Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 ZBTB43 ZNF256 ZNF629 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF664 APP ZNF649 ZNF418 ZNF417 ZNF416 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

8.37e-4314597352GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF585A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF664 ZNF418 ZNF417 ZNF416 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.52e-4014127350GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF771 SP1 ZNF135 ZFP42 ZNF219 ZNF211 ZNF497 ZNF585A ZNF48 ZNF157 ZNF473 MZF1 ZSCAN30 ZNF587 ZBTB43 ZNF256 ZNF629 ZNF432 ZNF814 ZNF621 ZKSCAN2 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF664 APP ZNF649 ZNF418 ZNF417 ZNF416 ZNF774 ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B

5.16e-2812447339GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF771 SP1 ZNF135 ZFP42 ZNF219 ZNF211 ZNF497 ZNF585A ZNF48 ZNF157 ZNF473 MZF1 ZSCAN30 ZNF587 ZBTB43 ZNF256 ZNF629 ZNF432 ZNF814 ZNF621 ZKSCAN2 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF664 APP ZNF649 ZNF418 ZNF417 ZNF416 ZNF774 ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B

1.15e-2712717339GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF771 SP1 ZFP42 ZNF585A ZNF48 ZNF473 MZF1 ZNF629 ZNF814 ZNF721 E4F1 ZNF615 ZNF229 ZNF574 ZNF71 ZNF585B

1.42e-105607316GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF771 SP1 ZFP42 ZNF585A ZNF48 ZNF473 MZF1 ZNF629 ZNF814 ZNF721 E4F1 ZNF615 ZNF229 ZNF574 ZNF71 ZNF585B

1.67e-105667316GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF219 MZF1 ZNF589 ZNF721 E4F1 ZNF418 ZNF239

1.88e-04326737GO:0001217
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF219 MZF1 ZNF589 ZNF721 E4F1 ZNF239

1.12e-03320736GO:0001227
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SP1 ZFP42 ZNF219 ZNF585A ZNF48 ZNF473 MZF1 FIZ1 ZNF629 ZNF814 ZNF721 E4F1 ZNF615 ZNF229 APP ZNF574 ZNF71 ZNF585B

1.76e-0613907518GO:0045944
GeneOntologyCellularComponentcollagen type IV trimer

COL4A2 COL4A4

1.89e-046752GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A2 COL4A4

3.51e-048752GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A2 COL4A4

3.51e-048752GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A2 COL4A4

3.51e-048752GO:0098645
Domain-

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

4.55e-6767975573.30.160.60
Domainzf-C2H2

ZNF771 SP1 ZNF133 ZNF135 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.51e-666937557PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.65e-666947557IPR013087
DomainZINC_FINGER_C2H2_2

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.32e-657757558PS50157
DomainZINC_FINGER_C2H2_1

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.53e-657777558PS00028
DomainZnf_C2H2

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.26e-648057558IPR007087
DomainZnF_C2H2

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

1.57e-648087558SM00355
DomainZnf_C2H2-like

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

5.03e-637967557IPR015880
DomainKRAB

ZNF133 ZNF135 ZNF211 ZNF585A ZNF157 ZNF473 ZNF556 ZNF337 ZNF875 ZNF587 ZNF436 ZNF589 ZNF256 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF585B ZNF554

7.80e-443587537PS50805
DomainKRAB

ZNF133 ZNF135 ZNF211 ZNF585A ZNF157 ZNF473 ZNF556 ZNF337 ZNF875 ZNF587 ZNF436 ZNF589 ZNF256 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF169 ZNF587B ZNF585B ZNF554

4.20e-423587536PF01352
DomainKRAB

ZNF133 ZNF135 ZNF211 ZNF585A ZNF157 ZNF473 ZNF556 ZNF337 ZNF875 ZNF587 ZNF436 ZNF589 ZNF256 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF169 ZNF587B ZNF585B ZNF554

1.29e-413697536SM00349
DomainKRAB

ZNF133 ZNF135 ZNF211 ZNF585A ZNF157 ZNF473 ZNF556 ZNF337 ZNF875 ZNF587 ZNF436 ZNF589 ZNF256 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF169 ZNF587B ZNF585B ZNF554

1.43e-413707536IPR001909
Domainzf-C2H2_6

ZNF771 ZNF133 ZNF135 ZNF672 ZNF211 ZNF497 ZNF48 ZNF157 ZNF473 ZNF556 ZSCAN30 ZNF587 ZNF256 ZNF432 ZNF69 ZNF814 ZNF621 ZNF721 E4F1 ZNF615 ZNF229 ZNF317 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF169 ZNF574 ZNF71 ZNF554

