Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-24	3.03e-07	37	31	4	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-7 ERVK-21 ERVK-9 ERVK-24	3.38e-07	38	31	4	GO:0070001
GeneOntologyMolecularFunction	annealing activity	FXR1 FMR1 ANXA1	1.22e-06	14	31	3	GO:0140666
GeneOntologyMolecularFunction	RNA strand annealing activity	FXR1 FMR1	2.33e-05	5	31	2	GO:0033592
GeneOntologyMolecularFunction	single-stranded RNA binding	FXR1 ILF3 FMR1 ANXA1	2.53e-05	111	31	4	GO:0003727
GeneOntologyMolecularFunction	zinc ion binding	NR1H3 ERVK-7 ERVK-21 ERVK-9 ERVK-24 ZMYM4 UBR4	3.53e-04	891	31	7	GO:0008270
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-7 FMR1	4.81e-04	21	31	2	GO:0035613
GeneOntologyMolecularFunction	mRNA 3'-UTR AU-rich region binding	FXR1 ILF3	9.23e-04	29	31	2	GO:0035925
GeneOntologyMolecularFunction	molecular condensate scaffold activity	FXR1 FMR1	1.93e-03	42	31	2	GO:0140693
GeneOntologyMolecularFunction	transition metal ion binding	NR1H3 ERVK-7 ERVK-21 ERVK-9 ERVK-24 ZMYM4 UBR4	1.94e-03	1189	31	7	GO:0046914
GeneOntologyBiologicalProcess	regulation of translation at presynapse, modulating synaptic transmission	FXR1 FMR1	6.55e-06	3	31	2	GO:0099577
GeneOntologyBiologicalProcess	regulation of translation at presynapse	FXR1 FMR1	6.55e-06	3	31	2	GO:0140244
GeneOntologyBiologicalProcess	viral process	ERVK-7 ERVK-21 ERVK-9 ILF3 FMR1 ERVK-24	5.73e-05	464	31	6	GO:0016032
GeneOntologyBiologicalProcess	regulation of translation at synapse, modulating synaptic transmission	FXR1 FMR1	7.82e-05	9	31	2	GO:0099547
GeneOntologyBiologicalProcess	positive regulation of long-term neuronal synaptic plasticity	FXR1 FMR1	1.19e-04	11	31	2	GO:0048170
GeneOntologyBiologicalProcess	establishment of RNA localization	FXR1 ERVK-21 FMR1 ATR	1.41e-04	178	31	4	GO:0051236
GeneOntologyBiologicalProcess	positive regulation of miRNA-mediated gene silencing	FXR1 FMR1	1.43e-04	12	31	2	GO:2000637
GeneOntologyBiologicalProcess	positive regulation of post-transcriptional gene silencing by RNA	FXR1 FMR1	1.69e-04	13	31	2	GO:1900370
GeneOntologyBiologicalProcess	positive regulation of post-transcriptional gene silencing	FXR1 FMR1	1.69e-04	13	31	2	GO:0060148
GeneOntologyBiologicalProcess	regulation of translation at synapse	FXR1 FMR1	1.69e-04	13	31	2	GO:0140243
GeneOntologyBiologicalProcess	regulation of fatty acid biosynthetic process	NR1H3 ANXA1 UBR4	1.78e-04	73	31	3	GO:0042304
GeneOntologyBiologicalProcess	RNA localization	FXR1 ERVK-21 FMR1 ATR	3.00e-04	217	31	4	GO:0006403
GeneOntologyCellularComponent	dendritic spine head	FMR1 SYNE1	2.20e-04	16	29	2	GO:0044327
Domain	FXMRP1_C_core	FXR1 FMR1	6.03e-06	3	27	2	IPR022034
Domain	Agenet	FXR1 FMR1	6.03e-06	3	27	2	PF05641
Domain	FXMRP1_C_core	FXR1 FMR1	6.03e-06	3	27	2	PF12235
Domain	Agenet-like_dom	FXR1 FMR1	6.03e-06	3	27	2	IPR008395
Domain	AGENET_LIKE	FXR1 FMR1	6.03e-06	3	27	2	PS51641
Domain	KH_1	FXR1 FMR1	1.37e-03	38	27	2	PF00013
Domain	-	FXR1 FMR1	1.44e-03	39	27	2	3.30.1370.10
Domain	KH	FXR1 FMR1	1.52e-03	40	27	2	SM00322
Domain	KH_dom	FXR1 FMR1	1.52e-03	40	27	2	IPR004087
Domain	KH_TYPE_1	FXR1 FMR1	1.67e-03	42	27	2	PS50084
Domain	KH_dom_type_1	FXR1 FMR1	1.83e-03	44	27	2	IPR004088
Domain	DH_1	OBSCN ARHGEF10L	3.72e-03	63	27	2	PS00741
Domain	RhoGEF	OBSCN ARHGEF10L	4.32e-03	68	27	2	SM00325
Domain	DH_2	OBSCN ARHGEF10L	4.57e-03	70	27	2	PS50010
Domain	RhoGEF	OBSCN ARHGEF10L	4.57e-03	70	27	2	PF00621
Domain	DH-domain	OBSCN ARHGEF10L	4.70e-03	71	27	2	IPR000219
Domain	-	OBSCN ARHGEF10L	4.70e-03	71	27	2	1.20.900.10
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-24	5.18e-07	18	31	3	18664271
Pubmed	The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses.	FXR1 FMR1	7.69e-07	2	31	2	12581522
