Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-cysteine S-stearoyltransferase activity	ZDHHC15 ZDHHC6	1.79e-04	7	59	2	GO:0140439
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA4 PLXNA1	5.56e-04	12	59	2	GO:0017154
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	RLF HIVEP3 ZNF600 ZNF143 ZNF596 ZNF76 ZNF578 NTN1 ZNF83 CASZ1 ZNF518A PRDM1	7.44e-04	1412	59	12	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HIVEP3 ZNF600 ZNF143 ZNF596 ZNF76 ZNF578 NTN1 ZNF83 CREBBP CASZ1 ZNF518A PRDM1	9.92e-04	1459	59	12	GO:0000977
GeneOntologyMolecularFunction	histone methyltransferase binding	PHF1 PRDM1	1.27e-03	18	59	2	GO:1990226
GeneOntologyBiologicalProcess	neuron projection guidance	ABLIM1 BMPR1B PLEKHG4 SLIT3 PLXNA4 NTN1 PLXNA1	1.50e-05	286	58	7	GO:0097485
GeneOntologyCellularComponent	contractile actin filament bundle	SHROOM4 ABLIM1 TRIP6 LPP ABLIM3 ZYX	5.09e-07	107	58	6	GO:0097517
GeneOntologyCellularComponent	stress fiber	SHROOM4 ABLIM1 TRIP6 LPP ABLIM3 ZYX	5.09e-07	107	58	6	GO:0001725
GeneOntologyCellularComponent	actomyosin	SHROOM4 ABLIM1 TRIP6 LPP ABLIM3 ZYX	8.63e-07	117	58	6	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	SHROOM4 ABLIM1 TRIP6 LPP ABLIM3 ZYX	9.07e-07	118	58	6	GO:0032432
GeneOntologyCellularComponent	actin cytoskeleton	SHROOM4 LIMD2 ABLIM1 TRIP6 LPP NTN1 ABLIM3 ZYX	1.80e-04	576	58	8	GO:0015629
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA4 PLXNA1	5.79e-04	13	58	2	GO:0002116
Domain	LIM	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.01e-09	69	59	7	PF00412
Domain	-	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.23e-09	70	59	7	2.10.110.10
Domain	Znf_LIM	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.47e-09	71	59	7	IPR001781
Domain	LIM_DOMAIN_1	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.47e-09	71	59	7	PS00478
Domain	LIM_DOMAIN_2	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.47e-09	71	59	7	PS50023
Domain	LIM	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.47e-09	71	59	7	SM00132
Domain	ZINC_FINGER_C2H2_2	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	9.35e-08	775	59	14	PS50157
Domain	ZINC_FINGER_C2H2_1	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	9.65e-08	777	59	14	PS00028
Domain	Znf_C2H2-like	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	1.30e-07	796	59	14	IPR015880
Domain	Znf_C2H2	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	1.49e-07	805	59	14	IPR007087
Domain	ZnF_C2H2	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	1.56e-07	808	59	14	SM00355
Domain	zf-C2H2	RLF HIVEP3 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	1.89e-07	693	59	13	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 ZNF518A PRDM1	1.42e-06	694	59	12	IPR013087
Domain	-	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 PRDM1	7.71e-06	679	59	11	3.30.160.60
Domain	VWC_out	FRAS1 FCGBP VWF	2.80e-05	19	59	3	SM00215
Domain	AbLIM_anchor	ABLIM1 ABLIM3	5.86e-05	4	59	2	PF16182
Domain	AbLIM_anchor	ABLIM1 ABLIM3	5.86e-05	4	59	2	IPR032402
Domain	YIPPEE	YPEL2 YPEL1	9.75e-05	5	59	2	PS51792
Domain	VWC	FRAS1 FCGBP VWF	2.33e-04	38	59	3	SM00214
Domain	Yippee/Mis18/Cereblon	YPEL2 YPEL1	2.71e-04	8	59	2	IPR004910
Domain	HP	ABLIM1 ABLIM3	2.71e-04	8	59	2	PS51089
Domain	-	ABLIM1 ABLIM3	2.71e-04	8	59	2	1.10.950.10
Domain	Yippee-Mis18	YPEL2 YPEL1	2.71e-04	8	59	2	PF03226
Domain	VHP	ABLIM1 ABLIM3	2.71e-04	8	59	2	PF02209
Domain	Villin_headpiece	ABLIM1 ABLIM3	2.71e-04	8	59	2	IPR003128
Domain	VHP	ABLIM1 ABLIM3	2.71e-04	8	59	2	SM00153
Domain	VWF_dom	FRAS1 FCGBP VWF	3.15e-04	42	59	3	IPR001007
Domain	Plexin_cytopl	PLXNA4 PLXNA1	3.48e-04	9	59	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA4 PLXNA1	3.48e-04	9	59	2	IPR013548
Domain	Plexin	PLXNA4 PLXNA1	3.48e-04	9	59	2	IPR031148
Domain	zf-C2H2_11	ZNF800 ZNF592	3.48e-04	9	59	2	PF16622
Domain	TIL	FCGBP VWF	6.34e-04	12	59	2	PF01826
Domain	C8	FCGBP VWF	6.34e-04	12	59	2	PF08742
Domain	Unchr_dom_Cys-rich	FCGBP VWF	7.48e-04	13	59	2	IPR014853
Domain	C8	FCGBP VWF	7.48e-04	13	59	2	SM00832
Domain	EGF	FRAS1 STAB2 FCGBP SLIT3 ZNF578	8.70e-04	235	59	5	SM00181
Domain	TIL_dom	FCGBP VWF	8.71e-04	14	59	2	IPR002919
Domain	EGF-like_dom	FRAS1 STAB2 FCGBP SLIT3 ADAM29	1.13e-03	249	59	5	IPR000742
