Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

5.42e-062472GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

5.42e-062472GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

1.62e-053472GO:0043993
GeneOntologyMolecularFunctiondeaminase binding

HNRNPCL1 HNRNPCL2

3.24e-054472GO:1990827
GeneOntologyMolecularFunctionmethylated histone binding

CBX3 CHD8 KDM5A ZMYND8

4.97e-0586474GO:0035064
GeneOntologyMolecularFunctionmolecular adaptor activity

SFMBT1 NOLC1 HNRNPCL1 RERE KDM5A CREBBP EP300 WNK3 HNRNPCL2 SYNE2 SH3KBP1 ZMYND8

5.16e-0513564712GO:0060090
GeneOntologyMolecularFunctionmethylation-dependent protein binding

CBX3 CHD8 KDM5A ZMYND8

5.43e-0588474GO:0140034
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

SFMBT1 NOLC1 HNRNPCL1 RERE KDM5A CREBBP EP300 WNK3 HNRNPCL2 SYNE2 ZMYND8

6.09e-0511604711GO:0030674
GeneOntologyMolecularFunctionTFIIB-class transcription factor binding

NOLC1 CREBBP

8.09e-056472GO:0001093
GeneOntologyMolecularFunctionmodification-dependent protein binding

CBX3 CHD8 KDM5A EP300 ZMYND8

1.20e-04206475GO:0140030
GeneOntologyMolecularFunctionhistone binding

SFMBT1 CBX3 CHD8 KDM5A ZMYND8

3.86e-04265475GO:0042393
GeneOntologyMolecularFunctionN6-methyladenosine-containing RNA reader activity

HNRNPCL1 HNRNPCL2

5.58e-0415472GO:1990247
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

5.58e-0415472GO:0010484
GeneOntologyMolecularFunctionp53 binding

CHD8 CREBBP EP300

7.91e-0477473GO:0002039
GeneOntologyMolecularFunctionprotein domain specific binding

NOLC1 CBX3 CHD8 HNRNPCL1 CREBBP HNRNPCL2 SH3KBP1 ZMYND8

9.06e-04875478GO:0019904
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

1.11e-0321472GO:0042975
GeneOntologyMolecularFunctionprotein-RNA adaptor activity

HNRNPCL1 HNRNPCL2

1.45e-0324472GO:0140517
GeneOntologyMolecularFunctiontelomerase RNA binding

HNRNPCL1 HNRNPCL2

1.57e-0325472GO:0070034
GeneOntologyMolecularFunctionchromatin binding

SFMBT1 CBX3 CHD8 RERE KDM5A CREBBP EP300

1.60e-03739477GO:0003682
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

NOLC1 CREBBP

1.83e-0327472GO:0001091
GeneOntologyMolecularFunctiontranscription coregulator activity

SFMBT1 RERE KDM5A CREBBP EP300 ZMYND8

1.95e-03562476GO:0003712
GeneOntologyMolecularFunctiondynein complex binding

APC CNTRL

1.97e-0328472GO:0070840
GeneOntologyMolecularFunctiontranscription corepressor activity

SFMBT1 RERE CREBBP ZMYND8

2.04e-03229474GO:0003714
GeneOntologyMolecularFunctionacetylation-dependent protein binding

EP300 ZMYND8

2.41e-0331472GO:0140033
GeneOntologyMolecularFunctionmolecular function inhibitor activity

NOLC1 HNRNPCL1 KDM5A WNK3 PPP1R12B HNRNPCL2

2.62e-03596476GO:0140678
GeneOntologyMolecularFunctionbeta-catenin binding

APC CHD8 EP300

2.83e-03120473GO:0008013
GeneOntologyMolecularFunctionpoly(U) RNA binding

HNRNPCL1 HNRNPCL2

2.90e-0334472GO:0008266
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

3.43e-0337472GO:0043425
GeneOntologyMolecularFunctionenzyme inhibitor activity

NOLC1 HNRNPCL1 KDM5A PPP1R12B HNRNPCL2

3.47e-03435475GO:0004857
GeneOntologyMolecularFunctionpoly-pyrimidine tract binding

HNRNPCL1 HNRNPCL2

3.80e-0339472GO:0008187
GeneOntologyMolecularFunctiontranscription coregulator binding

CBX3 CREBBP EP300

4.37e-03140473GO:0001221
GeneOntologyMolecularFunctiontranscription coactivator activity

RERE KDM5A CREBBP EP300

5.55e-03303474GO:0003713
GeneOntologyMolecularFunctionhistone acetyltransferase activity

CREBBP EP300

6.42e-0351472GO:0004402
GeneOntologyMolecularFunctionchromatin DNA binding

KDM5A CREBBP EP300

7.11e-03167473GO:0031490
GeneOntologyMolecularFunctiontranscription coactivator binding

CREBBP EP300

7.18e-0354472GO:0001223
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

CREBBP EP300

7.44e-0355472GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

CREBBP EP300

8.80e-0360472GO:0034212
GeneOntologyMolecularFunctionDNA helicase activity

NAV2 CHD8

9.37e-0362472GO:0003678
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

NOLC1 CREBBP

9.96e-0364472GO:0140296
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

NOLC1 CREBBP

1.06e-0266472GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

NOLC1 CREBBP

1.06e-0266472GO:0001098
GeneOntologyMolecularFunctionribonucleoprotein complex binding

NOLC1 HNRNPCL1 HNRNPCL2

1.26e-02206473GO:0043021
GeneOntologyMolecularFunctionN-acetyltransferase activity

CREBBP EP300

1.45e-0278472GO:0008080
GeneOntologyBiologicalProcesschromatin organization

SFMBT1 CBX3 NRDE2 CHD8 RERE TEX15 KDM5A CREBBP EP300 ZMYND8

2.73e-058964710GO:0006325
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

3.04e-054472GO:0018076
GeneOntologyBiologicalProcessprotein-DNA complex organization

SFMBT1 CBX3 NRDE2 CHD8 RERE TEX15 KDM5A CREBBP EP300 ZMYND8

6.84e-059994710GO:0071824
GeneOntologyBiologicalProcessnegative regulation of mRNA modification

HNRNPCL1 HNRNPCL2

7.58e-056472GO:0090367
GeneOntologyBiologicalProcessregulation of mRNA modification

HNRNPCL1 HNRNPCL2

1.06e-047472GO:0090365
GeneOntologyCellularComponentnuclear body

FANCD2 NOLC1 NRDE2 PPIG RERE CMYA5 THOC2 SAP130 CREBBP S100PBP

2.60e-059034710GO:0016604
GeneOntologyCellularComponentnucleoplasmic periphery of the nuclear pore complex

HNRNPCL1 HNRNPCL2

7.38e-056472GO:1990826
GeneOntologyCellularComponentnuclear protein-containing complex

NOLC1 CBX3 CHD8 HNRNPCL1 GCFC2 RERE THOC2 SAP130 CREBBP HNRNPCL2 SYNE2

1.87e-0413774711GO:0140513
GeneOntologyCellularComponentnuclear speck

NRDE2 PPIG CMYA5 THOC2 SAP130 S100PBP

3.90e-04431476GO:0016607
HumanPhenoPilomatrixoma

APC CREBBP EP300

3.07e-069183HP:0030434
HumanPhenoKeloids

APC CREBBP EP300

1.04e-0513183HP:0010562
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

1.18e-052182HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

1.18e-052182HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

1.18e-052182HP:0001042
HumanPhenoSkin appendage neoplasm

APC CREBBP EP300

2.93e-0518183HP:0012842
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

3.53e-053182HP:0008752
HumanPhenoPhobia

CREBBP EP300

3.53e-053182HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

3.53e-053182HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

3.53e-053182HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

3.53e-053182HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

3.53e-053182HP:0005895
HumanPhenoAbsent earlobe

CEP152 CREBBP EP300

4.07e-0520183HP:0000387
HumanPhenoBlepharophimosis

FANCD2 CEP152 RERE CREBBP EP300

6.34e-05129185HP:0000581
HumanPhenoTrichiasis

CREBBP EP300

7.05e-054182HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

7.05e-054182HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

7.05e-054182HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

7.05e-054182HP:0006200
HumanPhenoVascular ring

CREBBP EP300

7.05e-054182HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

7.05e-054182HP:0031207
HumanPhenoSimple ear

RERE CREBBP EP300

7.16e-0524183HP:0020206
HumanPhenoCafe-au-lait spot

FANCD2 APC RERE CREBBP EP300

8.45e-05137185HP:0000957
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

1.17e-045182HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

1.17e-045182HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

1.17e-045182HP:0030421
HumanPhenoAbnormal hip joint morphology

FANCD2 APC CEP152 RERE THOC2 CREBBP EP300 SIL1

1.27e-04490188HP:0001384
HumanPhenoBroad eyebrow

RERE CREBBP EP300

1.28e-0429183HP:0011229
HumanPhenoHip dysplasia

CEP152 RERE THOC2 CREBBP EP300 SIL1

1.39e-04247186HP:0001385
HumanPhenoAvascular necrosis of the capital femoral epiphysis

