Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	betaine-homocysteine S-methyltransferase activity	BHMT BHMT2	2.65e-06	2	33	2	GO:0047150
GeneOntologyMolecularFunction	S-methyltransferase activity	BHMT BHMT2	1.44e-04	11	33	2	GO:0008172
GeneOntologyMolecularFunction	ephrin receptor activity	EPHA2 NTRK1	4.45e-04	19	33	2	GO:0005003
GeneOntologyMolecularFunction	UDP-galactosyltransferase activity	WDFY3 PLOD3	1.27e-03	32	33	2	GO:0035250
GeneOntologyMolecularFunction	galactosyltransferase activity	WDFY3 PLOD3	1.52e-03	35	33	2	GO:0008378
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	B3GNT9 WDFY3 PLOD3	2.03e-03	153	33	3	GO:0008194
GeneOntologyMolecularFunction	vitamin binding	KYAT3 GAD2 PLOD3	2.35e-03	161	33	3	GO:0019842
GeneOntologyMolecularFunction	pyridoxal phosphate binding	KYAT3 GAD2	3.86e-03	56	33	2	GO:0030170
GeneOntologyMolecularFunction	vitamin B6 binding	KYAT3 GAD2	3.99e-03	57	33	2	GO:0070279
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors	TM7SF2 COX15	4.71e-03	62	33	2	GO:0016627
GeneOntologyMolecularFunction	hexosyltransferase activity	B3GNT9 WDFY3 PLOD3	5.02e-03	211	33	3	GO:0016758
GeneOntologyMolecularFunction	lyase activity	KYAT3 GAD2 HTD2	5.09e-03	212	33	3	GO:0016829
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EPHA2 NTRK1	5.16e-03	65	33	2	GO:0004714
GeneOntologyMolecularFunction	amino acid binding	GAD2 GRIN3A	6.47e-03	73	33	2	GO:0016597
GeneOntologyBiologicalProcess	aspartate family amino acid biosynthetic process	PLOD3 BHMT BHMT2	5.12e-06	22	32	3	GO:0009067
GeneOntologyBiologicalProcess	amino acid biosynthetic process	GAD2 PLOD3 BHMT BHMT2	9.27e-06	86	32	4	GO:0008652
GeneOntologyBiologicalProcess	non-proteinogenic amino acid metabolic process	KYAT3 GAD2 PLOD3 BHMT	9.70e-06	87	32	4	GO:0170041
GeneOntologyBiologicalProcess	L-amino acid metabolic process	KYAT3 GAD2 PLOD3 BHMT BHMT2	1.60e-05	208	32	5	GO:0170033
GeneOntologyBiologicalProcess	alpha-amino acid metabolic process	KYAT3 GAD2 PLOD3 BHMT BHMT2	3.95e-05	251	32	5	GO:1901605
GeneOntologyBiologicalProcess	L-methionine salvage	BHMT BHMT2	4.87e-05	7	32	2	GO:0071267
GeneOntologyBiologicalProcess	L-methionine biosynthetic process	BHMT BHMT2	4.87e-05	7	32	2	GO:0071265
GeneOntologyBiologicalProcess	amino acid salvage	BHMT BHMT2	4.87e-05	7	32	2	GO:0043102
GeneOntologyBiologicalProcess	aspartate family amino acid metabolic process	PLOD3 BHMT BHMT2	5.59e-05	48	32	3	GO:0009066
GeneOntologyBiologicalProcess	amino acid metabolic process	KYAT3 GAD2 PLOD3 BHMT BHMT2	1.48e-04	332	32	5	GO:0006520
GeneOntologyBiologicalProcess	methionine biosynthetic process	BHMT BHMT2	1.52e-04	12	32	2	GO:0009086
GeneOntologyBiologicalProcess	proteinogenic amino acid biosynthetic process	PLOD3 BHMT BHMT2	1.66e-04	69	32	3	GO:0170038
GeneOntologyBiologicalProcess	L-amino acid biosynthetic process	PLOD3 BHMT BHMT2	1.73e-04	70	32	3	GO:0170034
GeneOntologyBiologicalProcess	proteinogenic amino acid metabolic process	GAD2 PLOD3 BHMT BHMT2	1.85e-04	185	32	4	GO:0170039
GeneOntologyBiologicalProcess	alpha-amino acid biosynthetic process	PLOD3 BHMT BHMT2	2.30e-04	77	32	3	GO:1901607
GeneOntologyBiologicalProcess	carboxylic acid biosynthetic process	GAD2 PLOD3 HTD2 BHMT BHMT2	2.57e-04	374	32	5	GO:0046394
GeneOntologyBiologicalProcess	organic acid biosynthetic process	GAD2 PLOD3 HTD2 BHMT BHMT2	2.66e-04	377	32	5	GO:0016053
GeneOntologyBiologicalProcess	methionine metabolic process	BHMT BHMT2	2.76e-04	16	32	2	GO:0006555
