Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphospholipid binding

ARHGAP32 MYO1E AGAP11 ATG2A C2CD2L HAVCR1 DENND1B RASAL1 ARAP2 NPM1 WIPI1 APOB SYT16 RASGRP1 APPL1 UNC13C EXOC1 WDFY3

3.91e-0554822018GO:0005543
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

GLUD1 GLUD2

1.21e-0422202GO:0016639
GeneOntologyMolecularFunctionglutamate dehydrogenase [NAD(P)+] activity

GLUD1 GLUD2

1.21e-0422202GO:0004353
GeneOntologyMolecularFunctionglutamate dehydrogenase (NAD+) activity

GLUD1 GLUD2

1.21e-0422202GO:0004352
GeneOntologyMolecularFunctionglutamate dehydrogenase (NADP+) activity

GLUD1 GLUD2

1.21e-0422202GO:0004354
DomainAnk_2

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

3.40e-0821521715PF12796
DomainAnk

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

7.39e-0822821715PF00023
Domain-

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

2.21e-07248217151.25.40.20
DomainANK

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

2.58e-0725121715SM00248
DomainANK_REPEAT

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

2.86e-0725321715PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

3.01e-0725421715IPR020683
DomainANK_REP_REGION

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

3.01e-0725421715PS50297
DomainAnkyrin_rpt

ANKRD37 TRPC6 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

4.47e-0726221715IPR002110
DomainWD40

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 NUP214 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.60e-0526821713SM00320
DomainWD40_repeat

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 NUP214 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.87e-0527221713IPR001680
DomainQuinoprotein_ADH-like_supfam

PCDH19 WDR90 ERN2 EML3 WDR87 CFAP57

3.34e-05532176IPR011047
Domain-

PLXNB2 BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 NUP214 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

3.70e-05333217142.130.10.10
DomainWD40/YVTN_repeat-like_dom

PLXNB2 BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 NUP214 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

3.95e-0533521714IPR015943
DomainWD40

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

5.31e-0525921712PF00400
DomainWD_REPEATS_1

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.04e-0427821712PS00678
DomainWD_REPEATS_2

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.08e-0427921712PS50082
DomainWD_REPEATS_REGION

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.08e-0427921712PS50294
DomainELFV_dehydrog_N

GLUD1 GLUD2

1.34e-0422172PF02812
DomainGlu/Leu/Phe/Val_DH_C

GLUD1 GLUD2

1.34e-0422172IPR006096
DomainGlu/Leu/Phe/Val_DH_dimer_dom

GLUD1 GLUD2

1.34e-0422172IPR006097
DomainGlu/Leu/Phe/Val_DH

GLUD1 GLUD2

1.34e-0422172IPR006095
DomainELFV_dehydrog

GLUD1 GLUD2

1.34e-0422172PF00208
DomainNAD_bind_Glu_DH

GLUD1 GLUD2

1.34e-0422172IPR033922
DomainGLFV_DEHYDROGENASE

GLUD1 GLUD2

1.34e-0422172PS00074
DomainEcm29/Gcn1

GCN1 ECPAS

1.34e-0422172IPR026827
DomainELFV_dehydrog

GLUD1 GLUD2

1.34e-0422172SM00839
DomainGlu/Leu/Phe/Val_DH_AS

GLUD1 GLUD2

1.34e-0422172IPR033524
DomainARM-type_fold

PDS5B USP34 CTIF PIK3R4 PLAA TAF6 GCN1 DOCK9 APOB ECPAS RIF1 UPF2 WDFY3

1.76e-0433921713IPR016024
DomainWD40_repeat_dom

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.93e-0429721712IPR017986
DomainRho_GTPase_activation_prot

ARHGAP32 PLXNB2 IQGAP3 ARHGAP21 RASAL1 ARAP2

5.63e-04882176IPR008936
Domain-

PLXNB2 IQGAP3 RASAL1

7.75e-041621731.10.506.10
DomainMyosin_head_motor_dom

MYH3 MYH7 MYO1A MYO1E

9.60e-04382174IPR001609
DomainMYOSIN_MOTOR

MYH3 MYH7 MYO1A MYO1E

9.60e-04382174PS51456
DomainMyosin_head

MYH3 MYH7 MYO1A MYO1E

9.60e-04382174PF00063
DomainMYSc

MYH3 MYH7 MYO1A MYO1E

9.60e-04382174SM00242
DomainRasGAP_dom

PLXNB2 IQGAP3 RASAL1

1.11e-03182173IPR001936
DomainLaminin_domII

LAMA1 LAMA5

1.31e-0352172IPR010307
DomainAutophagy-rel_C

VPS13C ATG2A

1.31e-0352172IPR015412
DomainATG_C

VPS13C ATG2A

1.31e-0352172PF09333
DomainLaminin_aI

LAMA1 LAMA5

1.31e-0352172IPR009254
DomainLaminin_I

LAMA1 LAMA5

1.31e-0352172PF06008
DomainLaminin_II

LAMA1 LAMA5

1.31e-0352172PF06009
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 ERC1 MCC HLCS LGR4 ABCA8 BRWD3 C2CD2L CEP170 ATXN7L3 EHMT2 FAM120C PCDH19 TAF6 GNL3 ARAP2 NPM1 WWP1 PRSS56 L1TD1 KIAA1671 YEATS2 INTS6 POLR1E BRD7 EHMT1 TANC1 SIGLEC1 WDFY3 PDZRN3 RHOT1

8.79e-1211162243131753913
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH3 MYH7 HIVEP1 SPART NEB MAP3K5 CEP170 STRADB EHMT2 COL14A1 ARHGAP21 GNL3 AKAP6 COL6A3 WWP1 DOCK9 UPF2 PDE4DIP APPL1 EXOC1

1.02e-104972242023414517
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

USP34 VPS13C MAML1 MCC HLCS MPDZ C2CD2L CEP170 NUDT12 KANK1 ASB6 SECISBP2 PRR14L POC5 GNL3 MIA3 ICA1 NUP214 YEATS2 TANC1 CDK11B PLCH1 PDZRN3

5.13e-107332242334672954
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 MYO1E ANKRD37 MAML1 ATG2A PLXNB2 MAP3K5 C2CD2L ZBED4 CASKIN1 WDR90 HERC1 GCN1 IQGAP3 ARHGAP21 DYNC1H1 RASAL1 WWP1 DOCK9 LAMA5 NUP214 EML3 EHMT1 TANC1 WDFY3 MFSD5 SMAD7 HR

7.72e-1011052242835748872
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ARHGAP32 ERC1 RTN3 GPRIN1 C2CD2L CEP170 PLAA FAM120C CASKIN1 GLUD1 GLUD2 GCN1 RASAL1 NPM1 MIA3 ASRGL1 ANK3 DOCK9 TMEM43 WDR47 RAB3GAP1 PDE4DIP CCT8 APPL1 EXOC1 PEAK1 HDLBP

6.52e-0911392242736417873
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ARHGAP32 MYO1E ERC1 RTN3 NCAM2 PIK3R4 CEP170 FAM120C CASKIN1 GLUD1 GLUD2 DMD ARHGAP21 DYNC1H1 RASAL1 NPM1 ASRGL1 ANK3 WDR47 MLXIPL UPF2 PDE4DIP CCT8 EXOC1 TANC1 PEAK1 PLCH1 PCDH1 RHOT1 HDLBP

1.44e-0814312243037142655
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP32 ERC1 MCC MPDZ ARMCX4 MAP3K5 CEP170 EHMT2 FAM120C CASKIN1 ARHGAP21 DYNC1H1 RASAL1 NPM1 DIP2B MIA3 ANK3 WDR47 PDE4DIP BRD7 EHMT1 CCT8 APPL1 WDFY3

1.88e-089632242428671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PDS5B ERC1 C2CD2L KANK1 ZBED4 PCDH19 ARHGAP21 DYNC1H1 ARAP2 DOCK9 NUP214 SLC39A10 WDR47 YEATS2 PDE4DIP

7.56e-084072241512693553
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP34 VPS13C MAML1 LGR4 GPRIN1 EHMT2 GCN1 ARHGAP21 DYNC1H1 ARAP2 NPM1 ANK3 APOB SLC39A10 KIAA1671 RIF1 ZBED6 EHMT1 CCT8 PEAK1

1.84e-077772242035844135
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ARHGAP32 ERC1 HLCS SPART MPDZ GPRIN1 RCC2 CEP170 GCN1 ARHGAP21 DYNC1H1 NPM1 ANK3 NUP214 ECPAS CCT8 PEAK1 PLCH1 HDLBP

2.01e-077082241939231216
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DDX19B ARHGAP32 CDR2 HIVEP1 ERC1 MPDZ PIK3R4 CEP170 FSIP2 DENND1B ARHGAP21 ARAP2 DIP2B NELFCD FAM117B KIAA1671 MLXIPL TANC1 PEAK1 PLCH1 DOP1A

2.18e-078612242136931259
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 ERC1 C2CD2L GCN1 AKAP6 PRUNE2 DOCK9 SETBP1 EHMT1 APPL1 WDFY3

2.71e-072252241112168954
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIVEP1 SPART MTMR10 KANK1 SECISBP2 HERC1 DYNC1H1 ANK3 NELFCD WWP1 L1TD1 LAMA5 HBP1 PDE4DIP PCDH1 SMAD7 HDLBP

3.46e-075912241715231748
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 VPS13C MAML1 SPART AGAP11 ATG2A RCC2 INTS2 CASKIN1 WDR90 OXSR1 AKAP6 LAMA5 ECPAS SETBP1 EHMT1