Pubmed	The RNA-binding protein fragile X-related 1 regulates somite formation in Xenopus laevis.	FXR1 FMR1	7.69e-07	2	31	2	16000371
Pubmed	Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs.	FXR1 FMR1	7.69e-07	2	31	2	17057366
Pubmed	FXR1, an autosomal homolog of the fragile X mental retardation gene.	FXR1 FMR1	7.69e-07	2	31	2	7781595
Pubmed	Highly conserved 3' UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1.	FXR1 FMR1	7.69e-07	2	31	2	8634689
Pubmed	ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice.	FMR1 ATR	7.69e-07	2	31	2	18160412
Pubmed	Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P.	FXR1 FMR1	7.69e-07	2	31	2	10527928
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-7 ERVK-21 ERVK-9 ERVK-24	1.49e-06	94	31	4	21542922
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FXR1 ILF3 MDN1 FMR1 SYNE1	1.95e-06	234	31	5	36243803
Pubmed	LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation.	FXR1 FMR1	2.31e-06	3	31	2	38587486
Pubmed	Transport kinetics of FMRP containing the I304N mutation of severe fragile X syndrome in neurites of living rat PC12 cells.	FXR1 FMR1	2.31e-06	3	31	2	15380484
Pubmed	The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.	FXR1 FMR1	2.31e-06	3	31	2	10888599
Pubmed	Fragile X-related proteins regulate mammalian circadian behavioral rhythms.	FXR1 FMR1	2.31e-06	3	31	2	18589395
Pubmed	Spatial control of nucleoporin condensation by fragile X-related proteins.	FXR1 FMR1	2.31e-06	3	31	2	32706158
Pubmed	Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression.	FXR1 FMR1	2.31e-06	3	31	2	12417522
Pubmed	The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2.	FXR1 FMR1	2.31e-06	3	31	2	7489725
Pubmed	Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them.	FXR1 FMR1	2.31e-06	3	31	2	8668200
Pubmed	Evidence that fragile X mental retardation protein is a negative regulator of translation.	FXR1 FMR1	2.31e-06	3	31	2	11157796
Pubmed	Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses.	FXR1 FMR1	2.31e-06	3	31	2	27770568
Pubmed	Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer.	FXR1 FMR1	2.31e-06	3	31	2	32878499
Pubmed	Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes.	FXR1 FMR1	2.31e-06	3	31	2	26612855
Pubmed	Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis.	FXR1 FMR1	2.31e-06	3	31	2	9259278
Pubmed	Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.	FXR1 FMR1	2.31e-06	3	31	2	19487368
Pubmed	ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice.	FMR1 ATR	2.31e-06	3	31	2	19710035
Pubmed	FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin-proteasome system.	FXR1 FMR1	2.31e-06	3	31	2	36732356
Pubmed	Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.	FXR1 FMR1	2.31e-06	3	31	2	20442204
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	FXR1 ILF3 FMR1 SYNE1 ARHGEF10L	3.14e-06	258	31	5	37794589
Pubmed	Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex.	FXR1 FMR1	4.61e-06	4	31	2	10567518
Pubmed	The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons.	FXR1 FMR1	4.61e-06	4	31	2	16571602
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-7 ERVK-24	4.61e-06	4	31	2	10469592
Pubmed	Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP.	FXR1 FMR1	4.61e-06	4	31	2	18664458
Pubmed	A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.	FXR1 FMR1	4.61e-06	4	31	2	10556305
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-7 ERVK-21	7.68e-06	5	31	2	12629516
Pubmed	Novel FMRP interaction networks linked to cellular stress.	FXR1 FMR1	7.68e-06	5	31	2	32525608
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	FXR1 ILF3 FMR1 ANXA1	8.82e-06	147	31	4	28977470