GeneOntologyBiologicalProcess	non-proteinogenic amino acid biosynthetic process	GAD2 PLOD3	3.13e-04	17	32	2	GO:0170043
GeneOntologyBiologicalProcess	modified amino acid metabolic process	SLCO4A1 PLOD3 BHMT BHMT2	3.46e-04	218	32	4	GO:0006575
GeneOntologyBiologicalProcess	amino-acid betaine metabolic process	BHMT BHMT2	3.51e-04	18	32	2	GO:0006577
GeneOntologyBiologicalProcess	prepulse inhibition	BACE1 GRIN3A	4.35e-04	20	32	2	GO:0060134
GeneOntologyBiologicalProcess	sulfur amino acid biosynthetic process	BHMT BHMT2	4.81e-04	21	32	2	GO:0000097
GeneOntologyBiologicalProcess	S-adenosylmethionine metabolic process	BHMT BHMT2	5.28e-04	22	32	2	GO:0046500
GeneOntologyBiologicalProcess	small molecule biosynthetic process	TM7SF2 GAD2 PLOD3 HTD2 BHMT BHMT2	5.30e-04	676	32	6	GO:0044283
GeneOntologyBiologicalProcess	notochord development	GDF3 EPHA2	6.30e-04	24	32	2	GO:0030903
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of pain	BACE1 NTRK1	7.40e-04	26	32	2	GO:0050966
GeneOntologyBiologicalProcess	carboxylic acid metabolic process	KYAT3 GAD2 PLOD3 HTD2 BHMT ETFDH BHMT2	8.76e-04	1035	32	7	GO:0019752
GeneOntologyBiologicalProcess	oxoacid metabolic process	KYAT3 GAD2 PLOD3 HTD2 BHMT ETFDH BHMT2	9.97e-04	1058	32	7	GO:0043436
GeneOntologyBiologicalProcess	organic acid metabolic process	KYAT3 GAD2 PLOD3 HTD2 BHMT ETFDH BHMT2	1.03e-03	1064	32	7	GO:0006082
GeneOntologyBiologicalProcess	sulfur amino acid metabolic process	BHMT BHMT2	1.75e-03	40	32	2	GO:0000096
GeneOntologyBiologicalProcess	cellular metabolic compound salvage	BHMT BHMT2	1.75e-03	40	32	2	GO:0043094
GeneOntologyBiologicalProcess	startle response	BACE1 GRIN3A	1.84e-03	41	32	2	GO:0001964
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception of pain	BACE1 NTRK1	2.02e-03	43	32	2	GO:0062149
MousePheno	split notochord	GDF3 EPHA2	5.41e-05	7	23	2	MP:0004713
Domain	Betaine-hCys_S-MeTrfase_BHMT	BHMT BHMT2	2.84e-06	2	32	2	IPR017226
Domain	-	BHMT BHMT2	8.52e-06	3	32	2	3.20.20.330
Domain	S-methyl_trans	BHMT BHMT2	8.52e-06	3	32	2	PF02574
Domain	HCY_dom	BHMT BHMT2	8.52e-06	3	32	2	IPR003726
Domain	HCY	BHMT BHMT2	8.52e-06	3	32	2	PS50970
Domain	-	KYAT3 GAD2	1.63e-03	35	32	2	3.90.1150.10
Domain	PyrdxlP-dep_Trfase_major_sub2	KYAT3 GAD2	1.73e-03	36	32	2	IPR015422
Domain	-	KYAT3 GAD2	2.03e-03	39	32	2	3.40.640.10
Domain	PyrdxlP-dep_Trfase	KYAT3 GAD2	2.24e-03	41	32	2	IPR015424
Domain	PyrdxlP-dep_Trfase_major_sub1	KYAT3 GAD2	2.24e-03	41	32	2	IPR015421
Pathway	WP_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS	GAD2 BHMT BHMT2	1.30e-04	54	26	3	MM15848
Pathway	WP_TRANSSULFURATION_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS	GAD2 BHMT BHMT2	2.47e-04	67	26	3	M39710
Pubmed	Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.	BHMT BHMT2	8.73e-07	2	33	2	18230605
Pubmed	Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization.	BHMT BHMT2	8.73e-07	2	33	2	18457970
Pubmed	Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes.	BHMT BHMT2	8.73e-07	2	33	2	26213999
Pubmed	Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes.	BHMT BHMT2	8.73e-07	2	33	2	11087663
Pubmed	Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease.	BHMT BHMT2	8.73e-07	2	33	2	12818402
Pubmed	ProNGF increases breast tumor aggressiveness through functional association of TrkA with EphA2.	EPHA2 NTRK1	2.62e-06	3	33	2	30771434
Pubmed	Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation.	BHMT BHMT2	2.62e-06	3	33	2	25846410
