Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

4.08e-1238497GO:0000146
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

1.47e-08118497GO:0003774
GeneOntologyMolecularFunctionactin binding

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 ENC1 TMOD1 MYH15 DMD MYO5C

1.73e-084794911GO:0003779
GeneOntologyMolecularFunctioncytoskeletal protein binding

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 ENC1 SORBS3 TMOD1 MYH15 MTCL1 DMD KATNA1 TBCC MYO5C

3.15e-0810994915GO:0008092
GeneOntologyMolecularFunctionactin filament binding

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

7.45e-08227498GO:0051015
GeneOntologyMolecularFunctioncalmodulin binding

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

1.40e-06230497GO:0005516
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 MYH4 MYH6 MYH8 MYH13 IGHMBP2 NAV1 MYH15 KATNA1 MYO5C

1.96e-066144910GO:0140657
GeneOntologyMolecularFunctionstructural constituent of muscle

TPM1 MYH8 DMD

1.60e-0443493GO:0008307
GeneOntologyMolecularFunctionguanylate cyclase activity

GUCY2F GUCY2D

2.62e-0410492GO:0004383
GeneOntologyMolecularFunctionvinculin binding

SORBS3 DMD

4.52e-0413492GO:0017166
GeneOntologyMolecularFunctionadenylate cyclase activity

GUCY2F GUCY2D

8.80e-0418492GO:0004016
GeneOntologyMolecularFunctioncyclase activity

GUCY2F GUCY2D

1.57e-0324492GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

GUCY2F GUCY2D

1.71e-0325492GO:0016849
GeneOntologyBiologicalProcessmuscle filament sliding

TPM1 MYH4 MYH6 MYH8

3.76e-0815494GO:0030049
GeneOntologyBiologicalProcessactin-myosin filament sliding

TPM1 MYH4 MYH6 MYH8

8.39e-0818494GO:0033275
GeneOntologyBiologicalProcessmuscle contraction

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 TMOD1 DMD

4.20e-06400498GO:0006936
GeneOntologyBiologicalProcessactin filament-based movement

TPM1 MYH4 MYH6 MYH8 MYO5C

3.08e-05153495GO:0030048
GeneOntologyBiologicalProcessmuscle system process

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 TMOD1 DMD

4.02e-05547498GO:0003012
GeneOntologyBiologicalProcessstriated muscle cell development

TPM1 MYH6 TMOD1 DMD

5.92e-0589494GO:0055002
GeneOntologyBiologicalProcesspurine-containing compound metabolic process

DIP2A MYH4 MYH6 MYH8 GUCY2F CARMIL1 GUCY2D SARM1

1.37e-04652498GO:0072521
GeneOntologyBiologicalProcessactin filament capping

TPM1 CARMIL1 TMOD1

1.78e-0446493GO:0051693
GeneOntologyBiologicalProcessactin-mediated cell contraction

TPM1 MYH4 MYH6 MYH8

2.34e-04127494GO:0070252
GeneOntologyBiologicalProcessregulation of opsin-mediated signaling pathway

GUCY2F GUCY2D

2.46e-0410492GO:0022400
GeneOntologyBiologicalProcessactomyosin structure organization

TPM1 MYH6 CARMIL1 SORBS3 TMOD1

2.52e-04239495GO:0031032
GeneOntologyBiologicalProcessnegative regulation of actin filament depolymerization

TPM1 CARMIL1 TMOD1

2.57e-0452493GO:0030835
GeneOntologyBiologicalProcesscGMP biosynthetic process

GUCY2F GUCY2D

3.59e-0412492GO:0006182
GeneOntologyBiologicalProcessreceptor guanylyl cyclase signaling pathway

GUCY2F GUCY2D

3.59e-0412492GO:0007168
GeneOntologyBiologicalProcesspositive regulation of stress fiber assembly

TPM1 CARMIL1 SORBS3

3.73e-0459493GO:0051496
GeneOntologyBiologicalProcessregulation of actin filament depolymerization

TPM1 CARMIL1 TMOD1

4.12e-0461493GO:0030834
GeneOntologyBiologicalProcessG protein-coupled opsin signaling pathway

GUCY2F GUCY2D

4.24e-0413492GO:0016056
GeneOntologyBiologicalProcesscellular component assembly involved in morphogenesis

TPM1 MAG MYH6 TMOD1

5.12e-04156494GO:0010927
GeneOntologyBiologicalProcesscellular anatomical entity morphogenesis

TPM1 MAG MYH6 TMOD1

5.12e-04156494GO:0032989
GeneOntologyBiologicalProcessactin filament depolymerization

TPM1 CARMIL1 TMOD1

5.19e-0466493GO:0030042
GeneOntologyBiologicalProcesspositive regulation of actin filament bundle assembly

TPM1 CARMIL1 SORBS3

5.91e-0469493GO:0032233
GeneOntologyBiologicalProcesspurine nucleotide metabolic process

DIP2A MYH4 MYH6 MYH8 GUCY2F GUCY2D SARM1

6.09e-04619497GO:0006163
GeneOntologyBiologicalProcessnegative regulation of actin filament polymerization

TPM1 CARMIL1 TMOD1

7.54e-0475493GO:0030837
GeneOntologyBiologicalProcesscGMP metabolic process

GUCY2F GUCY2D

9.21e-0419492GO:0046068
GeneOntologyBiologicalProcessphototransduction, visible light

GUCY2F GUCY2D

1.02e-0320492GO:0007603
GeneOntologyBiologicalProcessnucleotide metabolic process

DIP2A MYH4 MYH6 MYH8 GUCY2F GUCY2D SARM1

1.09e-03684497GO:0009117
GeneOntologyBiologicalProcessmyofibril assembly

TPM1 MYH6 TMOD1

1.12e-0386493GO:0030239
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

DIP2A MYH4 MYH6 MYH8 GUCY2F GUCY2D SARM1

1.16e-03691497GO:0006753
GeneOntologyBiologicalProcessnegative regulation of protein depolymerization

TPM1 CARMIL1 TMOD1

1.24e-0389493GO:1901880
GeneOntologyBiologicalProcessactin filament-based process

TPM1 MYH4 MYH6 MYH8 CARMIL1 SORBS3 TMOD1 MYO5C

1.28e-03912498GO:0030029
GeneOntologyBiologicalProcesspurine ribonucleotide metabolic process

