Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	FOXN1 HNF1A ZNF444 DBX2 SOX17 ISL2 GBX1 RFX6 HIF3A DMBX1 RXRA PGR TLX2 HIVEP3 FOXP4 KMT2D BCL11B NKX2-4 MIXL1 NR5A2 SKOR1 NR5A1 LYL1 OLIG2	5.04e-05	1412	141	24	GO:0000981
GeneOntologyMolecularFunction	protein domain specific binding	SHANK1 WHRN EVL ILK ATN1 RXRA PTK2 IKZF4 DLGAP3 SH3PXD2B ATXN1 ABI2 CASKIN1 STRN4 RIMS1 OLIG2 INPP5J	1.50e-04	875	141	17	GO:0019904
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HNF1A ZNF444 SOX17 ISL2 RFX6 HIF3A KDM6B RXRA IKZF4 PGR TLX2 HIVEP3 FOXP4 BCL11B NKX2-4 MIXL1 NR5A2 SKOR1 NR5A1 LYL1 OLIG2	2.32e-04	1271	141	21	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HNF1A ZNF444 SOX17 RFX6 HIF3A KDM6B RXRA IKZF4 PGR TLX2 HIVEP3 FOXP4 BCL11B NKX2-4 MIXL1 NR5A2 SKOR1 NR5A1 LYL1 OLIG2	4.71e-04	1244	141	20	GO:0000978
GeneOntologyMolecularFunction	SH3 domain binding	SHANK1 EVL ILK ABI2 RIMS1 INPP5J	5.39e-04	143	141	6	GO:0017124
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HNF1A ZNF444 SOX17 GBX1 RFX6 HIF3A KDM6B DMBX1 RXRA IKZF4 PGR TLX2 HIVEP3 FOXP4 BCL11B NKX2-4 MIXL1 NR5A2 SKOR1 NR5A1 LYL1 OLIG2	5.74e-04	1459	141	22	GO:0000977
GeneOntologyMolecularFunction	cytoskeletal anchor activity	GAS2L3 ABI2 SYN1	6.26e-04	24	141	3	GO:0008093
GeneOntologyMolecularFunction	nuclear receptor activity	RXRA PGR NR5A2 NR5A1	8.55e-04	60	141	4	GO:0004879
GeneOntologyMolecularFunction	transcription factor binding	HNF1A TRIP6 PPRC1 BCAS3 SOX17 HDAC7 JMJD1C RXRA IKZF4 PGR MIXL1 TLE4 NR5A2 NR5A1	9.05e-04	753	141	14	GO:0008134
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	RXRA PGR NR5A2 NR5A1	9.10e-04	61	141	4	GO:0098531
GeneOntologyBiologicalProcess	cell migration involved in gastrulation	SOX17 MIXL1 AMOT CRB2	9.31e-06	20	141	4	GO:0042074
GeneOntologyBiologicalProcess	neuron development	SHANK1 WHRN SEMA6B EVL ILK PSD PAK4 ISL2 GBX1 ARTN MFRP PTK2 TLX2 SEMA4C LIMK1 BCL11B CELSR2 ABI2 RP1L1 SYN1 RIMS1 OLIG2 SDK1 INPP5J CRB2	1.83e-05	1463	141	25	GO:0048666
GeneOntologyBiologicalProcess	formation of primary germ layer	HNF1A SOX17 KDM6B TLX2 MIXL1 CHRD CRB2	2.32e-05	124	141	7	GO:0001704
GeneOntologyBiologicalProcess	lymphoid lineage cell migration into thymus	FOXN1 BCL11B	4.64e-05	2	141	2	GO:0097535
GeneOntologyCellularComponent	chromatin	FOXN1 HNF1A DBX2 BCAS3 SOX17 ISL2 GBX1 RFX6 HIF3A ZNF385A FAAP100 JMJD1C DMBX1 RXRA PGR TLX2 FOXP4 H1-8 BCL11B NKX2-4 MIXL1 TONSL NR5A2 SWI5 NR5A1 LYL1 OLIG2	1.84e-06	1480	141	27	GO:0000785
GeneOntologyCellularComponent	dendrite	SHANK1 WHRN RAP1GAP ILK PSD HCN4 ZNF385A SHISA7 PTK2 PGR DLGAP3 ABI2 STRN4 SKOR1 SHARPIN SYN1 INPP5J	6.82e-05	858	141	17	GO:0030425
GeneOntologyCellularComponent	dendritic tree	SHANK1 WHRN RAP1GAP ILK PSD HCN4 ZNF385A SHISA7 PTK2 PGR DLGAP3 ABI2 STRN4 SKOR1 SHARPIN SYN1 INPP5J	7.01e-05	860	141	17	GO:0097447
GeneOntologyCellularComponent	dendritic spine	SHANK1 PSD SHISA7 PTK2 PGR DLGAP3 ABI2 STRN4	2.42e-04	242	141	8	GO:0043197
GeneOntologyCellularComponent	neuron spine	SHANK1 PSD SHISA7 PTK2 PGR DLGAP3 ABI2 STRN4	2.78e-04	247	141	8	GO:0044309
GeneOntologyCellularComponent	cell leading edge	EVL ILK PSD ATN1 BCAS3 SHISA7 PTK2 LIMK1 ABI2 AMOT INPP5J	5.91e-04	500	141	11	GO:0031252
GeneOntologyCellularComponent	contractile actin filament bundle	EVL ILK TRIP6 PTK2 AMOT	7.97e-04	107	141	5	GO:0097517
GeneOntologyCellularComponent	stress fiber	EVL ILK TRIP6 PTK2 AMOT	7.97e-04	107	141	5	GO:0001725
GeneOntologyCellularComponent	actomyosin	EVL ILK TRIP6 PTK2 AMOT	1.19e-03	117	141	5	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	EVL ILK TRIP6 PTK2 AMOT	1.24e-03	118	141	5	GO:0032432
GeneOntologyCellularComponent	postsynapse	SHANK1 WHRN PSD HTR3E SHISA7 PTK2 PGR SEMA4C DLGAP3 LIMK1 ABI2 CASKIN1 STRN4 SYN1 RNF216 RIMS1	1.42e-03	1018	141	16	GO:0098794
GeneOntologyCellularComponent	somatodendritic compartment	SHANK1 WHRN RAP1GAP ILK PSD HCN4 ZNF385A SHISA7 PTK2 PGR DLGAP3 TTBK1 ABI2 STRN4 SKOR1 SHARPIN SYN1 INPP5J	1.56e-03	1228	141	18	GO:0036477
Domain	SH3	SHANK1 TNK1 MIA3 SH3PXD2B ABI2 CASKIN1 MYO1F UBASH3B BAIAP2L2	3.50e-05	216	139	9	SM00326
Domain	SH3	SHANK1 TNK1 MIA3 SH3PXD2B ABI2 CASKIN1 MYO1F UBASH3B BAIAP2L2	3.50e-05	216	139	9	PS50002
Domain	SH3_domain	SHANK1 TNK1 MIA3 SH3PXD2B ABI2 CASKIN1 MYO1F UBASH3B BAIAP2L2	4.04e-05	220	139	9	IPR001452
Domain	NR5_fam	NR5A2 NR5A1	5.50e-05	2	139	2	IPR016355
Domain	Homeobox	HNF1A DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	3.71e-04	234	139	8	PF00046
Domain	Znf_hrmn_rcpt	RXRA PGR NR5A2 NR5A1	3.76e-04	46	139	4	IPR001628
