Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

SOX5 ZNF410 HIVEP2 ZSCAN4 MYT1 ZNF521 SALL4 ZNF236 ZBTB24 TBX18 BPTF ZSCAN32 EEF1D SALL1 SNAPC4 MGA TET3 NPAS2 ZNF646

8.42e-0612449819GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

SOX5 ZNF410 HIVEP2 ZSCAN4 MYT1 ZNF521 SALL4 ZNF236 ZBTB24 TBX18 BPTF ZSCAN32 EEF1D SALL1 SNAPC4 MGA TET3 NPAS2 ZNF646

1.14e-0512719819GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

SOX5 ZNF410 HIVEP2 ZSCAN4 MYT1 ZNF521 SALL4 ZNF236 CIC ZBTB24 TBX18 BPTF ZSCAN32 EEF1D SALL1 SNAPC4 MGA TET3 NPAS2 ZNF646

2.29e-0514599820GO:0000977
GeneOntologyMolecularFunctionphosphatase binding

INSR SYTL2 CEACAM8 AMBRA1 PPP1R3A VCAN CABIN1

3.24e-04264987GO:0019902
GeneOntologyMolecularFunctionprotein phosphatase binding

INSR CEACAM8 AMBRA1 PPP1R3A VCAN CABIN1

5.94e-04210986GO:0019903
MousePhenoembryonic lethality during organogenesis

HBS1L AMBRA1 SALL4 F5 TGFBR2 BPTF SALL1 CEP120 TJP1 VCAN LRP1 ANKRD17 CABIN1 MAP2K5 AFF4 GAB1

2.54e-058767916MP:0006207
MousePhenoabsent triquetrum

SALL4 SALL1

3.15e-052792MP:0030862
MousePhenodecreased skeletal muscle cell glucose uptake

CEACAM8 PPP1R3A ARFGEF3 TBC1D4

4.33e-0535794MP:0031618
MousePhenodecreased muscle cell glucose uptake

CEACAM8 PPP1R3A ARFGEF3 TBC1D4

6.69e-0539794MP:0030022
MousePhenoabnormal triquetrum morphology

SALL4 SALL1

9.43e-053792MP:0030861
MousePhenoabnormal skeletal muscle cell glucose uptake

CEACAM8 PPP1R3A ARFGEF3 TBC1D4

1.40e-0447794MP:0031617
DomainZINC_FINGER_C2H2_2

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF804B ZNF646

6.11e-047759612PS50157
DomainZINC_FINGER_C2H2_1

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF804B ZNF646

6.25e-047779612PS00028
Domain-

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF646

7.21e-0467996113.30.160.60
DomainZnf_C2H2-like

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF804B ZNF646

7.72e-047969612IPR015880
DomainZnf_C2H2

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF804B ZNF646

8.51e-048059612IPR007087
Domainzf-C2H2

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF646

8.52e-046939611PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF646

8.62e-046949611IPR013087
DomainZnF_C2H2

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF804B ZNF646

8.79e-048089612SM00355
DomainPTB

TBC1D4 RABGAP1L TNS1

1.13e-0340963SM00462
DomainPTB/PI_dom

TBC1D4 RABGAP1L TNS1

1.22e-0341963IPR006020
DomainTF_T-box

TBX18 MGA

3.38e-0317962IPR001699
DomainTBOX

TBX18 MGA

3.38e-0317962SM00425
DomainTF_T-box_CS

TBX18 MGA

3.38e-0317962IPR018186
Domain-

TBX18 MGA

3.38e-03179622.60.40.820
DomainTBOX_3

TBX18 MGA

3.38e-0317962PS50252
DomainT-box

TBX18 MGA

3.38e-0317962PF00907
DomainTBOX_1

TBX18 MGA

3.38e-0317962PS01283
DomainTBOX_2

TBX18 MGA

3.38e-0317962PS01264
DomainPkinase_Tyr

INSR TGFBR2 MAP3K21 HCK

4.42e-03129964PF07714
DomainSH3

CACNB2 SORBS1 TJP1 MAP3K21 HCK

5.15e-03216965SM00326
DomainSH3

CACNB2 SORBS1 TJP1 MAP3K21 HCK

5.15e-03216965PS50002
DomainSH3_domain

CACNB2 SORBS1 TJP1 MAP3K21 HCK

5.56e-03220965IPR001452
DomainSer-Thr/Tyr_kinase_cat_dom

INSR TGFBR2 MAP3K21 HCK

5.61e-03138964IPR001245
DomainZnf_C2H2_jaz

HIVEP2 ZNF804B

5.65e-0322962IPR022755
Domainzf-C2H2_jaz

HIVEP2 ZNF804B

5.65e-0322962PF12171
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CACNB2 HIVEP2 MYO6 MYT1 SIPA1L3 INSR HECTD4 ZNF236 TASOR2 RLF ARFGEF3 ERGIC1 STK10 BPTF TBC1D4 TJP1 LRP1 ANKRD17 RPRD2 ANKRD12 TET3 AFF4 NPAS2

4.59e-1114891022328611215
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

HIVEP2 UBAP2 SIPA1L3 MBD1 SORBS1 CIC ARFGEF3 TBC1D4 ALMS1 TJP1 RABGAP1L ANKRD17 PLEKHA5 CLINT1 MAP3K21 ARHGAP21 GAB1 PPP1R12C

6.61e-118611021836931259
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SOX5 ZNF410 MYT1 MBD1 SALL4 KDM5D ZNF236 CIC ZBTB24 BPTF SALL1 ACIN1 SNAPC4 MGA NPAS2 ZNF646

1.84e-098081021620412781
Pubmed

A human MAP kinase interactome.

HIVEP2 MYO6 NUP98 SORBS1 CIC ANKRD17 PLEKHA5 MAP3K21 MGA MAP2K5 TNS1 HCK GAB1

2.00e-094861021320936779
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HBS1L CACNB2 DLGAP5 SALL4 TACC2 ATXN1L ZBTB24 SCML2 VCAN ACIN1 ANKRD17 CRYBG1 ANKRD12 MGA TNS1 FUBP3 ARHGAP21 AFF4

2.57e-0910841021811544199
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

UBAP2 SFSWAP DLGAP5 NUP98 CIC TASOR2 BPTF EEF1D SCML2 SALL1 TJP1 ACIN1 RPRD2 CLINT1 MGA FUBP3 AFF4

2.64e-099541021736373674
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RBBP8 ZSCAN4 CIC RLF TBC1D4 SALL1 ALMS1 LRP1 ANKRD17 PLEKHA5 MGA ARHGAP21

3.96e-094181021234709266
Pubmed

Interaction network of human early embryonic transcription factors.