2.74e-373147532PF13912
Domain-

APLP2 APP

4.76e-0537523.30.1490.140
DomainAPP_amyloid_C

APLP2 APP

4.76e-053752IPR019543
DomainAmyloid_glyco_E2_domain

APLP2 APP

4.76e-053752IPR024329
DomainA4_EXTRA

APLP2 APP

4.76e-053752PS00319
DomainAmyloid_glyco_heparin-bd

APLP2 APP

4.76e-053752IPR015849
DomainAPP_Cu_bd

APLP2 APP

4.76e-053752PF12924
DomainAPP_E2

APLP2 APP

4.76e-053752PF12925
DomainAPP_amyloid

APLP2 APP

4.76e-053752PF10515
DomainAmyloid_glyco_extracell_CS

APLP2 APP

4.76e-053752IPR019744
DomainAmyloid_glyco_intracell_CS

APLP2 APP

4.76e-053752IPR019745
DomainA4_INTRA

APLP2 APP

4.76e-053752PS00320
DomainAmyloid_glyco

APLP2 APP

4.76e-053752IPR008155
DomainAmyloid_glyco_extra

APLP2 APP

4.76e-053752IPR008154
Domain-

APLP2 APP

4.76e-0537523.90.570.10
DomainAmyloid_glyco_Cu-bd

APLP2 APP

4.76e-053752IPR011178
DomainAPP_N

APLP2 APP

4.76e-053752PF02177
DomainA4_EXTRA

APLP2 APP

4.76e-053752SM00006
DomainC4

COL4A2 COL4A4

2.36e-046752SM00111
Domain-

COL4A2 COL4A4

2.36e-0467522.170.240.10
DomainCollagen_VI_NC

COL4A2 COL4A4

2.36e-046752IPR001442
DomainNC1_IV

COL4A2 COL4A4

2.36e-046752PS51403
DomainC4

COL4A2 COL4A4

2.36e-046752PF01413
DomainEGF_Lam

STAB2 MEGF6 LAMC3

3.71e-0435753SM00180
DomainLaminin_EGF

STAB2 MEGF6 LAMC3

4.74e-0438753IPR002049
DomainSCAN

MZF1 ZSCAN30 ZKSCAN2

1.48e-0356753SM00431
DomainSCAN_BOX

MZF1 ZSCAN30 ZKSCAN2

1.64e-0358753PS50804
DomainSCAN

MZF1 ZSCAN30 ZKSCAN2

1.64e-0358753PF02023
DomainSCAN_dom

MZF1 ZSCAN30 ZKSCAN2

1.64e-0358753IPR003309
DomainRetrov_capsid_C

MZF1 ZSCAN30 ZKSCAN2

1.72e-0359753IPR008916
Domain-

APLP2 APP

2.34e-03187524.10.410.10
DomainPrtase_inh_Kunz-CS

APLP2 APP

2.34e-0318752IPR020901
DomainKU

APLP2 APP

2.34e-0318752SM00131
DomainBPTI_KUNITZ_2

APLP2 APP

2.60e-0319752PS50279
DomainKunitz_BPTI

APLP2 APP

2.60e-0319752PF00014
DomainBPTI_KUNITZ_1

APLP2 APP

2.60e-0319752PS00280
DomainGrowth_fac_rcpt_

STAB2 MEGF6 ESM1 LAMC3

3.59e-03156754IPR009030
DomainKunitz_BPTI

APLP2 APP

3.81e-0323752IPR002223
DomainEGF_LAM_2

STAB2 LAMC3

6.44e-0330752PS50027
DomainEGF_LAM_1

STAB2 LAMC3

6.44e-0330752PS01248
DomainLaminin_EGF

MEGF6 LAMC3

8.69e-0335752PF00053
DomainCTDL_fold

COL4A2 COL4A4 STAB2

9.16e-03107753IPR016187
DomainEGF

TMEFF1 STAB2 MEGF6 LAMC3

1.48e-02235754SM00181
DomainEGF-like_dom

TMEFF1 STAB2 MEGF6 LAMC3

1.79e-02249754IPR000742
DomainEGF_1

TMEFF1 STAB2 MEGF6 LAMC3

1.94e-02255754PS00022
DomainEGF-like_CS

TMEFF1 STAB2 MEGF6 LAMC3

2.09e-02261754IPR013032
DomainEGF_2

TMEFF1 STAB2 MEGF6 LAMC3

2.20e-02265754PS01186
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF771 SP1 ZNF133 ZNF135 ZNF211 ZNF585A ZNF157 ZNF473 ZNF556 ZNF337 ZNF875 ZNF587 ZNF436 ZNF589 ZNF256 ZNF432 ZNF343 ZNF621 ZNF214 ZNF721 ZNF615 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF697 ZNF71 ZNF585B ZNF554

2.33e-2413875637M734
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

SP1 ZNF585A ZNF473 ZNF814 ZNF721 ZNF317 ZNF235 ZNF664 ZNF418 ZNF416 ZNF282 ZNF169 ZNF585B

7.19e-067685613MM14851
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A2 COL4A4 APP

2.10e-0514563M6487
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL4A4 MEGF6