4.00e-075292241614621295
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 VPS13C RTN3 NCAM2 CTIF BRWD3 CEP170 DENND1B INTS2 FAM120C DHRSX OXSR1 GNL3 PRUNE2 DIP2B MIA3 ANK3 WWP1 FAM117B ECPAS KIAA1671 YEATS2 INTS6 SETBP1 EHMT1 TANC1 PCDH1 DOP1A

4.17e-0714892242828611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MAML1 MPDZ RCC2 C2CD2L ATXN7L3 INTS2 EHMT2 FAM120C RBM15B TAF6 IQGAP3 GNL3 EEFSEC LAMA5 ATAD2 NGDN PWP1 KIAA1671 RIF1 INTS6 GTF2H3 POLR1E ZBED6 BRD7 EHMT1 CCT8 TANC1 HDLBP

4.64e-0714972242831527615
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

NAB1 SPART ADAR RCC2 SALL1 GCN1 DYNC1H1 NPM1 NUP214 YEATS2 EHMT1 CCT8 HDLBP

6.51e-073572241337059091
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 HIVEP1 ERC1 SALL1 EHMT2 GCN1 ARHGAP21 NELFCD NUP214 ECPAS KIAA1671 YEATS2 ZKSCAN3 CCT8

6.53e-074182241434709266
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ARHGAP32 ERC1 GPRIN1 NFKBIE GCN1 ARHGAP21 ANK3 DOCK9 NUP214 NGDN KIAA1671 CCT8 TANC1 PEAK1 PCDH1 HDLBP

9.48e-075652241625468996
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

ARHGAP32 GPRIN1 PLXNB2 MTMR10 C2CD2L DMD DIP2B ANK3 DOCK9 SLC39A10 APPL1 PEAK1 PCDH1

1.20e-063772241338117590
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MYO1E ERC1 SPART ADAR CEP170 FAM120C SECISBP2 OXSR1 GCN1 EEFSEC NGDN GTF2H3 UPF2 EHMT1 CCT8 EXOC1 NNT HDLBP

1.27e-067242241836232890
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PDS5B HIVEP1 VPS13C RTN3 ADAR RCC2 PIK3R4 GLUD1 RBM15B GCN1 IQGAP3 DYNC1H1 GNL3 NPM1 APOB NUP214 TMEM43 ECPAS ATAD2 PWP1 RIF1 EHMT1 CCT8 PEAK1 NNT HDLBP

1.94e-0614252242630948266
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DDX19B ARHGAP32 MPDZ NCAM2 ADAR CEP170 GLUD1 VAV3 NKTR DMD GCN1 ARHGAP21 ARAP2 DOCK9 NUP214 ECPAS KIAA1671 RIF1 APPL1 PEAK1

2.34e-069162242032203420
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

PDS5B ADAR RCC2 PIK3R4 CEP170 RBM15B GCN1 IQGAP3 GNL3 NPM1 EEFSEC TICRR XRCC4 NGDN PWP1 RIF1 UPF2 POLR1E

2.45e-067592241835915203
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ERC1 HLCS SPART GPRIN1 ADAR RCC2 CEP170 GLUD1 PRR14L TAF6 GCN1 ARHGAP21 GNL3 NPM1 NUP214 KIAA1671 YEATS2 RIF1 CCT8 HDLBP

3.13e-069342242033916271
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

ARHGAP32 ERC1 VPS13C MAML1 HLCS CTIF ATG2A NFKBIE POC5 ARHGAP21 DYNC1H1 GNL3 CCHCR1 MIA3 ECPAS KIAA1671 CCT8 TANC1 PDZRN3

3.18e-068532241928718761
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

LAMA1 NEB ADAR RCC2 FAM120C DMD HERC1 GNL3 PWP1 PLCH1

3.20e-062342241036243803
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ERC1 MPDZ GPRIN1 ADAR CEP170 NFKBIE TAF6 GCN1 DYNC1H1 ANK3 KIAA1671 YEATS2 CCT8 PEAK1 HDLBP

3.23e-065492241538280479
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGAP32 MCC ATG2A SALL1 TONSL WDR90 OXSR1 DYNC1H1 PRUNE2 ANK3 NUP214 KIAA1671 SETBP1

5.03e-064302241335044719
Pubmed

Developmental regulation of biglycan expression in muscle and tendon.

MYH3 DMD COL6A3

5.20e-066224316810681
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

USP34 ERC1 MCC NEB GLUD1 OXSR1 GCN1 GNL3 PDE4DIP CCT8 CDK11B WDFY3 RHOT1

5.29e-064322241323455922
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MPDZ RCC2 PIK3R4 TONSL IQGAP3 ARHGAP21 EEFSEC DIP2B MIA3 PWP1 UPF2 PAM TANC1 PLCH1 RHOT1 HR

5.68e-066502241638777146
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

DDX19B MYH7 ERC1 VPS13C NEB ADAR NUP214 PDE4DIP

6.91e-06152224834299191
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BDP1 USP34 HIVEP1 ERC1 MAML1 SPART RTN3 SALL1 TONSL SECISBP2 KIAA1671 YEATS2 TANC1 CDK11B HDLBP

7.34e-065882241538580884
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

USP34 LGR4 HAVCR1 PPARGC1A PLAA INTS2 HERC1 ARHGAP21 AKAP6 CCHCR1 TICRR MIA3 ANK3 WWP1 DOCK9 ICA1 AKNAD1 SALL4 APOB SLC39A10 PEAK1

8.19e-0610842242111544199
Pubmed

Global/temporal gene expression in diaphragm and hindlimb muscles of dystrophin-deficient (mdx) mice.

NEB DMD PDE4DIP

9.05e-067224312176734
Pubmed

Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.

EHMT2 RIF1 EHMT1

9.05e-067224324735877
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

MYO1E ERC1 SPART CEP170 PLAA INTS2 GCN1 NENF CCHCR1 NUP214 TMEM43 SLC39A10 ECPAS NGDN PDE4DIP NNT HDLBP

9.10e-067542241733060197
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

DDX19B PDS5B MYH7 ERC1 MCC PIK3R4 TONSL OXSR1 HERC1 GCN1 DYNC1H1 GNL3 NPM1 NELFCD ICA1 XRCC4 ECPAS EML3 DERA RASGRP1 POLR1E CDK11B HDLBP

1.06e-0512842242317353931
Pubmed

A human MAP kinase interactome.

ARHGAP32 HIVEP1 NEB MAP3K5 VAV3 NKTR DMD ZNF418 GCN1 ANK3 NUP214 RIF1 HDLBP

1.84e-054862241320936779
Pubmed

Interaction network of human early embryonic transcription factors.

HIVEP1 NAB1 MAML1 SALL1 EHMT2 GLUD1 NUP214 KIAA1671 ASXL3 BRD7 EHMT1

1.95e-053512241138297188
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

USP34 ERC1 VPS13C ARHGAP21 ANK3 DOCK9 DOP1A

2.04e-05128224730995482
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGAP32 CTIF ABCA8 CEP170 PRUNE2 SLC7A14 RAB3GAP1 CCT8 APPL1 PEAK1 PLCH1 PDZRN3 DOP1A

2.14e-054932241315368895
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

ERC1 VPS13C SPART C2CD2L CEP170 PRR14L GCN1 MIA3 WIPI1 NUP214 RAB3GAP1 CCT8 TANC1 HDLBP

2.17e-055682241437774976
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ARHGAP32 MYO1E MTMR10 ARHGAP21 ARAP2 DIP2B WWP1 DOCK9 APOB SLC39A10 ATAD2 TANC1 PEAK1 PCDH1

2.21e-055692241430639242
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

RCC2 CEP170 DMD GCN1 ARHGAP21 DYNC1H1 GNL3 NPM1 ECPAS NGDN MLXIPL GTF2H3 POLR1E CCT8 EXOC1 TANC1 HDLBP

2.23e-058092241732129710
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PDS5B CENPC ADAR PIK3R4 PLAA PRR14L GCN1 DYNC1H1 GNL3 NPM1 NUP214 ATAD2 WDR47 NGDN RIF1 RAB3GAP1 UPF2 POLR1E CCT8 EXOC1 TANC1 WDFY3 HDLBP

2.42e-0513532242329467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B USP34 RCC2 CEP170 GCN1 DYNC1H1 GNL3 NPM1 NUP214 ECPAS ATAD2 PWP1 RIF1 NNT HDLBP

2.50e-056532241522586326
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

HIVEP1 MYO1E ERC1 CEP170 RBM15B NPM1 ANKRD35 ANK3 NGDN ASXL3 CHEK2

2.52e-053612241126167880
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH3 VPS13C LAMA1 GPRIN1 NUDT12 ZBED4 FAM120C PKHD1 DYNC1H1 TICRR ICA1 ECPAS KIAA1671 TLR3 CCT8 CFAP57

2.61e-057362241629676528
Pubmed

Genomic analysis of mouse retinal development.

CDR2 ADAR PIK3R4 ATXN7L3 TONSL SECISBP2 WIPI1 HBP1 PWP1 RAB3GAP1 ANKRD33 PDE4DIP ZKSCAN3 BRD7 WDFY3 PLCH1 SAMD14 PIK3R5 TPH1

3.16e-0510062241915226823
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

GPRIN1 PLXNB2 PCDH19 ANK3 RAB3GAP1 PEAK1

3.39e-0594224632062451
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

PDS5B USP34 OXSR1 PWP1 APPL1 CDK11B PLCH1 SAMD14 PCDH1

3.41e-05246224915345747
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

BDP1 MYH3 ELP5 NEB PIK3R4 CEP170 KANK1 SALL1 DENND1B SECISBP2 AKAP6 NPM1 ASRGL1 ANK3 E2F5 ATAD2 ZNF419 PDE4DIP CCT8 SERPIND1 SMAD7 HDLBP

3.61e-0512932242215342556
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

DDX19B VPS13C RTN3 ARMCX4 PLXNB2 C2CD2L SPTBN5 EHMT2 GLUD1 SECISBP2 HERC1 MCUB GNL3 DIP2B MIA3 NELFCD GFM2 KIAA1671 RAB3GAP1 UPF2 BRD7 TANC1 NNT RHOT1

4.02e-0514962242432877691
Pubmed

ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function.