Domain	VWD	FCGBP VWF	1.14e-03	16	59	2	SM00216
Domain	VWF_type-D	FCGBP VWF	1.14e-03	16	59	2	IPR001846
Domain	VWFD	FCGBP VWF	1.14e-03	16	59	2	PS51233
Domain	VWD	FCGBP VWF	1.14e-03	16	59	2	PF00094
Domain	LCE	LCE4A LCE2A	1.29e-03	17	59	2	PF14672
Domain	LCE	LCE4A LCE2A	1.29e-03	17	59	2	IPR028205
Domain	CTCK_1	VWF SLIT3	1.45e-03	18	59	2	PS01185
Domain	CT	VWF SLIT3	2.18e-03	22	59	2	SM00041
Domain	zf-DHHC	ZDHHC15 ZDHHC6	2.38e-03	23	59	2	PF01529
Domain	Cys_knot_C	VWF SLIT3	2.81e-03	25	59	2	IPR006207
Domain	DHHC	ZDHHC15 ZDHHC6	2.81e-03	25	59	2	PS50216
Domain	CTCK_2	VWF SLIT3	2.81e-03	25	59	2	PS01225
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC15 ZDHHC6	2.81e-03	25	59	2	IPR001594
Domain	IPT	PLXNA4 PLXNA1	3.27e-03	27	59	2	SM00429
Domain	SPRR/LCE	LCE4A LCE2A	3.52e-03	28	59	2	IPR026075
Domain	VWC	FRAS1 VWF	3.52e-03	28	59	2	PF00093
Domain	EGF_LAM_2	STAB2 NTN1	4.03e-03	30	59	2	PS50027
Domain	EGF_LAM_1	STAB2 NTN1	4.03e-03	30	59	2	PS01248
Domain	TIG	PLXNA4 PLXNA1	4.30e-03	31	59	2	PF01833
Domain	Sema	PLXNA4 PLXNA1	4.30e-03	31	59	2	SM00630
Domain	Semap_dom	PLXNA4 PLXNA1	4.30e-03	31	59	2	IPR001627
Domain	Sema	PLXNA4 PLXNA1	4.30e-03	31	59	2	PF01403
Domain	SEMA	PLXNA4 PLXNA1	4.30e-03	31	59	2	PS51004
Domain	Ig_E-set	TRIM45 PLXNA4 PLXNA1	4.35e-03	104	59	3	IPR014756
Domain	PSI	PLXNA4 PLXNA1	4.58e-03	32	59	2	PF01437
Domain	IPT	PLXNA4 PLXNA1	4.58e-03	32	59	2	IPR002909
Domain	Plexin_repeat	PLXNA4 PLXNA1	4.58e-03	32	59	2	IPR002165
Domain	EGF_Lam	STAB2 NTN1	5.46e-03	35	59	2	SM00180
Domain	VWFC_1	FRAS1 VWF	5.77e-03	36	59	2	PS01208
Pathway	REACTOME_NETRIN_1_SIGNALING	ABLIM1 SLIT3 NTN1 ABLIM3	5.64e-06	44	38	4	M875
Pathway	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	ABLIM1 NTN1 ABLIM3	6.44e-06	14	38	3	M889
Pathway	KEGG_AXON_GUIDANCE	ABLIM1 SLIT3 NTN1 ABLIM3 PLXNA1	2.34e-05	129	38	5	M5539
Pathway	WP_AXON_GUIDANCE	BMPR1B SLIT3 ABLIM3 PLXNA1	4.05e-05	72	38	4	M48335
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 PLXNA1	2.52e-04	9	38	2	MM15030
Pathway	REACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO	SLIT3 NTN1	3.14e-04	10	38	2	M27348
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 PLXNA1	6.31e-04	14	38	2	MM15029
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 PLXNA1	6.31e-04	14	38	2	M7578
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 PLXNA1	7.27e-04	15	38	2	MM15031
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	ABLIM1 SLIT3 PLXNA4 DLG3 NTN1 ABLIM3 PLXNA1	7.59e-04	575	38	7	M29853
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 PLXNA1	8.29e-04	16	38	2	M16498
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 PLXNA1	8.29e-04	16	38	2	M8245
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	ABLIM1 LCE4A KRTAP1-5 SLIT3 PLXNA4 DLG3 NTN1 ABLIM3 CREBBP PLXNA1 LCE2A	1.03e-03	1432	38	11	M509
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXNA4 PLXNA1	1.18e-03	19	38	2	M10959
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	PHF1 HIVEP3 ABLIM1 ZNF143 INTS12 TRIP6 PRICKLE3 ZNF592 ZDHHC6 ZFP64 LPP UNK ZNF76 ZYX PLXNA1 PRDM1	2.69e-13	808	59	16	20412781
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	RLF PHF1 ABLIM1 PRICKLE3 ZDHHC6 ZFP64 RNF145 CREBBP ZYX PLXNA1	2.97e-07	709	59	10	22988430
Pubmed	Functional proteomics mapping of a human signaling pathway.	RLF VWF ZNF592 ZNF76 ZNF83 TNKS2 CREBBP ZYX ZNF518A	6.56e-07	591	59	9	15231748
Pubmed	Loss of migfilin expression has no overt consequences on murine development and homeostasis.	TRIP6 LPP ZYX	1.31e-06	13	59	3	21224394
Pubmed	The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.	TRIP6 LPP ZYX	1.31e-06	13	59	3	22286099
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA4 NTN1 PLXNA1	1.67e-06	14	59	3	20159958
Pubmed	ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf.	ZNF143 ZNF76	2.83e-06	2	59	2	9705341
Pubmed	Transcriptional regulation of the mouse cytosolic chaperonin subunit gene Ccta/t-complex polypeptide 1 by selenocysteine tRNA gene transcription activating factor family zinc finger proteins.	ZNF143 ZNF76	2.83e-06	2	59	2	10893243
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA1	8.48e-06	3	59	2	27397516
Pubmed	The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins.	TRIP6 LPP	8.48e-06	3	59	2	16137684
