5.78e-041561316GO:0019838
GeneOntologyMolecularFunctionneuregulin binding

ITGA6 ITGB4

6.30e-0461312GO:0038132
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF21A KIF1B KIF18B KIF17

1.16e-03701314GO:0003777
GeneOntologyMolecularFunctionnuclear androgen receptor binding

PRPF6 KDM5D DDX5

1.30e-03331313GO:0050681
GeneOntologyMolecularFunctionactivin receptor activity

ACVR1B ACVRL1

1.49e-0391312GO:0017002
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

PLXNA3 CUX2 DOCK11 OBSL1 ITGA6 EPS8L1 TENM2 CDC42EP1 METRN IFT88 ROBO2 CROCC PLXNB1

1.37e-0549412913GO:0031346
DomainDUF1605

YTHDC2 DHX33 DHX30 DHX35

4.53e-06171274IPR011709
DomainOB_NTP_bind

YTHDC2 DHX33 DHX30 DHX35

4.53e-06171274PF07717
DomainHA2

YTHDC2 DHX33 DHX30 DHX35

5.79e-06181274SM00847
DomainHA2

YTHDC2 DHX33 DHX30 DHX35

5.79e-06181274PF04408
DomainHelicase-assoc_dom

YTHDC2 DHX33 DHX30 DHX35

5.79e-06181274IPR007502
DomainHelicase_C

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

8.45e-061071277PF00271
DomainHELICc

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

8.45e-061071277SM00490
DomainHelicase_C

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

8.98e-061081277IPR001650
DomainHELICASE_CTER

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

9.55e-061091277PS51194
DomainHELICASE_ATP_BIND_1

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

9.55e-061091277PS51192
DomainDEXDc

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

9.55e-061091277SM00487
DomainHelicase_ATP-bd

SMARCAL1 YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

1.01e-051101277IPR014001
DomainDEAD/DEAH_box_helicase_dom

YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

1.03e-05731276IPR011545
DomainDEAD

YTHDC2 DHX33 DDX5 DHX30 DHX35 DDX60L

1.03e-05731276PF00270
DomainP-loop_NTPase

MTHFD1L KIF21A SMARCAL1 KIF1B YTHDC2 DHX33 IQCN ATAD2 DDX5 DHX30 HS3ST6 GNA11 DHX35 DDX60L GNAQ KIF18B KIF17 SEPTIN12

1.73e-0584812718IPR027417
DomainDEAH_ATP_HELICASE

YTHDC2 DHX33 DHX30 DHX35

1.26e-04381274PS00690
DomainKinesin_motor_CS

KIF21A KIF1B KIF18B KIF17

1.70e-04411274IPR019821
DomainKinesin-like_fam

KIF21A KIF1B KIF18B KIF17

2.05e-04431274IPR027640
Domain-

KIF21A KIF1B KIF18B KIF17

2.24e-044412743.40.850.10
DomainKinesin

KIF21A KIF1B KIF18B KIF17

2.24e-04441274PF00225
DomainKISc

KIF21A KIF1B KIF18B KIF17

2.24e-04441274SM00129
DomainKINESIN_MOTOR_1

KIF21A KIF1B KIF18B KIF17

2.24e-04441274PS00411
DomainKinesin_motor_dom

KIF21A KIF1B KIF18B KIF17

2.24e-04441274IPR001752
DomainKINESIN_MOTOR_2

KIF21A KIF1B KIF18B KIF17

2.24e-04441274PS50067
DomainPSI

PLXNA3 ITGB4 PLXDC2 PLXNB1

2.24e-04441274IPR016201
DomainPSI

PLXNA3 ITGB4 PLXDC2 PLXNB1

2.67e-04461274SM00423
DomainNeural_cell_adh

HMCN1 ROBO2

2.73e-0441272IPR009138
DomainGprotein_alpha_Q

GNA11 GNAQ

2.73e-0441272IPR000654
DomainIg_I-set

MXRA5 OBSL1 IGDCC3 FCRL1 HMCN1 ROBO2 KDR

3.23e-041901277IPR013098
DomainI-set

MXRA5 OBSL1 IGDCC3 FCRL1 HMCN1 ROBO2 KDR

3.23e-041901277PF07679
Domain-

PLXNA3 MXRA5 MYCBP2 HLA-DQB2 OBSL1 IGDCC3 PTGFRN ITGB4 FCRL1 HMCN1 ROBO2 KDR PLXNB1

5.87e-04663127132.60.40.10
DomainAPC_su10/DOC_dom

MYCBP2 HERC2

9.42e-0471272IPR004939
DomainGS_dom

ACVR1B ACVRL1

9.42e-0471272IPR003605
DomainGS

ACVR1B ACVRL1

9.42e-0471272PS51256
DomainDOC

MYCBP2 HERC2

9.42e-0471272PS51284
DomainTGF_beta_GS

ACVR1B ACVRL1

9.42e-0471272PF08515
DomainANAPC10

MYCBP2 HERC2

9.42e-0471272PF03256
DomainGS

ACVR1B ACVRL1

9.42e-0471272SM00467
DomainAPC10

MYCBP2 HERC2

9.42e-0471272SM01337
DomainIg-like_fold

PLXNA3 MXRA5 MYCBP2 HLA-DQB2 OBSL1 IGDCC3 PTGFRN ITGB4 FCRL1 HMCN1 ROBO2 KDR PLXNB1

1.05e-0370612713IPR013783
DomainIGc2

MXRA5 OBSL1 IGDCC3 FCRL1 HMCN1 ROBO2 KDR

1.14e-032351277SM00408
DomainIg_sub2

MXRA5 OBSL1 IGDCC3 FCRL1 HMCN1 ROBO2 KDR

1.14e-032351277IPR003598
DomainPlexin_repeat

PLXNA3 PLXDC2 PLXNB1

1.32e-03321273IPR002165
DomainPSI

PLXNA3 PLXDC2 PLXNB1

1.32e-03321273PF01437
DomainPlexin_cytopl

PLXNA3 PLXNB1

1.60e-0391272PF08337
DomainR3H

R3HCC1 YTHDC2

1.60e-0391272SM00393
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNB1

1.60e-0391272IPR013548
DomainPlexin

PLXNA3 PLXNB1

1.60e-0391272IPR031148
DomainDNA/RNA_helicase_DEAH_CS

DHX33 DHX30 DHX35

1.71e-03351273IPR002464
Domain-

MTHFD1L SMARCAL1 YTHDC2 DHX33 ATAD2 DDX5 DHX30 HS3ST6 GNA11 DHX35 DDX60L GNAQ SEPTIN12

1.71e-03746127133.40.50.300
DomainR3H

R3HCC1 YTHDC2

2.42e-03111272PS51061
DomainR3H

R3HCC1 YTHDC2

2.42e-03111272PF01424
Domain-

R3HCC1 YTHDC2

2.42e-031112723.30.1370.50
DomainR3H_dom

R3HCC1 YTHDC2

2.42e-03111272IPR001374
DomainPDZ

IL16 FRMPD2 MPDZ LNX1 ARHGAP21

2.78e-031411275PF00595
DomainTGFB_receptor

ACVR1B ACVRL1

2.90e-03121272IPR000333
DomainRho_GTPase_activation_prot

PLXNA3 ARHGAP11A ARHGAP21 PLXNB1

3.06e-03881274IPR008936
DomainPDZ