Domain	NUCLEAR_REC_DBD_2	RXRA PGR NR5A2 NR5A1	3.76e-04	46	139	4	PS51030
Domain	NUCLEAR_REC_DBD_1	RXRA PGR NR5A2 NR5A1	3.76e-04	46	139	4	PS00031
Domain	ZnF_C4	RXRA PGR NR5A2 NR5A1	3.76e-04	46	139	4	SM00399
Domain	zf-C4	RXRA PGR NR5A2 NR5A1	3.76e-04	46	139	4	PF00105
Domain	Nuclear_hrmn_rcpt	RXRA PGR NR5A2 NR5A1	3.76e-04	46	139	4	IPR001723
Domain	HOMEOBOX_1	HNF1A DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	3.93e-04	236	139	8	PS00027
Domain	HOX	HNF1A DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	4.04e-04	237	139	8	SM00389
Domain	-	RXRA PGR NR5A2 NR5A1	4.09e-04	47	139	4	1.10.565.10
Domain	HOMEOBOX_2	HNF1A DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	4.27e-04	239	139	8	PS50071
Domain	Homeobox_dom	HNF1A DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	4.27e-04	239	139	8	IPR001356
Domain	Nucl_hrmn_rcpt_lig-bd	RXRA PGR NR5A2 NR5A1	4.43e-04	48	139	4	IPR000536
Domain	HOLI	RXRA PGR NR5A2 NR5A1	4.43e-04	48	139	4	SM00430
Domain	Hormone_recep	RXRA PGR NR5A2 NR5A1	4.43e-04	48	139	4	PF00104
Domain	SH3_2	SHANK1 MIA3 SH3PXD2B CASKIN1 BAIAP2L2	4.56e-04	86	139	5	PF07653
Domain	SH3_2	SHANK1 MIA3 SH3PXD2B CASKIN1 BAIAP2L2	4.56e-04	86	139	5	IPR011511
Domain	Homeobox_CS	DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	4.90e-04	186	139	7	IPR017970
Domain	NUT	NUTM2A NUTM2B	5.42e-04	5	139	2	IPR024310
Domain	NUT_N	NUTM2A NUTM2B	5.42e-04	5	139	2	IPR024309
Domain	NUT	NUTM2A NUTM2B	5.42e-04	5	139	2	PF12881
Domain	-	RXRA PGR NR5A2 NR5A1	8.55e-04	57	139	4	3.30.50.10
Domain	Znf_NHR/GATA	RXRA PGR NR5A2 NR5A1	9.13e-04	58	139	4	IPR013088
Domain	Laminin_G	COL22A1 CELSR2 NRXN2 CRB2	9.13e-04	58	139	4	IPR001791
Domain	-	HNF1A DBX2 ISL2 GBX1 DMBX1 TLX2 NKX2-4 MIXL1	1.28e-03	283	139	8	1.10.10.60
Pathway	REACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS	RXRA PGR NR5A2 NR5A1	5.19e-05	28	105	4	MM15042
Pathway	REACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS	RXRA PGR NR5A2 NR5A1	6.86e-05	30	105	4	M27323
Pathway	WP_NUCLEAR_RECEPTORS	RXRA PGR NR5A2 NR5A1	1.77e-04	38	105	4	M39657
Pathway	WP_NUCLEAR_RECEPTORS	RXRA PGR NR5A2 NR5A1	1.77e-04	38	105	4	MM15865
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXN1 HNF1A ZNF444 DBX2 SOX17 ISL2 GBX1 HIF3A ZNF385A DMBX1 RXRA PGR TLX2 HIVEP3 FOXP4 KMT2D BCL11B NKX2-4 MIXL1 NR5A2 SKOR1 NR5A1 LYL1 OLIG2 ZNF282	6.43e-14	908	144	25	19274049
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 MIA3 HCN4 PLA2G15 SHISA7 PTK2 KIF7 DLGAP3 SH3PXD2B BCL11B CELSR2 ABI2 CASKIN1 SEC16A STRN4 SYN1 RIMS1 UBASH3B GOLGA3	1.99e-08	963	144	19	28671696
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6B LZTR1 PPRC1 BCAS3 MEX3D KDM6B FAAP100 HDAC7 RYR1 KCNH3 CABLES1 C6orf132 HIVEP3 SH3PXD2B KMT2D CELSR2 ADAMTS7 CASKIN1 SEC16A STRN4	3.38e-08	1105	144	20	35748872
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HNF1A LZTR1 TRIP6 SOX17 ISL2 ZNF385A PRR3 DMBX1 RXRA HIVEP3 LIMK1 KRBA1 NKX2-4 ATXN1 NR5A2 ZNF282	2.70e-07	808	144	16	20412781
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TNK1 ATXN2L RAP1GAP ILK TRIP6 BCAS3 RANBP3 PAK4 ZNRF2 HDAC7 C6orf132 LIMK1 SH3PXD2B ATXN1 AMOT SEC16A	6.25e-07	861	144	16	36931259
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SHANK1 ATXN2L EVL ATN1 VWCE KIF7 DLGAP3 ATXN1 ABI2 SHARPIN CHRD LZTS2 GOLGA3	6.56e-07	560	144	13	21653829
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EVL ZNF444 MIA3 MAN2B2 BCAS3 MACROD1 ZNF385A MAP3K12 JMJD1C RXRA PTK2 TTC19 HIVEP3 FOXP4 SLC41A3 ATXN1 FBXO42 C1orf159 RIMS1 LZTS2 CPNE7	9.28e-07	1489	144	21	28611215
Pubmed	Nuclear receptors in Leydig cell gene expression and function.	RXRA PGR NR5A2 NR5A1	1.95e-06	22	144	4	20375256
Pubmed	Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: involvement of cAMP/PKA signaling.	RXRA PGR LIPE	2.40e-06	7	144	3	24265455
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZNF444 ISL2 DMBX1 RXRA TLX2 BCL11B MIXL1 NR5A2 SKOR1 NR5A1 OLIG2 ZNF282	3.04e-06	544	144	12	28473536
Pubmed	Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.	PTK2 BCL11B TLE4	5.73e-06	9	144	3	28935710
Pubmed	Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated nuclear receptor Ad4BP/SF-1.	RXRA NR5A2 NR5A1	8.17e-06	10	144	3	19692572
Pubmed	PAK4 kinase is essential for embryonic viability and for proper neuronal development.	PAK4 ISL2 OLIG2	8.17e-06	10	144	3	14517283
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CCR10 HCN4 PANX2 RYR1 DLGAP3 CELSR2 CHRD NR5A1 RIMS1	1.01e-05	329	144	9	17474147
Pubmed	Common genetic polymorphisms in moyamoya and atherosclerotic disease in Europeans.	MIA3 LIMK1 ELN	1.12e-05	11	144	3	20694560