Pubmed	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.	FXR1 FMR1	1.15e-05	6	31	2	11438699
Pubmed	A protein interaction landscape of breast cancer.	FXR1 ILF3 MDN1 FMR1 ANXA1 UBR4	1.79e-05	634	31	6	34591612
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FXR1 ILF3 MDN1 FMR1 SYNE1 KIAA1217 UBR4	1.80e-05	963	31	7	28671696
Pubmed	Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.	FXR1 ILF3 FMR1	1.82e-05	57	31	3	17932509
Pubmed	Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.	FXR1 FMR1	2.15e-05	8	31	2	25225333
Pubmed	Phagocytosis imprints heterogeneity in tissue-resident macrophages.	NR1H3 ANXA1	2.15e-05	8	31	2	28432199
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	FXR1 ILF3 MDN1 FMR1 SYNE1 KIAA1217 DHRS7 UBR4	3.74e-05	1496	31	8	32877691
Pubmed	CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1.	FXR1 FMR1	4.21e-05	11	31	2	35989368
Pubmed	Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma.	FXR1 FMR1	4.21e-05	11	31	2	29142209
Pubmed	Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.	FXR1 FMR1	4.21e-05	11	31	2	22022532
Pubmed	FXR1P but not FMRP regulates the levels of mammalian brain-specific microRNA-9 and microRNA-124.	FXR1 FMR1	4.21e-05	11	31	2	21957233
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ARNT FXR1 ILF3 ANXA1 ZMYM4	4.28e-05	444	31	5	34795231
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-21 ERVK-9	5.05e-05	12	31	2	14557543
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	FXR1 ILF3 FMR1 ANXA1 UBR4	5.90e-05	475	31	5	31040226
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ARNT FXR1 MDN1 FLYWCH1 ZMYM4 UBR4	9.56e-05	857	31	6	25609649
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	JCAD FXR1 ILF3 FMR1	1.00e-04	274	31	4	34244482
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OBSCN FLYWCH1 ARHGEF10L	1.01e-04	101	31	3	10997877
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	MDN1 ANXA1 ZMYM4	1.16e-04	106	31	3	19394292
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ARNT ILF3 MDN1 FMR1 ATR FLYWCH1 ZMYM4	1.17e-04	1294	31	7	30804502
Pubmed	Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression.	ARNT ATR	1.30e-04	19	31	2	36359803
Pubmed	The association of UBAP2L and G3BP1 mediated by small nucleolar RNA is essential for stress granule formation.	FXR1 FMR1	1.60e-04	21	31	2	37059803
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	FXR1 ILF3 FMR1 FLYWCH1 ANXA1 SYNE1	1.67e-04	949	31	6	36574265
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	FXR1 FMR1 SYNE1	1.68e-04	120	31	3	31413325
Pubmed	β-Actin mRNA interactome mapping by proximity biotinylation.	ILF3 FMR1	2.10e-04	24	31	2	31189591
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FXR1 ILF3 MDN1 FMR1 ATR SYNE1 UBR4	2.11e-04	1425	31	7	30948266
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	OBSCN FXR1 ILF3 SYNE1	2.12e-04	333	31	4	32665550
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	OBSCN FXR1 ILF3 FMR1	2.14e-04	334	31	4	30425250
Pubmed	Characterization of Staufen 1 ribonucleoprotein complexes.	ILF3 FMR1	2.28e-04	25	31	2	15303970
Pubmed	Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.	OBSCN SYNE1	2.28e-04	25	31	2	38877142
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FXR1 MDN1 FMR1 ANXA1 UBR4	2.61e-04	653	31	5	22586326
Pubmed	C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.	FXR1 FMR1	2.66e-04	27	31	2	29420262
Pubmed	The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.	NR1H3 ARNT	2.66e-04	27	31	2	26469385
Pubmed	Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.	FXR1 ILF3	3.29e-04	30	31	2	15782174
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	FAT1 MDN1 UBR4	4.66e-04	170	31	3	23314748