IL16 FRMPD2 MPDZ LNX1 ARHGAP21

3.42e-031481275SM00228
Domain-

IL16 FRMPD2 MPDZ LNX1 ARHGAP21

3.63e-0315012752.30.42.10
DomainPDZ

IL16 FRMPD2 MPDZ LNX1 ARHGAP21

3.73e-031511275PS50106
DomainPDZ

IL16 FRMPD2 MPDZ LNX1 ARHGAP21

3.84e-031521275IPR001478
DomainGproteinA_insert

GNA11 GNAQ

5.17e-03161272IPR011025
Domain-

GNA11 GNAQ

5.17e-031612721.10.400.10
DomainG-alpha

GNA11 GNAQ

5.17e-03161272PF00503
DomainG_alpha

GNA11 GNAQ

5.17e-03161272SM00275
DomainCarboxyPept-like_regulatory

CPD TENM2

5.84e-03171272IPR008969
DomainGprotein_alpha_su

GNA11 GNAQ

5.84e-03171272IPR001019
DomainPBD

CDC42BPG CDC42EP1

5.84e-03171272PF00786
DomainIG_LIKE

MXRA5 HLA-DQB2 OBSL1 IGDCC3 PTGFRN FCRL1 HMCN1 ROBO2 KDR

6.41e-034911279PS50835
DomainRasGAP_dom

PLXNA3 PLXNB1

6.54e-03181272IPR001936
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DPYSL2 MYCBP2 MTHFD1L RPS5 AHCTF1 KIF21A TAF1C RPS9 ELP1 PRPF6 DHX33 ATAD2 EIF6 DDX5 DHX30 KANSL1 GTF3C1 GEMIN4 DLAT DDX60L HERC2 KIF18B PHIP SLC27A4

3.37e-1013531332429467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DPYSL2 MYCBP2 MTHFD1L RPS5 AHCTF1 UGGT1 ELP1 YTHDC2 PRPF6 ATAD2 EIF6 DHX30 GTF3C1 GEMIN4 DLAT HERC2 PHIP

5.97e-106531331722586326
Pubmed

Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling.

KDR GNA11 GNAQ

5.47e-083133312670961
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MYCBP2 DOCK11 RPS5 ELP1 YTHDC2 PRPF6 DHX30 RPS6KC1 GTF3C1 DHX35 HERC2 ESPL1

1.40e-074401331234244565
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 NDOR1 RHBDF1 MYCBP2 MTHFD1L WNT7B LAD1 PSMB10 GRB10 ATP13A2 ITGB4 EIF6 DHX30 KANSL1 HERC2 ESPL1 ARHGAP21 GAREM1

2.41e-0711051331835748872
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

MTHFD1L RPS5 SMARCAL1 RPS9 PRPF6 DDX5 DHX30 SUN2 GEMIN4 ATXN10 HERC2

2.85e-073831331129331416
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CDC42BPG DPYSL2 MXRA5 DOCK11 NACC1 KIF21A RPS9 IGDCC3 PIWIL2 ACVR1B ARHGAP11A DDX5 RPS6KC1 GTF3C1

9.62e-077361331429676528
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MYCBP2 RPS5 RPS9 YTHDC2 PRPF6 DHX33 EIF6 DDX5 DHX30 GTF3C1 DLAT HERC2 ESPL1 SAP130

1.38e-067591331435915203
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

MYCBP2 DOCK11 KIF1B ITGA6 DDX5 HERC2

1.52e-0692133615840729
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

RPS5 RPS9 HDX EI24 ELP1 CPD DDX5 SUN2 GEMIN4 DLAT ATXN10 HERC2 SLC27A4

1.56e-066571331336180527
Pubmed

Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization.

ITGA6 PTGFRN ITGB4

1.89e-067133316537545
Pubmed

Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development.

ACVR1B ACVRL1 KDR

1.89e-067133316344855
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

DPYSL2 MYCBP2 NACC1 RPS5 ACTR10 UGGT1 RPS9 MRPS35 MPDZ PRPF6 EIF6 CYFIP2 DDX5 GTF3C1 GEMIN4 DLAT ATXN10

1.99e-0611491331735446349
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DPYSL2 ACTR8 MYCBP2 KIF21A TAF1C SPTB KIF1B OBSL1 MRPS35 DHX30 IFT88 ARIH2 DLAT DHX35 ATXN10 HERC2 LNX1 ARHGAP21

2.09e-0612851331835914814
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MTHFD1L RPS5 UGGT1 RPS9 ELP1 MRPS35 YTHDC2 PRPF6 ATAD2 EIF6 CYFIP2 DDX5 DHX30 GTF3C1 GEMIN4 DLAT ATXN10 PHIP SLC27A4

2.18e-0614251331930948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DPYSL2 IL16 PDK1 RPS5 SPTB KIF1B RPS9 ELP1 YTHDC2 CYFIP2 DDX5 DHX30 SPON1 ATP6V1D DLAT C1QB GNAQ CROCC ARHGAP21

2.32e-0614311331937142655
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MYCBP2 PDK1 MTHFD1L AHCTF1 UGGT1 OBSL1 ELP1 MRPS35 MPDZ CPD PRPF6 EIF6 DHX30 CDC42EP1 SUN2 DLAT ATXN10 HERC2 ESPL1

4.04e-0614871331933957083
Pubmed

Phospho-tyrosine dependent protein-protein interaction network.

SPTB OBSL1 GRB10 TENT5B DDX5 HROB ASB8 SOCS1 LNX1 GAREM1

4.33e-064101331025814554
Pubmed

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth.

DPYSL2 ITGA6 ITGB4 DDX5 ATP6V1D KCNK1 DLAT

4.37e-06170133736470425
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DPYSL2 MTHFD1L UGGT1 OBSL1 ELP1 MRPS35 MPDZ YTHDC2 CPD PTPN21 GTF3C1 GEMIN4 ATXN10 ESPL1 SLC27A4

5.16e-069741331528675297
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

AHCTF1 YTHDC2 DHX33 ATAD2 EIF6 DHX30 SUN2 DDX60L PHIP

5.70e-06332133925693804
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPS5 AHCTF1 UGGT1 LAD1 RPS9 ITGA6 MRPS35 YTHDC2 PRPF6 ARHGAP11A ITGB4 EIF6 DDX5 DHX30 GTF3C1 SUN2 GEMIN4

6.53e-0612571331736526897
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CDC42BPG EI24 OBSL1 ELP1 MPDZ YTHDC2 GTF3C1 AP5B1 STARD3 ARHGAP21 PLXNB1 SLC27A4

8.06e-066501331238777146
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

CUX2 MXRA5 AHCTF1 EPS8L1 ATAD2 EIF6 CYFIP2 DDX5 PROM1 ATP6V1D GEMIN4 ROBO2 GNA11 GNAQ CROCC

8.52e-0610161331519056867
Pubmed

Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis.

