Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF3398

DOCK10 DOCK9

3.98e-056312PF11878
DomainDOCK_C/D_N

DOCK10 DOCK9

3.98e-056312IPR021816
DomainDOCK_C

DOCK10 DOCK9

1.45e-0411312IPR010703
DomainDHR-1_domain

DOCK10 DOCK9

1.45e-0411312IPR027007
DomainDHR_2

DOCK10 DOCK9

1.45e-0411312PS51651
DomainDHR_1

DOCK10 DOCK9

1.45e-0411312PS51650
DomainDOCK-C2

DOCK10 DOCK9

1.45e-0411312PF14429
DomainDHR-2

DOCK10 DOCK9

1.45e-0411312IPR027357
DomainDHR-2

DOCK10 DOCK9

1.45e-0411312PF06920
DomainDOCK

DOCK10 DOCK9

1.45e-0411312IPR026791
DomainVitD_rcpt

NR1I2 VDR

2.40e-0414312IPR000324
DomainPAS_fold_3

NPAS3 HIF1A

6.60e-0423312IPR013655
DomainPAS_3

NPAS3 HIF1A

6.60e-0423312PF08447
DomainPAS-assoc_C

NPAS3 HIF1A

7.19e-0424312IPR000700
DomainPAS

NPAS3 HIF1A

7.81e-0425312PF00989
DomainPAS_fold

NPAS3 HIF1A

7.81e-0425312IPR013767
DomainHLH

NPAS3 HIF1A ASCL1

8.13e-04111313PF00010
DomainPAC

NPAS3 HIF1A

8.45e-0426312SM00086
DomainPAC

NPAS3 HIF1A

8.45e-0426312PS50113
DomainPAC

NPAS3 HIF1A

8.45e-0426312IPR001610
DomainHLH

NPAS3 HIF1A ASCL1

9.24e-04116313SM00353
DomainBHLH

NPAS3 HIF1A ASCL1

9.48e-04117313PS50888
DomainbHLH_dom

NPAS3 HIF1A ASCL1

9.71e-04118313IPR011598
DomainPAS

NPAS3 HIF1A

1.28e-0332312SM00091
DomainPAS

NPAS3 HIF1A

1.45e-0334312IPR000014
DomainPAS

NPAS3 HIF1A

1.45e-0334312PS50112
Domainzf-C4

NR1I2 VDR

2.64e-0346312PF00105
DomainNUCLEAR_REC_DBD_1

NR1I2 VDR

2.64e-0346312PS00031
DomainZnf_hrmn_rcpt

NR1I2 VDR

2.64e-0346312IPR001628
DomainNuclear_hrmn_rcpt

NR1I2 VDR

2.64e-0346312IPR001723
DomainZnF_C4

NR1I2 VDR

2.64e-0346312SM00399
DomainNUCLEAR_REC_DBD_2

NR1I2 VDR

2.64e-0346312PS51030
Domain-

NR1I2 VDR

2.75e-03473121.10.565.10
DomainHOLI

NR1I2 VDR

2.87e-0348312SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR1I2 VDR

2.87e-0348312IPR000536
DomainHormone_recep

NR1I2 VDR

2.87e-0348312PF00104
Domain-

NR1I2 VDR

4.02e-03573123.30.50.10
DomainZnf_NHR/GATA

NR1I2 VDR

4.16e-0358312IPR013088
DomainPH

DOCK10 PHLDB1 DOCK9

6.35e-03229313PF00169
DomainPH

DOCK10 PHLDB1 DOCK9

1.08e-02278313SM00233
DomainPH_DOMAIN

DOCK10 PHLDB1 DOCK9

1.09e-02279313PS50003
DomainPH_domain

DOCK10 PHLDB1 DOCK9

1.10e-02280313IPR001849
PathwayWP_EFFECT_OF_INTESTINAL_MICROBIOME_ON_ANTICOAGULANT_RESPONSE_OF_VITAMIN_K_ANTAGONISTS

NR1I2 VDR

6.47e-058222M45529
PathwayWP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY

NR1I2 VDR

3.12e-0417222M39666
PathwayBIOCARTA_TH1TH2_PATHWAY

NR1I2 IL2RA

5.77e-0423222M6705
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

NR1I2 VDR

8.57e-0428222MM15042
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

NR1I2 VDR

9.85e-0430222MM15866
PathwayPID_CDC42_REG_PATHWAY

DOCK10 DOCK9

9.85e-0430222M83
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

NR1I2 VDR

9.85e-0430222M27323
PathwayBIOCARTA_NUCLEARRS_PATHWAY

NR1I2 VDR

1.19e-0333222MM1448
PathwayBIOCARTA_NUCLEARRS_PATHWAY

NR1I2 VDR

1.27e-0334222M16393
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

NR1I2 VDR

1.34e-0335222M39488
PathwayWP_NUCLEAR_RECEPTORS

NR1I2 VDR

1.58e-0338222MM15865
PathwayWP_NUCLEAR_RECEPTORS

NR1I2 VDR

1.58e-0338222M39657
PathwayWP_GPCRS_ODORANT

TAS1R2 GPR87 GPR139

1.79e-03157223MM15872
Pubmed

FBXO30 functions as a tumor suppressor and an E3 ubiquitin ligase for hZIP1‑mediated HIF‑1α degradation in renal cell carcinoma.

HIF1A FBXO30

8.73e-07233236799168
Pubmed

RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated.

YTHDC2 HIF1A

8.73e-07233226996300
Pubmed

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia.

NR1I2 VDR

2.62e-06333216691293
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK10 DOCK9

2.62e-06333232241915
Pubmed

Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism.

HIF1A VDR

2.62e-06333233182300
Pubmed

Association of a single nucleotide polymorphism in the constitutive androstane receptor gene with bone mineral density.

NR1I2 VDR

2.62e-06333219702932
Pubmed

On the relationship between VDR, RORα and RORγ receptors expression and HIF1-α levels in human melanomas.

HIF1A VDR

5.23e-06433231287590
Pubmed

Involvement of suppressor for Gal 1 in the ubiquitin/proteasome-mediated degradation of estrogen receptors.

NR1I2 VDR

5.23e-06433214702340
Pubmed

Vitamin D promotes vascular regeneration.

HIF1A VDR

5.23e-06433225015343
Pubmed

Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR.

NR1I2 VDR

8.72e-06533215610065
Pubmed

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

DOCK10 DOCK9

8.72e-06533215710388
Pubmed

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

DOCK10 DOCK9

1.31e-05633225851601
Pubmed

ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1.

HIF1A ABL2

1.31e-05633237040401
Pubmed

The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease.

HIF1A MYH11

1.83e-05733234818545
Pubmed

Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors.

NR1I2 VDR

3.13e-05933211891224
Pubmed

Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket.

NR1I2 VDR

3.13e-05933220413580
Pubmed

Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.

NR1I2 VDR

3.13e-05933228751364
Pubmed

Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.

HIF1A ASCL1

3.91e-051033233053356
Pubmed

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.

NPAS3 IL2RA

3.91e-051033222228203
Pubmed

Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis.

NR1I2 VDR

4.78e-051133231875848
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK10 DOCK9

7.89e-051433212432077
Pubmed

Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.

NPAS3 HIF1A ASCL1

1.11e-049833318557763
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXE1 NPAS3 HIF1A NR1I2 ASCL1 VDR

1.89e-0490833619274049
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

MYH11 ASCL1

2.18e-042333219897741
Pubmed

The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.

YTHDC2 ABL2

2.58e-042533235874829
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

YTHDC2 PHLDB1 OTOF SVOP

3.68e-0436133426167880
Pubmed

Genome-wide association study of periodontal pathogen colonization.

OTOF CIB4

3.99e-043133222699663
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

DOCK10 PHLDB1 RP2 DOCK9

4.34e-0437733438117590
Pubmed

Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.

HIF1A ASCL1

4.53e-043333230037926
Pubmed

Control of endodermal endocrine development by Hes-1.

MYH11 ASCL1

4.81e-043433210615124
Pubmed

The genetic program of hematopoietic stem cells.