DIP2A MYH4 MYH6 MYH8 GUCY2F GUCY2D

1.29e-03512496GO:0009150
GeneOntologyBiologicalProcessnegative regulation of protein polymerization

TPM1 CARMIL1 TMOD1

1.32e-0391493GO:0032272
GeneOntologyBiologicalProcesscyclic nucleotide biosynthetic process

GUCY2F GUCY2D

1.35e-0323492GO:0009190
GeneOntologyCellularComponentmyosin filament

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

2.07e-1125496GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

4.38e-1128496GO:0016460
GeneOntologyCellularComponentmyosin complex

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

7.73e-1159497GO:0016459
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH4 MYH6 MYH8 MYH13

2.46e-1016495GO:0005859
GeneOntologyCellularComponentmyofibril

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 TMOD1 MYH15 DMD

1.26e-08273499GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 TMOD1 MYH15 DMD

2.12e-08290499GO:0043292
GeneOntologyCellularComponentsupramolecular fiber

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 CARMIL1 SARM1 NAV1 TMOD1 MYH15 MTCL1 DMD KATNA1 TBCC

4.37e-0811794915GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 CARMIL1 SARM1 NAV1 TMOD1 MYH15 MTCL1 DMD KATNA1 TBCC

4.78e-0811874915GO:0099081
GeneOntologyCellularComponentactin cytoskeleton

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 CARMIL1 TMOD1 MYH15 MYO5C

7.29e-075764910GO:0015629
GeneOntologyCellularComponentsarcomere

TPM1 MYH1 MYH4 MYH6 MYH8 TMOD1 DMD

1.75e-06249497GO:0030017
GeneOntologyCellularComponentphotoreceptor cell cilium

GUCY2F CDHR1 GUCY2D PCDHB15 TBCC

1.82e-05139495GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

GUCY2F CDHR1 GUCY2D PCDHB15 TBCC

2.89e-05153495GO:0097731
GeneOntologyCellularComponentnon-motile cilium

GUCY2F CDHR1 GUCY2D PCDHB15 TBCC

9.39e-05196495GO:0097730
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

TPM1 CARMIL1 SARM1 NAV1 TMOD1 MTCL1 DMD KATNA1 TBCC

2.11e-04899499GO:0099513
GeneOntologyCellularComponentcell projection membrane

TPM1 CDHR1 PIEZO1 SLC26A4 GUCY2D DMD

4.90e-04431496GO:0031253
GeneOntologyCellularComponentphotoreceptor outer segment membrane

CDHR1 GUCY2D

8.97e-0419492GO:0042622
GeneOntologyCellularComponentphotoreceptor disc membrane

GUCY2F GUCY2D

1.69e-0326492GO:0097381
GeneOntologyCellularComponentstriated muscle thin filament

TPM1 TMOD1

1.82e-0327492GO:0005865
GeneOntologyCellularComponentphotoreceptor outer segment

GUCY2F CDHR1 GUCY2D

2.25e-03111493GO:0001750
GeneOntologyCellularComponentmyofilament

TPM1 TMOD1

2.55e-0332492GO:0036379
GeneOntologyCellularComponentnuclear outer membrane

GUCY2F GUCY2D

3.97e-0340492GO:0005640
GeneOntologyCellularComponentorganelle outer membrane

GUCY2F GUCY2D SARM1 DMD

4.11e-03279494GO:0031968
GeneOntologyCellularComponentouter membrane

GUCY2F GUCY2D SARM1 DMD

4.21e-03281494GO:0019867
GeneOntologyCellularComponentaxon

MAG PPFIA2 IGHMBP2 SARM1 NAV1 DMD KATNA1

4.50e-03891497GO:0030424
GeneOntologyCellularComponentactin filament

TPM1 CARMIL1 TMOD1

4.86e-03146493GO:0005884
GeneOntologyCellularComponentphotoreceptor connecting cilium

PCDHB15 TBCC

5.67e-0348492GO:0032391
GeneOntologyCellularComponentpresynaptic cytosol

ERC1 PPFIA2

5.90e-0349492GO:0099523
HumanPhenoIncreased left ventricular end-diastolic volume

TPM1 MYH6 DMD

1.30e-0523113HP:0033755
HumanPhenoAbnormal left ventricular end-diastolic volume

TPM1 MYH6 DMD

1.30e-0523113HP:0033754
MousePhenomyocardium necrosis

MYH6 IGHMBP2 DMD

2.58e-0521393MP:0006085
MousePhenocardiac muscle necrosis

MYH6 IGHMBP2 DMD

3.90e-0524393MP:0010632
MousePhenoeffusion

TPM1 UBR5 PIEZO1 IGHMBP2 TMOD1

6.08e-05152395MP:0021205
MousePhenoskeletal muscle fiber atrophy

MYH4 IGHMBP2 DMD

6.98e-0529393MP:0009413
MousePhenodecreased grip strength

MYH1 MYH4 PPP2R3A SLC26A4 IGHMBP2 FBXO41 NAV1 DMD

1.55e-04575398MP:0010053
MousePhenoincreased variability of skeletal muscle fiber size

