Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsterol binding

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11 PTCH1

2.70e-0771756GO:0032934
GeneOntologyMolecularFunctioncholesterol binding

OSBPL2 OSBPL1A OSBPL5 OSBPL6 PTCH1

2.56e-0658755GO:0015485
GeneOntologyMolecularFunctionsteroid binding

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11 PTCH1

1.08e-05133756GO:0005496
GeneOntologyMolecularFunctionalcohol binding

OSBPL2 OSBPL1A OSBPL5 OSBPL6 PTCH1

4.10e-05102755GO:0043178
GeneOntologyMolecularFunctionlipid transfer activity

OSBPL2 APOA5 OSBPL5 APOB

6.24e-0557754GO:0120013
GeneOntologyMolecularFunctioncholesterol transfer activity

OSBPL2 APOA5 APOB

9.73e-0524753GO:0120020
GeneOntologyMolecularFunctionsterol transfer activity

OSBPL2 APOA5 APOB

1.10e-0425753GO:0120015
GeneOntologyMolecularFunctionlipase binding

APOA5 APOB

2.89e-047752GO:0035473
GeneOntologyMolecularFunction3'-5'-RNA exonuclease activity

POLRMT DIS3 TOE1

3.61e-0437753GO:0000175
GeneOntologyMolecularFunctionRNA exonuclease activity, producing 5'-phosphomonoesters

POLRMT DIS3 TOE1

4.55e-0440753GO:0016896
GeneOntologyMolecularFunctionglycosaminoglycan binding

APOA5 LPA NCAN ADGRG1 APOB PTCH1

5.13e-04268756GO:0005539
GeneOntologyMolecularFunctionRNA exonuclease activity

POLRMT DIS3 TOE1

6.45e-0445753GO:0004532
GeneOntologyMolecularFunctionheparin binding

APOA5 LPA ADGRG1 APOB PTCH1

7.81e-04192755GO:0008201
GeneOntologyMolecularFunctionlipid transporter activity

OSBPL2 APOA5 OSBPL5 APOB ABCA7

8.57e-04196755GO:0005319
GeneOntologyMolecularFunction3'-5' exonuclease activity

POLRMT DIS3 TOE1

1.57e-0361753GO:0008408
GeneOntologyMolecularFunctionprotein antigen binding

LPA PLG

1.61e-0316752GO:1990405
GeneOntologyMolecularFunctionexonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

POLRMT DIS3 TOE1

1.64e-0362753GO:0016796
GeneOntologyMolecularFunctionapolipoprotein binding

LPA PLG

2.53e-0320752GO:0034185
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C WDR5

2.53e-0320752GO:0042800
GeneOntologyMolecularFunctionphospholipid transporter activity

OSBPL2 OSBPL5 ABCA7

2.72e-0374753GO:0005548
GeneOntologyMolecularFunctionglutamate receptor binding

SHANK1 GNAS ARPC2

3.52e-0381753GO:0035254
GeneOntologyMolecularFunctionlipid binding

OSBPL2 APOA5 MARK1 OSBPL1A OSBPL5 TMEM175 OSBPL6 OSBPL11 APOB PTCH1

3.75e-039887510GO:0008289
GeneOntologyBiologicalProcesslipid transport

OSBPL2 APOA5 LPA OSBPL1A OSBPL5 OSBPL6 OSBPL11 APOB IRS2 PTCH1 NOS2 ABCA7 WNK4

3.73e-085067613GO:0006869
GeneOntologyBiologicalProcesslipid localization

OSBPL2 APOA5 LPA OSBPL1A OSBPL5 OSBPL6 OSBPL11 APOB IRS2 PTCH1 NOS2 ABCA7 WNK4

1.34e-075657613GO:0010876
GeneOntologyBiologicalProcesscholesterol transport

OSBPL2 APOA5 OSBPL5 OSBPL6 APOB PTCH1 ABCA7

6.28e-07134767GO:0030301
GeneOntologyBiologicalProcesssterol transport

OSBPL2 APOA5 OSBPL5 OSBPL6 APOB PTCH1 ABCA7

8.05e-07139767GO:0015918
GeneOntologyBiologicalProcessorganic hydroxy compound transport

OSBPL2 APOA5 OSBPL5 OSBPL6 APOB PTCH1 ABCA7 WNK4

5.14e-05358768GO:0015850
GeneOntologyBiologicalProcessnegative regulation of cytoskeleton organization

SHANK1 ARHGAP6 SPTB CAMSAP1 SHROOM2 ARPC2

8.11e-05194766GO:0051494
GeneOntologyBiologicalProcessnegative regulation of supramolecular fiber organization

SHANK1 ARHGAP6 SPTB CAMSAP1 SHROOM2 ARPC2

8.82e-05197766GO:1902904
GeneOntologyBiologicalProcesspositive regulation of fibrinolysis

LPA PLG

1.33e-045762GO:0051919
GeneOntologyBiologicalProcessregulation of lipid localization

OSBPL6 OSBPL11 APOB IRS2 PTCH1 ABCA7

1.42e-04215766GO:1905952
GeneOntologyBiologicalProcesscholesterol efflux

APOA5 APOB PTCH1 ABCA7

1.88e-0477764GO:0033344
GeneOntologyBiologicalProcessmuscle cell cellular homeostasis

SGCZ LPA PLG

2.01e-0431763GO:0046716
GeneOntologyBiologicalProcesspharyngeal system development

MEGF8 GATA3 PTCH1

2.65e-0434763GO:0060037
GeneOntologyBiologicalProcesstrans-synaptic signaling by BDNF, modulating synaptic transmission

LPA PLG

2.78e-047762GO:0099183
GeneOntologyBiologicalProcessparathyroid hormone secretion

GATA3 GNAS

2.78e-047762GO:0035898
GeneOntologyBiologicalProcessnegative regulation of protein depolymerization

SPTB CAMSAP1 SHROOM2 ARPC2

3.28e-0489764GO:1901880
GeneOntologyBiologicalProcesscholesterol metabolic process

SCARF1 APOA5 OSBPL1A OSBPL5 APOB

3.41e-04163765GO:0008203
GeneOntologyBiologicalProcesstrans-synaptic signaling by BDNF

LPA PLG

3.70e-048762GO:0099191
GeneOntologyBiologicalProcesspositive regulation of response to wounding

SCARF1 LPA DDR2 PLG

3.88e-0493764GO:1903036
GeneOntologyBiologicalProcessbile acid biosynthetic process

OSBPL2 OSBPL1A OSBPL6

4.31e-0440763GO:0006699
GeneOntologyBiologicalProcessprotein kinase C signaling

ADGRG1 WNK4 ARPC2

4.63e-0441763GO:0070528
GeneOntologyBiologicalProcesssteroid metabolic process

SCARF1 OSBPL2 APOA5 OSBPL1A OSBPL5 OSBPL6 APOB

4.70e-04376767GO:0008202
GeneOntologyBiologicalProcesssecondary alcohol metabolic process

SCARF1 APOA5 OSBPL1A OSBPL5 APOB

4.84e-04176765GO:1902652
GeneOntologyBiologicalProcesssterol metabolic process

SCARF1 APOA5 OSBPL1A OSBPL5 APOB

4.97e-04177765GO:0016125
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

SPTB CAMSAP1 SHROOM2 ARPC2

5.11e-04100764GO:0043242
GeneOntologyCellularComponentperinuclear endoplasmic reticulum

OSBPL2 OSBPL1A OSBPL6

1.52e-0429753GO:0097038
GeneOntologyCellularComponentlipoprotein particle

APOA5 LPA APOB

5.29e-0444753GO:1990777
GeneOntologyCellularComponentplasma lipoprotein particle

APOA5 LPA APOB

5.29e-0444753GO:0034358
GeneOntologyCellularComponentprotein-lipid complex

APOA5 LPA APOB

6.42e-0447753GO:0032994
GeneOntologyCellularComponentMLL3/4 complex

KMT2C WDR5

8.19e-0412752GO:0044666
GeneOntologyCellularComponentchylomicron

APOA5 APOB

9.66e-0413752GO:0042627
MousePhenodecreased susceptibility to induced choroidal neovascularization

