Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS10 ADAMTS19 BMP1 CLCA4 ADAMTS20 ADAMTS5 ADAMTSL2	5.24e-07	120	80	7	GO:0004222
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FRAS1 LAMA2 LAMA3 NTN1 LTBP1 BMPER FBN3	1.04e-05	188	80	7	GO:0005201
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS10 ADAMTS19 BMP1 CLCA4 ADAMTS20 ADAMTS5 ADAMTSL2	1.56e-05	200	80	7	GO:0008237
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	STAB2 LRP1 LRP1B	3.34e-05	16	80	3	GO:0005041
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS10 ERVK-6 ADAMTS19 BMP1 CLCA4 ADAMTS20 ADAMTS5 ADAMTSL2 USP33	5.50e-05	430	80	9	GO:0004175
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	STAB2 LRP1 LRP1B	7.82e-05	21	80	3	GO:0030228
GeneOntologyMolecularFunction	scavenger receptor activity	STAB2 LRP1 CD163	1.69e-04	27	80	3	GO:0005044
GeneOntologyMolecularFunction	extracellular matrix binding	ZAN LTBP1 ADAMTS5 ADAMTSL2	2.11e-04	73	80	4	GO:0050840
GeneOntologyMolecularFunction	microfibril binding	LTBP1 ADAMTSL2	2.35e-04	6	80	2	GO:0050436
GeneOntologyMolecularFunction	cargo receptor activity	STAB2 LRP1 LRP1B CD163	3.78e-04	85	80	4	GO:0038024
GeneOntologyMolecularFunction	peptidase activity	ADAMTS10 ERVK-6 ADAMTS19 BMP1 CLCA4 ADAMTS20 ADAMTS5 ADAMTSL2 USP33	1.20e-03	654	80	9	GO:0008233
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTS10 ADAMTS19 BMP1 SPINT2 NR2E1 LRP1 LAMA2 ADAMTS20 ADAMTS5 ADAMTSL2	2.45e-06	377	82	10	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTS10 ADAMTS19 BMP1 SPINT2 NR2E1 LRP1 LAMA2 ADAMTS20 ADAMTS5 ADAMTSL2	2.51e-06	378	82	10	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTS10 ADAMTS19 BMP1 SPINT2 NR2E1 LRP1 LAMA2 ADAMTS20 ADAMTS5 ADAMTSL2	2.57e-06	379	82	10	GO:0045229
GeneOntologyCellularComponent	extracellular matrix	ADAMTS10 ADAMTS19 BMP1 FRAS1 ZAN OTOGL LAMA2 LAMA3 ADAMTS20 NTN1 CFP LTBP1 ADAMTS5 BMPER FBN3 ADAMTSL2	3.73e-09	656	81	16	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS10 ADAMTS19 BMP1 FRAS1 ZAN OTOGL LAMA2 LAMA3 ADAMTS20 NTN1 CFP LTBP1 ADAMTS5 BMPER FBN3 ADAMTSL2	3.89e-09	658	81	16	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS10 BMP1 FRAS1 LAMA2 LAMA3 ADAMTS20 NTN1 CFP LTBP1 ADAMTS5 BMPER	6.12e-06	530	81	11	GO:0062023
GeneOntologyCellularComponent	microfibril	ADAMTS10 LTBP1 FBN3	1.56e-05	13	81	3	GO:0001527
GeneOntologyCellularComponent	Cul5-RING ubiquitin ligase complex	KLHDC1 ASB4	6.54e-04	10	81	2	GO:0031466
GeneOntologyCellularComponent	basement membrane	FRAS1 LAMA2 LAMA3 NTN1	1.30e-03	122	81	4	GO:0005604
Domain	EGF	BMP1 ITGBL1 FRAS1 BRINP3 STAB2 ZAN TENM3 LRP1 LAMA2 LAMA3 LTBP1 LRP1B FBN3	2.94e-11	235	82	13	SM00181
Domain	EGF_2	EPHB2 BMP1 ITGBL1 STAB2 ZAN TENM3 LRP1 LAMA2 LAMA3 NTN1 LTBP1 LRP1B FBN3	1.31e-10	265	82	13	PS01186
Domain	EGF-like_dom	BMP1 ITGBL1 FRAS1 STAB2 ZAN TENM3 LRP1 LAMA2 LAMA3 LTBP1 LRP1B FBN3	8.78e-10	249	82	12	IPR000742
Domain	EGF_1	BMP1 ITGBL1 STAB2 ZAN TENM3 LRP1 LAMA2 LAMA3 NTN1 LTBP1 LRP1B FBN3	1.15e-09	255	82	12	PS00022
Domain	Growth_fac_rcpt_	EPHB2 BMP1 FRAS1 BRINP3 STAB2 LRP1 LAMA3 LTBP1 LRP1B FBN3	1.58e-09	156	82	10	IPR009030
Domain	TSP_1	ADAMTS10 ADAMTS19 ISM1 ADAMTS20 CFP ADAMTS5 ADAMTSL2	1.10e-08	63	82	7	PF00090
Domain	TSP1	ADAMTS10 ADAMTS19 ISM1 ADAMTS20 CFP ADAMTS5 ADAMTSL2	1.37e-08	65	82	7	SM00209
Domain	TSP1_rpt	ADAMTS10 ADAMTS19 ISM1 ADAMTS20 CFP ADAMTS5 ADAMTSL2	1.37e-08	65	82	7	IPR000884
Domain	TSP1	ADAMTS10 ADAMTS19 ISM1 ADAMTS20 CFP ADAMTS5 ADAMTSL2	1.37e-08	65	82	7	PS50092
Domain	EGF-like_CS	BMP1 STAB2 ZAN TENM3 LRP1 LAMA2 LAMA3 NTN1 LTBP1 LRP1B FBN3	1.88e-08	261	82	11	IPR013032
Domain	ADAM_spacer1	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5 ADAMTSL2	4.56e-08	23	82	5	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5 ADAMTSL2	4.56e-08	23	82	5	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5 ADAMTSL2	5.74e-08	24	82	5	IPR013273
Domain	EGF	BMP1 STAB2 ZAN LRP1 LTBP1 LRP1B FBN3	1.34e-06	126	82	7	PF00008
Domain	cEGF	LRP1 LTBP1 LRP1B FBN3	4.79e-06	26	82	4	IPR026823
Domain	cEGF	LRP1 LTBP1 LRP1B FBN3	4.79e-06	26	82	4	PF12662
Domain	Retrov_capsid_C	ADAMTS10 ERVK-6 ZNF394 ZNF174 ERVK-5	5.99e-06	59	82	5	IPR008916
Domain	EGF_LAM_2	STAB2 LAMA2 LAMA3 NTN1	8.67e-06	30	82	4	PS50027
Domain	EGF_LAM_1	STAB2 LAMA2 LAMA3 NTN1	8.67e-06	30	82	4	PS01248
Domain	EGF_3	BMP1 STAB2 ZAN TENM3 LRP1 LTBP1 LRP1B FBN3	8.92e-06	235	82	8	PS50026
Domain	EGF_CA	BMP1 STAB2 LRP1 LTBP1 LRP1B FBN3	1.60e-05	122	82	6	SM00179
Domain	EGF_Lam	STAB2 LAMA2 LAMA3 NTN1	1.63e-05	35	82	4	SM00180
Domain	EGF-like_Ca-bd_dom	BMP1 STAB2 LRP1 LTBP1 LRP1B FBN3	1.76e-05	124	82	6	IPR001881
Domain	DUF5050	LRP1 LRP1B	1.90e-05	2	82	2	IPR032485
Domain	DUF5050	LRP1 LRP1B	1.90e-05	2	82	2	PF16472
Domain	Laminin_EGF	STAB2 LAMA2 LAMA3 NTN1	2.27e-05	38	82	4	IPR002049
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.53e-05	39	82	4	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.53e-05	39	82	4	PF01562
