Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

FUT3 FUT6

1.96e-046732GO:0017083
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF594 DEAF1 ZNF33A SATB1 ZNF556 TRPS1 ZNF521 ZNF814 MECOM ZNF736 ZNF510 HCFC1 ZNF529 ZNF840P ZNF587B

2.16e-0414597315GO:0000977
GeneOntologyMolecularFunctionalpha-(1->3)-fucosyltransferase activity

FUT3 FUT6

3.64e-048732GO:0046920
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF594 DEAF1 ZNF33A SATB1 ZNF556 TRPS1 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF840P ZNF587B

5.23e-0414127314GO:0000981
GeneOntologyBiologicalProcesssecretion

PCSK1 TGM2 SCN11A FBN1 NRXN1 PLA2G12B BTK GNPTAB PI4K2A OAS2 PRKCQ HMGCR CYB5R4 SCIN HCFC1

1.99e-0512217315GO:0046903
GeneOntologyCellularComponentpodosome

SCIN TNS3 AFAP1L1

3.96e-0441733GO:0002102
GeneOntologyCellularComponentextracellular matrix

TGFBI TGM2 LAMB4 FBN1 FN1 SPOCK3 MUC5B ANGPTL7 HCFC1

4.52e-04656739GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TGFBI TGM2 LAMB4 FBN1 FN1 SPOCK3 MUC5B ANGPTL7 HCFC1

4.62e-04658739GO:0030312
GeneOntologyCellularComponentaxonal growth cone

SCN11A NRXN1 LRP2

5.22e-0445733GO:0044295
GeneOntologyCellularComponentbasement membrane

TGFBI LAMB4 FBN1 FN1

8.81e-04122734GO:0005604
DomainEGF_1

LAMB4 FBN1 FN1 NRXN1 ADAM23 JAG1 LRP2 ADAM32

6.09e-06255728PS00022
DomainEGF-like_CS

LAMB4 FBN1 FN1 NRXN1 ADAM23 JAG1 LRP2 ADAM32

7.22e-06261728IPR013032
DomainZnf_C2H2-like

ZNF594 ZNF33A ZNF556 TRPS1 RBM6 RBM5 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

9.59e-067967213IPR015880
DomainZnF_C2H2

ZNF594 ZNF33A ZNF556 TRPS1 RBM6 RBM5 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

1.13e-058087213SM00355
DomainZINC_FINGER_C2H2_2

ZNF594 ZNF33A ZNF556 TRPS1 RBM5 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

3.72e-057757212PS50157
DomainZINC_FINGER_C2H2_1

ZNF594 ZNF33A ZNF556 TRPS1 RBM5 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

3.82e-057777212PS00028
DomainZnf_C2H2

ZNF594 ZNF33A ZNF556 TRPS1 RBM5 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

5.38e-058057212IPR007087
Domainzf-C2H2

ZNF594 ZNF33A ZNF556 TRPS1 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

6.52e-056937211PF00096
DomainEGF_2

LAMB4 FBN1 NRXN1 ADAM23 JAG1 LRP2 ADAM32

7.18e-05265727PS01186
DomainEGF_extracell

ADAM23 JAG1 LRP2 ADAM32

8.41e-0560724IPR013111
DomainEGF_2

ADAM23 JAG1 LRP2 ADAM32

8.41e-0560724PF07974
Domain-

ZNF594 ZNF33A ZNF556 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

2.65e-0467972103.30.160.60
DomainEGF_3

FBN1 NRXN1 ADAM23 JAG1 LRP2 ADAM32

2.91e-04235726PS50026
DomainEGF

FBN1 NRXN1 ADAM23 JAG1 LRP2 ADAM32

2.91e-04235726SM00181
DomainZnf_C2H2/integrase_DNA-bd

ZNF594 ZNF33A ZNF556 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

3.15e-046947210IPR013087
DomainEGF-like_dom

FBN1 NRXN1 ADAM23 JAG1 LRP2 ADAM32

3.96e-04249726IPR000742
DomainGlyco_transf_10

FUT3 FUT6

4.04e-048722PF00852
DomainGlyco_tran_10_N

FUT3 FUT6

4.04e-048722PF17039
DomainGlyco_trans_10

FUT3 FUT6

4.04e-048722IPR001503
DomainGlyco_tran_10_N

FUT3 FUT6

4.04e-048722IPR031481
DomainKRAB

ZNF33A ZNF556 ZNF814 ZNF736 ZNF510 ZNF529 ZNF587B

4.53e-04358727PS50805
DomainKRAB

ZNF33A ZNF556 ZNF814 ZNF736 ZNF510 ZNF529 ZNF587B

4.53e-04358727PF01352
DomainKRAB

ZNF33A ZNF556 ZNF814 ZNF736 ZNF510 ZNF529 ZNF587B

5.43e-04369727SM00349
DomainKRAB

ZNF33A ZNF556 ZNF814 ZNF736 ZNF510 ZNF529 ZNF587B

5.52e-04370727IPR001909
DomainASX_HYDROXYL

FBN1 NRXN1 JAG1 LRP2

6.02e-04100724PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 NRXN1 JAG1 LRP2

7.50e-04106724IPR000152
DomainGelsolin

SCIN SEC23B

1.29e-0314722PF00626
DomainFN_type2_col-bd

FN1 LY75

1.29e-0314722IPR000562
DomainFN2_2

FN1 LY75

1.29e-0314722PS51092
DomainGelsolin-like_dom

SCIN SEC23B

1.29e-0314722IPR007123
DomainTIL_dom

LRP2 MUC5B

1.29e-0314722IPR002919
Domainfn2

FN1 LY75

1.29e-0314722PF00040
DomainFN2_1

FN1 LY75

1.29e-0314722PS00023
DomainFN2

FN1 LY75

1.29e-0314722SM00059
DomainPI3/4_kinase_cat_dom

SMG1 PI4K2A

2.15e-0318722IPR000403
DomainPI3_PI4_kinase

SMG1 PI4K2A

2.15e-0318722PF00454
DomainPI3_4_KINASE_3

SMG1 PI4K2A

2.15e-0318722PS50290
DomainPI3_4_KINASE_1

SMG1 PI4K2A

2.15e-0318722PS00915
DomainPI3_4_KINASE_2

SMG1 PI4K2A

2.15e-0318722PS00916
DomainADAM_CR

ADAM23 ADAM32

2.15e-0318722PF08516
DomainVWC_out

JAG1 MUC5B

2.40e-0319722SM00215
Domain-

ADAM23 ADAM32

2.66e-03207224.10.70.10
DomainDisintegrin

ADAM23 ADAM32

2.94e-0321722PF00200
Domainzf-MYND

ZMYND19 DEAF1

2.94e-0321722PF01753
DomainDISIN

ADAM23 ADAM32

2.94e-0321722SM00050
DomainZnf_MYND

ZMYND19 DEAF1

3.22e-0322722IPR002893
DomainZF_MYND_1

ZMYND19 DEAF1

3.22e-0322722PS01360
DomainZF_MYND_2

ZMYND19 DEAF1

3.22e-0322722PS50865
DomainG_patch

RBM6 RBM5

3.52e-0323722SM00443
DomainG_patch_dom

RBM6 RBM5

3.52e-0323722IPR000467
DomainG_PATCH

RBM6 RBM5

3.52e-0323722PS50174
DomainG-patch

RBM6 RBM5

3.52e-0323722PF01585
DomainADF-H/Gelsolin-like_dom

SCIN SEC23B

3.83e-0324722IPR029006
Domain-

SCIN SEC23B

3.83e-03247223.40.20.10
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

VPS39 TRPS1 MECOM UPF1 HCFC1 NUP160

3.33e-0712874623858473
Pubmed

Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix.