NDOR1 ITGA6 ITGB4

8.82e-0611133335941116
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MYCBP2 RPS5 UGGT1 RPS9 OBSL1 ELP1 YTHDC2 PRPF6 EIF6 DDX5 DHX30 GTF3C1 ATXN10 HERC2 PHIP

9.35e-0610241331524711643
Pubmed

Integral and associated lysosomal membrane proteins.

ATP13A2 AP5B1 ATP6V1D STARD3 GNA11 GNAQ

9.44e-06126133617897319
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PLXNA3 CUX2 RPS5 KIF21A UGGT1 MRPS35 SIK1 PRPF6 PTPN21 CYFIP2 DDX5 RPS6KC1 GTF3C1 IFT88 DLAT KDR ARHGAP21 SLC27A4

1.02e-0514421331835575683
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

DPYSL2 PDK1 MTHFD1L UGGT1 ELP1 CPD PRPF6 DLAT DHX35 ATXN10 SAP130

1.10e-055601331135241646
Pubmed

Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.

ITGA6 ITGB4 KDR

1.17e-0512133311381080
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

MYCBP2 PDK1 EI24 OBSL1 SAV1 TENM2 DHX30 XYLT2 GTF3C1 STARD3

1.22e-054621331031138677
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF21A KIF1B KIF18B KIF17

1.22e-0537133411416179
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

DOCK11 NACC1 MTHFD1L ACTR10 UGGT1 SAV1 ELP1 MRPS35 PTPN21 GEMIN4 DLAT GNA11 ATXN10 SLC27A4

1.41e-059311331427432908
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

CDC42BPG UGGT1 OBSL1 ELP1 YTHDC2 EIF6 DHX30 PLXDC2

1.42e-05283133821903422
Pubmed

The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.

GNA11 GNAQ

1.45e-052133228248732
Pubmed

Activation of Gq/11 in the mouse corpus luteum is required for parturition.

GNA11 GNAQ

1.45e-052133225495873
Pubmed

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

ITGA6 ITGB4

1.45e-052133215731010
Pubmed

Lethal junctional epidermolysis bullosa with pyloric atresia due to compound heterozygosity for two novel mutations in the integrin β4 gene.

ITGA6 ITGB4

1.45e-052133221969027
Pubmed

Epidermal α6β4 integrin stimulates the influx of immunosuppressive cells during skin tumor promotion.

ITGA6 ITGB4

1.45e-052133222464766
Pubmed

Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.

GNA11 GNAQ

1.45e-052133221945171
Pubmed

Phenotypic spectrum of epidermolysis bullosa associated with α6β4 integrin mutations.

ITGA6 ITGB4

1.45e-052133223496044
Pubmed

Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.

GNA11 GNAQ

1.45e-05213329175863
Pubmed

PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport.

PLIN5 SLC27A4

1.45e-052133237290445
Pubmed

Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily.

ITGA6 ITGB4

1.45e-05213322475502
Pubmed

The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.

GNA11 GNAQ

1.45e-052133228083870
Pubmed

Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.

GNA11 GNAQ

1.45e-052133226843449
Pubmed

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.

GNA11 GNAQ

1.45e-052133230890659
Pubmed

Integrin alpha 6 is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex.

ITGA6 ITGB4

1.45e-052133235657344
Pubmed

Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.

GNA11 GNAQ

1.45e-05213329607776
Pubmed

Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.

GNA11 GNAQ

1.45e-052133231726051
Pubmed

G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.

GNA11 GNAQ

1.45e-052133211438569
Pubmed

GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.

GNA11 GNAQ

1.45e-052133237802294
Pubmed

Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.

GNA11 GNAQ

1.45e-052133226628681
Pubmed

The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.

GNA11 GNAQ

1.45e-052133217552882
Pubmed

Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma.

ACVRL1 KDR

1.45e-052133227248821
Pubmed

Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.

GNA11 GNAQ

1.45e-052133231173078
Pubmed

Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.

GNA11 GNAQ

1.45e-052133229209985
Pubmed

Integrin alpha6 maintains the structural integrity of the kidney collecting system.

ITGA6 ITGB4

1.45e-052133228043890
Pubmed

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

ITGA6 ITGB4

1.45e-05213322542022
Pubmed

Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.

GNA11 GNAQ

1.45e-052133215175381
Pubmed

Dynamics of the alpha6beta4 integrin in keratinocytes.

ITGA6 ITGB4

1.45e-052133212429829
Pubmed

Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.

GNA11 GNAQ

1.45e-052133225280020
Pubmed

GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.

GNA11 GNAQ

1.45e-052133227498141
Pubmed

A key tyrosine (Y1494) in the beta4 integrin regulates multiple signaling pathways important for tumor development and progression.

ITGA6 ITGB4

1.45e-052133218974120
Pubmed

Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression.

ITGA6 ITGB4

1.45e-052133216258729
Pubmed

Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.

GNA11 GNAQ

1.45e-052133228982892
Pubmed

Mutations in GNA11 in uveal melanoma.

GNA11 GNAQ

1.45e-052133221083380
Pubmed

HPV16 infection of HaCaTs is dependent on β4 integrin, and α6 integrin processing.

ITGA6 ITGB4

1.45e-052133224418536
Pubmed

GNAQ and GNA11 mutations in uveal melanoma.

GNA11 GNAQ

1.45e-052133225304237
Pubmed

Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.

GNA11 GNAQ

1.45e-052133228301547
Pubmed

α6β4 Integrin Regulates the Collective Migration of Epithelial Cells.

ITGA6 ITGB4

1.45e-052133227922761
Pubmed

Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.

GNA11 GNAQ

1.45e-052133216847339
Pubmed

The 3'UTR of the α6 integrin message regulates localization of α6β4 integrin heterodimers.

ITGA6 ITGB4

1.45e-052133230922568
Pubmed

Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.

GNA11 GNAQ

1.45e-052133229570931
Pubmed

Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.

GNA11 GNAQ

1.45e-052133210818132
Pubmed

Human osteosarcoma CD49f(-)CD133(+) cells: impaired in osteogenic fate while gain of tumorigenicity.

ITGA6 PROM1

1.45e-052133223045288
Pubmed

Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.

GNA11 GNAQ

1.45e-052133226272756
Pubmed

NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.

GNA11 GNAQ

1.45e-052133231461351
Pubmed

Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.

GNA11 GNAQ

1.45e-052133223634288
Pubmed

Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.

GNA11 GNAQ

1.45e-052133226368812
Pubmed

Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.

GNA11 GNAQ

1.45e-052133217482476
Pubmed

Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin alpha(6).

ITGA6 KDR

1.45e-052133217979890
Pubmed

Curcumin inhibition of the functional interaction between integrin α6β4 and the epidermal growth factor receptor.

ITGA6 ITGB4

1.45e-052133221388972
Pubmed

Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.

GNA11 GNAQ

1.45e-052133224141786
Pubmed

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.

ITGA6 ITGB4

1.45e-05213321976638
Pubmed

Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells.

ITGB4 EIF6

1.45e-05213329374518
Pubmed

Alpha 6 beta 4 integrin abnormalities in junctional epidermolysis bullosa with pyloric atresia.