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.80e-05	40	82	4	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.80e-05	40	82	4	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.80e-05	40	82	4	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.80e-05	40	82	4	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	2.80e-05	40	82	4	IPR001590
Domain	MetalloPept_cat_dom	ADAMTS10 ADAMTS19 BMP1 ADAMTS20 ADAMTS5	2.84e-05	81	82	5	IPR024079
Domain	-	ADAMTS10 ADAMTS19 BMP1 ADAMTS20 ADAMTS5	2.84e-05	81	82	5	3.40.390.10
Domain	PLAC	ADAMTS10 ADAMTS19 ADAMTSL2	2.87e-05	14	82	3	PF08686
Domain	Disintegrin_dom	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	3.09e-05	41	82	4	IPR001762
Domain	EGF_CA	BMP1 LRP1 LTBP1 LRP1B FBN3	3.80e-05	86	82	5	PF07645
Domain	Laminin_N	LAMA2 LAMA3 NTN1	4.38e-05	16	82	3	IPR008211
Domain	LAMININ_NTER	LAMA2 LAMA3 NTN1	4.38e-05	16	82	3	PS51117
Domain	Laminin_N	LAMA2 LAMA3 NTN1	4.38e-05	16	82	3	PF00055
Domain	LamNT	LAMA2 LAMA3 NTN1	4.38e-05	16	82	3	SM00136
Domain	EGF_Ca-bd_CS	BMP1 LRP1 LTBP1 LRP1B FBN3	6.77e-05	97	82	5	IPR018097
Domain	ZINC_PROTEASE	ADAMTS10 ADAMTS19 BMP1 ADAMTS20 ADAMTS5	7.11e-05	98	82	5	PS00142
Domain	EGF_CA	BMP1 LRP1 LTBP1 LRP1B FBN3	7.47e-05	99	82	5	PS01187
Domain	PLAC	ADAMTS10 ADAMTS19 ADAMTSL2	7.51e-05	19	82	3	PS50900
Domain	PLAC	ADAMTS10 ADAMTS19 ADAMTSL2	7.51e-05	19	82	3	IPR010909
Domain	ASX_HYDROXYL	BMP1 LRP1 LTBP1 LRP1B FBN3	7.83e-05	100	82	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	BMP1 LRP1 LTBP1 LRP1B FBN3	1.03e-04	106	82	5	IPR000152
Domain	zf-CCHC	ERVK-6 ZCCHC14 ERVK-5	1.36e-04	23	82	3	PF00098
Domain	EGF_extracell	ITGBL1 STAB2 TENM3 LRP1B	1.40e-04	60	82	4	IPR013111
Domain	EGF_2	ITGBL1 STAB2 TENM3 LRP1B	1.40e-04	60	82	4	PF07974
Domain	Laminin_aI	LAMA2 LAMA3	1.89e-04	5	82	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA3	1.89e-04	5	82	2	PF06008
Domain	Laminin_II	LAMA2 LAMA3	1.89e-04	5	82	2	PF06009
Domain	Laminin_domII	LAMA2 LAMA3	1.89e-04	5	82	2	IPR010307
Domain	TB	LTBP1 FBN3	3.94e-04	7	82	2	PF00683
Domain	Laminin_EGF	LAMA2 LAMA3 NTN1	4.82e-04	35	82	3	PF00053
Domain	ZF_CCHC	ERVK-6 ZCCHC14 ERVK-5	4.82e-04	35	82	3	PS50158
Domain	LAMININ_IVA	LAMA2 LAMA3	5.24e-04	8	82	2	PS51115
Domain	Laminin_B	LAMA2 LAMA3	5.24e-04	8	82	2	PF00052
Domain	-	LTBP1 FBN3	5.24e-04	8	82	2	3.90.290.10
Domain	LamB	LAMA2 LAMA3	5.24e-04	8	82	2	SM00281
Domain	Laminin_IV	LAMA2 LAMA3	5.24e-04	8	82	2	IPR000034
Domain	VWFC_1	FRAS1 ZAN BMPER	5.25e-04	36	82	3	PS01208
Domain	VWC	FRAS1 ZAN BMPER	6.16e-04	38	82	3	SM00214
Domain	VWFC_2	FRAS1 ZAN BMPER	6.16e-04	38	82	3	PS50184
Domain	-	TENM3 LRP1 LRP1B	6.65e-04	39	82	3	2.120.10.30
Domain	TB	LTBP1 FBN3	6.72e-04	9	82	2	PS51364
Domain	TB_dom	LTBP1 FBN3	6.72e-04	9	82	2	IPR017878
Domain	LDLR_class-A_CS	LRP1 LRP1B LDLRAD4	7.17e-04	40	82	3	IPR023415
Domain	VWF_dom	FRAS1 ZAN BMPER	8.28e-04	42	82	3	IPR001007
Domain	Ldl_recept_a	LRP1 LRP1B LDLRAD4	1.01e-03	45	82	3	PF00057
Domain	-	LRP1 LRP1B LDLRAD4	1.08e-03	46	82	3	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	TENM3 LRP1 LRP1B	1.08e-03	46	82	3	IPR011042
Domain	TIL	ZAN BMPER	1.22e-03	12	82	2	PF01826
Domain	C8	ZAN BMPER	1.22e-03	12	82	2	PF08742
Domain	LDLRA_1	LRP1 LRP1B LDLRAD4	1.22e-03	48	82	3	PS01209
Domain	LDLRA_2	LRP1 LRP1B LDLRAD4	1.30e-03	49	82	3	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1 LRP1B LDLRAD4	1.30e-03	49	82	3	IPR002172
Domain	LDLa	LRP1 LRP1B LDLRAD4	1.30e-03	49	82	3	SM00192
Domain	Unchr_dom_Cys-rich	ZAN BMPER	1.44e-03	13	82	2	IPR014853
Domain	C8	ZAN BMPER	1.44e-03	13	82	2	SM00832
Domain	TIL_dom	ZAN BMPER	1.67e-03	14	82	2	IPR002919
Domain	Ldl_recept_b	LRP1 LRP1B	1.67e-03	14	82	2	PF00058
Domain	LDLRB	LRP1 LRP1B	1.67e-03	14	82	2	PS51120
Domain	ZnF_C2HC	ERVK-6 ZCCHC14 ERVK-5	1.82e-03	55	82	3	SM00343
Domain	Znf_CCHC	ERVK-6 ZCCHC14 ERVK-5	1.82e-03	55	82	3	IPR001878
Domain	LY	LRP1 LRP1B	1.93e-03	15	82	2	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP1B	1.93e-03	15	82	2	IPR000033
Domain	VWD	ZAN BMPER	2.20e-03	16	82	2	SM00216
Domain	VWF_type-D	ZAN BMPER	2.20e-03	16	82	2	IPR001846
Domain	VWFD	ZAN BMPER	2.20e-03	16	82	2	PS51233
Domain	VWD	ZAN BMPER	2.20e-03	16	82	2	PF00094
Domain	-	ZNF133 ZNF32 ZNF394 ZNF257 ZNF174 ZNF648 ZNF683 ZNF229 ZNF519	2.89e-03	679	82	9	3.30.160.60
Domain	VWC_out	FRAS1 ZAN	3.10e-03	19	82	2	SM00215
Domain	zf-C2H2	ZNF133 ZNF32 ZNF394 ZNF257 ZNF174 ZNF648 ZNF683 ZNF229 ZNF519	3.31e-03	693	82	9	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF133 ZNF32 ZNF394 ZNF257 ZNF174 ZNF648 ZNF683 ZNF229 ZNF519	3.34e-03	694	82	9	IPR013087
Domain	-	EPHB2 LAMA2 NTN1	4.07e-03	73	82	3	2.60.120.260
Domain	Reg_chr_condens	MARVELD1 NEK9	4.15e-03	22	82	2	IPR000408
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTS19 ADAMTS20 CFP ADAMTS5 ADAMTSL2	1.49e-08	39	61	6	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTS19 ADAMTS20 CFP ADAMTS5 ADAMTSL2	1.49e-08	39	61	6	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 ADAMTS19 ADAMTS20 CFP ADAMTS5 ADAMTSL2	4.53e-07	68	61	6	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 ADAMTS19 ADAMTS20 CFP ADAMTS5 ADAMTSL2	7.31e-06	109	61	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 ADAMTS19 ADAMTS20 CFP ADAMTS5 ADAMTSL2	8.12e-06	111	61	6	M27416
