Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

SLIT2 THBS4 FBN1 COMP LAMA5 SSPOP FBN3

5.48e-07188527GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

SLIT2 THBS4 FBN1 COMP CELSR2 GAS6 LRP2 FBN3 NOTCH3 NOTCH4 STAB1

2.85e-067495211GO:0005509
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 SORL1 STAB1

9.11e-0616523GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 SORL1 STAB1

2.14e-0521523GO:0030228
GeneOntologyMolecularFunctionextracellular matrix binding

SLIT2 THBS4 ZAN ADAM9

3.90e-0573524GO:0050840
GeneOntologyMolecularFunctionintegrin binding

THBS4 FBN1 COMP ADAM9 LAMA5

9.09e-05175525GO:0005178
GeneOntologyMolecularFunctionlaminin binding

SLIT2 THBS4 ADAM9

9.42e-0534523GO:0043236
GeneOntologyMolecularFunctionlaminin-1 binding

SLIT2 THBS4

1.84e-048522GO:0043237
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNB1 PLXNB3

4.32e-0412522GO:0017154
GeneOntologyMolecularFunctiontumor necrosis factor receptor activity

TNFRSF14 TNFRSF10C

4.32e-0412522GO:0005031
GeneOntologyMolecularFunctionglycosaminoglycan binding

SLIT2 THBS4 FBN1 COMP STAB1

6.51e-04268525GO:0005539
GeneOntologyMolecularFunctioncell adhesion molecule binding

THBS4 FBN1 COMP ADAM9 LAMA5 PLXNB3 NOTCH3

8.75e-04599527GO:0050839
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

SORL1 STAB1

9.91e-0418522GO:0030169
GeneOntologyMolecularFunctioncollagen binding

THBS4 COMP ADAM9

1.23e-0381523GO:0005518
GeneOntologyMolecularFunctiondeath receptor activity

TNFRSF14 TNFRSF10C

1.35e-0321522GO:0005035
GeneOntologyMolecularFunctioncargo receptor activity

LRP2 SORL1 STAB1

1.42e-0385523GO:0038024
GeneOntologyMolecularFunctionheparin binding

SLIT2 THBS4 FBN1 COMP

1.56e-03192524GO:0008201
GeneOntologyMolecularFunctionreceptor tyrosine kinase binding

ZPR1 GAS6 FRS3

1.67e-0390523GO:0030971
GeneOntologyMolecularFunctionstructural molecule activity

SLIT2 THBS4 FBN1 COMP LAMA5 BSN SSPOP FBN3

2.00e-03891528GO:0005198
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

SLIT2 COMP

2.58e-0329522GO:0043395
GeneOntologyMolecularFunctionlipoprotein particle binding

SORL1 STAB1

3.75e-0335522GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

SORL1 STAB1

3.75e-0335522GO:0071814
GeneOntologyMolecularFunctionmolecular function inhibitor activity

SLIT2 CST9LP1 FNIP1 BSN SSPOP SORL1

4.38e-03596526GO:0140678
GeneOntologyMolecularFunctionfibronectin binding

THBS4 COMP

4.40e-0338522GO:0001968
GeneOntologyMolecularFunctionpeptidase regulator activity

CST9LP1 TNFRSF10C SSPOP SORL1

4.47e-03257524GO:0061134
GeneOntologyMolecularFunctionenzyme inhibitor activity

SLIT2 CST9LP1 BSN SSPOP SORL1

5.38e-03435525GO:0004857
GeneOntologyMolecularFunctionSH3 domain binding

SGIP1 ADAM9 LRP2

6.15e-03143523GO:0017124
GeneOntologyBiologicalProcesspositive regulation of intracellular protein transport

ZDHHC2 ZPR1 GAS6 ICE1 SORL1

1.19e-05116535GO:0090316
GeneOntologyBiologicalProcesspositive regulation of protein transport

ZDHHC2 ADAM9 ZPR1 GAS6 LRP2 ICE1 SORL1

1.66e-05319537GO:0051222
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

SLIT2 ERBB4 FBN1 COMP ADAM9 ZPR1 GAS6 FRS3 LRP2 SORL1

5.22e-058505310GO:0071363
GeneOntologyBiologicalProcesspositive regulation of intracellular transport

ZDHHC2 ZPR1 GAS6 ICE1 SORL1

5.95e-05162535GO:0032388
GeneOntologyBiologicalProcessresponse to growth factor

SLIT2 ERBB4 FBN1 COMP ADAM9 ZPR1 GAS6 FRS3 LRP2 SORL1

7.18e-058835310GO:0070848
GeneOntologyBiologicalProcesspositive regulation of establishment of protein localization

ZDHHC2 ADAM9 ZPR1 GAS6 LRP2 ICE1 SORL1

7.33e-05403537GO:1904951
GeneOntologyBiologicalProcessregulation of protein localization

ZDHHC2 ERBB4 FBN1 CELSR2 ADAM9 ZPR1 GAS6 LRP2 ICE1 NOTCH4 SORL1

8.19e-0510875311GO:0032880
GeneOntologyBiologicalProcessregulation of protein transport

ZDHHC2 FBN1 ADAM9 ZPR1 GAS6 LRP2 ICE1 SORL1

8.49e-05560538GO:0051223
GeneOntologyBiologicalProcessartery morphogenesis

COMP LRP2 NOTCH3 NOTCH4

9.18e-0592534GO:0048844
GeneOntologyBiologicalProcessregulation of intracellular protein transport

ZDHHC2 ZPR1 GAS6 ICE1 SORL1

1.03e-04182535GO:0033157
GeneOntologyBiologicalProcesspositive regulation of protein localization

ZDHHC2 ERBB4 ADAM9 ZPR1 GAS6 LRP2 ICE1 SORL1

1.23e-04591538GO:1903829
GeneOntologyBiologicalProcessnegative regulation of lamellipodium assembly

SLIT2 PLXNB3

1.35e-047532GO:0010593
GeneOntologyBiologicalProcessneuron projection morphogenesis

SLIT2 THBS4 CELSR2 LRP2 LAMA5 CPNE5 PLXNB1 PLXNB3 NOTCH3

1.85e-04802539GO:0048812
GeneOntologyBiologicalProcesscell morphogenesis

SLIT2 THBS4 CELSR2 LRP2 LAMA5 CPNE5 ZMYM4 PLXNB1 PLXNB3 NOTCH3 NOTCH4

1.88e-0411945311GO:0000902
GeneOntologyBiologicalProcessregulation of cell migration

SLIT2 ERBB4 THBS4 ADAM9 TNFRSF14 GAS6 LAMA5 BDKRB1 PLXNB1 PLXNB3 SORL1

2.13e-0412115311GO:0030334
GeneOntologyBiologicalProcessregulation of cellular localization

ZDHHC2 ERBB4 FBN1 CELSR2 ADAM9 ZPR1 GAS6 LRP2 ICE1 NOTCH4 SORL1

2.14e-0412125311GO:0060341
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SLIT2 THBS4 CELSR2 LRP2 LAMA5 CPNE5 PLXNB1 PLXNB3 NOTCH3

2.16e-04819539GO:0120039
GeneOntologyBiologicalProcesspositive regulation of endocytic recycling

ZDHHC2 SORL1

2.31e-049532GO:2001137
GeneOntologyBiologicalProcesscell projection morphogenesis

SLIT2 THBS4 CELSR2 LRP2 LAMA5 CPNE5 PLXNB1 PLXNB3 NOTCH3

2.31e-04826539GO:0048858
GeneOntologyBiologicalProcessnegative regulation of lamellipodium organization

SLIT2 PLXNB3

2.88e-0410532GO:1902744
GeneOntologyBiologicalProcessregulation of establishment of protein localization