SOX5 HIVEP2 ZSCAN4 NUP98 ZNF521 ATXN1L RLF BPTF SALL1 ALMS1 MGA

7.44e-093511021138297188
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNB2 UBAP2 CENPE SIPA1L3 DLGAP5 HECTD4 SORBS1 TJP1 LRP1 ANKRD17 PLEKHA5 CABIN1 MGA TNS1 ARHGAP21 AFF4

2.16e-089631021628671696
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

UBAP2 SPATA31E1 NUP98 KDM5D CIC TASOR2 STK10 SALL1 CLINT1 MGA GAB1

5.91e-084301021135044719
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

UBAP2 MYO6 DLGAP5 NUP98 TACC2 CIC SCML2 ALMS1 TJP1 ACIN1 ANKRD17 RPRD2 CLINT1 ARHGAP21 AFF4

9.67e-089341021533916271
Pubmed

Human transcription factor protein interaction networks.

BRIX1 SOX5 UBAP2 MYO6 NUP98 ZNF521 ATXN1L CIC RLF BPTF EEF1D SALL1 ALMS1 ANKRD17 RPRD2 CABIN1 MGA FUBP3

1.71e-0714291021835140242
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

HBS1L SIPA1L3 ARFGEF3 TBC1D4 ALMS1 PLEKHA5 ARHGAP21 GAB1

2.01e-07209102836779422
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF410 HIVEP2 ZSCAN4 MBD1 SALL4 KDM5D ZNF236 CIC ZBTB24 TBX18 ZSCAN32 SNAPC4 FUBP3 NPAS2

2.89e-078771021420211142
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

DLGAP5 NUP98 SALL4 KDM5D TASOR2 BPTF EEF1D SCML2 SALL1 CEP120

3.86e-074111021035182466
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

HBS1L UBAP2 BPTF SCML2 ALMS1 TJP1 ACIN1 PLEKHA5 RPRD2 CLINT1 MGA

6.70e-075491021138280479
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

UBAP2 MYO6 SIPA1L3 SORBS1 EEF1D TJP1 CRYBG1 PLEKHA5 CLINT1 ARHGAP21 GAB1

8.87e-075651021125468996
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

UBAP2 DLGAP5 NUP98 EEF1D TJP1 ANKRD17 PLEKHA5 CLINT1

9.33e-07256102833397691
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

SIPA1L3 ALMS1 TJP1 LRP1 RPRD2 ANKRD12 MGA

1.25e-06184102732908313
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

CENPE ZSCAN4 BTBD18 HECTD4 BPTF CLINT1 CABIN1 MGA TNS1

1.30e-06363102914691545
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

BRIX1 SMPD4 CIC STK10 BPTF SCML2 PLEKHA5 RPRD2 FUBP3 ARHGAP21

1.35e-064721021038943005
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MBD1 NUP98 SMPD4 CIC BPTF EEF1D TBC1D4 SALL1 LRP1 ANKRD17 CABIN1 MGA FUBP3

1.40e-068571021325609649
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

UBAP2 CENPE DLGAP5 SYTL2 SMPD4 GGT7 SCML2 ALMS1 TJP1 PLEKHA5 RPRD2 MGA

1.68e-067331021234672954
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SFSWAP RBBP8 DLGAP5 NUP98 CIC STK10 BPTF SCML2 TBC1D4 ACIN1 ANKRD17 SNAPC4

2.94e-067741021215302935
Pubmed

Genome-wide meta-analysis identifies new susceptibility loci for migraine.

SORBS1 TGFBR2 STK10 RABGAP1L LRP1

3.50e-0678102523793025
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

ZSCAN4 SALL4 SALL1 ACIN1 CABIN1

7.48e-0691102520362542
Pubmed

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.

SALL4 SALL1

8.52e-062102219476507
Pubmed

Transcriptomic analysis of CIC and ATXN1L reveal a functional relationship exploited by cancer.

ATXN1L CIC

8.52e-062102230093628
Pubmed

Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family.

SALL4 SALL1

8.52e-062102212395297
Pubmed

Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression.

SALL4 SALL1

8.52e-062102219350679
Pubmed

ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.

ATXN1L CIC

8.52e-062102228178529
Pubmed

Mouse homolog of SALL1, a causative gene for Townes-Brocks syndrome, binds to A/T-rich sequences in pericentric heterochromatin via its C-terminal zinc finger domains.

SALL4 SALL1

8.52e-062102217295837
Pubmed

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors.

GGT7 TGFBR2 TJP1

8.71e-0614102316103213
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CENPE RBBP8 TACC2 SORBS1 CIC ARFGEF3 TBC1D4 SALL1 ALMS1 GAB1

9.35e-065881021038580884
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

UBAP2 MYO6 AMBRA1 CARD6 PLEKHA5 CLINT1 MGA PPP1R12C

9.96e-06353102827545878
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

CENPE SIPA1L3 F5 RLF ARFGEF3 PLEKHA5 MAP3K21 REV1

1.17e-05361102826167880
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

DLGAP5 CIC ZBTB24 RLF BPTF SCML2 SNAPC4 CABIN1 MGA AFF4

1.25e-056081021036089195
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MYO6 SMPD4 ALMS1 TJP1 PLEKHA5 FUBP3 ARHGAP21

1.31e-05263102734702444
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

MYO6 CIC ALMS1 CABIN1 ZNF646

1.44e-0510410259205841
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX5 ZNF410 HIVEP2 MYT1 ZNF236 CIC ZBTB24 TBX18 SALL1 SNAPC4 MGA NPAS2

1.46e-059081021219274049
Pubmed

Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.

SALL4 SALL1 GREM1

1.62e-0517102319168674
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SFSWAP MYO6 INSR NUP98 TASOR2 ARFGEF3 TJP1 CLINT1 MGA ARHGAP21 GAB1

1.82e-057771021135844135
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SFSWAP TMEM165 MBD1 BTBD18 AMBRA1 BPTF ALMS1 LRP1 ANKRD17 MGA AFF4 ZNF646 WDR72

2.38e-0511161021331753913
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

BRIX1 SFSWAP MBD1 DLGAP5 NUP98 CIC BPTF SCML2 ACIN1 RPRD2 CABIN1 MGA FUBP3 TET3

2.55e-0512941021430804502
Pubmed

NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.

NUP98 BPTF

2.55e-053102238940430
Pubmed

Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex.

SALL4 SALL1

2.55e-053102219440552
Pubmed

Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.

HCK GAB1

2.55e-053102215010462
Pubmed

Low-density lipoprotein receptor-related protein 1 polymorphism 663 C > T affects clotting factor VIII activity and increases the risk of venous thromboembolism.

F5 LRP1

2.55e-053102217155964
Pubmed

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L.

ATXN1L CIC

2.55e-053102233115448
Pubmed

Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.

INSR LRP1

2.55e-053102219815552
Pubmed

Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51.

MYO6 TJP1

2.55e-053102220602916
Pubmed

Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro.

INSR GAB1

2.55e-053102210978177
Pubmed

Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex.

SALL4 SALL1

2.55e-053102227471257
Pubmed

Postnatal DNA demethylation and its role in tissue maturation.

INSR TET3

2.55e-053102229795194
Pubmed

Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.