Pubmed	Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development.	BCL11B ATXN1 TLE4	1.12e-05	11	144	3	32245946
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	TRIP6 JMJD1C KRBA1 KMT2D ATXN1 SEC16A LZTS2	1.24e-05	184	144	7	32908313
Pubmed	De novo genic mutations among a Chinese autism spectrum disorder cohort.	SHANK1 HIVEP3 RIMS1	1.49e-05	12	144	3	27824329
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	TRIP6 DMBX1 RXRA IKZF4 PGR FOXP4 NR5A2 NR5A1	1.49e-05	263	144	8	20932939
Pubmed	Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function.	SOX17 PGR	1.70e-05	2	144	2	27102016
Pubmed	Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation.	ILK PTK2	1.70e-05	2	144	2	19211680
Pubmed	Inhibition of Integrin-Associated Kinases FAK and ILK on the In Vitro Model of Skin Wound Healing.	ILK PTK2	1.70e-05	2	144	2	38165590
Pubmed	Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.	ILK CHRD	1.70e-05	2	144	2	11704830
Pubmed	A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.	LIMK1 ELN	1.70e-05	2	144	2	16611674
Pubmed	LRH-1/hB1F and HNF1 synergistically up-regulate hepatitis B virus gene transcription and DNA replication.	HNF1A NR5A2	1.70e-05	2	144	2	14728801
Pubmed	A novel isoform of liver receptor homolog-1 is regulated by steroidogenic factor-1 and the specificity protein family in ovarian granulosa cells.	NR5A2 NR5A1	1.70e-05	2	144	2	23471216
Pubmed	Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin.	PAK4 LIMK1	1.70e-05	2	144	2	11413130
Pubmed	Liver receptor homolog-1 and steroidogenic factor-1 have similar actions on rat granulosa cell steroidogenesis.	NR5A2 NR5A1	1.70e-05	2	144	2	17095585
Pubmed	The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells.	KDM6B OLIG2	1.70e-05	2	144	2	35132566
Pubmed	Differentiation of mesenchymal stem cells and embryonic stem cells into steroidogenic cells using steroidogenic factor-1 and liver receptor homolog-1.	NR5A2 NR5A1	1.70e-05	2	144	2	21129436
Pubmed	Liver receptor homolog-1 is essential for pregnancy.	PGR NR5A2	1.70e-05	2	144	2	23817023
Pubmed	Liver receptor homologue-1 and steroidogenic factor-1 expression in cultured granulosa cells from patients with endometriosis: A preliminary study.	NR5A2 NR5A1	1.70e-05	2	144	2	26530052
Pubmed	Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus.	SOX17 PGR	1.70e-05	2	144	2	22638070
Pubmed	A common variant of RIP3 promoter region is associated with poor prognosis in heart failure patients by influencing SOX17 binding.	RIPK3 SOX17	1.70e-05	2	144	2	31148336
Pubmed	Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins.	SHANK1 SHARPIN	1.70e-05	2	144	2	11178875
Pubmed	Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist.	NR5A2 NR5A1	1.70e-05	2	144	2	33335203
Pubmed	The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1.	NR5A2 NR5A1	1.70e-05	2	144	2	15897460
Pubmed	Steroidogenic Factor 1 Regulation of the Hypothalamic-Pituitary-Ovarian Axis of Adult Female Mice.	PGR NR5A1	1.70e-05	2	144	2	35247045
Pubmed	Decreased TCF1 and BCL11B expression predicts poor prognosis for patients with chronic lymphocytic leukemia.	HNF1A BCL11B	1.70e-05	2	144	2	36211334
Pubmed	LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition.	LIMK1 ELN	1.70e-05	2	144	2	8689688
Pubmed	A new case of keratoconus associated with Williams-Beuren syndrome.	LIMK1 ELN	1.70e-05	2	144	2	23167938
Pubmed	Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis.	NR5A2 NR5A1	1.70e-05	2	144	2	23637637
Pubmed	Expression of LRH-1 and SF-1 in the mouse ovary: localization in different cell types correlates with differing function.	NR5A2 NR5A1	1.70e-05	2	144	2	12972182
Pubmed	Transcription of LIPE gene encoding hormone-sensitive lipase/cholesteryl esterase is regulated by SF-1 in human adrenocortical cells: involvement of protein kinase A signal transduction pathway.	LIPE NR5A1	1.70e-05	2	144	2	21081692
Pubmed	Liver receptor homologue-1 expression in ovarian epithelial and granulosa cell tumours.	NR5A2 NR5A1	1.70e-05	2	144	2	23537609
Pubmed	Expression of two inflammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects.	RIPK3 RNF216	1.70e-05	2	144	2	19690434
Pubmed	LRH-1 May Rescue SF-1 Deficiency for Steroidogenesis: An in vitro and in vivo Study.	NR5A2 NR5A1	1.70e-05	2	144	2	25896302
Pubmed	A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency.	NR5A2 NR5A1	1.70e-05	2	144	2	20823062
Pubmed	Cloning and sequence analysis of the human gene encoding steroidogenic factor 1.	NR5A2 NR5A1	1.70e-05	2	144	2	8938589