DOCK10 CD79B

6.01e-043833210834841
Pubmed

Transcriptional network orchestrating regional patterning of cortical progenitors.

NPAS3 ASCL1

6.33e-043933234921112
Pubmed

Olig3 regulates early cerebellar development.

HIF1A ASCL1

6.66e-044033233591268
Pubmed

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.

NPAS3 IL2RA

8.06e-044433223817569
Pubmed

Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.

HIF1A MYH11

9.19e-044733228527294
CytobandEnsembl 112 genes in cytogenetic band chr2p23

OTOF CIB4

5.17e-03149332chr2p23
CytobandEnsembl 112 genes in cytogenetic band chr1q25

RGSL1 ABL2

6.45e-03167332chr1q25
CytobandEnsembl 112 genes in cytogenetic band chr16p12

EEF2K GPR139

6.83e-03172332chr16p12
GeneFamilyBasic helix-loop-helix proteins

NPAS3 HIF1A ASCL1

3.55e-04110233420
GeneFamilyNuclear hormone receptors

NR1I2 VDR

1.76e-034923271
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK10 PHLDB1 DOCK9

2.18e-03206233682
GeneFamilyG protein-coupled receptors, Class A orphans

GPR87 GPR139

4.38e-0378232262
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#1_top-relative-expression-ranked_1000

CXorf58 YTHDC2 HIF1A FBXO30 PARP12

1.24e-05210315gudmap_developingGonad_e14.5_ ovary_1000_k1
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHLDB1 ABL2 IL2RA VDR

5.67e-06159334ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PHLDB1 ABL2 IL2RA VDR

5.67e-061593342f6c60ddff2208a68146f9786143d9aefd528840
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPAS3 NOL4 SVOP ASCL1

6.41e-06164334be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK10 NOL4 SVOP ASCL1

9.88e-061833349dfb398b9995d562864fe688861a831ada0814cd
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CD79B RP2 IL2RA VDR

9.88e-061833343cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 SVOP ASCL1

1.08e-0518733498477ba04a42a8da80a72f41a182429f46283595
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPAS3 NOL4 SVOP ASCL1

1.10e-05188334c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 SVOP ASCL1

1.15e-051903342375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 SVOP ASCL1

1.27e-051953345f33ece997f074598b4201ff74f592ee07c86a06
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HIF1A MYH11 SVOP SPDYE3

1.35e-05198334cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Thalamus / BrainAtlas - Mouse McCarroll V32

MYH11 IL2RA CIB4

3.17e-05833334017af9a4804a06d0f2cd0f285ebf1b582b751de
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Car4_(Mural.Rgs5Acta2.Car4)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYH11 IL2RA CIB4

3.17e-058333359fce941d45f9763a8584f3fd5b7c0738de9f592
ToppCellThalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Car4_(Mural.Rgs5Acta2.Car4)-|Thalamus / BrainAtlas - Mouse McCarroll V32

MYH11 IL2RA CIB4

3.17e-0583333ebabce70dc01fdeda7fccebc2c4a0b686cda580f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-8|TCGA-Lung / Sample_Type by Project: Shred V9

NOL4 SVOP GPR139

9.06e-05118333e3dca31f47324ee207b773145475147fe3e761fe
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 ASCL1 GPR139

1.10e-0412633361e599678680e5aa86291c2b347b2995014591ea
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 DOCK10 ASCL1

1.21e-041303338bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

FOXE1 GPR87 NR1I2

1.23e-04131333ff4e618bd944f852bbd34438f740187aca82460f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 DOCK10 ASCL1

1.77e-041483335e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellControl-Epithelial-PNEC|World / Disease state, Lineage and Cell class

NPAS3 NOL4 ASCL1

1.81e-0414933302b47193621d23a50378d7905d7f85aaab686cfb
ToppCellControl-Epithelial-PNEC|Control / Disease state, Lineage and Cell class

NPAS3 NOL4 ASCL1

1.84e-04150333d6bbbe9d06a84c3de2a2e200ed512c8e8745f987
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 DOCK10 ASCL1

1.91e-041523338ff5a178a8f3550d89a003c0858820aab3773386
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