ATXN7L3 SMAD7

4.13e-052224233186807
Pubmed

Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.

GLUD1 GLUD2

4.13e-052224234173171
Pubmed

Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.

GLUD1 GLUD2

4.13e-052224228621566
Pubmed

Rescue of dystrophic skeletal muscle by PGC-1α involves restored expression of dystrophin-associated protein complex components and satellite cell signaling.

PPARGC1A DMD

4.13e-052224223594613
Pubmed

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.

SALL1 SALL4

4.13e-052224219476507
Pubmed

GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.

GLUD1 GLUD2

4.13e-052224232078638
Pubmed

Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer.

EHMT2 EHMT1

4.13e-052224233283949
Pubmed

Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.

GLUD1 GLUD2

4.13e-052224223595828
Pubmed

PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.

PPARGC1A DMD

4.13e-052224217403779
Pubmed

The laminin response in inflammatory bowel disease: protection or malignancy?

LAMA1 LAMA5

4.13e-052224225347196
Pubmed

Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.

GLUD1 GLUD2

4.13e-052224221621574
Pubmed

Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.

GLUD1 GLUD2

4.13e-052224228911206
Pubmed

Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes.

UGT3A1 UGT3A2

4.13e-052224222621930
Pubmed

Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.

GLUD1 GLUD2

4.13e-052224222875990
Pubmed

The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner.

DDX19B NUP214

4.13e-052224219219046
Pubmed

Histone Methyltransferases G9a/Ehmt2 and GLP/Ehmt1 Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma.

EHMT2 EHMT1

4.13e-052224237894922
Pubmed

Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.

GLUD1 GLUD2

4.13e-052224215578726
Pubmed

Low-Level Photobiomodulation Therapy Modulates H2O2 Production, TRPC-6, and PGC-1α Levels in the Dystrophic Muscle.

TRPC6 PPARGC1A

4.13e-052224237527194
Pubmed

Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.

GLUD1 GLUD2

4.13e-052224215044002
Pubmed

Peroxisome proliferator-activated receptor γ coactivator1- gene α transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdx mouse skeletal muscle.

PPARGC1A DMD

4.13e-052224222907054
Pubmed

Induction of excitatory and inhibitory presynaptic differentiation by GluD1.

GLUD1 GLUD2

4.13e-052224222138648
Pubmed

[Correlation between ultrastructural changes of glomerular basement membrane and abnormal distribution of laminins in patients with Alport's syndrome].

LAMA1 LAMA5

4.13e-052224220019771
Pubmed

Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability.

EHMT2 EHMT1

4.13e-052224225637356
Pubmed

Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.

GLUD1 GLUD2

4.13e-052224234220417
Pubmed

Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.

DDX19B NUP214

4.13e-052224210428971
Pubmed

Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.

GLUD1 GLUD2

4.13e-052224226241911
Pubmed

G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells.

EHMT2 EHMT1

4.13e-052224227052169
Pubmed

The histone H3 lysine 9 methyltransferase G9a/GLP complex activity is required for long-term consolidation of spatial memory in mice.

EHMT2 EHMT1

4.13e-052224233609736
Pubmed

Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells.

MYO1A MYO1E

4.13e-05222429858156
Pubmed

Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.

GLUD1 GLUD2

4.13e-052224221446915
Pubmed

GluD1 binds GABA and controls inhibitory plasticity.

GLUD1 GLUD2

4.13e-052224238060673
Pubmed

Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.

GLUD1 GLUD2

4.13e-052224224593767
Pubmed

Potentiation of neuronal activity by tonic GluD1 current in brain slices.

GLUD1 GLUD2

4.13e-052224237154294
Pubmed

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.

GLUD1 GLUD2

4.13e-052224222924626
Pubmed

Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities.

EHMT2 EHMT1

4.13e-052224234619147
Pubmed

Functional Crosstalk Between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2.

EHMT2 EHMT1

4.13e-052224225365549
Pubmed

A novel protein domain induces high affinity selenocysteine insertion sequence binding and elongation factor recruitment.

SECISBP2 EEFSEC

4.13e-052224218948268
Pubmed

Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.

GLUD1 GLUD2

4.13e-052224211032875
Pubmed

Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.

GLUD1 GLUD2

4.13e-052224229943084
Pubmed

Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.

GLUD1 GLUD2

4.13e-052224231898404
Pubmed

Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.

GLUD1 GLUD2

4.13e-052224215378063
Pubmed

Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.

GLUD1 GLUD2

4.13e-052224227422263
Pubmed

Transgenic expression of Laminin α1 chain does not prevent muscle disease in the mdx mouse model for Duchenne muscular dystrophy.

LAMA1 DMD

4.13e-052224221435454
Pubmed

Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.

GLUD1 GLUD2

4.13e-052224215750346
Pubmed

Evidence of a sex-dependent restrictive epigenome in schizophrenia.

EHMT2 EHMT1

4.13e-052224225935252
InteractionYWHAH interactions

ARHGAP32 CDR2 HIVEP1 MYO1E ERC1 MPDZ NCAM2 MTMR10 MAP3K5 PIK3R4 CEP170 KANK1 DENND1B RBM15B NKTR HERC1 ARHGAP21 ARAP2 DIP2B TICRR RPS6KA4 NELFCD DOCK9 FAM117B EML3 KIAA1671 MLXIPL APPL1 TANC1 PEAK1 PLCH1 DOP1A TPH1

1.05e-07110221833int:YWHAH
InteractionYWHAG interactions

DDX19B ARHGAP32 CDR2 HIVEP1 ERC1 MCC LGR4 MPDZ RTN3 NCAM2 MAP3K5 C2CD2L PIK3R4 CEP170 KANK1 DENND1B RBM15B NKTR ARHGAP21 DYNC1H1 ARAP2 TICRR RPS6KA4 NELFCD DOCK9 FAM117B EML3 KIAA1671 MLXIPL APPL1 TANC1 CDK11B PEAK1 PLCH1 DOP1A

2.01e-07124821835int:YWHAG
InteractionYWHAZ interactions

BDP1 ARHGAP32 CDR2 HIVEP1 ERC1 MCC LGR4 NCAM2 NEB MTMR10 MAP3K5 CEP170 FSIP2 KANK1 DENND1B PRR14L ARHGAP21 DYNC1H1 ARAP2 NPM1 TICRR NELFCD DOCK9 FAM117B EML3 KIAA1671 MLXIPL ASXL3 APPL1 TANC1 CDK11B WDFY3 PEAK1 PLCH1 TPH1

7.37e-07131921835int:YWHAZ
InteractionUBXN6 interactions

USP34 MAP3K5 PLAA EHMT2 ASB6 TONSL PRR14L OXSR1 HERC1 IQGAP3 RPS6KA4 CHEK2 CCT8 CDK11B HDLBP

2.75e-0632521815int:UBXN6
InteractionKCNA3 interactions

ARHGAP32 ERC1 LAMA1 HLCS SPART MPDZ GPRIN1 RCC2 CEP170 PKHD1 GCN1 IQGAP3 ARHGAP21 DYNC1H1 NPM1 ANK3 AKNAD1 NUP214 ECPAS YEATS2 TLR3 CCT8 PEAK1 PLCH1 DOP1A HDLBP

2.87e-0687121826int:KCNA3
InteractionTOP3B interactions

DDX19B USP34 MYO1E ANKRD37 MAML1 CTIF ATG2A PLXNB2 MAP3K5 C2CD2L ZBED4 FAM120C CASKIN1 SECISBP2 WDR90 HERC1 GCN1 IQGAP3 ARHGAP21 DYNC1H1 RASAL1 WWP1 DOCK9 LAMA5 APOB NUP214 EML3 UPF2 EHMT1 TANC1 WDFY3 MFSD5 SMAD7 HDLBP HR

8.34e-06147021835int:TOP3B
InteractionYWHAB interactions

ARHGAP32 CDR2 HIVEP1 ERC1 MCC RTN3 NCAM2 NEB MAP3K5 PIK3R4 CEP170 KANK1 DENND1B ARHGAP21 DYNC1H1 ARAP2 TICRR RPS6KA4 DOCK9 FAM117B EML3 KIAA1671 APPL1 TANC1 CDK11B PEAK1 PLCH1

