Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

LGMN CTNNAL1 MARK1 SYNE1 SPTAN1 MYO18A ADNP DYSF TTBK2 TTBK1 CCDC88A FEZ1 SYNE2 CTNNA3 CEP70 KIF3C DMD CCDC181 KIF1C NIN

9.58e-06109912120GO:0008092
GeneOntologyMolecularFunctionrecombination hotspot binding

PRDM7 PRDM9

3.64e-0521212GO:0010844
GeneOntologyMolecularFunctiontelomeric DNA binding

TERF2 TERF2IP BLM TP53BP1

9.90e-05401214GO:0042162
GeneOntologyMolecularFunctiontau protein binding

LGMN MARK1 TTBK2 TTBK1

1.72e-04461214GO:0048156
GeneOntologyMolecularFunctiontubulin binding

ADNP DYSF TTBK2 CCDC88A FEZ1 CEP70 KIF3C CCDC181 KIF1C NIN

2.81e-0442812110GO:0015631
GeneOntologyMolecularFunctiontau-protein kinase activity

MARK1 TTBK2 TTBK1

3.07e-04221213GO:0050321
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

3.60e-0451212GO:0140444
GeneOntologyBiologicalProcesscentrosome localization

RANBP2 SYNE1 CCDC141 AKAP9 SYNE2 PARD3 NIN

1.25e-09351227GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

RANBP2 SYNE1 CCDC141 AKAP9 SYNE2 PARD3 NIN

1.54e-09361227GO:0061842
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

DHX36 NES RELN SYNE1 MYO18A PRDM7 ADNP TERF2 TERF2IP CRACD TTBK2 PRDM9 TTBK1 CCDC88A AKAP9 FEZ1 SYT1 PRKCI KIF3C DMD EIF4G3 PARD3 ARAP1 NIN

1.30e-06136612224GO:0051130
GeneOntologyBiologicalProcessregulation of organelle organization

KNTC1 DHX36 NES TCHP SYNE1 SPTAN1 PRDM7 DYSF TERF2 TERF2IP CRACD TTBK2 PRDM9 CCDC88A LATS1 AKAP9 FEZ1 SYNE2 CEP70 SYT1 EIF4G3 ARAP1 KNL1

3.40e-06134212223GO:0033043
GeneOntologyBiologicalProcessregulation of meiosis I

PRDM9 EIF4G3 KNL1

1.65e-0591223GO:0060631
GeneOntologyBiologicalProcessnegative regulation of DNA recombination

TERF2 TERF2IP BLM LIG3 TP53BP1

1.83e-05551225GO:0045910
GeneOntologyBiologicalProcessregulation of DNA metabolic process

DHX36 TFIP11 USP37 PRDM7 TERF2 TTF1 TERF2IP BLM LIG3 PRDM9 TAF7 TOP2B TP53BP1

3.01e-0556412213GO:0051052
GeneOntologyBiologicalProcessregulation of DNA recombination

PRDM7 TERF2 TERF2IP BLM LIG3 PRDM9 TP53BP1

3.12e-051501227GO:0000018
GeneOntologyBiologicalProcessprotection from non-homologous end joining at telomere

TFIP11 TERF2 TERF2IP

3.22e-05111223GO:0031848
GeneOntologyBiologicalProcessnegative regulation of DNA metabolic process

TFIP11 TERF2 TTF1 TERF2IP BLM LIG3 TP53BP1

3.84e-051551227GO:0051053
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

DHX36 RELN TCHP MARK1 SYNE1 ADNP NEDD4 TTBK2 CCDC88A FEZ1 SYNE2 PRKCI KIF3C DMD ARAP1 NIN

3.93e-0584612216GO:0120035
GeneOntologyBiologicalProcessnegative regulation of organelle organization

KNTC1 TCHP SPTAN1 DYSF TERF2 TERF2IP CRACD TTBK2 FEZ1 ARAP1 KNL1

4.14e-0542112211GO:0010639
GeneOntologyBiologicalProcessregulation of cell projection organization

DHX36 RELN TCHP MARK1 SYNE1 ADNP NEDD4 TTBK2 CCDC88A FEZ1 SYNE2 PRKCI KIF3C DMD ARAP1 NIN

4.98e-0586312216GO:0031344
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

VRK1 MARK1 TTBK2 TTBK1 LATS1 AKAP9 PRKCI TNKS1BP1 DMD

8.94e-053071229GO:0018105
GeneOntologyBiologicalProcessregulation of DNA recombination at telomere

TERF2 TERF2IP

1.04e-0431222GO:0072695
GeneOntologyBiologicalProcessnegative regulation of DNA recombination at telomere

TERF2 TERF2IP

1.04e-0431222GO:0048239
GeneOntologyBiologicalProcesspeptidyl-serine modification

VRK1 MARK1 TTBK2 TTBK1 LATS1 AKAP9 PRKCI TNKS1BP1 DMD

1.19e-043191229GO:0018209
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

PRDM7 PRDM9 EIF4G3 KNL1

1.44e-04451224GO:0040020
GeneOntologyBiologicalProcesspositive regulation of organelle organization

DHX36 NES PRDM7 TERF2 TERF2IP CRACD TTBK2 PRDM9 CCDC88A AKAP9 SYT1 EIF4G3

1.55e-0457412212GO:0010638
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

DHX36 RELN ADNP TTBK2 CCDC88A FEZ1 PRKCI KIF3C DMD ARAP1 NIN

1.71e-0449412211GO:0031346
GeneOntologyBiologicalProcessprotein localization to chromosome

KNTC1 VRK1 TERF2 TERF2IP TP53BP1 KNL1

1.86e-041401226GO:0034502
GeneOntologyBiologicalProcesspositive regulation of reciprocal meiotic recombination

PRDM7 PRDM9

2.07e-0441222GO:0010845
GeneOntologyBiologicalProcessregulation of reciprocal meiotic recombination

PRDM7 PRDM9

2.07e-0441222GO:0010520
GeneOntologyBiologicalProcessDNA metabolic process

DHX36 POLE MYO18A TFIP11 USP37 PRDM7 TERF2 TTF1 TERF2IP BLM LIG3 PRDM9 TNKS1BP1 TAF7 ASF1A TOP2B TP53BP1

2.12e-04108112217GO:0006259
GeneOntologyBiologicalProcessprotein localization to organelle

TNPO1 KNTC1 NUP50 RANBP2 VRK1 SYNE1 RANBP6 TERF2 TERF2IP NEDD4 TTBK2 CCDC88A LATS1 ARIH2 SEC63 TP53BP1 KNL1

2.36e-04109112217GO:0033365
GeneOntologyBiologicalProcessorganelle localization

KNTC1 MARK1 SYNE1 NCAM1 SDAD1 AKAP9 FEZ1 SYNE2 SYT1 DMD PARD3 KNL1 KIF1C

2.72e-0470312213GO:0051640
GeneOntologyBiologicalProcessregulation of neuron projection development

DHX36 RELN MARK1 SYNE1 ADNP NEDD4 CCDC88A FEZ1 PRKCI KIF3C DMD NIN

2.78e-0461212212GO:0010975
GeneOntologyBiologicalProcesstelomeric loop formation

TERF2 TERF2IP

3.43e-0451222GO:0031627
GeneOntologyBiologicalProcesspositive regulation of meiosis I

PRDM9 EIF4G3

3.43e-0451222GO:0060903
GeneOntologyBiologicalProcessnegative regulation of mitotic recombination

TERF2 BLM

3.43e-0451222GO:0045950
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GABRG1 LGMN RELN SYNE1 NCAM1 ADNP DYSF ZZEF1 SYAP1 NEDD4 AKAP9 OTOF SYT1 DMD MCTP2

3.98e-0493112215GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GABRG1 LGMN RELN SYNE1 NCAM1 ADNP DYSF ZZEF1 SYAP1 NEDD4 AKAP9 OTOF SYT1 DMD MCTP2

3.98e-0493112215GO:0007268
GeneOntologyBiologicalProcessregulation of protein depolymerization

NES SPTAN1 DYSF CRACD TTBK2

4.02e-041051225GO:1901879
GeneOntologyBiologicalProcessnegative regulation of protein binding

NES TFIP11 DYSF TTBK2 TTBK1

4.20e-041061225GO:0032091
GeneOntologyBiologicalProcesstrans-synaptic signaling

GABRG1 LGMN RELN SYNE1 NCAM1 ADNP DYSF ZZEF1 SYAP1 NEDD4 AKAP9 OTOF SYT1 DMD MCTP2

4.35e-0493912215GO:0099537
GeneOntologyBiologicalProcessregulation of cilium assembly

TCHP SYNE1 TTBK2 CCDC88A SYNE2

4.57e-041081225GO:1902017
GeneOntologyBiologicalProcessDNA repair

POLE TFIP11 TERF2 TERF2IP BLM LIG3 PRDM9 TNKS1BP1 TAF7 ASF1A TOP2B TP53BP1

4.65e-0464812212GO:0006281
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

PRDM7 PRDM9 EIF4G3

4.75e-04261223GO:0045836
GeneOntologyBiologicalProcessregulation of DNA repair

TFIP11 TERF2 TERF2IP BLM TAF7 TOP2B TP53BP1

4.90e-042341227GO:0006282
GeneOntologyBiologicalProcesstelomere maintenance

DHX36 TFIP11 TERF2 TERF2IP BLM TNKS1BP1

4.95e-041681226GO:0000723
GeneOntologyBiologicalProcessmicrotubule-based process

MARK1 APOB DYSF TERF2 TTBK2 CCDC88A AKAP9 FEZ1 SYNE2 CEP70 KIF3C CCDC102B PARD3 CFAP46 KIF1C NIN

5.06e-04105812216GO:0007017
GeneOntologyBiologicalProcessDNA damage response

VRK1 POLE TFIP11 TERF2 TERF2IP NEDD4 BLM LIG3 PRDM9 STK33 TNKS1BP1 TAF7 ASF1A TOP2B TP53BP1

5.42e-0495912215GO:0006974
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

LGMN RELN SYNE1 NCAM1 ADNP DYSF ZZEF1 SYAP1 NEDD4 OTOF SYT1 MCTP2

5.70e-0466312212GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

LGMN RELN SYNE1 NCAM1 ADNP DYSF ZZEF1 SYAP1 NEDD4 OTOF SYT1 MCTP2

5.77e-0466412212GO:0099177
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

TCHP MARK1 SYNE1 SPTAN1 NCAM1 TFIP11 ADNP TERF2 CRACD TTBK2 TTBK1 CCDC88A LATS1 AKAP9 FEZ1 SYNE2 ARAP1

6.33e-04118912217GO:0044087
GeneOntologyBiologicalProcesssynaptic signaling

GABRG1 LGMN RELN SYNE1 NCAM1 ADNP DYSF ZZEF1 SYAP1 NEDD4 AKAP9 OTOF SYT1 DMD MCTP2

6.49e-0497612215GO:0099536
GeneOntologyBiologicalProcessforebrain development

RELN DUOX2 NCAM1 CCDC141 TTBK2 FEZ1 SYNE2 EIF2B5 TOP2B NIN

6.60e-0448912210GO:0030900
GeneOntologyBiologicalProcessdouble-strand break repair