ZDHHC2 FBN1 ADAM9 ZPR1 GAS6 LRP2 ICE1 SORL1

3.01e-04674538GO:0070201
GeneOntologyBiologicalProcessregulation of cell motility

SLIT2 ERBB4 THBS4 ADAM9 TNFRSF14 GAS6 LAMA5 BDKRB1 PLXNB1 PLXNB3 SORL1

3.43e-0412805311GO:2000145
GeneOntologyBiologicalProcesscell-cell adhesion

ZDHHC2 SLIT2 THBS4 ZAN COMP CELSR2 ADAM9 TNFRSF14 PLXNB3 NOTCH4

3.62e-0410775310GO:0098609
GeneOntologyBiologicalProcesskidney development

SLIT2 ERBB4 FBN1 LRP2 LAMA5 NOTCH3

3.71e-04372536GO:0001822
GeneOntologyBiologicalProcesspositive regulation of transport

ZDHHC2 ERBB4 SGIP1 ADAM9 ZPR1 GAS6 LRP2 ICE1 BDKRB1 SORL1

3.73e-0410815310GO:0051050
GeneOntologyBiologicalProcessartery development

COMP LRP2 NOTCH3 NOTCH4

3.79e-04133534GO:0060840
GeneOntologyBiologicalProcessrenal system development

SLIT2 ERBB4 FBN1 LRP2 LAMA5 NOTCH3

4.51e-04386536GO:0072001
GeneOntologyBiologicalProcessregulation of locomotion

SLIT2 ERBB4 THBS4 ADAM9 TNFRSF14 GAS6 LAMA5 BDKRB1 PLXNB1 PLXNB3 SORL1

4.66e-0413275311GO:0040012
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

ERBB4 THBS4 FBN1 ADAM9 TNFRSF14 GAS6 SLCO3A1 FNIP1

4.86e-04724538GO:0001934
GeneOntologyBiologicalProcessregulation of protein phosphorylation

SLIT2 ERBB4 THBS4 FBN1 ADAM9 TNFRSF14 GAS6 SLCO3A1 FNIP1 BDKRB1

5.40e-0411335310GO:0001932
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

ZDHHC2 SLIT2 SGIP1 ADAM9 GAS6 ELAPOR1 LRP2 FNIP1 ICE1 PLXNB1 PLXNB3

5.95e-0413665311GO:0051130
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

SLIT2 FBN1 LRP2 SORL1

5.97e-04150534GO:0090288
GeneOntologyBiologicalProcessregulation of leukocyte migration

SLIT2 THBS4 TNFRSF14 GAS6 BDKRB1

6.05e-04267535GO:0002685
GeneOntologyBiologicalProcessprotein localization to cell periphery

ZDHHC2 ERBB4 GAS6 LAMA5 PREPL SORL1

7.21e-04422536GO:1990778
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

ERBB4 THBS4 FBN1 ADAM9 TNFRSF14 GAS6 SLCO3A1 FNIP1

7.92e-04780538GO:0042327
GeneOntologyCellularComponentextracellular matrix

SLIT2 LAMB4 THBS4 FBN1 ZAN COMP LAMA5 SSPOP FBN3

3.07e-05656529GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SLIT2 LAMB4 THBS4 FBN1 ZAN COMP LAMA5 SSPOP FBN3

3.15e-05658529GO:0030312
GeneOntologyCellularComponentcell surface

SLIT2 ADAM9 TNFRSF14 LRP2 CORIN TNFRSF10C BSN PLXNB3 NOTCH3 NOTCH4 SORL1

7.35e-0511115211GO:0009986
GeneOntologyCellularComponentbasement membrane

LAMB4 THBS4 FBN1 LAMA5

2.41e-04122524GO:0005604
GeneOntologyCellularComponentcollagen-containing extracellular matrix

SLIT2 LAMB4 THBS4 FBN1 COMP LAMA5 SSPOP

3.22e-04530527GO:0062023
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNB1 PLXNB3

4.65e-0413522GO:0002116
GeneOntologyCellularComponentmicrofibril

FBN1 FBN3

4.65e-0413522GO:0001527
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ZDHHC2 ABCA4 SGIP1 ELAPOR1 LRP2 FMN2 ALDH3B1 BSN SORL1 STAB1

1.25e-0313075210GO:0030659
GeneOntologyCellularComponentvesicle membrane

ZDHHC2 ABCA4 SGIP1 ELAPOR1 LRP2 FMN2 ALDH3B1 BSN SORL1 STAB1

1.39e-0313255210GO:0012506
GeneOntologyCellularComponentinhibitory synapse

ERBB4 BSN

2.69e-0331522GO:0060077
GeneOntologyCellularComponentneuromuscular junction

ERBB4 THBS4 LAMA5

2.73e-03112523GO:0031594
DomainEGF_2

SLIT2 LAMB4 THBS4 FBN1 ZAN COMP CELSR2 ADAM9 GAS6 LRP2 LAMA5 C7 SSPOP FBN3 NOTCH3 NOTCH4 SORL1 STAB1

2.37e-212654918PS01186
DomainEGF_1

SLIT2 LAMB4 THBS4 FBN1 ZAN COMP CELSR2 ADAM9 GAS6 LRP2 LAMA5 C7 SSPOP FBN3 NOTCH3 NOTCH4 STAB1

5.13e-202554917PS00022
DomainEGF-like_CS

SLIT2 LAMB4 THBS4 FBN1 ZAN COMP CELSR2 ADAM9 GAS6 LRP2 LAMA5 C7 FBN3 NOTCH3 NOTCH4 SORL1 STAB1

7.63e-202614917IPR013032
DomainEGF_3

SLIT2 THBS4 FBN1 ZAN COMP CELSR2 ADAM9 GAS6 LRP2 C7 SSPOP FBN3 NOTCH3 NOTCH4 SORL1 STAB1

5.47e-192354916PS50026
DomainEGF-like_dom

SLIT2 THBS4 FBN1 ZAN COMP CELSR2 ADAM9 GAS6 LRP2 LAMA5 C7 FBN3 NOTCH3 NOTCH4 SORL1 STAB1

1.39e-182494916IPR000742
DomainEGF

SLIT2 THBS4 FBN1 ZAN COMP CELSR2 ADAM9 GAS6 LRP2 LAMA5 FBN3 NOTCH3 NOTCH4 SORL1 STAB1

2.16e-172354915SM00181
DomainGrowth_fac_rcpt_

ERBB4 THBS4 FBN1 COMP CELSR2 GAS6 ELAPOR1 LRP2 LAMA5 FBN3 NOTCH3 NOTCH4 STAB1

1.17e-161564913IPR009030
DomainEGF_CA

SLIT2 THBS4 FBN1 COMP CELSR2 GAS6 LRP2 FBN3 NOTCH3 NOTCH4 STAB1

1.38e-141224911SM00179
DomainEGF-like_Ca-bd_dom

SLIT2 THBS4 FBN1 COMP CELSR2 GAS6 LRP2 FBN3 NOTCH3 NOTCH4 STAB1

1.66e-141244911IPR001881
DomainEGF

SLIT2 THBS4 ZAN CELSR2 GAS6 LRP2 FBN3 NOTCH3 NOTCH4 STAB1

8.94e-131264910PF00008
DomainEGF_Ca-bd_CS

SLIT2 THBS4 FBN1 COMP GAS6 LRP2 FBN3 NOTCH3 NOTCH4

3.26e-1297499IPR018097
DomainEGF_CA

SLIT2 THBS4 FBN1 COMP GAS6 LRP2 FBN3 NOTCH3 NOTCH4

3.93e-1299499PS01187
DomainEGF_CA

THBS4 FBN1 COMP GAS6 LRP2 FBN3 NOTCH3 NOTCH4

5.60e-1186498PF07645
DomainhEGF

SLIT2 CELSR2 GAS6 FBN3 NOTCH3 NOTCH4

8.56e-1128496PF12661
DomainASX_HYDROXYL

SLIT2 FBN1 CELSR2 GAS6 LRP2 FBN3 NOTCH3 NOTCH4

1.91e-10100498PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SLIT2 FBN1 CELSR2 GAS6 LRP2 FBN3 NOTCH3 NOTCH4