LPA PLG NOS2

9.28e-0610613MP:0003434
MousePhenoabnormal mammary gland connective tissue morphology

LPA PLG

1.87e-052612MP:0009507
MousePhenoectropion

LPA PLG

1.87e-052612MP:0006164
MousePhenoesophageal ulcer

LPA PLG

1.87e-052612MP:0004547
MousePhenoduodenal ulcer

LPA PLG

1.87e-052612MP:0003273
MousePhenoperianal ulcer

LPA PLG

1.87e-052612MP:0005035
MousePhenoabsent cornea epithelium

LPA PLG

5.60e-053612MP:0020856
MousePhenochoroidal neovascularization

LPA PLG NOS2

7.29e-0519613MP:0005546
MousePhenoincreased circulating fibrinogen level

LPA PLG

1.12e-044612MP:0012331
MousePhenoproctitis

LPA PLG

1.12e-044612MP:0003305
MousePhenoincreased susceptibility to induced morbidity/mortality

HGFAC MGMT LPA NFKB2 CUZD1 PLG PZP NOS2

1.22e-04346618MP:0009763
MousePhenoabnormal involution of the mammary gland

LPA PLG NOS2

1.50e-0424613MP:0006271
MousePhenoabnormal susceptibility to induced morbidity/mortality

HGFAC MGMT LPA NFKB2 CUZD1 PLG PTCH1 PZP NOS2

1.89e-04471619MP:0020148
MousePhenoabnormal choroid vasculature morphology

LPA PLG NOS2

2.15e-0427613MP:0006237
MousePhenoabnormal mammary gland development

NET1 LPA CUZD1 PLG NOS2

2.18e-04126615MP:0000628
MousePhenoabnormal mammary gland growth during lactation

LPA CUZD1 PLG

2.40e-0428613MP:0006270
MousePhenogastric ulcer

LPA PLG

2.78e-046612MP:0003282
MousePhenoincreased IgG2a level

NFKB2 CD69 NOS2 BANK1

3.01e-0474614MP:0008500
MousePhenohepatic necrosis

LPA SPTB PLG PZP

3.86e-0479614MP:0001654
MousePhenoincreased acute phase protein level

LPA PLG

3.88e-047612MP:0014499
MousePhenovenoocclusion

LPA PLG

3.88e-047612MP:0006137
MousePhenoabnormal conjunctival epithelium morphology

LPA PLG

3.88e-047612MP:0004481
MousePhenopeptic ulcer

LPA PLG

3.88e-047612MP:0003301
MousePhenoabnormal stomach wall morphology

LPA NFKB2 GATA3 PLG

4.05e-0480614MP:0010783
MousePhenoabnormal circulating fibrinogen level

LPA PLG

5.16e-048612MP:0010213
MousePhenodecreased keratinocyte migration

LPA PLG

5.16e-048612MP:0012194
MousePhenoabnormal gland development

NET1 LPA CUZD1 PLG SPEN NOS2

5.19e-04233616MP:0020973
MousePhenodecreased susceptibility to neuronal excitotoxicity

LPA TMEM175 PLG

5.53e-0437613MP:0008236
MousePhenoabnormal mammary gland physiology

LPA CUZD1 PLG NOS2

5.82e-0488614MP:0001881
MousePhenoabnormal apocrine gland physiology

LPA CUZD1 PLG NOS2

5.82e-0488614MP:0013555
DomainOxysterol-bd

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

6.60e-1012745IPR000648
DomainOxysterol-bd_CS

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

6.60e-1012745IPR018494
DomainOxysterol_BP

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

6.60e-1012745PF01237
DomainOSBP

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

6.60e-1012745PS01013
DomainKringle

HGFAC LPA PLG

3.90e-0517743IPR000001
DomainKringle_CS

HGFAC LPA PLG

3.90e-0517743IPR018056
DomainKRINGLE_2

HGFAC LPA PLG

3.90e-0517743PS50070
DomainKringle

HGFAC LPA PLG

3.90e-0517743PF00051
DomainKRINGLE_1

HGFAC LPA PLG

3.90e-0517743PS00021
DomainKR

HGFAC LPA PLG

3.90e-0517743SM00130
DomainPentatricopeptide_repeat

DENND4B POLRMT GNAS

9.99e-0523743IPR002885
DomainKringle-like

HGFAC LPA PLG

2.73e-0432743IPR013806
DomainPH

NET1 OSBPL1A OSBPL5 OSBPL6 OSBPL11 IRS2

8.18e-04278746SM00233
DomainPH_DOMAIN

NET1 OSBPL1A OSBPL5 OSBPL6 OSBPL11 IRS2

8.33e-04279746PS50003
DomainPH_domain

NET1 OSBPL1A OSBPL5 OSBPL6 OSBPL11 IRS2

8.49e-04280746IPR001849
Domain-

MTMR12 NET1 OSBPL1A OSBPL5 OSBPL6 OSBPL11 IRS2

9.01e-043917472.30.29.30
DomainPH_dom-like

MTMR12 NET1 OSBPL1A OSBPL5 OSBPL6 OSBPL11 IRS2

1.48e-03426747IPR011993
DomainPH

NET1 OSBPL5 OSBPL6 OSBPL11 IRS2

2.15e-03229745PF00169
DomainPDZ

SHANK1 MAST4 MAGI3 SHROOM2

2.38e-03141744PF00595
DomainPDZ

SHANK1 MAST4 MAGI3 SHROOM2

2.83e-03148744SM00228
Domain-

SHANK1 MAST4 MAGI3 SHROOM2

2.97e-031507442.30.42.10
DomainPDZ

SHANK1 MAST4 MAGI3 SHROOM2

3.05e-03151744PS50106
DomainPDZ

SHANK1 MAST4 MAGI3 SHROOM2

3.12e-03152744IPR001478
DomainIPT

NFKB2 EBF4

5.10e-0327742SM00429
DomainPSI

SEMA6B MEGF8

7.11e-0332742PF01437
DomainIPT

NFKB2 EBF4

7.11e-0332742IPR002909
DomainPlexin_repeat

SEMA6B MEGF8

7.11e-0332742IPR002165
PathwayREACTOME_LDL_REMODELING

LPA APOB

1.98e-046522M42520
PathwayREACTOME_SCAVENGING_BY_CLASS_F_RECEPTORS

SCARF1 APOB

1.98e-046522M27222
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

OSBPL2 OSBPL1A OSBPL6

2.39e-0433523M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

OSBPL2 OSBPL1A OSBPL6

2.39e-0433523MM14737
PathwayREACTOME_PLASMA_LIPOPROTEIN_REMODELING

APOA5 LPA APOB

2.61e-0434523M27842
Pubmed

The OSBP-related protein family in humans.

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

2.28e-111178511483621
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

3.90e-111278511735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

3.90e-111278512215260
Pubmed

Family of human oxysterol binding protein (OSBP) homologues. A novel member implicated in brain sterol metabolism.

OSBPL2 OSBPL1A OSBPL5 OSBPL6

3.50e-10678410588946
Pubmed

Growth and dissemination of Lewis lung carcinoma in plasminogen-deficient mice.

LPA SPTB PLG

1.09e-0837839373263
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL2 OSBPL1A OSBPL5

6.03e-07878317428193
Pubmed

ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs.

OSBPL2 OSBPL5 OSBPL11

9.03e-07978332734583
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6B KMT2C MEGF8 NFKB2 RRP12 OSBPL5 POLRMT IRS2 PTCH1 CAMSAP1 SPEN ABCA7 BAHCC1

1.02e-061105781335748872
Pubmed

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.