MYH4 IGHMBP2 DMD

2.29e-0443393MP:0009403
MousePhenoimpaired skeletal muscle contractility

MYH1 MYH4 DMD

2.46e-0444393MP:0002841
MousePhenopericardial effusion

TPM1 UBR5 PIEZO1 TMOD1

2.50e-04111394MP:0005312
MousePhenoskeletal muscle atrophy

MYH4 IGHMBP2 DMD

4.51e-0454393MP:0009417
MousePhenodecreased skeletal muscle mass

MYH1 MYH4 IGHMBP2 DMD

4.70e-04131394MP:0004819
MousePhenomuscle degeneration

MYH4 IGHMBP2 DMD

4.76e-0455393MP:0000749
MousePhenoprolonged P wave

IGHMBP2 DMD

4.92e-0412392MP:0004071
MousePhenoabnormal cardiac output

MYH6 TMOD1 DMD

5.02e-0456393MP:0001627
MousePhenoabnormal gait

MAG MYH4 PPFIA2 SLC26A4 IGHMBP2 FBXO41 DMD

5.17e-04520397MP:0001406
DomainMyosin_N

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

3.46e-1515497IPR004009
DomainMyosin_N

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

3.46e-1515497PF02736
DomainMyosin-like_IQ_dom

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

2.69e-1419497IPR027401
Domain-

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

2.69e-14194974.10.270.10
DomainMyosin_tail_1

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

4.30e-1218496PF01576
DomainMyosin_tail

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

4.30e-1218496IPR002928
DomainMYOSIN_MOTOR

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

6.49e-1238497PS51456
DomainMyosin_head

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

6.49e-1238497PF00063
DomainMyosin_head_motor_dom

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

6.49e-1238497IPR001609
DomainMYSc

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

6.49e-1238497SM00242
DomainIQ

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 MYO5C

4.37e-0993497PS50096
DomainIQ

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

2.99e-0871496PF00612
DomainIQ

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

6.64e-0881496SM00015
DomainIQ_motif_EF-hand-BS

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

1.25e-0790496IPR000048
DomainP-loop_NTPase

MYH1 MYH4 MYH6 MYH8 MYH13 IGHMBP2 NAV1 MYH15 KATNA1 MYO5C

5.79e-058484910IPR027417
DomainHNOBA

GUCY2F GUCY2D

1.00e-046492PF07701
DomainHNOB_dom_associated

GUCY2F GUCY2D

1.00e-046492IPR011645
DomainA/G_cyclase_CS

GUCY2F GUCY2D

8.94e-0417492IPR018297
DomainNucleotide_cyclase

GUCY2F GUCY2D

1.00e-0318492IPR029787
Domain-

GUCY2F GUCY2D

1.00e-03184923.30.70.1230
DomainGUANYLATE_CYCLASE_2

GUCY2F GUCY2D

1.12e-0319492PS50125
DomainGUANYLATE_CYCLASE_1

GUCY2F GUCY2D

1.12e-0319492PS00452
DomainA/G_cyclase

GUCY2F GUCY2D

1.12e-0319492IPR001054
DomainCYCc

GUCY2F GUCY2D

1.12e-0319492SM00044
DomainGuanylate_cyc

GUCY2F GUCY2D

1.12e-0319492PF00211
DomainANF_receptor

GUCY2F GUCY2D

4.24e-0337492PF01094
DomainANF_lig-bd_rcpt

GUCY2F GUCY2D

4.24e-0337492IPR001828
DomainPeripla_BP_I

GUCY2F GUCY2D

4.70e-0339492IPR028082
DomainSAM_2

PPFIA2 SARM1

5.69e-0343492PF07647
DomainAAA+_ATPase

IGHMBP2 NAV1 KATNA1

6.38e-03144493IPR003593
DomainAAA

IGHMBP2 NAV1 KATNA1

6.38e-03144493SM00382
Domain-

CARMIL1 LRRC10B FBXO41 TMOD1

9.88e-033214943.80.10.10
PathwayKEGG_VIRAL_MYOCARDITIS

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 DMD

3.30e-1070357M12294
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

TPM1 MYH6 MYH8 TMOD1 DMD

2.16e-0835355MM15005
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

TPM1 MYH6 MYH8 TMOD1 DMD

2.50e-0836355M18647
PathwayWP_STRIATED_MUSCLE_CONTRACTION_PATHWAY

TPM1 MYH6 MYH8 TMOD1 DMD

3.31e-0838355M39549
PathwayKEGG_TIGHT_JUNCTION

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

7.81e-07132356M11355
PathwayREACTOME_MUSCLE_CONTRACTION

TPM1 MYH6 MYH8 SORBS3 TMOD1 DMD

2.88e-06165356MM15026
PathwayREACTOME_MUSCLE_CONTRACTION

TPM1 MYH6 MYH8 SORBS3 TMOD1 DMD

9.49e-06203356M5485
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

TPM1 MYH6 DMD

1.12e-0383353M8728
PathwayKEGG_DILATED_CARDIOMYOPATHY

TPM1 MYH6 DMD

1.42e-0390353M835
PathwayPID_RHODOPSIN_PATHWAY

GUCY2F GUCY2D

1.47e-0323352M204
PathwayPID_CONE_PATHWAY

GUCY2F GUCY2D

1.47e-0323352M117
PathwayREACTOME_THE_PHOTOTRANSDUCTION_CASCADE

GUCY2F GUCY2D

2.66e-0331352MM14896
PathwayREACTOME_THE_PHOTOTRANSDUCTION_CASCADE

GUCY2F GUCY2D

3.20e-0334352M27183
PathwayWP_13Q1212_COPY_NUMBER_VARIATION

MAG DMD

3.20e-0334352M48103
PathwayREACTOME_SMOOTH_MUSCLE_CONTRACTION

TPM1 SORBS3

3.38e-0335352MM15114
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH1 MYH4 MYH8 MYH13

5.66e-11650410077619
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH1 MYH4 MYH6 MYH8 DMD

1.29e-102250524301466
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH1 MYH4 MYH8 MYH13

1.32e-10750435210422
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH1 MYH4 MYH6 MYH8

1.32e-10750416819597
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH1 MYH4 MYH6 MYH8

2.63e-1085043864153
Pubmed

Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

MYH1 MYH4 MYH13

1.12e-08450310388558
Pubmed

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

MYH1 MYH4 MYH8

1.12e-0845031985022
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH1 MYH4 MYH8

2.79e-0855036196357
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH1 MYH4 MYH8

2.79e-0855033829126
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH1 MYH4 MYH8

2.79e-08550312919077
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH1 MYH4 MYH8

5.57e-0865031728586
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH1 MYH4 MYH8

5.57e-08650310588881
Pubmed

Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex.

MYH1 MYH4 DMD

1.56e-07850336200826
Pubmed

A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.

MYH1 MYH4 MYH6

1.56e-07850314667415
Pubmed

Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.

MYH1 MYH4 MYH8 DMD

2.99e-073950438690566
Pubmed

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.

MYH1 MYH4 MYH8

3.33e-071050319506036
Pubmed

Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.

MYH1 MYH4 MYH8

4.58e-07115038136524
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

TPM1 MYH6 MYH13

6.09e-07125038424456
Pubmed

TAF7L modulates brown adipose tissue formation.

MYH1 MYH4 MYH6

7.92e-071350324876128
Pubmed

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

MYH1 MYH4 MYH8

7.92e-07135038404542
Pubmed

Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.

MYH1 MYH4 MYH6

1.01e-061450324938781
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH1 MYH4 MYH8

1.01e-061450327184118
Pubmed

MusTRD can regulate postnatal fiber-specific expression.

TPM1 MYH1 MYH4

1.55e-061650316494860
Pubmed

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.