ITGA6 ITGB4

1.45e-052133211251584
Pubmed

α6β4 Integrin Genetic Variations (A380T and R1281W) and Breast Cancer Risk in an Argentinian Population.

ITGA6 ITGB4

1.45e-052133227763564
Pubmed

Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.

GNA11 GNAQ

1.45e-052133237102682
Pubmed

α6β4 integrin, a master regulator of expression of integrins in human keratinocytes.

ITGA6 ITGB4

1.45e-052133222493440
Pubmed

Developmentally regulated expression of the beta 4 integrin on immature mouse thymocytes.

ITGA6 ITGB4

1.45e-05213321385605
Pubmed

Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways.

GNA11 GNAQ

1.45e-05213327492305
Pubmed

Reduced trabecular bone mass and strength in mice overexpressing Gα11 protein in cells of the osteoblast lineage.

GNA11 GNAQ

1.45e-052133224308950
Pubmed

Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.

GNA11 GNAQ

1.45e-052133222562663
Pubmed

Molecular cloning of the human alpha 6 integrin subunit. Alternative splicing of alpha 6 mRNA and chromosomal localization of the alpha 6 and beta 4 genes.

ITGA6 ITGB4

1.45e-05213322070796
Pubmed

Expression of the beta 4 integrin subunit in the mouse heart during embryonic development: retinoic acid advances beta 4 expression.

ITGA6 ITGB4

1.45e-05213328875079
Pubmed

Integrin beta4 signaling promotes tumor angiogenesis.

ITGA6 ITGB4

1.45e-052133215542431
Pubmed

Functional specificity of G alpha q and G alpha 11 in the cholinergic and glutamatergic modulation of potassium currents and excitability in hippocampal neurons.

GNA11 GNAQ

1.45e-052133211826096
Pubmed

Blue nevi and variants: an update.

GNA11 GNAQ

1.45e-052133221366456
Pubmed

In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.

GNA11 GNAQ

1.45e-052133235580369
InteractionSIRT7 interactions

DPYSL2 MYCBP2 MTHFD1L RPS5 AHCTF1 UGGT1 ELP1 YTHDC2 PRPF6 ATAD2 EIF6 DHX30 GTF3C1 GEMIN4 DLAT HERC2 PHIP

4.89e-0674412817int:SIRT7
InteractionEED interactions

CDC42BPG ACTR8 MYCBP2 MTHFD1L RPS5 ACTR10 AHCTF1 UGGT1 RPS9 ELP1 PRPF6 DHX33 ATAD2 EIF6 DDX5 GTF3C1 SUN2 C1QB ATXN10 HERC2 KIF18B CROCC KIF17 SAP130

1.21e-05144512824int:EED
InteractionMYCBP2 interactions

MYCBP2 RPS5 ATP13A2 CYFIP2 ASB8 SPRYD3 C1QB ROBO2 HERC2 LNX1 ARHGAP21

1.68e-0535512811int:MYCBP2
Cytoband14q23-q24.2

SPTB ATP6V1D

2.49e-053133214q23-q24.2
GeneFamilyDEAH-box helicases

DHX33 DHX30 DHX35

4.65e-0516813500
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF21A KIF1B KIF18B KIF17

5.29e-0546814622
GeneFamilyPDZ domain containing

IL16 FRMPD2 MPDZ FRMPD2B LNX1 ARHGAP21

6.18e-051528161220
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MXRA5 OBSL1 IGDCC3 HMCN1 ROBO2 KDR

8.49e-05161816593
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

CDC42BPG DOCK11 SPTB KIF1B GRB10 ARHGAP21

3.24e-04206816682
GeneFamilyType 1 receptor serine/threonine kinases

ACVR1B ACVRL1

4.10e-047812345
GeneFamilyPlexins

PLXNA3 PLXNB1

6.99e-049812683
GeneFamilyImmunoglobulin like domain containing

MXRA5 OBSL1 PTGFRN FCRL1 KDR

1.75e-03193815594
GeneFamilyCadherin related

CDH23 FAT2

2.58e-031781224
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL

MTHFD1L IGDCC3 GRB10 ACVR1B ARHGAP11A ATAD2 TENT5B HROB PLXDC2 KIF18B CENATAC ESPL1 PCSK4

6.63e-0656713313M45692
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_1000

MYCBP2 PDK1 WNT7B LAD1 HIPK2 CPD EPS8L1 ATAD2 PROM1 FAT2 KANSL1 PLIN5 KCNK1 HERC2 LNX1 PLXNB1

2.02e-0578412816gudmap_developingLowerUrinaryTract_e15.5_urothelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#4

KIF21A WNT7B HIPK2 IGDCC3 TEX9 CYFIP2 PROM1

2.16e-051391287Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K4
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_1000

MYCBP2 PDK1 AHCTF1 WNT7B LAD1 RPS9 OBSL1 HIPK2 GRB10 EPS8L1 CYFIP2 KANSL1 KCNK1 HS3ST6 PLXNB1

7.97e-0578612815gudmap_developingKidney_e15.5_Medullary collecting duct_1000
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_500

HIPK2 ITGA6 GRB10 CPD KANSL1

8.50e-05741285gudmap_developingKidney_e15.5_S-shaped body_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

MYCBP2 KIF1B HIPK2 GRB10 CPD TEX9 ATAD2 TENM2 GREB1L PROM1 KANSL1 SPON1 KCNK1 HS3ST6 ROBO2

9.04e-0579512815gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A WNT7B LAD1 ITGB4 TENT5B FAT2 HS3ST6 PLXNB1

1.05e-071891338783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A WNT7B LAD1 ITGB4 TENT5B FAT2 HS3ST6 PLXNB1

1.05e-07189133888b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF21A WNT7B LAD1 ITGB4 TENT5B FAT2 HS3ST6 PLXNB1

1.09e-07190133847e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF21A WNT7B LAD1 ITGB4 TENT5B FAT2 HS3ST6 PLXNB1

1.09e-071901338261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 KIF21A UGGT1 KIF1B KDM5D CYFIP2 DDX5 ROBO2

1.33e-0719513383e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 KIF21A UGGT1 KIF1B KDM5D CYFIP2 DDX5 ROBO2

1.33e-0719513387796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OOEP PTGFRN KCNK1 NKPD1 C1QB CROCC ESPL1

5.86e-071621337b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT7B LAD1 ITGB4 TENT5B PROM1 FAT2 PLXNB1

1.48e-06186133737b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell(2)_Fibroblasts-(21)_Fibro-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PRUNE2 DPYSL2 HIPK2 ITGA6 CDH23 ROBO2 LNX1

1.76e-0619113375ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRUNE2 WNT7B EPS8L1 PTPN21 KCNK1 PLXNB1 GAREM1

1.83e-0619213378899d81306770adda893b5e146df1253971754c5
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRUNE2 WNT7B EPS8L1 PTPN21 KCNK1 PLXNB1 GAREM1