TGM2 FN1

4.47e-06274222442151
Pubmed

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.

TGM2 FN1

4.47e-06274221368175
Pubmed

Fibrillin assembly requires fibronectin.

FBN1 FN1

4.47e-06274219037100
Pubmed

A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3.

RBM6 RBM5

4.47e-06274210352938
Pubmed

Involvement of tissue transglutaminase in the stabilisation of biomaterial/tissue interfaces important in medical devices.

TGM2 FN1

4.47e-06274211829448
Pubmed

Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain.

TGM2 FN1

4.47e-06274227685605
Pubmed

Correlation of FUT3 and FUT6 Gene Polymorphisms With Helicobacter pylori Infection.

FUT3 FUT6

4.47e-06274239108208
Pubmed

Up-regulation of fibronectin and tissue transglutaminase promotes cell invasion involving increased association with integrin and MMP expression in A431 cells.

TGM2 FN1

4.47e-06274221036738
Pubmed

Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbeta-dependent matrix deposition.

TGM2 FN1

4.47e-06274211686302
Pubmed

FN1 and TGFBI are key biomarkers of macrophage immune injury in diabetic kidney disease.

TGFBI FN1

4.47e-06274237960829
Pubmed

Selective integrin subunit reduction disrupts fibronectin extracellular matrix deposition and fibrillin 1 gene expression.

FBN1 FN1

4.47e-06274222782528
Pubmed

An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers.

RBM6 RBM5

4.47e-06274210486216
Pubmed

RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours.

RBM6 RBM5

4.47e-06274217908320
Pubmed

Fibrillin-1 microfibril deposition is dependent on fibronectin assembly.

FBN1 FN1

4.47e-06274218653538
Pubmed

Dissecting the interaction between transglutaminase 2 and fibronectin.

TGM2 FN1

4.47e-06274227394141
Pubmed

Complex contributions of fibronectin to initiation and maturation of microfibrils.

FBN1 FN1

4.47e-06274224070235
Pubmed

Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein.

SMG1 UPF1

4.47e-06274211331269
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 VPS39 USP9X CCSER2 RBM6 UPF1 CAMSAP1 NUP160

4.47e-0644074834244565
Pubmed

Human transcription factor protein interaction networks.

SMG1 FBN1 DEAF1 SATB1 USP9X TRPS1 RBM6 LRP2 ZNF521 MECOM UPF1 HCFC1 SEC23B

9.12e-061429741335140242
Pubmed

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation.

PI4K2A ZFYVE26

1.34e-05374233618608
Pubmed

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow.

TGM2 FN1

1.34e-05374228387755
Pubmed

Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.

FUT3 FUT6

1.34e-0537427650030
Pubmed

Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.

FUT3 FUT6

1.34e-05374230808544
Pubmed

The interaction of angiocidin with tissue transglutaminase.

TGM2 FN1

1.34e-05374219931242
Pubmed

Transglutaminase-Mediated Cross-Linking of Tropoelastin to Fibrillin Stabilises the Elastin Precursor Prior to Elastic Fibre Assembly.

TGM2 FBN1

1.34e-05374232898582
Pubmed

MUC5B mucin production is upregulated by fibronectin and laminin in human lung epithelial cells via the integrin and ERK dependent pathway.

FN1 MUC5B

1.34e-05374226057585
Pubmed

Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab.

FUT3 FUT6

1.34e-05374220179215
Pubmed

Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells.

SMG1 UPF1

1.34e-05374224173962
Pubmed

Metastasis suppressor KAI1/CD82 attenuates the matrix adhesion of human prostate cancer cells by suppressing fibronectin expression and β1 integrin activation.

CD82 FN1

1.34e-05374221691075
Pubmed

A role for PKCtheta in outside-in alpha(IIb)beta3 signaling.

BTK PRKCQ

1.34e-05374216460447
Pubmed

Molecular structure and interaction of recombinant human type XVI collagen.

FBN1 FN1

1.34e-05374215165854
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN1 THSD7A NRXN1 LRP2

1.65e-057174433541421
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 FN1 JAG1

2.32e-052674334189436
Pubmed

The transforming growth factor-beta-inducible matrix protein (beta)ig-h3 interacts with fibronectin.

TGFBI FN1

2.67e-05474212034705
Pubmed

Immunolocalization of microfibril and microfibril-associated proteins in the subendothelial matrix of the developing mouse aorta.

FBN1 FN1

2.67e-0547428006086
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FN1

2.67e-05474225034023
Pubmed

RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation.

RBM6 RBM5

2.67e-05474224332178
Pubmed

Activation of ephrin A proteins influences hematopoietic stem cell adhesion and trafficking patterns.

EFNA3 FN1

2.67e-05474220655977
Pubmed

Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.

FUT3 FUT6

2.67e-05474219349624
Pubmed

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.

SMG1 UPF1

2.67e-05474211544179
Pubmed

Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase-fibronectin complex.

TGM2 FN1

2.67e-05474221036168
Pubmed

ZFP521 contributes to pre-B-cell lymphomagenesis through modulation of the pre-B-cell receptor signaling pathway.

BTK ZNF521

2.67e-05474226522721
Pubmed

EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation.

TGM2 FN1

2.67e-05474220080707
Pubmed

Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell death.

TGM2 FN1

2.67e-0547429511731
Pubmed

Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma.

TGM2 FN1

2.67e-05474223765377
Pubmed

Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19.

FUT3 FUT6

2.67e-0547427656588
Pubmed

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.

SMG1 UPF1

2.67e-05474215175154
Pubmed

Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling.

TGM2 FN1

2.67e-05474218499669
Pubmed

B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection.

BTK LY75

2.67e-05474236882061
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

TGFBI TGM2 FBN1 FN1 HCFC1

2.96e-0516774522159717
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

TGFBI TGM2 FBN1 FN1

3.51e-058674428327460
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

TGFBI TGM2 FBN1 FN1 HCFC1

3.71e-0517574528071719
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF33A YPEL5 ZNF736 ZNF529 ZNF587B

4.35e-0518174537372979
Pubmed

Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

FUT3 FUT6

4.45e-05574229593094
Pubmed

Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.

TGM2 FN1

4.45e-05574211278623
Pubmed

The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.

SMG1 UPF1

4.45e-05574226841701
Pubmed

Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay.

SMG1 UPF1

6.66e-05674225770585
Pubmed

Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases.