2.61e-0515563MM14922
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

SP1 ZNF585A GTF3A ZNF473 ZNF814 ZNF721 ZNF317 ZNF235 ZNF664 ZNF418 ZNF416 ZNF282 ZNF169 ZNF585B

3.30e-0510225614MM15436
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL4A4 LAMC3

2.23e-0430563M27216
PathwayBIOCARTA_TERT_PATHWAY

SP1 MZF1

3.21e-047562MM1541
PathwayBIOCARTA_TERT_PATHWAY

SP1 MZF1

4.27e-048562M22015
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A4

6.83e-0410562M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A4

6.83e-0410562MM1560
PathwayBIOCARTA_VITCB_PATHWAY

COL4A2 COL4A4

8.33e-0411562M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A2 COL4A4

9.97e-0412562MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A2 COL4A4

1.18e-0313562MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A2 COL4A4

1.18e-0313562M12950
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A2 COL4A4

1.37e-0314562MM1458
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A2 COL4A4

1.57e-0315562M27161
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A2 COL4A4 LAMC3

1.65e-0359563M27218
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 COL4A4

2.28e-0318562M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 COL4A4

2.28e-0318562MM14882
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF211 ZNF587 ZNF589 ZNF432 ZNF721 ZNF615 ZNF229 ZNF317 ZNF235 ZNF649 ZNF417 ZNF791 ZNF587B ZNF697 ZNF554

5.36e-20181751537372979
Pubmed

Characterization and mapping of human genes encoding zinc finger proteins.

ZNF135 ZNF48 ZNF436 ZNF629 ZNF71

1.04e-09227551946370
Pubmed

Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.

ZNF135 ZNF48 ZNF436 ZNF629 ZNF71

1.04e-09227551505991
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF585A ZNF814 ZNF721 ZNF317 ZNF585B

7.21e-08497559630514
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SP1 ZNF219 GTF3A ZNF48 ZNF473 FIZ1 ZBTB43 ZNF721 ZNF235 ZNF282 ZNF239 ZNF697

1.56e-07808751220412781
Pubmed

Specific and ubiquitous expression of different Zn finger protein genes in the mouse.

ZNF585A ZNF814 ZNF585B

3.35e-0777533143103
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SP1 ZFP42 ZNF219 ZNF585A GTF3A ZNF436 ZBTB43 E4F1 ZNF275 ZNF235 ZNF585B

3.51e-07709751122988430
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A2 COL4A4 APP

1.14e-06107539136074
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF214 ZNF235 ZNF285 ZNF282

2.10e-064275434673265
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

SP1 ZFP42 ZNF219 ZNF473 ZNF556 MZF1 ZNF436 ZBTB43 E4F1 ZNF275 ZNF235

2.77e-06877751120211142
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A2 COL4A4 APP

3.45e-061475312878203
Pubmed

Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development.

APLP2 APP

4.59e-06275219710207
Pubmed

Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.

ZNF585A ZNF585B

4.59e-06275237668106
Pubmed

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity.

APLP2 APP

4.59e-0627527758106
Pubmed

Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth.

APLP2 APP

4.59e-06275218393365
Pubmed

The amyloid precursor protein and its homologues: structural and functional aspects of native and pathogenic oligomerization.

APLP2 APP

4.59e-06275221459473
Pubmed

Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex.

APLP2 APP

4.59e-06275221435241
Pubmed

Interaction of human and mouse Abeta peptides.

APLP2 APP

4.59e-06275215584916
Pubmed

Amyloid precursor protein trafficking, processing, and function.

APLP2 APP

4.59e-06275218650430
Pubmed

Keratinocytes from APP/APLP2-deficient mice are impaired in proliferation, adhesion and migration in vitro.

APLP2 APP

4.59e-06275216584729
Pubmed

AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral thrombosis.

APLP2 APP

4.59e-06275219403832
Pubmed

A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.

APLP2 APP

4.59e-06275221266574
Pubmed

Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission.

APLP2 APP

4.59e-06275218535156
Pubmed

Differential distribution of Alzheimer's amyloid precursor protein family variants in human sperm.

APLP2 APP

4.59e-06275217405931
Pubmed

Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis.

APLP2 APP

4.59e-06275224448592
Pubmed

Structures of collagen IV globular domains: insight into associated pathologies, folding and network assembly.

COL4A2 COL4A4

4.59e-06275230443360
Pubmed

The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior.

APLP2 APP

4.59e-06275226658856
Pubmed

Hippocampal network oscillations in APP/APLP2-deficient mice.

APLP2 APP

4.59e-06275223585881
Pubmed

Generation of conditional null alleles for APP and APLP2.

APLP2 APP

4.59e-06275220140888
Pubmed

A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway.

ZNF418 ZNF416

4.59e-06275233249983
Pubmed

Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissue.

APLP2 APP

4.59e-06275225098278
Pubmed

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice.