3.06e-10106498IPR000152
DomainLDLR_class-A_CS

LRP2 CORIN C7 SSPOP SORL1

6.19e-0840495IPR023415
DomainLdl_recept_a

LRP2 CORIN C7 SSPOP SORL1

1.14e-0745495PF00057
Domain-

LRP2 CORIN C7 SSPOP SORL1

1.27e-07464954.10.400.10
DomainLDLRA_1

LRP2 CORIN C7 SSPOP SORL1

1.59e-0748495PS01209
Domain-

SLIT2 THBS4 COMP CELSR2 GAS6 LAMA5

1.73e-07954962.60.120.200
DomainLDLRA_2

LRP2 CORIN C7 SSPOP SORL1

1.76e-0749495PS50068
DomainLDrepeatLR_classA_rpt

LRP2 CORIN C7 SSPOP SORL1

1.76e-0749495IPR002172
DomainLDLa

LRP2 CORIN C7 SSPOP SORL1

1.76e-0749495SM00192
DomainLaminin_G

SLIT2 THBS4 CELSR2 GAS6 LAMA5

4.16e-0758495IPR001791
DomaincEGF

FBN1 GAS6 LRP2 FBN3

5.99e-0726494IPR026823
DomaincEGF

FBN1 GAS6 LRP2 FBN3

5.99e-0726494PF12662
DomainEGF_LAM_2

LAMB4 CELSR2 LAMA5 STAB1

1.09e-0630494PS50027
DomainEGF_LAM_1

LAMB4 CELSR2 LAMA5 STAB1

1.09e-0630494PS01248
DomainConA-like_dom

SLIT2 THBS4 ZAN COMP CELSR2 GAS6 LAMA5

1.57e-06219497IPR013320
DomainTNFR/NGFR_Cys_rich_reg

CELSR2 TNFRSF14 LAMA5 TNFRSF10C

1.62e-0633494IPR001368
DomainLaminin_EGF

LAMB4 CELSR2 LAMA5 STAB1

2.06e-0635494PF00053
DomainEGF_Lam

LAMB4 CELSR2 LAMA5 STAB1

2.06e-0635494SM00180
DomainLAM_G_DOMAIN

SLIT2 CELSR2 GAS6 LAMA5

2.89e-0638494PS50025
DomainLaminin_EGF

LAMB4 CELSR2 LAMA5 STAB1

2.89e-0638494IPR002049
DomainLaminin_G_2

SLIT2 CELSR2 GAS6 LAMA5

3.56e-0640494PF02210
DomainLamG

SLIT2 CELSR2 GAS6 LAMA5

5.25e-0644494SM00282
DomainTIL_dom

ZAN LRP2 SSPOP

6.05e-0614493IPR002919
DomainEGF_extracell

ADAM9 LRP2 NOTCH3 STAB1

1.83e-0560494IPR013111
DomainEGF_2

ADAM9 LRP2 NOTCH3 STAB1

1.83e-0560494PF07974
DomainThbs/COMP_coiled-coil

THBS4 COMP

2.02e-053492IPR024665
DomainCOMP

THBS4 COMP

2.02e-053492PF11598
DomainFBN

FBN1 FBN3

2.02e-053492IPR011398
DomainNotch

NOTCH3 NOTCH4

4.03e-054492IPR008297
DomainNODP

NOTCH3 NOTCH4

4.03e-054492PF07684
DomainNotch_NODP_dom

NOTCH3 NOTCH4

4.03e-054492IPR011656
DomainNotch_NOD_dom

NOTCH3 NOTCH4

4.03e-054492IPR010660
DomainNOD

NOTCH3 NOTCH4

4.03e-054492PF06816
DomainNOD

NOTCH3 NOTCH4

4.03e-054492SM01338
DomainNODP

NOTCH3 NOTCH4

4.03e-054492SM01339
DomainTNFR

CELSR2 TNFRSF14 TNFRSF10C

4.23e-0526493SM00208
DomainTSP_3

THBS4 COMP

6.71e-055492PF02412
DomainLNR

NOTCH3 NOTCH4

6.71e-055492PS50258
DomainTSP3

THBS4 COMP

6.71e-055492PS51234
DomainTSP_CTER

THBS4 COMP

6.71e-055492PS51236
Domain-

THBS4 COMP

6.71e-0554924.10.1080.10
DomainThrombospondin_C

THBS4 COMP

6.71e-055492IPR008859
DomainTSP_C

THBS4 COMP

6.71e-055492PF05735
DomainThrombospondin_3_rpt

THBS4 COMP

6.71e-055492IPR017897
DomainThrombospondin_3-like_rpt

THBS4 COMP

6.71e-055492IPR003367
DomainTSP_type-3_rpt

THBS4 COMP

6.71e-055492IPR028974
DomainTB

FBN1 FBN3

1.40e-047492PF00683
DomainNotch_dom

NOTCH3 NOTCH4

1.40e-047492IPR000800
DomainNotch

NOTCH3 NOTCH4

1.40e-047492PF00066
DomainNL

NOTCH3 NOTCH4

1.40e-047492SM00004
Domain-

FBN1 FBN3

1.87e-0484923.90.290.10
DomainPlexin_cytopl

PLXNB1 PLXNB3

2.40e-049492PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNB1 PLXNB3

2.40e-049492IPR013548
DomainPlexin

PLXNB1 PLXNB3

2.40e-049492IPR031148
DomainTB

FBN1 FBN3

2.40e-049492PS51364
DomainTB_dom

FBN1 FBN3

2.40e-049492IPR017878
DomainLaminin_G_1

SLIT2 GAS6

3.65e-0411492PF00054
DomainTIL

ZAN SSPOP

4.38e-0412492PF01826
DomainC8

ZAN SSPOP

4.38e-0412492PF08742
DomainUnchr_dom_Cys-rich

ZAN SSPOP

5.16e-0413492IPR014853
DomainC8

ZAN SSPOP

5.16e-0413492SM00832
DomainLdl_recept_b

LRP2 SORL1

6.01e-0414492PF00058
DomainLDLRB

LRP2 SORL1

6.01e-0414492PS51120
DomainLY

LRP2 SORL1

6.93e-0415492SM00135
DomainLDLR_classB_rpt

LRP2 SORL1

6.93e-0415492IPR000033
DomainVWD

ZAN SSPOP

7.90e-0416492SM00216
DomainVWF_type-D

ZAN SSPOP

7.90e-0416492IPR001846
DomainLaminin_N

LAMB4 LAMA5

7.90e-0416492IPR008211
DomainLAMININ_NTER

LAMB4 LAMA5

7.90e-0416492PS51117
DomainVWFD

ZAN SSPOP

7.90e-0416492PS51233
DomainLaminin_N

LAMB4 LAMA5

7.90e-0416492PF00055
DomainVWD

ZAN SSPOP

7.90e-0416492PF00094
DomainLamNT

LAMB4 LAMA5

7.90e-0416492SM00136
DomainCTCK_1

SLIT2 SSPOP

1.00e-0318492PS01185
DomainVWC_out

ZAN SSPOP

1.12e-0319492SM00215
DomainTNFR_c6

TNFRSF14 TNFRSF10C

1.51e-0322492PF00020
DomainCys_knot_C

SLIT2 SSPOP

1.95e-0325492IPR006207
DomainCTCK_2

SLIT2 SSPOP

1.95e-0325492PS01225
DomainIPT

PLXNB1 PLXNB3

2.27e-0327492SM00429
DomainTNFR_NGFR_1

TNFRSF14 TNFRSF10C

2.62e-0329492PS00652
DomainTNFR_NGFR_2

TNFRSF14 TNFRSF10C

2.62e-0329492PS50050
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

FMN2 NOTCH3 NOTCH4

4.77e-0524423M11190
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH3 NOTCH4