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA1	8.48e-06	3	59	2	18625214
Pubmed	The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity.	STAB2 VWF	8.48e-06	3	59	2	30124466
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	SLIT3 PLXNA4 PLXNA1	1.47e-05	28	59	3	18617019
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA4 PLXNA1	1.69e-05	4	59	2	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA4 PLXNA1	1.69e-05	4	59	2	25518740
Pubmed	Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.	LPP ZYX	1.69e-05	4	59	2	22665060
Pubmed	Targeting skeletal endothelium to ameliorate bone loss.	HIVEP3 SLIT3	1.69e-05	4	59	2	29785024
Pubmed	Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.	FRAS1 SLIT3	2.82e-05	5	59	2	23536828
Pubmed	Palmitoylation of SARS-CoV-2 Envelope protein is central to virus particle formation.	ZDHHC15 ZDHHC6	2.82e-05	5	59	2	39287388
Pubmed	Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.	YPEL2 YPEL1	2.82e-05	5	59	2	15556292
Pubmed	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.	ABLIM1 ABLIM3	4.23e-05	6	59	2	17194709
Pubmed	LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection.	TRIP6 LPP	4.23e-05	6	59	2	20634563
Pubmed	Slit/Robo-mediated chemorepulsion of vagal sensory axons in the fetal gut.	SLIT3 NTN1	4.23e-05	6	59	2	23161783
Pubmed	Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis.	SLIT3 NTN1	4.23e-05	6	59	2	16439476
Pubmed	miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.	ABLIM1 ABLIM3	5.91e-05	7	59	2	22684256
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA4 PLXNA1	5.91e-05	7	59	2	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA4 PLXNA1	5.91e-05	7	59	2	19655386
Pubmed	Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.	STAB2 VWF	5.91e-05	7	59	2	21029358
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA4 PLXNA1	7.87e-05	8	59	2	15661641
Pubmed	VEGF mediates commissural axon chemoattraction through its receptor Flk1.	VEGFC NTN1	7.87e-05	8	59	2	21658588
Pubmed	PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.	SLIT3 PLXNA1	7.87e-05	8	59	2	25485759
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA4 PLXNA1	7.87e-05	8	59	2	22368082
Pubmed	Genomic response to Wnt signalling is highly context-dependent--evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets.	ABLIM1 SLIT3	7.87e-05	8	59	2	19563800
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXNA4 NTN1 PLXNA1	9.66e-05	52	59	3	26633812
Pubmed	Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion.	SLIT3 NTN1	1.01e-04	9	59	2	25056828
Pubmed	Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway.	SLIT3 NTN1	1.01e-04	9	59	2	22806432
Pubmed	Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.	PLXNA4 PLXNA1	1.01e-04	9	59	2	28751609
Pubmed	Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.	TRIP6 ZYX	1.01e-04	9	59	2	11782456
Pubmed	The role of neuropilins in cell signalling.	PLXNA4 PLXNA1	1.01e-04	9	59	2	19909241
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA4 PLXNA1	1.26e-04	10	59	2	18804103
Pubmed	YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.	YPEL2 YPEL1	1.26e-04	10	59	2	20580816
Pubmed	A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system.	ABLIM1 NTN1	1.26e-04	10	59	2	11163266
Pubmed	CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592.	ZNF592 ZFP64	1.54e-04	11	59	2	20531441
Pubmed	A human MAP kinase interactome.	ABLIM1 ZNF600 VWF ZNF83 CREBBP ZYX	1.74e-04	486	59	6	20936779
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA4 PLXNA1	1.85e-04	12	59	2	25839327
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA4 PLXNA1	1.85e-04	12	59	2	31690636
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA4 PLXNA1	1.85e-04	12	59	2	24179230
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA4 PLXNA1	1.85e-04	12	59	2	23991118
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA4 PLXNA1	1.85e-04	12	59	2	28407732
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA4 PLXNA1	1.85e-04	12	59	2	21270798
Pubmed	Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.	LPP ZYX	1.85e-04	12	59	2	15465019
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA4 PLXNA1	2.18e-04	13	59	2	25959730
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA4 PLXNA1	2.18e-04	13	59	2	10520995