TFIP11 TERF2IP BLM LIG3 PRDM9 TNKS1BP1 TOP2B TP53BP1

6.95e-043241228GO:0006302
GeneOntologyBiologicalProcesspositive regulation of neuron projection development

DHX36 RELN ADNP FEZ1 PRKCI KIF3C DMD

7.09e-042491227GO:0010976
GeneOntologyBiologicalProcessG-quadruplex DNA unwinding

DHX36 BLM

7.15e-0471222GO:0044806
GeneOntologyBiologicalProcesschromosome organization

KNTC1 DHX36 TFIP11 ERN2 TERF2 TERF2IP BLM PRDM9 LATS1 TNKS1BP1 TOP2B KNL1

7.68e-0468612212GO:0051276
GeneOntologyBiologicalProcessprotein K48-linked deubiquitination

OTUD5 USP25 USP37

8.04e-04311223GO:0071108
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

DHX36 PRDM7 TERF2 TERF2IP BLM PRDM9 TOP2B TP53BP1

8.30e-043331228GO:0051054
GeneOntologyBiologicalProcessregulation of phosphorylation

RANBP2 RELN ADNP ERN2 ZZEF1 SYAP1 TERF2IP BLM TTBK1 CCDC88A LATS1 AKAP9 TNKS1BP1 DMD TAF7 EIF4G3 PARD3

8.89e-04122612217GO:0042325
GeneOntologyBiologicalProcessregulation of mitotic recombination

TERF2 BLM

9.49e-0481222GO:0000019
GeneOntologyBiologicalProcessregulation of protein phosphorylation

RELN ADNP ERN2 ZZEF1 SYAP1 TERF2IP BLM TTBK1 CCDC88A LATS1 AKAP9 TNKS1BP1 DMD TAF7 EIF4G3 PARD3

1.05e-03113312216GO:0001932
GeneOntologyCellularComponentchromosomal region

KNTC1 DHX36 KDM4C ZNF618 TFIP11 TERF2 TERF2IP BLM TP53BP1 KNL1

1.96e-0442112310GO:0098687
GeneOntologyCellularComponentsomatodendritic compartment

GABRG1 DHX36 RELN MARK1 SYNE1 NCAM1 APOB ADNP SYAP1 NEDD4 TTBK1 AKAP9 FEZ1 KIF3C DMD PARD3 KIF1C NIN

3.03e-04122812318GO:0036477
GeneOntologyCellularComponentPAR polarity complex

PRKCI PARD3

5.07e-0461232GO:0120157
GeneOntologyCellularComponentchromosome, telomeric region

DHX36 TFIP11 TERF2 TERF2IP BLM TP53BP1

6.16e-041761236GO:0000781
GeneOntologyCellularComponentexocytic vesicle membrane

DYSF OTOF CLTB SYT1 DMD MCTP2

6.73e-041791236GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

DYSF OTOF CLTB SYT1 DMD MCTP2

6.73e-041791236GO:0030672
GeneOntologyCellularComponentshelterin complex

TERF2 TERF2IP

7.07e-0471232GO:0070187
GeneOntologyCellularComponentaxon

DHX36 RELN SPTAN1 NCAM1 ADNP TERF2 SYAP1 FEZ1 SYT1 KIF3C DMD PARD3 KIF1C NIN

7.63e-0489112314GO:0030424
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle membrane

OTOF SYT1

1.20e-0391232GO:0060203
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle

OTOF SYT1

1.20e-0391232GO:0060199
GeneOntologyCellularComponentciliary transition fiber

TCHP NIN

1.50e-03101232GO:0097539
GeneOntologyCellularComponentdendrite

GABRG1 DHX36 RELN MARK1 SYNE1 ADNP SYAP1 NEDD4 AKAP9 FEZ1 KIF3C KIF1C NIN

1.64e-0385812313GO:0030425
GeneOntologyCellularComponentmale germ cell nucleus

TERF2 TERF2IP BLM TAF7

1.67e-03861234GO:0001673
GeneOntologyCellularComponentdendritic tree

GABRG1 DHX36 RELN MARK1 SYNE1 ADNP SYAP1 NEDD4 AKAP9 FEZ1 KIF3C KIF1C NIN

1.67e-0386012313GO:0097447
GeneOntologyCellularComponentclathrin-coated vesicle membrane

APOB IGF2R OTOF CLTB SYT1

1.78e-031471235GO:0030665
GeneOntologyCellularComponentpostsynaptic endocytic zone

SH3GLB2 CLTB

1.82e-03111232GO:0098843
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

1.82e-03111232GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.82e-03111232GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

1.82e-03111232GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.82e-03111232GO:0034993
GeneOntologyCellularComponentsynaptic vesicle

DYSF OTOF CLTB SYT1 KIF3C DMD MCTP2

2.01e-033001237GO:0008021
GeneOntologyCellularComponentnuclear telomere cap complex

TERF2 TERF2IP

2.57e-03131232GO:0000783
GeneOntologyCellularComponenttelomere cap complex

TERF2 TERF2IP

2.57e-03131232GO:0000782
GeneOntologyCellularComponentfascia adherens

SPTAN1 CTNNA3

2.57e-03131232GO:0005916
GeneOntologyCellularComponentexocytic vesicle

DYSF OTOF CLTB SYT1 KIF3C DMD MCTP2

2.89e-033201237GO:0070382
GeneOntologyCellularComponentchromosome, telomeric repeat region

TERF2 TERF2IP

2.98e-03141232GO:0140445
GeneOntologyCellularComponentheterochromatin

KDM4C ZNF618 TNKS1BP1 TOP2B

3.00e-031011234GO:0000792
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

APOB IGF2R CLTB SYT1

3.00e-031011234GO:0045334
GeneOntologyCellularComponentgrowth cone

NCAM1 SYAP1 FEZ1 KIF3C PARD3 NIN

3.31e-032451236GO:0030426
GeneOntologyCellularComponenttransport vesicle

DYSF CCDC88A IGF2R OTOF CLTB SYT1 KIF3C DMD MCTP2

3.61e-035191239GO:0030133
GeneOntologyCellularComponentneuronal cell body

DHX36 RELN NCAM1 APOB ADNP SYAP1 TTBK1 AKAP9 FEZ1 KIF3C DMD PARD3

3.80e-0383512312GO:0043025
GeneOntologyCellularComponentsite of polarized growth

NCAM1 SYAP1 FEZ1 KIF3C PARD3 NIN

3.88e-032531236GO:0030427
GeneOntologyCellularComponentclathrin-sculpted vesicle

OTOF SYT1

3.90e-03161232GO:0060198
GeneOntologyCellularComponentsupramolecular fiber

KNTC1 NES TCHP SYNE1 SPTAN1 MYO18A DYSF RYR3 FEZ1 SYNE2 KIF3C DMD CCDC181 KIF1C NIN

3.92e-03117912315GO:0099512
DomaineIF5C

BZW2 EIF2B5 BZW1 EIF4G3

5.22e-0871184SM00515
DomainW2

BZW2 EIF2B5 BZW1 EIF4G3

5.22e-0871184PF02020
DomainW2

BZW2 EIF2B5 BZW1 EIF4G3

5.22e-0871184PS51363
DomainW2_domain

BZW2 EIF2B5 BZW1 EIF4G3

5.22e-0871184IPR003307
DomainSpectrin

SYNE1 SPTAN1 CCDC141 SYNE2 DMD

2.84e-07231185PF00435
DomainSpectrin_repeat

SYNE1 SPTAN1 CCDC141 SYNE2 DMD

9.72e-07291185IPR002017
Domain-

BZW2 EIF2B5 BZW1 EIF4G3

1.96e-061511841.25.40.180
DomainMIF4-like

BZW2 EIF2B5 BZW1 EIF4G3

1.96e-06151184IPR016021
DomainSANT/Myb

DMTF1 TERF2 TTF1 TERF2IP ZSCAN20

1.90e-05521185IPR001005
DomainSPEC

SYNE1 SPTAN1 SYNE2 DMD

4.75e-05321184SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTAN1 SYNE2 DMD