Pubmed	Evidence of interaction between genes in the folate/homocysteine metabolic pathway in controlling risk of non-syndromic oral cleft.	BHMT BHMT2	2.62e-06	3	33	2	29356306
Pubmed	New evidence for the role of cystathionine beta-synthase in non-syndromic cleft lip with or without cleft palate.	BHMT BHMT2	2.62e-06	3	33	2	21564312
Pubmed	Matrix metalloproteinase-9 participates in NGF-induced α-secretase cleavage of amyloid-β protein precursor in PC12 cells.	BACE1 NTRK1	5.23e-06	4	33	2	21321391
Pubmed	Polymorphisms located in the region containing BHMT and BHMT2 genes as maternal protective factors for orofacial clefts.	BHMT BHMT2	1.83e-05	7	33	2	20662904
Pubmed	Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules.	ARHGAP32 NTRK1	5.73e-05	12	33	2	12446789
Pubmed	Associations of folate and choline metabolism gene polymorphisms with orofacial clefts.	BHMT BHMT2	5.73e-05	12	33	2	19737740
Pubmed	A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles.	BACE1 NTRK1	7.89e-05	14	33	2	27707970
Pubmed	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	BHMT BHMT2	7.89e-05	14	33	2	23378610
Pubmed	Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.	BHMT BHMT2	7.89e-05	14	33	2	30753104
Pubmed	118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects.	BHMT BHMT2	7.89e-05	14	33	2	19493349
Pubmed	Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism.	BHMT BHMT2	1.18e-04	17	33	2	20458436
Pubmed	Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.	GAD2 NTRK1	1.18e-04	17	33	2	26257608
Pubmed	Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm.	BHMT BHMT2	1.18e-04	17	33	2	18635682
Pubmed	High-throughput multiplex single-nucleotide polymorphism (SNP) analysis in genes involved in methionine metabolism.	BHMT BHMT2	1.18e-04	17	33	2	18427977
Pubmed	Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure.	GAD2 NTRK1	1.32e-04	18	33	2	38505753
Pubmed	Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain.	GAD2 NTRK1	1.64e-04	20	33	2	36334588
Pubmed	SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice.	NTRK1 WNT6	1.99e-04	22	33	2	37039821
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	GAD2 WNT6 BHMT BHMT2	2.65e-04	331	33	4	20634891
Pubmed	Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study.	BHMT BHMT2	3.49e-04	29	33	2	19048631
Pubmed	WDFY4 is required for cross-presentation in response to viral and tumor antigens.	PLOD3 NOMO2 MYO1F	4.38e-04	156	33	3	30409884
Pubmed	Liver and brain differential expression of one-carbon metabolism genes during ontogenesis.	BHMT BHMT2	4.53e-04	33	33	2	34702858
Pubmed	Diverse Central Projection Patterns of Retinal Ganglion Cells.	GAD2 NTRK1	5.09e-04	35	33	2	28228269
Pubmed	Genome-wide association study of selenium concentrations.	BHMT BHMT2	5.09e-04	35	33	2	25343990
Pubmed	Single-cell transcriptomic analysis of mouse neocortical development.	NFE2L3 GAD2 GRIN3A	5.62e-04	170	33	3	30635555
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	EPHA2 NTRK1	6.66e-04	40	33	2	30898150
Pubmed	Proteomic identification of brain proteins that interact with dynein light chain LC8.	GRIN3A DYNC1H1	7.34e-04	42	33	2	14760703
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	WDR33 DYNC1H1	7.69e-04	43	33	2	34672947
Pubmed	Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.	DYNC1H1 NTRK1	8.06e-04	44	33	2	38351062
