Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionrRNA (cytosine-C5-)-methyltransferase activity

NSUN5 NSUN5P2

5.85e-054632GO:0009383
GeneOntologyMolecularFunctionzinc ion binding

TET2 TRAF4 ZACN ZIM2 ZNF407 SAMHD1 ZMYM1 ZNF385C ZFPM2 PRDM2 APOBEC3A

9.63e-058916311GO:0008270
GeneOntologyMolecularFunctionrRNA (cytosine) methyltransferase activity

NSUN5 NSUN5P2

1.46e-046632GO:0016434
GeneOntologyMolecularFunctiondisaccharide binding

LGALS1 LGALS9

2.04e-047632GO:0048030
GeneOntologyMolecularFunctiongalactose binding

LGALS1 LGALS9

2.04e-047632GO:0005534
GeneOntologyMolecularFunctionC-methyltransferase activity

NSUN5 NSUN5P2

2.71e-048632GO:0008169
GeneOntologyMolecularFunctiontransition metal ion binding

TET2 TRAF4 ZACN ZIM2 ZNF407 SAMHD1 ZMYM1 ZNF385C F8 ZFPM2 PRDM2 APOBEC3A

2.97e-0411896312GO:0046914
GeneOntologyMolecularFunctionRNA methyltransferase activity

NSUN5P1 NSUN5 NSUN5P2

1.24e-0367633GO:0008173
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS1 LGALS9

1.79e-0320632GO:0070492
GeneOntologyMolecularFunctionrRNA methyltransferase activity

NSUN5 NSUN5P2

2.59e-0324632GO:0008649
GeneOntologyMolecularFunctioncatalytic activity, acting on a rRNA

NSUN5 NSUN5P2

2.80e-0325632GO:0140102
GeneOntologyBiologicalProcessrRNA base methylation

NSUN5P1 NSUN5 NSUN5P2

4.19e-0611623GO:0070475
DomainZnf_C2H2-like

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 RNF138 ZFPM2 PRDM2 ZNF461 ZNF445

2.69e-047966210IPR015880
DomainZnf_C2H2

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 RNF138 ZFPM2 PRDM2 ZNF461 ZNF445

2.94e-048056210IPR007087
DomainMeTrfase_RsmB/NOP2

NSUN5 NSUN5P2

3.00e-048622IPR001678
DomainMethyltr_RsmB-F

NSUN5 NSUN5P2

3.00e-048622PF01189
DomainZnF_C2H2

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 RNF138 ZFPM2 PRDM2 ZNF461 ZNF445

3.03e-048086210SM00355
Domain-

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 ZFPM2 PRDM2 ZNF461 ZNF445

3.81e-046796293.30.160.60
Domainzf-C2H2

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 ZFPM2 PRDM2 ZNF461 ZNF445

4.42e-04693629PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 ZFPM2 PRDM2 ZNF461 ZNF445