4.75e-05321184IPR018159
DomainMYB_LIKE

DMTF1 TERF2 TTF1 TERF2IP

9.47e-05381184PS50090
DomainKASH

SYNE1 SYNE2

2.36e-0441182IPR012315
DomainKASH

SYNE1 SYNE2

2.36e-0441182PS51049
DomainAlpha_catenin

CTNNAL1 CTNNA3

2.36e-0441182IPR001033
DomainKASH

SYNE1 SYNE2

2.36e-0441182SM01249
DomainKASH

SYNE1 SYNE2

2.36e-0441182PF10541
DomainSANT

DMTF1 TERF2 TTF1 ZSCAN20

2.79e-04501184SM00717
DomainARM-type_fold

TNPO1 BZW2 RANBP6 APOB SDAD1 RYR3 EIF2B5 BZW1 EIF4G3

3.03e-043391189IPR016024
Domain-

DYSF NEDD4 OTOF SYT1 SEC63 MCTP2

3.56e-0414811862.60.40.150
DomainFerI

DYSF OTOF

3.91e-0451182SM01202
DomainFerB

DYSF OTOF

3.91e-0451182SM01201
DomainFerlin_B-domain

DYSF OTOF

3.91e-0451182IPR012561
DomainFerlin_C

DYSF OTOF

3.91e-0451182PF16165
DomainFerlin_C

DYSF OTOF

3.91e-0451182IPR032362
DomainFerIin_dom

DYSF OTOF

3.91e-0451182IPR012968
DomainFerI

DYSF OTOF

3.91e-0451182PF08151
DomainFerB

DYSF OTOF

3.91e-0451182PF08150
DomainVinculin

CTNNAL1 CTNNA3

3.91e-0451182PF01044
DomainACTININ_2

SYNE1 SYNE2 DMD

3.97e-04231183PS00020
DomainACTININ_1

SYNE1 SYNE2 DMD

3.97e-04231183PS00019
DomainActinin_actin-bd_CS

SYNE1 SYNE2 DMD

3.97e-04231183IPR001589
DomainSCAN

ZSCAN32 ZSCAN20 ZSCAN2 ZNF287

4.32e-04561184SM00431
DomainSCAN_BOX

ZSCAN32 ZSCAN20 ZSCAN2 ZNF287

4.94e-04581184PS50804
DomainSCAN

ZSCAN32 ZSCAN20 ZSCAN2 ZNF287

4.94e-04581184PF02023
DomainSCAN_dom

ZSCAN32 ZSCAN20 ZSCAN2 ZNF287

4.94e-04581184IPR003309
DomainRetrov_capsid_C

ZSCAN32 ZSCAN20 ZSCAN2 ZNF287

5.27e-04591184IPR008916
DomainBRCT

TERF2IP LIG3 TP53BP1

5.75e-04261183PS50172
DomainMyb-like_dom

DMTF1 TTF1

5.84e-0461182IPR017877
DomainC2_dom

DYSF NEDD4 OTOF SYT1 SEC63 MCTP2

6.13e-041641186IPR000008
DomainBRCT_dom

TERF2IP LIG3 TP53BP1

7.18e-04281183IPR001357
DomainVinculin/catenin

CTNNAL1 CTNNA3

8.14e-0471182IPR006077
DomainSSXRD

PRDM7 PRDM9

1.08e-0381182PF09514
DomainSSXRD_motif

PRDM7 PRDM9

1.08e-0381182IPR019041
DomainHTH_MYB

DMTF1 TERF2

1.38e-0391182PS51294
DomainMyb_dom

DMTF1 TERF2

1.38e-0391182IPR017930
DomainMyb_DNA-binding

DMTF1 TERF2 TTF1

1.39e-03351183PF00249
DomainDNA/RNA_helicase_DEAH_CS

DHX16 DHX36 BLM

1.39e-03351183IPR002464
DomainC2

DYSF NEDD4 OTOF SYT1 MCTP2

1.46e-031311185PF00168
DomainDEAH_ATP_HELICASE

DHX16 DHX36 BLM

1.77e-03381183PS00690
DomainC2

DYSF NEDD4 OTOF SYT1 MCTP2

1.78e-031371185SM00239
DomainS_TKc

VRK1 MARK1 ERN2 TTBK2 TTBK1 LATS1 STK33 PRKCI

2.02e-033591188SM00220
DomainC2

DYSF NEDD4 OTOF SYT1 MCTP2

2.08e-031421185PS50004
DomainKRAB_RELATED

PRDM7 PRDM9

2.10e-03111182PS50806
DomainPROTEIN_KINASE_ST

VRK1 MARK1 ERN2 TTBK2 TTBK1 LATS1 STK33 PRKCI

2.12e-033621188PS00108
Domain-

DMTF1 POGK ADNP TERF2 TTF1 TERF2IP JRKL

2.15e-0328311871.10.10.60
DomainRan_BP1

NUP50 RANBP2

2.51e-03121182PF00638
DomainRANBD1

NUP50 RANBP2

2.51e-03121182PS50196
DomainCENPB

POGK JRKL

2.51e-03121182SM00674
DomainDDE_1

POGK JRKL

2.51e-03121182PF03184
DomainDDE_SF_endonuclease_dom

POGK JRKL

2.51e-03121182IPR004875
DomainPkinase

VRK1 MARK1 ERN2 TTBK2 TTBK1 LATS1 STK33 PRKCI

2.91e-033811188PF00069
DomainHTH_CENPB

POGK JRKL

2.95e-03131182PS51253
DomainHTH_Tnp_Tc5

POGK JRKL

2.95e-03131182PF03221
DomainRanBD

NUP50 RANBP2

2.95e-03131182SM00160
DomainKrueppel-associated_box-rel

PRDM7 PRDM9

2.95e-03131182IPR003655
DomainRan_bind_dom

NUP50 RANBP2

2.95e-03131182IPR000156
DomainHTH_CenpB_DNA-bd_dom

POGK JRKL

2.95e-03131182IPR006600
DomainWW

NEDD4 WBP4 DMD

3.26e-03471183PF00397
DomainWW

NEDD4 WBP4 DMD

3.46e-03481183SM00456
DomainWW_DOMAIN_1

NEDD4 WBP4 DMD

4.11e-03511183PS01159
DomainWW_DOMAIN_2

NEDD4 WBP4 DMD

4.11e-03511183PS50020
DomainWW_dom

NEDD4 WBP4 DMD

4.34e-03521183IPR001202
DomainQuinoprotein_ADH-like_supfam

NWD1 ERN2 WDR87

4.58e-03531183IPR011047
DomainDUF1605

DHX16 DHX36

5.06e-03171182IPR011709
DomainOB_NTP_bind

DHX16 DHX36

5.06e-03171182PF07717
DomainHomeodomain-like

DMTF1 POGK ADNP TERF2 TTF1 TERF2IP JRKL

5.16e-033321187IPR009057
DomainUIM

USP25 USP37

5.67e-03181182PF02809
DomainZF_ZZ_2

ZZEF1 DMD

5.67e-03181182PS50135
DomainZF_ZZ_1

ZZEF1 DMD

5.67e-03181182PS01357
DomainZZ

ZZEF1 DMD

5.67e-03181182PF00569
DomainHA2

DHX16 DHX36

5.67e-03181182SM00847
DomainHA2

DHX16 DHX36

5.67e-03181182PF04408
DomainHelicase-assoc_dom

DHX16 DHX36

5.67e-03181182IPR007502
DomainHEAT

TNPO1 RANBP6 EIF4G3

5.89e-03581183IPR000357
Domain-

SPTAN1 DUOX2 ZZEF1 RYR3 DMD NIN

6.30e-0326111861.10.238.10
DomainZnf_ZZ

ZZEF1 DMD

6.31e-03191182IPR000433
DomainZnF_ZZ

ZZEF1 DMD

6.31e-03191182SM00291
PathwayREACTOME_CELL_CYCLE

TNPO1 KNTC1 NUP50 RANBP2 VRK1 SYNE1 POLE MDM4 TERF2 TERF2IP BLM PRDM9 AKAP9 SYNE2 CEP70 TP53BP1 KNL1

7.91e-076948617M543
PathwayREACTOME_MEIOSIS

SYNE1 TERF2 TERF2IP BLM PRDM9 SYNE2

9.06e-05120866M529
PathwayREACTOME_PROCESSIVE_SYNTHESIS_ON_THE_C_STRAND_OF_THE_TELOMERE

TERF2 TERF2IP BLM

1.67e-0418863MM14682
PathwayREACTOME_PROCESSIVE_SYNTHESIS_ON_THE_C_STRAND_OF_THE_TELOMERE

TERF2 TERF2IP BLM

1.98e-0419863M27029
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DHX16 TNPO1 KNTC1 DHX36 NUP50 RANBP2 VRK1 SYNE1 POLE SPTAN1 DUOX2 APOB PRDM7 ADNP SUCLA2 SYAP1 TBL3 SDAD1 UBE4A LIG3 IGF2R EIF2B5 PRKCI KIF3C BZW1 SEC63 ASF1A TOP2B

1.22e-1314251242830948266
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNPO1 PDE3B TCHP SYNE1 POLE COQ5 SPTAN1 MYO18A TFIP11 SUCLA2 TBL3 DMXL1 BLM FAM204A UBE4A CCDC88A IGF2R AKAP9 SYNE2 PRKCI CRYBG3 SEC63 EIF4G3 PARD3 TOP2B TP53BP1 NIN

2.27e-1214871242733957083
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DHX16 TNPO1 DHX36 NES RANBP2 RELN VRK1 MARK1 ZNF618 SYNE1 SPTAN1 HECTD4 MYO18A TFIP11 ADNP SDAD1 BLM LIG3 SNRNP48 TNKS1BP1 SEC63 TOP2B

3.88e-1110821242238697112
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX16 TNPO1 DHX36 NES RANBP2 POLE SPTAN1 ADNP TTF1 TBL3 BLM IGF2R SYNE2 TNKS1BP1 EIF4G3 TP53BP1

1.66e-096531241622586326
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DHX16 RANBP2 OTUD5 SPTAN1 MYO18A TFIP11 TERF2 SYAP1 TERF2IP BLM LATS1 EIF2B5 TNKS1BP1 PARD3 TOP2B TP53BP1

1.81e-087741241615302935
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NUP50 RANBP2 CTNNAL1 BZW2 SPTAN1 TERF2 SDAD1 BLM CCDC88A IGF2R AKAP9 SYNE2 CLTB PRKCI CRYBG3 DMD KNL1 NIN

3.74e-0810491241827880917
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

TNPO1 RANBP2 CTNNAL1 BZW2 SYAP1 CCDC88A LATS1 IGF2R TNKS1BP1 BZW1 CRYBG3 SEC63 TAF7 EIF4G3 PARD3

3.79e-087081241539231216
Pubmed

Dysferlin deficiency enhances monocyte phagocytosis: a model for the inflammatory onset of limb-girdle muscular dystrophy 2B.

DYSF IGF2R DMD

4.42e-083124318276788
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES RANBP2 ZNF618 SYNE1 SPTAN1 HECTD4 NCAM1 ADNP NEDD4 CCDC88A IGF2R AKAP9 SYNE2 SYT1 PRKCI PARD3 TP53BP1

6.19e-089631241728671696
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

SYNE1 SPTAN1 TFIP11 CCDC88A AKAP9 ARIH2 KIF3C DMD

7.54e-08151124817043677
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

NUP50 RANBP2 POLE CCDC141 TERF2 TERF2IP LIG3 WBP4 TNKS1BP1 TAF7 TOP2B TP53BP1

1.28e-074691241227634302
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

NES RELN SYNE1 SYNE2

1.50e-0714124419874786
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RELN KDM4C SYNE1 SPTAN1 HECTD4 USP25 SH3GLB2 TFIP11 TERF2IP TRIM52 RYR3 UBE4A SNRNP48 OTOF FEZ1 ARIH2 CEP70 MIGA1 EIF4G3

1.54e-0712851241935914814
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DHX16 KNTC1 NUP50 RANBP2 POGK SYNE1 TFIP11 TERF2 BLM TTBK2 RBAK PRKCI TNKS1BP1 TOP2B TP53BP1 ARAP1 KNL1 KIF1C

1.57e-0711551241820360068
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

SYNE1 SPTAN1 TFIP11 CCDC88A AKAP9 KIF3C DMD

2.63e-07120124731413325
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NUP50 RANBP2 POGK TERF2 SYAP1 TERF2IP BLM TNKS1BP1 BZW1 EIF4G3 TP53BP1 KIF1C

2.71e-075031241216964243
Pubmed

Lgl1 deficiency disrupts hippocampal development and impairs cognitive performance in mice.

NES RELN PRKCI PARD3

2.71e-0716124431415124
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NES PDE3B SPTAN1 MDM4 NEDD4 CCDC88A LATS1 AKAP9 SYNE2 PRKCI TNKS1BP1 CRYBG3 EIF4G3 PARD3 KIF1C

4.65e-078611241536931259
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DHX16 DHX36 PDE3B SAMD9 POGK POLE TFIP11 ZZEF1 LIG3 CCDC88A EIF2B5 PRKCI CRYBG3

6.20e-076501241338777146
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KNTC1 TCHP MARK1 SPTAN1 SH3GLB2 LATS1 AKAP9 PRKCI PARD3 KIF1C NIN

6.29e-074461241124255178
Pubmed

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

NES NCAM1 CCDC88A

8.78e-076124319778507
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

KNTC1 TCHP OTUD5 SH3GLB2 MDM4 BLM CCDC88A TNKS1BP1 CRYBG3 TP53BP1 KNL1 NIN

1.39e-065881241238580884
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

DHX36 PDE3B SYNE1 POLE COQ5 SH3GLB2 RANBP6 SUCLA2 ZZEF1 SYAP1 TBL3 BLM UBE4A AKAP9 SYNE2 MIGA1 PRKCI CRYBG3 SEC63

1.51e-0614961241932877691
Pubmed

TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.