ATXN1L CIC

2.55e-053102220628574
Pubmed

Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse.

INSR IFNGR1

2.55e-05310222852162
Pubmed

The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix.

MBD1 SORBS1

2.55e-053102215777793
Pubmed

Sall4 Is Transiently Expressed in the Caudal Wolffian Duct and the Ureteric Bud, but Dispensable for Kidney Development.

SALL4 SALL1

2.55e-053102223825698
Pubmed

Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.

INSR SORBS1

2.55e-053102211374898
Pubmed

Mechanisms Regulating Acquisition of Platelet-Derived Factor V/Va by Megakaryocytes.

F5 LRP1

2.55e-053102225800007
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBAP2 DLGAP5 HECTD4 AMBRA1 SMPD4 ANKRD17 PLEKHA5 RPRD2 ZNF646

2.66e-05529102914621295
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

UBAP2 SYTL2 ATXN1L CIC ARFGEF3 TJP1 CRYBG1 TNS1 REV1

3.71e-05552102910737800
Pubmed

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development.

SALL4 TBX18 SALL1

4.16e-0523102320159597
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

HBS1L CENPE TMEM165 SIPA1L3 SORBS1 CEP120 ALMS1 TJP1 CLINT1 MGA ARHGAP21

4.25e-058531021128718761
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

HBS1L UBAP2 SFSWAP TJP1 ANKRD17 MGA

4.28e-05215102635973513
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

BRIX1 HBS1L UBAP2 HECTD4 NUP98 AMBRA1 ANKRD17 RPRD2

4.79e-05440102834244565
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

NUP98 SALL4 SALL1 CLINT1 FUBP3

5.04e-05135102531077711
Pubmed

Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways.

MYO6 TJP1

5.09e-054102224942165
Pubmed

CAP defines a second signalling pathway required for insulin-stimulated glucose transport.

INSR SORBS1

5.09e-054102211001060
Pubmed

Regulation and function of Spalt proteins during animal development.

SALL4 SALL1

5.09e-054102219247946
Pubmed

An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.

INSR PLEKHA5

5.09e-054102223518924
Pubmed

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.

ERGIC1 CRYBG1

5.09e-054102222761906
Pubmed

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization.

SIPA1L3 TJP1

5.09e-054102226231217
Pubmed

Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling.

INSR SORBS1

5.09e-054102215031295
Pubmed

Second Heart Field-Derived Cells Contribute to Angiotensin II-Mediated Ascending Aortopathies.

TGFBR2 LRP1

5.09e-054102235143327
Pubmed

Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.

INSR PLEKHA5

5.09e-054102229401624
Pubmed

The vertebrate spalt genes in development and disease.

SALL4 SALL1

5.09e-054102216545361
Pubmed

The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2.

INSR SORBS1

5.09e-054102212504111
Pubmed

Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules.

INSR GAB1

5.09e-05410229658397
Pubmed

The H3.3 chaperone Hira complex orchestrates oocyte developmental competence.

ZSCAN4 CABIN1

5.09e-054102235112132
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

HBS1L MYO6 TACC2 EEF1D SALL1 TJP1 CLINT1 MGA

5.10e-05444102834795231
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

SALL1 RPRD2 CLINT1 MGA AFF4 REV1

5.11e-05222102637071664
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SIPA1L3 SORBS1 TBC1D4 ALMS1 TJP1 PLEKHA5 MAP3K21 FUBP3

5.26e-05446102824255178
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

SFSWAP MBD1 ATXN1L CIC ZBTB24 SALL1 ACIN1 MGA ZNF646

5.65e-05583102929844126
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

BRIX1 MYO6 SIPA1L3 NUP98 F5 TASOR2 EEF1D TJP1 ACIN1 ANKRD17 CRYBG1 PLEKHA5 CLINT1

8.00e-0512571021336526897
Pubmed

Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.

ATXN1L CIC

8.47e-055102232878998
Pubmed

Tumor Suppressor PTEN Regulates Negatively Sertoli Cell Proliferation, Testis Size, and Sperm Production In Vivo.

INSR PLEKHA5

8.47e-055102230576429
Pubmed

Altered expressions and splicing profiles of Acin1 transcripts differentially modulate brown adipogenesis through an alternative splicing mechanism.

INSR ACIN1

8.47e-055102232629174
Pubmed

Critical regulation of TGFbeta signaling by Hsp90.

TGFBR2 TJP1

8.47e-055102218591668
Pubmed

A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.

INSR SORBS1

8.47e-05510229447983
Pubmed

Sall1 is a transcriptional regulator defining microglia identity and function.

TGFBR2 SALL1

8.47e-055102227776109
Pubmed

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.

ATXN1L CIC

8.47e-055102229526553
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HIVEP2 MYO6 SIPA1L3 MBD1 HECTD4 ZNF521 SORBS1 TXNDC11 TJP1 LRP1 CABIN1 ARHGAP21 AFF4

9.97e-0512851021335914814
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DLGAP5 NUP98 TACC2 STK10 TBC1D4 ACIN1 PLEKHA5 RPRD2

1.21e-04503102816964243
Pubmed

Sall1, sall2, and sall4 are required for neural tube closure in mice.

SALL4 SALL1

1.27e-046102218818376
Pubmed

APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes.

INSR SORBS1

1.27e-046102211997497
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

SALL4 BPTF SALL1 CABIN1 MGA

1.38e-04167102520362541
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ATXN1L CIC SCML2 RPRD2 MGA AFF4

1.44e-04268102633640491
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

TASOR2 BPTF EEF1D SCML2 ACIN1 RPRD2

1.53e-04271102632433965
Pubmed

Sall1 plays pivotal roles for lens fiber cell differentiation in mouse.

SALL1 TJP1

1.77e-047102230929925
InteractionYWHAH interactions

HIVEP2 UBAP2 SFSWAP SIPA1L3 HECTD4 SORBS1 ATXN1L CIC PYHIN1 ARFGEF3 TBC1D4 ALMS1 TJP1 RABGAP1L ANKRD17 PLEKHA5 CLINT1 GREM1 MAP3K21 ARHGAP21 GAB1 PPP1R12C

1.40e-0811029922int:YWHAH
InteractionYWHAG interactions

HIVEP2 UBAP2 SIPA1L3 MBD1 HECTD4 SORBS1 CIC PYHIN1 TBC1D4 ALMS1 TJP1 RABGAP1L ACIN1 ANKRD17 PLEKHA5 CLINT1 MAP3K21 ARHGAP21 GAB1 PPP1R12C