BTK PRKCQ

6.66e-05674211788586
Pubmed

Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

SMG1 UPF1

6.66e-05674212554878
Pubmed

Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

TGM2 FBN1

6.66e-05674219182256
Pubmed

Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners.

TGM2 FN1

6.66e-05674230082873
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FN1 USP9X ZC3H13 RBM6 UPF1 HCFC1 NUP160 SEC23B

7.50e-0565374822586326
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FBN1 FN1 SATB1 ADAM23 VPS39 USP9X GNPTAB TRPS1 LRP2 ZNF521 TTC27

8.30e-051285741135914814
Pubmed

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.

FBN1 JAG1

9.31e-05774229093270
Pubmed

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

SMG1 UPF1

9.31e-05774214636577
Pubmed

Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells.

FBN1 FN1

9.31e-05774221778429
Pubmed

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.

FUT3 FUT6

9.31e-05774221203500
Pubmed

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.

SMG1 UPF1

9.31e-05774217916692
Pubmed

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.

SMG1 UPF1

9.31e-05774218256688
Pubmed

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

PCSK1 PLA2G12B ZFYVE26

1.15e-044474327534441
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 THSD7A NRXN1 VPS39 GNPTAB

1.21e-0422574512168954
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

FBN1 FN1

1.24e-04874223055981
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

TGFBI FN1

1.24e-04874211867580
Pubmed

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.

JAG1 MCF2

1.24e-04874224647000
Pubmed

Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis.

FBN1 BTK

1.24e-04874222542159
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

LRP2 MUC5B HMGCR

1.40e-044774311208732
Pubmed

Integral and associated lysosomal membrane proteins.

VPS39 PI4K2A LRP2 ZFYVE26

1.55e-0412674417897319
Pubmed

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability.

SMG1 UPF1

1.59e-04974216488880
Pubmed

Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells.

FNTB HMGCR

1.59e-04974233207246
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 JAG1

1.59e-04974212122015
Pubmed

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.

NRXN1 JAG1

1.59e-0497429707552
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 FN1

1.59e-04974238844137
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TGM2 RBM5 MECOM HMGCR CAMSAP1 HCFC1 TNS3 AFAP1L1

1.66e-0473374834672954
Pubmed

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.

FBN1 FN1

1.99e-041074230738849
Pubmed

Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

VPS39 PI4K2A

1.99e-041074219010779
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

FBN1 FN1

1.99e-04107429415455
Pubmed

Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases.

BTK PRKCQ

1.99e-041074215814670
Pubmed

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome.

JAG1 LRP2

1.99e-041074230046000
Pubmed

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay.

SMG1 UPF1

1.99e-041074218423202
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

TGFBI TGM2 FBN1 FN1

2.02e-0413574428675934
Pubmed

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias.

ZNF521 MECOM

2.43e-04117428563752
Pubmed

Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex.

FN1 SATB1

2.43e-041174221940705
Pubmed

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

JAG1 LRP2

2.43e-041174222999937
Pubmed

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.

USP9X UPF1 HCFC1

2.49e-045774338223760
Pubmed

Functional proteomics mapping of a human signaling pathway.

SMG1 TGM2 THSD7A FN1 ZNF510 CAMSAP1 ZNF587B

2.66e-0459174715231748
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

SATB1 TRPS1 LRP2 TTC27 MECOM CAMSAP1

2.70e-0441874634709266
Pubmed

The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.

SMG1 UPF1

2.91e-041274231732746
Pubmed

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.

FBN1 FN1

2.91e-041274226405179
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

TGFBI TGM2 FBN1 FN1

3.26e-0415374425037231
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF594 ZNF33A ZNF556 TRPS1 ZNF521 ZNF814 MECOM ZNF736 ZNF510 ZNF529 ZNF587B

8.70e-06718551128
GeneFamilyFucosyltransferases|Blood group antigens

FUT3 FUT6

6.94e-0413552434
GeneFamilyZinc fingers MYND-type

ZMYND19 DEAF1

1.84e-032155287
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

RBM6 RBM5

2.02e-0322552579
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM23 ADAM32

3.04e-032755247
CoexpressionFOROUTAN_INTEGRATED_TGFB_EMT_UP

TGFBI TGM2 FBN1 FN1 JAG1 TP53I3

1.08e-06120736M42505
CoexpressionSCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP

TGFBI TGM2 FBN1 THSD7A FN1 TP53I3 ADGRF5 TNS3

6.15e-06352738M17471
CoexpressionFOROUTAN_PRODRANK_TGFB_EMT_UP

TGFBI TGM2 FBN1 FN1 JAG1 TP53I3

1.31e-05185736M42503
CoexpressionFOROUTAN_TGFB_EMT_UP

TGFBI TGM2 FBN1 FN1 JAG1 TP53I3

1.62e-05192736M42501
CoexpressionGSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP

ADAM23 JAG1 BTK CHEK2 CAMSAP1 NUP160

1.98e-05199736M9410
CoexpressionDESCARTES_FETAL_THYMUS_VASCULAR_ENDOTHELIAL_CELLS

TGM2 THSD7A ZNF521 MECOM ADGRF5

3.30e-05131735M40316
CoexpressionMEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_INDEPENDENT

TGFBI FBN1 FN1

4.02e-0524733M38986
CoexpressionTRAVAGLINI_LUNG_GOBLET_CELL

TGM2 CD82 MUC5B FUT3 FUT6

5.91e-05148735M41655
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

TGM2 CD82 FN1 JAG1 MECOM OAS2 ADGRF5

7.10e-05365737M39018
CoexpressionODONNELL_TARGETS_OF_MYC_AND_TFRC_UP

ZNF594 SATB1 YPEL5 FUT6

8.61e-0583734M13183
CoexpressionPETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN

TGFBI TGM2 TP53I3 MECOM LY75

9.07e-05162735M1459
CoexpressionHU_FETAL_RETINA_FIBROBLAST

TGFBI TGM2 FBN1 FN1 JAG1 TP53I3 SCIN

9.90e-05385737M39264
CoexpressionNABA_MATRISOME

TGFBI TGM2 LAMB4 FBN1 FN1 ADAM23 SPOCK3 MUC5B ADAM32 ANGPTL7 HCFC1

1.21e-0410267311M5889
CoexpressionNAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_DN

TGFBI FNTB RBM5 ZFYVE26 UPF1 CAMSAP1 SEC23B

1.23e-04399737M40939
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBN1 THSD7A JAG1 MECOM ADGRF5 SCIN

4.98e-071797361ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SCN11A THSD7A FN1 JAG1 MECOM ADGRF5

8.21e-0719573675db19c0371320ea5fce1d6de8c1b40b1e6a2e58
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGM2 TP53I3 MECOM MUC5B FUT3 FUT6

8.71e-07197736a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 THSD7A FN1 JAG1 MECOM ADGRF5

9.51e-072007365ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI FN1 JAG1 TRPS1 LRP2

5.31e-061537350ef7c45cdd854c79e527006034029767f8e108b2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK1 FN1 SPOCK3 GNPTAB MCF2

7.44e-0616473543630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK1 FN1 SPOCK3 GNPTAB MCF2