APLP2 APP

4.59e-0627529461064
Pubmed

Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons.

APLP2 APP

4.59e-06275230506868
Pubmed

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice.

APLP2 APP

4.59e-06275210526140
Pubmed

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP.

APLP2 APP

4.59e-06275221522131
Pubmed

Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2.

APLP2 APP

4.59e-06275215919150
Pubmed

The ATP-Binding Cassette Transporter-2 (ABCA2) Overexpression Modulates Sphingosine Levels and Transcription of the Amyloid Precursor Protein (APP) Gene.

ABCA2 APP

4.59e-06275226510981
Pubmed

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.

APLP2 APP

4.59e-06275215447675
Pubmed

APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses.

APLP2 APP

4.59e-06275226551565
Pubmed

Identification of a novel amyloid precursor protein processing pathway that generates secreted N-terminal fragments.

APLP2 APP

4.59e-06275222490781
Pubmed

Lack of APP and APLP2 in GABAergic Forebrain Neurons Impairs Synaptic Plasticity and Cognition.

APLP2 APP

4.59e-06275232219307
Pubmed

Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2.

APLP2 APP

4.59e-06275215689559
Pubmed

Interaction of Sp1 and APP promoter elucidates a mechanism for Pb2+ caused neurodegeneration.

SP1 APP

4.59e-06275231945313
Pubmed

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.

COL4A2 COL4A4 SP1

7.68e-06187539160753
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF771 ZNF473 ZNF436 ZNF629 ZNF275 ZNF317 ZNF664 ZNF417 ZNF587B ZNF239 ZNF574 ZNF697

9.71e-061203751229180619
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF229 ZNF235 ZNF285

1.07e-052075312743021
Pubmed

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.

APLP2 APP

1.37e-05375211050115
Pubmed

Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity.

APLP2 APP

1.37e-05375225432317
Pubmed

Regulatory elements involved in transcription of the human NeuAcalpha2,3Galbeta1,3GalNAcalpha2,6-sialyltransferase (hST6GalNAc IV) gene.

SP1 MZF1

1.37e-05375215528990
Pubmed

Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis.

APLP2 APP

1.37e-05375220693289
Pubmed

Differential role of APP and APLPs for neuromuscular synaptic morphology and function.

APLP2 APP

1.37e-05375224998676
Pubmed

Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.

APLP2 APP

1.37e-05375229018038
Pubmed

Collagen types in various layers of the human aorta and their changes with the atherosclerotic process.

COL4A2 COL4A4

1.37e-0537523089234
Pubmed

Regulation of gene expression by the APP family in the adult cerebral cortex.

APLP2 APP

1.37e-05375234997052
Pubmed

MicroRNA-153 negatively regulates the expression of amyloid precursor protein and amyloid precursor-like protein 2.

APLP2 APP

1.37e-05375222510281
Pubmed

The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.

APLP2 APP

1.37e-05375221445342
Pubmed

Amyloid precursor proteins are constituents of the presynaptic active zone.

APLP2 APP

1.37e-05375223815291
Pubmed

Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.

ABCA2 APP

1.37e-05375222086926
Pubmed

Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference.

APLP2 APP

1.37e-05375216889988
Pubmed

APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival.

APLP2 APP

1.37e-05375232891188
Pubmed

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.

APLP2 APP

1.37e-05375219126676
Pubmed

APLP2 regulates neuronal stem cell differentiation during cortical development.

APLP2 APP

1.37e-05375223345401
Pubmed

Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein.

APLP2 APP

1.37e-05375215561424
Pubmed

Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition.

APLP2 APP

1.37e-05375229661886
Pubmed

Amyloid precursor protein (APP)/APP-like protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome trafficking of glypican-1-derived heparan sulfate.

APLP2 APP

1.37e-05375224898256
Pubmed

Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes.

SP1 MZF1

1.37e-05375217851584
Pubmed

APPsα rescues impaired Ca2+ homeostasis in APP- and APLP2-deficient hippocampal neurons.

APLP2 APP

1.37e-05375234172567
Pubmed

MIR503HG impeded ovarian cancer progression by interacting with SPI1 and preventing TMEFF1 transcription.

TMEFF1 SP1

1.37e-05375235771155
Pubmed

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.

APLP2 APP

1.37e-05375215677459
Pubmed

The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Aβ fragment generation.

ABCA2 APP

1.37e-05375220704561
Pubmed

Homo- and heterodimerization of APP family members promotes intercellular adhesion.

APLP2 APP

1.37e-05375216193067
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

COL4A2 COL4A4 LAMC3

2.42e-052675324742657
Pubmed

Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.

COL4A2 COL4A4

2.75e-0547527827955
Pubmed

Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage.

APLP2 APP

2.75e-05475214983046
Pubmed

First identification of ITM2B interactome in the human retina.

APLP2 APP

2.75e-05475234446781
Pubmed

APP, APLP2 and LRP1 interact with PCSK9 but are not required for PCSK9-mediated degradation of the LDLR in vivo.