8.62e-055422M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH3 NOTCH4

8.62e-055422MM14733
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB4 THBS4 COMP LAMA5

1.10e-0484424M7098
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH3 NOTCH4

1.29e-046422M27068
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH3 NOTCH4

1.80e-047422MM14734
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH3 NOTCH4

4.69e-0411422M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH3 NOTCH4

5.61e-0412422M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH3 NOTCH4

5.61e-0412422M47533
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH3 NOTCH4

6.62e-0413422M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH3 NOTCH4

6.62e-0413422M47534
PathwayPID_NOTCH_PATHWAY

SSPOP NOTCH3 NOTCH4

7.12e-0459423M17
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

FBN1 ADAM9 LAMA5 FBN3

7.78e-04140424M587
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP NOTCH3 NOTCH4

1.08e-0368423M27303
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

THBS4 FBN1 COMP NOTCH3 STAB1

1.23e-093154531550482
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

BSN PREPL ZMYM4 PLXNB1

1.33e-06525449455477
Pubmed

Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.

NOTCH3 NOTCH4

2.37e-06254233665264
Pubmed

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.

FBN1 NOTCH3

2.37e-06254232616814
Pubmed

Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.

NOTCH3 NOTCH4

2.37e-06254217696940
Pubmed

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.

FBN1 FBN3

2.37e-06254215221638
Pubmed

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.

NOTCH3 NOTCH4

2.37e-06254225658374
Pubmed

A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.

NOTCH3 NOTCH4

2.37e-06254211777956
Pubmed

COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.

THBS4 COMP

2.37e-06254230464261
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

ERBB4 BSN PLXNB1 STAB1

2.71e-066254419367581
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

THBS4 COMP ADAM9 GAS6 LRP2 LAMA5 C7 CPNE5 FIGNL1 TSPAN1

5.10e-061070541023533145
Pubmed

Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.

COMP NOTCH3

7.09e-06354230502484
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH3 NOTCH4

7.09e-06354225846406
Pubmed

Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.

THBS4 COMP

7.09e-06354233910854
Pubmed

Prognostic role of TSPAN1, KIAA1324 and ESRP1 in prostate cancer.

ELAPOR1 TSPAN1

7.09e-06354233455017
Pubmed

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype.

NOTCH3 NOTCH4

7.09e-06354215645445
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 LAMA5 NOTCH3

8.97e-062654334189436
Pubmed

Genetic link between renal birth defects and congenital heart disease.

SLIT2 LRP2 LAMA5

1.13e-052854327002738
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH3 NOTCH4

1.42e-05454228061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH3 NOTCH4

1.42e-05454224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH3 NOTCH4

1.42e-05454220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH3 NOTCH4

1.42e-05454219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH3 NOTCH4

1.42e-05454228669409
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN3

1.42e-05454225034023
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH3 NOTCH4

1.42e-05454211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH3 NOTCH4

1.42e-05454224151014
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH3 NOTCH4

1.42e-05454211401408
Pubmed

Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.

PLXNB1 PLXNB3

1.42e-05454215147296
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH3 NOTCH4

1.42e-05454210194420
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH3 NOTCH4

1.42e-0545428898100
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH3 NOTCH4

1.42e-05454211459941
Pubmed

MicroRNA-183 suppresses cancer stem-like cell properties in EBV-associated nasopharyngeal carcinoma.

NOTCH3 NOTCH4

1.42e-05454227431799
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH3 NOTCH4

1.42e-05454218184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH3 NOTCH4

1.42e-05454215917835
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH3 NOTCH4

1.42e-05454223444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH3 NOTCH4

1.42e-05454217920003
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

ERBB4 L3MBTL1 SORL1

1.54e-053154327798109
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LAMB4 THBS4 LRP2 FMN2 ICE1 SSPOP FBN3 PLXNB3

1.71e-0573654829676528
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

LAMA5 ICE1 BSN PREPL ZMYM4 PLXNB1 STAB1

1.73e-0552954714621295
Pubmed

Genomic analysis of mouse retinal development.

ZDHHC2 SLIT2 RP1L1 GAS6 ALDH3B1 BSN ZMYM4 TSPAN1 STAB1

2.26e-05100654915226823
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

NOTCH3 NOTCH4

2.36e-05554221726900
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS4 COMP

2.36e-05554230622267
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH3 NOTCH4

2.36e-05554221124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH3 NOTCH4

2.36e-05554223675950
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

NOTCH3 NOTCH4

2.36e-05554221602525
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH3 NOTCH4

2.36e-05554211101851
Pubmed

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.

PLXNB1 PLXNB3

2.36e-05554212183458
Pubmed

Plexin-B3 is a functional receptor for semaphorin 5A.

PLXNB1 PLXNB3

2.36e-05554215218527
Pubmed

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

THBS4 COMP

2.36e-05554218467703
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH3 NOTCH4

2.36e-05554215882997
Pubmed

Interplay between scatter factor receptors and B plexins controls invasive growth.

PLXNB1 PLXNB3

2.36e-05554215184888
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 SORL1

2.36e-05554219047013
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH3 NOTCH4

2.36e-05554220554499
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

SLIT2 FBN1 L3MBTL1 FRS3 LAMA5 NOTCH3 STAB1

2.49e-0556054721653829
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH3 NOTCH4

3.54e-0565429111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH3 NOTCH4

3.54e-05654220870902
Pubmed

A study on Notch signaling in human breast cancer.

NOTCH3 NOTCH4

3.54e-05654217822320
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH3 NOTCH4

3.54e-05654212244553
Pubmed

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.

CELSR2 ZPR1

3.54e-05654222003152
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH3 NOTCH4

3.54e-05654219503073
Pubmed

Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.

NOTCH3 NOTCH4

3.54e-0565427835890
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH3 NOTCH4

3.54e-05654218299578
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH3 NOTCH4

3.54e-05654215019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH3 NOTCH4

3.54e-05654222615412
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH3 NOTCH4

3.54e-05654221991352
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

SLIT2 FBN1 COMP ADAM9 GAS6

4.21e-0524854524006456
Pubmed

Human ligands of the Notch receptor.

NOTCH3 NOTCH4

4.94e-05754210079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH3 NOTCH4

4.94e-05754212846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH3 NOTCH4

4.94e-05754211518718
Pubmed

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium.

NOTCH3 NOTCH4

4.94e-05754211344305
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNB1 PLXNB3

6.59e-05854215661641
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH3 NOTCH4

6.59e-05854222156581
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS4 COMP

6.59e-05854224460873
Pubmed

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.

SLIT2 COMP

6.59e-05854216774856
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH3 NOTCH4

6.59e-05854212242716
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH3 NOTCH4

6.59e-0585429858718
Pubmed

Proteomic analysis of in vivo phosphorylated synaptic proteins.

SGIP1 FMN2 BSN

7.84e-055354315572359
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH3 NOTCH4

8.46e-05954211118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH3 NOTCH4

8.46e-05954216245338
Pubmed

Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.

CELSR2 ZPR1

8.46e-05954220442857
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH3 NOTCH4

8.46e-05954212370315
Pubmed

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

CELSR2 ZPR1

8.46e-05954218179892
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH3 NOTCH4

1.06e-041054223665443
Pubmed

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.

