Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptide-glutamate-alpha-N-acetyltransferase activity	NAA11 NAA10	8.58e-06	2	59	2	GO:1990190
GeneOntologyMolecularFunction	peptide-serine-alpha-N-acetyltransferase activity	NAA11 NAA10	2.57e-05	3	59	2	GO:1990189
GeneOntologyMolecularFunction	retinoic acid binding	UGT1A4 UGT1A3 UGT1A5	7.62e-05	28	59	3	GO:0001972
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	UGT1A4 UGT1A3 GCNT7 UGT1A5 UGT8	8.87e-05	153	59	5	GO:0008194
GeneOntologyMolecularFunction	glucuronosyltransferase activity	UGT1A4 UGT1A3 UGT1A5	1.50e-04	35	59	3	GO:0015020
GeneOntologyMolecularFunction	peptide alpha-N-acetyltransferase activity	NAA11 NAA10	2.38e-04	8	59	2	GO:0004596
GeneOntologyMolecularFunction	retinoid binding	UGT1A4 UGT1A3 UGT1A5	3.86e-04	48	59	3	GO:0005501
GeneOntologyMolecularFunction	hexosyltransferase activity	UGT1A4 UGT1A3 GCNT7 UGT1A5 UGT8	3.96e-04	211	59	5	GO:0016758
GeneOntologyMolecularFunction	isoprenoid binding	UGT1A4 UGT1A3 UGT1A5	4.10e-04	49	59	3	GO:0019840
GeneOntologyMolecularFunction	platelet-derived growth factor receptor binding	ITGA5 LYN	1.13e-03	17	59	2	GO:0005161
GeneOntologyMolecularFunction	glycosyltransferase activity	UGT1A4 UGT1A3 GCNT7 UGT1A5 UGT8	1.60e-03	288	59	5	GO:0016757
GeneOntologyBiologicalProcess	cellular glucuronidation	UGT1A4 UGT1A3 UGT1A5	2.85e-05	21	59	3	GO:0052695
GeneOntologyBiologicalProcess	glucuronate metabolic process	UGT1A4 UGT1A3 UGT1A5	5.52e-05	26	59	3	GO:0019585
GeneOntologyBiologicalProcess	uronic acid metabolic process	UGT1A4 UGT1A3 UGT1A5	5.52e-05	26	59	3	GO:0006063
GeneOntologyCellularComponent	NatA complex	NAA11 NAA10	7.79e-05	5	59	2	GO:0031415
GeneOntologyCellularComponent	N-terminal protein acetyltransferase complex	NAA11 NAA10	3.47e-04	10	59	2	GO:0031414
Domain	UDPGT	UGT1A4 UGT1A3 UGT1A5 UGT8	5.16e-07	21	59	4	PF00201
Domain	UDPGT	UGT1A4 UGT1A3 UGT1A5 UGT8	5.16e-07	21	59	4	PS00375
Domain	UDP_glucos_trans	UGT1A4 UGT1A3 UGT1A5 UGT8	5.16e-07	21	59	4	IPR002213
Domain	TPR_2	CTR9 STIP1 TTC3	5.28e-04	50	59	3	PF07719
Domain	TPR_2	CTR9 STIP1 TTC3	5.28e-04	50	59	3	IPR013105
Domain	Acetyltransf_1	NAA11 NAA10	2.38e-03	23	59	2	PF00583
Domain	GNAT	NAA11 NAA10	2.81e-03	25	59	2	PS51186
Domain	GNAT_dom	NAA11 NAA10	2.81e-03	25	59	2	IPR000182
Domain	TPR_1	CTR9 STIP1 TTC3	2.89e-03	90	59	3	PF00515
Domain	TPR_1	CTR9 STIP1 TTC3	2.89e-03	90	59	3	IPR001440
Domain	Sulfotransferase_dom	TPST1 CHST4	5.77e-03	36	59	2	IPR000863
Domain	Sulfotransfer_1	TPST1 CHST4	5.77e-03	36	59	2	PF00685
Domain	Myosin_head_motor_dom	MYH1 MYO9A	6.41e-03	38	59	2	IPR001609
Domain	MYOSIN_MOTOR	MYH1 MYO9A	6.41e-03	38	59	2	PS51456
Domain	Myosin_head	MYH1 MYO9A	6.41e-03	38	59	2	PF00063
Domain	MYSc	MYH1 MYO9A	6.41e-03	38	59	2	SM00242
Domain	-	NAA11 NAA10	7.08e-03	40	59	2	3.40.630.30
Domain	TPR	CTR9 STIP1 TTC3	7.90e-03	129	59	3	SM00028
Domain	TPR_repeat	CTR9 STIP1 TTC3	8.58e-03	133	59	3	IPR019734
Domain	Cyt_P450_E_grp-I	CYP4Z1 CYP21A2	8.90e-03	45	59	2	IPR002401
Domain	Acyl_CoA_acyltransferase	NAA11 NAA10	8.90e-03	45	59	2	IPR016181
Pathway	WP_METAPATHWAY_BIOTRANSFORMATION	UGT1A4 UGT1A3 CYP4Z1 UGT1A5 CHST4 CYP21A2	1.25e-05	153	48	6	MM15844
Pathway	REACTOME_ATORVASTATIN_ADME	UGT1A4 UGT1A3 UGT1A5	1.64e-05	15	48	3	MM15697
Pathway	WP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II	UGT1A4 UGT1A3 CYP4Z1 UGT1A5 CHST4 CYP21A2	3.44e-05	183	48	6	M39588
Pathway	KEGG_STEROID_HORMONE_BIOSYNTHESIS	UGT1A4 UGT1A3 UGT1A5 CYP21A2	3.55e-05	55	48	4	M14933
Pathway	REACTOME_HEME_DEGRADATION	UGT1A4 UGT1A3 UGT1A5	4.06e-05	20	48	3	MM14721
Pathway	REACTOME_PREDNISONE_ADME	UGT1A4 UGT1A3 UGT1A5	6.25e-05	23	48	3	MM16639
Pathway	REACTOME_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	7.13e-05	24	48	3	MM14599
Pathway	REACTOME_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	8.08e-05	25	48	3	M17787