4.46e-04694629IPR013087
Domain-

NRDE2 RAPSN NAPA ANAPC5 GTF3C3

6.17e-042076251.25.40.10
Domain-

CORO2B FBXW9 BBS2 WDR90 DCAF5 PLXNB3

8.15e-043336262.130.10.10
DomainWD40/YVTN_repeat-like_dom

CORO2B FBXW9 BBS2 WDR90 DCAF5 PLXNB3

8.41e-04335626IPR015943
DomainZINC_FINGER_C2H2_2

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 ZFPM2 PRDM2 ZNF461 ZNF445

9.83e-04775629PS50157
DomainZINC_FINGER_C2H2_1

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 ZFPM2 PRDM2 ZNF461 ZNF445

1.00e-03777629PS00028
DomainTPR-like_helical_dom

NRDE2 RAPSN NAPA ANAPC5 GTF3C3

1.05e-03233625IPR011990
DomainGal-bind_lectin

LGALS1 LGALS9

1.11e-0315622PF00337
DomainGal-bind_lectin

LGALS1 LGALS9

1.11e-0315622SM00908
DomainGALECTIN

LGALS1 LGALS9

1.11e-0315622PS51304
DomainGalectin_CRD

LGALS1 LGALS9

1.11e-0315622IPR001079
DomainGLECT

LGALS1 LGALS9

1.11e-0315622SM00276
DomainWD40_repeat_dom

CORO2B FBXW9 BBS2 WDR90 DCAF5

3.04e-03297625IPR017986
Domainzf-C2H2_6

ZFP14 ZNF880 PRDM2 ZNF461 ZNF445

3.85e-03314625PF13912
DomainKRAB

ZIM2 ZFP14 ZNF880 ZNF461 ZNF445

6.66e-03358625PS50805
DomainKRAB

ZIM2 ZFP14 ZNF880 ZNF461 ZNF445

6.66e-03358625PF01352
DomainKRAB

ZIM2 ZFP14 ZNF880 ZNF461 ZNF445

7.55e-03369625SM00349
DomainKRAB

ZIM2 ZFP14 ZNF880 ZNF461 ZNF445

7.63e-03370625IPR001909
DomainTPR

RAPSN ANAPC5 GTF3C3

9.05e-03129623SM00028
DomainTPR_repeat

RAPSN ANAPC5 GTF3C3

9.83e-03133623IPR019734
Pubmed

Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome.

NSUN5P1 NSUN5 NSUN5P2

2.49e-08465311978965
Pubmed

Identification of additional transcripts in the Williams-Beuren syndrome critical region.

NSUN5P1 NSUN5 NSUN5P2

1.02e-061165312073013
Pubmed

Galectin-1 and -9 in angiogenesis: a sweet couple.

LGALS1 LGALS9

3.44e-06265224861051
Pubmed

Cognitive deficits in mice lacking Nsun5, a cytosine-5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells.

NSUN5 NSUN5P2

3.44e-06265230485550
Pubmed

The Significance of Galectin-1 and Galectin-9 Expression in Endometrial Carcinoma.

LGALS1 LGALS9

3.44e-06265231487707
Pubmed

Galectin expression profiling identifies galectin-1 and Galectin-9Δ5 as prognostic factors in stage I/II non-small cell lung cancer.

LGALS1 LGALS9

3.44e-06265225259711
Pubmed

Mice with NOP2/sun RNA methyltransferase 5 deficiency die before reaching puberty due to fatal kidney damage.

NSUN5 NSUN5P2

3.44e-06265238712768
Pubmed

Characterisation of endogenous Galectin-1 and -9 expression in monocyte and macrophage subsets under resting and inflammatory conditions.

LGALS1 LGALS9

3.44e-06265232771893
Pubmed

Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.

NSUN5 NSUN5P2

3.44e-06265231722427
Pubmed

Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients.

LGALS1 LGALS9

3.44e-06265223121677
Pubmed

Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.

NSUN5 NSUN5P2

3.44e-06265231174389
Pubmed

NSUN5 is essential for proper cell proliferation and differentiation of mouse preimplantation embryos.

NSUN5 NSUN5P2

3.44e-06265238670153
Pubmed

RNA-methyltransferase Nsun5 controls the maternal-to-zygotic transition by regulating maternal mRNA stability.

NSUN5 NSUN5P2

3.44e-06265236495115
Pubmed

Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways.

LGALS1 LGALS9

3.44e-06265218258591
Pubmed

Role of Galectins in Tumors and in Clinical Immunotherapy.

LGALS1 LGALS9

1.03e-05365229389859
Pubmed

Galectin-1 and Galectin-3 Constitute Novel-Binding Partners for Factor VIII.

F8 LGALS1

1.03e-05365227013611
Pubmed

Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke.

LGALS1 LGALS9

1.03e-05365228112232
Pubmed

NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor.

NSUN5 NSUN5P2

1.03e-05365233177158
Pubmed

Evaluation of the immunohistochemical expression of Gal-1, Gal-3 and Gal-9 in the colon of chronic chagasic patients.

LGALS1 LGALS9

1.03e-05365228554765
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS1 LGALS9

2.06e-05465230120235
Pubmed

A galectin-specific signature in the gut delineates Crohn's disease and ulcerative colitis from other human inflammatory intestinal disorders.

LGALS1 LGALS9

2.06e-05465226891020
Pubmed

Chemokines modulate glycan binding and the immunoregulatory activity of galectins.

LGALS1 LGALS9

2.06e-05465234931005
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS1 LGALS9

3.43e-0556529566950
Pubmed

Galectin-9 induces maturation of human monocyte-derived dendritic cells.

LGALS1 LGALS9

3.43e-05565216116184
Pubmed

Galectins in mouse embryogenesis.

LGALS1 LGALS9

5.13e-0566528674632
Pubmed

Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation.

NSUN5 NSUN5P2

7.18e-05765233968922
Pubmed

Role of galectin-1 in the developing mouse olfactory system.

LGALS1 LGALS9

7.18e-0576528873770
Pubmed

Expression of NOL1/NOP2/sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis.