NOTCH3 NOTCH4

1.06e-041054214766969
Pubmed

Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.

SLIT2 NOTCH4

1.06e-041054217496152
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH3 NOTCH4

1.06e-041054233915108
Pubmed

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

SLIT2 NOTCH3 NOTCH4

1.08e-045954321421844
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH3 NOTCH4

1.29e-041154216607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH3 NOTCH4

1.29e-041154215499562
Pubmed

A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.

ERBB4 FBN1

1.29e-041154217903305
Pubmed

Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.

ERBB4 PLXNB1

1.29e-041154225315821
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH3 NOTCH4

1.29e-041154210878608
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH3 NOTCH4

1.29e-04115429187150
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH3 NOTCH4

1.29e-041154212866128
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FBN1 ADAM9 LRP2 FMN2 CPNE5 PREPL ZMYM4 PLXNB3 STAB1

1.48e-04128554935914814
Pubmed

Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.

L3MBTL1 SSPOP PLXNB3

1.51e-046654315790807
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH3 NOTCH4

1.55e-041254210952889
Pubmed

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.

PLXNB1 PLXNB3

1.55e-041254212123608
Pubmed

A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system.

PLXNB1 PLXNB3

1.55e-041254220478304
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH3 NOTCH4

1.55e-041254215465494
InteractionNTN5 interactions

FBN1 LRP2 NOTCH3 SORL1

4.36e-0724534int:NTN5
InteractionIGFL3 interactions

ADAM9 LRP2 LAMA5 NOTCH3 SORL1

1.56e-0675535int:IGFL3
InteractionSIRPD interactions

CELSR2 ADAM9 GAS6 LAMA5 SORL1

3.07e-0686535int:SIRPD
InteractionODAPH interactions

FBN1 LAMA5 IPO4 PREPL

8.27e-0649534int:ODAPH
InteractionFBXO2 interactions

SLIT2 FBN1 ADAM9 GAS6 LRP2 LAMA5 NOTCH3 SORL1

1.11e-05411538int:FBXO2
InteractionZFP41 interactions

FBN1 LRP2 NOTCH3 SORL1

1.52e-0557534int:ZFP41
InteractionZNF224 interactions

LRP2 NOTCH3 SORL1

1.90e-0520533int:ZNF224
InteractionZNF408 interactions

FBN1 LRP2 CDC27 NOTCH3 SORL1

3.91e-05145535int:ZNF408
InteractionADAM32 interactions

ADAM9 GAS6 NOTCH3

4.28e-0526533int:ADAM32
InteractionRNF123 interactions

LAMB4 THBS4 LRP2 FMN2 AKIRIN2 ICE1 ALDH3B1 SSPOP FBN3 PLXNB3

4.88e-058245310int:RNF123
InteractionPRG2 interactions

CELSR2 ADAM9 GAS6 LAMA5 NOTCH3 SORL1

9.97e-05285536int:PRG2
InteractionDLK2 interactions

ADAM9 LRP2 NOTCH3

1.15e-0436533int:DLK2
InteractionST14 interactions

SLIT2 FBN1 ADAM9 GAS6 NOTCH3

2.09e-04207535int:ST14
InteractionLGALS1 interactions

CELSR2 LRP2 LAMA5 TNFRSF10C NOTCH3 SORL1

2.29e-04332536int:LGALS1
InteractionLY86 interactions

CELSR2 ADAM9 GAS6 LAMA5 FIGNL1

2.61e-04217535int:LY86
InteractionCD160 interactions

CELSR2 ADAM9 TNFRSF14

2.73e-0448533int:CD160
InteractionMFAP5 interactions

FBN1 LAMA5 NOTCH3

3.47e-0452533int:MFAP5
InteractionCBLN4 interactions

CELSR2 ADAM9 LAMA5 SORL1

3.47e-04127534int:CBLN4
InteractionALG14 interactions

TNFRSF10C TSPAN1

3.68e-0411532int:ALG14
CytobandEnsembl 112 genes in cytogenetic band chr6p21

C6orf89 FRS3 CPNE5 NOTCH4

2.92e-03503544chr6p21
Cytoband6p21.1

FRS3 CPNE5

4.05e-03805426p21.1
CytobandEnsembl 112 genes in cytogenetic band chr3p21

BSN PLXNB1 STAB1

6.18e-03316543chr3p21
Cytoband3p21.31

BSN PLXNB1

6.24e-031005423p21.31
GeneFamilyPlexins

PLXNB1 PLXNB3

1.30e-049352683
GeneFamilyLaminin subunits

LAMB4 LAMA5

2.37e-0412352626
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

ZPR1 BSN

3.76e-041535226
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF14 TNFRSF10C

1.43e-0329352782
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT2 LAMB4 THBS4 FBN1 COMP GAS6 LAMA5 SSPOP FBN3

2.42e-10196549M3008
CoexpressionNABA_CORE_MATRISOME

SLIT2 LAMB4 THBS4 FBN1 COMP GAS6 LAMA5 SSPOP FBN3

4.76e-09275549M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT2 THBS4 FBN1 COMP GAS6 LAMA5 SSPOP

1.30e-07191547MM17059
CoexpressionNABA_MATRISOME

SLIT2 LAMB4 THBS4 FBN1 COMP ADAM9 GAS6 LAMA5 SSPOP FBN3 PLXNB1 PLXNB3

9.11e-0710265412M5889
CoexpressionNABA_CORE_MATRISOME

SLIT2 THBS4 FBN1 COMP GAS6 LAMA5 SSPOP

1.33e-06270547MM17057
CoexpressionNABA_MATRISOME

SLIT2 THBS4 FBN1 COMP ADAM9 CST9LP1 GAS6 LAMA5 SSPOP PLXNB1 PLXNB3

5.41e-0610085411MM17056
CoexpressionLIU_CDX2_TARGETS_UP

NOTCH3 NOTCH4 TSPAN1

5.16e-0535543M16637
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

SLIT2 ERBB4 FBN1 CELSR2 ELAPOR1 LRP2 LAMA5 SLCO3A1 CORIN FIGNL1 PLXNB1

1.98e-067835111gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

ERBB4 THBS4 FBN1 ADAM9 LRP2 LAMA5 CORIN C2CD2 NOTCH3 SORL1

4.90e-059055110gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_1000_k-means-cluster#4

ABCA4 SGIP1 TNFRSF14 TNFRSF10C PLXNB3 NOTCH4 STAB1

6.93e-05428517JC_hmvEC_1000_K4
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

ERBB4 THBS4 FBN1 LRP2 LAMA5 CORIN NOTCH3

1.03e-04456517gudmap_kidney_P0_JuxtaGlom_Ren1_500
ToppCellBiopsy_IPF-Mesenchymal-Myofibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

SLIT2 FBN1 SGIP1 COMP CORIN C7

1.38e-07200536c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

LAMB4 THBS4 FBN1 SGIP1 COMP

3.18e-06191535aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR2 ELAPOR1 LAMA5 PLXNB1 TSPAN1

3.35e-06193535ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR1 LRP2 LAMA5 PLXNB1 TSPAN1

3.43e-061945353701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR1 LRP2 LAMA5 PLXNB1 TSPAN1

3.43e-0619453565f9bf126be26114c2c3f4c46d48318986212a92
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLIT2 FBN1 SGIP1 SLCO3A1 C7

3.43e-0619453560622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT2 FBN1 COMP C7 NOTCH3

3.52e-061955352b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT2 FBN1 COMP C7 NOTCH3

3.52e-06195535c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCellIPF-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

SLIT2 FBN1 SGIP1 COMP C7

3.61e-061965357fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

SLIT2 FBN1 SGIP1 COMP C7

3.61e-061965352d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCellmetastatic_Lymph_Node-Fibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