1.47e-05101421827int:YWHAB
InteractionNUP43 interactions

PDS5B USP34 HIVEP1 CENPC CCDC168 RCC2 FSIP2 TONSL NKTR TAF6 GNL3 NPM1 NUP214 ATAD2 YEATS2 RIF1 POLR1E EHMT1 CCT8 CDK11B

1.61e-0562521820int:NUP43
InteractionDNAI2 interactions

PIK3R4 TONSL OXSR1 GCN1 RPS6KA4 CCT8 CDK11B

2.56e-05802187int:DNAI2
InteractionRFXANK interactions

EHMT2 TONSL PRR14L OXSR1 IQGAP3 RPS6KA4 CASP2 CDK11B HDLBP

3.09e-051462189int:RFXANK
InteractionEEF1AKMT3 interactions

USP34 VPS13C NAB1 MAP3K5 TONSL OXSR1 HERC1 GCN1 RPS6KA4 KIAA1671 CHEK2 CCT8 CDK11B HDLBP

4.53e-0536421814int:EEF1AKMT3
GeneFamilyAnkyrin repeat domain containing

ANKRD37 AGAP11 NUDT12 KANK1 EHMT2 ASB6 CASKIN1 NFKBIE TONSL ARAP2 ANKRD35 ANK3 ANKRD33 EHMT1 TANC1

7.04e-1024214115403
GeneFamilyWD repeat domain containing

BRWD3 PIK3R4 PLAA WDR90 HERC1 WIPI1 EML3 WDR47 PWP1 WDR87 WDFY3 CFAP57

1.01e-0626214112362
GeneFamilyNon-clustered protocadherins

PCDH19 PCDH20 PCDH1

9.70e-0512141321
GeneFamilyZinc fingers BED-type|Pseudoautosomal region 1

ZBED4 ZBED6

8.87e-046141264
GeneFamilyMyosins, class I

MYO1A MYO1E

1.64e-03814121097
CoexpressionGSE22886_TH1_VS_TH2_12H_ACT_UP

CDR2 PLXNB2 RBM15B COL6A3 ASRGL1 ANK3 L1TD1 RAB3GAP1 PAM APPL1 SMAD7

1.14e-0619922211M4507
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

CENPC MAML1 MAP3K5 PIK3R4 CEP170 KANK1 ZBED4 DOCK9 E2F5 RIF1 WDFY3 DOP1A SMAD7

1.89e-0630022213M8702
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

CENPC ERC1 VPS13C PRR14L HERC1 ARAP2 TICRR ATAD2 YEATS2 RIF1

3.38e-0618022210M8239
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN

PDS5B CENPC CTIF ARAP2 WWP1 DOCK9 E2F5

8.02e-06852227M10575
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

BDP1 PDS5B CENPC VPS13C CEP170 PPARGC1A NUDT12 NKTR NPM1 ASRGL1 WWP1 L1TD1 XRCC4 ATAD2 RIF1 APPL1 EXOC1 PUS7L

1.36e-0565622218M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

PDS5B USP34 HIVEP1 CENPC ERC1 SPART CTIF PIK3R4 CEP170 OXSR1 DMD ARAP2 WWP1 DOCK9 E2F5 XRCC4 RIF1 RAB3GAP1 UPF2 WDFY3 SMAD7

1.40e-0585622221M4500
CoexpressionPARENT_MTOR_SIGNALING_UP

USP34 VPS13C MPDZ MAP3K5 EHMT2 FAM120C GLUD1 CCHCR1 DOCK9 EML3 INTS6 RAB3GAP1 GTF2H3 PDE4DIP ENPEP SERPIND1

2.96e-0556722216M16909
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN

ARHGAP32 NFKBIE ARAP2 MIA3 DOCK9 LAMA5 HBP1 SETBP1 SMAD7

5.33e-051992229M9418
CoexpressionGSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP

USP34 CDR2 MPDZ CEP170 NFKBIE COL6A3 IFIT3 RASGRP1 SMAD7

5.33e-051992229M8381
CoexpressionGSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP

NAB1 CEP170 NFKBIE IQGAP3 THEMIS2 IFIT3 FAM135B TMEM132E PIK3R5

5.54e-052002229M7529
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_500

MYH7 ANKRD37 LAMA1 GFRA1 PPARGC1A SALL1 PKHD1 VAV3 ANK3 ICA1 L1TD1 LAMA5 NUP214 PLCH1 HDLBP

2.24e-0540621915gudmap_developingKidney_e15.5_ureter tip_500_flank cortic collct
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000

MYH7 ELP5 ANKRD37 LAMA1 GFRA1 PPARGC1A SALL1 DENND1B PKHD1 VAV3 GCN1 ASRGL1 ANK3 ICA1 L1TD1 LAMA5 SALL4 NUP214 RIF1 TLR3 PLCH1 HDLBP

3.03e-0580121922gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 NCAM2 NEB PPARGC1A PKHD1 DMD SALL4 APOB ASXL3 UNC13C PLCH1

2.59e-09184224112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 NCAM2 NEB PPARGC1A PKHD1 DMD SALL4 APOB ASXL3 UNC13C PLCH1

2.59e-09184224112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 NCAM2 NEB PPARGC1A PKHD1 DMD SALL4 APOB ASXL3 UNC13C PLCH1

2.59e-0918422411ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 LAMA1 MTMR10 PPARGC1A KANK1 DENND1B PKHD1 VAV3 ANK3 SETBP1 WDFY3

3.43e-0918922411830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 USP34 CENPC VPS13C ADAR NKTR DYNC1H1 ARAP2 IFIT3 BRD7 SIGLEC1

6.20e-092002241112f1685ce8f218433068e090c9d839cd5a1910bf
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C PPARGC1A COL14A1 VAV3 DMD ARHGAP21 AKAP6 ZBED6 PAM HDLBP

2.26e-0817622410749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

NAB1 MAML1 MPDZ RCC2 SALL1 DMD MCUB E2F5 RASGRP1 PLCH1

7.19e-0819922410358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

ATG2A DENND1B PKHD1 COL14A1 NKTR HERC1 ARAP2 CFAP57

4.29e-071352248ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

NEB PPARGC1A DMD AKAP6 PRUNE2 ANK3 PDE4DIP PAM TANC1

4.93e-0718822496d249fe92d51a19da19ec14bb2262d394255d577
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NCAM2 ABCA8 COL14A1 AKAP6 VWA3A COL6A3 UNC13C ENPEP PDZRN3

5.15e-071892249203c80030df08ae112f9ae4043709f455d87ce89
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYH7 PPARGC1A DMD AKAP6 ANK3 PDE4DIP PAM TANC1 PDZRN3

5.15e-0718922490a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

MYH7 PPARGC1A KANK1 DMD AKAP6 ANK3 PDE4DIP PAM PDZRN3

5.38e-071902249fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAVCR1 KANK1 PKHD1 PRUNE2 ANK3 FAM135B KIAA1671 MLXIPL ENPEP

5.63e-0719122491c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAVCR1 KANK1 PKHD1 PRUNE2 ANK3 FAM135B KIAA1671 MLXIPL ENPEP

5.63e-0719122493c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

MYH7 PPARGC1A KANK1 DMD AKAP6 ANK3 PDE4DIP PAM PDZRN3

5.63e-07191224925f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

MYH7 PPARGC1A AKAP6 ANK3 PDE4DIP PAM TANC1 NNT PDZRN3

5.88e-071922249ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP34 ARHGAP32 ERC1 HLCS DMD HERC1 DIP2B ANK3 WDFY3

7.93e-07199224994b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP32 SPTBN5 INTS2 FAM120C LAMA5 ZKSCAN3 BRD7 DOP1A

8.63e-07148224810dcbdb47cac908648d9d652c8095b536db19b8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6E NCAM2 ABCA8 CASKIN1 DMD PCDH20 FAM135B C13orf46

2.04e-061662248f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6E NCAM2 ABCA8 CASKIN1 DMD PCDH20 FAM135B C13orf46

2.04e-0616622480f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6E NCAM2 ABCA8 CASKIN1 DMD PCDH20 FAM135B C13orf46

2.04e-061662248e941df9a1091164edde3def8fc7d410186b2bd88
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6E NCAM2 ABCA8 CASKIN1 DMD PCDH20 FAM135B C13orf46

2.04e-061662248aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

CCDC168 DMD AKAP6 ANK3 APOB TMEM132E PDE4DIP

2.55e-0612022473b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH7 MYO1A ARID5A DMD AKAP6 PDE4DIP PDZRN3

2.85e-0612222471cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRPC6 NCAM2 ABCA8 VWA3A COL6A3 SETBP1 ENPEP PDZRN3

3.89e-0618122489ede19228ba5c0668a9c06c915510b95585216ef
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 DMD AKAP6 ANK3 SLC39A10 XRCC4 PDE4DIP PAM

4.05e-061822248287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

NCAM2 ABCA8 ZNF418 ANKRD35 COL6A3 WIPI1 FAM117B PDZRN3

4.75e-0618622481bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

NCAM2 ABCA8 ZNF418 ANKRD35 COL6A3 WIPI1 FAM117B PDZRN3

4.75e-06186224859db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

LGR4 HAVCR1 PPARGC1A PKHD1 RASAL1 PRUNE2 ANK3 ENPEP

4.95e-061872248d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDS5B VPS13C MCC GNL3 NPM1 ASRGL1 ANGPT2 PUS7L

5.56e-06190224852c59001a079c76249abbaa3141e9e661b83d9a0
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

MYH7 PPARGC1A DMD AKAP6 ANK3 PDE4DIP PAM TANC1

5.56e-06190224893c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NCAM2 ABCA8 GFRA1 COL14A1 ARHGAP21 SETBP1 ENPEP PDZRN3

6.00e-0619222488d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

TRPC6 MCC LGR4 PPARGC1A KANK1 ANK3 LAMA5 TANC1

6.00e-0619222489b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 DENND1B DYNC1H1 DIP2B ZBED6 APPL1 WDFY3 PUS7L

6.24e-061932248abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NCAM2 ABCA8 GFRA1 COL14A1 ARHGAP21 SETBP1 ENPEP PDZRN3

6.48e-061942248439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

PPARGC1A DMD AKAP6 PRUNE2 ANK3 PDE4DIP PAM TANC1

6.48e-06194224889812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

PPARGC1A DMD AKAP6 ANK3 PDE4DIP PAM TANC1 PDZRN3

6.48e-061942248c3535f7cc0076653c72db582047cff053c322397
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRPC6 ABCA8 COL14A1 NPM1 COL6A3 UNC13C ENPEP PDZRN3

6.48e-061942248a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C NKTR HERC1 DYNC1H1 MIA3 SLC7A14 MLXIPL RIF1

6.73e-0619522487796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 PPARGC1A KANK1 VAV3 ANK3 ICA1 SLC7A14 UNC13C

6.73e-061952248a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C NKTR HERC1 DYNC1H1 MIA3 SLC7A14 MLXIPL RIF1