TERF2IP BLM TP53BP1

1.53e-067124325344324
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TNPO1 DMTF1 LGMN CTNNAL1 MARK1 TFIP11 APOB DEPDC1 TTBK2 AMMECR1L IGF2R TCP11L2 SYT1 SEC63 PARD3 TP53BP1

1.65e-0610841241611544199
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

DHX16 RANBP2 VRK1 POLE DEPDC1 MDM4 ADNP TTF1 BLM UBE4A CRACD LIG3 TOP2B TP53BP1

2.43e-068571241425609649
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

NUP50 BZW2 MARK1 MYO18A USP25 SUCLA2 TBL3 SNRNP48 LATS1 IGF2R AKAP9 BZW1 NIN

3.18e-067541241333060197
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

DHX36 POLE MYO18A TERF2 TTF1 TBL3 SDAD1 TERF2IP BLM LIG3 EIF2B5 EIF4G3 TOP2B

3.42e-067591241335915203
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

DHX36 TCHP POLE SH3GLB2 CCDC88A SYNE2 KIF1C NIN

3.52e-06251124829778605
Pubmed

Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice.

NES RELN NCAM1

3.66e-069124316571605
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

TNPO1 KNTC1 RANBP2 BZW2 SPTAN1 RANBP6 SUCLA2 SDAD1 UBE4A CRACD LIG3 SYNE2 CLTB EIF2B5 TNKS1BP1 BZW1 SEC63 TOP2B

3.67e-0614401241830833792
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

DHX36 TFIP11 ADNP LIG3 EIF2B5 TNKS1BP1 TAF7 TOP2B TP53BP1

3.98e-06341124932971831
Pubmed

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.

MARK1 MYO18A CCDC88A PRKCI PARD3

4.63e-0668124514676191
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

ZNF618 SYNE1 SPTAN1 MYO18A ZZEF1 SYNE2 DMD

5.14e-06187124726460568
Pubmed

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.

NES PRKCI PARD3

5.21e-0610124332150534
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

NUP50 RANBP2 TTF1 CCDC88A SYNE2 EIF4G3

5.50e-06123124626912792
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

DHX16 NES RELN SPTAN1 ADNP LIG3 CLTB TNKS1BP1 TP53BP1

6.16e-06360124933111431
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

SYNE1 TERF2 SYNE2

7.15e-0611124322826121
Pubmed

The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse.

NES RELN NCAM1

9.51e-0612124312727448
Pubmed

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.

PRKCI PARD3 NIN

9.51e-0612124322031545
Pubmed

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.

CTNNAL1 FEZ1 TP53BP1

1.23e-0513124314690447
Pubmed

Retinoic acid from the meninges regulates cortical neuron generation.

NES PRKCI PARD3

1.23e-0513124319879845
Pubmed

Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import.

TNPO1 RANBP2

1.26e-052124232161167
Pubmed

Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injury.

DYSF DMD

1.26e-052124217607357
Pubmed

A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends.

TERF2 TERF2IP

1.26e-052124217499040
Pubmed

Human Rap1 modulates TRF2 attraction to telomeric DNA.

TERF2 TERF2IP

1.26e-052124225675958
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

1.26e-052124211792814
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

1.26e-052124224931616
Pubmed

Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.

OTOF SYT1

1.26e-052124221451027
Pubmed

Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation.

BZW2 BZW1

1.26e-052124236333315
Pubmed

Ginsenoside Rg3 regulates DNA damage in non-small cell lung cancer cells by activating VRK1/P53BP1 pathway.

VRK1 TP53BP1

1.26e-052124231629252
Pubmed

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.

TTBK2 TTBK1

1.26e-052124237059819
Pubmed

Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy.

DYSF DMD

1.26e-052124227834955
Pubmed

TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends.

TERF2 TERF2IP

1.26e-052124220407424
Pubmed

Rap1 affects the length and heterogeneity of human telomeres.

TERF2 TERF2IP

1.26e-052124214565979
Pubmed

Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCι in complex with a substrate peptide from Par-3.

PRKCI PARD3

1.26e-052124222579248
Pubmed

Attenuated muscle regeneration is a key factor in dysferlin-deficient muscular dystrophy.

DYSF DMD

1.26e-052124219286669
Pubmed

Human Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomere.

TERF2 TERF2IP

1.26e-052124223086976
Pubmed

Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy.

DYSF DMD

1.26e-052124226206886
Pubmed

A higher-order entity formed by the flexible assembly of RAP1 with TRF2.

TERF2 TERF2IP

1.26e-052124226748096
Pubmed

Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo.

PRKCI PARD3

1.26e-052124215657073
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

1.26e-052124222768332
Pubmed

Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle.

DYSF DMD

1.26e-052124237599828
Pubmed

Human telomeric proteins occupy selective interstitial sites.

TERF2 TERF2IP

1.26e-052124221423278
Pubmed

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.

TTBK2 TTBK1

1.26e-052124229409526
Pubmed

Expression of NCAM and its polysialylated isoforms during mdx mouse muscle regeneration and in vitro myogenesis.

NCAM1 DMD

1.26e-05212427919966
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

1.26e-052124217267447
Pubmed

Basic domain of telomere guardian TRF2 reduces D-loop unwinding whereas Rap1 restores it.

TERF2 TERF2IP

1.26e-052124228981702
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

1.26e-052124224718612
Pubmed

Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null mice.

DYSF DMD

1.26e-052124222132688
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

1.26e-052124224586179
Pubmed

Altered mRNA expression of telomere binding proteins (TPP1, POT1, RAP1, TRF1 and TRF2) in ulcerative colitis and Crohn's disease.

TERF2 TERF2IP

1.26e-052124220061197
Pubmed

Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms.

TTBK2 TTBK1

1.26e-052124232424773
Pubmed

Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection.

BZW2 BZW1

1.26e-052124229470543
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

1.26e-052124217761684
Pubmed

Halofuginone promotes satellite cell activation and survival in muscular dystrophies.

DYSF DMD

1.26e-052124226454207
Pubmed

Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma.

DYSF DMD

1.26e-052124222682622
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

1.26e-052124231578382
Pubmed

Talin, vinculin and nestin expression in orofacial muscles of dystrophin deficient mdx mice.

NES DMD

1.26e-052124222307364
Pubmed

Roles of tau protein in health and disease.

LGMN MARK1 TTBK2 TTBK1

1.27e-0540124428386764
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

NES BZW2 SPTAN1 MYO18A SDAD1 CRACD LIG3 IGF2R AKAP9 SEC63

1.37e-055031241036217030
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

KNTC1 DHX36 RANBP2 BZW2 POLE SDAD1 UBE4A TTBK2 LIG3 TTBK1 LOXHD1 EIF2B5 BZW1 SEC63 EIF4G3 PARD3

1.39e-0512841241617353931
Pubmed

Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.

NES PRKCI PARD3

1.56e-0514124324859200
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DHX16 TNPO1 NUP50 RANBP2 VRK1 POLE ADNP TBL3 BLM LIG3 ARIH2 BZW1 TAF7 TOP2B

1.63e-0510141241432416067
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

NCAM1 LIG3 AKAP9 CLTB SYT1

1.83e-0590124515033168
Pubmed

IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone.

NES RELN NCAM1

1.95e-0515124319712103
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

CTNNAL1 MARK1 COQ5 CCDC88A IGF2R PRKCI DMD SEC63 PARD3

2.13e-05421124936976175
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

PDE3B BZW2 POLE ZZEF1 BLM LIG3 MGAT5 TNKS1BP1 BZW1 KNL1

2.25e-055331241025544563
Pubmed

HEY1 functions are regulated by its phosphorylation at Ser-68.

SYNE1 CCDC88A AKAP9 SYNE2 TNKS1BP1

2.38e-0595124527129302
Pubmed

Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".

PRDM9 AKAP9 EIF4G3

2.39e-0516124329878059
Pubmed

The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate.

NES RELN PRKCI

2.39e-0516124314758363
Pubmed

Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex.

NES RELN TERF2IP

2.90e-0517124321315259
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KDM4C SYNE1 ADNP AKAP9 ARAP1

3.20e-0510112459872452
Pubmed

Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming.

DYSF DMD

3.77e-053124231852847
Pubmed

DNA repair and cell cycle checkpoint defects in a mouse model of 'BRCAness' are partially rescued by 53BP1 deletion.

BLM TP53BP1

3.77e-053124229620483
Pubmed

Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases.

DHX36 BLM

3.77e-053124227407146
Pubmed

Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.

BZW2 BZW1

3.77e-053124234260931
Pubmed

Identification of human Rap1: implications for telomere evolution.

TERF2 TERF2IP

3.77e-053124210850490
Pubmed

USP37 regulates DNA damage response through stabilizing and deubiquitinating BLM.

USP37 BLM

3.77e-053124234606619
Pubmed

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage.

VRK1 TP53BP1

3.77e-053124222621922
InteractionMECP2 interactions

DHX16 TNPO1 DHX36 NUP50 NES RANBP2 RELN VRK1 MARK1 ZNF618 SYNE1 SPTAN1 HECTD4 MYO18A TFIP11 ADNP TERF2 SDAD1 BLM LIG3 SNRNP48 RBAK TNKS1BP1 SEC63 TOP2B TP53BP1