APLP2 APP

2.75e-05475228495363
Pubmed

Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease.

APLP2 APP

2.75e-05475215208260
Pubmed

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein.

APLP2 APP

2.75e-0547528855266
Pubmed

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.

APLP2 APP

2.75e-0547528894693
Pubmed

Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression.

APLP2 APP

2.75e-05475217556541
Pubmed

Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis.

ZNF418 ZNF416

2.75e-05475229065170
Pubmed

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.

APLP2 APP

2.75e-05475216314516
Pubmed

Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype.

APLP2 APP

2.75e-05475234008862
Pubmed

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP.

APLP2 APP

2.75e-05475220855613
Pubmed

Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein.

APLP2 APP

2.75e-0547529461550
Pubmed

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.

APLP2 APP

2.75e-05475210460257
Pubmed

In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.

COL4A2 COL4A4

4.57e-0557529409248
Pubmed

Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter.

APLP2 APP

4.57e-05575217709753
Pubmed

Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.

APLP2 APP

4.57e-05575210081969
Pubmed

Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1.

APLP2 APP

4.57e-05575212917434
Pubmed

APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission.

APLP2 APP

4.57e-05575228450540
Pubmed

Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors.

SP1 ABCA2

4.57e-05575212560508
Pubmed

Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling.

APLP2 APP

4.57e-05575221293490
Pubmed

High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.

SP1 ZNF219 ZNF48 ZNF239

5.25e-059475416325481
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

SP1 ZNF133 MAP1B APLP2 APP

5.99e-0519175520195357
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A2 COL4A4

6.84e-0567529506531
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A2 COL4A4

6.84e-0567527495302
Pubmed

The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance.

APLP2 APP

6.84e-05675228785723
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A2 COL4A4

6.84e-0567522426947
Pubmed

Computer sequence analysis of human highly conserved zinc finger modules.

ZNF587 ZNF587B

6.84e-05675210520746
InteractionNOTCH2 interactions

ZNF771 SP1 ZNF219 ZNF672 ZNF497 ZNF48 FIZ1 ZNF629 ZKSCAN2 E4F1 ZNF275 ZNF317 ZNF235 ZNF664 ZNF649 ZNF417 ZNF282 ZNF791 ZNF587B ZNF574

4.91e-174237520int:NOTCH2
InteractionTRIM41 interactions

ZNF219 ZNF497 ZNF48 ZNF473 ZNF587 ZNF629 ZNF343 ZNF275 APP ZNF417 ZNF169 ZNF574 ZNF71

1.82e-122237513int:TRIM41
InteractionTRIM28 interactions

ZNF133 ZFP42 ZNF211 MAP1B ZNF587 ZNF589 ZNF256 ZNF432 ZNF621 ZNF721 ZNF615 ZNF229 ZNF317 ZNF235 ZNF649 ZNF418 ZNF417 ZNF416 ZNF791 ZNF169 ZNF587B ZNF697 ZNF585B ZNF554