7.44e-06164735108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK1 FN1 SPOCK3 GNPTAB MCF2

7.44e-0616473546208f18325976c89f572f6627aea0582142b92d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 FBN1 FN1 OAS2 ADGRF5

7.89e-061667359d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGM2 CD82 FBN1 FN1 TNS3

9.92e-061747353c47d069bd836599a8d40eae485c23d4d3487517
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

FBN1 FN1 ZC3H13 LY75 TNS3

1.11e-05178735edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 MECOM ADGRF5 TNS3 AFAP1L1

1.20e-05181735a53f05c4c47465ee62e353716456bd09ab464b23
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 MECOM ADGRF5 TNS3 AFAP1L1

1.27e-05183735709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 MECOM ADGRF5 TNS3 AFAP1L1

1.27e-05183735dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 THSD7A TXNRD3 MECOM SCIN

1.27e-05183735351d575339038bd4a66f408da518c567444208e8
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TGM2 CD82 FBN1 TRPS1 MECOM

1.33e-051857357dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 THSD7A FN1 JAG1 ADGRF5

1.33e-05185735f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

THSD7A ADAM23 ZNF521 MECOM AFAP1L1

1.33e-05185735f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TGM2 CD82 FBN1 TRPS1 MECOM

1.33e-051857359f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.33e-05185735602536a3308a848f106adcb0a83530997440c8f4
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CD82 FBN1 FN1 TRPS1 MECOM

1.33e-051857351ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGM2 MECOM OAS2 ADGRF5 AFAP1L1

1.37e-05186735422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGM2 MECOM OAS2 ADGRF5 AFAP1L1

1.37e-0518673565da0666a10a59f8cc379589860a2e98fe487754
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGM2 MECOM OAS2 ADGRF5 AFAP1L1

1.37e-05186735dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TGM2 CD82 FBN1 TRPS1 MECOM

1.40e-051877355258674d0346e5c51a4b965efcdc1790c970845d
ToppCellfacs-SCAT-Fat-24m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM2 CHEK2 MECOM ADGRF5 AFAP1L1

1.40e-0518773543e35ec995afd8780893de42ac4ee466794991d7
ToppCellfacs-SCAT-Fat-24m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM2 CHEK2 MECOM ADGRF5 AFAP1L1

1.40e-051877358ca9481d661626f6f0e1b61eb142b051192a9208
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TGM2 CD82 FBN1 TRPS1 MECOM

1.40e-0518773513731298bc562ec29582f5da1b4c97261284f6f1
ToppCellfacs-SCAT-Fat-24m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM2 CHEK2 MECOM ADGRF5 AFAP1L1

1.40e-0518773551336037dfd4bbe9fe9ce1e5b6b92d037156690c
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN11A THSD7A MECOM ADGRF5 AFAP1L1

1.40e-0518773525efb82afe863a853ecdd781ad89026c993aaa67
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TGM2 JAG1 MECOM ADGRF5 AFAP1L1

1.44e-05188735366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

FBN1 THSD7A FN1 JAG1 MECOM

1.44e-051887352777eb7689b271c199021fe7d9db88ccebff14de
ToppCellASK440-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

CD82 BTK GNPTAB TTC27 SCIN

1.48e-0518973572a19b20cb0f7283afe5f85d62a21cff69fd78d0
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

TGM2 THSD7A ZNF521 MECOM AFAP1L1

1.48e-051897357346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

FBN1 THSD7A SPOCK3 ZNF521 MECOM

1.48e-05189735555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 THSD7A FN1 JAG1 MECOM

1.48e-05189735c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGM2 FBN1 THSD7A JAG1 MECOM

1.48e-05189735360f09f46231a83f99d8fa0158b72a38068e1642
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 THSD7A FN1 JAG1 MECOM

1.52e-05190735aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGM2 THSD7A JAG1 MECOM ADGRF5

1.56e-0519173527f23c2254b610abac1a88d0fecff305addde9da
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 THSD7A FN1 JAG1 MECOM

1.56e-051917354b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

TGM2 THSD7A ZNF521 MECOM AFAP1L1

1.59e-05192735c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPOCK3 ZNF521 OAS2 ADGRF5 AFAP1L1

1.59e-05192735c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell15-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

TGM2 FBN1 FN1 ZNF521 AFAP1L1

1.63e-051937356ea0444fc3dc156997129387184e6418947f4b12
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.63e-051937356e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 THSD7A FN1 JAG1 ADGRF5

1.63e-051937352e72309607902dabe3218888b22a77fe941f3570
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.63e-05193735af5108260783e69a7d67896c5bf64f862525926d
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD7A NRXN1 ADAM23 ADGRF5 TNS3

1.63e-051937352483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell15-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

TGM2 FBN1 FN1 ZNF521 AFAP1L1

1.63e-05193735b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A FN1 JAG1 ADGRF5 SCIN

1.63e-05193735cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPOCK3 ZNF521 OAS2 ADGRF5 AFAP1L1

1.63e-05193735a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 FBN1 FN1 JAG1 ADGRF5

1.63e-051937350b328f725f6feba263783eaca60c142e80df90f3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 FN1 ZNF521 ADGRF5 AFAP1L1

1.63e-05193735287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 ZNF521 OAS2 ADGRF5 AFAP1L1

1.68e-05194735e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 JAG1 ADGRF5 AFAP1L1

1.72e-0519573577e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 ZNF521 OAS2 ADGRF5 AFAP1L1

1.76e-05196735023312af38f816a44b407e0daa32590d953caf99
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 FN1 ZNF521 ADGRF5 AFAP1L1

1.76e-0519673522767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI TGM2 FBN1 FN1 ADAM23

1.76e-05196735f47e551ba484687ba6ce8c29a085106131364042
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 FN1 ZNF521 ADGRF5 AFAP1L1

1.76e-05196735adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.76e-05196735629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 THSD7A FN1 JAG1 ADGRF5

1.80e-0519773561b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCellwk_20-22-Mesenchymal-Fibroblast-Airway_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TGM2 CD82 FBN1 FN1 MECOM

1.80e-05197735233caeee200ca905900226f85426e084caf290fb
ToppCell3'-Child09-12-SmallIntestine-Endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.80e-0519773586a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 THSD7A FN1 JAG1 MECOM

1.85e-051987358a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 THSD7A FN1 JAG1 MECOM

1.85e-05198735d1f54ed3ef5e05ebda7da999e172d168dc6802cd
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD82 SPOCK3 PLEKHG7 MUC5B FUT6

1.85e-05198735af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCell5'-Adult-Distal_Rectal-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGM2 THSD7A FN1 JAG1 MECOM

1.85e-051987358d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.85e-0519873513203249e5743ba2699871c184d141207e550a86
ToppCellSkin-Endothelial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

TGM2 FBN1 THSD7A ZNF521 AFAP1L1

1.89e-051997356b3ef5d8f87cdfe5401d05f19339ddfcd9cda476
ToppCell(02)_MMP9/10+-(1)_GFP|(02)_MMP9/10+ / shred by cell type by condition