5.18e-08128712326int:MECP2
InteractionDISC1 interactions

DHX36 SYNE1 SPTAN1 TFIP11 CCDC141 TRIM52 CCDC88A IGF2R AKAP9 FEZ1 ARIH2 CTNNA3 KIF3C DMD CCDC102B

5.64e-0842912315int:DISC1
InteractionSIGLECL1 interactions

TNPO1 KNTC1 RANBP6 DEPDC1 UBE4A EIF2B5 MIGA1 EIF4G3

4.59e-071131238int:SIGLECL1
InteractionPCNT interactions

TCHP SYNE1 SPTAN1 TRIM52 LATS1 AKAP9 FEZ1 EIF4G3 TP53BP1 NIN

2.28e-0624112310int:PCNT
InteractionEFNB1 interactions

TNPO1 KNTC1 RELN RANBP6 TFIP11 DEPDC1 UBE4A EIF2B5 MIGA1 EIF4G3

3.78e-0625512310int:EFNB1
InteractionCOMTD1 interactions

TNPO1 KNTC1 RANBP2 RANBP6 TFIP11 EIF2B5 MIGA1 BZW1 EIF4G3

3.87e-062001239int:COMTD1
InteractionKCNA3 interactions

TNPO1 RANBP2 CTNNAL1 BZW2 MYO18A SYAP1 SDAD1 CCDC88A LATS1 IGF2R CTNNA3 TNKS1BP1 BZW1 CRYBG3 SEC63 TAF7 EIF4G3 PARD3

5.67e-0687112318int:KCNA3
InteractionPACC1 interactions

TNPO1 KNTC1 BZW2 RANBP6 EIF2B5 MIGA1 BZW1

8.45e-061191237int:PACC1
InteractionTNRC6A interactions

TNPO1 NES TCHP LATS1 ARIH2 CLTB TNKS1BP1 SEC63 TP53BP1 NIN

8.61e-0628012310int:TNRC6A
InteractionNUBP1 interactions

ZNF618 POLE ADNP SYAP1 CCDC88A ARIH2

8.83e-06791236int:NUBP1
InteractionRIF1 interactions

VRK1 KDM4C USP37 TERF2IP BLM LATS1 FEZ1 ASF1A TP53BP1

1.00e-052251239int:RIF1
InteractionSIRT7 interactions

DHX16 TNPO1 DHX36 NES RANBP2 POLE SPTAN1 ADNP TTF1 TBL3 BLM IGF2R SYNE2 TNKS1BP1 EIF4G3 TP53BP1

1.21e-0574412316int:SIRT7
InteractionBRIP1 interactions

NUP50 USP37 TERF2IP TRIM52 BLM ASF1A

2.12e-05921236int:BRIP1
InteractionGYPB interactions

BZW2 RANBP6 UBE4A EIF2B5 BZW1

2.32e-05561235int:GYPB
InteractionNUP43 interactions

NUP50 RANBP2 TERF2 TTF1 TBL3 SDAD1 BLM LIG3 CCDC88A SYNE2 EIF2B5 EIF4G3 TOP2B KNL1

2.83e-0562512314int:NUP43
InteractionMYOM1 interactions

SYNE1 TFIP11 DYSF LATS1

3.66e-05311234int:MYOM1
InteractionYWHAH interactions

LGMN NES PDE3B MARK1 SPTAN1 HECTD4 MDM4 NEDD4 CCDC88A LATS1 AKAP9 SYNE2 PRKCI TNKS1BP1 CRYBG3 EIF4G3 PARD3 KIF1C NIN

3.86e-05110212319int:YWHAH
InteractionCBX3 interactions

DHX16 VRK1 POGK USP37 ADNP SYAP1 TERF2IP BLM LIG3 RBAK TNKS1BP1 TOP2B TP53BP1 KNL1

4.06e-0564612314int:CBX3
InteractionSLU7 interactions

NES TFIP11 TERF2IP LATS1 AKAP9 CEP70 ASF1A

4.88e-051561237int:SLU7
InteractionBTNL9 interactions

TNPO1 KNTC1 BZW2 TFIP11 EIF2B5 MIGA1 EIF4G3

4.88e-051561237int:BTNL9
InteractionBIRC3 interactions

DHX16 KNTC1 DHX36 NUP50 RANBP2 VRK1 SYNE1 SPTAN1 DUOX2 APOB PRDM7 SUCLA2 SYAP1 TBL3 UBE4A LIG3 KIF3C BZW1 SEC63 ASF1A TOP2B

5.45e-05133412321int:BIRC3
InteractionGPR17 interactions

KNTC1 BZW2 COQ5 RANBP6 TFIP11 UBE4A EIF2B5 MIGA1 BZW1

6.09e-052831239int:GPR17
InteractionCIT interactions

DHX16 DHX36 NUP50 NES RANBP2 VRK1 SYNE1 SPTAN1 MYO18A DUOX2 TFIP11 APOB ADNP ZZEF1 TBL3 LIG3 AKAP9 SYNE2 TNKS1BP1 PARD3 TOP2B NIN

6.12e-05145012322int:CIT
InteractionKIF20A interactions

DHX16 NES RANBP2 SYNE1 SPTAN1 HECTD4 MYO18A TFIP11 APOB TBL3 BLM FER1L4 SYNE2 EIF2B5 ZSCAN2 CRYBG3 PARD3 TOP2B

6.96e-05105212318int:KIF20A
InteractionKPNA4 interactions

TNPO1 DMTF1 NUP50 RANBP2 ADNP TERF2IP SEC63 PARD3

7.30e-052251238int:KPNA4
InteractionTOP2A interactions

DHX16 RANBP2 VRK1 POLE DUOX2 MDM4 TERF2 TERF2IP TRIM52 BLM BZW1 TOP2B

8.23e-0552012312int:TOP2A
InteractionDHX38 interactions

DHX16 NUP50 SYAP1 TERF2IP WBP4 PRKCI TP53BP1

8.39e-051701237int:DHX38
InteractionAPEX1 interactions

DHX16 DHX36 NUP50 BZW2 KDM4C SH3GLB2 MDM4 TERF2 SDAD1 TERF2IP NEDD4 BLM LIG3 ZSCAN32 LATS1 ARIH2 EIF2B5 EIF4G3 TOP2B TP53BP1

8.45e-05127112320int:APEX1
InteractionUTP14A interactions

NUP50 TFIP11 TERF2IP SNRNP48 ARIH2 CEP70 TOP2B NIN

8.51e-052301238int:UTP14A
InteractionARMCX1 interactions

TFIP11 LATS1 CEP70

9.57e-05151233int:ARMCX1
InteractionEPHA1 interactions

TNPO1 KNTC1 SYNE1 CCDC88A EIF2B5 MIGA1 EIF4G3 PARD3

9.88e-052351238int:EPHA1
InteractionMGA interactions

ADNP TERF2IP TRIM52 LATS1 TAF7 ASF1A TP53BP1 NIN

1.14e-042401238int:MGA
InteractionH3C1 interactions

NUP50 VRK1 BZW2 KDM4C SYNE1 SPTAN1 MYO18A ADNP ZZEF1 SDAD1 BLM LIG3 WDR87 ASF1A TOP2B TP53BP1

1.19e-0490112316int:H3C1
InteractionSMARCC1 interactions

TNPO1 SAMD9 SPTAN1 TERF2IP NEDD4 LATS1 BZW1 ASF1A TOP2B TP53BP1

1.25e-0438412310int:SMARCC1
InteractionNBN interactions

VRK1 MDM4 TERF2 TERF2IP BLM LIG3 TP53BP1

1.33e-041831237int:NBN
InteractionZSCAN21 interactions

NUP50 ZSCAN32 ZSCAN20 RBAK CEP70 ZNF287

1.35e-041281236int:ZSCAN21
InteractionZSCAN18 interactions

NUP50 TERF2IP ZSCAN32 ZSCAN20

1.62e-04451234int:ZSCAN18
InteractionKCNQ2 interactions

RANBP2 SPTAN1 ARIH2 SYT1 KCNS2

1.64e-04841235int:KCNQ2
InteractionTAF1 interactions

NUP50 RANBP2 SPTAN1 USP37 DYSF TERF2IP TAF7 ASF1A

1.98e-042601238int:TAF1
InteractionRAB35 interactions

PDE3B MARK1 SPTAN1 NCAM1 DMXL1 CCDC88A LATS1 IGF2R SYNE2 TNKS1BP1 SEC63 PARD3

2.03e-0457312312int:RAB35
InteractionDMD interactions

CTNNAL1 SYNE1 TERF2 NEDD4 SYNE2 DMD

2.29e-041411236int:DMD
InteractionZNF197 interactions

SPTAN1 ZSCAN32 ZSCAN20

2.34e-04201233int:ZNF197
InteractionNUP50 interactions

DHX16 TNPO1 DHX36 NUP50 RANBP2 TFIP11 TERF2IP BLM TP53BP1

2.48e-043411239int:NUP50
InteractionLRRC17 interactions

RANBP6 ZZEF1 PRKCI

2.72e-04211233int:LRRC17
InteractionHSD3B2 interactions

VRK1 TBL3 TOP2B

2.72e-04211233int:HSD3B2
InteractionTFIP11 interactions

DHX16 NUP50 TFIP11 TERF2 SNRNP48 LATS1 WBP4 ARIH2 KIF3C CCDC102B

2.93e-0442712310int:TFIP11
InteractionSTX4 interactions

SYNE1 SPTAN1 SH3GLB2 SYAP1 CCDC88A IGF2R SYNE2 SYT1 SEC63 PARD3

2.98e-0442812310int:STX4
InteractionCCDC68 interactions

TFIP11 AKAP9 NIN

3.14e-04221233int:CCDC68
InteractionS100P interactions

TCHP POGK TFIP11 TERF2IP SNRNP48 CCDC88A KNL1 KIF1C

3.18e-042791238int:S100P
InteractionSMARCC2 interactions

NUP50 SAMD9 SPTAN1 ADNP TERF2IP BZW1 ASF1A TOP2B TP53BP1

3.20e-043531239int:SMARCC2
InteractionH2BC21 interactions

TNPO1 NUP50 VRK1 DUOX2 ARHGAP30 ADNP TERF2 TTF1 BLM LIG3 OTOF TOP2B CFAP46

3.34e-0469612313int:H2BC21
InteractionNXNL1 interactions

TERF2 TERF2IP

3.65e-0451232int:NXNL1
InteractionLATS1 interactions

TCHP SPTAN1 TFIP11 NEDD4 CCDC88A LATS1 AKAP9 CEP70 PARD3 NIN

3.71e-0444012310int:LATS1
InteractionSUMO1 interactions

DHX16 RANBP2 USP25 BLM AKAP9 TOP2B TP53BP1 NIN

3.84e-042871238int:SUMO1
InteractionZNF445 interactions

TRIM52 ZSCAN20 EIF2B5 ZNF287

4.06e-04571234int:ZNF445
InteractionODAD4 interactions

RANBP2 ZZEF1 CEP70

4.09e-04241233int:ODAD4
InteractionDES interactions

NES SPTAN1 TFIP11 DYSF LATS1 KIF1C

4.22e-041581236int:DES
InteractionZFPL1 interactions

CTNNAL1 BZW2 SPTAN1 RANBP6 SYAP1 CCDC88A IGF2R SYT1 TNKS1BP1 PARD3

4.27e-0444812310int:ZFPL1
InteractionOTUD7A interactions

OTUD5 SPTAN1 CCDC88A TNKS1BP1

4.35e-04581234int:OTUD7A
InteractionCILK1 interactions

SPTAN1 DEPDC1 BLM NIN

4.35e-04581234int:CILK1
InteractionSTK4 interactions

SH3GLB2 DMXL1 NEDD4 LATS1 AKAP9 KIF3C

4.36e-041591236int:STK4
InteractionGLI1 interactions

USP37 CRACD SYNE2 CEP70 PRKCI ZNF287

4.36e-041591236int:GLI1
InteractionRPA4 interactions

NUP50 RANBP2 SPTAN1 ADNP SYAP1 BLM LIG3 SEC63 PARD3 KNL1

4.58e-0445212310int:RPA4
InteractionRAD50 interactions

RANBP2 VRK1 MDM4 TERF2 TERF2IP BLM KLHL34 TOP2B TP53BP1

4.59e-043711239int:RAD50
InteractionCACNB4 interactions

TBL3 SYT1 CCDC102B

4.63e-04251233int:CACNB4
InteractionTNKS interactions

USP25 TERF2 TMEM44 WBP4 TNKS1BP1

4.63e-041051235int:TNKS
GeneFamilyFerlin family

DYSF OTOF FER1L4

1.47e-066773828
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

DMTF1 TERF2 TTF1 ZSCAN20

7.60e-0553774532
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

1.07e-0447721252
GeneFamilyMyb/SANT domain containing|Shelterin complex

TERF2 TERF2IP

2.66e-0467721334
GeneFamilyHelix-turn-helix CENPB type domain containing

POGK JRKL

1.35e-0313772533
GeneFamilyDEAH-box helicases

DHX16 DHX36

2.07e-0316772500
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM7 PRDM9

2.34e-03177721197
GeneFamilyEF-hand domain containing

SPTAN1 DUOX2 ZZEF1 RYR3 NIN

2.43e-03219775863
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZZEF1 DMD

2.62e-031877291
GeneFamilyNucleoporins

NUP50 RANBP2

8.18e-03327721051
GeneFamilyTudor domain containing

KDM4C TP53BP1

1.08e-0237772780
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF618 PRDM7 ZSCAN32 PRDM9 ZSCAN20 RBAK ZSCAN2 ZNF287