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA4 PLXNA1	2.18e-04	13	59	2	11604131
Pubmed	gdnf activates midline repulsion by Semaphorin3B via NCAM during commissural axon guidance.	NTN1 PLXNA1	2.18e-04	13	59	2	22998873
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA4 PLXNA1	2.18e-04	13	59	2	22723296
Pubmed	β3GnT2 maintains adenylyl cyclase-3 signaling and axon guidance molecule expression in the olfactory epithelium.	PLXNA4 PLXNA1	2.54e-04	14	59	2	21525298
Pubmed	A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system.	SLIT3 NTN1	2.93e-04	15	59	2	25456121
Pubmed	Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.	VEGFC VWF	2.93e-04	15	59	2	28684544
Pubmed	Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.	ABLIM1 BMPR1B PLXNA4	3.10e-04	77	59	3	29445148
Pubmed	Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.	ZDHHC15 ZDHHC6	3.34e-04	16	59	2	23034182
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA4 PLXNA1	3.34e-04	16	59	2	17356169
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	PLXNA4 PLXNA1	3.34e-04	16	59	2	22632726
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA4 PLXNA1	3.34e-04	16	59	2	18489001
Pubmed	Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.	ABLIM1 LPP UNK	3.47e-04	80	59	3	16094384
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA4 PLXNA1	3.79e-04	17	59	2	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA4 PLXNA1	3.79e-04	17	59	2	17626059
Pubmed	Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.	SLIT3 NTN1	3.79e-04	17	59	2	26257608
Pubmed	The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.	SLIT3 NTN1	4.25e-04	18	59	2	16854408
Pubmed	Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.	ABLIM1 DLG3	4.25e-04	18	59	2	19455133
Pubmed	Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.	STAB2 VWF	4.25e-04	18	59	2	21810271
Pubmed	Midline radial glia translocation and corpus callosum formation require FGF signaling.	SLIT3 NTN1	4.25e-04	18	59	2	16715082
Pubmed	Genes, plasticity and mental retardation.	DLG3 CREBBP	4.75e-04	19	59	2	18329113
Pubmed	PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.	VWF PLXNA1	4.75e-04	19	59	2	15239958
Pubmed	Non-cell autonomous control of precerebellar neuron migration by Slit and Robo proteins.	SLIT3 NTN1	4.75e-04	19	59	2	29343636
Pubmed	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.	ABLIM1 DLG3	4.75e-04	19	59	2	15024025
Pubmed	Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons.	SLIT3 NTN1	4.75e-04	19	59	2	23307742
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	ABLIM1 LPP UNK DLG3	5.22e-04	218	59	4	33378226
Pubmed	Genetic dissection of the function of hindbrain axonal commissures.	SLIT3 NTN1	5.27e-04	20	59	2	20231872
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC15 ZDHHC6	5.27e-04	20	59	2	16647879
Pubmed	Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.	SLIT3 NTN1	5.27e-04	20	59	2	20696379
Pubmed	Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function.	BMPR1B VWF	5.82e-04	21	59	2	33372189
Pubmed	Smad4 is required predominantly in the developmental processes dependent on the BMP branch of the TGF-β signaling system in the embryonic mouse retina.	BMPR1B NTN1	5.82e-04	21	59	2	21273545
Pubmed	Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation.	LCE4A LCE2A	6.39e-04	22	59	2	15854049
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FRAS1 SLIT3 PRDM1	6.67e-04	100	59	3	25807483
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	PHF1 ZDHHC15 PRICKLE3 ZNF592 ZDHHC6 ZFP64 CREBBP	6.91e-04	877	59	7	20211142
Pubmed	Differentially expressed late constituents of the epidermal cornified envelope.	LCE4A LCE2A	7.00e-04	23	59	2	11698679
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	PLXNA4 PLXNA1	7.62e-04	24	59	2	15869472
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA4 PLXNA1	7.62e-04	24	59	2	28893946
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RLF HIVEP3 ABLIM1 BMPR1B ZFP64 LPP NTN1 CREBBP CASZ1	8.59e-04	1489	59	9	28611215
Pubmed	Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis.	CASZ1 PRDM1	8.96e-04	26	59	2	32071204
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RLF ABLIM1 ZNF800 ZNF143 PRICKLE3 SLC39A6 CASZ1 ZNF518A	9.28e-04	1203	59	8	29180619