1.83e-0619213375fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

ITGA6 GRB10 HMCN1 PLXDC2 KDR GNAQ LNX1

2.02e-061951337fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

ITGA6 GRB10 HMCN1 PLXDC2 KDR GNAQ LNX1

2.17e-061971337f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DOCK11 WNT7B GREB1L PROM1 SPON1

3.57e-0613713360aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM13C HDX PIWIL2 ACVR1B TENT5B LNX1

1.11e-051671336cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MTHFD1L HLA-DQB2 WNT7B SIK1 METRN GNAQ

1.45e-051751336334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MTHFD1L HLA-DQB2 WNT7B ITGA6 SIK1 GNAQ

1.45e-051751336da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

CUX2 CDH23 ATP13A2 ITGB4 GNAQ RUFY4

1.50e-051761336d6e660df92a3d7dd5732171ee623763faf108476
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGDCC3 TTLL8 GREB1L METRN SPON1 HS3ST6

1.92e-0518413366b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGDCC3 TTLL8 GREB1L METRN SPON1 HS3ST6

1.92e-05184133635928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXRA5 LAD1 ITGA6 PTGFRN ITGB4 FAT2

1.98e-051851336e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT7B LAD1 ITGB4 TENT5B PROM1 FAT2

2.11e-051871336380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCelldroplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT7B LAD1 ITGB4 TENT5B PROM1 FAT2

2.11e-0518713365b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT7B LAD1 ITGB4 TENT5B PROM1 FAT2

2.11e-051871336796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

IL16 TENM2 HMCN1 PLXDC2 SPON1 ROBO2

2.11e-051871336bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT7B LAD1 ITGB4 TENT5B FAT2 PLXNB1

2.17e-0518813368ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT7B LAD1 ITGB4 TENT5B FAT2 PLXNB1

2.17e-051881336137ed9958044fab7a13648affb469585d1c48cf6
ToppCellIPF-Epithelial-Aberrant_Basaloid|World / Disease state, Lineage and Cell class

WNT7B LAD1 ITGB4 KCNK1 KDR PLXNB1

2.24e-0518913368030a353473da34ae92429f2d822171a2e94248f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RPS5 WNT7B IQCN GREB1L PROM1 SPON1

2.24e-0518913361ecf9911ff82e0ca0f0c101b735d3b1f3b339d57
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF21A WNT7B CPD EPS8L1 KCNK1 GAREM1

2.30e-0519013366ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

KIF21A SPTB KDM5D TENM2 KCNK1 GAREM1

2.30e-0519013363729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDK1 PRPF6 ANKH CCDC7 SOCS1 GNAQ

2.37e-0519113369bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPYSL2 ITGA6 ACVRL1 CDC42EP1 HMCN1 KDR

2.37e-05191133638fe60a8570f3c6eb8e8f8646f90d505dfd7d647
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT7B ITGA6 ITGB4 PROM1 KCNK1 HS3ST6

2.37e-051911336b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAD1 ITGA6 ARHGAP11A ITGB4 FAT2 KCNK1

2.37e-0519113360f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPYSL2 ITGA6 ACVRL1 CDC42EP1 HMCN1 KDR

2.37e-0519113360e6cd2628a5cebd35e960e4eb3b52ddc9358031c
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDOR1 KIF21A ITGB4 TENM2 FAT2 HS3ST6

2.37e-051911336ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 UGGT1 ANKH CYFIP2 HS3ST6 ROBO2

2.37e-051911336f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF21A WNT7B LAD1 GRB10 KCNK1 ATXN10

2.37e-0519113366f5d91a9583bbb30dfaa30dd9c7772995a9196be
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

ITGA6 GRB10 CDH23 PLXDC2 KDR LNX1

2.37e-051911336c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

WNT7B ITGA6 ARHGAP11A CYFIP2 KIF18B ESPL1

2.44e-05192133625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

ITGA6 GRB10 CDH23 PLXDC2 KDR LNX1

2.44e-0519213368a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 SIK1 ACVRL1 PROM1 HMCN1 KDR

2.44e-0519213369ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 SIK1 ACVRL1 PROM1 HMCN1 KDR

2.44e-051921336a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Lung-EPCAM-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A LAD1 ITGB4 FAT2 HS3ST6 PLXNB1

2.44e-05192133612096302a3a4d26e21ca04357aa557143f482155
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 SIK1 ACVRL1 PROM1 HMCN1 KDR

2.44e-05192133666defad13bd8e79319741e43ddb056841710b1d7
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

MTHFD1L HIPK2 GRB10 HMCN1 PLXDC2 GNAQ

2.52e-05193133601c2df9206f1527c578e808978e58196c35e72f5
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA6 GRB10 ACVRL1 HMCN1 KDR GNAQ

2.52e-051931336e1d546165dcc2392f540162206852c4717d7306f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL16 CDH23 TENM2 HMCN1 SPON1 ROBO2

2.52e-051931336b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

ITGA6 HMCN1 PLXDC2 KDR GNAQ LNX1

2.52e-051931336e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ITGB4 GREB1L FAT2 KCNK1 PLXNB1

2.59e-0519413363701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA6 ITGB4 GREB1L FAT2 KCNK1 PLXNB1

2.59e-05194133665f9bf126be26114c2c3f4c46d48318986212a92
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

MXRA5 MTHFD1L HMCN1 PLXDC2 SPON1 ROBO2

2.59e-05194133603a269f75a481ea54aea8e6444605db8d6df493d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 ITGA6 ITGB4 GREB1L KCNK1 GAREM1

2.59e-0519413364579b4a44f7c731553a284843c296866027d7c0e
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

ITGA6 HMCN1 PLXDC2 KDR GNAQ LNX1

2.59e-0519413367b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

MTHFD1L HIPK2 GRB10 ITGB4 HMCN1 PLXDC2

2.59e-051941336b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA6 GRB10 ACVRL1 HMCN1 ROBO2 KDR

2.59e-0519413360b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellPND07-28-samps-Mesenchymal|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DPYSL2 GRB10 HMCN1 PLXDC2 SPON1 ROBO2

2.59e-05194133668bcc1fe8dc8d5f23a12154fc9b41362fdef0b1d
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM13C ITGA6 ACVRL1 CDC42EP1 HMCN1 KDR

2.59e-0519413367f24023df47935286f185dd428d48797daf26f49
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

ITGA6 HMCN1 PLXDC2 KDR GNAQ LNX1

2.67e-05195133619e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCelldroplet-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS5 KIF21A RPS9 ITGA6 ITGB4 HMCN1

2.67e-051951336a31a8c0e8e666acfc6737fa2c54ebd6f35605520
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

WNT7B MRPS35 EPS8L1 KCNK1 ATXN10 GAREM1

2.74e-051961336547901c7a665770eff78eede69b8625b416c8186
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

WNT7B MRPS35 EPS8L1 KCNK1 ATXN10 GAREM1

2.74e-0519613366e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAM13C ITGA6 MPDZ ACVRL1 CDC42EP1 KDR

2.82e-051971336b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

IL16 CDH23 HMCN1 PLXDC2 SPON1 ROBO2

2.82e-051971336f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL16 CDH23 HMCN1 PLXDC2 SPON1 ROBO2