THBS4 FBN1 SGIP1 COMP C7

3.61e-06196535275e153347caf94edc0c50021bbab49c8696fecb
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLIT2 FBN1 SLCO3A1 C7 BSN

3.70e-06197535fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLIT2 FBN1 COMP C7 BDKRB1

3.79e-06198535bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT2 FBN1 SGIP1 C7 NOTCH3

3.89e-061995354d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT2 FBN1 SGIP1 C7 NOTCH3

3.89e-0619953593e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCelldistal-2-mesenchymal-Adventitial_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLIT2 FBN1 COMP C7 BDKRB1

3.89e-0619953597b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLIT2 FBN1 ADAM9 SLCO3A1 C7

3.98e-062005359b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellcellseq-Mesenchymal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLIT2 FBN1 SGIP1 C7 NOTCH3

3.98e-06200535238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

ERBB4 LRP2 C7 TSPAN1 SORL1

3.98e-062005351f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

SLIT2 FBN1 SGIP1 C7 NOTCH3

3.98e-06200535d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell(02)_Cycling_Basal_(regeneration)-(3)_72hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

FBN1 GAS6 ELAPOR1 TSPAN1

1.91e-0513353432c6a00671af309c4b0b90e93549733729684c61
ToppCellClub_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

RP1L1 ELAPOR1 BDKRB1 NOTCH3

2.21e-05138534133015953fc660d00339f47b415da5e9872313a2
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP2 C7 NOTCH4 TSPAN1

2.61e-051445341b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

FBN1 SGIP1 C7 NOTCH3

3.22e-051525343a1414ba6a4972698c3262a00b124428835c35cb
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

FBN1 SGIP1 C7 NOTCH3

3.22e-05152534ee7855d76a49d07a032677a4dc83aa6116d50518
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERBB4 ELAPOR1 LAMA5 PLXNB1

3.66e-051575346ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

SLIT2 FBN1 SGIP1 C7

3.84e-051595343f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ELAPOR1 BDKRB1 NOTCH3 TSPAN1

4.03e-05161534bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 C7 BDKRB1 NOTCH3

4.65e-05167534e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 FBN1 COMP C7

4.76e-051685344b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 FBN1 COMP C7

4.87e-0516953447fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 FBN1 COMP C7

4.87e-05169534e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 CELSR2 CORIN NOTCH3

5.10e-05171534b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 CELSR2 CORIN NOTCH3

5.10e-051715349d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 FBN1 COMP C7

5.10e-051715345d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 C7 BDKRB1 NOTCH3

5.58e-0517553459249c9e83952d7277010e7be3c779e26399eb5d
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 COMP BSN STAB1

5.58e-051755349d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 COMP BSN STAB1

5.58e-05175534f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 C7 BDKRB1 NOTCH3

5.58e-05175534b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 FBN1 SSPOP FIGNL1

5.71e-051765343766e0533b103ec92ac75eba3df02e287efc53fa
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

SLIT2 FBN1 GAS6 NOTCH3

5.71e-05176534ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SGIP1 COMP CORIN

5.71e-051765349bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZDHHC2 THBS4 GAS6 LRP2

5.71e-051765348e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZDHHC2 THBS4 GAS6 LRP2

5.71e-05176534ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SGIP1 COMP CORIN

5.71e-051765343f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 FBN1 SSPOP FIGNL1

5.71e-05176534aa1bada2175d8370fc71939a607407155259d195
ToppCellClub_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

ELAPOR1 LAMA5 NOTCH3 TSPAN1

5.71e-0517653488c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GAS6 ELAPOR1 LRP2 TSPAN1

5.71e-05176534ac76f2cd6c63f30b38b89b58bad2baa4dde8ce3a
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SGIP1 SSPOP PLXNB1 NOTCH3

5.71e-05176534e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SGIP1 SSPOP PLXNB1 NOTCH3

5.71e-05176534f931192e3cc65414e2245354f443473696cc7ce8
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 CORIN CPNE5 C2CD2

5.83e-0517753430f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

FBN1 COMP MEIKIN CORIN

5.96e-05178534edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 CELSR2 PLXNB1 PLXNB3

6.23e-05180534da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 CELSR2 PLXNB1 PLXNB3

6.23e-051805345b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 CELSR2 PLXNB1 PLXNB3

6.23e-0518053450758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGIP1 CELSR2 FRS3 PLXNB3

6.36e-051815343aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGIP1 CELSR2 FRS3 PLXNB3

6.36e-05181534997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

ZAN GAS6 NOTCH4 TSPAN1

6.36e-051815343d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

FBN1 SGIP1 COMP CORIN

6.36e-05181534bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT2 FBN1 SGIP1 C7

6.36e-051815349ede19228ba5c0668a9c06c915510b95585216ef
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGIP1 CELSR2 FRS3 PLXNB3

6.36e-05181534e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR2 FRS3 FIGNL1 NOTCH3

6.50e-0518253439f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 THBS4 FBN1 C7

6.50e-051825343dfa9187e9d2bab1d199079d29209c4648220ada
ToppCelldroplet-Lung-nan-21m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR1 LRP2 PLXNB1 TSPAN1

6.50e-0518253440539ade8c3cd12b61f1cd0d493828e58282796b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLIT2 SGIP1 SLCO3A1 NOTCH3

6.64e-051835348a799807fbf24456a9811e0c64068187940a2f71
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ZAN GAS6 NOTCH4 TSPAN1

6.64e-051835342c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ZAN LRP2 SSPOP

6.78e-051845342cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLIT2 SGIP1 GAS6 NOTCH3

6.78e-05184534689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 ERBB4 COMP SLCO3A1

6.78e-051845348fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ZAN LRP2 SSPOP

6.78e-05184534ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ZAN LRP2 SSPOP

6.78e-051845342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLIT2 SGIP1 GAS6 NOTCH3

6.78e-05184534102b6f621a5b551e622f97b12d787c080b052a72
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 SLCO3A1 C2CD2 NOTCH3

6.92e-0518553451dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 CPNE5 FIGNL1 PLXNB3

6.92e-05185534554c5d812197fbf66bf279fcc953277e926ade15
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 SLCO3A1 C2CD2 NOTCH3

6.92e-05185534a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, Lineage and Cell Type

ZAN GAS6 NOTCH4 TSPAN1

6.92e-051855347564a47df4a4e3af30d40aa0f48bd9d9c82358ae
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELAPOR1 LAMA5 PLXNB1 TSPAN1

7.07e-0518653437b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SLIT2 FBN1 SGIP1 NOTCH3

7.07e-05186534cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 FBN1 SGIP1 C7

7.07e-051865345473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBS4 GAS6 LRP2 LAMA5

7.07e-051865341587667e5084ac43505d027af925ba711e228150
ToppCellfacs-Lung-EPCAM-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 LRP2 TSPAN1 SORL1

7.07e-051865347c4eb769574f9f32753cea1cc38c711dabba88b9
ToppCellEpithelial-C_(AT2)|World / shred on cell class and cell subclass (v4)

GAS6 ELAPOR1 LRP2 TSPAN1

7.07e-05186534b7b1763fc52b4485d843a4a6727055e6c95ebad3
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM9 SLCO3A1 C7 NOTCH3

7.22e-05187534d591a3c216997663ab77710fed0d230ffc37e41a
ToppCelldroplet-Fat-SCAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR2 ELAPOR1 PLXNB1 TSPAN1

7.22e-051875345fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCelldroplet-Fat-SCAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR2 ELAPOR1 PLXNB1 TSPAN1

7.22e-05187534766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM9 SLCO3A1 C7 NOTCH3

7.22e-05187534d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

SLIT2 FBN1 SGIP1 C7

7.22e-0518753492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM9 SLCO3A1 C7 NOTCH3