6.73e-0619522483e519cffa6144a62b06124642a14c9ff39b76554
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA8 SALL1 PCDH19 COL14A1 COL6A3 PAM TANC1 PDZRN3

6.98e-0619622482ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 LGR4 PPARGC1A KANK1 DENND1B PKHD1 VAV3 ANK3

6.98e-061962248eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPC6 NCAM2 ABCA8 GFRA1 COL14A1 PRUNE2 COL6A3 PDZRN3

7.25e-0619722480dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ERC1 KANK1 DMD ANK3 TANC1 WDFY3 PEAK1

7.52e-0619822481996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

TRPC6 NCAM2 ABCA8 COL14A1 COL6A3 SETBP1 ENPEP PDZRN3

7.80e-0619922484bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 MCC HLCS ANK3 ICA1 ERN2 KIAA1671 TANC1

8.09e-062002248d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 HLCS RASAL1 MIA3 ANK3 ICA1 ERN2 TANC1

8.09e-0620022480eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

CENPC RCC2 DENND1B IQGAP3 TICRR XRCC4 ATAD2 CHEK2

8.09e-062002248c9479452ab8c51139522383f745f02171ebbd7e2
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPC6 NCAM2 ABCA8 COL14A1 COL6A3 SETBP1 ENPEP PDZRN3

8.09e-062002248cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

CENPC RCC2 DENND1B IQGAP3 TICRR XRCC4 ATAD2 CHEK2

8.09e-0620022480bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP1 TMEM200B ZNF418 IQGAP3 VWA3A ANKRD33 CFAP57

1.06e-051492247a6406c4c9404271a2f4c615c6cd3265b2d759b12
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAML1 ADAR C2CD2L MCUB RPS6KA4 CASP2 POLR1E

2.31e-05168224793b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAML1 ADAR C2CD2L MCUB RPS6KA4 CASP2 POLR1E

2.31e-051682247e393553208617a023f1646169c892a87c95db3f5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANKRD37 ARID5A ARAP2 CCHCR1 LAMA5 TANC1 MFSD5

2.40e-051692247665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANKRD37 ARID5A ARAP2 CCHCR1 LAMA5 TANC1 MFSD5

2.40e-0516922476614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

MYH7 VAV3 AKAP6 TFEC PDE4DIP SIGLEC1 PIK3R5

2.50e-0517022474232fe937909f93d3736988c707b8f95ce993398
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 PPARGC1A KANK1 PKHD1 VAV3 ANK3 ICA1

2.79e-0517322470c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA1 ATXN7L3 EHMT2 FAM120C POMT2 E2F5 PCDH1

2.79e-05173224723e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-GABAergic_neurons|GW10 / Sample Type, Dataset, Time_group, and Cell type.

HAVCR1 ASB6 COL14A1 VAV3 FAM135B PDE4DIP PDZRN3

3.00e-051752247d4ff1f197ad4086286e86817cbff24fa718293fc
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSIP2 KANK1 RASAL1 SALL4 GTF2H3 ASXL3 RBBP9

3.12e-05176224723fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSIP2 KANK1 RASAL1 SALL4 GTF2H3 ASXL3 RBBP9

3.12e-05176224730adf8f1638c6244586f8101c2590bb964dfae00
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP32 NKTR ARHGAP21 ANK3 SALL4 ERN2 TANC1

3.47e-0517922476e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E ERC1 UGT3A1 KANK1 ANK3 WWP1 RASGRP1

3.72e-051812247aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7|TCGA-Prostate / Sample_Type by Project: Shred V9

C2CD2L CASKIN1 SECISBP2 NELFCD FAM117B E2F5 DNAAF2

3.86e-051822247af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

CCDC168 PCDH20 TANC1 CFAP57 PLCH1 TPH1

3.90e-0512422465ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GFRA1 TONSL ANK3 SLC7A14 PCDH20 SERPIND1 TREML2

3.99e-051832247876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GFRA1 TONSL ANK3 SLC7A14 PCDH20 SERPIND1 TREML2

3.99e-051832247b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAB1 TRPC6 GNL3 NPM1 ATAD2 DNAAF2 CCT8

3.99e-051832247523896bd1a93bdda81a009768baa3a1bdbd108b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA8 GFRA1 COL14A1 DMD COL6A3 SETBP1 TANC1

4.13e-051842247c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GFRA1 VAV3 CCDC136 TMEM132E UNC13C TANC1 PLCH1

4.13e-051842247658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MYH7 DMD AKAP6 ANK3 PDE4DIP PAM PDZRN3

4.13e-051842247ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

DDX19B CDR2 ARMCX4 DENND1B ZBED4 DOCK9 TLR3

4.13e-0518422470e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDS5B VPS13C MCC GNL3 NPM1 ASRGL1 ANGPT2

4.13e-051842247e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

MYH3 TRPC6 STRADB WDR90 ZNF418 ANKRD35 SAMD14

4.28e-051852247a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDR2 KANK1 PKHD1 PRUNE2 RASGRP1 WDFY3 PDZRN3

4.43e-0518622475c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAVCR1 KANK1 PKHD1 PRUNE2 ASRGL1 ANK3 FAM135B

4.43e-051862247b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HAVCR1 PKHD1 PRUNE2 FAM135B MLXIPL PLCH1 ENPEP

4.43e-051862247f28d72b47624b69a580b4429e2be560a26898591
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

COL14A1 DMD AKAP6 PRUNE2 COL6A3 SETBP1 PDZRN3

4.58e-051872247464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYO1E COL14A1 DMD AKAP6 PRUNE2 UNC13C PDZRN3

4.74e-05188224734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 VPS13C NKTR HERC1 DYNC1H1 ARAP2 ZBED6

4.74e-051882247ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPC6 DMD AKAP6 PRUNE2 COL6A3 ANK3 PDZRN3

4.74e-051882247293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 LGR4 PPARGC1A KANK1 VAV3 ICA1 UNC13C

4.74e-051882247eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO1E MAP3K5 VAV3 ANK3 TANC1 PLCH1 PDZRN3

4.74e-051882247b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAVCR1 KANK1 PKHD1 PRUNE2 TFEC FAM135B ENPEP

4.90e-05189224728b502611829e4a24caff2562545c7db97686099
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 LGR4 PPARGC1A KANK1 VAV3 ICA1 UNC13C

4.90e-051892247977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA8 GFRA1 COL14A1 COL6A3 SETBP1 CHEK2 PDZRN3

4.90e-0518922472a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDR2 LAMA1 LGR4 SALL1 PKHD1 VAV3 PRUNE2

5.07e-0519022471cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

TRPC6 MCC PPARGC1A KANK1 ANK3 LAMA5 TANC1

5.07e-051902247ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

NCAM2 ABCA8 GFRA1 COL14A1 COL6A3 SETBP1 PDZRN3

5.07e-0519022477dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MTMR10 PPARGC1A PKHD1 SYT16 RASGRP1 ASXL3 SETBP1

5.07e-0519022474836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 LGR4 PPARGC1A KANK1 VAV3 ICA1 UNC13C

5.07e-051902247e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

MYH7 PPARGC1A KANK1 DMD AKAP6 PDE4DIP PDZRN3

5.07e-051902247de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO1E ANKRD37 MCC ARID5A ASRGL1 DOCK9 SMAD7

5.07e-05190224707b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH7 DMD AKAP6 TMEM132E PDE4DIP PDZRN3

5.08e-051302246a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

PPARGC1A DMD AKAP6 ANK3 PDE4DIP PAM TANC1

5.24e-0519122475d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

CENPC NKTR HERC1 ARAP2 COL6A3 ANK3 DOCK9

5.41e-05192224747646d7e4990be85072987f92bf18d52f8da752e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 UGT3A1 RTN3 NCAM2 MTMR10 RASAL1 ANK3

5.41e-0519222470bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCC CTIF DOCK9 FAM117B IFIT3 KIAA1671 TANC1

5.41e-051922247c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ABCA8 GFRA1 COL14A1 COL6A3 SETBP1 ENPEP PDZRN3

5.41e-051922247a769158c49d2b208c4224d85e7ae68c85cc372ed
DiseaseMuscular Dystrophy, Animal

PPARGC1A DMD

5.09e-0522112C0026851
DiseaseKleefstra syndrome 1 (implicated_via_orthology)

EHMT2 EHMT1

5.09e-0522112DOID:0060352 (implicated_via_orthology)
Diseasefascioliasis (biomarker_via_orthology)

GLUD1 GLUD2

1.52e-0432112DOID:885 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

LAMA1 MCC ABCA8 PKHD1 UGT3A2 DMD AKAP6 TFEC APOB SETBP1 ZKSCAN3 CHEK2 PIK3R5 SMAD7 HR

1.75e-0470221115C0009402
Diseasefat body mass

USP34 SECISBP2 PRUNE2 ASRGL1 FAM135B TMEM132E PAM UNC13C

1.79e-042172118EFO_0005409
Diseasebiliary liver cirrhosis

NAB1 UGT3A1 DENND1B RPS6KA4

2.76e-04442114EFO_0004267
DiseaseX-24544 measurement

UGT3A1 UGT3A2

3.02e-0442112EFO_0800892
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

PDS5B HIVEP1 PKHD1 POC5 EML3 PWP1 SYT16 SETBP1 SKOR1 HR

3.14e-0436421110EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseArthrogryposis

MYH3 DYNC1H1 GFM2

4.36e-04212113C0003886
Diseaseviral infectious disease (implicated_via_orthology)

EHMT2 EHMT1

5.02e-0452112DOID:934 (implicated_via_orthology)
Diseasehepatitis A virus cellular receptor 1 measurement