Pathway	WP_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	8.08e-05	25	48	3	MM15820
Pathway	KEGG_ASCORBATE_AND_ALDARATE_METABOLISM	UGT1A4 UGT1A3 UGT1A5	8.08e-05	25	48	3	M605
Pathway	WP_GLUCURONIDATION	UGT1A4 UGT1A3 UGT1A5	9.12e-05	26	48	3	M39404
Pathway	KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	UGT1A4 UGT1A3 UGT1A5	1.14e-04	28	48	3	M19580
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	UGT1A4 UGT1A3 UGT1A5	1.71e-04	32	48	3	MM14719
Pathway	KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM	UGT1A4 UGT1A3 UGT1A5	3.61e-04	41	48	3	M7399
Pathway	REACTOME_ASPIRIN_ADME	UGT1A4 UGT1A3 UGT1A5	4.45e-04	44	48	3	M45014
Pathway	REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS	UGT1A4 UGT1A3 TPST1 UGT1A5	4.72e-04	107	48	4	MM14595
Pathway	REACTOME_ASPIRIN_ADME	UGT1A4 UGT1A3 UGT1A5	4.76e-04	45	48	3	MM15694
Pathway	REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS	UGT1A4 UGT1A3 TPST1 UGT1A5	5.06e-04	109	48	4	M18788
Pathway	KEGG_DRUG_METABOLISM_OTHER_ENZYMES	UGT1A4 UGT1A3 UGT1A5	6.88e-04	51	48	3	M17726
Pathway	KEGG_STARCH_AND_SUCROSE_METABOLISM	UGT1A4 UGT1A3 UGT1A5	7.28e-04	52	48	3	M14171
Pathway	REACTOME_BIOLOGICAL_OXIDATIONS	UGT1A4 UGT1A3 TPST1 UGT1A5 CYP21A2	8.60e-04	219	48	5	MM14838
Pathway	REACTOME_BIOLOGICAL_OXIDATIONS	UGT1A4 UGT1A3 TPST1 UGT1A5 CYP21A2	8.77e-04	220	48	5	M10320
Pathway	KEGG_RETINOL_METABOLISM	UGT1A4 UGT1A3 UGT1A5	1.33e-03	64	48	3	M9488
Pubmed	A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.	UGT1A4 UGT1A3 UGT1A5	3.87e-07	9	59	3	22511988
Pubmed	A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.	UGT1A4 UGT1A3 UGT1A5	3.87e-07	9	59	3	1339448
Pubmed	Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.	UGT1A4 UGT1A3 UGT1A5	5.52e-07	10	59	3	23642732
Pubmed	UDP-glucuronosyltransferases.	UGT1A4 UGT1A3 UGT1A5	5.52e-07	10	59	3	11465080
Pubmed	A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.	UGT1A4 UGT1A3 UGT1A5	5.52e-07	10	59	3	23371916
Pubmed	A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.	UGT1A4 UGT1A3 UGT1A5	5.52e-07	10	59	3	22558097
Pubmed	Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.	UGT1A4 UGT1A3 UGT1A5	1.01e-06	12	59	3	19419973
Pubmed	Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.	UGT1A4 UGT1A3 UGT1A5	1.01e-06	12	59	3	11434514
Pubmed	UGT1A1 is a major locus influencing bilirubin levels in African Americans.	UGT1A4 UGT1A3 UGT1A5	1.31e-06	13	59	3	22085899
Pubmed	Genome-wide analysis of hepatic lipid content in extreme obesity.	UGT1A4 UGT1A3 UGT1A5	1.31e-06	13	59	3	25246029
Pubmed	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	UGT1A4 UGT1A3 UGT1A5	1.67e-06	14	59	3	21646302
Pubmed	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.	UGT1A4 UGT1A3 UGT1A5	1.67e-06	14	59	3	10836148
Pubmed	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	UGT1A4 UGT1A3 UGT1A5	1.67e-06	14	59	3	14672974
Pubmed	The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.	UGT1A4 UGT1A3 UGT1A5	1.67e-06	14	59	3	9295054
Pubmed	Genome-wide association meta-analysis for total serum bilirubin levels.	UGT1A4 UGT1A3 UGT1A5	2.56e-06	16	59	3	19414484
Pubmed	Cloning, characterization, and expression analysis of the novel acetyltransferase retrogene Ard1b in the mouse.	NAA11 NAA10	2.83e-06	2	59	2	19246321
Pubmed	Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.	UGT1A3 UGT1A5	2.83e-06	2	59	2	8068691
Pubmed	Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.	UGT1A4 UGT1A3	2.83e-06	2	59	2	24641623
Pubmed	The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer.	ESR1 DEK	2.83e-06	2	59	2	23071688
Pubmed	N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.	UGT1A4 UGT1A3	2.83e-06	2	59	2	14570768
Pubmed	Genome-wide association of serum bilirubin levels in Korean population.	UGT1A4 UGT1A3 UGT1A5	3.10e-06	17	59	3	20639394
Pubmed	A genome-wide assessment of variability in human serum metabolism.	UGT1A4 UGT1A3 UGT1A5	4.41e-06	19	59	3	23281178