MYH1 MYH4 MYH6

1.55e-061650319922871
Pubmed

Tropomyosin requires an intact N-terminal coiled coil to interact with tropomodulin.

TPM1 TMOD1

2.03e-06250211964245
Pubmed

Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.

GUCY2F GUCY2D

2.03e-0625027777544
Pubmed

Five skeletal myosin heavy chain genes are organized as a multigene complex in the human genome.

MYH4 MYH8

2.03e-0625028518795
Pubmed

Pendred Syndrome, or Not Pendred Syndrome? That Is the Question.

SLC26A4 MYO5C

2.03e-06250234680964
Pubmed

Growth and muscle defects in mice lacking adult myosin heavy chain genes.

MYH1 MYH4

2.03e-0625029382868
Pubmed

Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.

MYH1 MYH4

2.03e-06250211150240
Pubmed

The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors.

GUCY2F GUCY2D

2.03e-06250217255100
Pubmed

Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.

MYH1 MYH4

2.03e-06250211744674
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

PCNX4 PPFIA2 ZNF451 FBXO41 DMD

2.61e-0615150517043677
Pubmed

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.

TPM1 MYH1 MYH4 MYH6 MYH8

2.97e-0615550522673621
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TPM1 MAG DIP2A MYH6 ERC1 PPFIA2 CARMIL1 FBXO41 NAV1 TMOD1 DMD

4.69e-061431501137142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 ERC1 PPFIA2 UTP14A MYH15 DMD

5.04e-061442501135575683
Pubmed

A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.

GUCY2F CDHR1 GUCY2D DKK3

5.79e-068150416110338
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH4

6.07e-06350226059207
Pubmed

Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter.

MYH6 DMD

6.07e-06350231857666
Pubmed

Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.

MYH1 MYH4

6.07e-06350236515178
Pubmed

Localization of the binding interface between leiomodin-2 and α-tropomyosin.

TPM1 TMOD1

6.07e-06350226873245
Pubmed

Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase.

GUCY2F GUCY2D

6.07e-06350234537244
Pubmed

Specific isomyosin proportions in hyperexcitable and physiologically denervated mouse muscle.

MYH4 DMD

6.07e-06350215013776
Pubmed

N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin.

TPM1 TMOD1

6.07e-0635028886980
Pubmed

Synemin acts as a regulator of signalling molecules during skeletal muscle hypertrophy.

MYH4 MYH8 DMD

8.93e-062850325179606
Pubmed

RD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.

GUCY2F GUCY2D

1.21e-05450221078983
Pubmed

Retinal guanylyl cyclase isozyme 1 is the preferential in vivo target for constitutively active GCAP1 mutants causing congenital degeneration of photoreceptors.

GUCY2F GUCY2D

1.21e-05450222623665
Pubmed

Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development.

MYH1 DMD

1.21e-05450228569755
Pubmed

The kinase homology domain of retinal guanylyl cyclases 1 and 2 specifies the affinity and cooperativity of interaction with guanylyl cyclase activating protein-2.

GUCY2F GUCY2D

1.21e-0545029698373
Pubmed

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.

MYH1 MYH8

1.21e-05450220357587
Pubmed

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.

MYH1 MYH4

1.21e-05450211023856
Pubmed

Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder.

TPM1 TMOD1

1.21e-05450215095301
Pubmed

Contractile protein mutations and heart disease.

TPM1 MYH6

1.21e-0545028791411
Pubmed

Localization of dystrophin gene transcripts during mouse embryogenesis.

MYH6 DMD

1.21e-0545021429837
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH1 MYH4

1.21e-05450211029314
Pubmed

Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.

MYH4 MYH15

1.21e-05450219948655
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH1 MYH4

1.21e-05450218417546
Pubmed

Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.

MYH1 MYH4

1.21e-05450212547197
Pubmed

Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.

MYH1 MYH4 MYH6

1.22e-053150321985497
Pubmed

Dilated Cardiomyopathy Overview

TPM1 MYH6 DMD

1.35e-053250320301486
Pubmed

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development.

MYH1 MYH4 MYH8

1.48e-053350332094117
Pubmed

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

TPM1 TMOD1 DMD

1.62e-053450331024170
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CNNM3 PRR14 PPP2R3A UBR5 PPFIA2 MTCL1 CEP43

1.72e-0557350728330616
Pubmed

Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.

MYH1 MYH4

2.02e-05550230737693
Pubmed

Piezo1 regulates the regenerative capacity of skeletal muscles via orchestration of stem cell morphological states.

PIEZO1 DMD

2.02e-05550235302846
Pubmed

Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.

GUCY2F GUCY2D

2.02e-05550223082185
Pubmed

Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors.

GUCY2F GUCY2D

2.02e-05550221598940
Pubmed

Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy.

TPM1 MYH6

2.02e-05550220215591
Pubmed

Retinal guanylyl cyclase activation by calcium sensor proteins mediates photoreceptor degeneration in an rd3 mouse model of congenital human blindness.

GUCY2F GUCY2D

2.02e-05550231346032
Pubmed

Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein.

GUCY2F GUCY2D

2.02e-05550227471269
Pubmed

A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.

MYH1 MYH4

3.03e-05650220417199
Pubmed

A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.

MYH1 MYH4

3.03e-05650217559643
Pubmed

Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo.

TPM1 TMOD1

3.03e-05650224500875
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 UBR5

3.72e-0564750726618866
Pubmed

HOXA5 plays tissue-specific roles in the developing respiratory system.

MYH1 MYH4 MYH8

4.06e-054650328827394
Pubmed

A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation.

MYH4 MYH8

4.23e-05750210075840
Pubmed

ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.

MYH1 MYH4

4.23e-05750229758057
Pubmed

Chromosomal localization and genomic organization of genes encoding guanylyl cyclase receptors expressed in olfactory sensory neurons and retina.

GUCY2F GUCY2D

4.23e-0575028838319
Pubmed

Global/temporal gene expression in diaphragm and hindlimb muscles of dystrophin-deficient (mdx) mice.

MYH4 DMD

4.23e-05750212176734
Pubmed

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

MYH1 MYH8 DMD

5.22e-055050327597886
Pubmed

Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.

MYH1 MYH4

5.64e-05850226993635
Pubmed

Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development.

MYH1 MYH4

5.64e-05850233667029
Pubmed

Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy.

TPM1 MYH6

5.64e-05850228659827
Pubmed

Subtractive cDNA cloning as a tool to analyse secondary effects of a muscle disease. Characterization of affected genes in the myotonic ADR mouse.