FOXE1 NPAS3 GPR87

1.95e-04153333a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 CD79B RP2

2.11e-04157333ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellCOPD-Epithelial-PNEC|COPD / Disease state, Lineage and Cell class

NPAS3 NOL4 ASCL1

2.19e-041593336018124980c55190928409f3bf41d846a118954a
ToppCellCOPD-Epithelial-PNEC|World / Disease state, Lineage and Cell class

NPAS3 NOL4 ASCL1

2.23e-04160333cdea93317b0ebb801ddbe73bca6149ce2c727f16
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

FOXE1 NPAS3 CD79B

2.31e-0416233391ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

FOXE1 NPAS3 GPR87

2.35e-04163333f21951e63188eb0c04675a8f81a0da495c26c007
ToppCellBAL-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

PHLDB1 ABL2 IL2RA

2.35e-041633337047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 CD79B RP2

2.44e-041653338a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 OTOF ASCL1

2.48e-041663339a341dc7b756252caeaac1e934384911c880a634
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 OTOF ASCL1

2.48e-04166333390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOXE1 DOCK10 DOCK9

2.52e-0416733383969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellfacs-MAT-Fat-18m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 OTOF VDR

2.52e-04167333c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK10 MYH11 IL2RA

2.52e-04167333ced6ed9b412739c6ced622523347c10295edbf53
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

DOCK10 CD79B IL2RA

2.57e-04168333a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPAS3 NOL4 ASCL1

2.61e-04169333b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NPAS3 NOL4 ASCL1

2.71e-04171333f4321133190a3df9d31f5d4021a464d3840145f1
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK10 CD79B IL2RA

2.71e-041713338e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NPAS3 NOL4 ASCL1

2.71e-04171333ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIF1A IL2RA SVOP

2.75e-041723333acf35b774ebc0f9e96299d0bd3e9d03bbf6b90c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIF1A IL2RA SVOP

2.75e-041723334d04df9776394ea156ed5822f92ae74fdefbaa3d
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NPAS3 NOL4 ASCL1

2.75e-04172333d0cdedd734406988a9a93d7300c7b1a8b4b45c38
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOL4 SVOP ASCL1

2.85e-041743339f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRMT13 MYH11 OTOF

2.85e-04174333c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABL2 IL2RA VDR

2.90e-04175333cddbd42c1cdfcdf2a41d96198ddb20e684ee6317
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABL2 IL2RA VDR

2.90e-04175333f5822cf48777880e670a6a18158ffb31d066c24a
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABL2 IL2RA VDR

2.90e-04175333067f77c5d9ae3cf960b84ece80c25d5193873cbf
ToppCellmild_COVID-19_(asymptomatic)-B_memory|World / disease group, cell group and cell class (v2)

CD79B UPF2 IL2RA

2.99e-04177333057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 CFAP47 ASCL1

2.99e-041773336f3b254e56e722cc23495b49e99a4abce0243cb3
ToppCellMild-Treg|Mild / Disease group and Cell class

CD79B IL2RA VDR

3.04e-04178333e669fd95278e145f55126d0e6be8fb2d6184dbbd
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 GPR87 IL2RA

3.09e-041793338bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

NPAS3 NOL4 ASCL1

3.09e-04179333988d0853c391da1e5004f73f3678047418d3f6d3
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NOL4 SVOP ASCL1

3.09e-04179333e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NOL4 SVOP ASCL1

3.09e-04179333af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EEF2K MYH11 RP2

3.15e-04180333eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EEF2K MYH11 RP2

3.15e-04180333ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEF2K PHLDB1 IL2RA

3.20e-04181333d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEF2K PHLDB1 IL2RA

3.20e-04181333e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

NPAS3 NOL4 ASCL1

3.25e-0418233357bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellwk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NOL4 SVOP ASCL1

3.35e-041843339e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPAS3 DOCK10 ASCL1

3.41e-0418533379cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

NPAS3 NOL4 ASCL1

3.41e-04185333f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPAS3 DOCK10 CD79B

3.41e-041853334c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CXorf58 CD79B IL2RA