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	UGT1A4 UGT1A3 UGT1A5 UGT8	4.98e-06	66	59	4	19898482
Pubmed	17β-estradiol enhances α(5) integrin subunit gene expression through ERα-Sp1 interaction and reduces cell motility and invasion of ERα-positive breast cancer cells.	ESR1 ITGA5	8.48e-06	3	59	2	20052536
Pubmed	Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway.	NAA11 NAA10	8.48e-06	3	59	2	34355692
Pubmed	The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn.	GRIA3 LYN	8.48e-06	3	59	2	9892356
Pubmed	Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.	UGT1A3 UGT1A5	8.48e-06	3	59	2	12051676
Pubmed	Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4.	UGT1A4 UGT1A3	8.48e-06	3	59	2	23611809
Pubmed	A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.	UGT1A3 UGT1A5	8.48e-06	3	59	2	21383159
Pubmed	Genetic determinants influencing human serum metabolome among African Americans.	UGT1A4 UGT1A3 UGT1A5	9.15e-06	24	59	3	24625756
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EP400 BTBD7 NPRL3 NAV2 LRP4 HUWE1 MLXIP ITGA5 TTC3 ADCY9	1.54e-05	1105	59	10	35748872
Pubmed	Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.	UGT1A4 UGT1A5	1.69e-05	4	59	2	18223459
Pubmed	Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.	UGT1A3 UGT1A5	1.69e-05	4	59	2	12644700
Pubmed	Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.	UGT1A4 UGT1A3	1.69e-05	4	59	2	9535849
Pubmed	Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue.	UGT1A4 UGT1A3	1.69e-05	4	59	2	9271343
Pubmed	Interference between proteins Hap46 and Hop/p60, which bind to different domains of the molecular chaperone hsp70/hsc70.	ESR1 STIP1	1.69e-05	4	59	2	9774640
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	TPST1 CHST4 NAA10 UGT8 NDUFV2	1.96e-05	193	59	5	19343046
Pubmed	Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program.	ESR1 KDM2A	2.82e-05	5	59	2	30118678
Pubmed	Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations.	UGT1A3 UGT1A5	2.82e-05	5	59	2	7677729
Pubmed	A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).	NAA11 NAA10	2.82e-05	5	59	2	19480662
Pubmed	Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.	NAA11 NAA10	2.82e-05	5	59	2	16638120
Pubmed	Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.	UGT1A4 UGT1A3	2.82e-05	5	59	2	15057901
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	LRP4 RYR3	4.23e-05	6	59	2	26025922
Pubmed	Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.	UGT1A4 UGT1A3	4.23e-05	6	59	2	19204906
Pubmed	A novel estrogen receptor alpha-associated protein, template-activating factor Ibeta, inhibits acetylation and transactivation.	ESR1 TAF1B	4.23e-05	6	59	2	12511607
Pubmed	Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.	UGT1A4 UGT1A5	5.91e-05	7	59	2	8467709
Pubmed	Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).	UGT1A3 UGT1A5	5.91e-05	7	59	2	8464825
Pubmed	Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.	UGT1A4 UGT1A3	7.87e-05	8	59	2	17179145
Pubmed	Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.	UGT1A4 UGT1A3	7.87e-05	8	59	2	20610558
Pubmed	Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism.	UGT1A4 UGT1A3	7.87e-05	8	59	2	12695355
Pubmed	Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.	UGT1A4 UGT1A3	7.87e-05	8	59	2	22579593
Pubmed	Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.	MYH1 ESR1 RYR3	8.59e-05	50	59	3	27597886
Pubmed	Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.	ESR1 LRP4	1.26e-04	10	59	2	20554715
Pubmed	Human metabolic individuality in biomedical and pharmaceutical research.	UGT1A4 UGT1A3 UGT1A5	1.27e-04	57	59	3	21886157
Pubmed	Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.	SIM2 TTC3	1.54e-04	11	59	2	9503011