1.12e-0271877828
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TNPO1 KNTC1 DHX36 VRK1 CTNNAL1 USP25 DEPDC1 SDAD1 DMXL1 BLM CCDC88A SYNE2 WBP4 CEP70 SEC63 TOP2B KNL1 NIN

2.05e-0965612418M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DPYD RANBP2 VRK1 KDM4C ADNP ZZEF1 NEDD4 BLM MGAT5 IGF2R AKAP9 SYNE2 WBP4 PRKCI CRYBG3 DMD EIF4G3 PARD3 TP53BP1

2.18e-0885612419M4500
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL

KNTC1 NUP50 VRK1 PDE3B CTNNAL1 POLE SH3GLB2 DEPDC1 USP37 TTF1 BLM SNRNP48 CCDC88A SYNE2 WBP4 ASF1A KNL1 NIN

4.63e-0793912418M45768
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_NK_CELL

KNTC1 NUP50 VRK1 CTNNAL1 TCHP POLE SH3GLB2 DEPDC1 USP37 TBL3 BLM CCDC88A SYNE2 KNL1

5.43e-0669412414M45767
CoexpressionGSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_UP

DHX36 RELN ZZEF1 TERF2IP SLC6A12 MGAT5 KNL1

3.24e-051881247M8452
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN

TNPO1 NCAM1 TFIP11 SUCLA2 BLM IGF2R MCTP2

4.51e-051981247M4424
CoexpressionGSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN

DHX16 DHX36 PDE3B CTNNAL1 IGF2R SYNE2 EIF2B5

4.80e-052001247M9327
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_LARGE_PRE_B_CELL

KNTC1 NUP50 VRK1 CTNNAL1 TCHP POLE DEPDC1 SUCLA2 TTF1 TBL3 BLM SNRNP48 CCDC88A SYNE2 WBP4 CEP70 ASF1A KNL1

7.50e-05136312418M45782
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DMTF1 RANBP2 SAMD9 OTUD5 SYNE1 SPTAN1 HECTD4 USP25 ARHGAP30 MDM4 TERF2IP CCDC88A LATS1 AKAP9 BZW1 TAF7 ASF1A TOP2B NIN

7.52e-05149212419M40023
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

DPYD RANBP2 PDE3B POGK HECTD4 USP25 NCAM1 TTF1 PRDM9 LATS1 AKAP9 FEZ1 SYNE2 CLTB DMD TOP2B ZNF287

1.84e-0765412117Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

DHX36 NUP50 PDE3B ZNF618 POLE COQ5 DEPDC1 ADNP TTF1 BLM CRACD PRDM9 SNRNP48 CCDC88A AKAP9 SYNE2 CEP70 DMD SEC63 ASF1A TP53BP1 ZNF287 KNL1

5.88e-07125712123facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

DHX36 NUP50 NES PDE3B ZNF618 POLE COQ5 DEPDC1 ADNP TTF1 BLM CRACD PRDM9 SNRNP48 CCDC88A AKAP9 FEZ1 SYNE2 CEP70 DMD SEC63 ASF1A TP53BP1 ZNF287 KNL1

5.90e-07145912125facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

USP37 UBE4A CCDC88A LATS1 AKAP9 CEP70 SEC63 KNL1

1.15e-051861218Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

DHX36 RANBP2 BLM CCDC88A LATS1 AKAP9 SYNE2 CEP70 TOP2B KNL1

1.19e-0531112110Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

DHX36 NES RANBP2 POGK BLM CRACD TTBK2 AMMECR1L CCDC88A LATS1 AKAP9 SYNE2 CEP70 DMD CCDC181 TAF7 TOP2B KNL1

1.25e-0598912118Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#3

USP37 UBE4A CCDC88A LATS1 AKAP9 FEZ1 DMD SEC63 KNL1

2.56e-052711219Facebase_RNAseq_e10.5_Mandibular Arch_1000_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

DHX36 RELN PDE3B MARK1 ZNF618 DEPDC1 TTF1 BLM CRACD PRDM9 CCDC88A AKAP9 SYNE2 CEP70 DMD TP53BP1 KNL1

1.07e-04106012117facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

DPYD RANBP2 USP25 PRDM9 LATS1 AKAP9 FEZ1 SYNE2 DMD

1.11e-043281219Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

DHX36 NES RELN PDE3B MARK1 ZNF618 DEPDC1 TTF1 BLM CRACD PRDM9 CCDC88A AKAP9 FEZ1 FER1L4 SYNE2 CEP70 DMD TP53BP1 KNL1

1.40e-04141412120facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasNK cells, NK.MCMV1.Sp, CD3-,NK1.1+, Spleen, avg-3

KNTC1 POGK POLE USP25 BLM IGF2R TNKS1BP1 MCTP2 KNL1

2.57e-043671219GSM538309_500
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

KNTC1 NUP50 NES RELN OTUD5 COQ5 SPTAN1 USP37 CRACD PRDM9 CCDC88A AKAP9 FEZ1 SYNE2 WBP4 DMD TOP2B TP53BP1 KNL1

2.70e-04137012119facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

TNPO1 RANBP2 PDE3B USP37 LATS1 IGF2R AKAP9 MIGA1 CRYBG3

3.78e-091931249abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 NCAM1 DEPDC1 SLC6A12 SYNE2 KNL1 NIN

7.69e-071811247566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 NCAM1 DEPDC1 SLC6A12 SYNE2 KNL1 NIN

7.69e-071811247db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

DHX36 NCAM1 CCDC88A AKAP9 SYT1 SEC63 TOP2B

1.40e-061981247de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMTF1 PDE3B SYNE1 MDM4 AKAP9 SYNE2 MCTP2

1.45e-061991247f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

CCDC88A AKAP9 SYNE2 PRKCI SEC63 EIF4G3 PARD3

1.45e-06199124718a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DPYD KDM4C USP25 MGAT5 DMD EIF4G3 PARD3

1.45e-06199124794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellmild-NK|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SAMD9 SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.50e-062001247a11fb1d7e124c352eb73fea0e0ec0fed577c97f7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

RELN ZNF618 NCAM1 CRACD CCDC88A AKAP9 FEZ1

1.50e-062001247c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellsevere-NK|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 BZW1 MCTP2

1.50e-062001247d6767f06fe13be8110a86c2a6029be2dd9ce666c
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_only / Treatment groups by lineage, cell group, cell type

NES MARK1 SYNE1 NCAM1 CTNNA3 DMD CCDC102B

1.50e-0620012477c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCHP POGK BLM FAM204A LIG3 KNL1

3.86e-06149124665778f19599b4955c0a16f0121237656449431fb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 VRK1 POLE DEPDC1 BLM KNL1

7.95e-061691246e7514956b2e4298222ec443f98b2f5289451786e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES HECTD4 SLC6A12 DMD CCDC102B MCTP2

8.23e-0617012465570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RANBP2 PDE3B SYNE1 APOB AKAP9 SYNE2

8.51e-0617112462e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CTNNAL1 SH3GLB2 DYSF RYR3 ZSCAN2

9.71e-0617512460801cccec6915aefc135262fc74580280fd51aa5
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CTNNAL1 SH3GLB2 DYSF RYR3 ZSCAN2

9.71e-06175124609163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES RANBP2 SYNE1 AKAP9 SYNE2 TAF7

1.07e-05178124601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES MARK1 SYNE1 CTNNA3 DMD CCDC102B

1.37e-0518612464780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 NCAM1 USP37 NEDD4 SYNE2 NIN

1.41e-05187124614c239af77116d28d511dea754b6150d20488080
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADNP AMMECR1L MGAT5 IGF2R ZSCAN2 KIF3C

1.46e-05188124614bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NWD1 DYSF SYT1 KIF3C CFAP46

1.46e-051881246524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN NWD1 DYSF SYT1 KIF3C CFAP46

1.46e-051881246d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMTF1 PDE3B SYNE1 NCAM1 SYNE2 MCTP2

1.55e-051901246d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PDE3B TBL3 ZSCAN32 ARAP1 CFAP46 NIN

1.64e-051921246445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCAM1 CRACD LOXHD1 SYT1 DMD CCDC102B

1.69e-051931246f1199518c3626fd29bfce65070dd21a660671213
ToppCellCD8+_Memory_T_cell-CV-0|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

DPYD PDE3B SYNE1 SPTAN1 TCP11L2 SYNE2

1.69e-051931246995781d87a919c0380750878bafe584342bb83ad
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KNTC1 VRK1 POLE DEPDC1 BLM KNL1

1.69e-0519312464b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGMN RELN CCDC141 BLM CRACD OTOF

1.69e-051931246e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DMTF1 SAMD9 SYNE1 TRIM52 MCTP2 TP53BP1

1.74e-0519412466be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell3'_v3-bone_marrow-Lymphocytic_NK-NK_CD16|bone_marrow / Manually curated celltypes from each tissue

SYNE1 NCAM1 SYAP1 IGF2R SYNE2 MCTP2

1.74e-0519412467773501e076d470158dbc1d7f10c67152b326eb7
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

SYNE1 NCAM1 IGF2R SYNE2 EIF4G3 MCTP2

1.74e-051941246335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell3'_v3-blood-Lymphocytic_NK|blood / Manually curated celltypes from each tissue

SYNE1 NCAM1 SYAP1 FEZ1 BZW1 MCTP2

1.79e-051951246731a454e45c7b610e0140312bcabaea711dcc766
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 STK33 SYNE2 PARD3 MCTP2 CFAP46

1.85e-051961246af4cdc61830685a888a1209826c23bcf54a43084
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.85e-0519612465b5cf6f70534661d694f47359b6595b4580876c3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.85e-0519612468e1ed30256a031bb90dac1f167e074c68efbed74
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 STK33 SYNE2 PARD3 MCTP2 CFAP46

1.85e-0519612466d02d494196e3f857d53eea46d9419690d43beca
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16|lymph-node_spleen / Manually curated celltypes from each tissue