2.90e-0519813363ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA6 GRB10 MPDZ ACVRL1 CDC42EP1 KDR

2.90e-0519813362630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell367C|World / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQB2 KDM5D HMCN1 PLXDC2 C1QB ROBO2

2.90e-051981336ab3a178f392204e2d90eb5a3b5de7849986b1eaf
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA6 GRB10 MPDZ ACVRL1 CDC42EP1 KDR

2.90e-0519813361e83bec16dcd60460422625f89952ff506d6be51
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA6 ACVRL1 TENT5B HMCN1 KDR KIF17

2.99e-051991336d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA6 ACVRL1 TENT5B HMCN1 KDR KIF17

2.99e-051991336cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCell(02)_MMP9/10+|World / shred by cell type by condition

CUX2 ITGA6 SIK1 ITGB4 TENM2 ANKH

2.99e-0519913363f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NDOR1 WNT7B ARHGAP11A ITGB4 GREB1L PROM1

2.99e-051991336f0c289523957258d16135c04679db379d43d28d9
ToppCellmetastatic_Lymph_Node-Epithelial_cells-Malignant_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

WNT7B LAD1 CPD ITGB4 CDC42EP1 KCNK1

3.07e-0520013365e2def2e56f21bc7295cdcf3580f5c0d16a6a494
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_T_naive|Int-URO / Disease, condition lineage and cell class

PDK1 RPS5 SPTB ITGA6 ESPL1 LNX1

3.07e-052001336a4b531355e87efd6b69a16eeec8b1ff14c7af750
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRUNE2 DPYSL2 CDC42EP1 TP53TG5 SUN2 KCNK1

3.07e-0520013363ce8a2db8c25e1169a0a544f644a63104749c5ee
ToppCellTransverse-Dendritic_cell-cycling_DCs|Transverse / Region, Cell class and subclass

ACVRL1 ARHGAP11A PLXDC2 C1QB KIF18B ESPL1

3.07e-052001336f588d8889f351c797963616a3575fa43efd46b9a
ToppCellmetastatic_Lymph_Node-Epithelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

WNT7B LAD1 CPD ITGB4 CDC42EP1 KCNK1

3.07e-05200133607408011b37d32a20164866cf5da9dd120985357
ToppCellTransverse-(5)_Dendritic_cell-(52)_cycling_DCs|Transverse / shred on region, Cell_type, and subtype

ACVRL1 ARHGAP11A PLXDC2 C1QB KIF18B ESPL1

3.07e-05200133651e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCellParenchyma_Control_(B.)|World / Sample group, Lineage and Cell type

DPYSL2 DOCK11 PLXDC2 SUN2 C1QB GNAQ

3.07e-052001336220b6e5f936b3d08b031d6cabc5793213b98b8e2
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 MXRA5 HMCN1 PLXDC2 SPON1 ROBO2

3.07e-05200133658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DOCK11 GREB1L PROM1 SPON1

5.52e-05136133582b1d6d839c0d0c68e0960549f688138479defcc
ToppCellmetastatic_Brain-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

CDC42BPG OOEP DHX33 PLIN5 SPRYD3

7.99e-0514713354f7a0c287721befeffabf95b8c5f9ff64149c7c1
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SIK1 HROB PLXDC2 PCSK4 KIF17

9.64e-051531335e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DOCK11 GREB1L PROM1 SPON1

9.64e-051531335d6526d17826470534b766df144c74e73eb83fdad
ToppCellCV-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

PDK1 CDH23 ITGB4 CCDC7 SOCS1

9.94e-05154133526bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRB10 MPDZ OOEP SPON1 DHX35

1.06e-041561335895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM13C PIWIL2 TENM2 GREB1L GAREM1

1.12e-041581335f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM13C PIWIL2 TENM2 GREB1L GAREM1

1.12e-0415813358c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellPND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PRUNE2 XYLT2 C1QB DHX35 KIF18B

1.19e-0416013354480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

ITGB4 PLXDC2 CROCC PLXNB1 GAREM1

1.26e-041621335810881210e015c788814e4fe8d7a24c929cf2621
ToppCellfacs-Lung-Endomucin-24m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MON1A PTPN21 HS3ST6 CROCC PLXNB1

1.26e-041621335497ae9f86a5e7946d0fde932b35719a382a6b691
ToppCellfacs-Lung-Endomucin-24m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MON1A PTPN21 HS3ST6 CROCC PLXNB1

1.26e-0416213357b2949eba2b4aea239d96ed82aafab13b07624eb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP11A ATAD2 HROB KIF18B ESPL1

1.30e-0416313353f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WNT7B KCNK1 HS3ST6 KDR GAREM1

1.34e-041641335b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WNT7B KCNK1 HS3ST6 KDR GAREM1

1.34e-041641335c5b2001280a43da855017361a3f6071a0e492848
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PROM1 KCNK1 HS3ST6 FRMPD2B PLXNB1

1.34e-0416413359e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP11A ATAD2 HROB KIF18B ESPL1

1.37e-041651335eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CDC42BPG ITGA6 YTHDC2 DHX33 DHX35

1.45e-0416713357e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQB2 HMCN1 C1QB KIF18B LNX1

1.49e-041681335d7d19c93d1c3dd994e18e28d5f36ae7773ff5d7f
DiseasePhakomatosis cesioflammea

GNA11 GNAQ

1.99e-0521322C3838883
Diseasejunctional epidermolysis bullosa with pyloric atresia (is_implicated_in)

ITGA6 ITGB4

1.99e-0521322DOID:0060733 (is_implicated_in)
DiseaseCongenital hemangioma

GNA11 GNAQ

1.99e-0521322C0235753
DiseasePort-wine stain with oculocutaneous melanosis

GNA11 GNAQ

1.99e-0521322C1274879
Diseaseserum VEGFR2 concentration measurement

KDR LNX1

5.94e-0531322EFO_0006795
DiseaseEpidermolysis bullosa with pyloric atresia

ITGA6 ITGB4

5.94e-0531322C1856934
DiseaseMalignant melanoma of iris

GNA11 GNAQ

1.97e-0451322C0346373
DiseaseMalignant melanoma of choroid

GNA11 GNAQ

1.97e-0451322C0346388
Diseaseneuroimaging measurement, brain volume measurement

DPYSL2 GRB10 ATP13A2 KANSL1 ATXN10 KIF18B LNX1

3.14e-042861327EFO_0004346, EFO_0006930
Diseasepancreas volume

WNT7B FRMPD2 FRMPD2B

3.25e-04301323EFO_0600045
Diseasejunctional epidermolysis bullosa (is_implicated_in)

ITGA6 ITGB4

4.11e-0471322DOID:3209 (is_implicated_in)
DiseaseT-cell immunoglobulin and mucin domain 1 measurement

PTGFRN CYFIP2

4.11e-0471322EFO_0010812
Diseaseobesity (implicated_via_orthology)

DHX33 EIF6 PLIN5 GNA11 GNAQ PLXNB1

4.26e-042151326DOID:9970 (implicated_via_orthology)
Diseasecolorectal adenocarcinoma (is_implicated_in)