ABCA8 HAVCR1

5.02e-0452112EFO_0010601
Diseaseurate measurement, bone density

CDR2 ERC1 TRPC6 MCC ABCA8 FSIP2 PPARGC1A SALL1 EHMT2 RASAL1 AKAP6 LAMA5 PEAK1

5.55e-0461921113EFO_0003923, EFO_0004531
Diseasecongenital muscular dystrophy (implicated_via_orthology)

DYNC1H1 COL6A3

7.49e-0462112DOID:0050557 (implicated_via_orthology)
Diseasechildhood absence epilepsy (biomarker_via_orthology)

GLUD1 GLUD2

7.49e-0462112DOID:1825 (biomarker_via_orthology)
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

HAVCR1 EHMT2 APOB MLXIPL

9.06e-04602114EFO_0021898
Diseasefree cholesterol in very large HDL measurement

POC5 WIPI1 APOB MLXIPL

1.02e-03622114EFO_0022273
Diseasefree cholesterol in chylomicrons and extremely large VLDL measurement

HAVCR1 EHMT2 APOB MLXIPL

1.02e-03622114EFO_0022263
DiseaseHyalinosis, Segmental Glomerular

MYO1E TRPC6 HAVCR1

1.03e-03282113C0086432
DiseaseT-cell immunoglobulin and mucin domain 1 measurement

ABCA8 HAVCR1

1.04e-0372112EFO_0010812
DiseaseHyperammonemia

NAGS GLUD1

1.04e-0372112C0220994
Diseasefocal segmental glomerulosclerosis (implicated_via_orthology)

TRPC6 HR

1.04e-0372112DOID:1312 (implicated_via_orthology)
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

MYH7 TMEM43

1.04e-0372112C0751337
Diseaseestradiol measurement

PIWIL1 UGT3A1 EHMT2 UGT3A2 ARHGAP21

1.19e-031102115EFO_0004697
Diseasesquamous cell lung carcinoma

PDS5B NEB ADAR XRCC4 ECPAS CHEK2

1.24e-031652116EFO_0000708
Diseasetotal lipids in very large HDL measurement

POC5 WIPI1 APOB MLXIPL

1.30e-03662114EFO_0022312
Diseasecholesteryl esters to total lipids in large LDL percentage

HAVCR1 APOB MLXIPL

1.40e-03312113EFO_0022249
Diseasetriglycerides in very small VLDL measurement

HAVCR1 EHMT2 APOB MLXIPL

1.45e-03682114EFO_0022144
Diseasecholesterol in very large HDL measurement

POC5 WIPI1 APOB MLXIPL

1.53e-03692114EFO_0022229
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA8 HAVCR1 POC5 MCUB WIPI1 APOB MLXIPL HDLBP

1.60e-033032118EFO_0004612, EFO_0020945
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA8 HAVCR1 POC5 MCUB WIPI1 APOB MLXIPL HDLBP

1.73e-033072118EFO_0004612, EFO_0020946
DiseaseMalignant neoplasm of breast

HLCS CTIF ADAR PIK3R4 DMD AKAP6 THEMIS2 NUP214 PCDH20 RIF1 SETBP1 CHEK2 EHMT1 APPL1 ENPEP DOP1A HDLBP

1.94e-03107421117C0006142
Diseasewhite matter microstructure measurement

DENND1B ARHGAP21 DIP2B DOCK9 APOB XRCC4 SETBP1 ZKSCAN3 WDFY3

2.09e-033902119EFO_0005674
DiseaseFocal glomerulosclerosis

MYO1E TRPC6 HAVCR1

2.16e-03362113C0017668
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0111269 (implicated_via_orthology)
DiseaseInherited focal segmental glomerulosclerosis

MYO1E TRPC6

2.21e-03102112cv:CN327126
Diseaseproteinuria (biomarker_via_orthology)

TRPC6 HAVCR1

2.21e-03102112DOID:576 (biomarker_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0110454 (implicated_via_orthology)
DiseaseFocal segmental glomerulosclerosis

MYO1E TRPC6

2.21e-03102112cv:C0017668
Diseaselevel of Triacylglycerol (51:3) in blood serum

APOB MLXIPL

2.21e-03102112OBA_2045163
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH3 MYH7

2.21e-03102112DOID:0080326 (implicated_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH3 MYH7 PPARGC1A DMD

2.63e-03802114DOID:12930 (implicated_via_orthology)
Diseaseresponse to ondansetron, QT interval

MPDZ TLR3

2.68e-03112112EFO_0004682, EFO_0020997
DiseaseHereditary Nephrotic Syndromes, Autosomal Dominant

MYO1E TRPC6

2.68e-03112112cv:CN043612
Diseaselevel of Diacylglycerol (18:1_18:1) in blood serum

APOB MLXIPL

2.68e-03112112OBA_2045170
Diseasebody fat percentage

PDS5B HIVEP1 PKHD1 POC5 EML3 PWP1 SYT16 SETBP1 SKOR1 HR

2.84e-0348821110EFO_0007800
Diseasesudden cardiac arrest

LAMA1 PKHD1 RAB3GAP1 TANC1

3.01e-03832114EFO_0004278
Diseaseclinical treatment

ICA1 APOB PAM

3.15e-03412113EFO_0007056
Diseasedistal myopathy (implicated_via_orthology)

MYH3 MYH7

3.20e-03122112DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH3 MYH7

3.20e-03122112DOID:2106 (implicated_via_orthology)
Diseaseplatelet component distribution width

PDS5B HAVCR1 HERC1 THEMIS2 PRUNE2 EEFSEC TFEC NELFCD DOCK9 LAMA5 MLXIPL CHEK2 SIGLEC1

3.23e-0375521113EFO_0007984
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

HAVCR1 POC5 MCUB APOB MLXIPL ASXL3

3.26e-032002116EFO_0004611, EFO_0020945
Diseasemetabolic syndrome

HAVCR1 POC5 ARAP2 MIA3 APOB MLXIPL

3.26e-032002116EFO_0000195
DiseaseProfound Mental Retardation

LAMA1 MCC DYNC1H1 CASP2 SETBP1

3.31e-031392115C0020796
DiseaseMental Retardation, Psychosocial

LAMA1 MCC DYNC1H1 CASP2 SETBP1

3.31e-031392115C0025363
DiseaseMental deficiency

LAMA1 MCC DYNC1H1 CASP2 SETBP1

3.31e-031392115C0917816
Diseasetriglycerides in large LDL measurement

HAVCR1 APOB MLXIPL

3.60e-03432113EFO_0022319
Diseaseliver cirrhosis (is_implicated_in)

CENPC ADAR TLR3

3.60e-03432113DOID:5082 (is_implicated_in)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH3 MYH7

3.77e-03132112DOID:397 (implicated_via_orthology)
DiseaseFamilial idiopathic steroid-resistant nephrotic syndrome

MYO1E TRPC6

3.77e-03132112cv:C4273714
Diseasesaturated fatty acids measurement

HAVCR1 APOB MLXIPL

4.10e-03452113EFO_0022304
Diseaseresting heart rate

MAML1 PPARGC1A ARHGAP21 NGDN TANC1

4.44e-031492115EFO_0004351
Diseasefree cholesterol in medium VLDL measurement

HAVCR1 APOB MLXIPL

4.64e-03472113EFO_0022269
Diseaseinsomnia measurement

SALL1 WDR90 ARHGAP21 RASGRP1 TMEM132E ASXL3 PAM PLCH1 PCDH1

4.81e-034432119EFO_0007876
Diseasecerebral amyloid deposition measurement

NAA60 CHEK2 WDFY3 PCDH1

4.87e-03952114EFO_0007707
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, lipid measurement

HAVCR1 MCUB APOB MLXIPL

4.87e-03952114EFO_0004529, EFO_0008317, EFO_0008596
Diseasetotal lipids in lipoprotein particles measurement

HAVCR1 APOB MLXIPL

4.92e-03482113EFO_0022309
Diseasehepatoblastoma (is_marker_for)

SALL1 SALL4

5.03e-03152112DOID:687 (is_marker_for)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH3 MYH7

5.03e-03152112DOID:0050646 (implicated_via_orthology)
Diseasetriacylglycerol 52:3 measurement

APOB MLXIPL

5.03e-03152112EFO_0010415
Diseasehepatic encephalopathy (biomarker_via_orthology)

GLUD1 GLUD2

5.03e-03152112DOID:13413 (biomarker_via_orthology)
Diseaseamenorrhea, response to antineoplastic agent

APOB DERA

5.03e-03152112EFO_0010269, GO_0097327
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

HAVCR1 MCUB APOB MLXIPL

5.06e-03962114EFO_0004530, EFO_0008317, EFO_0008596
Diseasesusceptibility to measles measurement

MYO1E NUDT12 KIAA1671

5.21e-03492113EFO_0008414
Diseaseapolipoprotein B to apolipoprotein A1 ratio

ABCA8 HAVCR1 APOB

5.21e-03492113EFO_0021897
DiseaseParoxysmal atrial fibrillation

USP34 MYH7 HERC1 AKAP6 SMAD7

5.38e-031562115C0235480
Diseasefamilial atrial fibrillation

USP34 MYH7 HERC1 AKAP6 SMAD7

5.38e-031562115C3468561
DiseasePersistent atrial fibrillation

USP34 MYH7 HERC1 AKAP6 SMAD7

5.38e-031562115C2585653
DiseaseAlzheimer disease, APOE carrier status

TRPC6 ATG2A COL6A3 FAM135B

5.44e-03982114EFO_0007659, MONDO_0004975
Diseaseatrial fibrillation

USP34 MYH7 HERC1 ARHGAP21 CCDC136 AKAP6 ENPEP SMAD7

5.45e-033712118EFO_0000275
Diseaseblood urea nitrogen measurement

PPARGC1A PKHD1 WDR90 DMD NELFCD DOCK9 MLXIPL SETBP1 TANC1

5.47e-034522119EFO_0004741
Diseasediabetic retinopathy (implicated_via_orthology)