7.22e-05187534ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 LRP2 PLXNB1 PLXNB3

7.22e-0518753497e520705491c8f52a32025311a9fa7b9176979a
ToppCelldroplet-Fat-SCAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR2 ELAPOR1 PLXNB1 TSPAN1

7.22e-05187534f49d06600060deeb2fc1b1da5b93496535f20104
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ADAM9 GAS6 FRS3 TSPAN1

7.22e-05187534d3563bb087e476baea5b59389e4d34d0ff98cac5
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR1 LAMA5 PLXNB1 TSPAN1

7.22e-05187534fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

SLIT2 FBN1 SGIP1 C7

7.22e-05187534bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELAPOR1 LAMA5 PLXNB1 TSPAN1

7.37e-051885348ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

SLIT2 THBS4 C7 NOTCH4

7.37e-05188534c90669b51e1902fe7726555290c91c92a911df83
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELAPOR1 LAMA5 PLXNB1 TSPAN1

7.37e-05188534137ed9958044fab7a13648affb469585d1c48cf6
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLIT2 FBN1 SLCO3A1 C7

7.52e-05189534e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 ERBB4 COMP SLCO3A1

7.52e-05189534e059be2965cca70ff5576df055d0af1775b76e00
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR2 ELAPOR1 PLXNB1 TSPAN1

7.52e-05189534ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR2 ELAPOR1 PLXNB1 TSPAN1

7.52e-05189534dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ComputationalMetal / Ca ion binding.

SLIT2 THBS4 FBN1 COMP ADAM9 GAS6

3.87e-06133356MODULE_324
ComputationalDRG (dorsal root ganglia) genes.

SLIT2 FBN1 TNFRSF14 LAMA5 C7 NOTCH3 STAB1

1.99e-04384357MODULE_2
ComputationalLung genes.

SLIT2 TNFRSF14 LAMA5 C7 NOTCH3 TSPAN1 STAB1

4.20e-04434357MODULE_5
ComputationalECM and collagens.

SLIT2 FBN1 ADAM9 GAS6 NOTCH3

7.48e-04225355MODULE_47
ComputationalAdhesion molecules.

THBS4 FBN1 COMP LAMA5

1.08e-03141354MODULE_122
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN3

9.85e-063542DOID:65 (implicated_via_orthology)
Diseaselarge artery stroke, coronary artery disease

CELSR2 C6orf89 ZPR1

1.30e-0525543EFO_0001645, EFO_0005524
Diseasefamilial hyperlipidemia

CELSR2 ZPR1 GAS6 ELAPOR1

4.33e-05106544MONDO_0001336
Diseasecarbonic anhydrase-related protein 10 measurement

CELSR2 C7

9.14e-058542EFO_0020233
Diseasephospholipids in very small VLDL measurement

CELSR2 ZPR1 GAS6

1.13e-0451543EFO_0022300
Diseasephospholipids in medium VLDL measurement

CELSR2 ZPR1 GAS6

1.20e-0452543EFO_0022154
Diseasetotal lipids in medium VLDL

CELSR2 ZPR1 GAS6

1.35e-0454543EFO_0022153
Diseasecystic kidney disease (implicated_via_orthology)

SLIT2 LAMA5

1.47e-0410542DOID:2975 (implicated_via_orthology)
Diseasetriglycerides in LDL measurement

CELSR2 ZPR1 GAS6

1.50e-0456543EFO_0022320
Diseasesphingomyelin measurement

COMP CELSR2 C6orf89 ZPR1 FBN3

1.55e-04278545EFO_0010118
Diseasetriglycerides in IDL measurement

CELSR2 ZPR1 GAS6

1.66e-0458543EFO_0022149
Diseasephospholipids in VLDL measurement

CELSR2 ZPR1 GAS6

1.75e-0459543EFO_0022301
DiseaseMalignant neoplasm of skin

ERBB4 NOTCH3 NOTCH4

1.75e-0459543C0007114
DiseaseSkin Neoplasms

ERBB4 NOTCH3 NOTCH4

1.75e-0459543C0037286
Diseasephospholipids in small VLDL measurement

CELSR2 ZPR1 GAS6

1.84e-0460543EFO_0022146
Diseasetotal lipids in VLDL measurement

CELSR2 ZPR1 GAS6

1.84e-0460543EFO_0022314
Diseasefree cholesterol in VLDL measurement

CELSR2 ZPR1 GAS6

1.93e-0461543EFO_0022276
Diseasetriglycerides in medium LDL measurement

CELSR2 ZPR1 GAS6

2.03e-0462543EFO_0022322
Diseasetriglycerides in small LDL measurement

CELSR2 ZPR1 GAS6

2.34e-0465543EFO_0022323
Diseasecholesterol in large VLDL measurement

CELSR2 ZPR1 GAS6

2.34e-0465543EFO_0021902
Diseasetotal lipids in small VLDL

CELSR2 ZPR1 GAS6

2.55e-0467543EFO_0022148
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

LRP2 C7

2.95e-0414542DOID:10976 (biomarker_via_orthology)
DiseaseImpaired cognition

NOTCH3 SORL1

2.95e-0414542C0338656
Diseasehematocrit

ZAN C6orf89 GAS6 LRP2 BSN CDC27 NOTCH4 STAB1

4.75e-041011548EFO_0004348
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

CELSR2 ZPR1

4.94e-0418542EFO_0008317, EFO_0008589
Diseasesodium-coupled monocarboxylate transporter 1 measurement

CELSR2 ZPR1

5.51e-0419542EFO_0802076
Diseaselipid measurement, lipoprotein measurement

CELSR2 ZPR1 GAS6

6.08e-0490543EFO_0004529, EFO_0004732
Diseaseobesity (implicated_via_orthology)

PLXNB1 PLXNB3 NOTCH3 NOTCH4

6.52e-04215544DOID:9970 (implicated_via_orthology)
Diseasestroke, coronary artery disease

CELSR2 C6orf89

6.75e-0421542EFO_0000712, EFO_0001645
DiseaseMalignant neoplasm of breast

ERBB4 ABCA4 ELAPOR1 CDC27 PLXNB1 NOTCH3 NOTCH4 SORL1

7.06e-041074548C0006142
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

CELSR2 ZPR1 GAS6 CDC27

7.72e-04225544EFO_0008317, EFO_0010351
Diseasemean arterial pressure, alcohol drinking

C6orf89 RP1L1 ICE1

7.79e-0498543EFO_0004329, EFO_0006340
DiseaseEpilepsy, Benign Psychomotor, Childhood

SLIT2 BDKRB1

8.11e-0423542C0393672
DiseaseEpilepsy, Lateral Temporal

SLIT2 BDKRB1

8.11e-0423542C0393682
DiseaseUncinate Epilepsy

SLIT2 BDKRB1

8.11e-0423542C0014558
DiseaseEpilepsy, Temporal Lobe

SLIT2 BDKRB1

8.11e-0423542C0014556
Diseasecystatin C measurement

ERBB4 CST9LP1 LRP2 FNIP1 BSN

8.37e-04402545EFO_0004617
DiseaseCarcinoma, Pancreatic Ductal

NOTCH3 NOTCH4

8.84e-0424542C0887833
Diseasesystemic scleroderma (is_implicated_in)

FBN1 NOTCH4

8.84e-0424542DOID:418 (is_implicated_in)
Diseaseceramide measurement

CELSR2 CORIN PREPL FBN3

9.08e-04235544EFO_0010222
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

CELSR2 ZPR1 GAS6

1.01e-03107543EFO_0004614, EFO_0004615
Diseaseremnant cholesterol measurement

CELSR2 ZPR1 GAS6

1.03e-03108543EFO_0010815
Diseasebrain cancer (implicated_via_orthology)