TGFBI TGM2 FN1 JAG1 MUC5B

1.89e-05199735448ba982be804007f991d469eca9d885b21ae499
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 FN1 ZNF521 ADGRF5 AFAP1L1

1.89e-05199735da5a88749d859d535daa030d0974485906cc0ba7
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

TGM2 FBN1 FN1 CHEK2 TEX15

1.89e-05199735c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.89e-0519973597052c28e354833901f28d339b09f97f50a5b752
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.89e-05199735f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGM2 THSD7A FN1 JAG1 MECOM

1.89e-051997356a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNTB SPOCK3 BTK TXNRD3 SCIN

1.89e-051997356e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCellBronchial-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNTB SPOCK3 BTK TXNRD3 SCIN

1.89e-051997355f499595597c10857bba8272f62afe4d32d733ac
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

TGM2 FBN1 FN1 CHEK2 TEX15

1.94e-0520073564ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FBN1 FN1 JAG1 SCIN TNS3

1.94e-05200735ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FBN1 THSD7A FN1 JAG1 MECOM

1.94e-0520073577ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

FBN1 THSD7A FN1 JAG1 MECOM

1.94e-0520073565b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FBN1 THSD7A FN1 JAG1 MECOM

1.94e-05200735ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

THSD7A ZNF521 MECOM ADGRF5 AFAP1L1

1.94e-05200735ec92fe4eafe527d351ee73c9735e96855ac506a3
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

TGM2 FBN1 FN1 CHEK2 TEX15

1.94e-05200735a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

FBN1 THSD7A FN1 JAG1 MECOM

1.94e-05200735b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FBN1 THSD7A FN1 JAG1 MECOM

1.94e-05200735b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Cytl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CD82 FN1 JAG1 MECOM

2.59e-051047345d9cd14e53a2f1060e528abf6c0694be9d72c356
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Cytl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TGM2 FN1 MECOM ADGRF5

5.67e-05127734eee8e4a83f7de46807440d202d46eee7dd722001
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SCN11A FBN1 SATB1 ZNF510

9.48e-0514573442dd36c1bc2c43cfea7196e89f901e4ea2a403c7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A ADAM23 ADGRF5 SCIN

9.73e-05146734e887e9de895fd453faa703997ef372cc6410fc49
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

KIAA1328 PRKCQ ZNF510 LY75

1.03e-0414873480470353e12599440f711b6e107730763376d04d
ToppCellAdult-Immune-enucleated_erythrocyte-D175|Adult / Lineage, Cell type, age group and donor

NRXN1 PLA2G12B SPOCK3 MCF2

1.14e-04152734530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

JAG1 LRP2 FUT6 AFAP1L1

1.23e-0415573483430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK1 LAMB4 NRXN1 RNF17

1.35e-0415973422427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCN11A FN1 ADGRF5 TNS3

1.35e-041597347a5c94c87b73f928d4daee507f32cbe7d90e4478
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SMG1 TGM2 ZNF594 FN1

1.39e-041607340293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SMG1 TGM2 ZNF594 FN1

1.39e-041607343eaae86fa08f7651021316f8e5811bf48055591e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A MECOM ADGRF5 SCIN

1.42e-04161734176a4a72bb4892932da3c834d1fea5e211847f92
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI TGM2 ADAM23 TNS3

1.42e-0416173445591addc765760db6029ac19e80573373d1d917
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SPOCK3 MECOM ADAM32 FUT6

1.42e-04161734aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI TGM2 ADAM23 TNS3

1.42e-041617348741b91a62c9a8ce377ef6533d323b65beb93c63
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

THSD7A FN1 JAG1 MECOM

6.93e-0550484GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_NOTCH_SIGNALING
Drug17-AAG; Down 200; 1uM; MCF7; HG-U133A

CD82 ADAM23 VPS39 ZC3H13 CCSER2 PI4K2A PRKCQ SCIN

2.01e-07194738428_DN
DrugTrapidil [15421-84-8]; Up 200; 19.4uM; HL60; HT_HG-U133A

EFNA3 THSD7A FN1 TRPS1 PI4K2A TTC27 FUT3 FUT6

2.35e-071987383136_UP
DrugChlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A

SCN11A ADAM23 RBM5 OAS2 FUT3 CAMSAP1 RNF17

3.07e-061957373869_UP
DrugMonobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A

CD82 DEAF1 VPS39 JAG1 PI4K2A ZNF510 HCFC1

3.28e-061977375312_UP
DrugAustricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A

SCN11A CD82 LRP2 OAS2 TEX15 FUT6 HCFC1

3.28e-061977372812_UP
Drugiloprost; Down 200; 1uM; MCF7; HG-U133A

TGFBI TGM2 CD82 ADAM23 CCSER2 PI4K2A NUP160

3.28e-06197737427_DN
DrugNadolol [42200-33-9]; Down 200; 13uM; MCF7; HT_HG-U133A

CD82 FN1 ADAM23 GNPTAB DNAI2 OAS2 CAMSAP1

3.39e-061987374139_DN
DrugGriseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

TGM2 JAG1 ADGRF5 MUC5B PRKCQ TEX15 HCFC1

3.39e-061987372293_UP
DrugSparteine (-) [90-39-1]; Up 200; 17uM; HL60; HT_HG-U133A

EFNA3 PI4K2A LRP2 MECOM OAS2 ZNF510 CAMSAP1

3.63e-062007372134_UP
DrugHalofantrine hydrochloride [36167-63-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A

LAMB4 EFNA3 FBN1 DEAF1 DNAI2 PI4K2A CAMSAP1

3.63e-062007376509_UP
DrugFenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; PC3; HT_HG-U133A

TGFBI EFNA3 LRP2 OAS2 MUC5B FUT6

2.62e-051827366331_UP
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

TRPS1 CCSER2 PI4K2A RBM5 ZFYVE26 ZNF510

3.44e-051917364168_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

TGFBI VPS39 YPEL5 ZFYVE26 ZNF510 TNS3

3.54e-051927361059_UP
DrugFluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A

FN1 ZC3H13 PI4K2A OAS2 CAMSAP1 HCFC1

3.65e-051937364129_DN
DrugFlurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

FBN1 FN1 SPOCK3 GNPTAB LRP2 FUT6

3.86e-051957366039_UP
DrugRapamycin; Down 200; 0.1uM; PC3; HT_HG-U133A

EFNA3 RBM5 UPF1 FUT6 CAMSAP1 NUP160

3.86e-051957361207_DN
DrugCapsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A

JAG1 MECOM PRKCQ TEX15 FUT6 CAMSAP1

3.86e-051957365673_UP
DrugTobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

LAMB4 ADAM23 SPOCK3 MUC5B RNF17 HCFC1

3.86e-051957364162_UP
DrugPiracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A

EFNA3 DEAF1 ADAM23 OAS2 FUT6 HCFC1

3.86e-051957362861_UP
DrugSolanine alpha [20562-02-1]; Up 200; 4.6uM; HL60; HT_HG-U133A

LAMB4 SCN11A MECOM TEX15 FUT6 RNF17

3.86e-051957362152_UP
Drug2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A