CREBBP EP300 SIL1

1.42e-0430183HP:0005743
HumanPhenoAbnormal hip bone morphology

FANCD2 APC CEP152 RERE THOC2 CREBBP EP300 WNK3 SIL1

1.47e-04653189HP:0003272
HumanPhenoAbnormal synovial membrane morphology

FANCD2 APC CEP152 RERE THOC2 CREBBP EP300 SIL1

1.53e-04503188HP:0005262
HumanPhenoLarge foramen magnum

CREBBP EP300

1.75e-046182HP:0002700
HumanPhenoAbnormal nasal dorsum morphology

APC RPGRIP1 CEP152 RERE CREBBP EP300

1.92e-04262186HP:0011119
HumanPhenoDeviated nasal septum

CREBBP EP300

2.45e-047182HP:0004411
HumanPhenoAccessory spleen

RPGRIP1 CREBBP EP300

2.67e-0437183HP:0001747
HumanPhenoMotor stereotypy

CHD8 CEP152 RERE THOC2 CREBBP EP300

2.77e-04280186HP:0000733
HumanPhenoConvex nasal ridge

APC CEP152 CREBBP EP300

2.84e-0495184HP:0000444
HumanPhenoAbnormal pelvic girdle bone morphology

FANCD2 APC CEP152 RERE THOC2 CREBBP EP300 WNK3 SIL1

3.50e-04730189HP:0002644
HumanPhenoObesity

CHD8 RERE THOC2 CREBBP EP300 SYNE2 SH3KBP1

3.78e-04425187HP:0001513
HumanPhenoCervical cord compression

CREBBP EP300

4.18e-049182HP:0002341
HumanPhenoJuvenile aseptic necrosis

CREBBP EP300 SIL1

4.19e-0443183HP:0100323
HumanPhenoSpinal cord compression

APC CREBBP EP300

4.48e-0444183HP:0002176
HumanPhenoPtosis

FANCD2 APC CHD8 RERE ZFHX4 CREBBP EP300 WNK3 SYNE2

4.49e-04754189HP:0000508
HumanPhenoHypermelanotic macule

FANCD2 APC RERE CREBBP EP300

5.12e-04201185HP:0001034
HumanPhenoFrontal hirsutism

CREBBP EP300

5.22e-0410182HP:0011335
HumanPhenoLower extremity joint dislocation

FANCD2 APC CREBBP EP300 WNK3 SIL1

5.52e-04318186HP:0030311
HumanPhenoAbnormality of the thigh

FANCD2 CREBBP EP300 WNK3 SIL1 SYNE2

5.90e-04322186HP:0001439
HumanPhenoOverweight

CHD8 THOC2 CREBBP

6.17e-0449183HP:0025502
HumanPheno11 pairs of ribs

CEP152 RERE WNK3

6.17e-0449183HP:0000878
HumanPhenoSelf-injurious behavior

CEP152 RERE THOC2 CREBBP EP300

6.27e-04210185HP:0100716
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

6.37e-0411182HP:0031251
HumanPhenoSelf-mutilation

THOC2 CREBBP EP300

6.94e-0451183HP:0000742
HumanPhenoSingle transverse palmar crease

APC RERE THOC2 CREBBP EP300

6.98e-04215185HP:0000954
HumanPhenoUpslanted palpebral fissure

FANCD2 CEP295 CEP152 RERE CREBBP EP300

7.07e-04333186HP:0000582
HumanPhenoAbnormal proximal phalanx morphology of the hand

FANCD2 CREBBP EP300

7.35e-0452183HP:0009834
HumanPhenoAplasia/Hypoplasia of the earlobes

CEP152 CREBBP EP300

7.77e-0453183HP:0009906
HumanPhenoAplasia/hypoplasia affecting bones of the axial skeleton

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE CREBBP EP300 WNK3

8.15e-0410081810HP:0009122
HumanPhenoShort thumb

FANCD2 APC CREBBP EP300

8.60e-04127184HP:0009778
HumanPhenoFacial grimacing

CREBBP EP300

8.99e-0413182HP:0000273
HumanPhenoLow hanging columella

CEP295 CREBBP EP300

9.14e-0456183HP:0009765
HumanPhenoIncreased body weight

CHD8 RERE THOC2 CREBBP EP300 SYNE2 SH3KBP1

9.16e-04491187HP:0004324
HumanPhenoHypertelorism

FANCD2 APC RPGRIP1 CHD8 RERE THOC2 CREBBP EP300 WNK3

9.33e-04830189HP:0000316
HumanPhenoDownslanted palpebral fissures

APC CHD8 CEP295 CEP152 RERE CREBBP EP300

9.85e-04497187HP:0000494
HumanPhenoMacule

FANCD2 APC RERE CREBBP EP300

1.03e-03234185HP:0012733
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

1.05e-0314182HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

1.05e-0314182HP:0012304
HumanPhenoParietal foramina

CREBBP EP300

1.05e-0314182HP:0002697
HumanPhenoMicrognathia

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE CREBBP EP300

1.05e-03843189HP:0000347
HumanPhenoAplasia/Hypoplasia of the mandible

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE CREBBP EP300

1.07e-03845189HP:0009118
HumanPhenoPatent foramen ovale

CEP295 RERE CREBBP EP300

1.08e-03135184HP:0001655
HumanPhenoIrregular hyperpigmentation

FANCD2 APC RERE CREBBP EP300

1.11e-03238185HP:0007400
HumanPhenoAbnormal earlobe morphology

CEP152 RERE CREBBP EP300

1.14e-03137184HP:0000363
HumanPhenoPes planus

FANCD2 CHD8 CEP152 CREBBP EP300 SIL1

1.15e-03365186HP:0001763
HumanPhenoRestricted or repetitive behaviors or interests

CHD8 CEP152 RERE THOC2 CREBBP EP300

1.20e-03368186HP:0031432
HumanPhenoDuplication of phalanx of toe

CREBBP EP300

1.21e-0315182HP:0010181
HumanPhenoSocial and occupational deterioration

CREBBP EP300

1.21e-0315182HP:0007086
HumanPhenoPerseverative thought

CHD8 CEP152 RERE THOC2 CREBBP EP300

1.36e-03377186HP:0030223
HumanPhenoSquare face

CREBBP EP300

1.37e-0316182HP:0000321
HumanPhenoAbnormal pinna morphology

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE THOC2 CREBBP EP300 WNK3

1.46e-0312991811HP:0000377
HumanPhenoAbnormality of the ureter

FANCD2 RPGRIP1 CEP152 RERE CREBBP EP300

1.48e-03383186HP:0000069
HumanPhenoDuplication involving bones of the feet

RPGRIP1 RERE CREBBP EP300

1.49e-03147184HP:0009136
HumanPhenoFoot polydactyly

RPGRIP1 RERE CREBBP EP300

1.49e-03147184HP:0001829
HumanPhenoDisordered formal thought process

CHD8 CEP152 RERE THOC2 CREBBP EP300

1.54e-03386186HP:0025769
HumanPhenoPremature thelarche

CREBBP EP300

1.55e-0317182HP:0010314
HumanPhenoAplasia/Hypoplasia of the thumb

FANCD2 APC CREBBP EP300

1.60e-03150184HP:0009601
HumanPhenoMissing ribs

CEP152 RERE WNK3

1.61e-0368183HP:0000921
HumanPhenoJoint dislocation

FANCD2 APC CREBBP EP300 WNK3 SIL1

1.63e-03390186HP:0001373
HumanPhenoAbnormality of the palmar creases

APC RERE THOC2 CREBBP EP300

1.65e-03260185HP:0010490
HumanPhenoNystagmus

FANCD2 APC RPGRIP1 CHD8 RERE THOC2 CREBBP EP300 WNK3 SIL1

1.70e-0311021810HP:0000639
HumanPhenomacules

FANCD2 APC RERE CREBBP EP300

1.71e-03262185HP:0200031
HumanPhenoFacial hirsutism

CREBBP EP300

1.75e-0318182HP:0009937
HumanPhenoAbnormal palmar dermatoglyphics

APC RERE THOC2 CREBBP EP300

1.80e-03265185HP:0001018
HumanPhenoPatellar dislocation

CREBBP EP300 WNK3

1.82e-0371183HP:0002999
HumanPhenoAbnormality of the outer ear

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE THOC2 CREBBP EP300 WNK3

1.88e-0313371811HP:0000356
HumanPhenoAbnormal mandible morphology

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE CREBBP EP300 WNK3

1.91e-0311181810HP:0000277
HumanPhenoAplasia/Hypoplasia involving bones of the skull