Pubmed	Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells.	NR5A2 NR5A1	1.70e-05	2	144	2	31058195
Pubmed	The expression profiles of nuclear receptors in the developing and adult kidney.	RXRA NR5A2 NR5A1	2.45e-05	14	144	3	16973757
Pubmed	Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.	RXRA NR5A2 NR5A1	3.05e-05	15	144	3	14701856
Pubmed	Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.	ISL2 FOXP4 OLIG2	3.74e-05	16	144	3	22542185
Pubmed	The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family.	NR5A2 NR5A1	5.09e-05	3	144	2	8668203
Pubmed	Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis.	PGR NR5A1	5.09e-05	3	144	2	27018534
Pubmed	The role of RasGRPs in regulation of lymphocyte proliferation.	FOXN1 RASGRP3	5.09e-05	3	144	2	16530850
Pubmed	Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation.	SOX17 MIXL1	5.09e-05	3	144	2	17151016
Pubmed	Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases.	ILK PTK2	5.09e-05	3	144	2	17213807
Pubmed	p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL.	PAK4 LIPE	5.09e-05	3	144	2	38216738
Pubmed	EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility.	ILK PTK2	5.09e-05	3	144	2	19118217
Pubmed	FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.	PTK2 DLGAP3	5.09e-05	3	144	2	16202977
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	5.09e-05	3	144	2	26542179
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2A NUTM2B	5.09e-05	3	144	2	22456610
Pubmed	Novel human and mouse genes encoding a shank-interacting protein and its upregulation in gastric fundus of W/WV mouse.	SHANK1 SHARPIN	5.09e-05	3	144	2	12753155
Pubmed	Effects of SCA1, MJD, and DPRLA triplet repeat polymorphisms on cognitive phenotypes in a normal population of adolescent twins.	ATN1 ATXN1	5.09e-05	3	144	2	16967484
Pubmed	Prospero-related homeobox protein (Prox1) inhibits hepatitis B virus replication through repressing multiple cis regulatory elements.	HNF1A NR5A2	5.09e-05	3	144	2	19264593
Pubmed	LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1.	NR5A2 NR5A1	5.09e-05	3	144	2	12482977
Pubmed	PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.	FOXN1 PAK4	5.09e-05	3	144	2	31399573
Pubmed	Williams-Beuren syndrome: a challenge for genotype-phenotype correlations.	LIMK1 ELN	5.09e-05	3	144	2	12952863
Pubmed	Polymorphism of trinucleotide repeats in loci DM, DRPLA and SCA1 in East European populations.	ATN1 ATXN1	5.09e-05	3	144	2	11781699
Pubmed	Expression and clinical significance of FAK, ILK, and PTEN in salivary adenoid cystic carcinoma.	ILK PTK2	5.09e-05	3	144	2	23186335
Pubmed	A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF.	PAK4 LIMK1	5.09e-05	3	144	2	18424072
Pubmed	A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.	HNF1A MIA3 CELSR2	5.42e-05	18	144	3	20971364
Pubmed	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.	TRIP6 JMJD1C RXRA	5.42e-05	18	144	3	7776974
Pubmed	Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain.	DBX2 ISL2 OLIG2	5.42e-05	18	144	3	12874134
Pubmed	Additive effect of multiple genetic variants on the risk of coronary artery disease.	HNF1A MIA3 CELSR2	6.42e-05	19	144	3	20738937
Pubmed	m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs.	ISL2 SEMA4C BCL11B	6.42e-05	19	144	3	36039295
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	HNF1A ISL2 ZNF385A HDAC7 MIXL1 TLE4 NR5A2 NR5A1 HDAC10	7.30e-05	424	144	9	21731673
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	ISL2 KDM6B OLIG2	7.53e-05	20	144	3	35177643
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	IKZF4 ZNF469 KRBA1 TTBK1 LZTS2	8.59e-05	107	144	5	11347906
Pubmed	Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.	HNF1A RAP1GAP JMJD1C	8.75e-05	21	144	3	18940312
Pubmed	The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.	KDM6B BCL11B TLE4	8.75e-05	21	144	3	27600842
Pubmed	DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1.	PAK4 LIMK1	1.02e-04	4	144	2	19778628
Pubmed	SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.	SHANK1 SHARPIN	1.02e-04	4	144	2	23897824
Pubmed	Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea.	FOXN1 KMT2D	1.02e-04	4	144	2	16972005
Pubmed	MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.	PAK4 LIMK1	1.02e-04	4	144	2	28440035
Pubmed	Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness.	RXRA ZNF469	1.02e-04	4	144	2	22814818
Pubmed	Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population.	RFX6 FOXP4	1.02e-04	4	144	2	22662242