L3MBTL1 NOTCH3

1.04e-0326542DOID:1319 (implicated_via_orthology)
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

CELSR2 ZPR1 GAS6

1.12e-03111543EFO_0004530, EFO_0008595
Diseasefatty acid measurement

ABCA4 CELSR2 ZPR1 GAS6 NOTCH4

1.20e-03436545EFO_0005110
Diseaselow density lipoprotein cholesterol measurement, lipid measurement

CELSR2 ZPR1 GAS6

1.21e-03114543EFO_0004529, EFO_0004611
Diseasetotal cholesterol measurement, low density lipoprotein cholesterol measurement

CELSR2 ZPR1 GAS6

1.21e-03114543EFO_0004574, EFO_0004611
Diseaseantihyperlipidemic drug use measurement

CELSR2 ZPR1 GAS6

1.24e-03115543EFO_0803367
DiseaseCone-Rod Dystrophy 2

ABCA4 ADAM9

1.29e-0329542C3489532
Diseasearteriosclerosis (is_marker_for)

TNFRSF14 NOTCH4

1.29e-0329542DOID:2349 (is_marker_for)
Diseasecolorectal cancer, overall survival

ERBB4 SORL1

1.29e-0329542EFO_0000638, MONDO_0005575
Diseaseomega-3 polyunsaturated fatty acid measurement

CELSR2 ZPR1 GAS6

1.33e-03118543EFO_0010119
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

CELSR2 ZPR1 GAS6

1.40e-03120543EFO_0004611, EFO_0004639
Diseasecholesterol to total lipids in very large HDL percentage

CELSR2 ZPR1

1.48e-0331542EFO_0022243
Diseasecholesteryl esters to total lipids in large LDL percentage

CELSR2 ZPR1

1.48e-0331542EFO_0022249
Diseaseintestinal cancer (implicated_via_orthology)

ERBB4 NOTCH3

1.57e-0332542DOID:10155 (implicated_via_orthology)
Diseasecoffee consumption

LAMB4 C6orf89

1.57e-0332542EFO_0004330
Diseaseuridine measurement

SLIT2 ABCA4

1.57e-0332542EFO_0010546
Diseasecholesteryl ester measurement, low density lipoprotein cholesterol measurement

CELSR2 ZPR1 GAS6

1.61e-03126543EFO_0004611, EFO_0010351
Diseasesystolic blood pressure, alcohol drinking

FBN1 C6orf89 RP1L1

1.68e-03128543EFO_0004329, EFO_0006335
Diseasebullous pemphigoid

FMN2 CPNE5

1.78e-0334542EFO_0007187
Diseasevisual epilepsy (implicated_via_orthology)

ERBB4 C7

1.78e-0334542DOID:11832 (implicated_via_orthology)
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

TNFRSF10C PCYT1B STAB1

1.80e-03131543C4704862
Diseasepolyunsaturated fatty acid measurement

CELSR2 ZPR1 GAS6

1.80e-03131543EFO_0010733
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

TNFRSF10C PCYT1B STAB1

1.80e-03131543C4552091
DiseaseJuvenile arthritis

TNFRSF10C PCYT1B STAB1

1.80e-03131543C3495559
DiseaseJuvenile psoriatic arthritis

TNFRSF10C PCYT1B STAB1

1.80e-03131543C3714758

Protein segments in the cluster

PeptideGeneStartEntry
NFNDSGACVTQCPQT

ERBB4

251

Q15303
SQLFPQNATACDNAP

BDKRB1

16

P46663
QGIFCNVNNPCFQSP

ABCA4

71

P78363
SFQQTDPCCTSDAQP

AKIRIN2

101

Q53H80
PCYVDDNCDPQTVAN

ALDH3B1

216

P43353
ACDNCPQKSNPDQAD

COMP

406

P49747
NVEQGCSLPDPCDSN

CELSR2

1786

Q9HCU4
QACFDNDECSAQPGP

FBN3

2481

Q75N90
FLSNQSCFPAACENP

FIGNL1

241

Q6PIW4
PCNPGFFKTNNSTCQ

ELAPOR1

381

Q6UXG2
TPSQPNFNTCTQCHN

BSN

181

Q9UPA5
LTAPAPFADETNCQC

PCYT1B

41

Q9Y5K3
PFADETNCQCQAPHE

PCYT1B

46

Q9Y5K3
PSCSSQQFEEPCHVN

PLXNB1

1316

O43157
QFPDCASCLQAQDPL

PLXNB3

476

Q9ULL4
PNQDPPEDDSTCQCQ

L3MBTL1

156

Q9Y468
DNCPFQESPELNNTC

CST9LP1

106

Q5W188
CLQSPENDHCFPDAQ

NOTCH3

1591

Q9UM47
NSSNEFPANASEICC

MEIKIN

321

A0A087WXM9
TETCQPSQFNCPNHR

LRP2

1146

P98164
TSPQTLCNAHQNCPD

LRP2

3566

P98164
TCANCTAQSQPVAFP

LAMA5

956

O15230
QEAPCGNNLSCPQED

ICE1

1481

Q9Y2F5
NLQCAASTAQESCPP

C2CD2

241

Q9Y426
CQPCPAQNSAEYQAL

FBN1

696

P35555
NNNEAPSECPAQPKC

FRS3

271

O43559
VPQDSCKTCFPQQDQ

FNIP1

891

Q8TF40
NSGFATCVQNLPDQC

GAS6

106

Q14393
QPCVGNAFETQSCEP

C7

61

P10643
CNGSSQFCQPDVFIQ

ADAM9

486

Q13443
DCSQFPEENSDNQTC

CORIN

556

Q9Y5Q5
PCQPCACNNNIDVTD

LAMB4

966

A4D0S4
QNESEPIPANCTGCA

C6orf89

146

Q6UWU4
DCFREPCNQNAQTNA

FMN2

576

Q9NZ56
FSNCLPNSCTTQVPN

CDC27

176

P30260
ACQSCPSEPNTAALQ

IPO4

731

Q8TEX9
HEFPLNGNQENPSCC

CPNE5

396

Q9HCH3
EANCENPTEAPNCSR

SORL1

1356

Q92673
QNCPGPEHQSQACFT

SSPOP

1731

A2VEC9
DPYSPCNNNCECQTD

SLCO3A1

466

Q9UIG8
EDQCSFDQPQPEEQC

CCDC59

136

Q9P031
TCQFPDPCQNAQLCQ

NOTCH4

61

Q99466
TNSSFQDQAPTCCQE

C10orf120

36

Q5SQS8
ACDSCPDVSNPNQSD

THBS4

601

P35443
EVLQFSTNCPECNAP

ZPR1

251

O75312
SPGDLENQQQCCFPT

RP1L1

1246

Q8IWN7
PNPQLLCCDNTQNDA

SGIP1

626

Q9BQI5
TNASNNEPSCFPCTV

TNFRSF10C

76

O14798
QDPNRFGPDCQSVCS

STAB1

151

Q9NY15
DTNSDPKNCPFQLCS

PREPL

396

Q4J6C6
RTSPCDNFDCQNGAQ

SLIT2

1121

O94813
ESQDTLCQNCPPGTF

TNFRSF14

156

Q92956
CSFPTCLVNQDPEQA

ZDHHC2

291

Q9UIJ5
MFCNQQSVCDPPSQN

ZMYM4

846

Q5VZL5
ENSAFPPFCCNDNVT

TSPAN1

166

O60635
PPFCCNDNVTNTANE

TSPAN1

171

O60635
NHTQGCFPESPCLQN

ZAN

2701

Q9Y493
CFPESPCLQNPCQND

ZAN

2706

Q9Y493