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE CREBBP EP300

1.93e-03915189HP:0009116
HumanPhenoAbnormal thought pattern

CHD8 CEP152 RERE THOC2 CREBBP EP300

1.95e-03404186HP:5200269
HumanPhenoAplasia/hypoplasia involving the skeleton

FANCD2 APC RPGRIP1 CHD8 CEP295 CEP152 RERE CREBBP EP300 WNK3 SIL1

1.96e-0313431811HP:0009115
HumanPhenoAbnormal involuntary eye movements

FANCD2 APC RPGRIP1 CHD8 RERE THOC2 CREBBP EP300 WNK3 SIL1

1.98e-0311231810HP:0012547
HumanPhenoAtypical scarring of skin

APC CREBBP EP300

2.05e-0374183HP:0000987
Domain-

CREBBP EP300

5.93e-0624621.10.246.20
Domainzf-TAZ

CREBBP EP300

5.93e-062462PF02135
DomainZF_TAZ

CREBBP EP300

5.93e-062462PS50134
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

5.93e-062462IPR014744
DomainHAT_KAT11

CREBBP EP300

5.93e-062462PF08214
DomainKIX

CREBBP EP300

5.93e-062462PS50952
DomainZnF_TAZ

CREBBP EP300

5.93e-062462SM00551
DomainCBP_P300_HAT

CREBBP EP300

5.93e-062462IPR031162
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

5.93e-062462IPR013178
DomainDUF902

CREBBP EP300

5.93e-062462PF06001
Domain-

CREBBP EP300

5.93e-0624621.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

5.93e-062462IPR010303
DomainKAT11

CREBBP EP300

5.93e-062462SM01250
Domain-

CREBBP EP300

5.93e-0624621.10.1630.10
DomainZnf_TAZ

CREBBP EP300

5.93e-062462IPR000197
DomainKIX_dom

CREBBP EP300

5.93e-062462IPR003101
DomainCreb_binding

CREBBP EP300

5.93e-062462PF09030
DomainKIX

CREBBP EP300

5.93e-062462PF02172
DomainCBP_P300_HAT

CREBBP EP300

5.93e-062462PS51727
DomainhnRNP_C

HNRNPCL1 HNRNPCL2

8.85e-056462IPR017347
DomainNuc_rcpt_coact

CREBBP EP300

8.85e-056462IPR009110
DomainBromodomain

CREBBP EP300 ZMYND8

1.11e-0438463PF00439
DomainBROMODOMAIN_2

CREBBP EP300 ZMYND8

1.40e-0441463PS50014
DomainBROMO

CREBBP EP300 ZMYND8

1.50e-0442463SM00297
DomainBromodomain

CREBBP EP300 ZMYND8

1.50e-0442463IPR001487
Domain-

CREBBP EP300 ZMYND8

1.50e-04424631.20.920.10
DomainZF_ZZ_2

CREBBP EP300

8.85e-0418462PS50135
DomainZF_ZZ_1

CREBBP EP300

8.85e-0418462PS01357
DomainZZ

CREBBP EP300

8.85e-0418462PF00569
DomainZnf_ZZ

CREBBP EP300

9.88e-0419462IPR000433
DomainZnF_ZZ

CREBBP EP300

9.88e-0419462SM00291
DomainChromo_domain

CBX3 CHD8

1.58e-0324462IPR023780
DomainChromo

CBX3 CHD8

1.86e-0326462PF00385
DomainBromodomain_CS

CREBBP EP300

1.86e-0326462IPR018359
DomainCHROMO_2

CBX3 CHD8

2.15e-0328462PS50013
DomainCHROMO_1

CBX3 CHD8

2.15e-0328462PS00598
DomainChromodomain-like

CBX3 CHD8

2.81e-0332462IPR016197
DomainCHROMO

CBX3 CHD8

2.98e-0333462SM00298
DomainChromo/shadow_dom

CBX3 CHD8

2.98e-0333462IPR000953
DomainBROMODOMAIN_1

CREBBP EP300

3.74e-0337462PS00633
DomainARM-like

APC PSMD1 FHOD3 SIL1

4.33e-03270464IPR011989
PathwayBIOCARTA_PITX2_PATHWAY

APC CREBBP EP300

5.22e-0615333MM1439
PathwayBIOCARTA_PITX2_PATHWAY

APC CREBBP EP300

6.41e-0616333M8516
PathwayBIOCARTA_TGFB_PATHWAY

APC CREBBP EP300

7.77e-0617333MM1509
PathwayBIOCARTA_TGFB_PATHWAY

APC CREBBP EP300

1.10e-0519333M18933
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

5.29e-055332MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

5.29e-055332M48020
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

5.29e-055332M27228
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

5.29e-055332M48023
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

7.92e-056332M22062
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

PSMD1 CEP152 EP300 PPP1R12B CNTRL

9.39e-05200335M864
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.11e-047332MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.47e-048332M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

1.47e-048332M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

1.47e-048332M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

1.47e-048332M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

1.89e-049332M47451
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

APC PSMD1 CHD8 CREBBP EP300

1.92e-04233335M27099
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

2.36e-0410332M27945
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

2.88e-0411332MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

2.88e-0411332M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

2.88e-0411332M26924
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

3.46e-0412332M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

3.46e-0412332M27765
PathwayKEGG_WNT_SIGNALING_PATHWAY

APC CHD8 CREBBP EP300

4.06e-04151334M19428
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

4.75e-0414332M27808
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

APC PSMD1 CHD8 EP300

4.83e-04158334MM14791
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

5.47e-0415332MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

5.47e-0415332M10183
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

5.47e-0415332M953
PathwayREACTOME_FORMATION_OF_PARAXIAL_MESODERM

PSMD1 CREBBP EP300

5.51e-0469333M46439
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

6.25e-0416332M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

6.25e-0416332MM1420
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

6.25e-0416332M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

6.25e-0416332M27940
PathwayREACTOME_CELLULAR_RESPONSE_TO_HYPOXIA

PSMD1 CREBBP EP300

7.04e-0475333M641
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

7.07e-0417332M48025
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

7.94e-0418332M26942
PathwayPID_BETA_CATENIN_NUC_PATHWAY

APC CHD8 EP300

8.49e-0480333M223
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

8.86e-0419332M46442
PathwayREACTOME_SIGNALING_BY_NOTCH4

PSMD1 CREBBP EP300

9.13e-0482333M594
PathwayREACTOME_SIGNALING_BY_WNT

APC PSMD1 CHD8 CREBBP EP300

9.44e-04330335M7847
PathwayREACTOME_CELL_CYCLE

PSMD1 CEP152 TEX15 EP300 PPP1R12B CNTRL SYNE2

9.46e-04694337M543
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

9.83e-0420332M27881
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

CEP152 PPP1R12B CNTRL

1.08e-0387333M27194
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

1.09e-0321332M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

1.09e-0321332M27485
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

1.19e-0322332MM1443
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

1.19e-0322332MM1370
PathwayBIOCARTA_WNT_PATHWAY

APC CREBBP

1.30e-0323332MM1527
PathwayWP_15Q133_COPY_NUMBER_VARIATION_SYNDROME

FANCD2 CREBBP

1.30e-0323332M39883
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

1.30e-0323332M2821
PathwayBIOCARTA_WNT_PATHWAY

APC CREBBP

1.42e-0324332M16517
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

1.42e-0324332M13404
PathwayREACTOME_NUCLEAR_EVENTS_MEDIATED_BY_NFE2L2

PSMD1 CREBBP EP300

1.44e-0396333M45026
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

PSMD1 CREBBP EP300

1.44e-0396333M27784
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.54e-0325332M27880
PathwayREACTOME_RHOBTB2_GTPASE_CYCLE