Pubmed	Integrin-linked kinase: a multi-functional regulator modulating extracellular pressure-stimulated cancer cell adhesion through focal adhesion kinase and AKT.	ILK PTK2	1.02e-04	4	144	2	19633364
Pubmed	Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing.	KIF7 KMT2D	1.02e-04	4	144	2	32738303
Pubmed	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.	NR5A2 NR5A1	1.02e-04	4	144	2	15707893
Pubmed	An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium.	ILK PTK2	1.02e-04	4	144	2	23263281
Pubmed	Is the 31 CAG repeat allele of the spinocerebellar ataxia 1 (SCA1) gene locus non-specifically associated with trinucleotide expansion diseases?	ATN1 ATXN1	1.02e-04	4	144	2	11807410
Pubmed	Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor.	HNF1A GOLGA3	1.02e-04	4	144	2	8639776
Pubmed	KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.	FOXN1 KMT2D	1.02e-04	4	144	2	36525973
Pubmed	Temporal and spatial expression of liver receptor homologue-1 (LRH-1) during embryogenesis suggests a potential role in gonadal development.	NR5A2 NR5A1	1.02e-04	4	144	2	16003771
Pubmed	PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1.	NR5A2 NR5A1	1.02e-04	4	144	2	20133449
Pubmed	The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation.	SOX17 KDM6B	1.02e-04	4	144	2	23584530
Pubmed	RIP1 kinase activity is critical for skin inflammation but not for viral propagation.	RIPK3 SHARPIN	1.02e-04	4	144	2	31985117
Pubmed	Association of THADA, FOXP4, GPRC6A/RFX6 genes and 8q24 risk alleles with prostate cancer in Northern Chinese men.	RFX6 FOXP4	1.02e-04	4	144	2	26537068
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	ZNF385A MAP3K12 HDAC7 IKZF4 KCNH3 KMT2D SLC39A5	3.99e-04	423	144	7	chr12q13
Cytoband	8q24.3	COL22A1 PTK2 TONSL SHARPIN	4.59e-04	113	144	4	8q24.3
GeneFamily	Nuclear hormone receptors	RXRA PGR NR5A2 NR5A1	1.79e-04	49	104	4	71
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SEMA6B ATXN2L ZNF444 ATN1 PPRC1 RANBP3 ARHGAP30 HDAC7 NUTM2E KMT2D HDAC10	2.84e-06	338	144	11	M17094
Coexpression	GSE30083_SP2_VS_SP4_THYMOCYTE_UP	WHRN HIF3A PTK2 HIVEP3 NKX2-4 TONSL ELN HDAC10	1.55e-05	200	144	8	M5034
Coexpression	GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP	RIPK3 ZNF385A HDAC7 RYR1 NKX2-4 SHARPIN IFFO2 LYL1	1.55e-05	200	144	8	M3842
Coexpression	CARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_UP	TMC2 ATN1 GAS2L3 RFX6 ZNF385A HDAC7 PTK2 KIF7 LIMK1 SH3PXD2B KRBA1 MIXL1 CASKIN1 LZTS2 SDK1 INPP5J	3.30e-05	891	144	16	M45033
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD PANX2 KCNH3 DLGAP3 CELSR2 NRXN2 SYN1 CPNE7	1.78e-07	187	144	8	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD PANX2 KCNH3 DLGAP3 CELSR2 NRXN2 SYN1 CPNE7	1.78e-07	187	144	8	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD PANX2 KCNH3 DLGAP3 CELSR2 NRXN2 SYN1 CPNE7	1.78e-07	187	144	8	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD SHISA7 RYR1 KCNH3 DLGAP3 BCL11B TTBK1	1.88e-06	178	144	7	a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD SHISA7 RYR1 KCNH3 DLGAP3 BCL11B TTBK1	1.88e-06	178	144	7	1bddbc083c36657bd6910f7466126ab325e88176
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN2L ATN1 KDM6B IKZF4 FOXP4 CELSR2 IFFO2	2.51e-06	186	144	7	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SEMA6B COL4A6 MUC19 RFX6 JMJD1C RXRA HDAC10	2.51e-06	186	144	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN2L ATN1 KDM6B IKZF4 FOXP4 CELSR2 IFFO2	2.79e-06	189	144	7	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZMYND15 TNK1 COL4A6 CHRD SDK1 BAIAP2L2	4.96e-06	134	144	6	d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZMYND15 TNK1 COL4A6 CHRD SDK1 BAIAP2L2	4.96e-06	134	144	6	459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZMYND15 TNK1 COL4A6 CHRD SDK1 BAIAP2L2	4.96e-06	134	144	6	d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ZMYND15 TNK1 COL4A6 CHRD SDK1 BAIAP2L2	4.96e-06	134	144	6	0be389f416818a22e80098dd809fdf45b14171e8
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))-\|Thalamus / BrainAtlas - Mouse McCarroll V32	MFRP DMBX1 LMAN1L RP1L1 SKOR1	5.83e-06	79	144	5	d4f9297084aea33203dd98d7f6f837b6eb00b6c3
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))--\|Thalamus / BrainAtlas - Mouse McCarroll V32	MFRP DMBX1 LMAN1L RP1L1 SKOR1	5.83e-06	79	144	5	5c37af70dca7e9847f44d7f5969d4b06c32b4ca0
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))\|Thalamus / BrainAtlas - Mouse McCarroll V32	MFRP DMBX1 LMAN1L RP1L1 SKOR1	5.83e-06	79	144	5	75d8cbf8c7a6a4a825143f7d04a604e97bab0fe5