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.85e-051961246f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.85e-051961246f0566f2ef96584ed6d9247b149218376fb509915
ToppCell10x5'-bone_marrow-Lymphocytic_NK-NK_CD16|bone_marrow / Manually curated celltypes from each tissue

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.85e-051961246a3b077e82b1550eb328c84b567b60179001f9a77
ToppCellCOVID-19_Severe-NK|World / disease group, cell group and cell class

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.85e-051961246f46ca7cc2d8407d0dcaa77c4b16a2c1f2a23734d
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DHX36 PDE3B KDM4C SYNE1 AKAP9 SYNE2

1.90e-05197124657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.90e-0519712464e141dfb094e10383d815fc7108b11a0584c3a4b
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 AKAP9 STK33 SYNE2 DMD CFAP46

1.90e-05197124674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.90e-05197124608286770c0b707a7a4436ea8d4416ddfbfe2dc0c
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

SYNE1 POLE MGAT5 SYNE2 TNKS1BP1 EIF4G3

1.95e-05198124676d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.95e-051981246d7053a898e04478c577381085f615edaad3cdc5b
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.95e-0519812460e918e9db9b884f5328d438e90efe065e27266ee
ToppCellmild_COVID-19-NK|World / disease group, cell group and cell class (v2)

SYNE1 NCAM1 SYAP1 FEZ1 SYNE2 MCTP2

1.95e-051981246c0334e31772ab691be29cbaa78e43ee3b00425f5
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.95e-051981246ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.95e-051981246fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

1.95e-051981246aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

1.95e-0519812461ef3a6bd681c223eed58300348adfef89df5563c
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

2.01e-051991246edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellCOVID-19_Moderate-NK|COVID-19_Moderate / disease group, cell group and cell class

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-051991246e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.

CRACD CCDC88A IGF2R AKAP9 FEZ1 SYT1

2.01e-051991246b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / disease group, cell group and cell class

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

2.01e-051991246bda28d975f4017ec5bded1d3c72310eabc5aac07
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-0519912464820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-051991246eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-05199124610c8729b779073c3bf808e85958d59147f0be5c5
ToppCellControl-NK|Control / Disease condition and Cell class

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-051991246f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-051991246867fd292f3879982422e840e087bfdb3b21a8715
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-0519912465e9fe852a70546c9d235414a2c26ca3e67ba6eb9
ToppCellControl-Lymphoid_T/NK-NK|Control / Disease group, lineage and cell class

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-05199124694b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.01e-051991246d2c9fb69e5ef75778a1652da293fcf8cfa7ecfcc
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KNTC1 POLE DEPDC1 SYNE2 CEP70 KNL1

2.01e-051991246be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN SAMD9 BLM CRACD OTOF PARD3

2.07e-052001246a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KNTC1 POLE DEPDC1 CCDC88A CEP70 KNL1

2.07e-0520012464cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KNTC1 POLE DEPDC1 CCDC88A CEP70 KNL1

2.07e-0520012469bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 CTNNA3 SYT1 DMD CCDC102B MCTP2

2.07e-052001246f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN SAMD9 BLM CRACD OTOF PARD3

2.07e-05200124633b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MARK1 SYNE1 NCAM1 CTNNA3 DMD CCDC102B

2.07e-052001246a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NES MARK1 SYNE1 CTNNA3 DMD CCDC102B

2.07e-052001246c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellControl-Control-Lymphocyte-T/NK-NK|Control / Disease, condition lineage and cell class

SYNE1 NCAM1 IGF2R FEZ1 SYNE2 MCTP2

2.07e-052001246c64c27dbf4df42ca2ad2bd94b50fab87b4050ef3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

SPTAN1 HECTD4 NCAM1 ADNP KIF3C EIF4G3

2.07e-052001246c92e4fc0442404481fcac623d691dae6215b852d
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NES PDE3B CTNNAL1 SPTAN1 NEDD4 SYNE2

2.07e-05200124679e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

BZW2 SPTAN1 NCAM1 FEZ1 SYT1 KIF3C

2.07e-052001246af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

DPYD BZW2 SPTAN1 NCAM1 AKAP9 SYT1

2.07e-05200124619055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

SAMD9 SYNE1 NCAM1 FEZ1 SYNE2 MCTP2

2.07e-0520012466a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SAMD9 SYNE1 NCAM1 IGF2R SYNE2 EIF4G3

2.07e-0520012462281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron|5w / Sample Type, Dataset, Time_group, and Cell type.

RELN SPTAN1 NCAM1 TERF2IP AKAP9 SYT1

2.07e-052001246c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

RELN SAMD9 BLM CRACD OTOF PARD3

2.07e-0520012469719fabddc34051949468a7520289e3c750de4f8
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

NES SYNE1 NCAM1 CTNNA3 DMD CCDC102B

2.07e-052001246b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

RELN NWD1 PRDM9 CTNNA3 DMD

3.07e-05129124557b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma|TCGA-Uterus / Sample_Type by Project: Shred V9

NWD1 POGK USP37 AKAP9 TAF7

6.51e-0515112452810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 POLE DEPDC1 WDR87 KNL1

6.92e-051531245d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 POLE DEPDC1 WDR87 KNL1

6.92e-05153124554a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 POLE DEPDC1 WDR87 KNL1

6.92e-05153124569a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KNTC1 POLE DEPDC1 WDR87 KNL1

6.92e-051531245e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VRK1 USP25 ARHGAP30 DEPDC1 KNL1

7.82e-051571245904cd98ae85ed6459e0663f077ac462842bf12df
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 ARHGAP30 DEPDC1 MCTP2 KNL1

7.82e-0515712450fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RELN NWD1 CTNNA3 SYT1 DMD

8.30e-0515912455335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellSevere-Lymphoid-NK-Proliferating_T|Severe / Condition, Lineage, Cell class and cell subclass

MYO18A IRAK1BP1 NCAM1 RBAK KLHL34

8.55e-051601245cb2276d9bd78508644420e9580d3c17b914224cb
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

CCDC141 SDAD1 PRKCI KIF3C ASF1A

8.81e-051611245a114f4f75859d9ef900e5146686438d051241429
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

GABRG1 NWD1 RYR3 WDR87 CCDC181

9.61e-0516412450e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VRK1 DEPDC1 BLM CCDC88A KNL1

1.08e-041681245b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 VRK1 POLE DEPDC1 BLM

1.11e-041691245121768fc51fc3441ec725346a1bbe29e21d05971
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VRK1 ARHGAP30 DEPDC1 CCDC88A KNL1

1.14e-0417012459e94fa0d05abed3438b28296a293767096d517d6
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 RYR3 OTOF WDR87 SYT1

1.17e-04171124582de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTNNAL1 RYR3 OTOF WDR87 SYT1

1.17e-04171124509e653973962fb884878089d281f0947f7a285f6
Drugdiphenylamine-2-carboxylate

GJB4 TFIP11 MDM4 TBL3 BLM LIG3 KIF3C DMD TOP2B

2.93e-071641249CID000004386
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

DYSF OTOF FER1L4

2.10e-0671173DOID:11724 (implicated_via_orthology)
Diseasetriglycerides in large LDL measurement

APOB IGF2R SYNE2 TP53BP1

2.57e-05431174EFO_0022319
Diseasealpha-tocopherol measurement

KDM4C MGAT5 STK33

6.59e-05201173EFO_0007898
Diseasetriglycerides in LDL measurement

APOB IGF2R SYNE2 TP53BP1

7.35e-05561174EFO_0022320
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

9.30e-0541172cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.55e-0451172C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

1.55e-0451172C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

2.31e-0461172cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

2.31e-0461172C0410189
DiseaseLarge cell carcinoma of lung

TTBK1 LATS1 STK33

2.77e-04321173C0345958
DiseaseQT interval

TCHP RANBP6 SUCLA2 CCDC141 LIG3 AMMECR1L TMEM44 ARIH2 MIGA1

2.85e-045341179EFO_0004682
Diseaseacisoga measurement

IGF2R KIF1C

3.23e-0471172EFO_0800068
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

3.23e-0471172C0751337
DiseaseVentricular Dysfunction

IGF2R DMD

4.30e-0481172C0242973
Diseasemortality

PDE3B NCAM1 DEPDC1 DMD NIN

6.45e-041731175EFO_0004352
Diseaseschizophrenia (is_marker_for)

RELN NCAM1 FEZ1

7.15e-04441173DOID:5419 (is_marker_for)
Diseasedelta-5 desaturase measurement

NEDD4 BLM

8.38e-04111172EFO_0007764
Diseasekidney cancer (implicated_via_orthology)

POLE LATS1

8.38e-04111172DOID:263 (implicated_via_orthology)
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.00e-03121172DOID:11726 (implicated_via_orthology)
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

APOB IGF2R SYNE2 TP53BP1

1.01e-031111174EFO_0004530, EFO_0008595
DiseaseMalignant neoplasm of breast

DPYD SYNE1 SPTAN1 MDM4 DYSF NEDD4 AKAP9 OTOF SYNE2 WBP4 DMD TP53BP1

1.17e-03107411712C0006142
Diseasetotal lipids in medium VLDL

APOB IGF2R TP53BP1

1.30e-03541173EFO_0022153
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

DPYD EIF2B5

1.38e-03141172C1858991
Diseasevitamin K-dependent protein C measurement

AMMECR1L PARD3

1.58e-03151172EFO_0008318
Diseasetriglycerides in IDL measurement

APOB IGF2R TP53BP1

1.60e-03581173EFO_0022149
Diseasephospholipids in VLDL measurement

APOB IGF2R TP53BP1

1.68e-03591173EFO_0022301
Diseasetuberculosis

BZW2 KDM4C NEDD4 SYT1 DMD

1.73e-032161175MONDO_0018076
Diseasetotal lipids in VLDL measurement

APOB IGF2R TP53BP1

1.76e-03601173EFO_0022314
Diseasetea consumption measurement

VRK1 KDM4C ZNF618 HECTD4

1.77e-031291174EFO_0010091
Diseasefree cholesterol in VLDL measurement

APOB IGF2R TP53BP1

1.85e-03611173EFO_0022276
Diseasetriglycerides in medium LDL measurement

APOB IGF2R TP53BP1

1.94e-03621173EFO_0022322
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 DYSF

2.04e-03171172DOID:9884 (is_implicated_in)
Diseaseposterior cingulate cortex volume measurement

KDM4C NIN

2.04e-03171172EFO_0010324
Diseasecholesterol in large VLDL measurement

APOB IGF2R TP53BP1

2.22e-03651173EFO_0021902
Diseasecholesterol in very large VLDL measurement

APOB IGF2R TP53BP1

2.22e-03651173EFO_0022230
Diseaseeosinophil count

DHX16 TCHP KDM4C HECTD4 RANBP6 MDM4 ERN2 DYSF MGAT5 AKAP9 PRKCI TNKS1BP1 EIF4G3 TP53BP1

2.31e-03148811714EFO_0004842
Diseasetotal lipids in small VLDL

APOB IGF2R TP53BP1

2.42e-03671173EFO_0022148
Diseasetriglycerides in very small VLDL measurement

APOB IGF2R TP53BP1

2.52e-03681173EFO_0022144
Diseaseinosine measurement

CTNNA3 DMD

2.55e-03191172EFO_0010503
DiseaseStomach Carcinoma

TCHP POLE

3.12e-03211172C0699791
Diseasemuscular dystrophy (implicated_via_orthology)