Pubmed	The protein interaction landscape of the human CMGC kinase group.	EP400 CLK3 TAF1B MED31 STIP1 ZNF510 HUWE1	1.71e-04	695	59	7	23602568
Pubmed	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.	UGT1A4 UGT1A3	1.85e-04	12	59	2	20308471
Pubmed	A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates.	NAA11 NAA10	1.85e-04	12	59	2	19660095
Pubmed	Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.	UGT1A4 UGT1A3	1.85e-04	12	59	2	18161889
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	GRIA3 KDM2A HUWE1	2.24e-04	69	59	3	32238831
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	EP400 COPG1 CTR9 STIP1 HUWE1	2.52e-04	332	59	5	32786267
Pubmed	Mapping genes that control hormone-induced ovulation rate in mice.	ESR1 CYP21A2	2.54e-04	14	59	2	10491617
Pubmed	New sequence variants associated with bone mineral density.	ESR1 LRP4	2.54e-04	14	59	2	19079262
Pubmed	Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters.	MYH1 LRP4	2.54e-04	14	59	2	29323161
Pubmed	Physical and comparative mapping of distal mouse chromosome 16. 5 p5.	SIM2 TTC3	3.34e-04	16	59	2	9750193
Pubmed	Discovery and refinement of loci associated with lipid levels.	UGT1A4 UGT1A3 UGT1A5 LRP4	4.62e-04	211	59	4	24097068
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	EP400 COPG1 MYO9A HUWE1	4.62e-04	211	59	4	17314511
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZFYVE9 CTR9 KDM2A ZNF510 HUWE1 TTC3	4.93e-04	591	59	6	15231748
Pubmed	Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.	COPG1 STIP1 HUWE1 DEK	5.78e-04	224	59	4	32941674
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	EP400 COPG1 KDM2A HUWE1 SIM2 DEK NDUFV2	6.03e-04	857	59	7	25609649
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ESR1 ITGA5	7.00e-04	23	59	2	23152823
Pubmed	Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.	EP400 HUWE1	7.00e-04	23	59	2	22038470
Pubmed	An unappreciated role for RNA surveillance.	ZFYVE9 CLK3 IL17RB	7.07e-04	102	59	3	14759258
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	COPG1 CTR9 STIP1 HUWE1 LYN	7.51e-04	422	59	5	27342126
Pubmed	P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.	EP400 HUWE1	8.28e-04	25	59	2	36708875
Pubmed	Congenital Myasthenic Syndromes Overview	MYO9A LRP4	8.96e-04	26	59	2	20301347
Pubmed	Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.	NAV2 MLXIP	9.66e-04	27	59	2	19026994
Pubmed	Use of comparative physical and sequence mapping to annotate mouse chromosome 16 and human chromosome 21.	SIM2 TTC3	1.19e-03	30	59	2	11374901
Pubmed	GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles.	TPST1 COPG1	1.36e-03	32	59	2	34473204
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	EP400 CTR9 LRP4	1.42e-03	130	59	3	12421765
Pubmed	The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.	NPRL3 VPS16	1.44e-03	33	59	2	33452816
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	CTR9 HUWE1	1.44e-03	33	59	2	33567268
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYH1 SAMD9L COPG1 STIP1 HUWE1 LYN	1.53e-03	736	59	6	29676528
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	EP400 COPG1 CTR9 NAA10 STIP1 HUWE1 LYN DEK	1.66e-03	1318	59	8	30463901
Cytoband	2q37	UGT1A4 UGT1A3 UGT1A5	8.83e-06	31	59	3	2q37
Cytoband	8q13	PDE7A LYN	1.06e-04	12	59	2	8q13
Cytoband	14q32.12	BTBD7 UNC79	6.45e-04	29	59	2	14q32.12
Cytoband	Ensembl 112 genes in cytogenetic band chr11p11	LRP4 OR4C13 OR4X1	1.03e-03	153	59	3	chr11p11
Cytoband	11p11.12	OR4A5 OR4C13	1.35e-03	42	59	2	11p11.12
Cytoband	Ensembl 112 genes in cytogenetic band chr2q37	UGT1A4 UGT1A3 UGT1A5	3.12e-03	226	59	3	chr2q37
Cytoband	11p11.2	LRP4 OR4X1	5.17e-03	83	59	2	11p11.2
GeneFamily	UDP glucuronosyltransferases	UGT1A4 UGT1A3 UGT1A5 UGT8	1.37e-06	32	47	4	363
GeneFamily	N(alpha)-acetyltransferase subunits\|GCN5 related N-acetyltransferases	NAA11 NAA10	4.29e-04	12	47	2	660
GeneFamily	GCN5 related N-acetyltransferases	NAA11 NAA10	1.76e-03	24	47	2	1134