2.31e-0612489920int:YWHAG
InteractionHOXA4 interactions

RABGAP1L LRP1 ANKRD17 SNAPC4

3.08e-0621994int:HOXA4
InteractionRCOR1 interactions

SOX5 RBBP8 MYT1 CIC RLF SALL1 ALMS1 RABGAP1L ANKRD17 PLEKHA5 MGA ARHGAP21

5.51e-064949912int:RCOR1
InteractionSMC5 interactions

UBAP2 SFSWAP DLGAP5 NUP98 CIC TASOR2 BPTF EEF1D SCML2 SALL1 TJP1 ACIN1 RPRD2 CLINT1 MGA FUBP3 AFF4

6.91e-0610009917int:SMC5
InteractionSFN interactions

SIPA1L3 INSR SORBS1 TBC1D4 ALMS1 TJP1 RABGAP1L ANKRD17 PLEKHA5 MAP3K21 MAP2K5 ARHGAP21 GAB1 PPP1R12C

7.12e-066929914int:SFN
InteractionPHF21A interactions

RBBP8 CIC RLF TBC1D4 SALL1 ALMS1 RABGAP1L PLEKHA5 MGA ARHGAP21

7.29e-063439910int:PHF21A
InteractionPYHIN1 interactions

BRIX1 MBD1 PYHIN1 VCAN ANKRD17 CRYBG1 CABIN1 MGA FUBP3 ZNF646

1.06e-053589910int:PYHIN1
InteractionPAX6 interactions

SOX5 ZNF410 ZNF521 ATXN1L CIC RLF BPTF SALL1 CABIN1 MGA

1.28e-053669910int:PAX6
InteractionNFIX interactions

SOX5 ZNF521 ATXN1L CIC RLF BPTF SALL1 MGA

1.63e-05227998int:NFIX
InteractionTEAD1 interactions

INSR ATXN1L CIC RLF BPTF SALL1 MGA

2.60e-05176997int:TEAD1
InteractionWWTR1 interactions

HBS1L UBAP2 TGFBR2 BPTF SCML2 ALMS1 TJP1 PLEKHA5 RPRD2 CLINT1

4.32e-054229910int:WWTR1
InteractionFEV interactions

SOX5 ZNF521 ATXN1L CIC RLF SALL1 MGA

6.46e-05203997int:FEV
InteractionFMR1 interactions

CACNB2 UBAP2 TACC2 TJP1 LRP1 ANKRD17 TNS1 FUBP3 ARHGAP21 AFF4 PPP1R12C

6.48e-055369911int:FMR1
InteractionGJD3 interactions

MYO6 TMEM165 INSR SMPD4 GGT7 IFNGR1 TJP1 PLEKHA5 CLINT1 GAB1

7.94e-054549910int:GJD3
InteractionNAA40 interactions

UBAP2 MYO6 DLGAP5 NUP98 TACC2 CIC SCML2 ALMS1 TJP1 ACIN1 ANKRD17 RPRD2 CLINT1 ARHGAP21 AFF4

8.26e-059789915int:NAA40
InteractionHDAC1 interactions

RBBP8 MYT1 NUP98 ZNF521 SALL4 CIC RLF BPTF TBC1D4 SALL1 ALMS1 ANKRD17 PLEKHA5 CABIN1 MGA ARHGAP21

9.49e-0511089916int:HDAC1
InteractionGSK3A interactions

HBS1L SIPA1L3 ARFGEF3 TBC1D4 ALMS1 ACIN1 CRYBG1 PLEKHA5 ARHGAP21 GAB1

9.50e-054649910int:GSK3A
InteractionTFCP2L1 interactions

SALL4 BPTF SALL1 CABIN1 MGA

1.28e-0499995int:TFCP2L1
InteractionODF2 interactions

SIPA1L3 CEP120 ALMS1 TJP1 CLINT1 ARHGAP21

1.30e-04158996int:ODF2
InteractionCNOT9 interactions

UBAP2 SALL1 ALMS1 ANKRD17 RPRD2 MGA FUBP3

1.44e-04231997int:CNOT9
InteractionKIF20A interactions

BRIX1 SFSWAP CENPE MYO6 MBD1 HECTD4 NUP98 AMBRA1 ALMS1 TJP1 RABGAP1L CLINT1 SNAPC4 TET3 PPP1R12C

1.85e-0410529915int:KIF20A
Cytoband6q23.3

HBS1L IFNGR1 ARFGEF3

3.35e-052810236q23.3
Cytoband5p13.2

BRIX1 LMBRD2

2.18e-033110225p13.2
CytobandEnsembl 112 genes in cytogenetic band chr6q23

HBS1L IFNGR1 ARFGEF3

2.42e-031191023chr6q23
CytobandEnsembl 112 genes in cytogenetic band chr6q21

ZBTB24 SLC22A16 CRYBG1

2.54e-031211023chr6q21
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF410 HIVEP2 ZSCAN4 ZNF521 SALL4 ZNF236 ZBTB24 RLF ZSCAN32 SALL1 ZNF646

4.54e-05718651128
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CENPE SYTL2 PPP1R3A ARFGEF3 TNS1 PPP1R12C

4.69e-05181656694
GeneFamilyZinc fingers CXXC-type

MBD1 TET3

8.21e-0412652136
GeneFamilyT-boxes

TBX18 MGA

1.88e-0318652766
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

CACNB2 TJP1

3.91e-0326652904
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 RBBP8 SIPA1L3 TACC2 CRYBG1 CLINT1 WDR72

3.25e-071961017c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR34 NUP98 APLF PYHIN1 PLEKHA5 ARHGAP21

2.42e-061691016d721dbb317a88113b4f76688111908d00f23e899
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 RABGAP1L PLEKHA5

3.96e-061841016ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 RABGAP1L PLEKHA5

4.08e-0618510166baccb26f999145e51b91d94315bf8d4655bef31
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 RABGAP1L PLEKHA5

4.76e-061901016de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 RABGAP1L PLEKHA5

4.91e-06191101625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

CACNB2 INSR TACC2 SORBS1 TBC1D4 PLEKHA5

5.52e-06195101675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

MYO6 MBD1 INSR BPTF ANKRD12 CLINT1

6.21e-061991016fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO6 SYTL2 TACC2 ARFGEF3 PLEKHA5 CLINT1

6.39e-06200101664462a18afca3c1a8548a857924b8166058bf958
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 LMBRD2 F5 PYHIN1 VCAN

8.68e-061221015a2f343962069253a08faa80fd70723b8488a99ec
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

INSR BPTF ANKRD17 ANKRD12 CLINT1

1.58e-051381015817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 SYTL2 NEXN-AS1 MAP3K21 NPAS2

2.00e-051451015bfa196ac1db7acbfcbb2ba9f137036a95e16e091
ToppCellMyeloid-Myeloid-C_(Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

F5 PYHIN1 IFNGR1 VCAN RABGAP1L

2.14e-051471015d7cfec8ec1b4854d783a1bb07b4f8d2b2fd22893
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZSCAN4 TACC2 SYBU ARFGEF3 CLINT1

3.41e-0516210155c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

AMBRA1 LMBRD2 PYHIN1 VCAN TNS1

3.83e-051661015f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZNF521 IFNGR1 VCAN PCDHGB4 LRP1