GNAS PTCH1 ZIC1

1.77e-061178325150496
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MTMR12 MAST4 MEGF8 NET1 USO1 OSBPL6 MAGI3 IRS2 GNAS CAMSAP1 WNK4

3.45e-06861781136931259
Pubmed

Significant associations between lipoprotein(a) and corrected apolipoprotein B-100 levels in African-Americans.

LPA APOB

4.97e-06278224859635
Pubmed

OxPL/apoB, lipoprotein(a) and OxLDL biomarkers and cardiovascular disease in chronic hemodialysis patients.

LPA APOB

4.97e-06278221404224
Pubmed

Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.

OSBPL2 OSBPL1A

4.97e-06278211279184
Pubmed

Persistent corneal haze after excimer laser photokeratectomy in plasminogen-deficient mice.

LPA PLG

4.97e-06278210634603
Pubmed

Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis.

LPA PLG

4.97e-06278223943648
Pubmed

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.

LPA PLG

4.97e-0627827705657
Pubmed

Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin.

LPA PLG

4.97e-06278223041318
Pubmed

Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a).

LPA APOB

4.97e-06278226975530
Pubmed

A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis.

LPA PLG

4.97e-06278219752236
Pubmed

Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site.

LPA PLG

4.97e-0627826216475
Pubmed

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus.

LPA PLG

4.97e-06278220440070
Pubmed

A central role for plasminogen in the inflammatory response to biomaterials.

LPA PLG

4.97e-06278215456492
Pubmed

Staphylococcus aureus manganese transport protein C (MntC) is an extracellular matrix- and plasminogen-binding protein.

LPA PLG

4.97e-06278225409527
Pubmed

Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen.

LPA PLG

4.97e-0627828704243
Pubmed

Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.

LPA PLG

4.97e-06278223702659
Pubmed

Lipoprotein (a): impact by ethnicity and environmental and medical conditions.

LPA APOB

4.97e-06278226637279
Pubmed

Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation.

LPA PLG

4.97e-06278222079981
Pubmed

Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice.

LPA PLG

4.97e-0627829490683
Pubmed

Effects of extended-release niacin on the postprandial metabolism of Lp(a) and ApoB-100-containing lipoproteins in statin-treated men with type 2 diabetes mellitus.

LPA APOB

4.97e-06278226515419
Pubmed

Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity.

LPA PLG

4.97e-06278216481742
Pubmed

Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen: a novel mechanism for lipoprotein(a)-mediated inhibition of plasminogen activation.

LPA PLG

4.97e-06278218983515
Pubmed

Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal Progenitors.

LPA PLG

4.97e-06278234378815
Pubmed

Plasmin generation plays different roles in the formation and removal of arterial and venous thrombus in mice.

LPA PLG

4.97e-06278211848464
Pubmed

Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice.

LPA PLG

4.97e-0627827586361
Pubmed

Plasminogen/plasmin modulates bone metabolism by regulating the osteoblast and osteoclast function.

LPA PLG

4.97e-06278221239499
Pubmed

Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice.

LPA PLG

4.97e-06278210642175
Pubmed

Plasminogen mRNA induction in the mouse brain after kainate excitation: codistribution with plasminogen activator inhibitor-2 (PAI-2) mRNA.

LPA PLG

4.97e-06278212225871
Pubmed

Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.

LPA PLG

4.97e-06278237971174
Pubmed

The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis.

LPA PLG

4.97e-0627829884337
Pubmed

Colonic Lesions, Cytokine Profiles, and Gut Microbiota in Plasminogen-Deficient Mice.

LPA PLG

4.97e-06278226473342
Pubmed

Selection of mutant µplasmin for amyloid-β cleavage in vivo.

LPA PLG

4.97e-06278232694536
Pubmed

Intracellular metabolism of human apolipoprotein(a) in stably transfected Hep G2 cells.

LPA APOB

4.97e-0627829548923
Pubmed

Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials.

LPA APOB

4.97e-06278225614280
Pubmed

Role of plasminogen in propagation of scrapie.

LPA PLG

4.97e-06278216103174
Pubmed

Differential expression of oxidized/native lipoprotein(a) and plasminogen in human carotid and cerebral artery plaques.

LPA PLG

4.97e-06278221300353
Pubmed

Selective behaviors altered in plasminogen-deficient mice are reconstituted with intracerebroventricular injection of plasminogen.

LPA PLG

4.97e-06278211306011
Pubmed

Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression.

LPA PLG

4.97e-06278212149246
Pubmed

Protective effects of plasmin(ogen) in a mouse model of Staphylococcus aureus-induced arthritis.

LPA PLG

4.97e-06278218311818
Pubmed

Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus.

LPA PLG

4.97e-06278221190118
Pubmed

A physiological function for apolipoprotein(a): a natural regulator of the inflammatory response.

LPA PLG

4.97e-06278218997104
Pubmed

Growth and behavioral development in plasminogen gene-targeted mice.

LPA PLG

4.97e-06278210885855
Pubmed

Cellular density regulation of plasminogen gene expression in mouse hepatocytes.

LPA PLG

4.97e-06278212559391
Pubmed

Sleep Duration, Lipid Profile and Insulin Resistance: Potential Role of Lipoprotein(a).

LPA APOB

4.97e-06278232630105
Pubmed

Plasminogen is a critical host pathogenicity factor for group A streptococcal infection.

LPA PLG

4.97e-06278215333838
Pubmed

Apo(a) promotes thrombosis in a vascular injury model by a mechanism independent of plasminogen.

LPA PLG

4.97e-06278216150044
Pubmed

Plasminogen has a broad extrahepatic distribution.

LPA PLG

4.97e-06278211916082
Pubmed

Delayed invasion of the kidney and brain by Borrelia crocidurae in plasminogen-deficient mice.

LPA PLG

4.97e-06278211500461
Pubmed

Role of plasminogen activation in neuronal organization and survival.

LPA PLG

4.97e-06278219683575
Pubmed

Plasminogen controls inflammation and pathogenesis of influenza virus infections via fibrinolysis.

LPA PLG

4.97e-06278223555246
Pubmed

Binding of plasminogen to hepatocytes isolated from injured mouse liver and nonparenchymal-cell-dependent proliferation of hepatocytes.

LPA PLG

4.97e-06278218685433
Pubmed

Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide.

LPA PLG

4.97e-06278231462325
Pubmed

Oxidized phospholipids on apolipoprotein B-100 versus plasminogen and risk of coronary heart disease in the PROCARDIS study.

APOB PLG

4.97e-06278235803063
Pubmed

Short-term inhibition of fibrinolytic system restores locomotor function after spinal cord injury in mice.

LPA PLG

4.97e-06278231690812
Pubmed

Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.

LPA PLG

4.97e-06278230254165
Pubmed

Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice.

LPA PLG

4.97e-06278238328826
Pubmed

Reduced transplant arteriosclerosis in plasminogen-deficient mice.

LPA PLG

4.97e-0627829819364
Pubmed

In vivo plasminogen deficiency reduces fat accumulation.

LPA PLG

4.97e-06278212083480
Pubmed

Polymorphonuclear leukocyte phagocytic function increases in plasminogen knockout mice.

LPA PLG

4.97e-06278218420257
Pubmed

Plasminogen alleles influence susceptibility to invasive aspergillosis.

LPA PLG

4.97e-06278218566672
Pubmed

The generation and characterization of mice expressing a plasmin-inactivating active site mutation.

LPA PLG

4.97e-06278220653841
Pubmed

Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis: studies in plasminogen knock-out mice.

LPA PLG

4.97e-06278212428098
Pubmed

Plasminogen deficiency causes reduced corticospinal axonal plasticity and functional recovery after stroke in mice.

LPA PLG

4.97e-06278224732409
Pubmed

Plasminogen promotes macrophage phagocytosis in mice.

LPA PLG

4.97e-06278224876560
Pubmed

Plasminogen is a joint-specific positive or negative determinant of arthritis pathogenesis in mice.

LPA PLG

4.97e-06278224574269
Pubmed

Spontaneous development of otitis media in plasminogen-deficient mice.