Pubmed	Defining the membrane proteome of NK cells.	FXR1 ILF3 MDN1 FMR1 DHRS7 UBR4	5.07e-04	1168	31	6	19946888
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	ILF3 MDN1 ATR FLYWCH1	6.76e-04	453	31	4	29656893
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ILF3 MDN1 ANXA1 SYNE1 UBR4	6.84e-04	807	31	5	30575818
Pubmed	Proteome analysis of the HIV-1 Gag interactome.	FXR1 ILF3	7.11e-04	44	31	2	25010285
Pubmed	Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.	FXR1 ILF3 FMR1	7.16e-04	197	31	3	32434143
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	FXR1 ILF3 FMR1 ATR	7.28e-04	462	31	4	31138677
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	FXR1 ILF3 FMR1 SYNE1	7.34e-04	463	31	4	34901782
Pubmed	Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.	FXR1 FMR1	7.77e-04	46	31	2	37207277
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	FXR1 ILF3 MDN1 FMR1 ZMYM4	8.50e-04	847	31	5	35850772
Cytoband	1p36.13	ARHGEF10L UBR4	6.64e-04	56	31	2	1p36.13
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN ARHGEF10L	1.93e-03	66	18	2	722
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	OBSCN MFAP3	1.10e-02	161	18	2	593
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR1H3 FAT1 ARHGEF10L GBGT1	4.51e-06	185	27	4	a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR1H3 FAT1 ARHGEF10L GBGT1	4.51e-06	185	27	4	5053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	OBSCN JCAD SYNE1 KIAA1217	4.81e-06	188	27	4	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN JCAD SYNE1 KIAA1217	5.01e-06	190	27	4	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN JCAD SYNE1 KIAA1217	5.44e-06	194	27	4	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OBSCN LPAR3 FAT1 KIAA1217	5.78e-06	197	27	4	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BTBD16 LPAR3 TDO2	3.99e-05	110	27	3	bede775886b45cce4aa229baead0e800b5be25a8
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocye.Tnr.Ctps_(Ctps)\|Striatum / BrainAtlas - Mouse McCarroll V32	BTBD16 LPAR3 TDO2	7.17e-05	134	27	3	bc550d3b44f1e1e1c18971c110e816bcffd79d14
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	BTBD16 LPAR3 TDO2	7.17e-05	134	27	3	90a34ae53a602a92f6f998e7cf061d8f4f0da527
ToppCell	facs-Marrow-T-cells-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1H3 ANXA1 SYNE1	9.06e-05	145	27	3	4f8b188a93a038afbc7a446df8467ad544f5b1cb
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANXA1 SYNE1 DHRS7	9.63e-05	148	27	3	74f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANXA1 SYNE1 DHRS7	9.82e-05	149	27	3	4de52569611e63a780cde9bd111d6d9c11a05a11
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANXA1 SYNE1 DHRS7	9.82e-05	149	27	3	c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCell	Myeloid-Myeloid-E_(Neutrophils)\|Myeloid / shred on cell class and cell subclass (v4)	ANXA1 SYNE1 DHRS7	1.00e-04	150	27	3	1bffb8d86b737ac43be902d9468041aef3542f1f
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.02e-04	151	27	3	ced4f7ee377a23a804ae6fde624e8b55b79f1fd8
ToppCell	Immune_cells-Neutrophils\|World / Lineage and Cell class	ANXA1 SYNE1 DHRS7	1.02e-04	151	27	3	056301bedb4285e797250b55d79ee1790a17516d
ToppCell	facs-Marrow-T-cells-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.02e-04	151	27	3	b52bb3b88e9a6473f571053537b8beb418678539
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.15e-04	157	27	3	0673c7161c25feceee8f1e5fd237171576c42c6b
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.15e-04	157	27	3	d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.33e-04	165	27	3	9acf03b5a20170721380045b5c268825e8f315dd