SATB1 TRPS1 CCSER2 LRP2 MECOM FUT6

3.97e-051967361155_UP
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A

LAMB4 EFNA3 THSD7A PI4K2A FUT6 CAMSAP1

3.97e-051967363571_UP
DrugBenfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A

CD82 GNPTAB PI4K2A LRP2 ADGRF5 CAMSAP1

3.97e-051967363837_UP
DrugSulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A

FBN1 ZC3H13 GNPTAB PI4K2A CAMSAP1 HCFC1

3.97e-051967364724_UP
DrugDeferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A

TGM2 CD82 EFNA3 FN1 PI4K2A ANGPTL7

3.97e-051967364317_UP
DrugNitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

LAMB4 FN1 ADAM23 DNAI2 LRP2 FUT6

4.09e-051977366043_UP
DrugEstropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

TGM2 LAMB4 SCN11A MUC5B FUT6 CAMSAP1

4.09e-051977366068_UP
DrugCarisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

CD82 ADAM23 DNAI2 RBM5 FUT6 CAMSAP1

4.09e-051977364955_UP
DrugBenzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A

TGM2 CD82 FBN1 FN1 MUC5B FUT6

4.09e-051977364501_DN
DrugPilocarpine nitrate [148-72-1]; Up 200; 14.8uM; HL60; HT_HG-U133A

DEAF1 THSD7A ADAM23 DNAI2 CCSER2 NUP160

4.09e-051977362438_UP
DrugNifuroxazide [965-52-6]; Up 200; 14.6uM; HL60; HT_HG-U133A

SCN11A SPOCK3 ZC3H13 DNAI2 PI4K2A RNF17

4.09e-051977362490_UP
Drug2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A

DEAF1 CCSER2 PI4K2A RBM5 FUT6 NUP160

4.09e-051977361240_DN
DrugPF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A

LAMB4 FBN1 SPOCK3 CCSER2 PI4K2A HCFC1

4.09e-051977365939_DN
DrugTobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

TGM2 SPOCK3 GNPTAB PI4K2A OAS2 FUT6

4.21e-051987362841_UP
DrugNefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; PC3; HT_HG-U133A

FN1 RBM5 TEX15 FUT6 SCIN HCFC1

4.21e-051987363730_DN
DrugAlprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A

SCN11A SATB1 ADAM23 SPOCK3 OAS2 RNF17

4.21e-051987364179_UP
DrugBenzbromarone [3562-84-3]; Down 200; 9.4uM; HL60; HT_HG-U133A

CD82 DEAF1 VPS39 JAG1 PI4K2A HCFC1

4.21e-051987361291_DN
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

TGM2 EFNA3 LRP2 FUT6 CAMSAP1 HCFC1

4.21e-051987366812_UP
DrugLevopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; HL60; HT_HG-U133A

DEAF1 FN1 CCSER2 TTC27 ZNF510 UPF1

4.21e-051987362980_UP
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HG-U133A

CD82 ADAM23 CCSER2 FUT6 SCIN NUP160

4.21e-05198736426_DN
DrugBethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A

ADAM23 SPOCK3 DNAI2 RBM5 ADGRF5 TEX15

4.21e-051987363537_UP
DrugMethantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A

CD82 FN1 ADAM23 VPS39 PI4K2A ZNF510

4.21e-051987366254_UP
DrugReserpinic acid hydrochloride; Up 200; 9.2uM; HL60; HT_HG-U133A

EFNA3 FN1 PI4K2A TP53I3 OAS2 NUP160

4.33e-051997362903_UP
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A

PCSK1 LAMB4 NRXN1 BTK PRKCQ RNF17

4.33e-051997364284_UP
DrugBeta-sistosterol [83-46-5]; Up 200; 9.6uM; HL60; HT_HG-U133A

EFNA3 FN1 TP53I3 PRKCQ FUT6 RNF17

4.45e-052007362912_UP
DrugTropine [120-29-6]; Up 200; 28.4uM; MCF7; HT_HG-U133A

SCN11A EFNA3 FN1 RBM5 OAS2 FUT6

4.45e-052007366264_UP
DrugFamprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A

FN1 DNAI2 LRP2 MUC5B PRKCQ FUT3

4.45e-052007366029_UP
DrugPivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; PC3; HT_HG-U133A

FN1 CCSER2 OAS2 TEX15 FUT3 FUT6

4.45e-052007367312_UP
DrugMagnetite Nanoparticles

ZMYND19 TGFBI SMG1 TGM2 FN1 USP9X ZC3H13 JAG1 TRPS1 RBM5 MECOM OAS2 CYB5R4 SCIN

6.15e-0513107314ctd:D058185
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

TGM2 LAMB4 FBN1 FN1

1.48e-0483734CID011968896
DrugAC1MPID6

FUT3 FUT6

1.51e-046732CID003411618
DrugSuccimer

ZMYND19 SMG1 TGM2 FN1 USP9X ZC3H13 JAG1 TRPS1 RBM5 MECOM OAS2 CYB5R4 SCIN

1.71e-0412647313ctd:D004113
DrugPerhexiline maleate [6724-53-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A

CD82 OAS2 HMGCR FUT3 HCFC1

2.18e-041707355501_UP
Drug4'-Aagb

JAG1 FUT3 HCFC1

2.27e-0437733CID000001718
Drugfluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA

SCN11A PI4K2A HMGCR FUT6 CAMSAP1

2.30e-041727351017_UP
DrugSureCN4141578

FN1 RBM5

2.80e-048732CID011594966
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

TGFBI YPEL5 PI4K2A ZFYVE26 ZNF510

2.91e-041817351077_UP
Druggeldanamycin; Up 200; 1uM; MCF7; HG-U133A

VPS39 RBM5 HMGCR FUT6 SEC23B

2.99e-04182735593_UP
DrugMetergoline [17692-51-2]; Up 200; 10uM; MCF7; HT_HG-U133A

SCN11A PI4K2A PRKCQ HMGCR FUT6

3.07e-041837353221_UP
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CD82 GNPTAB TRPS1 MECOM FUT6

3.07e-041837355613_DN
DrugChloroprene

PCSK1 FBN1 FN1 SATB1 NRXN1 ZC3H13 TRPS1 DNAI2 CCSER2 LRP2 RBM5 ZNF521 ANGPTL7

3.21e-0413487313ctd:D002737
DrugChlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A

EFNA3 FN1 PI4K2A ZNF510 HCFC1

3.47e-041887355493_UP
DrugQ U I

TGFBI CD82 FUT3

3.56e-0443733CID000078857
DrugKCC 009

TGM2 FN1

3.60e-049732ctd:C510621
DrugAC1NRAX5

FN1 UPF1

3.60e-049732CID005288137
Drug0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A

TGM2 ADAM23 ZC3H13 PI4K2A NUP160

3.64e-041907353733_UP
DrugHarmine hydrochloride [343-27-1]; Up 200; 16uM; MCF7; HT_HG-U133A