Pubmed	Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube.	SLIT3 PLXNA1	9.66e-04	27	59	2	25843547
Pubmed	BMP receptor 1b is required for axon guidance and cell survival in the developing retina.	BMPR1B NTN1	9.66e-04	27	59	2	12654290
Pubmed	Genetic link between renal birth defects and congenital heart disease.	FRAS1 PRDM1	1.04e-03	28	59	2	27002738
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	SLIT3 PLXNA4 NTN1	1.30e-03	126	59	3	16284245
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ABLIM1 VWF ZNF592 ZNF76 ZNF83 TNKS2 TMEM222 CREBBP	1.41e-03	1285	59	8	35914814
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	PHF1 ABLIM1 VWF ZNF592 TNKS2	1.55e-03	497	59	5	23414517
Pubmed	Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase.	GGN YPEL2	1.62e-03	35	59	2	21779533
Pubmed	Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.	PLXNA4 PLXNA1	1.62e-03	35	59	2	28172500
Interaction	PDLIM7 interactions	PHF1 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	1.17e-05	264	59	7	int:PDLIM7
GeneFamily	LIM domain containing	LIMD2 ABLIM1 TRIP6 PRICKLE3 LPP ABLIM3 ZYX	2.44e-10	59	50	7	1218
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF HIVEP3 ZNF800 ZNF600 ZNF143 ZNF592 ZNF596 ZFP64 ZNF76 ZNF578 ZNF83 CASZ1 ZNF518A PRDM1	5.32e-09	718	50	14	28
GeneFamily	Yippee like family	YPEL2 YPEL1	7.46e-05	5	50	2	1130
GeneFamily	Plexins	PLXNA4 PLXNA1	2.67e-04	9	50	2	683
GeneFamily	Late cornified envelope proteins	LCE4A LCE2A	1.11e-03	18	50	2	627
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC15 ZDHHC6	1.99e-03	24	50	2	76
GeneFamily	X-linked mental retardation\|Angiotensin receptors	ZDHHC15 DLG3	9.44e-03	53	50	2	103
CoexpressionAtlas	facebase_RNAseq_e9.5_MandArch_2500_K3	VEGFC LIMD2 BMPR1B GNE PLEKHG4 PDP1 ZFP64 SLIT3 PLXNA4 SLC39A6 DLG3 TMEM222 RNF145	2.72e-05	1259	58	13	facebase_RNAseq_e9.5_MandArch_2500_K3
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMPR1B LPP C3orf70 NTN1 ZYX CASZ1	1.78e-07	187	59	6	3912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC SHROOM4 ABLIM1 VWF PLXNA4 NTN1	2.57e-07	199	59	6	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	VEGFC VWF PLXNA4 NTN1 ABLIM3	3.55e-06	175	59	5	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BMPR1B ADAM29 NTN1 RNF145 CASZ1	3.65e-06	176	59	5	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 BMPR1B PLXNA4 NTN1 RNF145	4.07e-06	180	59	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 BMPR1B PLXNA4 SLC39A6 NTN1	4.91e-06	187	59	5	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LPP PLXNA4 C3orf70 NTN1 CASZ1	5.04e-06	188	59	5	74f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	VEGFC SHROOM4 ABLIM1 VWF ABLIM3	5.04e-06	188	59	5	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 BMPR1B PLXNA4 SLC39A6 NTN1	5.30e-06	190	59	5	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ABLIM1 FRAS1 NTN1 TECRL CASZ1	5.87e-06	194	59	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 BMPR1B SLC39A6 XKRX	4.10e-05	145	59	4	bfa196ac1db7acbfcbb2ba9f137036a95e16e091
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	LPP PLXNA4 C3orf70 NTN1	6.47e-05	163	59	4	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SHROOM4 VWF TECRL PRDM1	6.78e-05	165	59	4	7d319a112b9062efee428bef6f4534d2ce782e04
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SHROOM4 FCGBP GNE NTN1	7.44e-05	169	59	4	aec97583b23112060437b619cb429dc32f29285f
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 BMPR1B FCGBP NTN1	8.33e-05	174	59	4	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM45 VWF LPP C3orf70	8.71e-05	176	59	4	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM45 VWF LPP C3orf70	8.71e-05	176	59	4	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	VEGFC SHROOM4 STAB2 VWF	8.90e-05	177	59	4	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	9.29e-05	179	59	4	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMPR1B LPP C3orf70 CASZ1	9.29e-05	179	59	4	e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 SLIT3 PLXNA4 ABLIM3	9.50e-05	180	59	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VEGFC FRAS1 SLIT3 ABLIM3	9.70e-05	181	59	4	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 BMPR1B NTN1 RNF145	9.91e-05	182	59	4	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC ABLIM1 VWF ABLIM3	9.91e-05	182	59	4	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	ZDHHC15 PDP1 SLIT3 PLXNA4	9.91e-05	182	59	4	ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell	mild_COVID-19-NK_CD56bright\|World / disease group, cell group and cell class (v2)	ABLIM1 FRAS1 ZNF600 PLXNA4	1.01e-04	183	59	4	9a4899afac0f91203209392c5f67b3d0aa356b86