LPA PLG

4.97e-06278216956791
Pubmed

Apo(a) and ApoB Interact Noncovalently Within Hepatocytes: Implications for Regulation of Lp(a) Levels by Modulation of ApoB Secretion.

LPA APOB

4.97e-06278235045727
Pubmed

High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins.

LPA APOB

4.97e-06278215654123
Pubmed

The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOrl partial t haplotypes but is not at the tw73 locus.

LPA PLG

4.97e-0627821543918
Pubmed

Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals.

LPA PLG

4.97e-06278217267741
Pubmed

Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells.

LPA PLG

4.97e-06278229990619
Pubmed

Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector.

LPA PLG

4.97e-06278217293777
Pubmed

Metrological traceability in mass spectrometry-based targeted protein quantitation: a proof-of-principle study for serum apolipoproteins A-I and B100.

LPA APOB

4.97e-06278224972322
Pubmed

The Suggestive Effect of Apo A, Apo B, and Apo A/Apo B on Erectile Dysfunction.

LPA APOB

4.97e-06278233423974
Pubmed

Plasminogen plays a crucial role in bone repair.

LPA PLG

4.97e-06278223456978
Pubmed

Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction.

LPA PLG

4.97e-06278210854210
Pubmed

Gender affects skin wound healing in plasminogen deficient mice.

LPA PLG

4.97e-06278223527289
Pubmed

Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice.

LPA PLG

4.97e-0627829770530
Pubmed

Plasminogen activation is required for the development of radiation-induced dermatitis.

LPA PLG

4.97e-06278230323258
Pubmed

Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS.

APOA5 APOB

4.97e-06278224694356
Pubmed

Nonfibrinolytic functions of plasminogen.

LPA PLG

4.97e-06278210816371
Pubmed

Utility of Genetically Predicted Lp(a) (Lipoprotein [a]) and ApoB Levels for Cardiovascular Risk Assessment.

LPA APOB

4.97e-06278234461734
Pubmed

Plasminogen is a critical regulator of cutaneous wound healing.

LPA PLG

4.97e-06278226791370
Pubmed

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma.

LPA PLG

4.97e-0627827525077
Pubmed

Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models.

LPA PLG

4.97e-06278216052596
Pubmed

Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice.

LPA PLG

4.97e-06278217122079
Pubmed

Beta-amyloid (Abeta) causes detachment of N1E-115 neuroblastoma cells by acting as a scaffold for cell-associated plasminogen activation.

LPA PLG

4.97e-06278215737740
Pubmed

Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis.

LPA PLG

4.97e-06278222056679
Pubmed

The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain.

LPA PLG

4.97e-06278218039665
Pubmed

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.

LPA PLG

4.97e-0627829671388
Pubmed

Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis.

LPA PLG

4.97e-06278227319402
InteractionKDM1B interactions

KMT2C USO1 WDR5 ABLIM2 DYNC1I2

2.45e-0658755int:KDM1B
InteractionTOP3B interactions

SEMA6B KMT2C MEGF8 SPTB NFKB2 RRP12 OSBPL5 POLRMT APOB IRS2 GNAS PTCH1 CAMSAP1 SPEN ABCA7 ARPC2 BAHCC1

2.18e-0514707517int:TOP3B
Cytoband10p15

NET1 GATA3

5.95e-05778210p15
CytobandEnsembl 112 genes in cytogenetic band chr6q26

LPA PLG

3.37e-0416782chr6q26
Cytoband6q26

LPA PLG

4.28e-04187826q26
Cytoband19q12

ZNF536 MEGF8

5.31e-042078219q12
Cytoband20q13.3

OSBPL2 GNAS

5.31e-042078220q13.3
CytobandXp22.3

ARHGAP6 SHROOM2

7.04e-0423782Xp22.3
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL2 OSBPL1A OSBPL5 OSBPL6 OSBPL11

9.25e-1112495670
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

NET1 SPTB OSBPL5 OSBPL11 IRS2

2.32e-04206495682
GeneFamilyPDZ domain containing

SHANK1 MAST4 MAGI3 SHROOM2

7.58e-041524941220
GeneFamilyApolipoproteins

APOA5 APOB

1.46e-0321492405
GeneFamilyAnkyrin repeat domain containing

SHANK1 NFKB2 OSBPL1A BANK1

4.14e-03242494403
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

SHANK1 OSBPL2 GSE1 MARK1 DENND4B NCAN PCDH11X ADGRG1 ZIC1

2.75e-05447759Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

SHANK1 KMT2C ZNF536 OSBPL2 GSE1 MARK1 DENND4B PCDH11X IDS EBF4 ZIC1

4.86e-057307511Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

SHANK1 ZNF536 OSBPL2 GSE1 MARK1 DENND4B NCAN ADGRG1 ZDBF2 IDS EBF4 ZIC1

6.46e-058937512Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#5

GSE1 DENND4B NCAN PCDH11X ADGRG1 ZIC1

1.05e-04212756Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K5
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC ARHGAP6 OSBPL5 CD69 ADGRG1 PLG

6.40e-07177776c1f838e425ebb04482829b1957e3c1347127e6de
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 NFKB2 CD69 IRS2 BANK1 DMXL1

1.03e-061927762de242d81dc085ae734eb7d1f091af9a542e0866
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 NFKB2 CD69 IRS2 BANK1 DMXL1

1.03e-06192776ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCellfacs-Liver-Non-hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 SPTB APOB PLG PZP

5.88e-061487755c853637f6058f78608ba0e76cda72a548d40710
ToppCellfacs-Liver-Non-hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 SPTB APOB PLG PZP

5.88e-06148775763c598826445bf627989220cd7acd71c4f1ea36
ToppCellfacs-Liver-Non-hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 SPTB APOB PLG PZP

5.88e-06148775d3f224128593251b72429a1cd52e82f77df8e386
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

8.85e-06161775274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCelldroplet-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

9.39e-06163775a794540f2d8984f963c08f05175e4bc916fcc224
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

9.39e-0616377503d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

9.39e-061637751c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCelldroplet-Liver-Hepatocytes-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

9.39e-061637757e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

SPTB OSBPL5 PTCH1 ABLIM2 BAHCC1

1.09e-05168775c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

1.09e-05168775b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG PZP

1.09e-05168775073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

RP1L1 ADGRG1 CLSTN1 SPEN DIS3

1.18e-05171775adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellImmune_cells-B_cell|Immune_cells / Lineage and Cell class

SHANK1 HGFAC CD69 BANK1 DMXL1

1.22e-05172775b646894b691a99bf2742bd9da8e578dff0e87f1f
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP6 ZNF536 DDR2 PCDH11X PTCH1

1.29e-05174775f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

HGFAC LPA APOB PLG PZP

1.29e-051747755aa2fb631505600f37d2b87b02def7be139dc262
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

HGFAC APOA5 LPA LINC01554 PLG

1.32e-051757757f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

HGFAC APOA5 LPA LINC01554 PLG

1.32e-05175775bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGFAC LPA APOB PLG PZP

1.36e-05176775b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCARF1 SEMA6B ZNF469 ABLIM2 NOS2

1.64e-05183775dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 SGCZ ZNF536 DDR2 PTCH1

1.64e-051837757eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC IRS2 PLG PZP OPLAH

1.64e-05183775d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCARF1 SEMA6B ZNF469 ABLIM2 NOS2

1.64e-051837754759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellIPF-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

MAST4 GSE1 OSBPL6 CD69 PZP

1.69e-051847757326a16d7d3ae41b8c9d2beaec7f977b374f3469
ToppCellIPF-Myeloid-Mast|World / Disease state, Lineage and Cell class

MAST4 GSE1 OSBPL6 CD69 PZP

1.69e-051847757aefa182acad5a53c730945fec85329d7168606a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFKB2 CD69 ZDBF2 IDS BANK1

1.73e-05185775e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

MAST4 GSE1 OSBPL6 CD69 PZP

1.78e-05186775def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellCOPD-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