PPARGC1A ANGPT2

5.72e-03162112DOID:8947 (implicated_via_orthology)
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

POC5 APOB MLXIPL

5.83e-03512113EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
DiseaseAtrial Fibrillation

USP34 MYH7 HERC1 AKAP6 SMAD7

5.98e-031602115C0004238
Diseasephospholipids:total lipids ratio

ABCA8 HAVCR1 POC5 WIPI1 APOB MLXIPL

6.01e-032272116EFO_0020946
Diseasephospholipids in medium VLDL measurement

HAVCR1 APOB MLXIPL

6.16e-03522113EFO_0022154
Diseasebiological sex

DENND1B PKHD1 ANK3 SETBP1 PEAK1 TPH1

6.39e-032302116PATO_0000047
Diseasemuscular dystrophy (is_implicated_in)

POMT2 COL6A3

6.45e-03172112DOID:9884 (is_implicated_in)
DiseaseLimb Deformities, Congenital

SALL1 SALL4

6.45e-03172112C0206762
DiseaseAcute myeloid leukemia

NPM1 NUP214

6.45e-03172112cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

NPM1 NUP214

6.45e-03172112601626
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

HAVCR1 MCUB APOB MLXIPL

6.47e-031032114EFO_0008595, EFO_0020944
Diseasecholesterol in small VLDL measurement