DYSF DMD

3.12e-03211172DOID:9884 (implicated_via_orthology)
Diseasepulse pressure measurement

TCHP ZNF618 NCAM1 SUCLA2 DYSF CCDC141 TERF2 LIG3 PRDM9 TTBK1 CTNNA3 SYT1 NIN

3.54e-03139211713EFO_0005763
Diseaseparental longevity

HECTD4 IRAK1BP1 RYR3 MGAT5 IGF2R TCP11L2 ZNF287

3.61e-034941177EFO_0007796
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

APOB IGF2R TP53BP1

3.72e-03781173EFO_0022187

Protein segments in the cluster

PeptideGeneStartEntry
NVEDTNEIDWEDLAS

TTF1

776

Q15361
NASDSEVDQDDVVEW

ADNP

951

Q9H2P0
FVEWLQNAEEESESE

BZW2

401

Q9Y6E2
TADDEDFIWVQENID

AKAP9

3541

Q99996
EVAKEQDWDQIQTID

AMMECR1L

236

Q6DCA0
EDTEDTWDSELQANT

CRYBG3

1326

Q68DQ2
VEWLKNAEEESESEA

BZW1

401

Q7L1Q6
INWEDNTEKLEDAES

ASF1A

151

Q9Y294
EFEDLEWSEEVQKLQ

CCDC96

206

Q2M329
NVLSQTEEEDKEWRA

CFAP46

161

Q8IYW2
TEQDETGKWNEDEDQ

DPYD

411

Q12882
EAEIENLSWKVERAD

ARIH2

451

O95376
DSTQWLEAKEEAEQV

DMD

2581

P11532
SKQQTEKPESEDEWE

DHX16

151

O60231
EVDQELIEDSQWEEI

BPNT1

81

O95861
IAELDVADENDINWD

DMTF1

351

Q9Y222
LKWDSDNDEENEDVP

DMXL1

1966

Q9Y485
AVEEWNIEKAEELSN

FAM204A

161

Q9H8W3
AEKELTDRNWDQEDE

NUP50

6

Q9UKX7
NKVTIWDLAEGEEQD

NWD1

1236

Q149M9
ENTADNEKECIIVWE

RANBP2

2701

P49792
EEEEWELTQNVVAFD

KLHL34

326

Q8N239
KKELVNDDEDIDWVQ

PRKCI

286

P41743
NDDEDIDWVQTEKHV

PRKCI

291

P41743
EETKEWEGQIDDHQS

IRAK1BP1

206

Q5VVH5
LKQSEEELDWSQEEA

MCTP2

96

Q6DN12
EETESVDNRESSENW

NEDD4

671

P46934
SDDTDVEVTSEDEWQ

MDM4

291

O15151
VWTVDLNNQEEVEDA

MGAT5

576

Q09328
KLWSDDNEEENVNDT

LATS1

1046

O95835
FQDVSDWLEKESEQE

ERN2

791

Q76MJ5
VVIWNTEDVVLDDEN

FER1L4

1496

A9Z1Z3
VEKVEIWNDTNEDEF

LOXHD1

1336

Q8IVV2
FEWLADIIQEVEEND

DUOX2

1426

Q9NRD8
FIQWLKEAEEESSED

EIF2B5

706

Q13144
EDNKWERESQETTRE

CCDC88A

1026

Q3V6T2
VIEAWVAEEEDDNNN

KIF3C

426

O14782
TEEQIAAEEAWNETE

MYO18A

336

Q92614
EGDKWLTEEAQSEQQ

PDE3B

636

Q13370
EQEKWDEQSDQESTT

KCNS2

131

Q9ULS6
IDNRELSQEDVEEVW

DEPDC1

176

Q5TB30
ADVQRWEDTVEKDQE

NES

946

P48681
WEDTVEKDQELAQES

NES

951

P48681
ETEKIIAELNETWEE

KIF1C

446

O43896
NEENDARWETKLDEV

KDM4C

661

Q9H3R0
NLEDEEKNNPVEEWD

KNL1

2061

Q8NG31
SEQTEWQQLVDDAKE

KNTC1

446

P50748
EEETLQDEEVWDALT

FEZ1

96

Q99689
ENVTTENLEKWLEVD

JRKL

421

Q9Y4A0
EAEESNVEDLLENNW

POLE

1966

Q07864
FSDEEWEVLTEQQKA

POGK

56

Q9P215
TELEGWEELEDNEKE

LIG3

161

P49916
WEELEDNEKEQITQH

LIG3

166

P49916
VAELEQKWQSEVDDA

HECTD4

961

Q9Y4D8
LSTEDIQEQWSEEFE

RELN

411

P78509
IKLQVDDTEDSDEEW

PRDM9

81

Q9NQV7
EDDFEKDLEWLINEN

CCDC181

16

Q5TID7
KLDAEIEIWDDTSND

CTNNA3

686

Q9UI47
RESDEETQIKVNWEE

APOB

4046

P04114
EQIDLTEEQKDDSEW

BLM

216

P54132
VWELLQEADKTAEEN

CCDC141

81

Q6ZP82
TSDADCEIEKWEDQE

CTNNAL1

576

Q9UBT7
CEIEKWEDQENEIVQ

CTNNAL1

581

Q9UBT7
EKQQEEAEWESINVL

CEP70

21

Q8NHQ1
DEDDEDLTVNKTWVL

GABRG1

41

Q8N1C3
KDNDQETIAVDEWIV

DHX36

921

Q9H2U1
QEEEEAEGWEELEQQ

CRACD

361

Q6ZU35
EEVWDDEQKDFVCNT

GJB4

41

Q9NTQ9
QANSVESEQKEEWDK

MARK1

441

Q9P0L2
LSWEEIAKEYQNEED

COQ5

146

Q5HYK3
QAENTSEWDKREILE

CCDC102B

356

Q68D86
DEEWSTDLNRAVDEQ

DYSF

996

O75923
DEQIFDWVEANLDEI

EIF4G3

1441

O43432
VIIWNTDEVVLEDDD

OTOF

1736

Q9HC10
KRATDWEATNEAIEE

OTUD5

386

Q96G74
WEATNEAIEEQVARE

OTUD5

391

Q96G74
KWLEKQEQDEDGTEE

PARD3

231

Q8TEW0
QGAQEDQVAEEKWEV

ARHGAP30

771

Q7Z6I6
NSWDKADEDDIKLVN

MIGA1

186

Q8NAN2
VNKEEETDENETEWL

IGF2R

2356

P11717
ETDENETEWLMEEIQ

IGF2R

2361

P11717
VTEEWRDLQSAEKEE

SYT1

256

P21579
WEIIAEDETKEAENQ

TAF7

181

Q15545
WKNNPESVEENTTEE

STK33

401

Q9BYT3
WKEAQEKAAEEDETQ

TOP2B

1111

Q02880
DQTTEWIKESVNEEL

TCP11L2

261

Q8N4U5
NKDIADDEVATWIQD

SYNE1

7271

Q8NF91
VEIWEAEAKSVLDQD

SYNE2

746

Q8WXH0
QESAAVEKLEEDWEI

SYNE2

2391

Q8WXH0
VEKLEEDWEINKDSA

SYNE2

2396

Q8WXH0
QREEKSQWEFEKDEL

NIN

851

Q8N4C6
VVDSESSQDEWQDAL

NBPF7P

261

P0C2Y1
NLPENTDDWTKEDVN

SAMD9

6

Q5K651
IKLQVDDTEDSDEEW

PRDM7

81

Q9NQW5
DQEDEDQVKDRGQWT

SLC6A12

26

P48065
ASALWNDEVDKAEQE

SH3GLB2

206

Q9NR46
EDSADWEKELQQELQ

SYAP1

311

Q96A49
TESEKRDENWDKEIE

SYAP1

331

Q96A49
KEENAENDEDGWEST

SDAD1

486

Q9NVU7
VDLQDDEDWVNADEM

RANBP6

321

O60518
LQDWTQEDERDKDAA

SUCLA2

291

Q9P2R7
WLEASEIEDEEEKVS

ARAP1

1051

Q96P48
ELDAASKVTEQEWRE

CLTB

116

P09497
SWTKDGEQIEQEEDD

NCAM1

246

P13591
QLWSKEDEEDQNEEE

TRIM52

46

Q96A61
EAEVWEETDVNRNKL

TTBK1

396

Q5TCY1
ELINEVKESWAEEAD

ZNF618

831

Q5T7W0
EDDSWVQEAVLQEDG

ZSCAN2

36

Q7Z7L9
TFKDVAVDITQEDWE

ZNF287

171

Q9HBT7
SQEQWQESSSEEDLE

ZSCAN20

681

P17040
KENLKWDDSEEVEIN

ZSCAN32

421

Q9NX65
WDDSEEVEINKALQR

ZSCAN32

426

Q9NX65
DKEEEQAEYLWTEVT

RYR3

4356

Q15413
LWKDVTEAEQAEEQA

TBL3

631

Q12788
DFTQEEWQQLDPDEK

RBAK

16

Q9NYW8
DADETKEWIEEKNQA

SPTAN1

1241

Q13813
QDADEQDWEFQKRDV

TNKS1BP1

921

Q9C0C2
EIDSKEWVIVDKEQD

TTBK2

546

Q6IQ55
EWQEIKQEVESHEEV

WBP4

296

O75554
EDNQRFEKELEEWDA

USP25

691

Q9UHP3
QDEKQNKDDEAEWQE

SEC63

601

Q9UGP8
TCAEKEEENQENLDW

TMEM44

341

Q2T9K0
LQAWEADQQEEEEEE

TCHP

446

Q9BT92
QELEHKEQEAWEEAT

TP53BP1

736

Q12888
EIDDDDTISDWNLRK

TNPO1

371

Q92973
EDTEWSNTQTEEAIQ

VRK1

371

Q99986
EQEAWEQKEDDDLKR

USP37

821

Q86T82
ELEEEWDEADVKLQQ

ZZEF1

656

O43149
ISQWSEEDELADAKQ

ZZEF1

1721

O43149
VELEDQDWLDMSNVE

UBE4A

121

Q14139
EELSWKEEELNQEEG

WDR87

1726

Q6ZQQ6
ELSNHWQEEQEKAED

SNRNP48

251

Q6IEG0
WQEEQEKAEDDAEKN

SNRNP48

256

Q6IEG0
SNGVEEKETWVEEDE

TERF2

456

Q15554
EKETWVEEDELFQVQ

TERF2

461

Q15554
EEEAEEEFQKELSQW

TFIP11

211

Q9UBB9
IWSRQDDIDLQKDDE

TERF2IP

361

Q9NYB0
NWMEDSDVEDLTKET

LGMN

236

Q99538