IL16 KDR PCSK4

5.16e-04351323DOID:0050861 (is_implicated_in)
DiseaseUveal melanoma

GNA11 GNAQ

5.46e-0481322C0220633
Diseaseage-related hearing impairment

MTHFD1L HLA-DQB2 GRB10 CDH23 SIK1 ACVR1B HS3ST6

6.59e-043241327EFO_0005782
Diseasepancreatic hormone measurement

FRMPD2 FRMPD2B

8.73e-04101322EFO_0020621
Diseaseschizophrenia, type 2 diabetes mellitus

MYCBP2 HLA-DQB2 PTGFRN

9.47e-04431323MONDO_0005090, MONDO_0005148
Diseasefibromuscular dysplasia

FRMPD2 FRMPD2B LNX1

1.01e-03441323EFO_1000938
Diseasetrimethyllysine measurement

DPYSL2 GNAQ

1.06e-03111322EFO_0009134
Diseaseresponse to ondansetron, QT interval

MPDZ LNX1

1.06e-03111322EFO_0004682, EFO_0020997
Diseaseeye disease

WNT7B FRMPD2 FRMPD2B

1.08e-03451323EFO_0003966
DiseaseFEV/FEC ratio

HLA-DQB2 KIF1B MRPS35 CDH23 ACVR1B ATP13A2 CYFIP2 DDX5 TP53TG5 HMCN1 PLXDC2 KDR ATXN10 LNX1

1.23e-03122813214EFO_0004713
DiseaseRetinitis Pigmentosa

PRPF6 PROM1 IFT88 CROCC

1.25e-031041324C0035334
Diseaseautism

TAF1C KDM5D TENM2

1.31e-03481323EFO_0003758
DiseasePneumoconiosis

CDH23 HS3ST6

1.74e-03141322C0032273
DiseaseBagassosis

CDH23 HS3ST6

1.74e-03141322C0004681
Diseasecolorectal health

TEX9 DHX35 GNAQ HERC2 ESPL1

2.15e-032011325EFO_0008460
Diseaseanthranilic acid measurement

KIF1B LNX1

2.29e-03161322EFO_0010460
DiseaseBlood Coagulation Disorders

ACVRL1 GNAQ

2.29e-03161322C0005779
Diseaseoptic disc size measurement

WNT7B CDC42EP1 HS3ST6 ATXN10 ARHGAP21

2.34e-032051325EFO_0004832
Diseaseelectrocardiography

MYCBP2 HLA-DQB2 ITGA6 MRPS35 YTHDC2 PROM1 CYP26C1 GNAQ

2.71e-035301328EFO_0004327
DiseaseAstigmatism

MPDZ TENM2 HERC2 LNX1

2.74e-031291324HP_0000483
Diseasewhite matter integrity

HLA-DQB2 SMARCAL1 KANSL1 LNX1

2.81e-031301324EFO_0004641
Diseasediabetic retinopathy

HLA-DQB2 TENM2 PLXDC2 KCNK1

3.31e-031361324EFO_0003770
Diseaseneutrophil count

PRUNE2 CUX2 MYCBP2 HLA-DQB2 KIF1B CDH23 MON1A ACVR1B ACVRL1 PTGFRN TENT5B GTF3C1 STARD3 LNX1

3.63e-03138213214EFO_0004833
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