ToppCell	droplet-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.33e-04	165	27	3	3cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCell	droplet-Marrow-BM-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.35e-04	166	27	3	019d365df44c3bbd88c1f4bdceb3de0ff76d3e8d
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-proerythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.35e-04	166	27	3	a1211afc1197d078eb3db0d0f788ecaf4419aa5b
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.38e-04	167	27	3	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.40e-04	168	27	3	3611605114f6b668b44728d6563cd02389e106af
ToppCell	Immune_cells-Neutrophils\|Immune_cells / Lineage and Cell class	ANXA1 SYNE1 DHRS7	1.40e-04	168	27	3	3539f802fe0143da1462df0618f78f9f15143f71
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.40e-04	168	27	3	faaba5ac01c2ebe380f56559374a121979a85a13
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.40e-04	168	27	3	c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	e0076aa61b4ef3f836f5750005d0469d3982eb6d
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	2341eddfedaad8cee779c37bb87f7def058588ca
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	f38b52972a6c492ce2fd520a26bb3fc8db23bf85
ToppCell	facs-Marrow-Granulocytes-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	94871936ccfc73b56d425373b989b87c059d4493
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	1000eaf5158596b4898bedcc802b31db76b05a48
ToppCell	facs-Marrow-Granulocytes-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	ee1969755180df58d32904e2bb4192da9373d03e
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	5320da1d61806b53e0bd96bbdfdb8fd69246681b
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.43e-04	169	27	3	83b854fa8fd9017df8f9207d9ced260eee98e8c1
ToppCell	droplet-Spleen-nan-3m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTLN ANXA1 SYNE1	1.45e-04	170	27	3	dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	OBSCN SYNE1 KIAA1217	1.48e-04	171	27	3	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.48e-04	171	27	3	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.48e-04	171	27	3	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.48e-04	171	27	3	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	droplet-Marrow-BM-1m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.48e-04	171	27	3	8a0c08f0aa3a80cd6346c81deb242e430ebd897b
ToppCell	droplet-Marrow-nan-3m-Hematologic-proerythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.50e-04	172	27	3	cfcfa7eeff1805bedf10a3c07826459914c3e872
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.53e-04	173	27	3	0f9784b30c81a4a4940e0623cec60d596e9985d2
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1H3 ARHGEF10L GBGT1	1.53e-04	173	27	3	a37f38478473290fe35aea8684befc3bf95b161f
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.53e-04	173	27	3	60f79e0698a7cf7516690fb20f1b82ee46547699
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NR1H3 MDN1 UBR4	1.55e-04	174	27	3	d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR1H3 FAT1 GBGT1	1.55e-04	174	27	3	a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADGRF4 TDO2 ANXA1	1.61e-04	176	27	3	cd4b9211652596c42e7af318bcd464681daebb10
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 TDO2 SYNE1	1.61e-04	176	27	3	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	droplet-Marrow-nan-21m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.61e-04	176	27	3	f7d8eb90489a6d22240179abeb0aa16ac24615d3
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.63e-04	177	27	3	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.63e-04	177	27	3	15d1de38e4f1a0d4a786d83ee92240f44bdff006