MAST4 GSE1 OSBPL6 CD69 PZP

1.97e-05190775379dbac19110b76079a7a53209569e060a852acb
ToppCellnormal_Lymph_Node-T/NK_cells-CD4+_Th|T/NK_cells / Location, Cell class and cell subclass

NFKB2 GATA3 CD69 IRS2 IDS

2.23e-051957755de6841fa04f6fe6f0c2aa6c300667a25ae6d52e
ToppCellHealthy/Control-gd_T|Healthy/Control / Disease group and Cell class

GATA3 CD69 ADGRG1 IDS PZP

2.28e-05196775a6f9e55cd1cd7facadb3f508bded68023c997f3f
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

BPTF KMT2C NFKB2 ADGRG1 GNAS

2.28e-051967757bced0cc2112697593c478fa291b8ed3941fb811
ToppCellHealthy/Control-gd_T|World / Disease group and Cell class

GATA3 CD69 ADGRG1 IDS PZP

2.28e-05196775b982c84552e7efbff2be861f0f569f40804f5d88
ToppCellHealthy_donor-gd_T|Healthy_donor / disease group, cell group and cell class (v2)

GATA3 CD69 ADGRG1 IDS PZP

2.40e-0519877525158815287efbdd8f463baa755cbb874f3905f3
ToppCellHealthy_donor-gd_T|World / disease group, cell group and cell class (v2)

GATA3 CD69 ADGRG1 IDS PZP

2.40e-051987750c3475936f148f2c026501c61b43bcb94d320c48
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-Treg|Bac-SEP / Disease, condition lineage and cell class

OSBPL2 PCDH11X GATA3 ZDBF2 ACTL10

2.46e-05199775e0b6136e28b813299b7ffbe37f1cf830e60cd7d8
ToppCelldroplet-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.17e-04145774f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.23e-0414777400619115b9a1ec2b967c2992043b41974ece63c4
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ZNF536 OSBPL6 PLG C7orf57

1.30e-041497746399c5a2f06d79f020dece252526f1c0c110d569
ToppCellCOVID-19_Severe-B_cell|World / disease group, cell group and cell class

CD69 PLG BANK1 EBF4

1.30e-041497749a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.33e-04150774ee2da4f684add821f2653d5db8eef46cd95c0fda
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.36e-04151774cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.36e-04151774e243b6c76e59035f10519a86399b598dd2123f87
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.36e-041517747758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.36e-04151774cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.36e-04151774b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.40e-041527741febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.40e-04152774faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.40e-04152774c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGAP6 ZNF536 MARK1 WNK4

1.43e-041537741524557514668f515ac1bbe847611f564b265b42
ToppCellCOVID-19_Severe-B_cell|COVID-19_Severe / disease group, cell group and cell class

CD69 PLG BANK1 EBF4

1.43e-04153774701a7d92ee7b22277c8462742a530347cc6f061a
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.47e-04154774a5289000597068ee8d559f89bce7bce31f35dd57
ToppCelldroplet-Liver-nan-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.58e-04157774b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Vcan_(SNc)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CUZD1 CCDC168 PZP

1.61e-046177312de8c495c7f47ecd720f29a573471705603732a
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Vcan_(SNc)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CUZD1 CCDC168 PZP

1.61e-0461773a655232c6d92335eb086723ab9b05eb3a5479b68
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.62e-041587749f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD69 ZDBF2 BANK1 WNK4

1.66e-041597741dde4d19cc0fde7ebbccb4c31bb845a92206021b
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOA5 APOB PLG PZP

1.70e-041607748de1fc75241d9bf2b355afa0e9ef39fea1977177
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

WDR5 CCDC168 CAMSAP1 C7orf57

1.70e-0416077419105debef96ea0c267d6a1d332303ec668ae47e
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ USO1 MARK1 RRP12

1.83e-04163774132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_large-bowel / Manually curated celltypes from each tissue

OSBPL5 ADGRG1 NOS2 BAHCC1

1.96e-0416677413bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTCH1 NOS2 ABCA7 DIS3

2.01e-04167774a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG

2.10e-04169774f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG

2.10e-041697747785cab967a33560830c394c918d6ce625103858
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

GSE1 SPTB CD69 PZP

2.10e-04169774fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellControl-Myeloid-Mast|Control / Disease state, Lineage and Cell class

MAST4 GSE1 CD69 PZP

2.15e-041707749a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GATA3 PTCH1 ABLIM2 WNK4

2.15e-0417077455fe16d98ea284d05fb899888e4569c685644c7b
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

GSE1 SPTB CD69 PZP

2.15e-04170774c80f6d29096c372da95a8407f402349ff1bb7018
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

ARHGAP6 MARK1 DDR2 ABLIM2

2.20e-04171774080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

MAST4 GSE1 CD69 PZP

2.20e-04171774ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e-Excitatory_Neuron.Sc17a7.Sema3e-Onecut2_(Layer_6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RP1L1 APOB PLG

2.23e-04687735af7170acc5e4503375d84472d538e7f5dc92e1d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

OSBPL6 CD69 IRS2 PZP

2.25e-041727743a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGFAC SGCZ OSBPL1A CD69

2.25e-04172774a03f30a996a9474ad4cccd209476423a042df002
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGFAC SGCZ OSBPL1A CD69

2.25e-04172774f92a53ad2e464cd68ba1714bcc1d5911479cdf1c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

OSBPL6 CD69 IRS2 PZP

2.25e-04172774cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MTMR12 OSBPL5 CD69 ADGRG1

2.35e-04174774009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

APOA5 LPA APOB PLG

2.35e-04174774452932f08cf53e5949672a025d78cecb874aa4b0
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC APOA5 APOB PLG

2.40e-041757745c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellControl-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

MAST4 GSE1 CD69 PZP

2.45e-041767740c5916d63e1ada09105e46d2429b75129b7329ec
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 DDR2 PTCH1 DIS3

2.56e-0417877427497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC OSBPL5 ADGRG1 PLG

2.56e-04178774cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 DDR2 PTCH1 DIS3

2.56e-04178774d348a9550db940d204706529759dc51e30506b5f
ToppCelldroplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP6 GATA3 CD69 ADGRG1

2.56e-041787748aef208b6351143562c87715bb11628880abce94
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC ARHGAP6 ZNF536 DDR2

2.61e-041797740b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGAP6 ZNF536 MARK1 PTCH1

2.67e-0418077401f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGFAC ARHGAP6 ZNF536 PTCH1

2.73e-04181774fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFKB2 CD69 ZDBF2 BANK1

2.73e-04181774d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA6B MAST4 ADGRG1

2.78e-04182774840427d1c23d60482c943ff006b14007ed44d247
ToppCellHSPCs-Ery/Mk_prog.|HSPCs / Lineage and Cell class

NFKB2 CD69 ADGRG1 ARPC2

2.84e-0418377459cfb02143b6b54dfca7560562e064948f0340ca
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGCZ ZNF536 DDR2 PTCH1

2.84e-0418377412daaea821e49bc94a01e2496331e92a80d27339
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP6 ZNF536 OSBPL6 PTCH1

2.84e-04183774af8d86f15a549064530d94bd47081daf59d58ecd
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OTUB2 MTMR12 ACTL10 EBF4

2.90e-04184774b8ecf58b3bdb25bcba5efc2d764930bb84ab95c8
ToppCellSerous|World / shred by cell class for bronchial biopsy

LINC01554 IRS2 GNAS WNK4

2.90e-0418477409d0d1525c11dd326efd942684c03f79d992cf3b
ToppCellIPF-Myeloid-Mast|IPF / Disease state, Lineage and Cell class

MAST4 GSE1 CD69 PZP

2.90e-04184774c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OTUB2 MTMR12 ACTL10 EBF4

2.90e-04184774b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGCZ ZNF536 DDR2 PTCH1

2.96e-041857746712512100ccef456d2e2bd201d0987986c92ac9
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ZNF536 NET1 MARK1 DDR2