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	CTR9 STIP1 TTC3	3.32e-03	115	47	3	769
GeneFamily	Sulfotransferases, membrane bound	TPST1 CHST4	4.16e-03	37	47	2	763
GeneFamily	Olfactory receptors, family 4	OR4A5 OR4C13 OR4X1	4.58e-03	129	47	3	151
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TPST1 MYO9A NAV2 UGT8 SIM2	4.87e-06	190	58	5	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TPST1 MYO9A NAV2 UGT8 SIM2	4.87e-06	190	58	5	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPST1 MYO9A NAV2 UGT8 SIM2	4.99e-06	191	58	5	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TPST1 MYO9A NAV2 UGT8 SIM2	4.99e-06	191	58	5	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	TPST1 MYO9A NAV2 UGT8 SIM2	5.66e-06	196	58	5	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
Drug	2,4,6-TCB	UGT1A4 UGT1A3 ESR1 UGT1A5	1.98e-08	12	59	4	CID000037247
Drug	5 alpha-androstane-3 beta,17 beta-diol	UGT1A4 UGT1A3 ESR1 UGT1A5 CYP21A2 STIP1 HUWE1	4.98e-07	185	59	7	CID000011301
Drug	AC1L1FK5	UGT1A4 UGT1A3 ESR1 UGT1A5 CYP21A2 UGT8	1.04e-06	129	59	6	CID000003272
Drug	PCB 156	UGT1A4 UGT1A3 ESR1 UGT1A5	1.21e-06	31	59	4	CID000038019
Drug	AC1MRQNQ	UGT1A4 UGT1A3 UGT1A5	1.37e-06	9	59	3	CID003522271
Drug	DHPASiU	UGT1A4 UGT1A3 UGT1A5	1.37e-06	9	59	3	CID000197602
Drug	Chebi:32663	UGT1A4 UGT1A3 UGT1A5	1.37e-06	9	59	3	CID005460873
Drug	3-iodophenol	UGT1A4 UGT1A3 UGT1A5	1.37e-06	9	59	3	CID000012272
Drug	AC1L4J7U	UGT1A4 UGT1A3 UGT1A5	1.37e-06	9	59	3	CID000186631
Drug	AC1Q6OQG	UGT1A4 UGT1A3 ESR1 UGT1A5	1.57e-06	33	59	4	CID000009686
Drug	N-Fg	UGT1A4 UGT1A3 UGT1A5 UGT8	2.52e-06	37	59	4	CID000445227
Drug	3 -hydroxypregn-5-en-20-one	UGT1A4 UGT1A3 CYP4Z1 ESR1 UGT1A5 CYP21A2 ADCY9	2.68e-06	238	59	7	CID000001027
Drug	4-nitrophenyl)imidazole	UGT1A4 UGT1A3 UGT1A5	2.69e-06	11	59	3	CID000123155
Drug	AC1O5XMV	UGT1A4 UGT1A3 UGT1A5	2.69e-06	11	59	3	CID006442661
Drug	diosmetin	UGT1A4 UGT1A3 CYP4Z1 UGT1A5 CYP21A2	2.75e-06	85	59	5	CID005281612
Drug	x Me	UGT1A4 UGT1A3 UGT1A5 SIM2	2.81e-06	38	59	4	CID009600424
Drug	dioxin	UGT1A4 UGT1A3 CYP4Z1 ESR1 UGT1A5 CYP21A2 SIM2 ITGA5	3.03e-06	347	59	8	CID000015625
Drug	N-OH-DABZ	UGT1A4 UGT1A3 UGT1A5	3.58e-06	12	59	3	CID000051366
Drug	1-O-beta-D-glucopyranosyl-D-mannitol	UGT1A4 UGT1A3 UGT1A5	3.58e-06	12	59	3	CID000088735
Drug	7,7,7-triphenylheptanoic acid	UGT1A4 UGT1A3 UGT1A5	3.58e-06	12	59	3	CID000276709
Drug	nonanoyl-N-methylglucamide	UGT1A4 UGT1A3 UGT1A5	3.58e-06	12	59	3	CID000160090
Drug	PTBP	UGT1A4 UGT1A3 ESR1 UGT1A5	4.23e-06	42	59	4	CID000007393
Drug	tritanol	UGT1A4 UGT1A3 UGT1A5	4.64e-06	13	59	3	CID000006457
Drug	5-azido-UDP-glucuronic acid	UGT1A4 UGT1A3 UGT1A5	4.64e-06	13	59	3	CID003081279
Drug	cotinine-N-glucuronide	UGT1A4 UGT1A3 UGT1A5	4.64e-06	13	59	3	CID000000411
Drug	anthraflavic acid	UGT1A4 UGT1A3 ESR1 UGT1A5	5.11e-06	44	59	4	CID000006776
Drug	DB04103	UGT1A4 UGT1A3 ESR1 UGT1A5 NPRL3	5.28e-06	97	59	5	CID004469987
Drug	propranolol glucuronide	UGT1A4 UGT1A3 UGT1A5	5.90e-06	14	59	3	CID000119515
Drug	PCB-61	UGT1A4 UGT1A3 UGT1A5	5.90e-06	14	59	3	CID000036401
Drug	afloqualone	UGT1A4 UGT1A3	6.60e-06	2	59	2	ctd:C033541
Drug	2,2',3,5,5'-pentachlorobiphenyl	UGT1A4 UGT1A3 UGT1A5	7.36e-06	15	59	3	CID000040469
Drug	coumarin-3-carboxylic acid	UGT1A4 UGT1A3 UGT1A5	7.36e-06	15	59	3	CID000010752
Drug	sulforaphane nitrile	UGT1A4 UGT1A3 UGT1A5	7.36e-06	15	59	3	CID000543743
Drug	afloqualone	UGT1A4 UGT1A3 UGT1A5	7.36e-06	15	59	3	CID000002040
Drug	naphthyl sulphate	UGT1A4 UGT1A3 UGT1A5	7.36e-06	15	59	3	CID000114775
Drug	EM-652	UGT1A4 UGT1A3 ESR1 UGT1A5	7.90e-06	49	59	4	CID000155435
Drug	p,p'-hydroxy-DDT	UGT1A4 UGT1A3 ESR1 UGT1A5	8.57e-06	50	59	4	CID000076302
Drug	quercetin-3,4'-diglucoside	UGT1A4 UGT1A3 UGT1A5	9.04e-06	16	59	3	CID005320835
Drug	1'-hydroxyestragole	UGT1A4 UGT1A3 UGT1A5	9.04e-06	16	59	3	CID000040003