Pubmed	Malformation of the Posterior Cerebellar Vermis Is a Common Neuroanatomical Phenotype of Genetically Engineered Mice on the C57BL/6 Background.	GAD2 NTRK1	8.43e-04	45	33	2	29043563
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFE2L3 SLCO4A1 ARHGAP32 EPHA2	7.92e-06	173	33	4	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFE2L3 SLCO4A1 ARHGAP32 EPHA2	7.92e-06	173	33	4	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2L3 SLCO4A1 ARHGAP32 EPHA2	9.06e-06	179	33	4	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NTRK1 BHMT BHMT2	1.13e-04	127	33	3	ca77f85502dd66f3cb4b15cf80f755104ca1e6ff
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NTRK1 BHMT BHMT2	1.13e-04	127	33	3	25d0b28c9df2d10fbcdb0aca47b75bf5c7c9c430
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NTRK1 BHMT BHMT2	1.13e-04	127	33	3	b27d5141e661a4c6924aa6d7c5b046f9ae49955d
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NTRK1 BHMT BHMT2	1.13e-04	127	33	3	352d44233a93c926aeb7c5fad49965fd82b873ca
ToppCell	droplet-Liver-Npc-21m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 EPHX4 BHMT	1.60e-04	143	33	3	0cd332c128710291a39957d3da22953352f5c382
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1\|Striatum / BrainAtlas - Mouse McCarroll V32	NFE2L3 B3GNT9 CEACAM20	1.63e-04	144	33	3	9d6133558728fa148050eb4f0be33756d71310b0
ToppCell	droplet-Liver-Npc-21m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 EPHX4 BHMT	1.70e-04	146	33	3	24e63124116b9a6796ae0495fc69dc6b6af28c38
ToppCell	droplet-Liver-Npc-21m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 EPHX4 BHMT	1.70e-04	146	33	3	ae43d418492177546b7f85afffb4287d40815f88
ToppCell	droplet-Liver-Npc-18m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 BHMT ETFDH	1.88e-04	151	33	3	86efabf27c264c856dca1cffacb16cef52e9863c
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 B3GNT9 EPHA2	2.11e-04	157	33	3	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 B3GNT9 EPHA2	2.11e-04	157	33	3	66a191cef4aa00811bb04462310d012610006f85
ToppCell	droplet-Liver-Hepatocytes-21m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 BHMT BHMT2	2.39e-04	164	33	3	c9866a289e120be4066e66275c3beb97ba67cca4
ToppCell	droplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2L3 ARHGAP32 EPHA2	2.48e-04	166	33	3	6e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 BHMT BHMT2	2.48e-04	166	33	3	4b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFE2L3 ARHGAP32 EPHA2	2.48e-04	166	33	3	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2L3 ARHGAP32 EPHA2	2.48e-04	166	33	3	4fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFE2L3 ARHGAP32 EPHA2	2.48e-04	166	33	3	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 GRIN3A EPHA2	2.48e-04	166	33	3	9fa8510adfa3050ee182b4b71e5655abb9bb8a76
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KYAT3 BHMT BHMT2	2.48e-04	166	33	3	d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2L3 SLCO4A1 EPHA2	2.61e-04	169	33	3	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF3 MYO1F PSD4	2.66e-04	170	33	3	c4f00c1acde1d3b521101e469101d10fd257653e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF3 MYO1F PSD4	2.66e-04	170	33	3	d3c1edaf0190d8927578043c372dba7477e75e14
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 ARHGAP32 EPHA2	2.71e-04	171	33	3	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BHMT ETFDH BHMT2	2.75e-04	172	33	3	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BHMT ETFDH BHMT2	2.75e-04	172	33	3	9adfb4a65669cc536343616637058d0a4728013f