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.63e-04	177	27	3	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA1 SYNE1 DHRS7	1.63e-04	177	27	3	b41e975e8368e2618b015be095efe8c0e001c78b
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	NR1H3 CNTLN KIAA1217	1.72e-04	180	27	3	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	JCAD SYNE1 KIAA1217	1.74e-04	181	27	3	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRF4 FAT1 TDO2	1.74e-04	181	27	3	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	1.74e-04	181	27	3	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	1.74e-04	181	27	3	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1H3 ARHGEF10L GBGT1	1.77e-04	182	27	3	be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCell	10x5'v1-week_17-19-Myeloid_DC-DC-tDC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	BTBD16 ANXA1 DHRS7	1.77e-04	182	27	3	ad5c99ec62cdab347d3a03c971d981e3b924020c
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1H3 ARHGEF10L GBGT1	1.77e-04	182	27	3	74dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANXA1 SYNE1 DHRS7	1.80e-04	183	27	3	90c66ffd2c1f87c91f9a9886e28aeec542f9df85
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	JCAD SYNE1 KIAA1217	1.86e-04	185	27	3	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	JCAD FAT1 KIAA1217	1.92e-04	187	27	3	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	JCAD SYNE1 KIAA1217	1.92e-04	187	27	3	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	Control-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	FAT1 SYNE1 KIAA1217	1.95e-04	188	27	3	88b3415e33db81726dd29c1f50c886e057af50a0
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	JCAD SYNE1 KIAA1217	1.98e-04	189	27	3	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	FAT1 SYNE1 KIAA1217	2.01e-04	190	27	3	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD SYNE1 KIAA1217	2.01e-04	190	27	3	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD SYNE1 KIAA1217	2.04e-04	191	27	3	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	JCAD SYNE1 KIAA1217	2.04e-04	191	27	3	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	JCAD SYNE1 KIAA1217	2.04e-04	191	27	3	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	droplet-Heart\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN JCAD SYNE1	2.08e-04	192	27	3	67a7e07a11091120edbccf739836235c422ec9c6
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD SYNE1 UBR4	2.08e-04	192	27	3	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	JCAD SYNE1 KIAA1217	2.11e-04	193	27	3	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD SYNE1 KIAA1217	2.14e-04	194	27	3	660535b492445063d965095a50e1e299ce04c50a
ToppCell	BLOOD--(1)_EM_CTLs\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANXA1 SYNE1 DHRS7	2.14e-04	194	27	3	66583c6cff3814902d6babdea3a2ae962decde65
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	2.14e-04	194	27	3	1374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell	T/NK_cells-CD8+_Naive_T_cell\|World / Lineage and Cell class	ANXA1 SYNE1 DHRS7	2.17e-04	195	27	3	43f11068beea076e9caeb1572215c3f65c9308e1
ToppCell	BLOOD--(1)_T_cell-(1)_EM_CTLs\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANXA1 SYNE1 DHRS7	2.17e-04	195	27	3	7df67ad5c62235474ee56ea07a957253d45f066b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LPAR3 FAT1 KIAA1217	2.17e-04	195	27	3	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	JCAD SYNE1 KIAA1217	2.17e-04	195	27	3	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	2.20e-04	196	27	3	34e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCell	10x5'-Liver-Lymphocytic_NK-NK_CD16\|Liver / Manually curated celltypes from each tissue	ANXA1 SYNE1 DHRS7	2.20e-04	196	27	3	e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	2.20e-04	196	27	3	3cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT1 ANXA1 ARHGEF10L	2.20e-04	196	27	3	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	2.20e-04	196	27	3	8f82e01ca50aa4cd6149547505b4474a02fad618