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS10 ADAMTS19 ADAMTS20 CFP ADAMTS5 ADAMTSL2	3.44e-05	143	61	6	M27275
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	BMP1 LAMA2 LAMA3 LTBP1 ADAMTS5 PLOD2 FBN3	3.01e-04	300	61	7	M610
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 ADAMTS19 ISM1 ADAMTS20 CFP ADAMTS5 ADAMTSL2	5.93e-10	75	83	7	20637190
Pubmed	Molecular architecture of the developing mouse brain.	EPHB2 WNT7B ISM1 NR2E1 NTN1 SIM1	7.92e-07	132	83	6	34321664
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS10 ADAMTS20 ADAMTS5	2.84e-06	12	83	3	25770910
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FRAS1 LAMA2 LAMA3 NTN1 LTBP1 BMPER	3.11e-06	167	83	6	22159717
Pubmed	Macromolecular organization of basement membranes.	LAMA2 LAMA3	5.63e-06	2	83	2	8939648
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1 LRP1B	5.63e-06	2	83	2	15963947
Pubmed	Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1.	LRP1 ADAMTS5	5.63e-06	2	83	2	28306378
Pubmed	Homozygosity mapping of a Weill-Marchesani syndrome locus to chromosome 19p13.3-p13.2.	ADAMTS10 FBN3	5.63e-06	2	83	2	11941487
Pubmed	LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage.	LRP1 ADAMTS5	5.63e-06	2	83	2	23064555
Pubmed	LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation.	LRP1 BMPER	5.63e-06	2	83	2	28596374
Pubmed	A genomic atlas of mouse hypothalamic development.	EPHB2 NEXMIF WNT7B LTBP1 BMPER SIM1	1.01e-05	205	83	6	20436479
Pubmed	Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.	LRP1 ADAMTS5	1.69e-05	3	83	2	24474687
Pubmed	A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.	ADAMTS20 ADAMTS5	1.69e-05	3	83	2	24753090
Pubmed	ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation.	LTBP1 ADAMTSL2	1.69e-05	3	83	2	18677313
Pubmed	Soluble Receptors Affecting Stroke Outcomes: Potential Biomarkers and Therapeutic Tools.	LRP1 CD163	1.69e-05	3	83	2	33498620
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	BMP1 ITGBL1 LAMA2 LTBP1 ADAMTS5 BMPER	2.95e-05	248	83	6	24006456
Pubmed	Effects of Emx2 inactivation on the gene expression profile of neural precursors.	WNT7B NTN1	3.37e-05	4	83	2	16420441
Pubmed	The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.	LAMA2 DYSF	3.37e-05	4	83	2	23274062
Pubmed	Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 gamma 2 chain.	BMP1 LAMA3	3.37e-05	4	83	2	10806203
Pubmed	Elevated Expression of Moesin in Muscular Dystrophies.	LAMA2 DYSF	3.37e-05	4	83	2	28082118
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-5	3.37e-05	4	83	2	7983737
Pubmed	MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1.	LRP1 ADAMTS5	3.37e-05	4	83	2	27084377
Pubmed	BMP1-like proteinases are essential to the structure and wound healing of skin.	BMP1 LAMA2	3.37e-05	4	83	2	27363389
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	FRAS1 LAMA2 LAMA3 NTN1	3.95e-05	79	83	4	18757743
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	ZCCHC14 LTBP1 LDLRAD4	4.11e-05	28	83	3	33953184
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	FRAS1 LAMA2 LAMA3	4.58e-05	29	83	3	22613833
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA2 LAMA3	5.60e-05	5	83	2	11969289
Pubmed	Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.	ADAMTS10 ADAMTSL2	5.60e-05	5	83	2	29758265
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-5	5.60e-05	5	83	2	11401426
Pubmed	Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.	LAMA2 DYSF	5.60e-05	5	83	2	22427904
Pubmed	Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.	LAMA2 LAMA3	5.60e-05	5	83	2	9415429
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA2 LAMA3	5.60e-05	5	83	2	11829758
Pubmed	Differential expression of laminin alpha chains during murine tooth development.	LAMA2 LAMA3	5.60e-05	5	83	2	9389447
Pubmed	Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling.	WNT7B NTN1	8.39e-05	6	83	2	14671310
Pubmed	HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.	LAMA2 LAMA3	8.39e-05	6	83	2	9597096
Pubmed	BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein.	BMP1 LTBP1	8.39e-05	6	83	2	17015622
Pubmed	EphB2-mediated interactions are essential for proper migration of T cell progenitors during fetal thymus colonization.	EPHB2 CCL21	1.17e-04	7	83	2	20504947
Pubmed	Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.	LAMA2 LAMA3	1.17e-04	7	83	2	9004048
Pubmed	Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene.	EPHB2 NTN1	1.17e-04	7	83	2	15044550
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	STAB2 TENM3 PRKD1 LRP1B RYR2	1.18e-04	199	83	5	23382691
Pubmed	Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.	ADAMTS20 ADAMTS5	1.56e-04	8	83	2	21041365
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA2 LAMA3	1.56e-04	8	83	2	9852162
Pubmed	Eph/ephrin-B-mediated cell-to-cell interactions govern MTS20(+) thymic epithelial cell development.	EPHB2 CCL21	1.56e-04	8	83	2	27060907
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA2 LAMA3	1.56e-04	8	83	2	8872465
Pubmed	Genetic modifiers of muscular dystrophy: implications for therapy.	LAMA2 DYSF	2.00e-04	9	83	2	16916601