3.83e-05166101565dafed953b01a9830b54309af75c7a561e88336
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ALMS1 RABGAP1L RPRD2 MAP2K5 TNS1

4.06e-051681015c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYO6 BTBD18 SYTL2 KDM5D PYHIN1

4.06e-051681015b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYTL2 APLF STK10 CEP120 MGA

4.17e-0516910158caf7996796a2e2716e3855de855c903d6126bf2
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS1 SALL1 PLEKHA5 NEXN-AS1 TNS1

4.66e-051731015f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

CENPE DLGAP5 VCAN LRP1 HCK

4.66e-051731015783b8fa08b9d8f597f251793eae164151662f1f9
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

HIVEP2 CIC LRP1

5.19e-05321013ba89b22a5ce8ee9f3099b1fa84721724b94c7759
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

HIVEP2 CIC LRP1

5.19e-0532101358b212d4f2955f06a195df0f79ad95a8ff145b83
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|390C / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 HECTD4 LMBRD2 TBC1D4 CEP120

5.34e-051781015829ea00c022a78d1861aa3ec53503272976775d9
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Treg|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

F5 PYHIN1 TBC1D4 RABGAP1L ANKRD12

5.34e-051781015e37142a84d9713ff1571ce9f976842bf5c17c86f
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO6 ZNF521 SYBU TGFBR2 TJP1

5.63e-05180101530cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRYBG1 MAP3K21 NPAS2 WDR72

5.78e-051811015b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

ZNF521 SORBS1 VCAN GREM1 TNS1

6.41e-051851015e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INSR TXNDC11 RABGAP1L ANKRD12 GAB1

6.41e-0518510153b77bc49cd3740acc025e162a36282ac09e12198
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMEM165 TACC2 SORBS1 VCAN TNS1

6.41e-051851015e58a009aaf342be019a909747b1895d5987d4daf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 ZNF804B PLEKHA5 NPAS2 WDR72

6.57e-0518610155784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

INSR CEACAM8 KDM5D BCORP1 SLC22A16

6.91e-051881015557a0ac069a6ff4e687cac032f64170b9b247165
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

RBBP8 SYTL2 CRYBG1 MAP3K21 WDR72

6.91e-0518810158f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

CACNB2 TACC2 TBC1D4 GAB1 NPAS2

7.09e-0518910159c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 PLEKHA5

7.09e-0518910155e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRYBG1 MAP3K21 NPAS2 WDR72

7.09e-051891015c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

SOX5 MYO6 TACC2 SYBU ARFGEF3

7.09e-051891015f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO6 CRYBG1 MAP3K21 WDR72

7.09e-051891015532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CACNB2 VCAN LRP1 NPAS2

7.27e-05190101545df8fee00f8949937863159d7aa042e72748d9b
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 PLEKHA5

7.27e-051901015fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO6 SIPA1L3 TACC2 CRYBG1

7.45e-0519110153e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 ZNF804B PLEKHA5 NPAS2 WDR72

7.45e-0519110153c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 ZNF804B PLEKHA5 NPAS2 WDR72

7.45e-0519110151c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOX5 NUP98 SMPD4 RLF CRYBG1

7.45e-0519110151ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

INSR ZNF521 TGFBR2 TJP1 TNS1

7.45e-0519110152f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CENPE DLGAP5 ZNF804B MAP3K21 WDR72

7.64e-05192101525378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

RBBP8 SYTL2 CRYBG1 MAP3K21 WDR72

7.64e-051921015760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

INSR RABGAP1L ANKRD17 PLEKHA5 WDR72

7.64e-051921015e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

CACNB2 INSR TACC2 SORBS1 NPAS2

7.82e-051931015dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 SIPA1L3 TACC2 PLEKHA5 WDR72

7.82e-0519310153866667dd221612589ae50f5c52f73a183a49ce6
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO6 ZNF521 SORBS1 SYBU TJP1

7.82e-051931015a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO6 SYTL2 CRYBG1 NPAS2

8.02e-0519410154579b4a44f7c731553a284843c296866027d7c0e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 SIPA1L3 PLEKHA5 NPAS2 WDR72

8.02e-0519410157002937e8903e037332a215d00fbc7c7843b33f2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 RBBP8 PLEKHA5 MAP3K21 WDR72

8.02e-0519410155eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

CACNB2 TACC2 SORBS1 TBC1D4 RABGAP1L

8.02e-051941015c3535f7cc0076653c72db582047cff053c322397
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 RBBP8 SIPA1L3 PLEKHA5 WDR72

8.21e-0519510156477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 SIPA1L3 AMBRA1 RABGAP1L GAB1

8.41e-051961015ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell15-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

CENPE MYT1 DLGAP5 SLC22A16 TNS1

8.41e-051961015511bfc06c34d5add2ae561cca463d1e4e2d43e20
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 SORBS1 VCAN LRP1 GREM1

8.41e-051961015fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

IFNGR1 STK10 VCAN TET3 HCK

8.41e-051961015cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 SORBS1 VCAN LRP1 GREM1

8.41e-051961015802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell15-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

CENPE MYT1 DLGAP5 SLC22A16 TNS1

8.41e-051961015bf2670e5ae996a19987bc70aa5a37d133db789eb
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

MYO6 SYTL2 RELL2 SNAPC4 GAB1

8.62e-0519710158545baf923ddf84c5ce9414a36d810603be52401
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HBS1L SYTL2 F5 PYHIN1 TBC1D4

8.62e-0519710157c9df6025b9d168bd6d041c6cff1e87e08b11847
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO6 SYTL2 TACC2 ARFGEF3 TJP1

8.83e-051981015a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 SIPA1L3 AMBRA1 RABGAP1L GAB1

8.83e-0519810151996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

UBAP2 MYO6 TASOR2 PYHIN1 RELL2

8.83e-051981015717735d755745439f97ba1b71785c73945dfa9c5
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

MBD1 INSR BPTF ANKRD12 CLINT1

9.04e-05199101561b1ed2db71b96157b92b7535d1955a4033098da
ToppCellPSB-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO6 TACC2 ARFGEF3 TJP1 PLEKHA5

9.04e-05199101558dcb0eedafa8629585dc99e53147e2287f49689
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

SOX5 SYBU ARFGEF3 BPTF ANKRD12

9.04e-0519910151b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

MYO6 INSR BPTF ANKRD12 CLINT1

9.04e-051991015d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

SOX5 SYBU ARFGEF3 BPTF ANKRD12

9.04e-0519910154bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

F5 IFNGR1 VCAN LRP1 HCK

9.25e-052001015621af09aae34226902c03edf556562f3ab35a7d8
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFNGR1 VCAN LRP1 TET3 HCK

9.25e-052001015934c2efc780318c66d667ca75be0de350361d351
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

IFNGR1 STK10 VCAN TET3 HCK

9.25e-052001015881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO6 TACC2 ARFGEF3 TJP1 PLEKHA5

9.25e-052001015d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO6 TACC2 ARFGEF3 CLINT1 NPAS2