2.96e-04185774427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC OSBPL5 ADGRG1 PLG

2.96e-041857745527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGCZ ZNF536 DDR2 PTCH1

2.96e-041857743b2dfc8f4c87be516265dbecfc251276034d0efd
ComputationalNeighborhood of IGFBP1

HGFAC LPA APOB PLG

1.26e-0457494CAR_IGFBP1
ComputationalNeighborhood of HPX

HGFAC LPA APOB PLG

3.29e-0473494CAR_HPX
Drugsterol

SCARF1 OSBPL2 OSBPL1A OSBPL6 OSBPL11 APOB IRS2 PTCH1 ABCA7

2.77e-07265779CID000001107
Drugvirus Tat

APOA5 LPA APOB PLG

2.78e-0717774CID000071655
DrugImplanon

OSBPL2 OSBPL5 OSBPL6 OSBPL11 APOB

5.32e-0747775CID000040976
DrugAC1Q6PCP

OSBPL2 NFKB2 OSBPL5 OSBPL6 OSBPL11 GNAS NOS2 WNK4

1.11e-06230778CID000005267
Drugcortisone

APOA5 LPA NFKB2 CD69 APOB NOS2

1.35e-06103776CID000222786
Drug17-isoprogesterone

OSBPL2 APOA5 USO1 LPA NFKB2 OSBPL5 OSBPL6 OSBPL11 APOB IRS2 GNAS PLG PTCH1 PZP NOS2 DIS3

1.50e-0611707716CID000004920
DrugE-guggulsterone

OSBPL2 NFKB2 OSBPL5 OSBPL6 OSBPL11 NOS2

1.79e-06108776CID006439929
DrugCDRI-85/287

OSBPL2 OSBPL5 OSBPL6 OSBPL11

2.69e-0629774CID000159508
Drugethylnylestradiol

SCARF1 OSBPL2 APOA5 LPA NFKB2 OSBPL5 OSBPL6 OSBPL11 APOB WDR5 GNAS PLG IDS PTCH1 PZP NOS2

3.57e-0612517716CID000003285
Druglynestrenol

APOA5 LPA APOB PZP

8.18e-0638774CID000005857
Drug2bqv

LPA APOB

1.13e-052772CID005327090
Drug25-hydroxycholesterol

OSBPL2 OSBPL5 OSBPL6 OSBPL11 APOB NOS2

1.72e-05160776CID000065094
DrugRo 16-6532

APOA5 LPA NFKB2 APOB

2.47e-0550774CID000122787
Drug4-hydroxy-3-nitrophenylacetyl (NP) caproic

LPA PTCH1 NOS2

2.93e-0518773CID000444167
Drugdesogestrel

APOA5 LPA APOB PLG PZP

3.01e-05106775CID000040973
Drugmagnesium fluoride

WDR5 GNAS SPEN ATF6B

3.12e-0553774CID000024546
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

BPTF DENND4B GATA3 SPEN TOE1 ZIC1

3.14e-051787761112_DN
Drughomocysteine

APOA5 LPA NFKB2 APOB PLG NOS2 OPLAH

3.29e-05266777CID000000778
DrugAminocaproic Acid

LPA PLG

3.38e-053772DB00513
Drugmenthol glucuronide

APOB SPEN

3.38e-053772CID000133208
DrugCAS 93957-55-2

APOA5 LPA NFKB2 CD69 APOB NOS2

4.14e-05187776CID000003403
Drugsodium molybdate

OSBPL2 OSBPL5 OSBPL6 OSBPL11

4.17e-0557774CID000061424
Drugpitavastatin

APOA5 LPA NFKB2 APOB NOS2

4.27e-05114775CID005282451
Drugepicholesterol

SCARF1 OSBPL2 APOA5 LPA NFKB2 OSBPL6 APOB PLG PTCH1 ABCA7

5.49e-056367710CID000000304
DrugNSC9564

LPA APOB PLG PZP

7.00e-0565774CID000004536
DrugExosurf

APOA5 LPA NFKB2 APOB

7.88e-0567774CID000071388
DrugN-acetylcysteine

PITHD1 MGMT LPA NFKB2 APOB GNAS PLG NOS2 OPLAH

9.31e-05546779CID000000581
Drugsulfate

SCARF1 HGFAC MGMT LPA SPTB NCAN NFKB2 CD69 APOB WDR5 PLG IDS NOS2 DYNC1I2

9.74e-0512927714CID000001117
DrugAC1L1E7N

APOA5 LPA NFKB2 APOB NOS2

1.02e-04137775CID000002676
Drug17alpha-estradiol

SCARF1 OSBPL2 APOA5 USO1 LPA NFKB2 OSBPL5 OSBPL6 OSBPL11 CD69 APOB IRS2 PZP NOS2

1.07e-0413037714CID000000450
DrugSedalipid

LPA APOB

1.12e-045772CID000173846
Drugpipecolamide

PLG PTCH1

1.12e-045772CID000140623
DrugAdvicor

LPA APOB

1.12e-045772CID000151176
Drugsulfite

HGFAC MGMT SPTB PCDH11X GNAS IDS SPEN NOS2

1.16e-04438778CID000001099
Drugvitamin E

SCARF1 APOA5 LPA NFKB2 POLRMT APOB NOS2 OPLAH

1.22e-04441778CID000002116
DrugH088

APOA5 APOB PLG PZP

1.23e-0475774CID000004542
Diseasecholesteryl esters to total lipids in small LDL percentage

HGFAC APOA5 LPA NCAN APOB PLG

1.16e-0942766EFO_0022255
Diseasetriglycerides in LDL measurement

BPTF HGFAC LPA APOB PLG

3.42e-0756765EFO_0022320
Diseasecholesteryl ester measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB PLG

4.14e-07110766EFO_0008317, EFO_0008596, EFO_0010351
Diseasechylomicron measurement, total cholesterol measurement, very low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB PLG

4.14e-07110766EFO_0004574, EFO_0008317, EFO_0008596
Diseasetriglycerides in small VLDL measurement

BPTF HGFAC LPA APOB PLG

5.27e-0761765EFO_0022145
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA RP1L1 APOB WDR5 PLG

5.45e-07274768EFO_0004530, EFO_0004612
Diseasetriglycerides in small HDL measurement

BPTF HGFAC LPA APOB PLG

5.72e-0762765EFO_0022158
Diseasephospholipids in large VLDL measurement

BPTF HGFAC LPA APOB PLG

5.72e-0762765EFO_0022169
Diseasetriglycerides in medium LDL measurement

BPTF HGFAC LPA APOB PLG

5.72e-0762765EFO_0022322
Diseasetriglycerides to total lipids in very large HDL percentage

BPTF HGFAC LPA APOB PLG

5.72e-0762765EFO_0022339
Diseasetriglycerides in small LDL measurement

BPTF HGFAC LPA APOB PLG

7.26e-0765765EFO_0022323
Diseasetotal lipids in very large HDL measurement

HGFAC LPA APOB PLG BANK1

7.84e-0766765EFO_0022312
Diseasephospholipids in very large HDL measurement

HGFAC LPA APOB PLG BANK1

7.84e-0766765EFO_0022298
Diseasetriglycerides to phosphoglycerides ratio

HGFAC LPA APOB PLG BANK1

9.11e-0768765EFO_0022327
Diseasecholesterol in very large HDL measurement

HGFAC LPA APOB PLG BANK1

9.80e-0769765EFO_0022229
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA APOB PLG BANK1

1.06e-06206767EFO_0004612, EFO_0020947
Diseasepolyunsaturated fatty acid measurement

HGFAC APOA5 LPA NCAN APOB PLG

1.16e-06131766EFO_0010733
Diseasevery low density lipoprotein particle size measurement

HGFAC APOA5 LPA NCAN APOB PLG

1.26e-06133766EFO_0008594
Diseasefree cholesterol to total lipids in large LDL percentage