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARTN ZNF385A RYR1 ZNF469 SKOR1 INPP5J	1.32e-05	159	144	6	6115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ARTN ZNF385A RYR1 ZNF469 SKOR1 INPP5J	1.37e-05	160	144	6	a90eb621481fd07a821495db07d1032e109fd386
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL TOGARAM2 MYO1F SYN1 CRB2 CPNE7	2.06e-05	172	144	6	c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCR10 KIF7 KRBA1 RASGRP3 IFFO2 HS3ST6	2.13e-05	173	144	6	62abaaaf48cabd1423f17fb27c33b75ea88867f4
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCR10 KIF7 KRBA1 RASGRP3 IFFO2 HS3ST6	2.13e-05	173	144	6	09cd878c33534bd476d6a4880f5582076189da8c
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	WHRN PPRC1 KIF7 VSIG10L NME4 CPNE7	2.50e-05	178	144	6	b8c301d65c0f37941e8e9414d55e90edb6ecc195
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD SHISA7 RYR1 KCNH3 DLGAP3 BCL11B	2.58e-05	179	144	6	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 FAAP100 CABLES1 TONSL NR5A2 MED26	2.75e-05	181	144	6	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	(09)_Ionocytes-(3)_72hpi\|(09)_Ionocytes / shred by cell type and Timepoint	EVL RANBP3 SH3PXD2B TLE4 NME4	2.93e-05	110	144	5	fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCell	CV-Moderate-4\|CV / Virus stimulation, Condition and Cluster	TRIP6 VWCE RXRA PTK2 KIF7 UBASH3B	3.01e-05	184	144	6	90f5b447064743246b09a6c47bf561efafa15e1f
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SHANK1 PANX2 PGR FOXP4 SYN1 RIMS1	3.20e-05	186	144	6	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Aldh1a1_(SNc/VTA)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RIPK3 C6orf132 SKOR1 SLC39A5	3.25e-05	56	144	4	fedec1be5368a82a75f640e84809e4270dd57c85
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Aldh1a1_(SNc/VTA)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	RIPK3 C6orf132 SKOR1 SLC39A5	3.25e-05	56	144	4	1c101711d20817f65314fcf45a4f99d0934206a8
Drug	16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; PC3; HT_HG-U133A	ZNF444 ATN1 BCAS3 RANBP3 KDM6B HIVEP3 BCL11B CELSR2 LYL1	4.37e-06	198	142	9	6592_DN
Drug	estradiol, USP; Up 200; 0.1uM; PC3; HT_HG-U133A	COL4A6 HNF1A ATN1 HCN4 ARTN LIPE ELN RIMS1 OLIG2	4.37e-06	198	142	9	4432_UP
Drug	Carbarsone [121-59-5]; Down 200; 15.4uM; PC3; HT_HG-U133A	WHRN TNK1 ZNF444 ATN1 KDM6B HDAC7 RXRA MYO1F LYL1	4.75e-06	200	142	9	3991_DN
Drug	Ornidazole [16773-42-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A	WHRN RANBP3 HIF3A HDAC7 RYR1 LIMK1 LIPE ADAMTS7 NR5A2	4.75e-06	200	142	9	2272_UP
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ZNF444 TRIP6 PPRC1 RANBP3 ARTN RXRA SEMA4C ZNF282	8.65e-06	163	142	8	5594_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	TRIP6 PPRC1 ARTN RXRA SEMA4C STRN4 ZNF282 IL27RA	1.28e-05	172	142	8	7179_DN
Drug	NSC613009	PTK2 RYR1 CABLES1 TLX2 LIMK1 ABI2 GOLGA3	1.76e-05	130	142	7	CID000003800
Drug	Rifabutin [72559-06-9]; Down 200; 4.8uM; PC3; HT_HG-U133A	TRIP6 PPRC1 HDAC7 STRN4 LYL1 ZNF282 IL27RA CPNE7	2.00e-05	183	142	8	4527_DN
Drug	troglitazone; Down 200; 10uM; PC3; HT_HG-U133A	WHRN ATXN2L ATN1 ARTN HDAC7 SEMA4C LIMK1 LYL1	2.43e-05	188	142	8	4456_DN
Drug	Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A	ATN1 KDM6B MAP3K12 PLA2G15 RYR1 LIMK1 SLC41A3 GOLGA3	3.28e-05	196	142	8	7015_UP
Drug	Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A	ATXN2L ZNF444 RANBP3 BCL11B SLC41A3 MYO1F STRN4 ZNF282	3.40e-05	197	142	8	3515_DN
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A	WHRN ATXN2L ZNF444 LZTR1 ARTN HDAC7 HIVEP3 INPP5J	3.52e-05	198	142	8	4378_DN
Disease	C-reactive protein measurement, high density lipoprotein cholesterol measurement	HNF1A PLA2G15 JMJD1C CELSR2	2.07e-05	34	141	4	EFO_0004458, EFO_0004612
Disease	intracranial aneurysm (is_implicated_in)	SOX17 COL22A1 KMT2D	2.28e-05	12	141	3	DOID:10941 (is_implicated_in)
Disease	fibrinogen measurement, tissue plasminogen activator measurement	ATXN2L HNF1A JMJD1C H1-8	6.39e-05	45	141	4	EFO_0004623, EFO_0004791
Disease	tyrosine measurement	SEMA6B HNF1A JMJD1C RXRA TTBK1	1.46e-04	104	141	5	EFO_0005058
Disease	Endometrial Stromal Sarcoma	NUTM2A NUTM2B	2.25e-04	5	141	2	C0206630
Disease	inflammatory bowel disease	ATXN2L MUC19 RFX6 HIF3A HDAC7 DLGAP3 BCL11B NR5A2 IFFO2	3.22e-04	449	141	9	EFO_0003767
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	3.36e-04	6	141	2	C0334488
Disease	sphingomyelin measurement	ZMYND15 HNF1A JMJD1C KCNH3 CELSR2 UBASH3B SDK1	3.95e-04	278	141	7	EFO_0010118