9.25e-052001015d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

F5 IFNGR1 VCAN LRP1 HCK

9.25e-052001015e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

F5 IFNGR1 VCAN LRP1 HCK

9.25e-052001015b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYO6 SORBS1 SYBU TGFBR2 TJP1

9.25e-0520010157034f57e282982c19c13ee8ab78eabaffa069e30
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CACNB2 SYTL2 VCAN LRP1 TNS1

9.25e-052001015bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell367C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

SYTL2 PYHIN1 TGFBR2

2.65e-045510137916216b3a24f9c6b966aa5392fc2bc43b3d2c4c
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MYT1 SCML2 VCAN PCDHGB4

2.67e-04137101425b5370b63644351efddb8749ef174beca0581cd
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

ZSCAN4 KDM5D BCORP1 BPTF

2.67e-0413710142a5d2a99a2c532480d00b80a4885514a8a5c80fa
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular|TCGA-Stomach / Sample_Type by Project: Shred V9

UBAP2 CENPE F5 MAP3K21

2.75e-04138101493497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 RBBP8 ZSCAN32 MAP3K21

3.32e-041451014fd02d55755c35288a42ab08a82450b370aad35a7
ToppCellControl-B_intermediate-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX5 TBX18 STK10 HCK

3.58e-041481014662c057030effc9eb61216e81d3967e6983c244f
ToppCellHealthy_donor-B_cell|World / disease group, cell group and cell class (v2)

MYT1 ZNF521 GGT7 MAP3K21

3.77e-041501014a2dfed562de7f58f902b547acec5a13853c80c4c
ToppCellHealthy_donor-B_cell|Healthy_donor / disease group, cell group and cell class (v2)

MYT1 ZNF521 GGT7 MAP3K21

3.96e-0415210145768edfde8010324d8594815e73bbfba2c3045f3
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

STK10 SCML2 MGA REV1

4.06e-041531014553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

STK10 SCML2 MGA REV1

4.06e-04153101488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

GPR34 SALL4 TET3 ARHGAP21

4.06e-0415310145424494ea1f09542799045a875cc3eac13de5079
ToppCell(2)_NK/T-(23)_CD4+_T_cell-(230)_CD4+/CD25+_Reg_T_cell|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)

F5 TXNDC11 PYHIN1 TBC1D4

4.16e-041541014059bdf6843f94f5028d4df6aa025865a9edb4521
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9

SOX5 SCML2 TBC1D4 ZNF804B

4.16e-0415410144e9203c220a44c70cd7979796a0b461991422257
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BTBD18 SYTL2 TBC1D4 MAP2K5

4.27e-0415510147aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1_high|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HIVEP2 NUP98 VCAN RABGAP1L

4.27e-041551014cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX5 TACC2 VCAN NEXN-AS1

4.27e-04155101477fdae85d36efb776db977eb424b32487ef222e4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 PYHIN1 VCAN HCK

4.59e-041581014ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 PYHIN1 VCAN HCK

4.59e-041581014ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR34 IFNGR1 RELL2 PLEKHA5

4.81e-041601014398f162e8a75c6cb5c3e4d1832e98d386e1f222b
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

HIVEP2 TACC2 BPTF ANKRD17 PLEKHA5 ANKRD12 MGA NPAS2

8.89e-0717110087535_DN
Drug0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A

HIVEP2 INSR HECTD4 NUP98 TACC2 BPTF ALMS1 PLEKHA5

1.61e-0618510084755_DN
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A

INSR NUP98 TACC2 ALMS1 ANKRD17 PLEKHA5 NPAS2

1.53e-0518110071791_DN
Drug0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A

SFSWAP TACC2 STK10 BPTF ALMS1 PLEKHA5 SNAPC4

1.59e-0518210073630_DN
Drug0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A

CENPE MBD1 DLGAP5 NUP98 TGFBR2 SCML2 VCAN

1.65e-0518310077389_DN
DrugResveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A

CENPE DLGAP5 TGFBR2 SCML2 VCAN GREM1 CABIN1

2.03e-0518910075084_DN
Drugindomethacin, USP; Up 200; 100uM; PC3; HG-U133A

MBD1 AMBRA1 STK10 ZSCAN32 LRP1 ANKRD12 NPAS2

2.25e-051921007452_UP
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; HL60; HG-U133A

CENPE DLGAP5 ZNF236 BPTF ANKRD12 SNAPC4 FUBP3

2.40e-0519410072009_DN
DrugDienestrol [84-17-3]; Down 200; 15uM; PC3; HT_HG-U133A

MBD1 AMBRA1 GREM1 SNAPC4 CABIN1 MAP2K5 NPAS2

2.74e-0519810075727_DN
Diseasepain

SOX5 RBBP8 TGFBR2 RABGAP1L LRP1 RPRD2

5.34e-05196996EFO_0003843
Diseasebody weight

SOX5 CACNB2 HIVEP2 MBD1 INSR HECTD4 ZNF521 TXNDC11 PPP1R3A BPTF CEP120 RABGAP1L MGA MAP2K5

8.05e-0512619914EFO_0004338
Diseasehematocrit

SOX5 HBS1L HIVEP2 UBAP2 INSR HECTD4 SORBS1 TBC1D4 SALL1 RABGAP1L ANKRD17 ARHGAP21

1.47e-0410119912EFO_0004348
DiseaseAutism Spectrum Disorders

SOX5 SFSWAP CIC TET3

1.96e-0485994C1510586
Diseaseuric acid measurement

SOX5 SIPA1L3 INSR SYTL2 HECTD4 F5 GGT7 NPAS2 WDR72

2.16e-04610999EFO_0004761
DiseaseAcute Confusional Migraine

TGFBR2 LRP1

3.95e-049992C0521664
DiseaseStatus Migrainosus

TGFBR2 LRP1

3.95e-049992C0338489
DiseaseAbdominal Migraine

TGFBR2 LRP1

3.95e-049992C0270858
DiseaseSick Headaches

TGFBR2 LRP1

3.95e-049992C0700438
DiseaseCervical Migraine Syndrome

TGFBR2 LRP1

3.95e-049992C0007852
DiseaseHemicrania migraine

TGFBR2 LRP1

3.95e-049992C0018984
Diseasespleen volume

HBS1L HECTD4 TJP1

4.10e-0443993EFO_0600047
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

INSR PPP1R3A ALMS1 AFF4

4.40e-04105994DOID:9352 (implicated_via_orthology)
Diseasemembranoproliferative glomerulonephritis (implicated_via_orthology)

F5 TGFBR2

4.93e-0410992DOID:2920 (implicated_via_orthology)
Diseaseobsolete_red blood cell distribution width