Pubmed	Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina.	EPHB2 NTN1	2.00e-04	9	83	2	10683176
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMA3	2.50e-04	10	83	2	9034910
Pubmed	AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.	LAMA2 RYR2	2.50e-04	10	83	2	18434328
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS10 ADAMTS5	2.50e-04	10	83	2	11167130
Pubmed	Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space.	EPHB2 NTN1	2.50e-04	10	83	2	20652952
Pubmed	Competition is a driving force in topographic mapping.	EPHB2 TENM3	3.05e-04	11	83	2	22065784
Pubmed	Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.	ADAMTS19 ADAMTS5	3.05e-04	11	83	2	29337306
Pubmed	Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.	BRINP3 RYR2	3.05e-04	11	83	2	17903301
Pubmed	Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.	LAMA2 LAMA3	3.05e-04	11	83	2	12051813
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP1 LRP1B	3.05e-04	11	83	2	24639464
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMA3	3.05e-04	11	83	2	21524702
Pubmed	Spatial gene expression in the T-stage mouse metanephros.	BMPER SIM1	3.66e-04	12	83	2	16545622
Pubmed	Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.	DYSF RYR2	3.66e-04	12	83	2	23715556
Pubmed	PAF-AH Catalytic Subunits Modulate the Wnt Pathway in Developing GABAergic Neurons.	WNT7B NTN1	3.66e-04	12	83	2	20725507
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA2 LAMA3	3.66e-04	12	83	2	16750824
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMA3	3.66e-04	12	83	2	9396756
Pubmed	Collagen XIV is important for growth and structural integrity of the myocardium.	LAMA2 PLOD2	3.66e-04	12	83	2	22906538
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	LAMA2 LAMA3	4.31e-04	13	83	2	21900571
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	FRAS1 LAMA2 ADAMTS20	4.92e-04	64	83	3	22261194
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	LRP1 LRP1B	5.03e-04	14	83	2	15082773
Pubmed	The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.	LAMA2 LAMA3	5.03e-04	14	83	2	9151674
Pubmed	Transcriptional map of chromosome region 6q16-->q21.	LAMA2 SIM1	5.03e-04	14	83	2	10575223
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB2 BMP1 FRAS1 TENM3 LRP1 LTBP1 BMPER PLOD2 LRP1B NEK9	5.75e-04	1201	83	10	35696571
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA2 LAMA3	5.79e-04	15	83	2	15895400
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	LAMA2 LAMA3	5.79e-04	15	83	2	9264260
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	ADAMTS10 LTBP1	5.79e-04	15	83	2	38871984
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	BMP1 TCF20 ENC1 NTN1 PLOD2	5.96e-04	283	83	5	18854154
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	FRAS1 LRP1 LAMA3 PLOD2	6.56e-04	164	83	4	32409323
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA2 LAMA3	6.61e-04	16	83	2	17601529
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	LAMA3 ADAMTS5	6.61e-04	16	83	2	30579834
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	FRAS1 LAMA3	6.61e-04	16	83	2	16880404
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	LRP1 LAMA2 ARHGAP9	6.66e-04	71	83	3	33541421
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	ADAMTS20 ADAMTS5	7.48e-04	17	83	2	22183742
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	BMP1 LAMA2 LAMA3 LTBP1	8.35e-04	175	83	4	28071719
Pubmed	The role of floor plate contact in the elaboration of contralateral commissural projections within the embryonic mouse spinal cord.	EPHB2 NTN1	8.40e-04	18	83	2	16854408
Pubmed	Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors.	BMP1 BMPER	8.40e-04	18	83	2	19914233
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 ADAMTS19	8.40e-04	18	83	2	35503090
Pubmed	The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance.	NTN1 SIM1	8.40e-04	18	83	2	21068056
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FRAS1 LAMA2	8.40e-04	18	83	2	14730302
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 LAMA3	8.40e-04	18	83	2	11311202
Pubmed	The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.	WNT7B LAMA2	9.37e-04	19	83	2	15817462
Pubmed	A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis.	WNT7B ENC1 LAMA3	1.01e-03	82	83	3	30728831
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA2 LAMA3	1.04e-03	20	83	2	22911573
Pubmed	ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.	ADAMTS20 ADAMTS5	1.04e-03	20	83	2	19922873
Pubmed	A high-resolution anatomical ontology of the developing murine genitourinary tract.	SPINT2 WNT7B	1.15e-03	21	83	2	17452023
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1 LRP1B	1.15e-03	21	83	2	21337463
Pubmed	Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.	WNT7B ASB4	1.15e-03	21	83	2	17158062
Pubmed	Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells.	EPHB2 SIM1	1.26e-03	22	83	2	15162501
Pubmed	Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants.	WNT7B NTN1	1.26e-03	22	83	2	15342729
Pubmed	Modulation of apical constriction by Wnt signaling is required for lung epithelial shape transition.	BMP1 WNT7B	1.26e-03	22	83	2	27913639