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VEGFC SHROOM4 VWF ABLIM3	1.01e-04	183	59	4	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	VEGFC SHROOM4 ABLIM1 VWF	1.01e-04	183	59	4	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ABLIM1 VWF ABLIM3 CASZ1	1.03e-04	184	59	4	7e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCell	COPD-Endothelial-VE_Venous\|COPD / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.03e-04	184	59	4	44d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCell	COPD-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.06e-04	185	59	4	4abe04198ab5047c211f8d09cdb9650fa52a3cd6
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B FCGBP SLC39A6 RNF145	1.08e-04	186	59	4	55fe25f4d0f2bc0fd4802a0a375169f2c41472fc
ToppCell	COPD-Endothelial-VE_Peribronchial\|COPD / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.08e-04	186	59	4	23c7d0e8372a71546d687278b985f761d282f92f
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	VEGFC SHROOM4 VWF C3orf70	1.10e-04	187	59	4	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PLEKHG4 C3orf70 ZNF578	1.12e-04	188	59	4	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PLEKHG4 C3orf70 ZNF578	1.12e-04	188	59	4	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM4 STAB2 GGN NTN1	1.12e-04	188	59	4	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PLEKHG4 C3orf70 ZNF578	1.12e-04	188	59	4	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM4 STAB2 GGN NTN1	1.12e-04	188	59	4	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PLEKHG4 C3orf70 ZNF578	1.12e-04	188	59	4	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 LPP C3orf70 NTN1	1.12e-04	188	59	4	879de94924de978478696fc7838e05a4d795b905
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PLEKHG4 C3orf70 ZNF578	1.12e-04	188	59	4	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	ZNF143 ZFP64 UNK PRDM1	1.15e-04	189	59	4	8b6f92ccfffc743c07201bc971b3dc1a6fa14ccc
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.15e-04	189	59	4	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABLIM1 VWF PLXNA4 NTN1	1.15e-04	189	59	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|COVID-19_Convalescent / Disease condition and Cell class	ZNF143 ZFP64 UNK PRDM1	1.15e-04	189	59	4	732e8dcffcb634ca2968f9170c9c4b31dd5d4206
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VEGFC ABLIM1 VWF ABLIM3	1.15e-04	189	59	4	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	HIVEP3 SLIT3 ABLIM3 ZYX	1.15e-04	189	59	4	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPP NTN1 ZYX CASZ1	1.17e-04	190	59	4	e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VEGFC FRAS1 BMPR1B CASZ1	1.17e-04	190	59	4	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABLIM1 ZNF600 SLIT3 YPEL1	1.19e-04	191	59	4	f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT3 PLXNA4 NTN1 ABLIM3	1.19e-04	191	59	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABLIM1 ZNF600 SLIT3 YPEL1	1.19e-04	191	59	4	1161e465c50c2071764279e01cf08b1048cce0e3
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	ABLIM1 NTN1 TECRL CASZ1	1.19e-04	191	59	4	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 BMPR1B NTN1 RNF145	1.19e-04	191	59	4	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VEGFC SHROOM4 VWF ABLIM3	1.19e-04	191	59	4	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.19e-04	191	59	4	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABLIM1 ZNF600 SLIT3 YPEL1	1.19e-04	191	59	4	7a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABLIM1 ZNF600 SLIT3 YPEL1	1.19e-04	191	59	4	c023ca893ceae19b54967096f6e2588dc39fa268