TPM1 MYH4

5.64e-0585027522680
Pubmed

GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.

MYH1 MYH4

7.25e-05950231960486
Pubmed

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.

MYH6 TMOD1

7.25e-05950226487682
Pubmed

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

ERC1 PPFIA2

7.25e-05950212923177
Pubmed

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.

MYH1 MYH4 MYH8

8.16e-055850321884692
Pubmed

The expression of myosin genes in developing skeletal muscle in the mouse embryo.

MYH4 MYH8

9.05e-05105022211821
Pubmed

Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.

MYH1 MYH8

9.05e-05105028950513
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

TPM1 UBR5 ERC1 IGHMBP2 SARM1 TMOD1 CEP43

9.72e-0575450733060197
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

MYH1 MYH4

1.10e-041150238303699
Pubmed

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.

MYH1 MYH4

1.10e-041150218310078
Pubmed

The histone code reader Spin1 controls skeletal muscle development.

MYH1 MYH4

1.10e-041150229168801
Pubmed

Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.

MYH1 MYH4

1.10e-041150216024798
Pubmed

Molecular diversity of myofibrillar proteins: gene regulation and functional significance.

TPM1 TMOD1

1.32e-04125028618961
Pubmed

The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.

MYH1 MYH8

1.56e-04135028948582
Pubmed

Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors.

ERC1 CDHR1

1.56e-041350236179691
Pubmed

Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness.

MYH1 DMD

1.82e-041450228153048
Pubmed

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.

MYH1 MYH4

1.82e-041450233742095
InteractionSTK4 interactions

MYH1 MYH6 MYH8 MYH13 ERC1 MYH15 CEP43

1.08e-07159497int:STK4
InteractionMYH8 interactions

TPM1 MYH4 MYH6 MYH8 MYH13

1.64e-0752495int:MYH8
InteractionLZTR1 interactions

MYH1 MYH4 MYH6 MYH8 MYH13 ZNF451

2.81e-07111496int:LZTR1
InteractionTSPAN33 interactions

MYH1 MYH4 MYH8 MYH13 GORAB

5.10e-0765495int:TSPAN33
InteractionPRKAG2 interactions

TPM1 MYH1 MYH4 MYH6 MYH8

6.40e-0768495int:PRKAG2
InteractionRSPH6A interactions

MYH1 MYH4 MYH8 MYH13

1.36e-0634494int:RSPH6A
InteractionACTN2 interactions

TPM1 CNNM3 MYH1 MYH4 MYH6 MYH8

3.53e-06171496int:ACTN2
InteractionSTK3 interactions

MYH1 MYH6 MYH8 MYH13 MYH15 CEP43

4.90e-06181496int:STK3
InteractionCDK3 interactions

MYH1 MYH6 MYH8 MYH13 MYH15

8.29e-06114495int:CDK3
InteractionMYH4 interactions

TPM1 MYH4 MYH8 UBR5

2.97e-0573494int:MYH4
InteractionPNMA2 interactions

CNNM3 PRR14 UBR5 MTCL1 KATNA1 MYO5C

3.14e-05251496int:PNMA2
InteractionTPM1 interactions

TPM1 MYH1 MYH4 MYH6 MYH8 TMOD1

4.08e-05263496int:TPM1
InteractionHSPB8 interactions

TPM1 MYH1 MYH4 MYH6 MYH8

6.01e-05172495int:HSPB8
InteractionSBDS interactions

MYH1 MYH4 MYH8 MYH13 MTCL1

7.65e-05181495int:SBDS
InteractionMYH6 interactions

TPM1 MYH1 MYH6 MYH8

8.01e-0594494int:MYH6
InteractionASAH2 interactions

MYH1 MYH4

8.63e-056492int:ASAH2
InteractionABTB2 interactions

MYH1 MYH4 MYH6 MYH8

1.06e-04101494int:ABTB2
InteractionZSCAN5A interactions

MYH1 MYH4 MYH8

1.07e-0438493int:ZSCAN5A
InteractionGUCY2F interactions

GUCY2F GUCY2D

1.21e-047492int:GUCY2F
InteractionAURKC interactions

MYH1 MYH4 MYH8

1.56e-0443493int:AURKC
InteractionNIN interactions

PPP2R3A MYH13 ERC1 UTP14A TMOD1 CEP43

2.25e-04359496int:NIN
InteractionFBXO32 interactions

TPM1 MYH1 MYH4 MYH6 MYH8 CEP43

3.31e-04386496int:FBXO32
InteractionBICD1 interactions

PPP2R3A UBR5 ERC1 CARMIL1 NAV1

3.45e-04250495int:BICD1
InteractionGUCA1B interactions

GUCY2F GUCY2D

3.76e-0412492int:GUCA1B
InteractionKCTD13 interactions

TPM1 MAG DIP2A MYH6 ERC1 PPFIA2 CARMIL1 FBXO41 NAV1 TMOD1 DMD

4.21e-0413944911int:KCTD13
InteractionTMEM260 interactions

MYH1 MYH4

4.44e-0413492int:TMEM260
Cytoband17p13.1

MYH1 MYH4 MYH8 GUCY2D

8.03e-0611849417p13.1
CytobandEnsembl 112 genes in cytogenetic band chr17p13

MYH1 MYH4 MYH8 MYH13 GUCY2D

3.43e-05346495chr17p13
GeneFamilyMyosin heavy chains

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

4.86e-14152961098
GeneFamilyGuanylate cyclase receptors

GUCY2F GUCY2D

5.19e-057292343
GeneFamilySterile alpha motif domain containing

PPFIA2 SARM1

8.73e-0388292760
CoexpressionHUMMERICH_BENIGN_SKIN_TUMOR_DN

MYH1 MYH4 MYH8

6.84e-0620493M1123
CoexpressionHUMMERICH_BENIGN_SKIN_TUMOR_DN

MYH1 MYH4 MYH8

7.97e-0621493MM1102
CoexpressionHALLMARK_MYOGENESIS

MYH1 MYH4 MYH8 SORBS3 DMD

3.57e-05200495M5909
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH8 MYH13

7.18e-0762504a20620a8869721ea62984c2022ee1b484b455824
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH8 MYH13

7.18e-0762504ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 PPFIA2 TMOD1 DMD DKK3

8.78e-071565056365b69ede98bc866e996bc52736b00401aacf6f
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Syt15_(Medial_habenula)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH4 MYH6 MYH13