HBS1L INSR HECTD4 LMBRD2 APLF ZBTB24 TXNDC11 STK10 SLC22A16 RABGAP1L CRYBG1 ANKRD12 ARHGAP21

5.67e-0413479913EFO_0005192
Diseasecoronary artery disease

HBS1L HIVEP2 TMEM165 HECTD4 GGT7 CEP120 LRP1 RPRD2 CABIN1 TNS1 ARHGAP21 WDR72

6.58e-0411949912EFO_0001645
DiseasePolydactyly

SALL4 SALL1 CEP120 ALMS1

6.61e-04117994C0152427
Diseasecreatinine measurement, glomerular filtration rate

SIPA1L3 ALMS1 PCDHGB4 WDR72

6.61e-04117994EFO_0004518, EFO_0005208
Diseasecarotid artery intima media thickness

SOX5 RBBP8 TACC2 SLC22A16 VCAN LRP1 WDR72

8.17e-04450997EFO_0007117
DiseaseMigraine Disorders

TGFBR2 LRP1

8.48e-0413992C0149931
Diseaseacylcarnitine measurement

SOX5 ZNF521 PPP1R3A SLC22A16

8.98e-04127994EFO_0005059
Diseasealcohol consumption measurement

SOX5 TOPAZ1 ZNF521 ALMS1 KCNC2 RABGAP1L RPRD2 MGA MAP2K5 TET3 AFF4 NPAS2

9.26e-0412429912EFO_0007878
DiseaseAlzheimer's disease (implicated_via_orthology)

SOX5 HIVEP2 LRP1

9.40e-0457993DOID:10652 (implicated_via_orthology)
DiseaseAnilide use measurement

RABGAP1L LRP1

1.14e-0315992EFO_0009938
Diseasehepatoblastoma (is_marker_for)

SALL4 SALL1

1.14e-0315992DOID:687 (is_marker_for)
Disease3-hydroxypropylmercapturic acid measurement

UBAP2 TOPAZ1 TXNDC11 STK10 PLEKHA5 NPAS2

1.22e-03352996EFO_0007014
Diseaseopioid dependence

MYO6 TACC2 TBX18 KCNC2 WDR72

1.24e-03237995EFO_0005611
Diseasecolorectal mucinous adenocarcinoma

SOX5 SLC22A16

1.30e-0316992EFO_0009361
DiseasePolyposis, Adenomatous Intestinal

F5 GREM1

1.30e-0316992C2713442
DiseaseFamilial Intestinal Polyposis

F5 GREM1

1.30e-0316992C2713443
Diseasecarcinoma (implicated_via_orthology)

SALL4 SALL1 HCK

1.32e-0364993DOID:305 (implicated_via_orthology)
Diseaseeosinophil count

HBS1L HIVEP2 RBBP8 MYT1 SIPA1L3 HECTD4 LMBRD2 TXNDC11 PPP1R3A BPTF TBC1D4 SALL1 TET3

1.41e-0314889913EFO_0004842
DiseaseLimb Deformities, Congenital

SALL4 SALL1

1.47e-0317992C0206762
DiseaseAdenomatous Polyposis Coli

F5 GREM1

1.47e-0317992C0032580
Diseasereaction time measurement

SOX5 TOPAZ1 HECTD4 ZNF521 AMBRA1 TACC2 KCNC2 RABGAP1L

1.69e-03658998EFO_0008393
Diseaseblood metabolite measurement

ALMS1 SLC22A16

1.84e-0319992EFO_0005664
Diseaseage at first sexual intercourse measurement

SOX5 SYTL2 ZNF521 AMBRA1 BPTF PLEKHA5

1.87e-03383996EFO_0009749
DiseaseR-warfarin measurement

HIVEP2 SALL4 PPP1R3A TBX18 ARHGAP21

2.03e-03265995EFO_0803324
Diseasebreast carcinoma

RBBP8 MYT1 MBD1 TACC2 TASOR2 TGFBR2 TBX18 CEP120 TNS1 GAB1

2.24e-0310199910EFO_0000305
Diseasecystatin C measurement

HIVEP2 HECTD4 SALL1 ALMS1 LRP1 WDR72

2.38e-03402996EFO_0004617
DiseaseSeckel syndrome

CENPE RBBP8

2.46e-0322992C0265202
Diseaserenal system measurement, blood urea nitrogen measurement