3.10e-1014747524int:TRIM28
InteractionLTBP2 interactions

ZNF497 ZKSCAN2 E4F1 ZNF664 ZNF417 ZNF282 ZNF791 ZNF574

9.59e-1085758int:LTBP2
InteractionKRTAP10-7 interactions

ZNF133 ZNF337 ZNF587 ZNF256 E4F1 APP ZNF418 ZNF417 ZNF774 ZNF169 ZNF697

1.09e-082937511int:KRTAP10-7
InteractionZNF467 interactions

ZNF211 ZNF48 ZNF629 ZNF721 ZNF317 ZNF791 ZNF587B ZNF574

3.36e-07179758int:ZNF467
InteractionZNF792 interactions

ZNF497 ZNF48 ZNF473 ZNF275 ZNF71

2.90e-0660755int:ZNF792
InteractionKRTAP10-9 interactions

ZNF497 ZNF473 ZNF587 ZNF275 ZNF317 ZNF417 ZNF774 ZNF697

3.15e-06241758int:KRTAP10-9
InteractionCCDC125 interactions

ZNF337 ZNF587 ZNF436 ZNF343 ZNF417

5.03e-0667755int:CCDC125
InteractionCENPB interactions

ZNF214 APP ZNF418 ZNF416 ZNF169 ZNF574

6.84e-06124756int:CENPB
InteractionZNF837 interactions

ZNF497 ZNF473 ZNF587 ZNF275 ZNF417

1.13e-0579755int:ZNF837
InteractionKRTAP10-6 interactions

ZNF672 ZNF418 ZNF774 ZNF169 ZNF239

1.92e-0588755int:KRTAP10-6
InteractionRPL26L1 interactions

ZNF48 MAP1B E4F1 ZNF275 ZNF317 APP ZNF169 ZNF574 ZNF71

3.10e-05431759int:RPL26L1
InteractionGZF1 interactions

ZNF473 E4F1 ZNF169 ZNF697 ZNF71

4.11e-05103755int:GZF1
InteractionTRIM39 interactions

ZNF556 ZNF621 ZNF214 APP ZNF416

5.16e-05108755int:TRIM39
InteractionZNF417 interactions

ZNF587 ZBTB43 ZNF69 ZNF417 ZNF774 ZNF71

5.30e-05178756int:ZNF417
InteractionOSM interactions

COL4A2 COL4A4 APP

5.39e-0520753int:OSM
InteractionZNF473 interactions

ZNF497 ZNF473 MZF1 APP

5.61e-0556754int:ZNF473
InteractionBEGAIN interactions

ZNF587 APP ZNF417 ZNF774

6.90e-0559754int:BEGAIN
InteractionVWC2 interactions

ZNF497 ZNF587 ZNF417 ZNF774

8.38e-0562754int:VWC2
InteractionSMARCAD1 interactions

ZFP42 ZNF211 ZNF214 ZNF235 ZNF649 ZNF418

9.30e-05197756int:SMARCAD1
InteractionZNF648 interactions

ZNF343 ZNF275 ZNF317 ZNF71

1.01e-0465754int:ZNF648
InteractionFBLN2 interactions

COL4A2 COL4A4 ZNF235 ZNF664

1.07e-0466754int:FBLN2
InteractionCIB3 interactions

ZBTB43 ZNF317 ZNF664 ZNF774

1.07e-0466754int:CIB3
InteractionLTBP4 interactions

MZF1 E4F1 ZNF169 ZNF574

1.14e-0467754int:LTBP4
InteractionZNF835 interactions

ZNF497 ZNF629 ZNF343 ZNF71

1.27e-0469754int:ZNF835
InteractionACTL7A interactions

ACTL7A APP

1.36e-045752int:ACTL7A
InteractionGOLGA6L9 interactions

ZNF497 ZNF48 ZNF587 ZNF629 ZNF417 ZNF574

1.54e-04216756int:GOLGA6L9
InteractionZNF774 interactions

ZNF48 ZNF587 ZNF417 ZNF774

2.15e-0479754int:ZNF774
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF135 ZNF211 ZNF497 ZNF585A ZNF473 MZF1 ZNF875 ZNF587 FIZ1 ZNF256 ZNF432 ZNF814 ZNF615 ZNF229 ZNF235 ZNF285 ZNF649 ZNF418 ZNF417 ZNF416 ZNF587B ZNF574 ZNF71 ZNF585B

5.13e-2011927524chr19q13
Cytoband19q13.43

ZNF497 ZNF587 ZNF256 ZNF814 ZNF418 ZNF417

7.05e-098775619q13.43
Cytoband19q13.4

ZNF135 ZNF211 MZF1 ZNF416 ZNF71

2.08e-077975519q13.4
Cytoband9q31

TMEFF1 ACTL7A FRRS1L

2.80e-06177539q31
Cytoband19q13.12

ZNF585A ZNF875 ZNF585B

2.30e-047275319q13.12
Cytoband19q13.41

ZNF432 ZNF615 ZNF649

2.92e-047875319q13.41
CytobandEnsembl 112 genes in cytogenetic band chr9q31

TMEFF1 ACTL7A FRRS1L

1.50e-03137753chr9q31
Cytoband1p36

ZNF436 ZBTB40

2.71e-03477521p36
Cytoband16p11.2

ZNF771 ZNF48 ZNF629

3.84e-0319175316p11.2
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF771 SP1 ZNF133 ZNF135 ZFP42 ZNF219 ZNF672 ZNF211 ZNF497 ZNF585A GTF3A ZNF48 ZNF157 ZNF473 ZNF556 ZNF337 MZF1 ZSCAN30 ZNF875 ZNF587 ZNF436 ZNF589 FIZ1 ZBTB43 ZNF256 ZNF629 ZBTB40 ZNF432 ZNF69 ZNF343 ZNF814 ZNF621 ZKSCAN2 ZNF214 ZNF721 E4F1 ZNF615 ZNF275 ZNF229 ZNF317 ZNF235 ZNF285 ZNF664 ZNF649 ZNF418 ZNF417 ZNF416 ZNF282 ZNF791 ZNF774 ZNF169 ZNF587B ZNF239 ZNF574 ZNF697 ZNF71 ZNF585B ZNF554

2.41e-73718665828
CoexpressionRAO_BOUND_BY_SALL4

TMEFF1 COL4A2 ZFP42 ZNF585A MAP1B MZF1 ZNF585B

6.97e-06247757MM1081
CoexpressionGSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP

SP1 ZNF672 ZNF473 ZBTB43 ZNF621 ZNF664

2.31e-05199756M6214
CoexpressionNIKOLSKY_BREAST_CANCER_19Q13.1_AMPLICON

ZNF585A ZNF875 ZNF585B

3.33e-0522753M8692
CoexpressionRAO_BOUND_BY_SALL4

TMEFF1 COL4A2 ZFP42 MAP1B MZF1 ZNF585B

4.71e-05226756M2521
CoexpressionMIKKELSEN_NPC_ICP_WITH_H3K4ME3

ZNF585A ZNF721 ZNF317 ZNF235 ZNF418 ZNF416 ZNF239 ZNF585B

8.76e-05497758MM863
CoexpressionURS_ADIPOCYTE_DIFFERENTIATION_DN

COL4A2 ZNF169 ZNF587B

9.55e-0531753M18395
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

ZNF211 ZSCAN30 KCP ZNF649 ZNF71

6.46e-06155755b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF771 ZNF135 ZNF585A MEGF6 ZNF629

6.67e-061567557ece590fd8f29382e349dd0e5e016d2926aeb518
ToppCellControl-B_naive-12|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZNF771 ZNF135 ZNF585A MEGF6 ZNF629

6.88e-061577554803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCellControl-B_naive-12|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZNF771 ZNF135 ZNF585A MEGF6 ZNF629

7.09e-0615875541318f864770370ce77ed3fa4a84f76c0c22c482
Drugvinylene

SP1 ZFP42 ZNF219 MZF1 ZNF589 ZNF235 ZNF418 ZNF71

1.45e-06245758CID000006326
Diseasemitogen-activated protein kinase 3 measurement

ZNF771 ZNF48

4.91e-055662EFO_0020579
DiseaseAlzheimer's disease 1 (implicated_via_orthology)

APLP2 APP

1.03e-047662DOID:0080348 (implicated_via_orthology)
Diseasenon-high density lipoprotein cholesterol measurement

COL4A2 SP1 FIZ1 APLP2 ZNF235 ZNF285 ZNF574

1.06e-03713667EFO_0005689
Diseasesystemic mastocytosis

ABCA2 MEGF6

1.43e-0325662MONDO_0016586
DiseaseBrain Diseases

LAMC3 APP

1.43e-0325662C0006111
DiseaseEncephalopathies

LAMC3 APP

1.67e-0327662C0085584
Diseaseantipsychotic drug use measurement

ZFP42 ZNF473

1.92e-0329662EFO_0007792
Diseaseconotruncal heart malformations

MAP1B ZNF343 LAMC3

2.15e-03114663MONDO_0016581
Diseaseapolipoprotein B measurement

COL4A2 SP1 ZNF229 ZNF235 ZNF285 ZNF664

3.65e-03663666EFO_0004615
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

ZNF629 KCP ZNF774

6.59e-03170663EFO_0000685, EFO_0007791, EFO_0007837
DiseaseAlzheimer's disease (implicated_via_orthology)

APLP2 APP

7.26e-0357662DOID:10652 (implicated_via_orthology)
Diseaseadverse effect, response to xenobiotic stimulus