HNRNPCL1 HNRNPCL2

1.54e-0325332MM15606
PathwayREACTOME_RHOBTB1_GTPASE_CYCLE

HNRNPCL1 HNRNPCL2

1.54e-0325332MM15608
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

APC CREBBP EP300

1.67e-03101333MM15829
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

APC CREBBP EP300

1.67e-03101333M39387
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP EP300

1.67e-0326332M2499
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

1.67e-0326332M32
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

1.93e-0328332M27254
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

2.22e-0330332M207
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

2.22e-0330332M936
PathwayREACTOME_SIGNALING_BY_WNT

APC PSMD1 CHD8 EP300

2.24e-03239334MM14756
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP EP300

2.52e-0332332M39521
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

APC CHD8

2.52e-0332332MM14975
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

CREBBP EP300

2.84e-0334332M39771
PathwayPID_HIF2PATHWAY

CREBBP EP300

2.84e-0334332M44
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

CREBBP EP300

3.01e-0335332M48246
PathwayREACTOME_KEAP1_NFE2L2_PATHWAY

PSMD1 CREBBP EP300

3.06e-03125333M45021
PathwayREACTOME_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

KDM5A CREBBP EP300

3.27e-03128333M48019
PathwayREACTOME_GASTRULATION

PSMD1 CREBBP EP300

3.34e-03129333M46433
PathwayREACTOME_RHOBTB_GTPASE_CYCLE

HNRNPCL1 HNRNPCL2

3.36e-0337332MM15683
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

3.54e-0338332M27757
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CREBBP EP300

3.54e-0338332M27255
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM5A SAP130 CREBBP EP300

3.57e-03272334M29619
PathwayPID_FOXM1_PATHWAY

CREBBP EP300

3.92e-0340332M176
PathwayPID_IFNG_PATHWAY

CREBBP EP300

3.92e-0340332M161
PathwayPID_P53_DOWNSTREAM_PATHWAY

APC CREBBP EP300

3.96e-03137333M145
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

APC PSMD1 CREBBP EP300 CNTRL

4.19e-03464335M27547
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

PSMD1 CREBBP EP300

4.21e-03140333M27484
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

CREBBP EP300

4.32e-0342332M17541
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

APC CHD8

4.32e-0342332M27272
PathwayREACTOME_HATS_ACETYLATE_HISTONES

SAP130 CREBBP EP300

4.38e-03142333M27233
PathwayWP_ENDODERM_DIFFERENTIATION

SFMBT1 APC ZFHX4

4.46e-03143333M39591
PathwayWP_MALE_INFERTILITY

TEX15 CREBBP EP300

4.64e-03145333M39856
PathwayPID_HNF3A_PATHWAY

CREBBP EP300

4.73e-0344332M285
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

CREBBP EP300

4.73e-0344332M27295
PathwayPID_PS1_PATHWAY

APC CREBBP

5.16e-0346332M70
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP EP300

5.38e-0347332M7946
PathwayPID_HES_HEY_PATHWAY

CREBBP EP300

5.60e-0348332M288
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

5.60e-0348332M611
PathwayPID_FOXO_PATHWAY

CREBBP EP300

5.83e-0349332M136
PathwayREACTOME_HEME_SIGNALING

CREBBP EP300

5.83e-0349332M41832
PathwayREACTOME_SIGNALING_BY_NOTCH3

CREBBP EP300

5.83e-0349332M618
PathwayREACTOME_REGULATION_OF_RUNX3_EXPRESSION_AND_ACTIVITY

PSMD1 EP300

6.55e-0352332MM15536
PathwayBIOCARTA_PPARA_PATHWAY

CREBBP EP300

6.55e-0352332M2404
PathwayPID_NFAT_3PATHWAY

CREBBP EP300

6.80e-0353332M113
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

SFMBT1 APC CBX3 PSMD1 CHD8 RERE ZFHX4 KDM5A ZMYND8 S100PBP

1.97e-10418471034709266
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

FANCD2 NOLC1 CBX3 CHD8 CEP295 RERE ZFHX4 KDM5A SAP130 CREBBP EP300 ZMYND8

2.08e-081116471231753913
Pubmed

Human transcription factor protein interaction networks.

NOLC1 PSMD1 CHD8 CEP152 RERE ZFHX4 KDM5A SAP130 CREBBP EP300 SYNE2 SH3KBP1 ZMYND8

3.44e-081429471335140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FAM133B NAV2 NOLC1 CBX3 RPGRIP1 PSMD1 CEP295 HNRNPCL1 KDM5A PPP1R12B HNRNPCL2 CNTRL SYNE2

3.82e-081442471335575683
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

SFMBT1 KDM5A CREBBP EP300 ZMYND8

5.82e-087547525593309
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

APC CHD8 CREBBP EP300

1.32e-073447430894540
Pubmed

A human MAP kinase interactome.

NAV2 APC CBX3 PSMD1 CHD8 CREBBP EP300 CNTRL

2.68e-0748647820936779
Pubmed

The protein interaction landscape of the human CMGC kinase group.

FANCD2 SFMBT1 APC PSMD1 PPIG HNRNPCL1 DYRK4 CREBBP EP300

3.34e-0769547923602568
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FANCD2 NOLC1 PSMD1 PPIG GCFC2 RERE THOC2 KDM5A ZMYND8

8.17e-0777447915302935
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

FANCD2 NOLC1 CBX3 CHD8 PPIG THOC2 SAP130 CREBBP EP300 ZMYND8

8.26e-071014471032416067
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

FAM133B NOLC1 CBX3 CHD8 PPIG THOC2 KDM5A SAP130 NKAPD1 ADD2 ZMYND8

1.10e-061318471130463901
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

APC NOLC1 CBX3 NRDE2 PPIG HNRNPCL1 THOC2 KDM5A ADD2 ZMYND8

1.48e-061082471038697112
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

APC NOLC1 NRDE2 PSMD1 FAM216A CEP295 THOC2 NKAPD1 DDHD1 CNTRL

1.51e-061084471011544199
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

1.79e-06247227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

1.79e-06247234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

1.79e-06247219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

1.79e-06247215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

1.79e-06247229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

1.79e-06247224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

1.79e-06247233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

1.79e-0624729018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

1.79e-06247224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

1.79e-06247230135524
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

1.79e-06247239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

1.79e-06247216596650
Pubmed

Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.

KDM5A ZMYND8

1.79e-06247228572115
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

1.79e-06247229217654
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

1.79e-06247220717166
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

1.79e-06247210049825
Pubmed

Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility.

FANCD2 TEX15

1.79e-06247228386063
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

1.79e-06247227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

1.79e-06247229170789
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

1.79e-06247225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

1.79e-06247211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

1.79e-06247221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

1.79e-06247212646247
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

1.79e-06247232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

1.79e-06247219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

1.79e-06247224522976
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

1.79e-06247211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

1.79e-06247221847097
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

1.79e-06247211963968
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

1.79e-06247234813504
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

1.79e-0624729528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

1.79e-06247212696060
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

1.79e-06247220301699
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

1.79e-06247236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

1.79e-06247224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

1.79e-06247237816914
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

1.79e-06247212242694
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

1.79e-06247211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

1.79e-06247210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

1.79e-06247231182547
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

1.79e-06247235502657
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

1.79e-06247230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

1.79e-06247231898871
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

1.79e-06247227648933
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

1.79e-06247230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

1.79e-06247227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

1.79e-06247219272189
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

1.79e-06247210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

1.79e-06247237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

1.79e-06247212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

1.79e-06247215641773
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

1.79e-06247232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

1.79e-0624729733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

1.79e-06247230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

1.79e-06247221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

1.79e-0624729811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

1.79e-06247224089570
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

1.79e-06247233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

1.79e-06247234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

1.79e-06247222177454
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

1.79e-06247215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

1.79e-06247239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

1.79e-06247222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

1.79e-06247234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

1.79e-06247234019788
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NAV2 APC NOLC1 CEP152 DYRK4 KDM5A WNK3 SYNE2 PLEKHA3

1.96e-0686147936931259
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

PSMD1 DDHD1 PPP1R12B ADD2

2.11e-066747429254152
Pubmed

The functional interactome landscape of the human histone deacetylase family.