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC VWF PLXNA4 NTN1	1.22e-04	192	59	4	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VEGFC SHROOM4 ABLIM1 VWF	1.22e-04	192	59	4	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC VWF PLXNA4 NTN1	1.22e-04	192	59	4	845cc9c18b4436b07dd3ce7980052683937546d2
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPP C3orf70 NTN1 ZYX	1.22e-04	192	59	4	d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC VWF PLXNA4 NTN1	1.22e-04	192	59	4	c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	HIVEP3 FRAS1 INTS12 ZYX	1.22e-04	192	59	4	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPP C3orf70 NTN1 ZYX	1.24e-04	193	59	4	173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCell	COPD-Endothelial-VE_Arterial\|COPD / Disease state, Lineage and Cell class	SHROOM4 ABLIM1 VWF ABLIM3	1.24e-04	193	59	4	1c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	FRAS1 BMPR1B NTN1 RNF145	1.24e-04	193	59	4	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.24e-04	193	59	4	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	VEGFC SHROOM4 ABLIM1 VWF	1.24e-04	193	59	4	9ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VEGFC HIVEP3 SLIT3 ABLIM3	1.24e-04	193	59	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	SHROOM4 ABLIM1 VWF ABLIM3	1.24e-04	193	59	4	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 ABLIM1 FRAS1 GNE	1.24e-04	193	59	4	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 ABLIM1 FRAS1 GNE	1.24e-04	193	59	4	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPP C3orf70 NTN1 CASZ1	1.24e-04	193	59	4	b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.24e-04	193	59	4	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VEGFC SHROOM4 VWF ABLIM3	1.24e-04	193	59	4	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.24e-04	193	59	4	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	Mild_COVID-19-T/NK-NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	LIMD2 ABLIM1 ZNF600 YPEL1	1.24e-04	193	59	4	9c455d9d845fa230e9a61d9a5f9d6a2ccf5d7350
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.24e-04	193	59	4	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LIMD2 YPEL1 CASZ1 PRDM1	1.27e-04	194	59	4	64535db0420e53e4d777d2333b5051e63e8a3373
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	FRAS1 SLIT3 NTN1 TECRL	1.27e-04	194	59	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	IPF-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	VEGFC SHROOM4 BMPR1B VWF	1.27e-04	194	59	4	e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LPP PLXNA4 C3orf70 NTN1	1.29e-04	195	59	4	4dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	VEGFC SHROOM4 VWF ABLIM3	1.29e-04	195	59	4	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 SLIT3 ABLIM3 ZYX	1.29e-04	195	59	4	3a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell	Control-Endothelial-VE_Arterial\|Control / Disease state, Lineage and Cell class	VEGFC SHROOM4 ABLIM1 VWF	1.29e-04	195	59	4	56c66a3655820961e1390b8f4bcc5618e8d0c5a8
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIVEP3 SLIT3 ABLIM3 ZYX	1.29e-04	195	59	4	2b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	VEGFC SHROOM4 ABLIM1 VWF	1.29e-04	195	59	4	023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 BMPR1B NTN1 RNF145	1.29e-04	195	59	4	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell-NK-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LIMD2 ABLIM1 ZNF600 YPEL1	1.29e-04	195	59	4	234666fb7a1fd7e33bb7e54fd4004649ce22de70
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP GNE NTN1 CASZ1	1.29e-04	195	59	4	25703e3c2e0512ef12e7aa389fad3968c3f13905
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell-NK\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LIMD2 ABLIM1 ZNF600 YPEL1	1.29e-04	195	59	4	f0fb039f3d2e36acb258afb8b6d2fed20c395c36
ToppCell	BAL-Mild-Lymphocyte-T/NK-NK_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LIMD2 ABLIM1 ZNF600 YPEL1	1.29e-04	195	59	4	c7743d8c57584d29cca69c6405f1df6718174582
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HIVEP3 FRAS1 ABLIM3 ZYX	1.32e-04	196	59	4	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	HIVEP3 FRAS1 ABLIM3 ZYX	1.32e-04	196	59	4	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPP C3orf70 NTN1 ZYX	1.34e-04	197	59	4	ba6393671a980a1d439307601d18db70a1b1e1f3