LAMB4 MCF2 ZNF510 TEX15 FUT6

3.64e-041907357209_UP
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

CD82 JAG1 OAS2 TEX15 FUT3

3.64e-041907356979_UP
DrugTubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A

TGM2 SCN11A CD82 RBM5 MECOM

3.64e-041907352887_UP
Drug2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A

EFNA3 FN1 SPOCK3 JAG1 MECOM

3.73e-041917351665_UP
DrugThioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A

TGM2 OAS2 MUC5B TEX15 FUT3

3.73e-041917353392_UP
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

CD82 FBN1 FN1 OAS2 ZNF510

3.73e-041917352368_UP
DrugGramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A

SCN11A CD82 OAS2 FUT6 CAMSAP1

3.82e-041927352799_UP
DrugAntimycin A [1397-94-0]; Up 200; 7.2uM; MCF7; HT_HG-U133A

TGFBI ADAM23 PI4K2A TEX15 FUT6

3.82e-041927352261_UP
DrugOrlistat; Up 200; 10uM; PC3; HT_HG-U133A

LAMB4 JAG1 OAS2 FUT6 CAMSAP1

3.82e-041927356388_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HG-U133A

TGM2 CD82 EFNA3 ZC3H13 SEC23B

3.82e-0419273523_UP
DrugNSC638615

TGM2 FUT3 FUT6 HCFC1

3.91e-04107734CID000097535
Drug0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A

LAMB4 ADAM23 SPOCK3 ZC3H13 NUP160

3.91e-041937354289_UP
DrugTestosterone propionate [57-85-2]; Up 200; 11.6uM; PC3; HT_HG-U133A

LAMB4 SCN11A JAG1 LRP2 ZNF510

3.91e-041937354676_UP
DrugClemastine fumarate [14976-57-9]; Up 200; 8.6uM; HL60; HT_HG-U133A

TRPS1 DNAI2 ZFYVE26 TEX15 CAMSAP1

3.91e-041937352412_UP
DrugBromperidol [10457-90-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A

CD82 THSD7A FN1 OAS2 FUT6

3.91e-041937352872_UP
DrugEtofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A

FN1 SPOCK3 PI4K2A FUT6 NUP160

3.91e-041937352093_UP
DrugAmiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A

SCN11A CD82 RBM5 TEX15 CAMSAP1

3.91e-041937353296_UP
DrugUrsolic acid [77-52-1]; Up 200; 8.8uM; PC3; HT_HG-U133A

DEAF1 SATB1 PI4K2A LRP2 FUT6

3.91e-041937352067_UP
DrugAlthiazide [5588-16-9]; Up 200; 10.4uM; HL60; HT_HG-U133A

LAMB4 SCN11A TEX15 RNF17 HCFC1

4.01e-041947352527_UP
DrugMeglumine [6284-40-8]; Up 200; 20.4uM; PC3; HT_HG-U133A

MCF2 OAS2 ADGRF5 FUT6 HCFC1

4.01e-041947356685_UP
DrugAcetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A

CD82 VPS39 JAG1 DNAI2 OAS2

4.01e-041947355384_DN
DrugPilocarpine nitrate [148-72-1]; Up 200; 14.8uM; PC3; HT_HG-U133A

CD82 DNAI2 PRKCQ FUT3 CAMSAP1

4.01e-041947356741_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A

SPOCK3 JAG1 MECOM TEX15 CAMSAP1

4.01e-041947354441_UP
DrugTribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A

FN1 GNPTAB DNAI2 TEX15 FUT6

4.01e-041947353507_UP
DrugVerteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A

LAMB4 FN1 GNPTAB PI4K2A FUT6

4.01e-041947353556_UP
DrugICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A

THSD7A FN1 ADAM23 PI4K2A HCFC1

4.01e-041947351179_DN
DrugMoricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A

DEAF1 FN1 CCSER2 CAMSAP1 SCIN

4.01e-041947352959_UP
DrugNaringenine [480-41-1]; Down 200; 14.6uM; MCF7; HT_HG-U133A

CD82 FN1 PI4K2A OAS2 MUC5B

4.01e-041947354422_DN
DrugBetonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A

CD82 DEAF1 FN1 LRP2 ADGRF5

4.01e-041947354301_DN
DrugSB 202190; Down 200; 1uM; PC3; HT_HG-U133A

FN1 PI4K2A RBM5 SCIN HCFC1

4.10e-041957357058_DN
DrugAH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A

JAG1 PI4K2A TTC27 CAMSAP1 NUP160

4.10e-041957356903_UP
DrugEthynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A

TGM2 EFNA3 ZC3H13 PI4K2A HCFC1

4.10e-041957354792_UP
DrugBenperidol [2062-84-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

EFNA3 ZNF556 MECOM MUC5B FUT6

4.10e-041957354781_UP
DrugPentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A

TGM2 SCN11A PI4K2A FUT6 HCFC1

4.10e-041957352290_UP
Diseasemyeloproliferative disorder

CHEK2 ZNF521 MECOM

3.21e-0525733EFO_0004251
Diseasecancer antigen 19.9 measurement

FUT3 FUT6

3.61e-054732EFO_0010584
Diseasepolyp of gallbladder

FUT3 FUT6

3.61e-054732MONDO_0021416
Diseasealpha-(1;3)-fucosyltransferase 5 measurement

FUT3 FUT6

3.61e-054732EFO_0021979
DiseaseAntiglaucoma preparations and miotics use measurement

THSD7A MECOM NUP160

3.63e-0526733EFO_0009944
Diseasedesmoglein-2 measurement

FUT3 FUT6

6.01e-055732EFO_0020322
Diseaselevel of V-set and immunoglobulin domain-containing protein 2 in blood serum