GCFC2 RERE KDM5A SAP130 SYNE2 ZMYND8

2.52e-0628947623752268
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NAV2 APC NOLC1 CBX3 PSMD1 CHD8 THOC2

4.84e-0650347716964243
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP EP300

5.36e-06347214716005
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

5.36e-06347218070920
Pubmed

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

CREBBP EP300

5.36e-06347221967847
Pubmed

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

CREBBP EP300

5.36e-06347219252086
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

5.36e-06347227903646
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

5.36e-06347212748286
Pubmed

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

CREBBP EP300

5.36e-06347210075656
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

5.36e-06347224340053
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

5.36e-06347219273602
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

5.36e-06347215649887
Pubmed

Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.

CREBBP EP300

5.36e-06347222179676
Pubmed

CBP/p300 are bimodal regulators of Wnt signaling.

CREBBP EP300

5.36e-06347217410209
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

5.36e-06347226951377
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

5.36e-06347221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

5.36e-06347212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

5.36e-06347216237459
Pubmed

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

CREBBP EP300

5.36e-06347212384703
Pubmed

Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.

CREBBP EP300

5.36e-06347210350644
InteractionHDAC1 interactions

FANCD2 SFMBT1 APC NOLC1 PSMD1 CHD8 RERE ZFHX4 KDM5A SAP130 CREBBP EP300 SYNE2 ZMYND8 S100PBP

1.65e-0811084715int:HDAC1
InteractionKDM1A interactions

FANCD2 SFMBT1 APC CBX3 PSMD1 CHD8 CEP152 RERE ZFHX4 THOC2 KDM5A EP300 ZMYND8 S100PBP

1.72e-089414714int:KDM1A
InteractionHNRNPCL1 interactions

FANCD2 NOLC1 PPIG HNRNPCL1 NKAPD1 HNRNPCL2

1.94e-06161476int:HNRNPCL1
InteractionMYBL2 interactions

FANCD2 CBX3 GCFC2 SAP130 CREBBP EP300

2.01e-06162476int:MYBL2
InteractionTPX2 interactions

FANCD2 CBX3 PPIG SAP130 NKAPD1 EP300

7.60e-06204476int:TPX2
InteractionZC3H11A interactions

FANCD2 PPIG HNRNPCL1 THOC2 NKAPD1 HNRNPCL2

1.02e-05215476int:ZC3H11A
InteractionCEBPD interactions

FANCD2 NOLC1 CREBBP EP300

1.31e-0562474int:CEBPD
InteractionPHF21A interactions

SFMBT1 APC PSMD1 CHD8 ZFHX4 ZMYND8 S100PBP

1.36e-05343477int:PHF21A
InteractionCDK12 interactions

FANCD2 NOLC1 CBX3 PSMD1 THOC2 EP300

1.43e-05228476int:CDK12
InteractionKLF13 interactions

CREBBP EP300 SH3KBP1

1.54e-0521473int:KLF13
InteractionTP53BP2 interactions

RPGRIP1 CEP152 CREBBP EP300 CNTRL SH3KBP1

1.96e-05241476int:TP53BP2
InteractionHMG20A interactions

FANCD2 SFMBT1 PPIG CREBBP HNRNPCL2 ZMYND8

2.10e-05244476int:HMG20A
InteractionMECP2 interactions

APC NOLC1 CBX3 NRDE2 PPIG HNRNPCL1 THOC2 KDM5A NKAPD1 EP300 ADD2 ZMYND8

2.82e-0512874712int:MECP2
InteractionHOXB7 interactions

GCFC2 CREBBP EP300

2.98e-0526473int:HOXB7
InteractionZNF532 interactions

FANCD2 BTG3 ZMYND8

3.34e-0527473int:ZNF532
InteractionYWHAH interactions

FANCD2 NAV2 APC NOLC1 CEP152 KDM5A CREBBP WNK3 CNTRL SYNE2 PLEKHA3

3.51e-0511024711int:YWHAH
InteractionHNF1A interactions

CBX3 SAP130 CREBBP EP300

3.61e-0580474int:HNF1A
InteractionSETD1A interactions

CBX3 CHD8 RERE CREBBP EP300

4.64e-05170475int:SETD1A
InteractionRBBP4 interactions

FANCD2 CBX3 DYRK4 KDM5A SAP130 CREBBP EP300 ZMYND8

4.81e-05573478int:RBBP4
InteractionGSC interactions

RERE ZFHX4 CREBBP EP300

5.02e-0587474int:GSC
InteractionPPP1R13L interactions

FANCD2 CREBBP EP300 PPP1R12B

5.24e-0588474int:PPP1R13L
InteractionCHD3 interactions

FANCD2 NOLC1 CBX3 ZFHX4 SAP130 CREBBP EP300 HNRNPCL2 ZMYND8

5.37e-05757479int:CHD3
InteractionVPS4A interactions

FANCD2 PSMD1 EP300 SH3KBP1

5.98e-0591474int:VPS4A
InteractionXAB2 interactions

FANCD2 HNRNPCL1 NKAPD1 EP300 HNRNPCL2

7.11e-05186475int:XAB2
InteractionPELP1 interactions

FANCD2 NOLC1 CHD8 CREBBP EP300

7.67e-05189475int:PELP1
InteractionERICH3 interactions

ERICH3 HNRNPCL2

7.94e-056472int:ERICH3
InteractionHOXB2 interactions

CREBBP EP300 SYNE2

8.04e-0536473int:HOXB2
InteractionZMYND8 interactions

SFMBT1 CBX3 RERE KDM5A ZMYND8

8.06e-05191475int:ZMYND8
InteractionIRF7 interactions

FANCD2 CBX3 CREBBP EP300

8.64e-05100474int:IRF7
InteractionCSNK2B interactions

APC NOLC1 CHD8 CREBBP NKAPD1 EP300 SH3KBP1 ZMYND8

8.84e-05625478int:CSNK2B
InteractionTNK2 interactions

PSMD1 EP300 DDHD1 PPP1R12B ADD2

8.89e-05195475int:TNK2
InteractionPHIP interactions

NOLC1 CBX3 RERE ZFHX4 HNRNPCL2

9.32e-05197475int:PHIP
InteractionTRA2A interactions

FANCD2 PPIG HNRNPCL1 NKAPD1 EP300 CNTRL

1.12e-04330476int:TRA2A
InteractionDDX23 interactions

FANCD2 NOLC1 PPIG GCFC2 THOC2 NKAPD1 EP300

1.15e-04480477int:DDX23
InteractionSEC24C interactions

FANCD2 PSMD1 EP300 CNTRL SH3KBP1

1.18e-04207475int:SEC24C
InteractionCNOT3 interactions

BTG3 CEP152 THOC2 CREBBP EP300

1.18e-04207475int:CNOT3
InteractionTFF1 interactions

APC CREBBP EP300

1.19e-0441473int:TFF1
InteractionECPAS interactions

FANCD2 PSMD1 CEP152 THOC2 EP300 PLEKHA3

1.26e-04337476int:ECPAS
InteractionGPATCH1 interactions

RPGRIP1 CEP152 NKAPD1 CNTRL

1.30e-04111474int:GPATCH1
InteractionRCOR1 interactions

SFMBT1 APC PSMD1 CHD8 ZFHX4 ZMYND8 S100PBP

1.37e-04494477int:RCOR1
InteractionHMGXB4 interactions

CBX3 SAP130 CREBBP NKAPD1

1.39e-04113474int:HMGXB4
InteractionTRADD interactions

THOC2 HNRNPCL2 CNTRL SH3KBP1

1.39e-04113474int:TRADD
InteractionLOXHD1 interactions

FANCD2 NOLC1

1.48e-048472int:LOXHD1
InteractionTBXT interactions

ZFHX4 SAP130 CREBBP EP300