NSUN5 NSUN5P2

7.18e-05765223816522
Pubmed

Mammalian galectins bind galactoseβ1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.

LGALS1 LGALS9

9.56e-05865223751344
Pubmed

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry.

LGALS1 LGALS9

1.23e-04965221670307
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

UBA1 MGST3 SAMM50 ZMYM1 ATL2 ANAPC5 GTF3C3 LGALS1 PPP1CB

2.86e-04115565920360068
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

MYO1G USP34 UBA1 INTS1 PEAK1

3.46e-0432265526514267
Pubmed

Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex.

NSUN5 NSUN5P2

3.56e-041565231462248
Pubmed

Genetically distinct subsets within ANCA-associated vasculitis.

WNT9B F8

5.16e-041865222808956
Pubmed

The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.

ANAPC5 GTF3C3 PPP1CB

5.33e-048465326299517
Pubmed

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.

WDR90 F8

6.39e-042065223446634
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

UBA1 INTS1 ANAPC5 GTF3C3 PPP1CB

8.60e-0439465527248496
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

NSUN5 VPS13D NLRX1 SAMM50 DCAF5 PPP1CB

9.44e-0460665636538041
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

ZNF335 ZMYM1 LGALS1

1.17e-0311065326841866
Pubmed

High-throughput mapping of a dynamic signaling network in mammalian cells.

RAPSN ANAPC5 RNF138 PPP1CB

1.44e-0326065415761153
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

USP34 NRDE2 NLRX1 INTS1 ANAPC5 LGALS1 PPP1CB

1.53e-0391065736736316
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

TET2 INTS1 RXFP1 GTF3C3

1.70e-0327265431010829
Pubmed

A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.

LGALS1 LGALS9

1.75e-033365223118208
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

USP34 MGST3 INTS1 ZNF407 ZMYM1 ATL2 GTF3C3 LGALS1

1.76e-03120365829180619
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

MTRF1 BBS2 RXFP1 LIPI APOBEC3A ZNF461

1.77e-0368665629987050
Cytoband7q11.23

NSUN5P1 NSUN5 NSUN5P2

3.63e-04976537q11.23
CytobandEnsembl 112 genes in cytogenetic band chr7p22

AP5Z1 INTS1 RNF216P1

9.30e-04134653chr7p22
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF335 ZIM2 ZNF407 ZFP14 ZNF880 ZFPM2 ZNF461 ZNF445

3.48e-0471845828
GeneFamilyGalectins

LGALS1 LGALS9

6.23e-0415452629
GeneFamilyWD repeat domain containing

CORO2B FBXW9 WDR90 DCAF5

4.03e-03262454362
ToppCellMild/Remission-B_memory-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYO1G TRAF4 CHAD SAMHD1 PAQR7

6.08e-061776558f2ce5ffc94ca90412cb6899629f322dc778215c
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 APOBEC3A LGALS9

9.96e-0619665589ff93cbfbe39fbdf2498e8fdc5d61a0ecb26fc9
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 APOBEC3A LGALS9

9.96e-0619665509574bfeb1d3da53b5471cfb0602946d328b3b5c
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G MGST3 SAMHD1 LGALS1 LGALS9

1.02e-051976559c8c1ce8ed69b3c2b12ecca349ac1901f66b46ab
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 USP34 SAMHD1 PRDM2 APOBEC3A

1.10e-0520065512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF335 ZFP14 ZNF880 CCDC191

4.69e-05136654edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF335 ZFP14 ZNF880 CCDC191

4.69e-0513665403e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 RXFP1 LIPI ZFPM2

6.01e-05145654051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1G NSUN5 WDR90 LGALS1

9.46e-051636549c91415a56b12b3b2d15d253bb59db8bedf49ea2
ToppCellsevere-unassigned|severe / disease stage, cell group and cell class

AP5Z1 ZMYM1 INO80D ITPRIPL1

9.92e-05165654f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCellMild/Remission-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TRAF4 CHAD SAMHD1 PAQR7

1.02e-0416665403e1a369d8a83b814def07e29cabb023226b4828
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SAMHD1 LIPI ZFPM2

1.11e-04170654fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RAB36 FBXW9 WDR90 ZFPM2

1.11e-04170654f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SAMHD1 LIPI ZFPM2

1.11e-0417065403044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN2 RXFP1 F8 ZFPM2