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	TENM3 LAMA2	1.26e-03	22	83	2	35245678
Pubmed	Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.	SPINT2 WNT7B LTBP1 ADAMTS5	1.27e-03	196	83	4	19334288
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PHLDB3 ZCCHC14 FRAS1 MARVELD1 FNTB SLC25A39 WNT7B DYSF ADCY7	1.28e-03	1105	83	9	35748872
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	NEXMIF ZC3H13 PLOD2 RYR2	1.29e-03	197	83	4	20811636
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	EPHB2 ADAMTS20	1.38e-03	23	83	2	26027930
Interaction	OS9 interactions	BMP1 FRAS1 IL22RA2 TENM3 LAMA3 NTN1 DYSF PLOD2 LRP1B	2.37e-07	219	81	9	int:OS9
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS19 ADAMTS20 ADAMTS5	4.38e-07	19	61	4	50
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF133 ZNF32 ZNF394 ZNF257 ZNF174 ZNF648 ZNF683 ZNF229 ZNF519	6.37e-04	718	61	9	28
GeneFamily	Laminin subunits	LAMA2 LAMA3	7.23e-04	12	61	2	626
GeneFamily	Low density lipoprotein receptors	LRP1 LRP1B	8.53e-04	13	61	2	634
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	STAB2 CD163	3.72e-03	27	61	2	1253
Coexpression	NABA_MATRISOME	ADAMTS10 ADAMTS19 BMP1 FRAS1 BRINP3 OTOGL WNT7B ISM1 LAMA2 LAMA3 ADAMTS20 NTN1 LTBP1 ADAMTS5 BMPER CCL21 PLOD2 ADAMTSL2	1.35e-09	1008	81	18	MM17056
Coexpression	NABA_MATRISOME	ADAMTS10 ADAMTS19 BMP1 FRAS1 BRINP3 WNT7B ISM1 LAMA2 LAMA3 ADAMTS20 NTN1 LTBP1 ADAMTS5 BMPER CCL21 PLOD2 FBN3 ADAMTSL2	1.78e-09	1026	81	18	M5889
Coexpression	NABA_ECM_GLYCOPROTEINS	FRAS1 OTOGL LAMA2 LAMA3 NTN1 LTBP1 BMPER	2.16e-06	191	81	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	FRAS1 LAMA2 LAMA3 NTN1 LTBP1 BMPER FBN3	2.56e-06	196	81	7	M3008
Coexpression	NABA_ECM_REGULATORS	ADAMTS10 ADAMTS19 BMP1 ADAMTS20 ADAMTS5 PLOD2 ADAMTSL2	9.15e-06	238	81	7	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTS10 ADAMTS19 BMP1 ADAMTS20 ADAMTS5 PLOD2 ADAMTSL2	1.02e-05	242	81	7	MM17062
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS10 ADAMTS19 BMP1 BRINP3 WNT7B ISM1 ADAMTS20 ADAMTS5 CCL21 PLOD2 ADAMTSL2	1.65e-05	738	81	11	MM17058
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_3_CELL	EPHB2 ADAMTS10 SPINT2 TENM3 PRKD1 FBN3	1.69e-05	174	81	6	M45676
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS10 ADAMTS19 BMP1 BRINP3 WNT7B ISM1 ADAMTS20 ADAMTS5 CCL21 PLOD2 ADAMTSL2	1.94e-05	751	81	11	M5885
Coexpression	NABA_CORE_MATRISOME	FRAS1 OTOGL LAMA2 LAMA3 NTN1 LTBP1 BMPER	2.07e-05	270	81	7	MM17057
Coexpression	NABA_CORE_MATRISOME	FRAS1 LAMA2 LAMA3 NTN1 LTBP1 BMPER FBN3	2.32e-05	275	81	7	M5884
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_LATE_AIRWAY_SMC_CELL	BRINP3 NTN1 ADAMTS5 LDLRAD4 ADAMTSL2	2.93e-05	115	81	5	M45671
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MID_AIRWAY_SMC_1_CELL	ENC1 ISM1 LDLRAD4 ADAMTSL2	7.02e-05	71	81	4	M45677
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	BMP1 ITGBL1 TENM3 ISM1 LRP1 LAMA2 NTN1 LTBP1 ADAMTS5 BMPER	3.94e-06	437	77	10	GSM777046_500
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4	ADAMTS10 BMP1 BRINP3 ZNF32 TRMT2A TENM3 ENC1 LAMA2 CFP ASB4 BMPER CCL21 PLOD2 NEK9 LDLRAD4	1.35e-05	1148	77	15	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2	ADAMTS10 BMP1 DUSP28 BRINP3 ZNF32 TENM3 PHF19 FNTB NEXMIF LRP1 LAMA2 NTN1 CFP CCL21 PLOD2	2.45e-05	1208	77	15	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500	ADAMTS19 TENM3 LRP1 ASB4 PRKD1 LTBP1 TOP2A RYR2	8.10e-05	388	77	8	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000	CLIP4 TENM3 PHF19 ENC1 ISM1 LTBP1 BMPER ZNF519	1.02e-04	401	77	8	gudmap_kidney_P1_CapMes_Crym_k1_1000
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 MARVELD1 ENC1 ISM1 NTN1 LTBP1 ADAMTS5 ADAMTSL2	6.45e-11	188	81	9	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CLIP4 BRINP3 ENC1 ISM1 NTN1 LTBP1 ADAMTS5 LDLRAD4 ADAMTSL2	6.76e-11	189	81	9	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 STAB2 ZAN OTOGL ABCA13 ADAMTS20 LRP1B RYR2	1.67e-09	184	81	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 STAB2 ZAN OTOGL ABCA13 ADAMTS20 LRP1B RYR2	1.67e-09	184	81	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 STAB2 ZAN OTOGL ABCA13 ADAMTS20 LRP1B RYR2	1.67e-09	184	81	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CLIP4 BRINP3 ENC1 ISM1 NTN1 LTBP1 LDLRAD4 ADAMTSL2	1.90e-09	187	81	8	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	ITGBL1 FRAS1 TENM3 LAMA2 PRKD1 BMPER RYR2 ADAMTSL2	1.90e-09	187	81	8	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CLIP4 BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 LRP1B ADAMTSL2	2.16e-09	190	81	8	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FRAS1 TENM3 LAMA2 PRKD1 LTBP1 BMPER RYR2	2.34e-09	192	81	8	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	BRINP3 ENC1 ISM1 NTN1 LTBP1 ADAMTS5 LDLRAD4 ADAMTSL2	2.75e-09	196	81	8	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FRAS1 TENM3 LRP1 LAMA2 BMPER RYR2 ADAMTSL2	3.23e-09	200	81	8	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FRAS1 TENM3 LRP1 LAMA2 BMPER RYR2 ADAMTSL2	3.23e-09	200	81	8	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 ENC1 ISM1 LAMA2 LTBP1 BMPER	3.01e-08	173	81	7	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Airway_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	EPHB2 DIPK1C ITGBL1 TENM3 ISM1 LRP1 LTBP1	3.01e-08	173	81	7	b23b408acc29a667cce104429afef1a6cf2720a5