3.41e-04185333a86a3a1a187a4d8d7762bc6d3dcb22c982178d22
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK10 SVOP ASCL1

3.41e-04185333512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

DOCK10 MYH11 IL2RA

3.46e-04186333acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

DOCK10 MYH11 IL2RA

3.46e-0418633367b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RP2 IL2RA VDR

3.46e-04186333bca5215d406f1785bf3a420201d5686071fcaca5
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPAS3 NOL4 ASCL1

3.46e-04186333b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

PHLDB1 MYH11 CIB4

3.52e-0418733362759efb660179402fb574ce5701c89a2e17bcfe
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

UPF2 OTOF SVOP

3.57e-04188333e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PHLDB1 MYH11 CIB4

3.57e-04188333ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 ASCL1

3.57e-041883333cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.63e-04189333979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 SVOP CIB4

3.63e-0418933363449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.68e-0419033356cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PHLDB1 MYH11 CIB4

3.68e-041903334eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PHLDB1 MYH11 CIB4

3.68e-041903337be4341e2909101d756f14031c21e705eb45e69a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.68e-0419033325d4b591f75c26e404a34c42f1742d580af6598d
ToppCellControl-B_intermediate-14|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DOCK10 CD79B IL2RA

3.74e-04191333076302fd247aab6c0b187ac9e0c67a3ba46414ba
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 ASCL1

3.74e-0419133319832ddd559a353e1618fe853d79e3edfec6dcda
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 ASCL1

3.80e-041923334d3a1c267739b1479217144656986972fc86db43
ToppCellNS-critical-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK10 CD79B IL2RA

3.80e-04192333cd34defac6565d34db507918e791b09c79f7d1f8
ToppCellHealthy/Control-B_intermediate|World / Disease group and Cell class

CD79B UPF2 IL2RA

3.80e-041923332266aa695955f5d885708e6bc0d5a8827c306223
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.80e-04192333342842378c20267c5044bdd622515e8b9f895623
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGSL1 NR1I2 OTOF

3.86e-04193333315840bc48899f3a36d57b19197509de19716e3d
ToppCellmetastatic_Lymph_Node-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

CD79B IL2RA VDR

3.86e-04193333bac302e69455aaaf1c18f3272bb213242664d747
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPAS3 NOL4 ASCL1

3.86e-041933338603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

HIF1A OTOF PARP12

3.92e-04194333d1366b169d14011194e61d16b6b0953349febc78
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

CD79B IL2RA VDR

3.92e-04194333e46963d5f156526342ebc0fb9e767d266e812c42
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.92e-041943335d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCell368C-Myeloid-Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PHLDB1 HIF1A ABL2

3.92e-04194333f9b9cbd1a418a7cbd151c2425fda6b864db9aa82
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.92e-041943336ac759828c41ffa974ee82842162caa959351dd1
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NOL4 OTOF SVOP

3.92e-041943332dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCelltumor_Lung-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

CD79B IL2RA VDR

3.97e-04195333dd112ef3f8bd0790719827b6bb120918687afdff
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK10 MYH11 ASCL1

3.97e-0419533398ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell11.5-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

NPAS3 NOL4 ASCL1

3.97e-04195333eda6ebe52c48bd6a9044886e75f584f46c2556e7
ToppCell368C-Myeloid-Monocyte-CD14+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PHLDB1 HIF1A ABL2

3.97e-041953338da933942e9033e18e25ab47831c269747b1c0b2
ToppCellmedial-2-Hematologic-IGSF21+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NPAS3 IL2RA VDR

3.97e-04195333bb612979360b2322289545dda3d3c343d005ee6f
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NPAS3 NOL4 CIB4

3.97e-04195333f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
Drug3-ketolithocholic acid

NR1I2 VDR

6.11e-063332ctd:C455860
Drug3-oxocholan-24-oic acid

NR1I2 VDR

6.11e-063332ctd:C046230
DrugThalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A