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VEGFC SHROOM4 VWF ABLIM3	1.34e-04	197	59	4	e8e879b7634a29569061d3515d180784094a31e7
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	VEGFC SHROOM4 VWF ABLIM3	1.34e-04	197	59	4	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPP C3orf70 NTN1 ZYX	1.34e-04	197	59	4	f4f686d20821af3e6f859b96edc31827a430e3de
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP3 BMPR1B	2.92e-04	13	58	2	DOID:0050787 (implicated_via_orthology)
Disease	electrocardiography	VEGFC ZNF592 YPEL2 TMEM135 ABLIM3 CASZ1	5.99e-04	530	58	6	EFO_0004327
Disease	factor VIII measurement, Ischemic stroke	STAB2 VWF	6.36e-04	19	58	2	EFO_0004630, HP_0002140
Disease	treatment resistant depression, response to antidepressant	HIVEP3 SLIT3	7.78e-04	21	58	2	EFO_0009854, GO_0036276
Disease	response to peginterferon alfa-2a	VWF YPEL2	1.11e-03	25	58	2	EFO_0010103
Disease	factor VIII measurement, von Willebrand factor measurement	STAB2 VWF	1.29e-03	27	58	2	EFO_0004629, EFO_0004630
Disease	JT interval	YPEL2 LPP CREBBP CASZ1	1.45e-03	248	58	4	EFO_0007885
Disease	Ischemic stroke, von Willebrand factor measurement	STAB2 VWF	1.59e-03	30	58	2	EFO_0004629, HP_0002140
Disease	cutaneous squamous cell carcinoma	ZNF143 LPP	1.93e-03	33	58	2	EFO_1001927
Disease	factor VIII measurement, venous thromboembolism	STAB2 VWF	2.05e-03	34	58	2	EFO_0004286, EFO_0004630
Disease	Cleft palate, cleft lip	PHF1 PDP1 NTN1 CREBBP	2.22e-03	279	58	4	EFO_0003959, HP_0000175
Disease	factor VIII measurement	STAB2 VWF	2.82e-03	40	58	2	EFO_0004630
Disease	venous thromboembolism, von Willebrand factor measurement	STAB2 VWF	3.11e-03	42	58	2	EFO_0004286, EFO_0004629
Disease	photoreceptor cell layer thickness measurement	ABLIM3 CASZ1 PRDM1	3.12e-03	148	58	3	EFO_0803370
Disease	Paroxysmal atrial fibrillation	VWF SLIT3 CASZ1	3.61e-03	156	58	3	C0235480
Disease	familial atrial fibrillation	VWF SLIT3 CASZ1	3.61e-03	156	58	3	C3468561
Disease	Persistent atrial fibrillation	VWF SLIT3 CASZ1	3.61e-03	156	58	3	C2585653
Disease	Atrial Fibrillation	VWF SLIT3 CASZ1	3.88e-03	160	58	3	C0004238

Protein segments in the cluster

Peptide	Gene	Start	Entry
CNNKHHCHCNYLWDP	ADAM29	636	Q9UKF5
GKHYHPTCARCVRCH	ABLIM3	226	O94929
SCASRNDHCYHPLNH	ARSH	121	Q5FYA8
DKHYHPSCARCSRCN	ABLIM1	301	O14639
LKCSHFHCTFPGCRH	CASZ1	1566	Q86V15
CCYHAKHCQENKCPV	CREBBP	1826	Q92793
THSHGKCFKLHWCCH	C3orf70	46	A6NLC5
RCKCHHHCPEDSVNN	BMPR1B	31	O00238
CRHNTAGRHCHYCKE	NTN1	371	O95631
ECHNLYHRDCHKPQV	INTS12	181	Q96CB8
NLVGYCADCHHLCQH	FRAS1	801	Q86XX4
HNSCFCCKHCHTKLS	LIMD2	61	Q9BT23
LLCSCLHHLYNASCH	IRF1-AS1	41	Q8N8D9
PCHWCKYRHVCTHNV	PLXNA1	676	Q9UIW2
RCHWCKYRHVCTHDP	PLXNA4	671	Q9HCM2
HPHCFTCVMCHRSLD	LPP	496	Q93052
LHHAQASCCRPSYCG	KRTAP1-5	146	Q9BYS1
SCPCKCYCHHQPRHR	GGN	591	Q86UU5
YCHHKHLCCSSSYIP	PDP1	26	Q9P0J1
CQHCKCPREEHAVHA	PRICKLE3	46	O43900
IRHAITKLAHYHVCC	GNE	146	Q9Y223
FCPLHCPAHSHYSIC	FCGBP	5116	Q9Y6R7
MHKHQHCCKCPECYE	DLG3	1	Q92796
LFHRHRHQSPDCCEC	LCE2A	76	Q5TA79
HRSHCHRPKSSNCYG	LCE4A	66	Q5TA78
SCEKCRHAYHQDCHV	PHF1	106	O43189
HRPHSGVFHCCTFCS	TRIM45	501	Q9H8W5
CHCHHAATIAACRRP	PLEKHG4	691	Q58EX7
CIRCSVCYHNPQHSA	SHROOM4	931	Q9ULL8
PHKCSQCHKNYIHLC	PRDM1	686	O75626
YVPRGCKNKCHSHFH	SLC39A6	531	Q13433
ACSAFKCHHGQCHIS	SLIT3	1411	O75094
CKVCQAYKAPRSHHC	ZDHHC6	101	Q9H6R6
NCHRTYSCIHCRAHL	YPEL1	16	O60688
KAYHPGCFTCVVCHR	TRIP6	356	Q15654
HTHSKPYNCNHCGKT	ZNF143	411	P52747
FHHQTCSCYRRPCTN	VEGFC	376	P49767
ECHLCGKAFSHCSHL	ZNF596	336	Q8TC21
TCHHRCHTGEKPYKC	ZNF578	331	Q96N58
SLVYNHCEHGCPRHC	VWF	2206	P04275
YHKPFHCIHKTCNSS	RLF	1306	Q13129
CAHQRIHAHKSPYCC	ZNF592	756	Q92610
HTDVRPYVCKHCHFA	HIVEP3	1776	Q5T1R4
HGPRHRCCKHYEDNC	TMEM135	236	Q86UB9
CLRKICHPHAHCTYL	STAB2	241	Q8WWQ8
IHRHNEIHYKCGKCH	ZNF518A	226	Q6AHZ1
EIHYKCGKCHHVCFT	ZNF518A	231	Q6AHZ1
CPVHKDRSCYICHRQ	TNKS2	1081	Q9H2K2
SCHRTYSCIHCRAHL	YPEL2	16	Q96QA6
EYKHRMHNLCCDNCH	TMEM222	131	Q9H0R3
KAYHPHCFTCVVCAR	ZYX	461	Q15942
KYCQTDHHHHGCCEP	ZNF800	6	Q2TB10
PVVHLACFCHCIHYI	TECRL	181	Q5HYJ1
VVDYLHCVCCHQHPR	XKRX	416	Q6PP77
HKCTQHRPYTCFHWH	UNK	51	Q9C0B0
HKQYLTCHCRCHTGE	ZNF600	201	Q6ZNG1
YVQETCPLCHCHLKN	RNF145	566	Q96MT1
CHTSVKPHKCHLCDY	ZFP64	351	Q9NTW7
HVVHTHCKPYTCSTC	ZNF76	336	P36508
YRCNVCGKVFHHISH	ZNF83	261	P51522
CDRCHLIKPDRCHHC	ZDHHC15	131	Q96MV8