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 ADAMTS5 BMPER	3.52e-08	177	81	7	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 ISM1 LAMA2 NTN1 LTBP1 BMPER	3.95e-08	180	81	7	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ITGBL1 ENC1 ISM1 LAMA2 LTBP1 ZNF519 ADAMTSL2	4.11e-08	181	81	7	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS10 ISM1 LRP1 NTN1 LTBP1 ADAMTS5 RYR2	4.43e-08	183	81	7	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 LDLRAD4 ADAMTSL2	5.13e-08	187	81	7	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 BMPER RYR2	5.13e-08	187	81	7	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CLIP4 BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 ADAMTSL2	5.33e-08	188	81	7	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 ISM1 LAMA2 NTN1 LTBP1 ADAMTS5	5.52e-08	189	81	7	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TENM3 ENC1 LRP1 LAMA2 LTBP1 ADAMTSL2	5.93e-08	191	81	7	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TENM3 ENC1 LRP1 LAMA2 LTBP1 ADAMTSL2	5.93e-08	191	81	7	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 FRAS1 TENM3 LAMA2 PRKD1 BMPER RYR2	5.93e-08	191	81	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 LRP1 LAMA2 ADAMTS5 BMPER ADAMTSL2	6.15e-08	192	81	7	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 LRP1 LAMA2 ADAMTS5 BMPER ADAMTSL2	6.15e-08	192	81	7	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 IL22RA2 LRP1 LAMA2 LTBP1 ADAMTS5 BMPER	6.15e-08	192	81	7	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 LRP1 LAMA2 LTBP1 ADAMTS5 BMPER	6.37e-08	193	81	7	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	ITGBL1 BRINP3 ISM1 LAMA2 PRKD1 LTBP1 RYR2	6.37e-08	193	81	7	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 ENC1 LRP1 LAMA2 ADAMTS5 BMPER	6.60e-08	194	81	7	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 ENC1 LRP1 LAMA2 ADAMTS5 BMPER	6.60e-08	194	81	7	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 ISM1 LRP1 LAMA2 NTN1 LTBP1	6.60e-08	194	81	7	3d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 ENC1 LRP1 LAMA2 ADAMTS5 BMPER	6.60e-08	194	81	7	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BMP1 ITGBL1 ISM1 LRP1 LAMA2 NTN1 LTBP1	6.60e-08	194	81	7	ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TENM3 ISM1 LRP1 LAMA2 LTBP1 ADAMTSL2	6.84e-08	195	81	7	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	CLIP4 ITGBL1 STAB2 TENM3 ISM1 LAMA2 LTBP1	6.84e-08	195	81	7	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TENM3 ISM1 LRP1 LAMA2 LTBP1 ADAMTSL2	6.84e-08	195	81	7	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS10 ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 BMPER	6.84e-08	195	81	7	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	ITGBL1 LAMA2 PRKD1 LTBP1 BMPER RYR2 ADAMTSL2	6.84e-08	195	81	7	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	15-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	BRINP3 ENC1 ISM1 NTN1 LTBP1 ADAMTS5 ADAMTSL2	7.08e-08	196	81	7	0e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 ISM1 LRP1 LAMA2 LTBP1 ADAMTS5	7.08e-08	196	81	7	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ITGBL1 ISM1 LRP1 LAMA2 LTBP1 ADAMTS5	7.08e-08	196	81	7	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	ITGBL1 TENM3 LAMA2 PRKD1 LTBP1 PLOD2 RYR2	7.33e-08	197	81	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	ITGBL1 TENM3 LAMA2 PRKD1 LTBP1 PLOD2 RYR2	7.33e-08	197	81	7	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ITGBL1 TENM3 ENC1 LAMA2 PRKD1 LTBP1 RYR2	7.33e-08	197	81	7	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 ISM1 LRP1 LAMA2 NTN1 LTBP1 ADAMTS5	7.59e-08	198	81	7	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 LRP1B ADAMTSL2	7.85e-08	199	81	7	a207b4891881149d4c50721310690fd794157723
ToppCell	distal-1-mesenchymal-Myofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DIPK1C ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 BMPER	7.85e-08	199	81	7	58c36f5a30c6862b7f5587a0b9bc31da99e43dd5
ToppCell	distal-mesenchymal-Myofibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DIPK1C ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 BMPER	7.85e-08	199	81	7	79917b5225cb45b4a0ea937f79f1752346e4346e
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 TENM3 LRP1 LAMA2 LTBP1 BMPER RYR2	8.13e-08	200	81	7	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	distal-mesenchymal-Myofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS19 ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 BMPER	8.13e-08	200	81	7	61854a459385cd9295be37157a8f81a2c227dff3