Drug	bilirubin-phosphate	UGT1A4 UGT1A3 UGT1A5	9.04e-06	16	59	3	CID005497144
Drug	(+/-)-Abacavir	UGT1A4 UGT1A3 UGT1A5 CYP21A2	9.28e-06	51	59	4	CID000001971
Drug	8-prenylnaringenin	UGT1A4 UGT1A3 ESR1 UGT1A5	1.00e-05	52	59	4	CID000480764
Drug	triclocarban	UGT1A4 UGT1A3 ESR1	1.10e-05	17	59	3	ctd:C009540
Drug	3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one	UGT1A4 UGT1A3 UGT1A5	1.10e-05	17	59	3	CID000003573
Drug	6-hydroxychrysene	UGT1A4 UGT1A3 UGT1A5	1.10e-05	17	59	3	CID000037766
Drug	Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A	NPRL3 STIP1 ZNF510 ADCY9 IL17RB OR1D2	1.13e-05	195	59	6	3663_DN
Drug	AC1Q6OQF	UGT1A4 UGT1A3 ESR1 UGT1A5	1.26e-05	55	59	4	CID000009685
Drug	ethyl-beta-D-6-glucosiduronic acid	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID000152226
Drug	Br 2	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID003060900
Drug	SureCN12722713	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID005488034
Drug	2,3,7-trichlorodibenzo-p-dioxin	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID000036614
Drug	ApApG	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID003081975
Drug	C1 11-32	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID000443077
Drug	C11131	UGT1A4 UGT1A3 UGT1A5	1.31e-05	18	59	3	CID000443076
Drug	AC1Q7AUJ	UGT1A4 UGT1A3 CYP4Z1 UGT1A5 CYP21A2	1.32e-05	117	59	5	CID000003303
Drug	rifampicin	UGT1A4 UGT1A3 CYP4Z1 ESR1 UGT1A5 CYP21A2 NPRL3	1.39e-05	306	59	7	CID005381226
Drug	benzphetamine	UGT1A4 UGT1A3 UGT1A5 CYP21A2 KDM2A	1.43e-05	119	59	5	CID000002341
Drug	cis isomer	UGT1A4 UGT1A3 ESR1 UGT1A5	1.55e-05	58	59	4	CID006474725
Drug	almokalant	UGT1A4 UGT1A3 UGT1A5	1.56e-05	19	59	3	CID003033962
Drug	9-OH-risperidone	UGT1A4 UGT1A3 UGT1A5	1.56e-05	19	59	3	CID000475100
Drug	5alpha-spirostan-3beta-ol	UGT1A4 UGT1A3 UGT1A5	1.56e-05	19	59	3	CID000091433
Drug	4-hydroxybiphenyl	UGT1A4 UGT1A3 ESR1 UGT1A5	1.66e-05	59	59	4	CID000007103
Drug	4-hydroxyestrone	UGT1A4 UGT1A3 ESR1 UGT1A5	1.66e-05	59	59	4	CID000018418
Drug	PhIP-HCl	UGT1A4 UGT1A3 CYP4Z1 ESR1 UGT1A5	1.68e-05	123	59	5	CID000001530
Drug	UDP-alpha-d-xylopyranose	UGT1A4 UGT1A3 UGT1A5 UGT8	1.78e-05	60	59	4	CID000001165
Drug	tectochrysin	UGT1A4 UGT1A3 UGT1A5	1.83e-05	20	59	3	CID005281954
Drug	AC1L1OBF	UGT1A4 UGT1A3 UGT1A5	1.83e-05	20	59	3	CID000032736
Drug	4'-hydroxydiclofenac	UGT1A4 UGT1A3 UGT1A5	1.83e-05	20	59	3	CID000116545
Drug	hexobarbital	UGT1A4 UGT1A3 CYP4Z1 UGT1A5 CYP21A2	1.96e-05	127	59	5	CID000003608
Drug	estriol-16-glucuronide	UGT1A4 UGT1A3 UGT1A5	2.13e-05	21	59	3	CID000122281
Drug	dulcin	UGT1A4 UGT1A3 UGT1A5	2.13e-05	21	59	3	CID000009013
Drug	Benzamidoxime hydrochloride	UGT1A4 UGT1A3 UGT1A5	2.13e-05	21	59	3	CID000069186
Drug	2-hydroxyestradiol	UGT1A4 UGT1A3 ESR1 UGT1A5	2.16e-05	63	59	4	CID000009684
Drug	amifostine	CHST4 NPRL3 UGT8 ADCY9	2.45e-05	65	59	4	CID000002141
Drug	amonafide	UGT1A4 UGT1A3 UGT1A5	2.46e-05	22	59	3	CID000050515
Drug	N-methylpiperazine	UGT1A4 UGT1A3 UGT1A5	2.46e-05	22	59	3	CID000053167
Drug	trans-3,4,5-trihydroxystilbene	UGT1A4 UGT1A3 ESR1 UGT1A5 CYP21A2 GRIA3 ITGA5 LYN DEK	2.49e-05	608	59	9	CID000005056
Drug	ethoxytriethyleneglycol	UGT1A4 UGT1A3 UGT1A5 GRIA3	2.60e-05	66	59	4	CID000008190
Drug	amidoxime	UGT1A4 UGT1A3 UGT1A5	2.82e-05	23	59	3	CID000465967
Drug	estradiol-3-glucuronide	UGT1A4 UGT1A3 UGT1A5	2.82e-05	23	59	3	CID000066651
Drug	phenanthridine	UGT1A4 UGT1A3 UGT1A5	2.82e-05	23	59	3	CID000009189
Drug	AS-3201	UGT1A4 UGT1A3 UGT1A5	3.22e-05	24	59	3	CID000153948
Drug	5-MOP	UGT1A4 UGT1A3 UGT1A5	3.65e-05	25	59	3	CID000002355
Drug	AzMC	UGT1A4 UGT1A3 UGT1A5	3.65e-05	25	59	3	CID000064986
Drug	N-acetylbenzidine	UGT1A4 UGT1A3 UGT1A5	3.65e-05	25	59	3	CID000018787
Drug	5,6-benzoquinoline	UGT1A4 UGT1A3 UGT1A5	3.65e-05	25	59	3	CID000006796
Drug	N-phenylmaleimide	UGT1A4 UGT1A3 UGT1A5	3.65e-05	25	59	3	CID000013662