1.30e-0417765416197068260fc062bf8b730a51a199887ea580b9
ToppCellwk_08-11-Epithelial-PNS-Late_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RAPSN CHAD SAMHD1 PLXNB3

1.33e-04178654a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCellmetastatic_Brain-Myeloid_cells-Pleural_Mac|metastatic_Brain / Location, Cell class and cell subclass

SAMHD1 LGALS1 APOBEC3A LGALS9

1.39e-041806547de1c8ab1152fa517c6b4830d93ff53a19fca3d7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SAMHD1 RXFP1 ZFPM2

1.45e-0418265444764676ed3f51ba171ce63f669390392fa50a43
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZIM2 CHAD ATL2 ZFPM2

1.45e-0418265403a5a02acd48f0eb210485348bfe0cd21f486215
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 SAMHD1 RXFP1 ZFPM2

1.45e-04182654d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B MMRN2 F8 ZFPM2

1.57e-041866542cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSTM1 ZMYM1 PEAK1 F8

1.57e-0418665437860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B MMRN2 F8 ZFPM2

1.57e-0418665490d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSTM1 ZMYM1 PEAK1 F8

1.57e-0418665460830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSTM1 ZMYM1 PEAK1 F8

1.57e-04186654baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

WNT9B MMRN2 INO80D F8

1.60e-041876547876dcb4800c2e54874df3d933efb79307a64a97
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 ZNF407 INO80D PRDM2

1.64e-04188654ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G NAPA LGALS1 LGALS9

1.64e-0418865459d5c7b147af118442adadf708ce2d1422b1e9aa
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_macrophage|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G NAPA LGALS1 LGALS9

1.64e-041886542e268d8091e25d50bf05f26517d3ceb583801fd4
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2B MMRN2 F8 ZFPM2

1.67e-04189654ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGST3 SAMHD1 LGALS1 LGALS9

1.78e-04192654fb0d05a2c83816794652a6e5af8713e9bb22d5db
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_follicular_helper_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRAF4 NAPA RNF138 PPP1CB

1.78e-041926543e2a0f332e7f9833ba88f3c809cee78b65090401
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

GPR180 RXFP1 APOBEC3A LGALS9

1.78e-041926541a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCellNS-critical-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SAMHD1 LGALS1 APOBEC3A LGALS9

1.81e-041936540dd83b21e164147abfd511a927615c40a28781a2
ToppCellEndothelial-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

WNT9B MMRN2 RXFP1 F8

1.85e-04194654abea887dd472c1a0d572e690bc8914c1b94712ad
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

TET2 NAPA SAMHD1 APOBEC3A

1.85e-04194654d1366b169d14011194e61d16b6b0953349febc78
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGST3 SAMHD1 LGALS1 LGALS9

1.85e-04194654412c2b8eb522da6c84f8b00d32d6f0bee555251f
ToppCellEndothelial-endothelial_cell_of_vein|World / Lineage, Cell type, age group and donor

WNT9B MMRN2 RXFP1 ZFPM2

1.85e-041946543cbd9622a68e89add90e589867d88c83c5a33476
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 APOBEC3A

1.88e-04195654f8908657db50f1c58904dd6fee4fc23f5ae3eed6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Neutrophil|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G SAMHD1 LGALS1 LGALS9

1.88e-04195654d8d2467196d7b2ce0c2cf6782e03e6db141ed3bf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G CMA1 SAMHD1 LGALS1

1.88e-04195654391d8e00dd5f988baa6dbda8414d3c020679ea2f
ToppCellCTRL|World / Disease state, Lineage and Cell class

MGST3 SAMHD1 LGALS1 LGALS9

1.88e-04195654cad77cdc6e0aa0875eff5ecd3805a6cf056d729d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G SAMHD1 LGALS1 LGALS9

1.88e-0419565468b579258caf023570c3922269e831e27d847934
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO1G TET2 SAMHD1 LGALS1

1.92e-041966547dff78ff7b2b333680de1c9ca78190770574d796
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 APOBEC3A

1.92e-04196654894f9943404cf252dbdf9e5769d9238f982ba8b8
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGST3 SAMHD1 LGALS1 LGALS9

1.96e-04197654bf0f64bd356584cd4f8ac68867604c2118067450
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 APOBEC3A

1.96e-041976547870c0651caefb0ed13d9f9dab43b5f24d6a9efc
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 LGALS9

2.00e-0419865474591eba5dbb2d77d416309326a26be969e4ad42
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage|367C / Donor, Lineage, Cell class and subclass (all cells)