1.72e-06775047f624e9262bd0dc2ac4176f43c91a4bc0f521fe5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 GUCY2F PPFIA2 MYH15 DMD

1.98e-06184505ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 GUCY2F PPFIA2 MYH15 DMD

1.98e-061845052cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 GUCY2F PPFIA2 MYH15 DMD

1.98e-061845052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 PPFIA2 TMOD1 DMD DKK3

1.98e-06184505102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 PPFIA2 TMOD1 DMD DKK3

1.98e-06184505689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

1.18e-05125504d05556ea185c15815a4f8643f1c01185badbeece
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GORAB SARM1 ENC1 DKK3

1.75e-051385048d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

2.07e-0514450471107275767a0728541a3695715c44874b3e5efc
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

2.24e-0514750450e86860a94be103092c40e39a172eac92372f0d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

2.90e-05157504741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

3.12e-051605040bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

TPM1 PPFIA2 DMD DKK3

3.20e-0516150464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 MYH8 MTCL1

3.44e-05164504382e42701779d12a7948690b3be72d06dd75c8b4
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 LRRC10B TMOD1 DMD

3.52e-051655048a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH1 MYH4 MYH8 TMOD1

3.69e-05167504d78356bf0c473816dbabaee51984940bd822f84e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH1 MYH4 MYH8 MYH13

3.96e-051705048ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPM1 PPFIA2 TMOD1 DMD

4.24e-051735045416b092321c7d9b63f0418c60f2402a138355bf
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH1 MYH4 MYH8 LRRC10B

4.33e-051745043503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC10B SORBS3 TMOD1 DMD

4.43e-05175504316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC10B SORBS3 TMOD1 DMD

4.43e-05175504a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAG PCNX4 CARMIL1 SLC26A4

4.53e-051765046c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPM1 MYH6 MYH8 DMD

4.63e-05177504c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYH4 MYH8 MYH13

4.66e-0562503461d280a1b955033186cfc326f9ace85b4a53c54
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(Neuron.Gad1Gad2.Sst-Nr2f2)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MYH4 MYH8 MYH13

4.66e-05625039db88da996b9977f5a89afe505cd55e7b5324bc9
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 MYH8 CARMIL1 LRRC10B

4.73e-05178504f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

4.73e-0517850476e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

4.73e-051785045442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM1 MYH1 MYH4 TMOD1

4.73e-0517850469f68eeab11b088fcb1f963c92eff0f1cd0e711a
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

4.73e-0517850482f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

4.73e-05178504523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

TPM1 PPFIA2 TMOD1 DMD

4.94e-05180504d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 PIEZO1 NAV1 DKK3

4.94e-0518050412537d8a569faa69f474284d2c201475722b8ca1
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CNNM3 TMOD1 MTCL1 MYO5C

5.05e-05181504f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

TPM1 MYH6 TMOD1 DMD

5.05e-05181504719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH4 MYH8 MYH13 NAV1

5.16e-05182504fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM1 MYH6 PPP2R3A TMOD1

5.27e-05183504905e1e9be0f15be184447df04b134a6aa8279074
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM1 MYH6 PPP2R3A TMOD1

5.27e-0518350492eed783347a372b850de3189e72525082390014
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

PPFIA2 CARMIL1 MYH15 DMD

5.27e-05183504818fd886e0188091310825f9145fa53328f2c979
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 PPFIA2 DMD DKK3

5.27e-051835048a799807fbf24456a9811e0c64068187940a2f71
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PPFIA2 CARMIL1 MYH15 DMD

5.27e-05183504cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH6 MYH8

5.37e-0565503b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH6 MYH8

5.37e-05655033b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 PPFIA2 TMOD1 DMD

5.38e-05184504327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH4 MYH8 MYH13 NAV1

5.50e-051855048f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM1 MYH1 MYH4 TMOD1

5.50e-051855049245c322aae8bb9065d50dada198a5ee143a3444
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 MTCL1 DMD DKK3

5.61e-051865046add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 TMOD1 MYO5C

5.61e-05186504c7214e762b3b48197fdd0b36a50a4de2550a888f
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYH13 PPFIA2 NAV1 MYH15

5.61e-0518650423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 TMOD1 MYO5C

5.73e-05187504a5318c888b334e8695f38971a7d100b93cdaf04b
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

TPM1 PPFIA2 TMOD1 DMD

5.73e-05187504464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 TMOD1 MYO5C

5.73e-0518750464ba0df991eab8b2632751805d758c5f2711f4d7
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPM1 ENC1 MTCL1 DKK3

5.85e-05188504c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 MTCL1 DMD DKK3

5.85e-051885043177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TPM1 MTCL1 DMD DKK3

5.85e-05188504293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM1 MYH1 MYH4 TMOD1

5.97e-05189504d2b008f98739c6af7ee63b643011a240db20e4d8
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

TPM1 PPFIA2 CARMIL1 DMD

5.97e-051895046b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TPM1 TMOD1 MTCL1 DMD

5.97e-05189504da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 SORBS3 TMOD1 DMD

6.10e-051905045681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 NAV1 TMOD1 DMD

6.10e-05190504918ad5037881212008f9f69d5df5da91fd01422c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 PPFIA2 TMOD1 DMD

6.10e-05190504f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

TPM1 TMOD1 MTCL1 DKK3

6.10e-05190504645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPM1 PPFIA2 TMOD1 DMD

6.10e-05190504562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

TPM1 MYH6 PPP2R3A DMD

6.10e-05190504fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 SLC26A4 MTCL1 MYO5C

6.10e-05190504aaf5f1c1ff7b1454f4e5dacfeb48e1c3627e3372
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 SLC26A4 MTCL1 MYO5C

6.10e-05190504a20123d5c6cb8c2f0dfd99bbfdb571a73c36234d
ToppCell18-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

TPM1 MAG ENC1 MTCL1

6.22e-0519150486ce98d2c90c196474b06869de888cf5d1eed196
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPM1 MYH1 MYH4 TMOD1

6.22e-05191504f932980baa032748857cb367a55c37dd975c693e
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

TPM1 MYH6 PPP2R3A DMD

6.22e-051915045d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

6.35e-0519250413e4b17d7a592604140777aca235f795df6b3f91
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

6.35e-05192504f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 SLC26A4 MTCL1 MYO5C

6.35e-051925046244541688f85917018a057aa0b3e5972934dfbc
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 TMOD1 MTCL1 DMD