HGFAC LPA APOB PLG BANK1

1.39e-0674765EFO_0022280
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

1.41e-06215767EFO_0008317, EFO_0008591
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

1.65e-06220767EFO_0004529, EFO_0008317
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

1.85e-06224767EFO_0004530, EFO_0008317
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

1.85e-06224767EFO_0004574, EFO_0008317
Diseasephospholipids:total lipids ratio

BPTF HGFAC LPA NCAN APOB PLG BANK1

2.03e-06227767EFO_0020946
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

2.15e-06229767EFO_0004639, EFO_0008317
Diseasetriglyceride measurement, phospholipid measurement

BPTF HGFAC APOA5 LPA APOB PLG

2.18e-06146766EFO_0004530, EFO_0004639
Diseasecholesteryl esters to total lipids in medium LDL percentage

HGFAC LPA APOB PLG

2.52e-0637764EFO_0022252
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

HGFAC APOA5 LPA NCAN APOB PLG

2.85e-06153766EFO_0004611, EFO_0020946
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

HGFAC APOA5 LPA NCAN APOB PLG

2.85e-06153766EFO_0004611, EFO_0020944
Diseaselipid measurement, lipoprotein measurement

HGFAC APOA5 LPA NCAN APOB

3.67e-0690765EFO_0004529, EFO_0004732
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA APOB PLG

4.57e-06166766EFO_0004530, EFO_0004611
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

HGFAC APOA5 LPA APOB PLG

4.80e-0695765EFO_0004529, EFO_0008317, EFO_0008596
Diseasevery low density lipoprotein cholesterol measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

4.95e-06260767EFO_0008317
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA APOB PLG

5.05e-0696765EFO_0004530, EFO_0008317, EFO_0008596
Diseasehigh density lipoprotein particle size measurement

HGFAC APOA5 LPA APOB PLG BANK1

5.24e-06170766EFO_0008592
Diseasetriglyceride measurement, alcohol consumption measurement

HGFAC LPA TMEM175 APOB PLG

6.48e-06101765EFO_0004530, EFO_0007878
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA APOB PLG

8.21e-06106765EFO_0008317, EFO_0008596
Diseaselinoleic acid measurement

HGFAC MAST4 APOA5 LPA APOB PLG

8.77e-06186766EFO_0006807
Diseasecholesterol to total lipids in small HDL percentage

APOA5 LPA APOB PLG

9.26e-0651764EFO_0022240
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement

HGFAC APOA5 LPA APOB PLG

9.40e-06109765EFO_0004639, EFO_0008317, EFO_0008596
Diseasefree cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA APOB PLG

9.83e-06110765EFO_0008317, EFO_0008591, EFO_0008596
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

BPTF HGFAC APOA5 LPA APOB PLG BANK1

1.03e-05291767EFO_0008317, EFO_0020946
Diseasetriglycerides in HDL measurement

APOA5 LPA APOB PLG

1.08e-0553764EFO_0022317
Diseasetriglycerides in medium HDL measurement

APOA5 LPA APOB PLG

1.17e-0554764EFO_0022321
Diseaseomega-6 polyunsaturated fatty acid measurement

HGFAC APOA5 LPA NCAN APOB PLG

1.22e-05197766EFO_0005680
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

HGFAC APOA5 LPA APOB PLG BANK1

1.33e-05200766EFO_0004611, EFO_0020945
Diseasefree cholesterol to total lipids in large HDL percentage

HGFAC LPA APOB PLG

1.35e-0556764EFO_0022279
Diseaseglycoprotein measurement

HGFAC APOA5 LPA APOB PLG

1.44e-05119765EFO_0004555
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

HGFAC LPA APOB PLG

1.90e-0561764EFO_0008317, EFO_0008596, EFO_0020946
Diseasecholesteryl ester measurement, low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB

1.90e-05126765EFO_0004611, EFO_0010351
Diseasefree cholesterol in very large HDL measurement

HGFAC LPA APOB PLG

2.02e-0562764EFO_0022273
DiseaseHETE measurement

SGCZ GSE1 APOA5 PCDH11X

2.02e-0562764EFO_0801166
Diseasefree cholesterol to total lipids in medium LDL percentage

HGFAC LPA APOB PLG

2.16e-0563764EFO_0022283
Diseaselipid measurement, high density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN RP1L1 APOB PLG

2.32e-05330767EFO_0004529, EFO_0004612
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB PLG

2.58e-05225766EFO_0008317, EFO_0010351
Diseasefree cholesterol in large VLDL measurement

HGFAC LPA APOB PLG

2.92e-0568764EFO_0022265
Diseasetriglycerides to total lipids in very small VLDL percentage

HGFAC LPA APOB PLG

3.09e-0569764EFO_0022341
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C GNAS NOS2

3.20e-0524763C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C GNAS NOS2

3.20e-0524763C3805278
Diseasecholesteryl esters to total lipids in very small VLDL percentage

HGFAC LPA APOB BANK1

3.46e-0571764EFO_0022259
Diseasestomach cancer (is_implicated_in)

KMT2C GSE1 DDR2 PTCH1

3.66e-0572764DOID:10534 (is_implicated_in)
Diseasetriglycerides to total lipids in small HDL percentage

LPA APOB PLG BANK1

3.66e-0572764EFO_0022336
Diseasephospholipids in large HDL measurement

LPA APOB PLG BANK1

3.87e-0573764EFO_0022190
Diseasetotal lipids in large HDL

LPA APOB PLG BANK1

4.08e-0574764EFO_0022189
DiseaseCholangiocarcinoma

KMT2C GNAS NOS2

4.09e-0526763C0206698
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

HGFAC LPA APOB PLG

5.02e-0578764EFO_0022187
Diseasefree cholesterol in large HDL measurement

LPA APOB PLG BANK1

5.27e-0579764EFO_0022157
Diseasecholesteryl ester measurement

HGFAC APOA5 LPA APOB PLG BANK1

5.41e-05257766EFO_0010351
Diseasecholesterol in large HDL measurement

LPA APOB PLG BANK1

5.54e-0580764EFO_0021900
Diseaseplasma plasminogen measurement

LPA PLG

6.51e-055762EFO_0006309
Diseasechronic kidney disease, APOL1 risk genotype carrier status

LPA PLG

6.51e-055762EFO_0003884, EFO_0009324
Diseasecholesteryl esters to total lipids in large LDL percentage

HGFAC LPA APOB

7.01e-0531763EFO_0022249
Diseasechylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

LPA APOB PLG

9.28e-0534763EFO_0008317, EFO_0008596, EFO_0020947
Diseaseangiostatin measurement

LPA PLG

9.75e-056762EFO_0008024
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

HGFAC LPA APOB PLG

1.27e-0499764EFO_0004611, EFO_0007878
Diseasetriglyceride measurement, alcohol drinking

HGFAC LPA TMEM175 PLG

1.27e-0499764EFO_0004329, EFO_0004530
Diseasefatty acid measurement

BPTF HGFAC APOA5 LPA NCAN APOB PLG

1.33e-04436767EFO_0005110
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

HGFAC APOA5 LPA APOB PLG BANK1

1.33e-04303766EFO_0004612, EFO_0020945
Diseaselipoprotein A measurement, apolipoprotein A 1 measurement

LPA PLG

1.36e-047762EFO_0004614, EFO_0006925
Diseasepancreatic cancer (is_marker_for)

MGMT GNAS PTCH1 NOS2

1.37e-04101764DOID:1793 (is_marker_for)
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

HGFAC LPA APOB PLG

1.43e-04102764EFO_0004329, EFO_0004611
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

APOA5 LPA APOB BANK1

1.48e-04103764EFO_0008595, EFO_0020944
Diseaselipoprotein-associated phospholipase A(2) measurement

LPA APOB PLG

1.51e-0440763EFO_0004746
Diseasedocosahexaenoic acid measurement, fatty acid measurement

APOA5 LPA APOB

1.51e-0440763EFO_0005110, EFO_0007761
Diseasecholesteryl ester measurement, high density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB PLG

