STRN4 ACSL3 RUFY1 TJP1 MTOR MUSK

MTOR HNRNPF

STRN4 EEF2K TJP1

FNIP1 MTOR

HEATR5A MTOR

NAPA EEF2K MTOR

Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure.

GRHL3 TJP1 ESRP1

Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin.

GRHL3 MTOR

Fluoxetine induces autophagic cell death via eEF2K-AMPK-mTOR-ULK complex axis in triple negative breast cancer.

EEF2K MTOR

A high-throughput approach for measuring temporal changes in the interactome.

STRN4 MTR RPL29 EEF2K GET4 RUFY1 MTOR HNRNPF KIF1B

Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves.

MTOR AVIL

Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway.

MTOR HNRNPF

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

FNIP1 EEF2K FOXN2 TJP1

Syntaxin13 expression is regulated by mammalian target of rapamycin (mTOR) in injured neurons to promote axon regeneration.

MTOR AVIL

The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.

TJP1 MTOR

Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain.

EEF2K MTOR

A COFRADIC protocol to study protein ubiquitination.

MTR GET4 ARID3A HNRNPF

The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members.

STRN4 TJP1

Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion.

MTOR AVIL

Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity.

TJP1 ESRP1

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.

FNIP1 MTOR

BRN2 as a key gene drives the early primate telencephalon development.

SOX1 TJP1

Periderm Fate during Palatogenesis: TGF-β and Periderm Dedifferentiation.

GRHL3 TJP1

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

STRN4 ACSL3 TJP1 MTOR

Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site.

EEF2K MTOR

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.

SOX1 TJP1

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

MTR FNIP1 EEF2K TJP1

cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.

EEF2K MTOR

mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis.

TJP1 MTOR

Epithelial Migration and Non-adhesive Periderm Are Required for Digit Separation during Mammalian Development.

GRHL3 TJP1

A central chaperone-like role for 14-3-3 proteins in human cells.

FNIP1 TJP1 MTOR TMCC1 MUSK KIF1B

Deletion of Yy1 in mouse lung epithelium unveils molecular mechanisms governing pleuropulmonary blastoma pathogenesis.

TJP1 ESRP1

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.

GRHL3 TJP1

The Mediator complex protein Med31 is required for embryonic growth and cell proliferation during mammalian development.

MTOR MED31

CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.

TJP1 MTOR

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ACSL3 NAPA RPL29 TJP1 MTOR HNRNPF KIF1B

OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer.

MTOR HNRNPF

Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2.

MTR MTOR

Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.

TJP1 KIF1B

Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex.

RPL29 GET4

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

HNRNPF ISY1

Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.

SOX1 MTR

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

IFT80 TJP1 MTOR

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure.

GRHL3 ESRP1

Transcription factor protein interactomes reveal genetic determinants in heart disease.

ARID3A LCORL HNRNPF MED31

mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics.

TJP1 MTOR

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

MTR ARID3A MTOR ISY1

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis.

RPL29 TJP1 HNRNPF

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

RPL29 EEF2K RUFY1 TJP1 KIF1B

Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.

MTR GET4 HNRNPF

Network organization of the human autophagy system.

NAPA FNIP1 TJP1 MTOR

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

STRN4 ACSL3 TJP1 KIF1B

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

IFT80 MTOR

Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation.

STRN4 RPL29 HNRNPF

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

ACSL3 NAPA TJP1 HNRNPF

MTOR KIF1B

FAM184B LCORL

GRHL3 MTOR KIF1B

ARID3A CAPS

HEATR5A GRHL3 TMCC1 KIF1B

FOXN2 HEATR5A LCORL KIF1B

GRHL3 LCORL

LCORL TJP1 MTOR

MTR GRHL3

FOXN2 IFT80 GRHL3 LCORL MUSK

RUFY1 LCORL

HEATR5A IFT80 LCORL MUSK

AVIL

731

CAPS

86

ESRP1

491

ISY1

1

KIF1B

196

MED31

1

LCORL

1

FAM184B

861

IFT80

621

HEATR5A

191

GRHL3

41

FNIP1

371

FOXN2

231

EEF2K

696

EFCAB3

201

MTOR

1506

HNRNPF

341

RPL29

56

GET4

1

RUFY1

101

MTR

116

NAPA

1

SOX1

196

ACSL3

256

ARID3A

51

TMCC1

166

TJP1

1

STRN4

1

MUSK

616