6.48e-05193504173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

TPM1 MYH6 PPP2R3A DMD

6.48e-05193504dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TPM1 ENC1 MTCL1 DMD

6.48e-05193504000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

TPM1 MYH6 PPP2R3A DMD

6.61e-05194504c3535f7cc0076653c72db582047cff053c322397
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPM1 PPFIA2 ENC1 DKK3

6.74e-0519550451db90e7611f7d69980878c046505ff34212079b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

PPP2R3A PPFIA2 ENC1 TMOD1

6.88e-051965049401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 CDHR1 PIEZO1 MYO5C

6.88e-05196504847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPM1 CDHR1 PIEZO1 MYO5C

7.01e-05197504d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 PPFIA2 TMOD1 DMD

7.01e-05197504bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 PPFIA2 TMOD1 DMD

7.15e-05198504bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CNNM3 PRR14 JADE2 TBCC

7.29e-0519950426bb93347e6722abd174dfa62cab692ce2b7eb23
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TPM1 TMOD1 DMD DKK3

7.29e-051995046b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 PPFIA2 LRRC10B DMD

7.29e-05199504c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 PPFIA2 TMOD1 DMD

7.29e-05199504b1753474152b82a0b811b9878c890a359e14919a
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

TPM1 MTCL1 DMD DKK3

7.44e-05200504593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

TPM1 TMOD1 DMD DKK3

7.44e-05200504a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm|6m / Sample Type, Dataset, Time_group, and Cell type.

TPM1 MYH8 TMOD1 DMD

7.44e-052005040f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TPM1 MTCL1 DMD DKK3

7.44e-05200504dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TPM1 TMOD1 DMD DKK3

7.44e-052005044e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPM1 PPFIA2 TMOD1 DMD

7.44e-05200504a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TPM1 MYH1 PPFIA2 DKK3

7.44e-0520050407641f476cb1a131c2a50258b88cc13bb38c8379
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TPM1 MYH1 PPFIA2 DKK3

7.44e-05200504343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TPM1 TMOD1 DMD DKK3

7.44e-0520050409537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TPM1 MTCL1 DMD DKK3

7.44e-05200504c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TPM1 TMOD1 DMD DKK3

7.44e-0520050477631c471cc5d453a749784f838cfa6408caf09b
ComputationalGenes in the cancer module 65.

GUCY2F GUCY2D

2.70e-0410272MODULE_65
ComputationalGenes in the cancer module 445.

GUCY2F GUCY2D

6.25e-0415272MODULE_445
ComputationalGenes in the cancer module 493.

TPM1 JADE2 MYO5C

6.63e-0469273MODULE_493
Drugpurealin

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

3.78e-1158497CID006419303
Drugfast white

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13

3.58e-1042496CID000024008
Drugformycin triphosphate

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

1.21e-0951496CID000122274
DrugB0683

MYH1 MYH4 MYH6 MYH8 MYH13 DMD MYO5C

5.67e-09117497CID006398969
Drugclenbuterol

MYH1 MYH4 MYH6 MYH8 MYH13 DMD MYO5C

2.18e-08142497CID000002783
DrugS-(-)-Etomoxir

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

7.40e-08100496CID000060765
Drugblebbistatin

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

1.80e-07116496CID003476986
Drugoxovanadium

MYH1 MYH4 MYH6 MYH8 MYH13 DMD

2.20e-07120496CID000024411
DrugAC1NRBPQ

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13

4.81e-07137496CID005288569
DrugAC1N9ZZC

MYH1 MYH4 MYH6 MYH8 MYH13 NAV1

7.87e-07149496CID004369374
DrugMgCl2

TPM1 MAG MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

8.16e-07354498CID000024584
DrugNSC339663

MYH1 MYH4 MYH6 MYH8 MYH13 SORBS3 MYO5C

1.03e-06250497CID000003892
DrugSM-2

MYH1 MYH4 MYH6 MYH8 MYH13

1.21e-0687495CID000486033
Drugcreatine

MYH1 MYH4 MYH6 MYH8 MYH13 DMD

3.54e-06193496CID000000586
DrugAC1L1IZ2

MYH1 MYH4 MYH6 MYH8 MYH13 GUCY2D MYO5C

3.75e-06304497CID000004795
DrugNSC107658

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

3.92e-06306497CID000002919
Drug2bq7

MYH1 MYH4 MYH6 MYH8 MYH13

6.68e-06123495CID006540267
DrugAC1LADJ6

MYH1 MYH4 MYH6 MYH8 MYH13

8.76e-06130495CID000486032
Drugpyrophosphate

MYH1 MYH4 MYH6 MYH8 MYH13 GUCY2F GUCY2D EIF5 MYO5C

9.27e-06654499CID000001023
DrugNSC611747

MYH1 MYH4 MYH6 MYH8 PPP2R3A MYH13 MYO5C

9.78e-06352497CID000002534
DrugSpermine

MYH1 MYH4 MYH8 DMD

1.03e-0563494ctd:D013096
Drugeye gene

MYH1 MYH4 MYH6 MYH8 MYH13 GUCY2F MYO5C

1.33e-05369497CID000004782
Drugcarbachol

MYH1 MYH4 MYH6 MYH8 MYH13 GUCY2F ERC1 GUCY2D MYO5C

1.39e-05688499CID000002551
Drugcandesartan cilexetil

MYH1 MYH4 MYH6 MYH8 MYH13

1.49e-05145495CID000002540
Drugcarvedilol

MYH1 MYH4 MYH6 MYH8 MYH13

2.46e-05161495CID000002585
DrugK-Cl

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 GUCY2F MYO5C

2.58e-05567498CID000004873
Drug15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A_EA

PPP2R3A JADE2 PCNX4 SORBS3 CEP43

3.78e-051764951011_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

DIP2A PPP2R3A EIF5 MTCL1 TBCC

5.30e-051894951005_DN
Drugdiphosphonate

EIF5 DMD CEP43

6.36e-0536493CID006326975
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

DIP2A ERC1 ENC1 EIF5 CEP43

6.45e-051974956930_DN
Drugtrifluoperazine

MYH1 MYH4 MYH6 MYH8 MYH13 MYO5C

6.62e-05324496CID000005566
DrugDibucaine [85-79-0]; Up 200; 11.6uM; PC3; HT_HG-U133A