HLA-DQB2 WNT7B ITGA6 DHX35 ATXN10 GNAQ

3.66e-033281326EFO_0008377, EFO_0008378
DiseaseAutoimmune Hepatitis

HLA-DQB2 CDC42EP1

3.94e-03211322EFO_0005676
Diseasesexual dimorphism measurement

RPS9 R3HCC1 GRB10 CPD MON1A ATP13A2 EIF6 HROB METRN AP5B1 CROCC PHIP

4.10e-03110613212EFO_0021796

Protein segments in the cluster

PeptideGeneStartEntry
ERRNTRIVVPNENVI

CCDC7

886

Q96M83
PSFRRIIENVDVITR

ACTR8

561

Q9H981
QRNRETAPRTIFQRV

ATXN10

36

Q9UBB4
PLFVQRTVARTIVLQ

ACVR1B

196

P36896
PFLVQRTVARQVALV

ACVRL1

191

P37023
VIRVQEPRARRVQCN

ARIH2

236

O95376
VIPVTRSLRARNIVQ

ATAD2

126

Q6PL18
VIITQPRRISAVSVA

DHX30

486

Q7L2E3
RTIQVRQRGSITPRI

CUX2

626

O14529
RTPAARDSIVREVIQ

MTHFD1L

66

Q6UB35
RENEPSVTQLVRLRA

CDH23

571

Q9H251
LVNPRDRRVVIIESV

ACTR10

81

Q9NZ32
RPQTNATVARRLVAR

R3HCC1

406

Q9Y3T6
SRRVPRLRAVVESQA

IQCN

76

Q9H0B3
QQDVLRVRVPTTGII

GNAQ

176

P50148
QRRIRELQAPATVQS

CDC42BPG

1216

Q6DT37
KRREIAQTVGVTPQR

NOBOX

301

O60393
TVIRIRNRHNDVIPT

PDK1

141

Q15118
EVRVINLIGQTPISR

ASB8

176

Q9H765
PVRVVAPEAAQTRVR

OBSL1

1266

O75147
RQRRQVVEAAQAPIQ

LAD1

96

O00515
TTRERQRQTIVIPDT

HIPK2

866

Q9H2X6
SAPDITVRNVVNIAR

HDX

76

Q7Z353
VRRTAQGRLVVQAPA

IGDCC3

316

Q8IVU1
SVITVVAARVLRQTP

METRN

206

Q9UJH8
VVSRRNPEDVQEIIV

RPS6KC1

36

Q96S38
IDDNIPRRTTQRIVA

DPYSL2

546

Q16555
PVVELNRIQVKRSRS

HERC2

4416

O95714
RVSQPVQLRSGNRII

KIF1B

611

O60333
AVVQRITVHVTRRPV

KCNK1

151

O00180
TPRVQRLNELEAQTR

KDM5D

66

Q9BY66
QIRKIVDQIRPDRQT

DDX5

261

P17844
RPETINQVILRTVGV

DDX60L

1586

Q5H9U9
AELRTTLQRQVEPTV

HLA-DQB2

116

P05538
TLQRRVKRSVVVPTD

PCSK4

106

Q6UW60
CVVRVQGRQQRVPAV

PLXNA3

721

P51805
NLDVVQTPRIRVTVV

PLXNB1

1276

O43157
QTPRIRVTVVSRMLQ

PLXNB1

1281

O43157
RTPQRVAQGLVRVSI

FAT2

2046

Q9NYQ8
TDIPISNIRRVIAQR

DLAT

421

P10515
IRNIVEKTRLPVNVT

GAREM1

236

Q9H706
ILRQAREPRQAVIVT

IL16

1181

Q14005
QVTASTSQQPVRRRR

KANSL1

841

Q7Z3B3
VHLVVSRQVRQRSPD

LNX1

456

Q8TBB1
RVTVTEVLRETARPQ

HROB

116

Q8N3J3
GNRVLVTVFRQTVVP

ELP1

396

O95163
VVLRQVVVSRPGRDE

AP5B1

521

Q2VPB7
DSVTIFRSRPVINIQ

ITGA6

496

P23229
FAQVTLREPLRQAVR

CYFIP2

486

Q96F07
PRSEVLVQQTLQRIR

GREB1L

711

Q9C091
VSRGDQVARIPVIRR

ITGB4

1001

P16144
RRPVVQVVDERVLVF

KIF18B

26

Q86Y91
VAVVQFQTRLKEPRR

NDOR1

401

Q9UHB4
DEPRDITVLRNRQVT

HMCN1

3626

Q96RW7
LQTQTVTVNPIRRRS

PTPN21

311

Q16825
NSLPDTVQIRRVEER

EIF6

86

P56537
LVEITVFGRPRVQNR

OOEP

91

A6NGQ2
RSPLVLVAVARTRQS

MON1A

311

Q86VX9
QTTPVIQALRRTRIR

ATP13A2

731

Q9NQ11
TQEPRGLVRQSVELR

CROCC

131

Q5TZA2
EVPQAPRVQQRVQTR

ESPL1

1376

Q14674
RVLVRQREQVTTPEN

IFT88

176

Q13099
VIGRQRRTVQSTVPE

DOCK11

76

Q5JSL3
LRSRRSQINVHRVPV

FCRL1

96

Q96LA6
QVARLVLERRVPRST

FRMPD2B

36

Q6IN97
VARLVLERRVPRSTQ

FRMPD2

1026

Q68DX3
RVVGVTQPRRVAAVT

DHX35

101

Q9H5Z1
TQPRRVAAVTVAGRV

DHX35

106

Q9H5Z1
RVFIPVLQSVTARII

EI24

91

O14681
QQDVLRVRVPTTGII

GNA11

176

P29992
ARQERVEVLPQARAS

CDC42EP1

336

Q00587
VTQLVDRTRIVIVPS

CPD

1021

O75976
ISRQGIIAVTQPRRV

DHX33

116

Q9H6R0
IIAVTQPRRVAAISL

DHX33

121

Q9H6R0
QRISRPIVNLFVSRD

ANKH

251

Q9HCJ1
ATRTINVPLRRDQTI

C1QB

126

P02746
RPVIRVSGAENVRTI

CYP26C1

91

Q6V0L0
VLARQVPQAVVRTAN

GPR142

221

Q7Z601
RQRVQRSQPVHILAV

GRB10

106

Q13322
SRQEVVRSVLEPQAV

CENATAC

161

Q86UT8
TPRRIKRSVENQESV

AHCTF1

1871

Q8WYP5
QRRPSVRAVISTVER

EPS8L1

191

Q8TE68
LIVVVRNPVTRAISD

HS3ST6

176

Q96QI5
NQRERELRCQPVVTV

KIF17

16

Q9P2E2
GRVVRVPTATLVRVV

PTGFRN

21

Q9P2B2
PSVRNPRARVVVLRV

MRPS35

161

P82673
RVRKQVVNIPSFIVR

RPS9

136

P46781
RQAVDVSPLRRVNQA

RPS5

136

P46782
TPVRQSVRRINSLLE

ARHGAP11A

836

Q6P4F7
AVTESTPRRRTRIQV

SPON1

131

Q9HCB6
SITQVARVVIERIAR

SPON1

396

Q9HCB6
VDRRIPRIENVATSI

PRUNE2

2221

Q8WUY3
NVVSMRRIVNTVPIT

NKPD1

396

Q17RQ9
RRIVNTVPITVRLLQ

NKPD1

401

Q17RQ9
VRTIGQPTRLRSVAQ

PIWIL2

701

Q8TC59
VVAQAVRHLPQSVRI

PRPF6

361

O94906
RPRVVLDVTEQISRF

TAF1C

96

Q15572
DIPDRVQRQTTTVVA

PROM1

366

O43490
LRRPVLQRQTSITQT

RHBDF1

66

Q96CC6
IVVIAPGRINARTRA

SMARCAL1

661

Q9NZC9
VVHRIQQIPNVRRRT

PLXDC2

286

Q6UX71
PQVQTEVTLVARREE

RUFY4

391

Q6ZNE9
VDPARRITIAQIRQH

SIK1B

261

A0A0B4J2F2
VDPARRITIAQIRQH

SIK1

261

P57059
VESPRERRSIQTLVQ

TENM2

521

Q9NT68
SPRVQRQVTSLLRRV

MYCBP2

4051

O75592
REPRVATVTRILRQT

PSMB10

111

P40306
ETVRLQPRIDQRTAI

FAM13C

141

Q8NE31
RIVATVGRENLARIP

SOCS1

181

O15524
VVSPRDFVNVRRIER

STARD3

341

Q14849
VQPRQIVQVVRSTLE

TENT5B

81

Q96A09
RTENITEIAQQRRPR

SUPT20HL2

11

P0C7V6
TEQPVSKVIERNRLR

TP53TG5

26

Q9Y2B4
QHVPEVEVQVKRRRT

SNURF

16

Q9Y675
VVSRNQSFLRTPIQR

SAV1

66

Q9H4B6
VQVEVVRASRLRQPT

WNT7B

236

P56706
ILSPTARAVRNVRNV

SPRYD3

351

Q8NCJ5
AGVSVRRARRQVLPV

TTLL8

601

A6PVC2
VPVRDQARIQSRRIT

nan

46

Q96MF0
DEAINVLRQTPQRVR

MPDZ

1691

O75970
TRSNRVVVDPVVTEQ

PHIP

1506

Q8WWQ0
AVVRLSARIRPTAVT

SUN2

611

Q9UH99
QERRTVPILFASTVR

SLC27A4

71

Q6P1M0
DESSVRVAVRIRPQL

KIF21A

6

Q7Z4S6
SIQRPAQSRDVTTRI

SAP130

331

Q9H0E3
NRRVNAIEHVIIPRI

ATP6V1D

166

Q9Y5K8
QRLCRTVNVVPVIAR

SEPTIN12

181

Q8IYM1
FVVRPRDQIVAQGRT

ROBO2

316

Q9HCK4
SIIRQIETQERPRDV

SPTB

1921

P11277
TQPRRLAAIAVAERV

YTHDC2

246

Q9H6S0
VRQLTVLERVAPTIT

KDR

656

P35968
NVVQRVVALPLVRAT

PLIN5

21

Q00G26
PLVRSAIEQVRFRIS

GTF3C1

701

Q12789
RVPQSVQIRQRSVSQ

ARHGAP21

446

Q5T5U3
IRDRQEVRSRPVSTQ

TEX9

61

Q8N6V9
PVAKVVRAVTSRQRA

XYLT2

91

Q9H1B5
VVPRINSRILTAERD

UGGT1

691

Q9NYU2
TADRAIPESQIRQVI

GEMIN4

466

P57678
RVRVKVVTAPATIRN

MXRA5

2336

Q9NR99
VAPESRNRIRVRQDL

NACC1

326

Q96RE7