Disease	Williams Syndrome	LIMK1 ELN	6.23e-04	8	141	2	C0175702
Disease	cesarean section, anxiety	COL22A1 ATXN1	6.23e-04	8	141	2	EFO_0005230, EFO_0009636
Disease	Microphthalmos	MFRP KMT2D	1.21e-03	11	141	2	C0026010
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	ATXN2L HNF1A JMJD1C	1.31e-03	45	141	3	EFO_0004623, EFO_0004792
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ATXN2L ATXN1	1.45e-03	12	141	2	DOID:1441 (implicated_via_orthology)
Disease	cholesteryl esters to total lipids in small VLDL percentage	JMJD1C CELSR2 SEC16A	1.68e-03	49	141	3	EFO_0022256
Disease	Diverticular Bleeding	ISL2 ELN	1.71e-03	13	141	2	C4505353
Disease	Diverticular Diseases	ISL2 ELN	1.71e-03	13	141	2	C4317009
Disease	corneal topography	RXRA ZNF469 BCL11B ADAMTS7	1.89e-03	109	141	4	EFO_0004345
Disease	Pneumoconiosis	HS3ST6 IL27RA	1.99e-03	14	141	2	C0032273
Disease	Bagassosis	HS3ST6 IL27RA	1.99e-03	14	141	2	C0004681
Disease	Familial thoracic aortic aneurysm and aortic dissection	HCN4 SLC2A10 ELN	2.10e-03	53	141	3	C4707243
Disease	Ischemic stroke, fibrinogen measurement	ATXN2L HNF1A JMJD1C	2.34e-03	55	141	3	EFO_0004623, HP_0002140
Disease	factor VII measurement	HNF1A NR5A1 SDK1	2.34e-03	55	141	3	EFO_0004619
Disease	intelligence, self reported educational attainment	ATXN2L JMJD1C IKZF4 LYL1	2.44e-03	117	141	4	EFO_0004337, EFO_0004784
Disease	4-acetamidobutanoate measurement	PANX2 HDAC10	2.60e-03	16	141	2	EFO_0021003
Disease	cholesterol in IDL measurement	HNF1A JMJD1C CELSR2	2.72e-03	58	141	3	EFO_0021899
Disease	fibrinogen measurement, factor VII measurement	ATXN2L HNF1A JMJD1C	2.72e-03	58	141	3	EFO_0004619, EFO_0004623
Disease	neutrophil percentage of leukocytes	HNF1A DUT RFX6 HDAC7 JMJD1C ATXN1 TLE4 UBASH3B IL27RA	2.73e-03	610	141	9	EFO_0007990
Disease	Moyamoya Disease	SLC2A10 ELN	2.94e-03	17	141	2	C0026654
Disease	total lipids in IDL	HNF1A JMJD1C CELSR2	3.00e-03	60	141	3	EFO_0022161
Disease	angina pectoris	MIA3 CELSR2 ADAMTS7 FAM222A	3.10e-03	125	141	4	EFO_0003913
Disease	free cholesterol in IDL measurement	HNF1A JMJD1C CELSR2	3.14e-03	61	141	3	EFO_0022181
Disease	eosinophil percentage of leukocytes	RFX6 HIF3A KDM6B JMJD1C IKZF4 CABLES1 HIVEP3 SHARPIN OLIG2 ZNF282	3.19e-03	746	141	10	EFO_0007991
Disease	alkaline phosphatase measurement	WHRN HNF1A RAP1GAP TRIP6 JMJD1C HIVEP3 ATRIP CASKIN1 RP1L1 TONSL GBGT1 UBASH3B	3.54e-03	1015	141	12	EFO_0004533
Disease	Tinnitus	BCL11B CHRD SDK1 BAIAP2L2	3.56e-03	130	141	4	HP_0000360
Disease	cognitive function measurement	ATXN2L MACROD1 RFX6 PLA2G15 JMJD1C RXRA PTK2 KCNH3 KMT2D BCL11B ATXN1 FAM222A RNF216 SDK1 CPNE7	3.65e-03	1434	141	15	EFO_0008354
Disease	level of Sphingomyelin (d38:2) in blood serum	HNF1A MYO1F	3.68e-03	19	141	2	OBA_2045179
Disease	DiGeorge syndrome (implicated_via_orthology)	FOXN1 CHRD	3.68e-03	19	141	2	DOID:11198 (implicated_via_orthology)
Disease	age at initiation of smoking	FAM222A SDK1 CPNE7	3.92e-03	66	141	3	EFO_0021784
Disease	venous thromboembolism, fibrinogen measurement	ATXN2L HNF1A JMJD1C	4.09e-03	67	141	3	EFO_0004286, EFO_0004623
Disease	platelet measurement	ZNF444 KDM6B HDAC7 JMJD1C CABLES1 CHRD	4.15e-03	315	141	6	EFO_0005036
Disease	lymphocyte count	BCAS3 DUT MACROD1 HIF3A ARTN HDAC7 JMJD1C LMAN1L ZNF469 BCL11B NRXN2 TLE4 UBASH3B GOLGA3 IL27RA	4.42e-03	1464	141	15	EFO_0004587
Disease	stroke, coronary artery disease	CELSR2 ADAMTS7	4.49e-03	21	141	2	EFO_0000712, EFO_0001645
Disease	serum gamma-glutamyl transferase measurement	HNF1A MACROD1 FAAP100 ZNRF2 JMJD1C SH3PXD2B CELSR2 FBXO42 RP1L1 LZTS2 UBASH3B	4.54e-03	914	141	11	EFO_0004532
Disease	ascending aortic diameter	JMJD1C HIVEP3 LIMK1 ELN	4.64e-03	140	141	4	EFO_0021787

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLHPAPGPIRTAHGP	ZNF385A	366	Q96PM9
GRGLPLPPSNLPSIH	FAM222A	186	Q5U5X8
PATGPGPHRLSIPSL	AMOT	1031	Q4VCS5
LPAGPRPSTPGRAHL	CCR10	146	P46092
SPGLVHLPELPGFPG	COL4A6	701	Q14031
GPGLTPTHLPGVKEP	HTR3E	371	A5X5Y0
FPRHGGLALQPGPPG	ATN1	971	P54259
PHVAPGRAPPPRAGA	ASB16-AS1	136	Q495Z4
RLPLHSTPKDGGPGP	CELSR2	2771	Q9HCU4
HLSRAPGLITPGSPP	ATXN1	226	P54253
GLVPPGSPGPITRHG	BCAS3	691	Q9H6U6
VNHAPVSPRPGLGLP	ARRDC1	286	Q8N5I2
GRGAPHLPPRPSSTL	ADAMTS7	1226	Q9UKP4
GGRPGLSSLPPRGPH	ATXN2L	371	Q8WWM7
PASRHTPPTIGGSLP	ABI2	356	Q9NYB9
PPTLIHGQAPSAGLP	RANBP3	146	Q9H6Z4
ALPAGRHPPVVLVPG	PLA2G15	31	Q8NCC3
PLPSSQPGGLGPALH	RFX6	601	Q8HWS3
PGPESGLLTVPHGPS	KCNH3	856	Q9ULD8
PPSGASHSPLPAGGL	MFRP	96	Q9BY79
SKPNISGPSPHPRGG	FBXO42	271	Q6P3S6
IPRPGPAQGDGHSLP	FBXO42	601	Q6P3S6
PLPGPGSPEVKRAHG	CASKIN1	1251	Q8WXD9
SGGPRPAITLPGSLH	LINC01548	11	A6NM66