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BHMT ETFDH BHMT2	2.75e-04	172	33	3	8aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCell	normal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	NOMO2 WNT6 MYO1F	2.80e-04	173	33	3	1e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFE2L3 ARHGAP32 EPHA2	2.90e-04	175	33	3	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAD2 CEACAM20 BHMT	2.99e-04	177	33	3	8dbef0005095c01a806d8c7f723dc48a4650efec
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF3 BHMT BHMT2	2.99e-04	177	33	3	6248c0dcad302de61a66163ee84b3b79096150d7
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA BHMT BHMT2	3.04e-04	178	33	3	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA BHMT BHMT2	3.15e-04	180	33	3	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA BHMT BHMT2	3.15e-04	180	33	3	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 PAPPA NTRK1	3.25e-04	182	33	3	fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA BHMT BHMT2	3.30e-04	183	33	3	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.30e-04	183	33	3	439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.35e-04	184	33	3	23515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GAD2 GRIN3A BHMT	3.35e-04	184	33	3	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NFE2L3 PAPPA B3GNT9	3.35e-04	184	33	3	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT9 GRIN3A NTRK1	3.41e-04	185	33	3	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA BHMT BHMT2	3.41e-04	185	33	3	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA WDFY3 BHMT	3.52e-04	187	33	3	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.52e-04	187	33	3	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	wk_08-11-Epithelial-Distal_epithelial-epi-tip_early\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NFE2L3 TM7SF2 EPHA2	3.52e-04	187	33	3	5f9696097741b6e2b7b410c15c6b5ed883ed5eb2
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAPPA BHMT BHMT2	3.52e-04	187	33	3	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	wk_08-11-Epithelial-Distal_epithelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NFE2L3 TM7SF2 EPHA2	3.52e-04	187	33	3	eefffc2c6f7fa708a96e6bf07c6ce4e6c2e90847
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	PAPPA BHMT BHMT2	3.52e-04	187	33	3	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA BHMT BHMT2	3.63e-04	189	33	3	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA BHMT BHMT2	3.63e-04	189	33	3	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.63e-04	189	33	3	06c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFE2L3 BHMT BHMT2	3.63e-04	189	33	3	0739baad9a7da511dd3d7249f84299aee88370a1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.68e-04	190	33	3	d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GDF3 BHMT BHMT2	3.68e-04	190	33	3	103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCell	ILEUM-non-inflamed-(8)_Activated_fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	BACE1 EPHA2 BHMT2	3.68e-04	190	33	3	39fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.74e-04	191	33	3	de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA BHMT BHMT2	3.74e-04	191	33	3	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	HSPCs-Gran/Mono_prog.\|HSPCs / Lineage and Cell class	KYAT3 PLOD3 MYO1F	3.74e-04	191	33	3	54620502e6aea0a615b664e861e0044dd9e0ad91