ABCA2 STAB2

7.77e-0359662EFO_0009658, GO_0009410

Protein segments in the cluster

PeptideGeneStartEntry
VTEGKCAPFFYGGCG

APP

311

P05067
YKGFPGCDGKDGQKG

COL4A4

1311

P53420
KKFDVPCGGRDCSGG

COL4A2

36

P08572
EDGTRFFGKCGGYCG

ADAMTS20

1881

P59510
FFGKCGGYCGKCLPH

ADAMTS20

1886

P59510
SKGKCVRFIYGGCGG

APLP2

331

Q06481
KLSKPCCYIFPGGRG

MAP1B

256

P46821
LGFSGNCVGCGKKGF

GREB1

151

Q4ZG55
GKTKGCFRYGKPGCN

FRRS1L

101

Q9P0K9
CCGSPLFLKGTYGDG

ABCA2

1201

Q9BZC7
GSGRGKKIFGCSECE

FIZ1

406

Q96SL8
PFGEEFGICKDCPYG

ESM1

91

Q9NQ30
GEKPFKCYKCGRGFA

E4F1

571

Q66K89
GTNCEDGCPKGYYGK

MEGF6

591

O75095
AVYFKGERIGCGKGP

DROSHA

1301

Q9NRR4
CSGCAFGGKEYPSGA

KCP

601

Q6ZWJ8
CPYCKDSEGRGSGDP

SP1

606

P08047
LGTGYCKCGFAGLPR

ACTL7A

76

Q9Y615
GLRPYGCGVCGKKFK

ZBTB43

396

O43298
HTGEKPYVCGECGKG

ZNF615

506

Q8N8J6
PYVCGECGKGFPAKI

ZNF615

511

Q8N8J6
GEKPYVCGECGRGFS

ZNF343

461

Q6P1L6
GEKPYKCGVCGKGFG

ZNF48

136

Q96MX3
GEKPYKCGICGKGFG

ZNF48

216

Q96MX3
GERPYACGECGKPFS

ZNF497

466

Q6ZNH5
GEKPYECGECGKFFR

ZNF157

326

P51786
GDGPYKCRDCGKVFI

ZNF791

436

Q3KP31
TGDRPYKCYECGKGF

ZNF436

161

Q9C0F3
GEKPYACPDCGRAFG

ZNF771

171

Q7L3S4
GEKPYECGECGKAFS

ZNF135

406

P52742
GEKPYECGECGKAFS

ZSCAN30

381

Q86W11
GERPYECPECGKTFG

ZNF774

231

Q6NX45
GPYDCGECGKSYSRK

ZNF587

266

Q96SQ5
GERPYKCGECGKSFG

ZNF587

376

Q96SQ5
TGERPYRCGDCGKAF

ZNF574

546

Q6ZN55
TGARPYECGECGKSF

ZNF256

486

Q9Y2P7
GEKPYACGDCGRCFS

ZNF672

251

Q499Z4
GEKPYTCEERGKDFG

ZNF721

121

Q8TF20
TGEKPYECGQCGKGF

ZNF556

226

Q9HAH1
GPYDCGECGKSYSRK

ZNF417

266

Q8TAU3
GERPYKCGECGKSFG

ZNF417

376

Q8TAU3
TGDKPYKCGICGKGF

ZNF585B

741

Q52M93
TGERPYECGECGKSF

ZNF211

336

Q13398
CKGYFGRDCQACPGG

STAB2

1951

Q8WWQ8
TGDKPYKCGICGKGF

ZNF585A

741

Q6P3V2
PGEKPYSCGECGKGF

ZNF229

456

Q9UJW7
TGEKPYTCGVCGKGF

ZNF229

791

Q9UJW7
GEKPFRCTFEGCGKR

ZFP42

241

Q96MM3
PREKPFRCGECGKGF

ZNF697

256

Q5TEC3
SGEKPYVCRECGKGF

ZNF133

321

P52736
FHTGGKPYGCEECGK

ZNF587B

291

E7ETH6
AGKGPYECGECGKSF

ZNF587B

321

E7ETH6
HIGEGPYECKECGKG

ZNF621

201

Q6ZSS3
TGERPYECGECGKSF

ZNF416

321

Q9BWM5
GERPYECGKCGKSFT

ZNF416

546

Q9BWM5
GEKPYVCSECGRGFS

ZNF664

111

Q8N3J9
TGKRPYECGECGKSF

ZNF418

281

Q8TF45
TGERPYECGECGKSF

ZNF418

421

Q8TF45
GEKPYRCSECGKGFI

ZNF432

481

O94892
HTGEKPYGCNECGKG

ZNF432

591

O94892
GERPYECKICGKGFC

ZNF69

356

Q9UC07
TGEKPYRCGECGKCF

ZKSCAN2

826

Q63HK3
GERPFVCDYEGCGKA

GTF3A

66

Q92664
SGGKPYVCRECGRGF

ZNF875

296

P10072
GEKPYICRKCGRGFS

ZNF875

631

P10072
SCKYGGVCKEDGDGL

TMEFF1

81

Q8IYR6
HTGERPYKCGECGKG

ZNF239

341

Q16600
TGEKPYVCGECGRGF

ZNF589

271

Q86UQ0
GEKPYKCPECGKRFG

ZNF629

286

Q9UEG4
ERPYACGECGKAFRG

ZNF275

346

Q9NSD4
TGEKPYACGDCGKAF

ZNF71

181

Q9NQZ8
TGEKPYRCGECGKTF

ZNF71

461

Q9NQZ8
GEKPYRCDSCGKGFS

ZNF235

371

Q14590
TGEKPYGCDLCGKAF

ZNF317

441

Q96PQ6
GERPYKCKACGKGFS

ZNF285

536

Q96NJ3
GGRGATGKDCPFCGK

ZNF219

491

Q9P2Y4
KPYLCPDCGRGFGQK

ZNF169

456

Q14929
GEKPYTCPECGKGFS

ZNF214

466

Q9UL59
GERPYTCGECGKSFR

ZNF282

626

Q9UDV7
GKRPYECGECGKSFS

ZNF814

376

B7Z6K7
GARPYECGECGKSFS

ZNF814

516

B7Z6K7
PRERSYGCGECGKSF

ZNF814

571

B7Z6K7
TGDKPYVCRDCGKGF

ZBTB40

916

Q9NUA8
GEKPFVCKECGRGYT

ZNF337

316

Q9Y3M9
TGEKPYRCGECGKAF

ZNF473

781

Q8WTR7
TGEKPYGCIDCGKAF

ZNF649

341

Q9BS31
GEKPYGCGECGKAFN

ZNF554

376

Q86TJ5
GTCVCRPGFEGYKCD

LAMC3

981

Q9Y6N6
GEKPYHCGECGLGFT

MZF1

621

P28698