RGSGGPGYLLTPPPH	KRBA1	306	A5PL33
TPPPHPDLGAGGLLS	KRBA1	316	A5PL33
SPSPPALHGPGGGLA	NKX2-4	316	Q9H2Z4
VPPGGPSHSSLPVGR	H1-8	36	Q8IZA3
ALPGPARGVPTGPSH	LZTS2	256	Q9BRK4
APGVAAGGARPPLLH	LZTR1	496	Q8N653
GHGLPGAVLPIPGPR	CRB2	936	Q5IJ48
LSSALPGPPLPARGH	SLC2A10	391	O95528
STGSLPLGPAPHTPR	LMAN1L	496	Q9HAT1
PLGPAPHTPRALGIL	LMAN1L	501	Q9HAT1
PVLASPAGHLPGGRT	ARTN	56	Q5T4W7
PGVPTASLLGGHPRL	JMJD1C	801	Q15652
GHRLVPAAPPGPGPR	KDM6B	326	O15054
PSRAHSPGLLGPALG	BAIAP2L2	226	Q6UXY1
GPPIHVPGRPGSVTF	FAM90A27P	381	A6NNH2
PPGKLTRPSPGSPGH	MUC19	1861	Q7Z5P9
RTSATGPILPPGHPS	EVL	156	Q9UI08
GQGPPGPILRLHLPD	IL27RA	496	Q6UWB1
PGSFVPRPHTAPLGG	KIF7	556	Q2M1P5
PRHSPTLPEPGGLRL	MEX3D	511	Q86XN8
GLPPPALSPSKVHGV	HNF1A	306	P20823
PLRPPGLGSASLHGG	FOXP4	421	Q8IVH2
PGPPLGRAAQHGIPR	DUT	41	P33316
PGLAPPHTRAPSPLG	FAAP100	656	Q0VG06
ATASPVPPGGHAGPR	GOLGA3	1466	Q08378
VRPHTSSPGLGKPPG	MED26	226	O95402
PVGFTPRGGLSPPGH	HCN4	1016	Q9Y3Q4
HLVPGGSAPPSPLLT	RIMS1	1231	Q86UR5
PHLPTANPTGPGERG	NRXN2	561	P58401
AKGPRAPHVAGGPPS	PGR	6	P06401
PPGGLHAPRLSLEGA	C6orf132	1111	Q5T0Z8
IGPPPPRSGHLLYTG	GBX1	31	Q14549
SHSPEGRPPPLLPGG	HDAC10	371	Q969S8
TPHLGGPGPGRPSSK	BCL11B	776	Q9C0K0
LPPLIPGGHATVSGP	CABLES1	146	Q8TDN4
PAAVPGVPLGPHRLL	GBGT1	151	Q8N5D6
VGGAPTPRLQPPAPH	DBX2	46	Q6ZNG2
TPVAPGGGLLGPSHS	DMBX1	241	Q8NFW5
SPRSPLTPRHGPGLA	GAS2L3	16	Q86XJ1
SHRGLPPRSLGVPAG	CPNE7	611	Q9UBL6
VGHPQGKGAPRLPPT	DLGAP3	106	O95886
LEGLRPTIPPGISPH	ILK	406	Q13418
GPPGLPGTTSLFTPH	COL22A1	846	Q8NFW1
GLRTAVPPHEPGGPG	MAP3K12	561	Q12852
LVPPRPRPGHLAGAT	MACROD1	21	Q9BQ69
PELLRPPAPGGGHGL	IFFO2	111	Q5TF58
TSPSRPPGGPIITVH	MAN2B2	981	Q9Y2E5
GHRGGSSPPRLPPGV	LYL1	46	P12980
LPPGVPVISLGHSRP	LYL1	56	P12980
GPPPGTGHPPSKRAR	ATRIP	21	Q8WXE1
HPTLGPRGPILGSPH	HDAC7	271	Q8WUI4
GSHAPLLTVPGLGPL	HDAC7	316	Q8WUI4
SGTPGRPHPGAPRVA	C1orf159	131	Q96HA4
LHPSRPGGVPGAIPG	ELN	21	P15502
NGTRSPPRPSPGGLH	SDK1	2081	Q7Z5N4
PSLHPSLGPGIGSPG	RXRA	31	P19793
GLPGVGVTTSLRPPH	RYR1	1761	P21817
PPLSLGLPGHGAPQT	PPRC1	1036	Q5VV67
GSGPEPHSPGGIRLP	IKZF4	141	Q9H2S9
VHRPGAPGLPLASGP	HS3ST6	71	Q96QI5
PPLAHTGPGPVLVRL	LIPE	591	Q05469
AGLPSGGPFHVRSPP	PANX2	581	Q96RD6
TRARGAPSPGVLGPH	PAK4	251	O96013
ALQHRPSPASGPGPG	ARHGAP30	451	Q7Z6I6
RSPGPLPGARGLHLP	ISL2	156	Q96A47
HGPLLVTAGAPPGGP	NUTM2A	161	Q8IVF1
HGPLLVTAGAPPGGP	NUTM2B	161	A6NNL0
TTPAPGPAHGPLLVT	NUTM2D	81	Q5VT03
GPAHGPLLVTAGAPP	NUTM2D	86	Q5VT03
HGPLLVTAGAPPGGP	NUTM2E	161	B1AL46
IGAGLPDRHGSPIPA	NR5A2	21	O00482
PHLPPAPGQPRGASR	METTL24	56	Q5JXM2
QHLSGLGPPAGSPLP	SYN1	491	P17600
PPHPQRGLGLATGAS	SKOR1	341	P84550
HPRLGPEPAGPSIPG	SOX17	271	Q9H6I2
PPSLHGPEPKGLAAG	NR5A1	141	Q13285
ALPGSRNLVHGPPAP	PSD	166	A5PKW4
LPGHAPFRPLGSLGP	MIA3	1836	Q5JRA6
DLPGSIPGPHELRPG	TOGARAM2	196	Q6ZUX3
GPRAPGPSLLVRHGS	NME4	16	O00746
PPRPGAPGHLGSLAS	PTK2	876	Q05397
GSGPIRPLAPPAGLS	FOXN1	406	O15353
GHGSLPGSPSLPPAQ	RASGRP3	556	Q8IV61
IPHPGSLEPPLGRGA	HIF3A	226	Q9Y2N7
PGDPKSALHRGPPGS	PRR3	51	P79522
SALHRGPPGSRGPLI	PRR3	56	P79522
PGPSRSPHPDAGKLG	RAP1GAP	626	P47736
PPPGGPGTLSLHFLN	SHARPIN	91	Q9H0F6
HSNLLLGPGGPPTPL	SHISA7	451	A6NL88
KPGELGLPHPLSTGG	SLC41A3	16	Q96GZ6
SGLPSVGSIRPPHGL	OLIG2	246	Q13516
GISGPSSPQPAHPLG	RNF216	226	Q9NWF9
GRSISPPSGLPQPHG	WHRN	241	Q9P202
PPSGLPQPHGGALRQ	WHRN	246	Q9P202
PGQPLPSPTRLHLGG	SEMA4C	766	Q9C0C4
PHLPRGPAPSGLDLL	SLC39A5	126	Q6ZMH5
HRLPPTAPGVGPLLL	SHANK1	1446	Q9Y566
EGGPKRTHPTVPGIP	ARNTL	471	O00327
TVTAHLLGPPGTPGP	CHRD	581	Q9H2X0
GPSEPGTHSPGLLSP	INPP5J	311	Q15735
RLHAAPGGDGSPILP	PRSS53	446	Q2L4Q9
VPGPVHLRGRSPTPA	SWI5	51	Q1ZZU3
QVPPSRVAPHGRGPG	TTC19	41	Q6DKK2
TGSLRRPLGPHAPPA	SEMA6B	826	Q9H3T3
PGGPRLVIGSLPAHL	ZNRF2	136	Q8NHG8
RAIPRGTPGPPPAHG	TRIP6	21	Q15654
RDTHPGSPGSPGPAL	ZNF444	226	Q8N0Y2
GRPSEGLGPSPHLVP	TTBK1	376	Q5TCY1
RAPHAGGALLPPPSP	MIXL1	21	Q9H2W2
SPGLGRPPAPTHVGA	SEC16A	406	O15027
PSGKGRGLQHPPPVG	RIPK3	481	Q9Y572
PSSPGLGRVAPRGHP	RP1L1	651	Q8IWN7
GHGLPVPLTPHPSGL	TLE4	141	Q04727
KPGPGSPSHPGALDL	SH3PXD2B	286	A1X283
LGPGPPRGHSKALAP	TONSL	806	Q96HA7
RPGPSGSFVAPGLHP	HIVEP3	126	Q5T1R4
SAPSPPGLHVDPGRG	HIVEP3	2006	Q5T1R4
RPGAHPTLLPGPTAA	HIVEP3	2206	Q5T1R4
AGRPALSPGHSPPSG	VWCE	291	Q96DN2
KDGHQRSPGPPGLPS	ZNF469	761	Q96JG9
GGLPATRPVHRGTPA	TNK1	446	Q13470
PTAGPEPLSLPGILH	STRN4	56	Q9NRL3
DPPILPLTHGPTGGF	UBASH3B	626	Q8TF42
PAGSRLLLPAVGPGH	VSIG10L	451	Q86VR7
PASGHLPISRPPGIG	TMC2	866	Q8TDI7
LPISRPPGIGPDSGH	TMC2	871	Q8TDI7
IPGPGFSRHPRGNTP	ZMYND15	411	Q9H091
VHSGGPGPGAPRQLP	ZNF282	651	Q9UDV7
GPGGVIRVPAHRPLP	TLX2	76	O43763
PGVALPGSPPRSHLL	nan	76	Q8N9W7
PGSPPRSHLLPGTQI	nan	81	Q8N9W7
PGVALPGSPPRSHLL	nan	76	A6NDX4
PGSPPRSHLLPGTQI	nan	81	A6NDX4
GATGGPPAHLLTPSP	KMT2D	3186	O14686
RGLSVSIDPPHGPPG	LIMK1	176	P53667
GTHRPPRGPPSTSLG	MYO1F	976	O00160