ToppCell	15-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	NFE2L3 PAPPA WNT6	3.74e-04	191	33	3	409e12d2bb26b6d2ed025304ca6ace07df16638a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA BHMT BHMT2	3.74e-04	191	33	3	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.74e-04	191	33	3	9c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.80e-04	192	33	3	dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAD2 CEACAM20 BHMT	3.80e-04	192	33	3	5692bd57093852d442400383850f416c497dcc7d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	53bcd50892c379b2a571751f6eb1062436339fe7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	4979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	8b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	2c15186d15545804cc262da9137ab825609d4b2c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	2189da4b727e25e62669d7b9257f06493be21a27
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.86e-04	193	33	3	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	NFE2L3 EPHA2 WNT6	3.92e-04	194	33	3	784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.92e-04	194	33	3	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 PAPPA GRIN3A	3.92e-04	194	33	3	1bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PAPPA WNT6 MYO1F	4.09e-04	197	33	3	7870c0651caefb0ed13d9f9dab43b5f24d6a9efc
ToppCell	TCGA-Colorectal-Primary_Tumor\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NFE2L3 SLCO4A1 EPHX4	4.22e-04	199	33	3	c7d6a8398f2419b726a0461585d1ee0561654e3b
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NFE2L3 EPHA2 WNT6	4.22e-04	199	33	3	f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADAMTS16 NTRK1 MYO1F	4.22e-04	199	33	3	892ca0dc9928d3985bf99de8afc68c06d22e6e2e
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NFE2L3 SLCO4A1 EPHX4	4.22e-04	199	33	3	85b3b1ad01368dae4adbc9da7efc148e49992f69
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NFE2L3 EPHA2 WNT6	4.22e-04	199	33	3	c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	347a510755374c6a66acee326565dfc447993f18
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-GXYLT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	fe63aa1febd2bf650a7dd4e8b4420063580644ba
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	8d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	05bcde6ce8f1354ef65e4eb9cbd963a92108081c
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	6a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-GXYLT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	37728d83b246dd70933d1f52f938bc1c401df7b9
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	1a04331862079092bc04b1010aa9228c0fa3d8c5
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-GXYLT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	cafa1b46d0b052fca6191ad99d5862a07d0a1fd2
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	fb56d430957e73fba17db7bc0127ecf3577e0867
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	2131c8e7fa054b79906eaf60536da892438b09cd
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 PAPPA GRIN3A	4.28e-04	200	33	3	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
Drug	Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A	GAD2 PAPPA WDR33 NTRK1 MYO1F	7.49e-06	196	32	5	3604_UP
Drug	4-acetylpyridine	GAD2 DYNC1H1	1.91e-05	5	32	2	CID000014282
Drug	L-Methionine	BHMT BHMT2	1.91e-05	5	32	2	DB00134
Drug	Vitamin U	BHMT BHMT2	1.91e-05	5	32	2	ctd:D014814