Drug	benzo(a)pyrene	UGT1A4 UGT1A3 CYP4Z1 ESR1 UGT1A5 CYP21A2 UGT8	3.79e-05	358	59	7	CID000002336
Drug	2,2,2-trichloroethanol	UGT1A4 UGT1A3 CYP4Z1 UGT1A5	3.87e-05	73	59	4	CID000008259
Drug	DiMeIQx	UGT1A4 UGT1A3 UGT1A5	4.63e-05	27	59	3	CID000104739
Drug	diflunisal	UGT1A4 UGT1A3 UGT1A5	4.63e-05	27	59	3	CID000003059
Drug	mepyramine	UGT1A4 UGT1A3 UGT1A5 CYP21A2 ADCY9	4.95e-05	154	59	5	CID000004992
Drug	AC1N8H7N	UGT1A4 UGT1A3 UGT1A5 NPRL3	5.03e-05	78	59	4	CID004318740
Drug	N-hydroxy-4-aminobiphenyl	UGT1A4 UGT1A3 UGT1A5	5.17e-05	28	59	3	CID000081261
Drug	CARMINE	UGT1A4 UGT1A3 UGT1A5	5.17e-05	28	59	3	CID000014749
Drug	erucin	UGT1A4 UGT1A3 UGT1A5	5.17e-05	28	59	3	CID000078160
Drug	H-Ni	UGT1A4 UGT1A3 UGT1A5	5.17e-05	28	59	3	CID000445665
Drug	4-hydroxyestradiol	UGT1A4 UGT1A3 ESR1 UGT1A5	5.29e-05	79	59	4	CID000001743
Drug	catechol	UGT1A4 UGT1A3 ESR1 UGT1A5 ARHGEF25 ADCY9	5.33e-05	257	59	6	CID000000289
Drug	AC1L1JAL	UGT1A4 UGT1A3 UGT1A5	5.76e-05	29	59	3	CID000004954
Disease	X-11793--oxidized bilirubin measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0021260
Disease	Succinimide measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0022118
Disease	X-11530 measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0021249
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0800696
Disease	X-10458 measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0800692
Disease	X-24849 measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0800909
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0802740
Disease	X-16946 measurement	UGT1A4 UGT1A3 UGT1A5	4.22e-07	8	59	3	EFO_0800766
Disease	X-11442 measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0021236
Disease	X-11441 measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0801037
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0802127
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0801036
Disease	X-11880 measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0800698
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0004570, GO_0009410
Disease	protein-tyrosine kinase 6 measurement	UGT1A4 UGT1A3 UGT1A5	6.32e-07	9	59	3	EFO_0020691
Disease	X-21448 measurement	UGT1A4 UGT1A3 UGT1A5	9.02e-07	10	59	3	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A4 UGT1A3 UGT1A5	9.02e-07	10	59	3	EFO_0802185
Disease	X-23974 measurement	UGT1A4 UGT1A3 UGT1A5	9.02e-07	10	59	3	EFO_0800867
Disease	bilirubin measurement, response to tenofovir	UGT1A4 UGT1A3 UGT1A5	9.02e-07	10	59	3	EFO_0004570, EFO_0009279
Disease	X-21796 measurement	UGT1A4 UGT1A3 UGT1A5	1.24e-06	11	59	3	EFO_0800825
Disease	insomnia, bilirubin measurement	UGT1A4 UGT1A3 UGT1A5	1.24e-06	11	59	3	EFO_0004570, EFO_0004698
Disease	histidine betaine (hercynine) measurement	UGT1A4 UGT1A3 UGT1A5	1.24e-06	11	59	3	EFO_0800972
Disease	aldosterone measurement	UGT1A4 UGT1A3 UGT1A5	1.24e-06	11	59	3	EFO_0010219
Disease	biliverdin measurement	UGT1A4 UGT1A3 UGT1A5	1.65e-06	12	59	3	EFO_0021033
Disease	p-cresol glucuronide measurement	UGT1A4 UGT1A3 UGT1A5	1.65e-06	12	59	3	EFO_0800079
Disease	retinol dehydrogenase 16 measurement	UGT1A4 UGT1A3 UGT1A5	2.14e-06	13	59	3	EFO_0802007
Disease	Ogden syndrome (implicated_via_orthology)	NAA11 NAA10	3.93e-06	2	59	2	DOID:0050781 (implicated_via_orthology)
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A4 UGT1A3 UGT1A5	5.06e-06	17	59	3	EFO_0004611, EFO_0007800
Disease	urate measurement, spine bone mineral density	UGT1A4 UGT1A3 UGT1A5 NAV2	5.64e-06	58	59	4	EFO_0004531, EFO_0007701
Disease	angiopoietin-related protein 1 measurement	UGT1A4 UGT1A3 UGT1A5	6.07e-06	18	59	3	EFO_0801382
Disease	tissue factor measurement	UGT1A4 UGT1A3 UGT1A5	9.84e-06	21	59	3	EFO_0010623
Disease	lean body mass	COPG1 ESR1 CYP21A2 NPRL3 KDM2A GPR139 ADCY9	1.05e-05	379	59	7	EFO_0004995
Disease	xanthurenate measurement	UGT1A4 UGT1A3 UGT1A5	2.67e-05	29	59	3	EFO_0010551