MGST3 SAMHD1 LGALS1 LGALS9

2.00e-041986541771c282cd6422c35a4131c827d7daedfd6e7541
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 LGALS9

2.00e-04198654f3346c26b9647a199faf3cd7ab19c3a963dbabc2
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYO1G SAMHD1 LGALS1 LGALS9

2.00e-041986543e1e79bb7b13540a06956b59c6a62984efea19ee
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMRN2 RXFP1 F8 DISP1

2.00e-041986542400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCellNS-critical-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MGST3 SAMHD1 LGALS1 LGALS9

2.00e-0419865449fc6ba574ed5c848eaa329aad1d5c8091c79f47
ToppCellBLOOD--(3)_Intermediate_monocytes| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SAMHD1 LGALS1 APOBEC3A LGALS9

2.00e-0419865461685a86f70a7d2a6d3260b76081119978c15661
ToppCell(6)_Endothelial-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MMRN2 RXFP1 F8 DISP1

2.00e-04198654a5e1b321376caf262ea48904d31afd1b8e9d3be2
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGST3 SAMHD1 LGALS1 LGALS9

2.04e-0419965494308fa48d73bedbfaf0e68570e151af26563b01
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G SAMHD1 LGALS1 LGALS9

2.04e-0419965487c7b8c77c28f3cfa6d6dddfd00c9d18d116207e
ToppCellICU-NoSEP-Myeloid|ICU-NoSEP / Disease, Lineage and Cell Type

SAMHD1 LGALS1 APOBEC3A LGALS9

2.04e-041996547ed8209dc4cb198e2ff6e00d941a4df64849b9a4
ToppCellBronchial-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYO1G TET2 LGALS1 APOBEC3A

2.08e-042006541aa4197f1c7c099313dc2e1f8b1153252add7a33
ToppCellSepsis-ICU-NoSEP-Myeloid|ICU-NoSEP / Disease, condition lineage and cell class

SAMHD1 LGALS1 APOBEC3A LGALS9

2.08e-042006549fc8b8f16421b5d47e9d0e6d70d59208de5e5290
Drugsplitomicin; Up 200; 20uM; PC3; HG-U133A

ADAMTS12 TRAF4 VPS13D ZNF335 ZIM2 SAMHD1 ZMYM1

1.34e-06194657661_UP
DiseaseWilliams-Beuren syndrome (implicated_via_orthology)

NSUN5P1 NSUN5 NSUN5P2

3.57e-0615603DOID:1928 (implicated_via_orthology)
DiseaseNephritis

LGALS1 LGALS9

1.45e-049602C0027697
Diseasemetabolite measurement, diet measurement

RAPSN ZNF335 SAMM50

4.14e-0471603EFO_0004725, EFO_0008111
Diseasediacylglycerol 38:5 measurement

RAPSN SAMM50

6.80e-0419602EFO_0020067
Diseasemyelodysplastic syndrome (is_implicated_in)

TET2 ZFPM2

1.71e-0330602DOID:0050908 (is_implicated_in)
Diseasegranulocyte count

MYO1G TET2 RAPSN MGST3

1.79e-03254604EFO_0007987
Diseaseimmature platelet measurement

MYO1G DCAF5 ZFPM2

1.85e-03119603EFO_0803541
DiseaseGlobal developmental delay

ZNF335 INTS1 GTF3C3

2.54e-03133603C0557874
Diseasetriglyceride measurement, C-reactive protein measurement