REC8 MAG MYH13 SLC26A4 SARM1

6.77e-051994954068_UP
DrugLeucomisine [17946-87-1]; Up 200; 16.2uM; HL60; HT_HG-U133A

REC8 MYH6 GUCY2F JADE2 SORBS3

6.77e-051994956125_UP
Drugnocodazole

MYH1 MYH4 MYH6 MYH8 PPP2R3A MYH13 MYO5C

6.80e-05477497CID000004122
Drug4-chloroaniline

MYH1 MYH4 MYH6 MYH8 MYH13

7.26e-05202495CID000007812
Drug1H-3

MAG UBR5 IGHMBP2

7.49e-0538493CID000043849
Drugisoproterenol

MYH1 MYH4 MYH6 MYH8 MYH13 GUCY2F DMD MYO5C

8.29e-05669498CID000003779
DrugTCNB

TPM1 MYH13 TMOD1 DMD

1.25e-04119494CID000008330
DrugD-triiodothyronine

MYH1 MYH4 MYH6 MYH8 MYH13 SLC26A4

2.36e-04409496CID000000861
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0110454 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0080719 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

3.19e-1510496DOID:0111596 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

1.40e-1412496DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

1.40e-1412496DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

2.60e-1413496DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

7.55e-1415496DOID:0050646 (implicated_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

TPM1 MYH1 MYH4 MYH6 MYH8 MYH13 MYH15 DMD

8.40e-1380498DOID:12930 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

1.78e-1048496DOID:423 (implicated_via_orthology)
Diseasecardiomyopathy (implicated_via_orthology)

MYH1 MYH4 MYH6 MYH8 MYH13 MYH15

2.02e-0971496DOID:0050700 (implicated_via_orthology)
DiseaseFamilial dilated cardiomyopathy

TPM1 MYH6 DMD

5.43e-0544493C0340427
DiseaseIdiopathic hypertrophic subaortic stenosis

TPM1 MYH6

5.64e-057492C0700053
DiseaseObstructive asymmetric septal hypertrophy

TPM1 MYH6

5.64e-057492C0597124
DiseaseCardiomyopathy, Hypertrophic, Familial

TPM1 MYH6

9.65e-059492C0949658
DiseasePrimary familial hypertrophic cardiomyopathy

TPM1 MYH6

6.11e-0422492cv:C0949658
DiseaseCone-Rod Dystrophy 2

CDHR1 GUCY2D

1.07e-0329492C3489532
DiseasePrimary familial dilated cardiomyopathy

TPM1 MYH6

1.14e-0330492cv:C0340427
DiseaseCardiomyopathies

TPM1 MYH6 DMD

1.33e-03130493C0878544
DiseasePrimary dilated cardiomyopathy

TPM1 MYH6

1.46e-0334492cv:C0007193

Protein segments in the cluster

PeptideGeneStartEntry
LDREREDEIEAIISI

CDHR1

96

Q96JP9
ISLESEERGELERIL

DMD

3496

P11532
EERGELERILADLEE

DMD

3501

P11532
LRLTILELERELEEL

CCDC157

521

Q569K6
ETLELEVEVERLLHE

GORAB

281

Q5T7V8
VSRRELDLLIAEEEE

REC8

216

O95072
DDRIEELEEALRESV

ERC1

836

Q8IUD2
VEEEAELLRRSISEI

MTCL1

641

Q9Y4B5
EEEELERILRLSLTE

ANKRD13B

611

Q86YJ7
REAVAESLLLELEEV

MAG

281

P20916
LEDLIRERTEELELE

GUCY2D

831

Q02846
ELDELTLERVLEELE

JADE2

161

Q9NQC1
DLSRELEEISERLEE

MYH8

1141

P13535
VERILTTDILAEEDE

PCNX4

101

Q63HM2
EEIEELRELRILALD

LRRC10B

61

A6NIK2
LERERLLDEVEELLE

GOLGA6L19

381

H0YKK7
SDLSRELEEISERLE

MYH1

1141

P12882
LDTELDREEQAELRL

PCDHB15

196

Q9Y5E8
EDRALLLRILESIED

PPP2R3A

586

Q06190
LTLSDDLERTIEERV

EIF5

226

P55010
EEDTELRDLLVQTLE

CEP43

11

O95684
ALREELVTILEEEEE

ERICH4

81

A6NGS2
EDLIRERTEELEIEK

GUCY2F

836

P51841
EKLEVDRRLERLSEE

FBXO41

211

Q8TF61
LRISLRELELADDVD

KATNA1

391

O75449
ITVEELTEIERLEDL

CARMIL1

896

Q5VZK9
LLSSEELETEDERLV

ENC1

196

O14682
EVRESLAELELELSE

DIP2A

16

Q14689
EVRQELEDLERSLTE

DKK3

316

Q9UBP4
ERLAEEIEKLRSELD

PPFIA2

516

O75334
RLELVESLDSDEVDL

NAV1

371

Q8NEY1
RRLSEEELLEATERI

MYH15

1711

Q9Y2K3
ELDALLLEEETVDRE

PRR14

566

Q9BWN1
SDLSRELEEISERLE

MYH4

1141

Q9Y623
RIEELEEELEAERTA

MYH6

1116

P13533
LSRELEEISERLEEA

MYH6

1141

P13533
IEEIIRSEILDESED

CNNM3

441

Q8NE01
EDVELEEAIRRSLEE

ZNF451

1046

Q9Y4E5
ITEEDLEAIRLREEA

TSNARE1

411

Q96NA8
LELIETELTEEELDV

SLC26A4

756

O43511
DLLLRLTEEELQTDL

SARM1

441

Q6SZW1
ALTEEELRTLENELD

TMOD1

21

P28289
LLELERDAEVEERRS

IGHMBP2

16

P38935
SDLARELEEISERLE

MYH13

1141

Q9UKX3
IEVLLERELAELSAE

SORBS3

271

O60504
VEELLERAESVERLE

TBCC

71

Q15814
EEEILLREFEERRSL

UTP14A

416

Q9BVJ6
IIESDLERAEERAEL

TPM1

171

P09493
EEVVTLLEDLERELD

ZBED9

121

Q6R2W3
LVRETRELELEEELY

PIEZO1

2486

Q92508
EEAVILLEDLERELD

ZSCAN9

121

O15535
VLRILDTHRELEESE

THEGL

36

P0DJG4
LERDSELLRERESVL

UBR5

301

O95071
SRLTLENRDLEEELD

MYO5C

1311

Q9NQX4