Disease	cholelithiasis	UGT1A4 UGT1A3 UGT1A5 CYP21A2	2.97e-05	88	59	4	EFO_0004799
Disease	response to dolutegravir	UGT1A4 UGT1A3 UGT1A5	2.97e-05	30	59	3	EFO_0600017
Disease	body weight	COPG1 ESR1 CYP21A2 NPRL3 UGT8 KDM2A HUWE1 CAPZA3 UNC79 GPR139 ADCY9	3.52e-05	1261	59	11	EFO_0004338
Disease	body surface area	COPG1 ESR1 CYP21A2 NPRL3 KDM2A UNC79 GPR139 ADCY9	4.06e-05	643	59	8	EFO_0022196
Disease	gallstones	UGT1A4 UGT1A3 UGT1A5 CYP21A2	6.62e-05	108	59	4	EFO_0004210
Disease	pregnenetriol sulfate measurement	UGT1A4 UGT1A5	2.14e-04	11	59	2	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A4 UGT1A5	2.14e-04	11	59	2	EFO_0600039
Disease	pregnenetriol disulfate measurement	UGT1A4 UGT1A5	3.02e-04	13	59	2	EFO_0800587
Disease	X-21441 measurement	UGT1A4 UGT1A5	5.24e-04	17	59	2	EFO_0800814
Disease	thyroxine measurement	UGT1A4 UGT1A3 UGT1A5	6.23e-04	83	59	3	EFO_0005130
Disease	hormone measurement	UGT1A4 UGT1A3 UGT1A5	6.45e-04	84	59	3	EFO_0004730
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A LRP4	6.58e-04	19	59	2	C0751884
Disease	cerebellar cortex volume measurement	CYP21A2 SIM2	8.05e-04	21	59	2	EFO_0010291
Disease	free androgen index	UGT1A4 ESR1 UGT1A5 CYP21A2 GPR139	9.10e-04	374	59	5	EFO_0007005
Disease	mean reticulocyte volume	EP400 NPRL3 ZNF510 ENPP4 MLXIP LYN ADCY9	1.04e-03	799	59	7	EFO_0010701
Disease	mean arterial pressure, unipolar depression	CHODL NPRL3	1.88e-03	32	59	2	EFO_0003761, EFO_0006340
Disease	bilirubin measurement	UGT1A4 UGT1A3 UGT1A5 CYP21A2 MLXIP	1.90e-03	442	59	5	EFO_0004570
Disease	urate measurement	MYO9A CYP21A2 LRP4 STIP1 MLXIP OR4X1 ARHGEF25	2.00e-03	895	59	7	EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
YKKCMLVHYEQLVLH	TPST1	231	O60507
VKNMLYPLALSYICH	UGT1A3	211	P35503
KLYVNDHYPKGNCNM	CAPZA3	126	Q96KX2
KQCLDYHYQEMQALK	EP400	366	Q96L91
LHMYVVYCQNKPKSE	ARHGEF25	246	Q86VW2
YVKENCKPLKSYMLQ	CLK3	571	P49761
CMLYLKYPKNIVENH	RAD51AP2	611	Q09MP3
KQLHPYLKQMCYGNL	RAD51AP2	1141	Q09MP3
DLKQKYQKLILMYHP	DNAJC24	26	Q6P3W2
CKLYSQQLMRQYHKE	CFAP65	1521	Q6ZU64
YLKYPQCLHMLELLQ	MED31	66	Q9Y3C7
DYNALSVCPKYHLMK	IL17RB	456	Q9NRM6
IKDDNLMPAYYKCIQ	CYP21A2	181	P08686
LMPAYYKCIQEVLKT	CYP21A2	186	P08686
LESPYVMYKKNHEQL	GRIA3	431	P42263
YSMKCKNVVPLYDLL	ESR1	526	P03372
YVAICKPLHYMAIMN	OR4X1	121	Q8NH49
TQAMHCYLKEPKLAN	PDE7A	221	Q13946
HCNLLCLPENYQMKY	NAA10	16	P41227
YNKLKNCSPHMNVYL	ENPP4	281	Q9Y6X5
KAIIIYPLCENNVYM	NPRL3	321	Q12980
YHIFYQIMSNKKPDL	MYH1	286	P12882
YVAICKPLHYTTVMK	OR4C13	121	Q8NGP0
RKYPYHLMLQKFLCS	HUWE1	1146	Q7Z6Z7
QCEAVYKALKMPYRI	ITGA5	956	P08648
YMQYLEKRKNPVCHF	MLXIP	171	Q9HAP2
NAILEMQYPKVQKYC	KDM2A	186	Q9Y2K7
NVYCIHVDEKAPMKY	GCNT7	136	Q6ZNI0
VTMKQICKKVYENYP	DEK	341	P35659
KYNLLPEKSMYDLVH	UGT8	221	Q16880
VQMYENCLRKFYKHQ	CTR9	701	Q6PD62
QMKTYLYPKCTDHRV	ADCY9	1236	O60503
PKKYATVILHCMYTD	BTBD7	321	Q9P203
CYRYHVIAIKMKQPC	MARCHF11	216	A6NNE9
FPCISDMIKHYQKQA	LYN	201	P07948
LCQKYPRKHAVLMNF	COPG1	386	Q9Y678
NSHCIKMLVYQYDKN	GPR139	331	Q6DWJ6
CMVYLKPLHTYSVKD	OR1D2	256	P34982
YVAICKPLHYLTIMN	OR4A5	121	Q8NH83
NIDYPHYCDLLRKMN	SPATA48	26	A4D263
YPQAMKHYTEAIKRN	STIP1	376	P31948
PKHSICNDKYFYIQM	SAMD9L	311	Q8IVG5
YLHPNILCMKYLMEV	TAF1B	301	Q53T94
KYHKCPYIIGTMNQA	NAV2	2246	Q8IVL1
KVIHCSGYLKIRQYM	SIM2	181	Q14190
LKKEDQPYYVMQVIC	CHST4	236	Q8NCG5
NMKHNYICKYEPEIN	CHODL	171	Q9H9P2
FEVYHKLMEKYPCAV	CYP4Z1	66	Q86W10
LSYDDPDKKMYHLCI	TTC30B	531	Q8N4P2
HCNLLCLPENYQMKY	NAA11	16	Q9BSU3
LNEYCKMPLKLLTNH	RYR3	2496	Q15413
YLPFVEICMKQHNKY	VPS16	756	Q9H269
VKNMLYPLALSYLCH	UGT1A5	211	P35504
YKYHITKIVMEDCNL	TTC3	201	P53804
LCIYVRHKEYKVMVN	LGALS14	91	Q8TCE9
YNKLNMGIKHYELNP	ZNF510	326	Q9Y2H8
LMKKNYLHNFCSQVP	ZFYVE9	541	O95405
NPVYHCQLLECLMKY	UNC79	236	Q9P2D8
VKNMLYPLALSYICH	UGT1A4	211	P22310
CKDYLIEAMKYHLLP	KLHL2	271	O95198
IPKPAMYNQLCYKKE	LRP4	1781	O75096
NPKYVKMYDNHQLGK	MYO9A	196	B2RTY4
MYNRKPVGKYHIQVC	NDUFV2	121	P19404