RAPSN ZNF335

2.73e-0338602EFO_0004458, EFO_0004530
DiseaseAutoimmune Diseases

RAPSN F8

3.32e-0342602C0004364

Protein segments in the cluster

PeptideGeneStartEntry
ICHLRFNSANQAEAH

ZNF385C

81

Q66K41
HRGFLHNQAKNLLCG

APOBEC3A

51

P31941
IQFCRDNLHLFSGHL

AP5Z1

411

O43299
HLQHCQIREVAAGAF

CHAD

81

O15335
LEQHTVCHFFSLNQR

DISP1

1256

Q96F81
DHRNLRPFHCQFLAG

ADAMTS12

1396

P58397
IHLNNFHCHRGQDFV

RNF216P1

11

Q6NUR6
PCSHIFHLRCLQNNG

RAPSN

381

Q13702
CLQLREHFHGQVSAA

RAB36

96

O95755
LHALAGFQQRALCHA

NSUN5

331

Q96P11
NLAALHCRFGHYQQA

ANAPC5

306

Q9UJX4
HCRFGHYQQAELALQ

ANAPC5

311

Q9UJX4
GLLHVFANRNGCFQL

FBXW9

366

Q5XUX1
FGQGHQLFHIFLVLC

PAQR7

271

Q86WK9
NLCLHFNPRFNAHGD

LGALS1

41

P09382
FQEFRQQNHLSCFLH

INTS1

1896

Q8N201
QQNHLSCFLHVLGLL

INTS1

1901

Q8N201
QHQRLFHSLFGNFQG

MMRN2

746

Q9H8L6
AQRFHINLCSGNHIA

LGALS9

251

O00182
NHCHFGFQTQRELLQ

ZFPM2

366

Q8WW38
RNLQHFRGLPASFHC

PLXNB3

706

Q9ULL4
IFRLHFCGPNIINHF

OR5A1

166

Q8NGJ0
LAVHFNIQQDCGHFL

PEAK1

1381

Q9H792
RLHALAGFQQRALCH

NSUN5P2

146

Q63ZY6
ALFLQQCHFLRQAGH

NRDE2

471

Q9H7Z3
LKGEHHSNIFCLAFN

DCAF5

96

Q96JK2
DLGQFLLFCHISSHQ

F8

321

P00451
EFHGDHALLCVRINN

GPR180

46

Q86V85
GHIFNCIQRAHQNTL

MGST3

51

O14880
HALAGFQQRALCHAL

NSUN5P1

66

Q3KNT7
RNLEGHHQIAAACFL

NLRX1

356

Q86UT6
LSLRLHFCGANVINH

OR13H1

161

Q8NG92
NLFNHTLTCFEHNLQ

OSTM1

191

Q86WC4
NFFLLRGNHECASIN

PPP1CB

116

P62140
QQRSLHHFLIGNNFL

ITPRIPL1

486

Q6GPH6
FQVCFTSLRNGGHLH

BBS2

531

Q9BXC9
HDNHFCAVNTRFLAI

CORO2B

41

Q9UQ03
PLCLGHFHNRHVFQQ

CCDC191

546

Q8NCU4
RKHIHNCFSNLGCFL

ATL2

281

Q8NHH9
HCFQHILLNHSQQLF

INO80D

466

Q53TQ3
FRTHFFLNAGNLCNL

SAMM50

391

Q9Y512
AFLCNLQQHQRDLHP

PRDM2

1201

Q13029
FARDCHHLGIQNNFD

SAMHD1

316

Q9Y3Z3
IQFIKCNHQRAVHLF

LIPI

246

Q6XZB0
RLLDHCNSNHLFQIV

RNF138

171

Q8WVD3
AGNAFCQAAQLHLQL

NAPA

61

P54920
NGYLQCHIQLHSHQF

MTRF1

16

O75570
ENHALCVLNGHNAFV

GTF3C3

731

Q9Y5Q9
SHFRDFDHNLQLCVG

CMA1

176

P23946
SCDNFNLLHPIFQRH

UHRF1BP1L

646

A0JNW5
QDFAGHDNAVHLCRF

WDR90

1711

Q96KV7
CGKVFNRNAHLARHQ

ZNF880

301

Q6PDB4
GNHIHNLRNLTFISC

RXFP1

256

Q9HBX9
LRHLQGHLNTCSFNV

TRAF4

96

Q9BUZ4
IGFQALHQFCAQHGR

UBA1

331

P22314
QCGKAFLQNVHLLQH

ZIM2

416

Q9NZV7
NCNFELLHFPRDHSN

ZACN

156

Q401N2
QCGKAFRNHSFLLIH

ZNF445

766

P59923
CGKAFRVHQQLARHQ

ZFP14

261

Q9HCL3
NFVSLGCLFIQHGLH

ZMYM1

1046

Q5SVZ6
ICHFATAQLGDARNH

ZNF407

1571

Q9C0G0
NELFNCRQFIGPQHH

USP34

736

Q70CQ2
AAHLGLLECQFQFRH

WNT9B

81

O14905
AHVQSLCGTRFHFQQ

TET2

671

Q6N021
HLCGQRFNRNGHLKF

ZNF335

1106

Q9H4Z2
AFCDGLQLTLHQRIH

ZNF461

421

Q8TAF7
QCGKAFNHRLQLNLH

ZNF461

526

Q8TAF7
FESLHRGQAFHILNN

VPS13D

1476

Q5THJ4
NHCRHQVAYLGLLEN

MYO1G

616

B0I1T2