HAVCR1 APOB MLXIPL

6.49e-03532113EFO_0022228
Diseasehypertension

TRPC6 MCC PLXNB2 TICRR COL6A3 XRCC4 ENPEP

6.81e-033072117EFO_0000537
Diseasetotal lipids in medium VLDL

HAVCR1 APOB MLXIPL

6.84e-03542113EFO_0022153
DiseaseMetastatic melanoma

STRADB OXSR1 PEAK1

6.84e-03542113C0278883

Protein segments in the cluster

PeptideGeneStartEntry
STDEHLVKDLGSLNG

CEP170

51

Q5SW79
VHGIKGTSISSEVNL

BDP1

2171

A6H8Y1
LGSKRSLEEEGAAHS

ARID5A

441

Q03989
KALESHADTIGSGRA

AGAP11

106

Q8TF27
KLEDTAGDTGHSSLE

CTIF

281

O43310
DSLLDVLTKGGHSRT

BRD7

461

Q9NPI1
VSTTGHGESILKVNL

ASRGL1

216

Q7L266
VSLGHLAKGASLDDL

RASGRP1

51

O95267
IHLKGLTGTAGKISS

ANGPT2

401

O15123
LDGAGKTSVLHSLAS

ARL9

26

Q6T311
KEKSHLSTSESGELG

BRWD3

1596

Q6RI45
GDSEHKLETSSGRVL

PAM

896

P19021
THKIVDAIGAIAGSS

DOP1A

1971

Q5JWR5
SDDVHSLGKVTSDLA

EHMT2

211

Q96KQ7
HCSDRSTLGSIKEGI

ARAP2

1426

Q8WZ64
KGSAEVAELLLSHGA

ANKRD35

196

Q8N283
DSVGGLSNHIAALKE

ATAD2

426

Q6PL18
GKTALLHALASSDGV

ASB6

171

Q9NWX5
GDDDLKETGFHLTTT

CDK11B

766

P21127
LGSSHTKVLTDFDGR

FAM187A

71

A6NFU0
STDIVDGNHKLTLGL

DMD

96

P11532
ITDFGHSKILGETSL

CHEK2

366

O96017
LLTVGSGETKDHVLG

ARMCX4

2171

Q5H9R4
LSAVSLTDHEGLADK

ATG2A

301

Q2TAZ0
KKSHLSLVGTASGLG

ATXN7L3

311

Q14CW9
HLEQKGLGEVSLSSA

ASXL3

1966

Q9C0F0
DGLKHLLETGASVNA

ANKRD37

11

Q7Z713
TVSLGAGAKDELHIV

NPM1

46

P06748
DTVGHDDIIGKISLS

RASAL1

76

O95294
GSCAAHSLLITTEGK

RCC2

156

Q9P258
EGDQGVISSLLKDHT

RBM15B

741

Q8NDT2
EVLAKLGTSAEGAHL

RAB3GAP1

656

Q15042
LDLKEHASSLASSGL

ERC1

676

Q8IUD2
KSLTLVLHRDSGSLG

PDZRN3

246

Q9UPQ7
TILHSDGDLTEQGKI

PDS5B

856

Q9NTI5
EGGVLDHLVTATTSL

ANKRD33

301

Q7Z3H0
GSKLTTTSGVQDELH

INTS6

131

Q9UL03
LLLSGDSVFSKDSHG

PCDHGA12

791

O60330
DLTEQLGSSGKTIHE

MYH7

1511

P12883
GEHKSGVLDESTIAT

OXSR1

111

O95747
SLGLKGETHEQVHSI

SERPIND1

166

P05546
HGIKDLSTQLSRTGT

ABI3

151

Q9P2A4
DHGKTSLSASALVLI

PCDH19

646

Q8TAB3
DEKTIIIGHSSGAIA

RBBP9

66

O75884
RKLDGSESHSVLGSS

RSPH10B

371

P0C881
RKLDGSESHSVLGSS

RSPH10B2

371

B2RC85
DALQSSGKHSLGLDS

MAML1

171

Q92585
IGGSVLESHKLTILA

PCDH20

386

Q8N6Y1
GRKDEVISSLSHAIG

POC5

226

Q8NA72
HAGSEGVKLLATVLS

CASKIN1

406

Q8WXD9
TSAESKGGSLHSVLV

FOXB2

416

Q5VYV0
KAGIEAHSEAKTSGL

MCUB

206

Q9NWR8
HLSSGVLKDIFTTGT

KIAA0895

91

Q8NCT3
KGVVLSGAESLLEHS

KIAA1671

1041

Q9BY89
EKGHDASQITLALGT

NELFCD

271

Q8IXH7
TDGDHLSSLLNKTTV

DNAAF2

781

Q9NVR5
SLGGSITAFHKLSLL

MTMR10

671

Q9NXD2
GIGSLLLESLKDHIS

NAA60

111

Q9H7X0
SEAKSHSSESLGILK

NAB1

451

Q13506
SSVGSKGDFLLVSEH

MYO1A

961

Q9UBC5
SLENISSLKGHTGKI

CFAP57

501

Q96MR6
AVGSDHTLKEIADSL

CFAP57

571

Q96MR6
LDGSLHALSKQTGDL

ERN2

46

Q76MJ5
IDVQEGTSGKTALHL

NFKBIE

396

O00221
GTSGKTALHLAVETQ

NFKBIE

401

O00221
GSLEAKSTHHETLGL

MFI

191

Q8NCR3
GGSTKSETEDSILHQ

APPL1

486

Q9UKG1
HATLLGVVKEGSTSA

HERC1

2331

Q15751
HVDSEGEIKSGQLSL

HLCS

406

P50747
FGHLDSKTGSEASVL

FSIP2

1126

Q5CZC0
STGLAKHLLSGLGDR

HR

551

O43593
EGSGFTKLHLVESLL

ECPAS

831

Q5VYK3
NLDTVKGSSLHVGSD

PLXNB2

691

O15031
HISDGVADSGLTLKG

RHOT1

236

Q8IXI2
GKSQETLHGVLTRSD

MINDY4B

321

A8MYZ0
QIGSHSGAITLEKEI

PCDH1

766

Q08174
GKHVILSGSTEVISN

PEAK1

206

Q9H792
LDTDLHSLAQIGGKS

FAM214B

186

Q7L5A3
GLGVALTLDHTKNEA

INTS2

276

Q9H0H0
TLSHGEVKGTSGSLA

DIP2B

191

Q9P265
THDTTGLTAKELEAL

NENF

111

Q9UMX5
GSTALSIALEAGHKD

KANK1

1301

Q14678
VSLSLAKHLGVSGAS

LMLN2

356

A0A1B0GTW7
ETTESLHGDISSLKT

NUP214

756

P35658
LHGDISSLKTTLLEG

NUP214

761

P35658
TGTVHLESLTLTGTK

LGR4

316

Q9BXB1
ESLTKHLFAILGGSE

GCN1

336

Q92616
SEGHIVLTDFGLSKE

RPS6KA4

171

O75676
TGGLRDSSHKVLSNV

NAGS

296

Q8N159
AGDHVTKLLRSSVLG

ENPEP

736

Q07075
AGTEATLGHAKTLLA

LAMA5

2266

O15230
GGLAKALSTLSAHVT

OR4F15

231

Q8NGB8
TGLLSVAEGKESRHA

ARHGAP32

1801

A7KAX9
GESIAADGHTDLSKL

IQGAP3

1326

Q86VI3
ADGHTDLSKLEVSLT

IQGAP3

1331

Q86VI3
AQLSKSSVLTGGHEE

PPARGC1A

356

Q9UBK2
SHGLELNADILGTDK

APOB

1621

P04114
STAKGAVDHKLSLES

APOB

3471

P04114
LGTHKIEDGTLASKT

APOB

3931

P04114
ELSELHSAALASLKG

MCC

16

P23508
GGSSRHEKSLGLLTT

E2F5

46

Q15329
SLHKDLLGAISGIAS

DOCK9

1221

Q9BZ29
GEGKATTAHDLSGKL

ADAR

151

P55265
TGSTGALETRSLKDH

C2CD2L

621

O14523
EKEGLGASSHITTKS

GFRA1

421

P56159
LDSGEHKTSVLEESG

CENPC

671

Q03188
SSLAGSDIVKGHEET

CDR2

316

Q01850
RISGASEKDIVHSGL

GLUD1

496

P00367
KIGETHTDIELSGLL

COL14A1

491

Q05707
DLTLKGSGHSLTVTT

FAM117B

526

Q6P1L5
IVVLTDGHSKDGLAL

COL6A3

146

P12111
AELSKEGHQVALLSG

DDX19B

351

Q9UMR2
KQGSSDGVSKSLELH

FAM120C

1011

Q9NX05
DTAVQHGLEGLSISK

IFIT3

376

O14879
HSVLLVGFGSVKSEE

CTSW

291

P56202
LLLDTLKESGSPGHS

DHRSX

161

Q8N5I4
EGDASKSSISDILLH

AKNAD1

101

Q5T1N1
LLDHGASLSITTKKG

ANK3

551

Q12955
LSLHEEEGSSGSEQK

ANK3

4341

Q12955
HEEALSSLTSKAEGL

CCHCR1

186

Q8TD31
STGDFDLHLLKVSEG

IL7

96

P13232
KVIGVHSSLAGSILS

MS4A6E

46

Q96DS6
KEALELTDTGLLSGS

DYNC1H1

1301

Q14204
SSGLTNGIIEEKDIH

GNL3

456

Q9BVP2
GLKLLSHEESVSFGE

HBP1

261

O60381
SGVALGHLKAASEAS

C13orf46

21

A0A1B0GUA9
ETESLHGSSGKLTGS

EXOC1

456

Q9NV70
SSVGKVSVLGLLHEE

ELP5

156

Q8TE02
DSHLVSLGGKDASIF

EML3

851

Q32P44
KLLGSLSGSLTTVFH

CCDC168

7066

Q8NDH2
TLHELSTLGKGIDQE

FAM135B

611

Q49AJ0
SKETLEAHGASISGT

GPRIN1

106

Q7Z2K8
HLKTILATGELGTLT

DERA

186

Q9Y315
ILDTLSTHSSDQGKL

DENND1B

571

Q6P3S1
QKGHTGIKSDSLTLS

SAMD15

631

Q9P1V8
NGGALDLTSSHAEKI

SALL1

966

Q9NSC2
HSGSDLKETGIANIA

SLC39A10

656

Q9ULF5
ALHSSGAGADTLKTL

SALL4

246

Q9UJQ4
SKGEKDLGASSLHVN

EHMT1

326

Q9H9B1
GGDVDHSTLVTLFKL

CASP2

221

P42575
SISGASEKDIVHSAL

GLUD2

496

P49448
LGLLVLHDSDRKTGT

MFSD5

391

Q6N075
ALAGALSKSSSIHDV

LRRC74B

126

Q6ZQY2
HEVLADLGSKTLTGL

PRSS56

506

P0CW18
HTSSSIKLSEEGLEG

PRR14L

891

Q5THK1
EEASTGSHLKLIVDA

UPF2

556

Q9HAU5
DGKSILSALDKGSTH

ICA1

321

Q05084
ETVGATLETLHFGKL

MAP3K5

121

Q99683
TLGVHEADLLKTSGT

NNT

136

Q13423
NLDHVKESKTGSSGI

PIWIL1

96

Q96J94
VAAGSEEDHKLGTLS

POLR1E

386

Q9GZS1
EIHNTGLTILHGEKS

RTN3

91

O95197
GLTILHGEKSHVLGS

RTN3

96

O95197
SIAGLAELGHDVIKT

TAF6

376

P49848
DGLTLDVTGTHLVEK

SKOR1

841

P84550
STKSGDTLLLLHHGD

TMEM43

276

Q9BTV4
THLDNILKSGTVTTG

TREML2

136

Q5T2D2
NIALTVGLKHTATGD

GFM2

431

Q969S9
SGTSESEALISHLDK

PRUNE2

1271

Q8WUY3
GDLSLSLVTVGKHLT

POMT2

266

Q9UKY4
KFSRSLLTHGEDGTE

SYT16

226

Q17RD7
SGSCIEHSKSLDLGL

TMEM200B

251

Q69YZ2
SELLTGAKHSTATVD

TMEM132E

356

Q6IEE7
EGDALVNGAKLHTLS

MIA3

596

Q5JRA6
LSGKHDTVTVSSDLD

NKTR

1066

P30414
KGSHIDETALSLLIS

PUS7L

666

Q9H0K6
KGSNLHEKTLGETSA

RIF1

1481

Q5UIP0
SHADVIIKGNGLTLS

LAMA1

606

P25391
ILHLADSVAGSVKVG

HAVCR1

11

Q96D42
VSSSSHLLGTKLGPE

ST6GALNAC6

111

Q969X2
IQSKGGLDDTLHTII

SECISBP2

701

Q96T21
LSAKSLSHAKGGSVL

SLC5A9

306

Q2M3M2
GHLSTVEFLLSKGAA

TANC1

1156

Q9C0D5
DGSKLKSLGLSNSHD

SAMD14

361

Q8IZD0
IHFGTTGKLASADIE

MYH3

251

P11055
AEGDIAKLTGILSHS

NUDT12

21

Q9BQG2
DLDGSLSGKNRSHIL

PKHD1

2526

P08F94
KLGFDTLHGLVSTLS

MLXIPL

666

Q9NP71
KGEDGGHSLSSVRTL

SPTBN5

3236

Q9NRC6
ITAILGHSGAGKSTL

ABCA8

511

O94911
VSENLGSHGKEISES

AKAP6

1916

Q13023
GSLSVNKHRGLSLTE

CCDC136

41

Q96JN2
HDSSQKGVIDLAALG

PIK3R4

811

Q99570
LEGTGTTTAHGTKLA

SLC7A14

36

Q8TBB6
GKKSSSAEGHTDAVL

PWP1

246

Q13610
GAGLLSSISELKHAL

TPH1

331

P17752
TCGLTSHDKRISDLG

WDR47

321

O94967
EAAKILTISTLGGSH

UGT3A1

21

Q6NUS8
LKVHLSTGELGIIDS

EEFSEC

506

P57772
GGAEADLKALTHSVL

SMAD7

86

O15105
GHLLRGISISSKESE

SPART

51

Q8N0X7
LGHTDKVSALALDGS

WDR90

406

Q96KV7
TLDLSHNGLSSTKLG

TLR3

151

O15455
GSLSLLESEGKDHGL

TICRR

1711

Q7Z2Z1
ADTNTVLGELVKHGT

ZC3H12A

76

Q5D1E8
LGISKDHSRILVGDS

WDFY3

3416

Q8IZQ1
DIATGKLLHTLEGHA

WDR61

176

Q9GZS3
SSDGERTLHGLKLGA

UNC13C

166

Q8NB66
DTLSGVIIKSLTEHG

MPDZ

1501

O75970
DLTHLILDKASGGSL

NGDN

66

Q8NEJ9
GSSSLHIKDVKLSDS

NCAM2

361

O15394
ELGHSAATRAIKASG

PIK3R5

696

Q8WYR1
GTLLHLELSSVAAGK

TONSL

1216

Q96HA7
HSSEGGVKSSQVLGL

THEMIS2

566

Q5TEJ8
KTLESGFVITLTDGH

XRCC4

26

Q13426
ELSHATIDSKTGDLG

PLAA

316

Q9Y263
HLSLSLGSGGEESDK

VPS13C

3336

Q709C8
ELALSHDGKVLATSS

SIGLEC1

1376

Q9BZZ2
FVEGKSILSGSVLSH

PLCH1

1116

Q4KWH8
EVGKDLLTSSGVLKH

ZNF773

151

Q6PK81
DLLSDTLHGEKSTGS

ZBED6

341

P86452
TLHGEKSTGSQDLTA

ZBED6

346

P86452
SSGLLLQEATHTGEK

ZNF418

171

Q8TF45
HGSLVSLGDEKQTKS

ZKSCAN3

246

Q9BRR0
TSLHIESLSLGDEGI

VSIG10

86

Q8N0Z9
KASHILISGDGLVTL

STRADB

186

Q9C0K7
ASLGTVDLGAHVTKQ

TFEC

236

O14948
TGAHLELSLAKDQGL

HDLBP

111

Q00341
GILGSHEDLSKLSLD

TRPC6

811

Q9Y210
IEGTGISSHLKALSD

USP34

1191

Q70CQ2
THSLLGSGTTEENKE

WIPI1

356

Q5MNZ9
EAAKILTISTVGGSH

UGT3A2

21

Q3SY77
SHDLKLGGSNILVTE

WWP1

736

Q9H0M0
TLLASLGLASSKTHE

ZNF419

61

Q96HQ0
LLAQKSSHLEETGSD

ARHGAP21

1531

Q5T5U3
GKATGFSSHILSERL

SETBP1

1176

Q9Y6X0
KILGSGISSSSVLHG

CCT8

206

P50990
AHTLLTAGSDSLIKE

WDR87

256

Q6ZQQ6
SGSLKVIGISQEESH

HIVEP1

1171

P15822
GQHTETLLAGSLAKA

GTF2H3

126

Q13889
GEDTLSKIHSLLTKG

VWA3A

1116

A6NCI4
SGKATVSGLLKIHSS

YEATS2

1026

Q9ULM3
AGDTVELLKGDAHSL

VAV3

621

Q9UKW4
ASIGKTLNEGEHSSV

ZBED4

811

O75132
IDSKHRAGEITSDGL

L1TD1

341

Q5T7N2
EIGNLKSSHSGVLEI

L1TD1

631

Q5T7N2
IEGASAEQKHSLGIT

MYO1E

216

Q12965
GSKGIHELRSSTSAL

PDE4DIP

2226

Q5VU43
ASALSISGGEEKSEH

NEB

6541

P20929