HECTD4 WDR72

2.46e-0322992EFO_0004741, EFO_0004742
Diseasegoiter

INSR SALL1

2.69e-0323992EFO_0004283
Diseaselevel of Sphingomyelin (d40:2) in blood serum

MYT1 ANKRD17

2.69e-0323992OBA_2045181
Diseasereticulocyte measurement

HBS1L UBAP2 INSR HECTD4 ATXN1L GGT7 SLC22A16 PCDHGB4 TNS1 ARHGAP21

2.84e-0310539910EFO_0010700
Diseasevital capacity

HIVEP2 RBBP8 MYT1 ZBTB24 IFNGR1 TBX18 CEP120 RPRD2 SNAPC4 TNS1 GAB1

2.89e-0312369911EFO_0004312
Diseasepallidum volume

SYTL2 WDR72

3.18e-0325992EFO_0006933
Diseasemyeloproliferative disorder

HBS1L ZNF521

3.18e-0325992EFO_0004251

Protein segments in the cluster

PeptideGeneStartEntry
PSATQQEASGHPLKS

nan

121

Q6ZRG5
LQKHSTPHAAFQPNS

ACIN1

111

Q9UKV3
ESSSNPSNPETLHAK

APLF

346

Q8IW19
LHSEQNKSSPDPTST

VCAN

2491

P13611
VSKSSTHPQHNPNEN

RBBP8

206

Q99708
NNASSQKPTHSSCIP

BCORP1

41

Q8N888
HPETPKPSISSNNSN

CEACAM8

141

P31997
ITNHSDQPPQNFSAT

GPR34

26

Q9UPC5
IGPNDQKTPSQTAFH

ALMS1

2031

Q8TCU4
SNSPHGPSAKFLVQN

BRIX1

131

Q8TDN6
PEASDSQAAQKPQAH

ZNF436-AS1

96

Q8NC38
SHQPTPHSSENNSNL

AMBRA1

546

Q9C0C7
DSTPNHPSQTTPAQK

ANKRD12

151

Q6UB98
SSSAHSNQQQPPGSV

ANKRD17

2101

O75179
TQSACQNSVHPANKP

ANKRD17

2226

O75179
PSEAQPTHAQSSKPQ

BPTF

2436

Q12830
PTHAQSSKPQVAAQS

BPTF

2441

Q12830
EKSSPGHRATAPQTQ

EEF1D

116

P29692
VNPHKVSPASSVDSN

AFF4

481

Q9UHB7
ANHRSPKPSANSVTS

CACNB2

241

Q08289
TASKSANPPHTIQAS

HBS1L

211

Q9Y450
ANPPHTIQASEEQSS

HBS1L

216

Q9Y450
NSSELTSHQQAPPNT

PCDHGB4

791

Q9UN71
HQREPNSDIPKNSST

KIAA1107

1076

Q9UPP5
VFQNPDAHPANSSSA

NPAS2

711

Q99743
PESAGNKHSNSNSVD

NUP98

671

P52948
NDPSASEHTQFKNIP

KCNC2

411

Q96PR1
DKASPDQNASTHTPQ

CLINT1

296

Q14677
PDKAQHNDSEQTQSP

GREM1

36

O60565
HSSPENHNNAKEPDS

MGA

1271

Q8IWI9
TDCNDNVPSHKNPAS

GAB1

211

Q13480
NVPSHKNPASSQSKH

GAB1

216

Q13480
DQSDEAPKNPHCTSQ

LRP1

2886

Q07954
HSFNKAPSATSPSGQ

ATXN1L

196

P0C7T5
PSTDHSPFLKGNQNS

KDM5D

1496

Q9BY66
ATRTAQPDHTQAPTK

MBD1

426

Q9UIS9
TANHSAPSLENSVQP

GGT7

521

Q9UJ14
KVNTRAGPSQHSSPA

MAP2K5

121

Q13163
NSPVCHSKFQNTTSP

CSNKA2IP

336

A0A1B0GTH6
HVSTHSATAQPQNPD

ERGIC1

131

Q969X5
KQSHAASAAPQASSP

FUBP3

526

Q96I24
PNVNALTHENQTKPS

KCT2

66

Q8NC54
SPPFESEDSQKHNQS

INSR

686

P06213
ASQHLATESPDSPNK

HECTD4

3771

Q9Y4D8
NSLKPEQASPSAHSH

SMPD4

381

Q9NXE4
HSFGDIPASQTNKPS

RABGAP1L

86

Q5R372
TNRAPQNSSPFSKHH

PPP1R3A

906

Q16821
TPQEKNSSPSSHSQE

BTBD18

216

B2RXH4
NSSPSSHSQEPRENK

BTBD18

221

B2RXH4
TSTIKPGPNSHNSNT

HCK

56

P08631
QPKSSSTNPSQAKAH

CARD6

1011

Q9BX69
AQRQASGDTPTTPKH

CABIN1

1916

Q9Y6J0
VPSHNQSPPTKDDAT

CEP120

386

Q8N960
NSSSVFQPNPDNHSV

GJA9

301

P57773
SPKTPNNFDHAQSCQ

ARFGEF3

1676

Q5TH69
QEQSQHPKPSEASTT

PYHIN1

416

Q6K0P9
TSPENAGPQNTKSEH

DLGAP5

661

Q15398
KPQHTFSDSQSPAES

CRYBG1

446

Q9Y4K1
PSKNDSFFTPDSNHN

RPRD2

931

Q5VT52
PSNSTQEFHKSPSIE

SALL1

931

Q9NSC2
QAKLPHANIPSATSS

SALL4

291

Q9UJQ4
PTTQDNKNPHVTSRA

CENPE

2361

Q02224
SHSSLSDSEFPPNNK

IFNGR1

421

P15260
PFNSSKLPEGHSSQQ

SYTL2

161

Q9HCH5
NGQPSKPDTSDHQVS

RELL2

281

Q8NC24
RKAQADSSTPTPHNA

SFSWAP

331

Q12872
QSRGQEPQAPSSSKH

PPP1R12C

326

Q9BZL4
LAEPQKAPSHQQATT

F5

791

P12259
KAPSHQQATTAGSPL

F5

796

P12259
HAAANSSPPENSNIT

LMBRD2

66

Q68DH5
PSDFQHKITVQASPN

MAP3K21

516

Q5TCX8
QGPVSNSPTEVQKHN

SLC22A16

331

Q86VW1
HSNPSPSQDTDGTKA

SIPA1L3

96

O60292
ASTIPPHVQKSVNND

TGFBR2

21

P37173
PSSQNAHSVPLDKAS

SPATA31E1

461

Q6ZUB1
SEAQQPASHPVASNQ

CIC

56

Q96RK0
TTNTKEPQGLPDHNS

C12orf56

221

Q8IXR9
LQKPVPHSQASEANS

UBAP2

296

Q5T6F2
EPSEQKSTVHLNPNS

ZNF804B

391

A4D1E1
HPSSNKDPTQGQKSA

ZSCAN32

11

Q9NX65
QPEEPTFKGSQSSHQ

ZSCAN32

156

Q9NX65
KSPSAIPEQNHSLND

RLF

631

Q13129
SAQAQAHTSAPTPAQ

SPEM3

261

A0A1B0GUW6
QNPSPSQDFGLHKNS

SPEM3

736

A0A1B0GUW6
STHQQSASASVPKNP

REV1

1046

Q9UBZ9
SPSEASQHSMQSPQK

SCML2

256

Q9UQR0
QQQHKVSPASESPFS

SYBU

36

Q9NX95
PSPSSNAFATNQTHQ

TBX18

501

O95935
SHQQPESCNHSNSPS

ZNF521

331

Q96K83
PDDTTNHSNSSKEVP

ZNF410

56

Q86VK4
TLENHTQNSSEVSPP

STK10

336

O94804
SVHPNLPSDKSQDAT

SORBS1

136

Q9BX66
NKAPSANVPQSSAIS

SORBS1

626

Q9BX66
NQDFHSKSPASSSLP

TNS1

806

Q9HBL0
PVSPVKHDSNSNSAN

WDR72

1051

Q3MJ13
KPATGQPNSSSHSAN

ZNF646

796

O15015
SEKHLQPSQAQPETS

TACC2

826

O95359
APVHTNKEDPATQTN

TMEM165

76

Q9HC07
APTPSSEPDTHQKAQ

TET3

511

O43151
SAPSHVQPSDSEKNR

TBC1D4

341

O60343
SQPEQSSPESALTHQ

ZSCAN4

276

Q8NAM6
GSHEKKPSSNPNQDD

nan

451

Q3C1V9
KPSSNPNQDDFHSSE

nan

456

Q3C1V9
TDFQNNHSSPKPTTL

ZBTB24

126

O43167
HHSDPASSPQNVANS

TXNDC11

796

Q6PKC3
SEPAKPAHSQNQSNF

TJP1

1381

Q07157
PSFTKQGNNSKPSNH

TOPAZ1

771

Q8N9V7
HAKTSAPHAQNPDVS

ZNF236

416

Q9UL36
FPNVPAQEASKSASH

SNAPC4

846

Q5SXM2
FAPHNSSTSPQKAEE

SOX5

101

P35711
QHSASSANVFPKESP

TASOR2

1996

Q5VWN6
FSPQDETQTANHKPE

PLEKHA5

1036

Q9HAU0
PNPSLNTKADDSHTV

HIVEP2

351

P31629
AANAQPHKLSETPGS

ARHGAP21

1936

Q5T5U3
PQPSDQHFTSAVHQK

MYO6

536

Q9UM54
SHEKQQPQTGDPSKS

MYT1

521

Q01538
AAAEHGQKPQTPSAS

NEXN-AS1

141

Q8NBZ9