1.54e-04116474int:TBXT
InteractionCLK3 interactions

PPIG HNRNPCL1 NKAPD1 HNRNPCL2 SH3KBP1

1.56e-04220475int:CLK3
InteractionMXD1 interactions

CBX3 KDM5A SAP130

1.57e-0445473int:MXD1
InteractionMORF4L1 interactions

NAV2 BTG3 KDM5A EP300 PLEKHA3

1.60e-04221475int:MORF4L1
InteractionRBBP7 interactions

FANCD2 PSMD1 KDM5A SAP130 CREBBP EP300 ZMYND8

1.61e-04507477int:RBBP7
InteractionPIAS1 interactions

FANCD2 NOLC1 CBX3 FHOD3 CREBBP EP300

1.62e-04353476int:PIAS1
InteractionERG interactions

NOLC1 RERE ZFHX4 CREBBP EP300

1.67e-04223475int:ERG
InteractionUSP7 interactions

FANCD2 NAV2 APC TEX15 THOC2 SAP130 CREBBP EP300 WNK3 SH3KBP1 ZMYND8

1.70e-0413134711int:USP7
InteractionHOXB3 interactions

CREBBP EP300

1.90e-049472int:HOXB3
InteractionARGFX interactions

CREBBP EP300

1.90e-049472int:ARGFX
InteractionPTGS2 interactions

APC PSMD1 EP300

1.91e-0448473int:PTGS2
InteractionSAMD1 interactions

SFMBT1 HNRNPCL2 SH3KBP1 ZMYND8

1.92e-04123474int:SAMD1
InteractionRSF1 interactions

FANCD2 FAM133B CBX3 EP300

1.98e-04124474int:RSF1
InteractionHOXB9 interactions

SFMBT1 NOLC1 CREBBP EP300

1.98e-04124474int:HOXB9
InteractionPAX7 interactions

ZFHX4 SAP130 CREBBP EP300

1.98e-04124474int:PAX7
InteractionFOXO3 interactions

FANCD2 CMYA5 CREBBP EP300

1.98e-04124474int:FOXO3
InteractionCDC40 interactions

HNRNPCL1 NKAPD1 EP300 HNRNPCL2

1.98e-04124474int:CDC40
InteractionH3C1 interactions

FANCD2 SFMBT1 NAV2 CBX3 CHD8 KDM5A CREBBP EP300 ZMYND8

2.02e-04901479int:H3C1
InteractionUBTF interactions

FANCD2 CBX3 CREBBP NKAPD1 EP300

2.08e-04234475int:UBTF
InteractionPPIG interactions

CHD8 PPIG HNRNPCL1 NKAPD1

2.18e-04127474int:PPIG
InteractionHAUS8 interactions

RPGRIP1 NRDE2 CEP152 CNTRL

2.18e-04127474int:HAUS8
InteractionMKRN2 interactions

APC HNRNPCL1 NKAPD1 EP300 HNRNPCL2 SYNE2

2.59e-04385476int:MKRN2
InteractionCDC16 interactions

FHOD3 CEP295 CREBBP EP300 SH3KBP1

2.63e-04246475int:CDC16
InteractionIRF5 interactions

CEP152 CREBBP EP300

2.71e-0454473int:IRF5
InteractionISY1 interactions

HNRNPCL1 GCFC2 NKAPD1 HNRNPCL2

2.75e-04135474int:ISY1
InteractionASF1A interactions

CHD8 HNRNPCL1 THOC2 SAP130 EP300

2.78e-04249475int:ASF1A
InteractionFHL2 interactions

APC BTG3 SAP130 CREBBP EP300 WNK3

3.01e-04396476int:FHL2
InteractionNR2C2 interactions

FAM133B NOLC1 CBX3 CHD8 PPIG THOC2 KDM5A SAP130 NKAPD1 ADD2 ZMYND8

3.02e-0414034711int:NR2C2
InteractionDNMT1 interactions

FANCD2 APC CBX3 EP300 SH3KBP1

3.04e-04254475int:DNMT1
InteractionRBPJ interactions

SFMBT1 CBX3 KDM5A CREBBP EP300

3.04e-04254475int:RBPJ
InteractionPSME3 interactions

FANCD2 PSMD1 CHD8 CEP152 CREBBP EP300

3.09e-04398476int:PSME3
InteractionCSNK2A1 interactions

SFMBT1 APC NOLC1 GCFC2 CREBBP NKAPD1 EP300 SH3KBP1 ZMYND8

3.14e-04956479int:CSNK2A1
InteractionHEY1 interactions

APC NOLC1 HNRNPCL1 SYNE2

3.16e-04140474int:HEY1
InteractionCASC3 interactions

APC HNRNPCL1 NKAPD1 EP300

3.33e-04142474int:CASC3
InteractionMAF interactions

PSMD1 CREBBP EP300

3.71e-0460473int:MAF
InteractionNPM1 interactions

FANCD2 CBX3 PSMD1 CHD8 CEP152 TEX15 THOC2 EP300 SYNE2 ZMYND8

3.72e-0412014710int:NPM1
InteractionATRX interactions

FANCD2 CBX3 ZFHX4 CREBBP ZMYND8

3.83e-04267475int:ATRX
InteractionATAD2 interactions

FANCD2 CBX3 HNRNPCL2

3.89e-0461473int:ATAD2
InteractionAMER1 interactions

APC CBX3 CEP295

3.89e-0461473int:AMER1
InteractionSTK17B interactions

FANCD2 NOLC1 NKAPD1

4.08e-0462473int:STK17B
InteractionSRSF7 interactions

FANCD2 PPIG CEP152 THOC2 EP300 SH3KBP1

4.39e-04425476int:SRSF7
InteractionCTNNB1 interactions

FANCD2 APC CBX3 PSMD1 CHD8 CREBBP EP300 PPP1R12B SYNE2

4.66e-041009479int:CTNNB1
InteractionS100P interactions

FAM133B FAM216A EP300 WNK3 ZMYND8

4.68e-04279475int:S100P
InteractionPPIE interactions

PSMD1 HNRNPCL1 GCFC2 THOC2 NKAPD1

4.91e-04282475int:PPIE
InteractionPRPF38A interactions

PPIG HNRNPCL1 NKAPD1 HNRNPCL2

5.36e-04161474int:PRPF38A
InteractionMBD2 interactions

APC SAP130 CREBBP ZMYND8

5.36e-04161474int:MBD2
InteractionKIF23 interactions

APC NOLC1 CBX3 PSMD1 PPIG THOC2 HNRNPCL2 ADD2 SH3KBP1

5.44e-041031479int:KIF23
InteractionKLF2 interactions

CREBBP EP300

5.48e-0415472int:KLF2
InteractionPRPF3 interactions

FANCD2 NAV2 CBX3 NKAPD1 EP300

5.66e-04291475int:PRPF3
InteractionNUP43 interactions

FANCD2 APC CHD8 RERE KDM5A SYNE2 ZMYND8

5.71e-04625477int:NUP43
InteractionFOSL1 interactions

CREBBP EP300 CNTRL

5.83e-0470473int:FOSL1
InteractionMFAP1 interactions

NOLC1 CBX3 PSMD1 CEP295 EP300

6.03e-04295475int:MFAP1
InteractionPTF1A interactions

RPGRIP1 CREBBP

6.26e-0416472int:PTF1A
InteractionMOB1A interactions

FANCD2 THOC2 CREBBP

6.33e-0472473int:MOB1A
InteractionZC3H14 interactions

HNRNPCL1 THOC2 NKAPD1 SH3KBP1

6.43e-04169474int:ZC3H14
InteractionBAZ2A interactions

FANCD2 CBX3 HNRNPCL2

6.59e-0473473int:BAZ2A
InteractionEGR2 interactions

RERE ZFHX4 CREBBP EP300

6.72e-04171474int:EGR2
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.90e-0417222486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.14e-041822291
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

APC PPP1R12B SYTL2

1.32e-03181223694
GeneFamilySterile alpha motif domain containing

SFMBT1 DGKD

5.08e-0388222760
GeneFamilyPHD finger proteins

KDM5A ZMYND8

5.31e-039022288
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DGKD PLEKHA3

2.57e-02206222682
CoexpressionGSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP

SFMBT1 APC RERE EP300 SYNE2

9.93e-06160475M8183
CoexpressionGSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN

SFMBT1 CHD8 ERICH3 PPP1R12B SYNE2

2.77e-05198475M8624
CoexpressionGSE3982_EOSINOPHIL_VS_MAST_CELL_DN

APC PSMD1 FAM216A RERE ZMYND8

2.77e-05198475M5398
CoexpressionGSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP

FAM216A RERE SAP130 DDHD1 ZMYND8

2.84e-05199475M7530
CoexpressionRICKMAN_METASTASIS_UP

FAM133B SFMBT1 PSMD1 PPIG DYRK4 THOC2

3.68e-05350476M9752
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000

NAV2 CHD8 CEP295 THOC2 CREBBP SYNE2

8.67e-07151466gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000

NAV2 CHD8 CEP295 THOC2 CREBBP SYNE2

5.87e-06210466gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000

NAV2 CHD8 THOC2 CREBBP SYNE2

7.96e-06127465gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

FANCD2 SFMBT1 DGKD CEP295 TEX15 KDM5A WNK3 DDHD1 PPP1R12B S100PBP

8.05e-068204610gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

FANCD2 APC NOLC1 FHOD3 PPIG CEP295 GCFC2 THOC2 NKAPD1 WNK3 ADD2 CNTRL SYNE2

8.62e-0614594613facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

NAV2 CHD8 CEP295 THOC2 CREBBP SYNE2

9.87e-06230466gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

FANCD2 APC NOLC1 FHOD3 PPIG CEP295 GCFC2 THOC2 NKAPD1 WNK3 CNTRL SYNE2

1.04e-0512574612facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

FANCD2 SFMBT1 APC FHOD3 PPIG CEP295 GCFC2 KDM5A WNK3 CNTRL SYNE2

1.21e-0510604611facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

NAV2 CHD8 CEP295 THOC2 SYNE2

1.79e-05150465gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

NAV2 CHD8 CEP295 THOC2 CREBBP SYNE2

2.71e-05275466gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

FANCD2 SFMBT1 APC FHOD3 PPIG CEP295 GCFC2 KDM5A WNK3 ADD2 CNTRL SYNE2

3.38e-0514144612facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

APC PPIG CEP295 KDM5A SAP130 EP300 WNK3 SYNE2

3.70e-05595468Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

NAV2 DGKD CHD8 CEP295 TEX15 THOC2 KDM5A CREBBP SYNE2

3.70e-05778469gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500

CHD8 CEP295 CREBBP SYNE2

8.45e-05107464gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

NAV2 DGKD CHD8 CEP295 TEX15 THOC2 KDM5A SYNE2

2.34e-04776468gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_500

CHD8 CEP295 SYNE2

4.14e-0467463gudmap_developingGonad_e18.5_epididymis_500_k3
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NAV2 ERICH3 RERE ZFHX4 SYTL2 ZMYND8

3.77e-081824767b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

APC PPIG CEP295 SAP130 CREBBP EP300

4.29e-0818647603db813598b67b1e08f759758a1c2023396921fa
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

NRDE2 PPIG CEP295 CEP152 THOC2 KDM5A

6.04e-081974760fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BTG3 FAM216A CEP295 CEP152 CNTRL

1.87e-06194475dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FANCD2 NAV2 CEP152 CNTRL SYNE2

2.12e-06199475be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM133B DGKD RERE CREBBP

3.02e-05169474c3a6179a64589a370108fea809b157839347759c
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKD DYRK4 KDM5A PPP1R12B

3.09e-051704743ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 NAV2 CEP152 DYRK4

3.16e-05171474c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APC EP300 CNTRL SH3KBP1

4.21e-051844741154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NAV2 DGKD RERE ZMYND8

4.48e-051874747e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NAV2 DGKD RERE ZMYND8

4.58e-05188474b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DGKD FHOD3 CMYA5 PPP1R12B

5.07e-05193474dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

PSMD1 PPIG CNTRL SYNE2

5.60e-0519847476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(11)_FOXN4+|World / shred by cell type by condition

BTG3 FAM216A CEP152 CNTRL

5.60e-05198474516b1acdf997dd8debc3dca066519366e507b414
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FAM133B DDHD1 SYNE2 SYTL2

5.71e-05199474f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

PPIG THOC2 CNTRL SYNE2

5.71e-05199474fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAV2 CEP152 CNTRL SYNE2

5.71e-0519947498575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CMYA5 ZFHX4 PPP1R12B SYTL2

5.71e-0519947438cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

PPIG THOC2 PPP1R12B SYNE2

5.71e-05199474a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

BTG3 CEP152 ZFHX4 SYNE2

5.82e-052004744923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

BTG3 CEP152 ZFHX4 SYNE2

5.82e-05200474971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CEP152 CNTRL SYNE2

5.82e-052004740d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

BTG3 CEP152 ZFHX4 SYNE2

5.82e-05200474dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CEP152 CNTRL SYNE2

5.82e-052004740675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CMYA5 ZFHX4 PPP1R12B SYTL2

5.82e-0520047409537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-dn_T|Multiple_Sclerosis / Disease, condition lineage and cell class

BTG3 NRDE2 PPP1R12B SYNE2

5.82e-052004741aa298dd7172e023adf569c32e49f69fa8d9c7ff
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

2.89e-041224731cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

APC PPIG SYNE2

4.15e-04138473817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellLPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFMBT1 CHD8 CEP152

4.51e-04142473b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM133B DGKD RERE

5.09e-04148473dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTG3 GCFC2 PPP1R12B

6.98e-04165473475905d608fac628960188ae4a18010b8097417e
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCFC2 PPP1R12B PLEKHA3

7.35e-04168473de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP152 SAP130 WNK3

7.35e-04168473a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CBX3 CEP152 MUCL3

7.35e-041684734e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CBX3 CEP152 MUCL3

7.35e-04168473ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCellmild_COVID-19_(asymptomatic)-gd_T|World / disease group, cell group and cell class (v2)

WNK3 SYNE2 SYTL2

8.00e-04173473b6615ff02f5017d7150b1e33b53f8c7a26081a0d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DGKD RERE CNTRL

8.00e-04173473d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT|blood / Manually curated celltypes from each tissue

FHOD3 SYNE2 SYTL2

8.27e-04175473b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

CHD8 CREBBP ZMYND8

8.27e-04175473c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 TEX15 MUCL3

8.55e-04177473f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTG3 CNTRL SYNE2

8.69e-0417847301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BTG3 CEP152 CNTRL

8.83e-04179473d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BTG3 CEP152 CNTRL

8.83e-04179473e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SFMBT1 CBX3 CEP152

8.83e-04179473ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ERICH3 ZFHX4 SYTL2

8.83e-0417947314fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 CBX3 SH3KBP1

8.97e-04180473de87503d9caac3ebc80ab8090c1a9ee5a925b2a0
ToppCellnormal-na-Lymphocytic_NK-T_mait-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

FHOD3 SYNE2 SYTL2

8.97e-04180473e66a8a61b3576ac37de7c559d16d4ed4f7a2fc78
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAV2 NRDE2 SYNE2

9.12e-041814733f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAV2 NRDE2 SYNE2

9.12e-04181473330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellRV|World / Chamber and Cluster_Paper

FHOD3 CMYA5 ZMYND8

9.12e-04181473bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

DGKD FHOD3 CMYA5

9.26e-04182473287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EP300 CNTRL SH3KBP1

9.26e-04182473f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

DGKD FHOD3 CMYA5

9.41e-041834732902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

DGKD SYNE2 SYTL2

9.41e-04183473f593a89b0aa8fffdfa403769916facfd30358521
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

FANCD2 DDHD1 S100PBP

9.41e-04183473f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FHOD3 CMYA5 PPP1R12B

9.71e-04185473549eeb521c3985bff396ea0f202db21822efa51f
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EP300 CNTRL SH3KBP1

9.71e-041854737adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DGKD TEX15 HNRNPCL2

9.71e-041854736e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

CEP295 WNK3 SYNE2

9.71e-04185473857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

BTG3 FAM216A CEP152

9.71e-041854739a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

9.71e-041854736baccb26f999145e51b91d94315bf8d4655bef31
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

NAV2 FHOD3 WNK3

9.71e-04185473c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

ERICH3 SYNE2 SYTL2

9.86e-04186473ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP295 CNTRL SYNE2

9.86e-041864734ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUCL3 SYNE2 SYTL2

9.86e-041864738eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

DGKD RERE ZMYND8

9.86e-04186473de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DGKD RERE ZMYND8

9.86e-041864730b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP295 CNTRL SYNE2

9.86e-0418647315ab6666748a641226e42e6ca6eeaf186a501c95
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPIG CREBBP SYNE2

1.00e-03187473663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 PLEKHA3 SYTL2

1.00e-03187473cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCellmild_COVID-19-CD4+_CTL|mild_COVID-19 / disease group, cell group and cell class (v2)