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 TENM3 LRP1 LAMA2 LTBP1 BMPER RYR2	8.13e-08	200	81	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 TENM3 LRP1 LAMA2 LTBP1 BMPER RYR2	8.13e-08	200	81	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 ADAMTS5 BMPER	8.13e-08	200	81	7	b441b3771fb7d9ee7b7a104afc35e466aace2da2
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 TENM3 LRP1 LAMA2 LTBP1 BMPER RYR2	8.13e-08	200	81	7	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 ISM1 LRP1 LAMA2 LTBP1 RYR2 ADAMTSL2	8.13e-08	200	81	7	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 ISM1 LAMA2 LTBP1 ADAMTS5	3.98e-07	155	81	6	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D122\|Adult / Lineage, Cell type, age group and donor	ITGBL1 OTOGL LAMA2 LTBP1 BMPER ADAMTSL2	4.45e-07	158	81	6	410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 ZAN OTOGL ABCA13 SIM1 LRP1B	5.16e-07	162	81	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 BRINP3 ISM1 LTBP1 ADAMTS5 BMPER	5.54e-07	164	81	6	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 OTOGL ISM1 LAMA2 LTBP1 BMPER	5.95e-07	166	81	6	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ZAN OTOGL ABCA13 LRP1B RYR2	6.60e-07	169	81	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 ISM1 LRP1 LAMA2 LTBP1 ADAMTS5	7.32e-07	172	81	6	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_T_(gd)\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DIPK1C SPINT2 ZAN NR2E1 ZNF683 DYSF	7.57e-07	173	81	6	62f2f42f54c9c6941bf888956be40230f92c883e
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT2 WTIP SYDE2 LAMA3 ASB4 LRP1B	8.10e-07	175	81	6	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT2 WTIP SYDE2 LAMA3 ASB4 LRP1B	8.10e-07	175	81	6	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 LRP1 LAMA2 LTBP1 LDLRAD4 ADAMTSL2	8.37e-07	176	81	6	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 LRP1 LAMA2 LTBP1 LDLRAD4 ADAMTSL2	8.37e-07	176	81	6	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ITGBL1 TENM3 ISM1 LTBP1 ZNF229 RYR2	8.65e-07	177	81	6	e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ITGBL1 TENM3 ISM1 LTBP1 ZNF229 RYR2	8.65e-07	177	81	6	43ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BMP1 ITGBL1 TENM3 LAMA3 ADAMTS20 ADAMTS5	8.65e-07	177	81	6	6b4fe717928814dafcd13090b1c90ea973938c6d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 BRINP3 LAMA2 LTBP1 ZNF229 RYR2	9.86e-07	181	81	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYDE2 ISM1 LRP1 LTBP1 BMPER ADAMTSL2	1.02e-06	182	81	6	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYDE2 ISM1 LRP1 LTBP1 BMPER ADAMTSL2	1.02e-06	182	81	6	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BRINP3 ENC1 ISM1 LAMA2 LTBP1 ADAMTSL2	1.05e-06	183	81	6	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1C BMP1 IL22RA2 LRP1 LAMA2 ADAMTS5	1.12e-06	185	81	6	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1C BMP1 IL22RA2 LRP1 LAMA2 ADAMTS5	1.12e-06	185	81	6	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	OTOGL LRP1 LAMA3 ADAMTS20 LRP1B RYR2	1.16e-06	186	81	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	EPHB2 ADAMTS10 ENC1 LAMA2 ADAMTS5 ADAMTSL2	1.16e-06	186	81	6	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	ITGBL1 LAMA2 PRKD1 LTBP1 PLOD2 RYR2	1.19e-06	187	81	6	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB2 BMP1 ITGBL1 FRAS1 NTN1 ADAMTS5	1.19e-06	187	81	6	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGBL1 ISM1 NTN1 ADAMTS5 LDLRAD4 RYR2	1.23e-06	188	81	6	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 LDLRAD4	1.23e-06	188	81	6	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRINP3 ENC1 ISM1 LTBP1 LDLRAD4 ADAMTSL2	1.23e-06	188	81	6	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 ADAMTSL2	1.27e-06	189	81	6	da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ISM1 LRP1 NTN1 ADAMTS5 LDLRAD4 RYR2	1.27e-06	189	81	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 DIPK1C SPINT2 ABCA13 SIM1 LRP1B	1.31e-06	190	81	6	68ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP4 SLC6A12 TENM3 LRP1 NTN1 LTBP1	1.31e-06	190	81	6	990ac07f4b0a22041daac7502f74fafd6d258cba
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	BRINP3 ISM1 NTN1 LTBP1 ADAMTS5 LDLRAD4	1.31e-06	190	81	6	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP4 SLC6A12 TENM3 LRP1 NTN1 LTBP1	1.31e-06	190	81	6	fc9bbe5e6e0ec3cfa47bf479d8b09a0fc53169cc
ToppCell	facs-Thymus-Flowthrough-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP4 SLC6A12 TENM3 LRP1 NTN1 LTBP1	1.31e-06	190	81	6	39ecdf8815e235771132684dfc1aff1917e20965
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP4 ADAMTS10 LRP1 LAMA2 RYR2 ADAMTSL2	1.31e-06	190	81	6	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 DIPK1C SPINT2 ABCA13 SIM1 LRP1B	1.31e-06	190	81	6	010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 FRAS1 ISM1 LRP1 NTN1 LTBP1	1.35e-06	191	81	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	E15.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BMP1 ZNF32 SPINT2 NEXMIF WNT7B NDUFS6	1.35e-06	191	81	6	6f5d91a9583bbb30dfaa30dd9c7772995a9196be