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD SYNE1 KIAA1217	2.20e-04	196	27	3	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	JCAD SYNE1 KIAA1217	2.20e-04	196	27	3	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ANXA1 SYNE1	2.20e-04	196	27	3	023477a499a2c190f363cfdbc9d9c646733a6541
ToppCell	proximal-Endothelial-Capillary-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	JCAD MFAP3 KIAA1217	2.24e-04	197	27	3	ddb8ea895f0f34d4f20a0740b708fa0f3e378801
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRF4 FAT1 ANXA1	2.24e-04	197	27	3	fb272c9c60ee3d980e528044dc567b4925a23da6
ToppCell	proximal-Endothelial-Capillary\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	JCAD MFAP3 KIAA1217	2.24e-04	197	27	3	53baef54bd85c60ae24a3c163b3a3d937fb6ff0b
ToppCell	proximal-3-Endothelial-Capillary\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	JCAD MFAP3 KIAA1217	2.24e-04	197	27	3	a1a61c03d67272693ec23e0d15f0a12bf618e2da
ToppCell	NS-critical-LOC-Myeloid-Macrophage\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NR1H3 CNTLN ARHGEF10L	2.24e-04	197	27	3	5fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRF4 FAT1 ANXA1	2.24e-04	197	27	3	61c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGRF4 FAT1 ANXA1	2.24e-04	197	27	3	dcabea5c50c133c9a4e294e447462d0393174ea7
Drug	thiophenone	TDO2 SYNE1	1.35e-06	2	27	2	CID009548690
Drug	acyclovir	FXR1 TDO2 FMR1 ANXA1	1.33e-05	124	27	4	CID000002022
Disease	malignant pleural mesothelioma (implicated_via_orthology)	FXR1 FMR1	2.42e-06	3	27	2	DOID:7474 (implicated_via_orthology)
Disease	fragile X syndrome (implicated_via_orthology)	FXR1 FMR1	2.42e-06	3	27	2	DOID:14261 (implicated_via_orthology)
Disease	Colorectal Carcinoma	OBSCN FAT1 ARNT SYNE1 ZMYM4 ARHGEF10L	3.43e-05	702	27	6	C0009402
Disease	QRS duration, response to sulfonylurea	CNTLN MDN1	2.02e-04	23	27	2	EFO_0005055, EFO_0007922
Disease	Colorectal Neoplasms	FAT1 ARNT SYNE1	2.03e-03	277	27	3	C0009404
Disease	Malignant neoplasm of breast	OBSCN ADGRF4 FXR1 SYNE1 UBR4	2.62e-03	1074	27	5	C0006142
Disease	Fatty Liver	NR1H3 DHRS7	2.94e-03	88	27	2	C0015695
Disease	Steatohepatitis	NR1H3 DHRS7	2.94e-03	88	27	2	C2711227
Disease	Squamous cell carcinoma of esophagus	FAT1 ANXA1	3.42e-03	95	27	2	C0279626

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILRMAVSHMKSLRGT	ARNT	131	P27540
TRMAVMRKVSFLHRK	ARHGEF10L	261	Q9HCE6
HRERAMMTMAVLSKR	ERVK-9	666	Q9UKH3
ISRMERDITMKRHLI	CNTLN	1136	Q9NXG0
MIMSNTHKARLERRV	BTBD16	1	Q32M84
DHKIRDALRMRMSSL	ADGRF4	656	Q8IZF3
SHKMTTSRCVRLMLI	DHRS7	261	Q9Y394
RMLMKLVSLRTLSSV	NR1H3	406	Q13133
TRHKALIRIMVSRSE	ANXA1	291	P04083
LEMKLTMRLRTYSTH	FAT1	3851	Q14517
HLMKMLVRQRRSLTT	MDN1	4231	Q9NU22
DMHLRSIRTKLMLMS	FXR1	186	P51114
SRAITQGHRIMVMRS	FLYWCH1	641	Q4VC44
RMKEVSSVSRMRVLS	JCAD	1261	Q9P266
KVLTSSSRLHMMVRR	PDZD7	151	Q9H5P4
IMRMRVHSNLTKKRV	LPAR3	131	Q9UBY5
NVTRLCMMSSHLRKT	MFAP3	166	P55082
GTVHRLMLRRTCSTM	OBSCN	2431	Q5VST9
HVSSVRVKMMTTLRT	ATR	1166	Q13535
DMHFRSLRTKLSLIM	FMR1	186	Q06787
MRRMETISQHIAKRA	GBGT1	181	Q8N5D6
HRERAMMTMAVLSKR	ERVK-24	556	P61566
HRERAMMTMAVLSKR	ERVK-7	556	P61567
LLLTVYSMRRHTSKM	TMEM63B	216	Q5T3F8
KTEHMTRTLRGVMRV	ILF3	81	Q12906
HRERAMMTMVVLSKR	ERVK-21	666	P61565
TLTVLAERMSTIRMK	SYNE1	6046	Q8NF91
RNMLKVVSRMHRVSV	TDO2	106	P48775
RVRSMTDVLTMLRRH	KIAA1217	806	Q5T5P2
VHLVVMRLLSVFMSR	UBR4	3051	Q5T4S7
HVMRRTRTLKYSTKM	ZMYM4	1406	Q5VZL5