BTG3 SYNE2 SYTL2

1.00e-0318747349196d07e4716c87d33229a4569bdb6b4613b3eb
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAV2 BTG3 DGKD

1.02e-031884732b8d70f761eda5509f21845a87cdb3602a639dd7
ToppCell3'_v3-GI_small-bowel|World / Manually curated celltypes from each tissue

FAM133B BTG3 SYTL2

1.02e-03188473822c6abaf7bcd6721269bdbd1f2b286ccf0aec1a
ToppCell3'_v3-Lung-Lymphocytic_T_CD8-Tem/emra_CD8|Lung / Manually curated celltypes from each tissue

FAM133B SYNE2 SYTL2

1.03e-03189473f43bb9db7bb2d19c9849cd3ed892fe3e09e7dfe2
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

NAV2 FHOD3 ZFHX4

1.03e-0318947346c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellASK452-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SYNE2 SYTL2 S100PBP

1.03e-03189473f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

1.03e-031894739c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

1.03e-031894735e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FANCD2 NAV2 CEP152

1.03e-031894731e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DDHD1 SYNE2 SYTL2

1.05e-031904731f890be1ac8613a098b271945f25a58c3c2530ab
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BTG3 CEP295 CEP152

1.05e-03190473250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

DGKD FHOD3 CMYA5

1.05e-0319047393c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BTG3 CEP295 CEP152

1.05e-031904737be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

1.05e-03190473de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Th17_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BTG3 SH3KBP1 SYTL2

1.05e-03190473693b223f6b94a46d935fbcb02d7a27340ce43154
ToppCellASK454-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SFMBT1 ERICH3 SYTL2

1.05e-031904735cea6480f08253d7adf484e511d3fdfa96641268
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERICH3 ZFHX4 SYNE2

1.05e-031904738a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BTG3 CEP295 CEP152

1.05e-031904730adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DDHD1 SYNE2 SYTL2

1.05e-03190473d7cecf88451f736f8f3f6f4644504cf22846cd6e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BTG3 CEP295 CEP152

1.05e-0319047305455775845f4ded5c27e7b83242078d23162aaf
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FANCD2 NAV2 CEP152

1.05e-03190473e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FANCD2 CEP295 CEP152

1.05e-03190473d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

SFMBT1 SYNE2 SYTL2

1.05e-03190473d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

1.05e-03190473fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_CTL-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BTG3 SYNE2 SYTL2

1.06e-031914737ad9b7a77d8a803011306a7f716f62b19b7dc556
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

1.06e-0319147325f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_CTL|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BTG3 SYNE2 SYTL2

1.06e-03191473913cbdd370e0bcc57038dc4c78a4b6d7ac420b5d
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

FAM216A CEP295 CEP152

1.06e-0319147337cf121e6e80760c8519075b7845b9029958a988
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

FHOD3 CMYA5 PPP1R12B

1.06e-031914735d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_CTL|COVID-19_Severe / Disease group, lineage and cell class

BTG3 SYNE2 SYTL2

1.06e-03191473ca138cc2224b32dd08cf98ead00188bcfb1a9b69
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; HL60; HT_HG-U133A

APC NRDE2 RERE TEX15 PPP1R12B SYTL2

3.20e-061984762197_UP
DiseaseMenke-Hennekam syndrome

CREBBP EP300

2.38e-062462cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

2.38e-062462DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

2.38e-062462cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

2.38e-062462C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

2.38e-062462180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

2.38e-062462cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

2.38e-062462DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

2.38e-062462C0035934
DiseaseBenign tumor of pancreas

APC EP300

1.83e-0413462C0347284
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5A ZMYND8

2.81e-0416462DOID:0050888 (implicated_via_orthology)
DiseasePancreatic carcinoma

APC EP300

4.00e-0419462C0235974
DiseaseColorectal cancer

APC EP300

8.14e-0427462cv:C0346629
DiseaseCOLORECTAL CANCER

APC EP300

8.14e-0427462114500
DiseaseNeoplasm of the large intestine

APC EP300

8.14e-0427462cv:C0009404
Diseaseplasma betaine measurement

NOLC1 KDM5A

1.29e-0334462EFO_0007787
DiseaseMental Retardation, Psychosocial

APC CHD8 KDM5A

1.34e-03139463C0025363
DiseaseProfound Mental Retardation

APC CHD8 KDM5A

1.34e-03139463C0020796
DiseaseMental deficiency

APC CHD8 KDM5A

1.34e-03139463C0917816

Protein segments in the cluster

PeptideGeneStartEntry
EEDKQDMKTASSTSS

ERICH3

571

Q5RHP9
KMESTETEERSTELK

EP300

1006

Q09472
TTSAEKDKDKREDTL

CABS1

271

Q96KC9
SSSSTDESEDEKEEK

CHD8

2091

Q9HCK8
KDEKSIEVETKTDTS

CEP152

586

O94986
ERESEESKLETSKVT

CNTRL

1956

Q7Z7A1
RKSLSDSESDDSKSK

CBX3

91

Q13185
EERKKEESTAASETT

CREBBP

1561

Q92793
SEEESSSSEEEKTKK

NOLC1

426

Q14978
SSSEEEEEKTSKSAV

NOLC1

476

Q14978
SSSDSSEDKDEKISE

MSL3P1

56

P0C860
EEEQSSSSMKKDETH

HNRNPCL1

221

O60812
EEEQSSSSMKKDETH

HNRNPCL2

221

B2RXH8
SLSSTSEDSEKDEKD

KIAA1109

3721

Q2LD37
SSSRSETDTDSEKDK

NRDE2

106

Q9H7Z3
DMKDTASVKSSSSLE

KDM5A

1356

P29375
SSDSESATEEKSKKR

PPIG

216

Q13427
ADEITKETTEKTKDS

DYRK4

441

Q9NR20
KSSESSMSETESDSK

FAM133B

141

Q5BKY9
SMSETESDSKDSLKK

FAM133B

146

Q5BKY9
FMDSSVEDSKKESSS

GCFC2

531

P16383
KTKEEISTDSETDLS

CMYA5

3026

Q8N3K9
SSSSSTLEREEKEDK

FHOD3

631

Q2V2M9
TESSEESEVMAKKCS

DGKD

526

Q16760
TQSSETSKDSMEDEK

DDHD1

771

Q8NEL9
SSDDSESHMSEEKKE

FAM216A

236

Q8WUB2
SEHMDDSKQESTTSK

CEP295

1986

Q9C0D2
EKETSAEKSKESGST

ZMYND8

1106

Q9ULU4
DKDETDSSKDTEKLS

S100PBP

161

Q96BU1
EDKESLTEDASKTRK

FANCD2

11

Q9BXW9
SEKTEDSRTTVASDK

MUCL3

246

Q3MIW9
TSKEDELSESKEKST

SYTL2

191

Q9HCH5
DTKDSSKISSEEEKA

RPGRIP1

946

Q96KN7
SKEEKATVEFSTDMS

SYNE2

691

Q8WXH0
SDVSDESDKSTSGKK

NAV2

1036

Q8IVL1
DSSKTEMDSRTKSKD

SH3KBP1

256

Q96B97
EKDSDSMETEEKTSS

PSMD1

291

Q99460
SSTKETERKETKAEE

SIL1

46

Q9H173
SDTEEADRTSSKKTK

RERE

656

Q9P2R6
SSSSDEETSKEMEVK

BTG3

146

Q14201
TSADTDVDTSKDKTE

ADD2

671

P35612
ASSESSEKAKSEDEK

APC

2576

P25054
KSKKEATDITADSSS

NKAPD1

171

Q6ZUT1
SSSEESEERDTKKTK

NKAPD1

236

Q6ZUT1
ETKEDKSTATESTKE

ZFHX4

3316

Q86UP3
ASKSDESSTEETDKS

THOC2

1216

Q8NI27
METNSTDDEKSTAKS

SAP130

851

Q9H0E3
TDTRTKKEKEISETS

PLEKHA3

96

Q9HB20
QEESEMSEKKSCSSS

SFMBT1

726

Q9UHJ3
EITKSSTSTIKDKDE

TEX15

306

Q9BXT5
KSVEMTEDDKVAESS

WNK3

61

Q9BYP7
KSQEMEEENKESSSS

PPP1R12B

346

O60237