FUT3 FUT6

6.01e-055732OBA_2044774
Diseaselactoperoxidase measurement

FUT3 FUT6

9.00e-056732EFO_0020525
Diseaselithostathine-1-alpha measurement

FUT3 FUT6

1.26e-047732EFO_0801083
Diseasegalactoside 3(4)-L-fucosyltransferase measurement

FUT3 FUT6

1.26e-047732EFO_0021853
Diseasealpha-(1,3)-fucosyltransferase 5 measurement

FUT3 FUT6

1.26e-047732EFO_0020136
Diseaseferritin measurement

FN1 KIAA1328 FUT3 FUT6

2.21e-04119734EFO_0004459
DiseaseMalignant neoplasm of breast

TGM2 FN1 VPS39 JAG1 BTK CHEK2 TP53I3 MECOM ZFYVE26 CYB5R4

3.04e-0410747310C0006142
DiseaseBreast Carcinoma

TGM2 FN1 VPS39 JAG1 BTK CHEK2 MECOM

3.71e-04538737C0678222
Diseaseidiopathic pulmonary fibrosis

MUC5B FUT3 FUT6

3.86e-0457733EFO_0000768
Diseasecancer biomarker measurement

FUT3 FUT6

6.21e-0415732EFO_0005127
Diseasegalectin-3 measurement

FUT3 FUT6

7.08e-0416732EFO_0008137
DiseaseGlioblastoma

TGM2 FN1 JAG1

1.00e-0379733C0017636
Diseaseserum carcinoembryonic antigen measurement

FUT3 FUT6

1.11e-0320732EFO_0005760
DiseaseGiant Cell Glioblastoma

TGM2 FN1 JAG1

1.20e-0384733C0334588
DiseaseN-glycan measurement

FUT3 FUT6

1.35e-0322732EFO_0004999
Diseasee-selectin measurement

FUT3 FUT6

1.35e-0322732EFO_0004575
DiseaseMammary Carcinoma, Human

TGM2 FN1 VPS39 JAG1 CHEK2 MECOM

1.92e-03525736C4704874
DiseaseMammary Neoplasms, Human

TGM2 FN1 VPS39 JAG1 CHEK2 MECOM

1.92e-03525736C1257931
DiseaseMammary Neoplasms

TGM2 FN1 VPS39 JAG1 CHEK2 MECOM

1.95e-03527736C1458155
Diseasenecrotizing enterocolitis

TRPS1 KIAA1328

2.04e-0327732EFO_0003928
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

PCSK1 HMGCR CYB5R4

2.27e-03105733DOID:9352 (implicated_via_orthology)
Diseaseplatelet crit

EFNA3 DEAF1 FNTB CHEK2 MECOM HMGCR LY75 NUP160

2.40e-03952738EFO_0007985

Protein segments in the cluster

PeptideGeneStartEntry
YFTNCKQWYQRKICG

TGFBI

61

Q15582
NGECKTRDNQCQYIW

ADAM23

601

O75077
FWIDGQYLCCSQTAK

BTK

146

Q06187
NNKYVFCGWRNLICG

ADAM32

536

Q8TC27
LECVNDNYWFGRDKS

CHEK2

106

O96017
CYNGQIACWDTRKGS

DNAI2

236

Q9GZS0
ANLQWICAKAYGRDN

CAMSAP1

41

Q5T5Y3
DYVQAQVKCCGWVSF

CD82

141

P27701
CRNWEQEGVFKMCYN

MUC5B

1576

Q9HC84
CIGGSYWEKNVNCLA

TP53I3

216

Q53FA7
YKCDQCPKAFNWKSN

MECOM

291

Q03112
AQLRKGGYWYNCCTD

ANGPTL7

286

O43827
DGYRKAWNNQVCCKD

HCFC1

341

P51610
WGLNKQGYQCRQCNA

PRKCQ

181

Q04759
WIKDGYCDKACNNSA

GNPTAB

446

Q3T906
NSWLADKFCDQACNV

GNPTAB

511

Q3T906
MFTGNNKICGWNYEC

HMGCR

36

P04035
CEDNWEKNEQFGSCY

LY75

216

O60449
ACYNTSQKCDWKVDC

LRP2

156

P98164
TCGANKYRCDAKFRW

PLA2G12B

121

Q9BX93
KNNGMCRDGWNRYVC

NRXN1

686

Q9ULB1
YAWEQGCRKDNFDIA

OAS2

231

P29728
KFEDWLCNKCCLNNF

RBM5

181

P52756
RLDYNCLLKSNCDGW

KIAA1328

406

Q86T90
NTDRGNDNWLIKYDC

PI4K2A

306

Q9BTU6
YCNTSKKWFCNGRGN

UPF1

136

Q92900
WRKANKYQLCAQGVE

CCSER2

66

Q9H7U1
YRTCNASQGFKRWEC

EFNA3

96

P52797
VNYCSTFCQRKDWKD

DEAF1

521

O75398
CDSSRWCHDNGVNYK

FN1

2336

P02751
CSYNIGRAWNKPCEQ

FBN1

1721

P35555
FCKACWKLQEESRYQ

FUT6

336

P51993
IWRKYSECAFFQECQ

MCF2

601

P10911
RCNKLVDGCYSFWQA

FNTB

291

P49356
LGWLSYSKAQDDCNR

LAMB4

11

A4D0S4
TNWGGQLCDKDLNYC

JAG1

286

P78504
DFCKACWKLQQESRY

FUT3

336

P21217
ENAVYLCDREACFKW

USP9X

686

Q93008
SLDFWYCKRCKANIG

RBM6

536

P78332
EKACEAPQACQSYRW

THSD7A

821

Q9UPZ6
QWCGSSCNKYERLKA

SCIN

176

Q9Y6U3
LGNKACECYISIADW

SMG1

1186

Q96Q15
AAELLKQGAACNVWY

TNS3

1301

Q68CZ2
NKKDDCWICIRGFVY

CYB5R4

66

Q7L1T6
RNLQQEFWCKFYACC

NUP160

521

Q12769
VDYRAKLWACNFCFQ

SEC23B

76

Q15437
ANVSAAKCQEFGRWY

SATB1

226

Q01826
YKCVGSQWEEKRNDC

ADGRF5

706

Q8IZF2
CCGYLNVLVNQGWKE

AFAP1L1

421

Q8TED9
QACVAKFEDGIWYRA

RNF17

731

Q9BXT8
RVKYGQCWVFAAVAC

TGM2

271

P21980
LWRKNANGGYVCNAC

TRPS1

906

Q9UHF7
QVARYCGSQCQQKDW

ZMYND19

191

Q96E35
VSCKNCNSKLGWIYE

YPEL5

71

P62699
LARNFVNYSGCCEKW

RNF34

276

Q969K3
SNEKKVYRCTSCNWD

ZNF521

746

Q96K83
QCGKAYCWATSFQRH

ZNF556

291

Q9HAH1
ACNECGKTYRLNWEL

ZNF840P

446

A6NDX5
KDSLISNNEWCYCFQ

SPOCK3

296

Q9BQ16
FQCNECEKAFWDKSN

ZNF33A

356

Q06730
RCEAWGNKLYDSGNF

ZNF587B

121

E7ETH6
GQALCDSRKFGWEYN

TXNRD3

221

Q86VQ6
EKTYQCNECEKSFWR

ZNF510

541

Q9Y2H8
QEEKAYWCNQCGRNF

ZNF594

371

Q96JF6
IHQEAKAYWCNQCGR

ZNF594

561

Q96JF6
KAYWCNQCGRAFQGS

ZNF594

566

Q96JF6
QEKKVYWCNQCSRTF

ZNF594

756

Q96JF6
DFGIYLKWCEQNEQC

PLEKHG7

411

Q6ZR37
CGENLASKYLVWNCC

SCN11A

546

Q9UI33
GKNYECNQCWKTFGI

ZNF529

196

Q6P280
KSYAIICNNFWESCD

TEX15

1031

Q9BXT5
CLSKAYKCDTQSNCW

TTC27

736

Q6P3X3
LSCAVACDKEGWQYL

ZFYVE26

1451

Q68DK2
QCRNWLKTGNCLYGN

ZC3H13

41

Q5T200
RCEAWGNKLYDSGNF

ZNF814

121

B7Z6K7
AWCENSICVGFKRDY

VPS39

171

Q96JC1
KCEECNKAYRWFSDL

ZNF736

286

B4DX44
FCAWCALNSAKAKRQ

PCSK1

16

P29120