1.56e-04312766EFO_0004612, EFO_0010351
Diseaseclinical treatment

APOA5 APOB PLG

1.63e-0441763EFO_0007056
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB PLG

1.65e-04315766EFO_0004574, EFO_0004612
Diseasemetabolic syndrome

BPTF APOA5 LPA APOB PLG

1.70e-04200765EFO_0000195
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

APOA5 LPA PLG

1.75e-0442763EFO_0008317, EFO_0008596, EFO_0020945
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

HGFAC APOA5 LPA NCAN APOB PLG

1.82e-04321766EFO_0004612, EFO_0004639
Diseasenasopharynx carcinoma (is_marker_for)

KMT2C DDR2 SPEN

1.88e-0443763DOID:9261 (is_marker_for)
Diseasecholesteryl esters to total lipids in small HDL percentage

APOA5 LPA APOB

1.88e-0443763EFO_0022254
Diseasefree cholesterol to total lipids in very small VLDL percentage

LPA APOB PLG

1.88e-0443763EFO_0022290
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

BPTF APOA5 LPA APOB

1.98e-04111764EFO_0004530, EFO_0008595
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KMT2C MGMT SPEN

2.16e-0445763DOID:3748 (is_implicated_in)
DiseaseLiver Diseases, Parasitic

KMT2C GNAS

2.33e-049762C0023897
Diseaseomega-3 polyunsaturated fatty acid measurement

APOA5 LPA NCAN APOB

2.50e-04118764EFO_0010119
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

APOA5 LPA APOB BANK1

2.75e-04121764EFO_0008595, EFO_0020943
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

HGFAC APOA5 LPA APOB PLG

2.76e-04222765EFO_0008317, EFO_0020943
DiseasePseudohypoaldosteronism, Type I

GNAS WNK4

2.91e-0410762C0268436

Protein segments in the cluster

PeptideGeneStartEntry
SHAPSRDPRDHQGSV

nan

41

Q6ZR03
YIPSTQNPAFHHESR

BANK1

426

Q8NDB2
RDPARHHPASFSVGN

ACTL10

96

Q5JWF8
TSEPVARAHSVAHAG

BAHCC1

1051

Q9P281
ASHTAPQVLFSHREP

ARPC2

191

O15144
HSHPAAFEPSRQAAV

GSE1

606

Q14687
VQELHRSVAPHAPAS

APOA5

206

Q6Q788
STYQQAPRHFHVPDT

ABLIM2

411

Q6H8Q1
AAQPQFVHPEHRSFV

CLSTN1

826

O94985
VSSHVPSEAQPTHAQ

BPTF

2431

Q12830
QPTPFALHHAASCEV

CAMSAP1

471

Q5T5Y3
HFHIAASINPATDIP

DMXL1

356

Q9Y485
VQHSSHRFSAPEVPA

ABCA7

1311

Q8IZY2
AQSPPASHAHLQVAA

PZP

571

P20742
FRIRFHDPSPAQSHT

NET1

466

Q7Z628
SPHFSTRHEGSFQVP

CD69

26

Q07108
VRNASGFHLPEDPSH

NOS2

961

P35228
TALNHHVFPEAATPS

OTUB2

201

Q96DC9
VTPVTNQRHSDPYAH

KMT2C

2191

Q8NEZ4
PPSSHFASIFEESHV

MAGI3

1131

Q5TCQ9
QLVHQHPPAFEFTET

MTMR12

461

Q9C0I1
DVNPSARFVTVPLHH

DDR2

326

Q16832
VPALHHPVFQQESFT

MGMT

81

P16455
QRTPLSAAAHTHPVY

DYNC1I2

371

Q13409
DLSPAPAARHSHVAV

MEGF8

271

Q7Z7M0
VQATALHHSPPSAQA

PCDH11X

1226

Q9BZA7
SEQVSHHPPISAFHA

OSBPL1A

646

Q9BXW6
AHCFSHSPPRDSVSV

HGFAC

446

Q04756
RFFSEQVSHHPPISA

OSBPL6

666

Q9BZF3
AHPAVSRACSTPHVQ

ARHGAP6

811

O43182
VSPSFAHNPKRHNSA

IRS2

1161

Q9Y4H2
NSVRATVQRYPPTHH

GATA3

66

P23771
QVHASQPSSFHDFPD

APOB

3601

P04114
SHPHPAVVGINAFSS

EBF4

421

Q9BQW3
HHSKPPTASQQEVRA

C7orf57

106

Q8NEG2
AAHLPAEFTPAVHAS

HBA1;

111

P69905
NAHHRSGAQVFPESP

GNAS

66

O95467
SEEALTVHAPFPAAH

ADGRG1

61

Q9Y653
FHSPPHTAAHNASVD

ADGRG1

161

Q9Y653
AQEPHRHSTFIPGTN

LPA

1746

P08519
QRHTPQSPFTNHAAA

C17orf80

436

Q9BSJ5
PASPSHETGAFAHAR

MARK1

631

Q9P0L2
SSAASASPHQPIVIH

MAST4

1131

O15021
EAHISHFIHNVPFPS

DENND4B

351

O75064
VFHPGISSNHTDDSP

IDS

136

P22304
EHPQESTHEAFPASV

CCDC168

3256

Q8NDH2
THAEETPNQPFNSVH

CUZD1

556

Q86UP6
PSHEFQQVALHPART

LINC01554

51

Q52M75
NHTAHPSGVFSEQVP

ERVFC1

276

P60507
RASDPAAYVSHLPVH

POLRMT

906

O00411
TVRFVAEQVSHHPPV

OSBPL11

501

Q9BXB4
VSHHPPVSAFHVSNR

OSBPL5

476

Q9H0X9
PIAVTHFLHNSANVP

USO1

506

O60763
SATHQFVHTFQSPEP

LMBRD2

346

Q68DH5
VSAHQHPATARSPRA

OPLAH

591

O14841
HPTPISTEANRVEAH

NCAN

646

O14594
NPVFAHSTVVHPESR

PTCH1

1261

Q13635
HQHPRTSEDTVGTFA

SHROOM2

781

Q13796
FGHSVETPHIRAEPS

SGCZ

176

Q96LD1
AAQEPHRHSIFTPET

PLG

506

P00747
HRHSIFTPETNPRAG

PLG

511

P00747
EHDVPHQPFSQAVLS

DIS3

436

Q9Y2L1
FISEQVSHHPPISAF

OSBPL2

171

Q9H1P3
VSHHDPEVPFNHSFI

SCARF1

496

Q14162
LSPHFPHTAALDQAV

RRP12

521

Q5JTH9
FATESSFDPHHRAQP

SHANK1

856

Q9Y566
PLPVSAASQAHQASH

ATF6B

681

Q99941
DVFIHQANHPLTVPS

C11orf40

66

Q8WZ69
HAPPAATLRRTHTFN

SEMA6B

836

Q9H3T3
GHREPSAHPVEVFSF

TMEM175

236

Q9BSA9
HYHLPVARATAPVQS

SPEN

3161

Q96T58
TPAVHSDFVSGVSPH

RP1L1

741

Q8IWN7
ASANPADHRVHQVTP

PITHD1

191

Q9GZP4
SHAPLHSVTNSPEVA

ZDBF2

876

Q9HCK1
EAPVSHHAATERTSP

SPTB

2101

P11277
AEPAEPHTHRTAEAQ

ZNF469

3886

Q96JG9
ALQANHSVPDVAHPV

ZNF536

241

O15090
VTSPRSEHYAAPQLH

ZIC1

181

Q15915
HRRTAHSPASATHPF

ZNF526

291

Q8TF50
TLPAHSDPVSAVHFN

WDR5

166

P61964
PEADQHQPFLFRHAS

WNK4

561

Q96J92
THRPHPTSICDNFSA

TOE1

291

Q96GM8
VTHSDPPRAHAHSLV

NFKB2

96

Q00653