NPAS3 CD79B IL2RA DOCK9 PARP12

8.55e-061953355990_UP
DiseaseAPOE carrier status, cerebral amyloid angiopathy

DOCK10 YTHDC2

8.96e-0442312EFO_0006790, EFO_0007659
DiseaseMultiple Sclerosis

IL2RA VDR

1.03e-0345312C0026769
DiseaseMultiple Sclerosis, Acute Fulminating

IL2RA VDR

1.03e-0345312C0751324
Diseaseresponse to fenofibrate

NPAS3 IL2RA

1.27e-0350312GO_1901557
Diseaseinflammatory biomarker measurement, YKL40 measurement

MYH11 VDR

1.32e-0351312EFO_0004869, EFO_0004872
DiseaseBipolar Disorder

NPAS3 HIF1A DOCK9 VDR

1.50e-03477314C0005586
DiseaseMajor Depressive Disorder

NPAS3 HIF1A IL2RA

2.09e-03243313C1269683
DiseaseUnipolar Depression

NPAS3 HIF1A IL2RA

2.51e-03259313C0041696
Diseaseasthma, response to diisocyanate

NPAS3 NOL4 IL2RA

2.56e-03261313EFO_0006995, MONDO_0004979
Diseasemultiple sclerosis (is_implicated_in)

IL2RA VDR

2.68e-0373312DOID:2377 (is_implicated_in)
Diseasesusceptibility to strep throat measurement

IL2RA GPR139

2.90e-0376312EFO_0008408

Protein segments in the cluster

PeptideGeneStartEntry
CEGCKGFFRRSMKRK

VDR

41

P11473
GFFRRSMKRKALFTC

VDR

46

P11473
TMQCKIRFRFRGETF

CXorf58

96

Q96LI9
RDRKGGFFSSFMKKR

ABL2

646

P42684
RFIARKRGFTVKMHC

CD79B

51

P40259
SFFLRMKCTLTSRGR

HIF1A

166

Q16665
CKGFFRRAMKRNARL

NR1I2

61

O75469
FMCRSFSRRLFKKSN

GPR87

316

Q9BY21
RFMVYGACKFLRAGK

PARP12

96

Q9H0J9
KAMLFTLKRDRFSFL

OCR1

56

Q9BZK8
VARFLKRCFTFMDRG

DOCK10

1056

Q96BY6
LAVFIKRCFTFMDRG

DOCK9

1026

Q9BZ29
KRCFTFMDRGFVFKQ

DOCK9

1031

Q9BZ29
LMRCKRRLNFSGFGY

ASCL1

96

P50553
RYCEKSMISRKLFGF

DDX12P

516

Q92771
CKRGFRRIKSGSLYM

IL2RA

51

P01589
GAMRECFRTKKLSNF

EEF2K

141

O00418
RFRTMAAATLKAFFK

GPR139

291

Q6DWJ6
RSMFTFVCGQLFRRK

FBXO30

516

Q8TB52
RGFFMKTCFRGTVRL

CFAP47

861

Q6ZTR5
KSFRRAGRSVFSAMK

OTOF

166

Q9HC10
CSMLRGDFRFHVRKK

UPF2

641

Q9HAU5
ISFIRSFCKYRRFML

RGSL1

796

A5PLK6
SFCKYRRFMLNPSKR

RGSL1

801

A5PLK6
KKRFCRMVVAAGKRF

TRMT13

26

Q9NUP7
RLGRKKTMALCFVIF

SVOP

396

Q8N4V2
MFESGSFLRRRKRFK

FOXE1

136

O00358
RSFFIRMKSTLTKRG

NPAS3

261

Q8IXF0
TYLKSCRRMKRSGFE

NOL4

461

O94818
FRDRICRVFSHKGMF

CIB4

66

A0PJX0
MCRGYLARKAFAKRQ

MYH11

796

P35749
FQKRRFQFFCSMRCR

SPDYE3

506

A6NKU9
MGCFFSKRRKADKES

RP2

1

O75695
RSAAKKRFFRFTMVT

PHLDB1

1316

Q86UU1
RSFQIVCAFKMASRF

TAS1R2

651

Q8TE23
AAMLCRKRFTAGAFS

YTHDC2

881

Q9H6S0
MKKAGRCYFSSARIR

TTLL13

716

A6NNM8