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TENM3 ISM1 NTN1 ADAMTS5 LDLRAD4 RYR2	1.35e-06	191	81	6	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ITGBL1 ENC1 ISM1 LTBP1 LDLRAD4 ADAMTSL2	1.39e-06	192	81	6	7ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB2 ITGBL1 TENM3 ISM1 LAMA2 ADAMTS5	1.39e-06	192	81	6	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BMP1 LRP1 LAMA2 NTN1 LTBP1 ADAMTS5	1.39e-06	192	81	6	321850b0f881420c2d57d3e825e365c82fa511ab
Disease	retinal detachment, retinal break	FRAS1 LAMA2 ARHGAP9	1.14e-04	35	79	3	EFO_0005773, EFO_0010698
Disease	Asthma, Occupational	TENM3 PRKD1	3.14e-04	10	79	2	C0264423
Disease	sexual dysfunction	ADAMTS19 PRKD1	3.83e-04	11	79	2	EFO_0004714
Disease	adverse effect, response to xenobiotic stimulus	STAB2 LRP1B LDLRAD4	5.39e-04	59	79	3	EFO_0009658, GO_0009410
Disease	Malignant neoplasm of breast	ZCCHC14 ADAMTS19 BMP1 TRMT2A OTOGL LAMA2 CFP SIM1 DYSF TOP2A	5.79e-04	1074	79	10	C0006142
Disease	muscular dystrophy (is_implicated_in)	LAMA2 DYSF	9.38e-04	17	79	2	DOID:9884 (is_implicated_in)
Disease	juvenile idiopathic arthritis	ABCA13 LAMA2 LTBP1	1.04e-03	74	79	3	EFO_0002609
Disease	Liver Cirrhosis, Experimental	TCF20 ENC1 ARHGAP9 CFP LTBP1 DYSF PLOD2 CD163	1.09e-03	774	79	8	C0023893
Disease	muscular dystrophy (implicated_via_orthology)	LAMA2 DYSF	1.44e-03	21	79	2	DOID:9884 (implicated_via_orthology)
Disease	vital capacity	ADAMTS10 ADAMTS19 TCF20 LAMA2 LTBP1 BMPER CCL21 QTRT1 FBN3 RYR2	1.67e-03	1236	79	10	EFO_0004312
Disease	carpal tunnel syndrome	ADAMTS10 LTBP1 ADAMTSL2	1.78e-03	89	79	3	EFO_0004143
Disease	body weight	ADAMTS10 ZNF133 BRINP3 NEXMIF WNT7B PRKD1 LTBP1 SIM1 LRP1B LDLRAD4	1.94e-03	1261	79	10	EFO_0004338
Disease	Periodontal Pocket	TENM3 ISM1	2.04e-03	25	79	2	EFO_1001393
Disease	peak expiratory flow	ADAMTS10 ZCCHC14 LRP1 ADAMTS5 DYSF FBN3	2.20e-03	498	79	6	EFO_0009718
Disease	Schizophrenia	SLC6A12 TRMT2A ABCA13 NR2E1 LRP1 LAMA2 ADCY7 CD163	2.50e-03	883	79	8	C0036341

Protein segments in the cluster

Peptide	Gene	Start	Entry
CGTYNGTRGLSCKNK	C2orf42	31	Q9NWW7
GTCNTGYMLSQGLCK	BRINP3	461	Q76B58
TQGSDGGAQDCCLKY	CCL21	21	O00585
LCDRGAKLNCYSLSG	ASB4	126	Q9Y574
LQYDKCGVCGGDNSS	ADAMTS5	716	Q9UNA0
GGLQGLLCYCNSSET	ABCA13	526	Q86UQ4
SKCGNFIVVGCYNGL	AASDH	821	Q4L235
LQGLGYSCECRGLIN	ADCY7	1041	P51828
YNLCAGAVKCLLEQG	CLIP4	196	Q8N3C7
RGASCLCQKGYTGTV	FBN3	131	Q75N90
RCVCNLGYEAGASGK	FBN3	706	Q75N90
RNLAGSYTCKCGPGS	FBN3	781	Q75N90
LCRGGTCTNTDGSYK	FBN3	1081	Q75N90
RGGCEQRCLNTLGSY	BMP1	556	P13497
GGACLVYCKNGRSRS	DUSP28	96	Q4G0W2
YRGGGVKACSLTCLA	ADAMTS10	631	Q9H324
IGKSECSSQCGQGYR	ADAMTS20	911	P59510
GITCNRCAKGYQQSR	NTN1	431	O95631
TSCGYQGLDICANGR	ADAMTS19	746	Q8TE59
LYQLLNCGRGNSCGA	PHLDB3	436	Q6NSJ2
VRQGLKCEGCGLNYH	PRKD1	171	Q15139
GGCESSCGKGFYNRQ	FRAS1	541	Q86XX4
SCGKGFYNRQGTCSA	FRAS1	546	Q86XX4
NGGCKQLCLYRGNSR	LRP1B	2151	Q9NZR2
GDVRCSCKAGYTGTQ	LAMA3	1751	Q16787
GRLLTFGCNKCGQLG	NEK9	616	Q8TD19
KNTYGTGCFLLCNTG	GK3P	276	Q14409
VANGGCQQLCLYRGR	LRP1	2161	Q07954
LVYNIICKSCGSGRG	EPHB2	356	P29323
FRCTCGQGYQLSAAK	LTBP1	1101	Q14766
ETKTGTCGYCGLQFR	NDUFS6	106	O75380
GSCGQGRTIRHVYCK	ADAMTSL2	751	Q86TH1
ISCNFPGCRTLAKYG	IL22RA2	86	Q969J5
KYIGGGVCINCTQNT	LAMA2	371	P24043
CKAGTFGLQSARGCV	LAMA2	951	P24043
LLGGKNGVCQYRCRY	PLA2G12B	56	Q9BX93
CCLNTAFAYQKRSGG	CFP	56	P27918
AFAYQKRSGGLCQPC	CFP	61	P27918
QGGGCKFLRYNCSIE	PLOD2	686	O00469
GQVRTFGKKCYNCGQ	ERVK-5	536	Q9HDB9
GGQVRTFGRKCYNCG	ERVK-6	536	Q7LDI9
TFGRKCYNCGQIGHL	ERVK-6	541	Q7LDI9
GKLCGLCGNYNGHKR	BMPER	491	Q8N8U9
KNTYGTGCFLLCNTG	GK2	276	Q14410
LSALYGCGRRCQGKQ	MARVELD1	156	Q9BSK0
GGFQGRCNKLVDGCY	FNTB	286	P49356
GSCGACINGKLYIFG	KLHDC1	71	Q8N7A1
CAIGCKVYITGGRGS	ENC1	336	O14682
CRQLGCGSALKTSYQ	CD163	411	Q86VB7
GCGLQSCQMLVSKGY	RYR2	2271	Q92736
LSKFGARCGLPQTYC	DYSF	1671	O75923
GNQKRTRSCGYACTA	ISM1	236	B1AKI9
RCKCDNSDGSGLVYG	ITGBL1	161	O95965
LCQDYQGGTLAGDLC	DIPK1C	66	Q0P6D2
RNRTYVCKSGNQGGC	NR2E1	46	Q9Y466
GKSCGLCGNYNDIQS	OTOGL	251	Q3ZCN5
GCQVVGLYRLCGSAA	SYDE2	846	Q5VT97
NTVGCRLGKYKGGTC	TRMT2A	256	Q8IZ69
QLDALGCRICLGNTY	QTRT1	61	Q9BXR0
ICLNSGGSNCNKVLY	NEXMIF	936	Q5QGS0
AICQGCLTALGSYNK	SLC6A12	296	P48065
CVLAKRNAGLTCGGY	SIM1	166	P81133
RNAGLTCGGYKVIHC	SIM1	171	P81133
ISGRNRVYKCQGGSC	CLCA4	191	Q14CN2
GNLSNCGCDREKQGY	WNT7B	126	P56706
PYGCSVCGKRFNQSA	ZNF394	496	Q53GI3
ATLGRYGSCGLENIC	ZNF519	66	Q8TB69
PYQCGQCGKSFRQSS	ZNF174	381	Q15697
SSLQSTGKCLLYCNG	SLC25A39	66	Q9BZJ4
NSCNNFIYGGCRGNK	SPINT2	156	O43291
NNGITYLSPCLAGCK	SLCO1B3	476	Q9NPD5
NEILICGKCGLGYHQ	PHF19	111	Q5T6S3
GRFGSLKSGCARYCN	STAB2	706	Q8WWQ8
VLCSGNGQYSKGRCL	TENM3	551	Q9P273
NSGRCFYINSLTGCK	ARHGAP9	226	Q9BRR9
YCSGGGNNKIAQTLR	VN1R4	166	Q7Z5H5
QEAGATLGCYNKGCS	TCF20	1891	Q9UGU0
CDQCGKGFSYGSNLR	ZNF229	686	Q9UJW7
CGECGRGFSQKSNLV	ZNF133	496	P52736
GRNGYGAKLCNIFST	TOP2A	161	P11388
KKSGNLSCYNCGATG	ZCCHC14	901	Q8WYQ9
TRGGAAKRYACELCG	ZNF648	271	Q5T619
IKCGLGIYGAQQACQ	WTIP	226	A6NIX2
LKGLGRRQACGYCVF	PIGM	116	Q9H3S5
LKYQCCVGALGQIFA	WDR87	896	Q6ZQQ6
ARGLTGLKNIGNTCY	USP33	181	Q8TEY7
LYECNICGKSFGQLS	ZNF683	321	Q8IZ20
LKTGNCLYGNTCRFV	ZC3H13	46	Q5T200
LCGQCGKSFTQRGSL	ZNF32	246	P17041
KLCGLCGNYDGNSDN	ZAN	1286	Q9Y493
CKGGYNGLNQCLITT	ZNF257	126	Q9Y2Q1
SGKCLYLGSLVCNQQ	LDLRAD4	21	O15165