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	NFE2L3 CEACAM20 NYNRIN	2.98e-04	120	32	3	EFO_0004611, EFO_0004639
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	NFE2L3 CEACAM20 NYNRIN	4.40e-04	137	32	3	EFO_0004611, EFO_0008591
Disease	selenium measurement	BHMT BHMT2	4.54e-04	29	32	2	EFO_0006331
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	NFE2L3 CEACAM20 ETFDH	5.09e-04	144	32	3	EFO_0004611, EFO_0020943
Disease	monocyte percentage of leukocytes	NFE2L3 GAD2 WDFY3 ETFDH MYO1F	1.06e-03	731	32	5	EFO_0007989
Disease	cholesterol in medium LDL measurement	CEACAM20 NYNRIN	1.30e-03	49	32	2	EFO_0022224
Disease	total lipids in medium LDL	CEACAM20 NYNRIN	1.46e-03	52	32	2	EFO_0022180
Disease	cholesterol to total lipids in large HDL percentage	NFE2L3 ETFDH	1.63e-03	55	32	2	EFO_0022234
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	NFE2L3 CEACAM20 NYNRIN	1.84e-03	225	32	3	EFO_0008317, EFO_0010351
Disease	low density lipoprotein cholesterol measurement, physical activity	NFE2L3 NYNRIN	2.34e-03	66	32	2	EFO_0003940, EFO_0004611
Disease	Schizophrenia	BACE1 GAD2 ARHGAP32 GRIN3A NTRK1	2.44e-03	883	32	5	C0036341
Disease	cholesteryl ester measurement	CEACAM20 NYNRIN ETFDH	2.69e-03	257	32	3	EFO_0010351
Disease	Manic Disorder	GAD2 NTRK1	2.70e-03	71	32	2	C0024713
Disease	very low density lipoprotein cholesterol measurement	CEACAM20 NYNRIN MYO1F	2.78e-03	260	32	3	EFO_0008317
Disease	Manic	GAD2 NTRK1	3.25e-03	78	32	2	C0338831
Disease	schizophrenia (is_implicated_in)	GAD2 NTRK1	3.25e-03	78	32	2	DOID:5419 (is_implicated_in)
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	NFE2L3 CEACAM20 ETFDH	3.29e-03	276	32	3	EFO_0004612, EFO_0020943
Disease	Depression, Bipolar	GAD2 NTRK1	3.33e-03	79	32	2	C0005587
Disease	sphingomyelin measurement	CEACAM20 DYNC1H1 ETFDH	3.35e-03	278	32	3	EFO_0010118
Disease	fasting blood glucose measurement	SLCO4A1 GAD2 ETFDH	3.67e-03	287	32	3	EFO_0004465
Disease	Papillary thyroid carcinoma	DYNC1H1 NTRK1	3.93e-03	86	32	2	C0238463
Disease	hepatocellular carcinoma (is_marker_for)	PLOD3 BHMT BHMT2	4.19e-03	301	32	3	DOID:684 (is_marker_for)
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	NFE2L3 CEACAM20 ETFDH	4.27e-03	303	32	3	EFO_0004612, EFO_0020945

Protein segments in the cluster

Peptide	Gene	Start	Entry
WGSGLDMHTKPWVRA	BHMT	331	Q93088
PWLLLWMGAGVLPAH	BACE1	6	P56817
HTMGKGHQRPWWKVL	CCSMST1	66	Q4G0I0
MGPADSWGHHWMGIL	CEACAM20	1	Q6UY09
MKPRARGWRGLAALW	ADAMTS16	1	Q8TE57
PMLSRHGKLWSNFWG	PLOD3	416	O60568
AWGGGLLMSRKHKWK	GAD2	366	Q05329
MLRGGRRGQLGWHSW	NTRK1	1	P04629
LMWCLVPWRGTLGIH	NOMO2	1231	Q5JPE7
IGHDWGGMIAWLIAI	EPHX4	166	Q8IUS5
LGWHKWIIAPKGFMA	GDF3	276	Q9NR23
MFPLISSHHLWWGGL	HTD2	1	P86397
MKHLKRWWSAGGGLL	NFE2L3	1	Q9Y4A8
WPWDKEALMHLGGIV	PAPPA	531	Q13219
MPPKVLSTWWRGKHG	ARHGAP32	291	A7KAX9
PMWTRLGSWQGGKIV	GRIN3A	476	Q8TCU5
KLLVSGWWGMVRHPN	TM7SF2	336	O76062
MGLPGIHEWQHWLSL	OR56B4	21	Q8NH76
WILRGMEPWTLKHKG	ETFDH	476	Q16134
SWGSGLDMHTKPWIR	BHMT2	321	Q9H2M3
LGWLTHPYGKGWDLM	EPHA2	41	P29317
GRWVMLKNVHLAPGW	DYNC1H1	4091	Q14204
WRKGWLSRGMKGRVL	COX15	171	Q7KZN9
MLGLPWKGGLSWALL	CST9L	1	Q9H4G1
GWKLGWSIGPNHLIK	KYAT3	286	Q6YP21
LRLLGWWPGMQEHVK	NYNRIN	1566	Q9P2P1
TPWGKRGWKMFHTLL	PSD4	796	Q8NDX1
GTFWKHWPSILLKGL	TRPT1	131	Q86TN4
SGHKPRWLGWGVLLM	SLCO4A1	166	Q96BD0
DIWLMWRLLHGPHGP	B3GNT9	371	Q6UX72
GLWGPPIGSHLDKWM	WDFY3	2356	Q8IZQ1
HVGGLWWAVGSPLVM	WNT6	21	Q9Y6F9
GMIWSLAWHPLGHIL	WDR33	376	Q9C0J8
LMEDPSGWWKGRLHG	MYO1F	1071	O00160